LOCUS       DBJKQU010000001       118351 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.001, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000001 DBJKQU010000000
VERSION     DBJKQU010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 118351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118351
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.001"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..144
                     /locus_tag="ACSUUC_000001"
     CDS             <1..144
                     /locus_tag="ACSUUC_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HHQ8053319.1"
                     /translation="KERSKVENIFAKVKTFKIFSTTYRNHRKRFGLRMNLIAGIINHE
                     LGF"
     gene            complement(216..542)
                     /locus_tag="ACSUUC_000002"
     CDS             complement(216..542)
                     /locus_tag="ACSUUC_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1096 element passenger TnpR family protein"
                     /protein_id="HHQ8053320.1"
                     /translation="MILWSFDFANDHAHTFFMDNVEWSHADSYFLSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDG
                     FDYEEW"
     gene            complement(869..2749)
                     /locus_tag="ACSUUC_000003"
     CDS             complement(869..2749)
                     /locus_tag="ACSUUC_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HHQ8053321.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2743..3612)
                     /locus_tag="ACSUUC_000004"
     CDS             complement(2743..3612)
                     /locus_tag="ACSUUC_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HHQ8053322.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3696..6341)
                     /locus_tag="ACSUUC_000005"
     CDS             complement(3696..6341)
                     /locus_tag="ACSUUC_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HHQ8053323.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAVFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPELL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKDHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RLYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(6432..7712)
                     /locus_tag="ACSUUC_000006"
     CDS             complement(6432..7712)
                     /locus_tag="ACSUUC_000006"
                     /EC_number="3.2.1.163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HHQ8053324.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VVATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7883..9967
                     /locus_tag="ACSUUC_000007"
     CDS             7883..9967
                     /locus_tag="ACSUUC_000007"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HHQ8053325.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNPLMLFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKSSAQADWENLLHRFDIIEIGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKLGILFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTSFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLTQYQELGYLSTDHNESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(10007..11686)
                     /locus_tag="ACSUUC_000008"
     CDS             complement(10007..11686)
                     /locus_tag="ACSUUC_000008"
                     /EC_number="3.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004560 - alpha-L-fucosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HHQ8053326.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFKKWFETTRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDAALPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSMPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12441..13670
                     /gene="arcA"
                     /locus_tag="ACSUUC_000009"
     CDS             12441..13670
                     /gene="arcA"
                     /locus_tag="ACSUUC_000009"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HHQ8053327.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHDIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13728..14744
                     /gene="argF"
                     /locus_tag="ACSUUC_000010"
     CDS             13728..14744
                     /gene="argF"
                     /locus_tag="ACSUUC_000010"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - L-arginine biosynthetic process
                     via ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HHQ8053328.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14909..15856
                     /gene="arcC"
                     /locus_tag="ACSUUC_000011"
     CDS             14909..15856
                     /gene="arcC"
                     /locus_tag="ACSUUC_000011"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HHQ8053329.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            16065..17576
                     /locus_tag="ACSUUC_000012"
     CDS             16065..17576
                     /locus_tag="ACSUUC_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HHQ8053330.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17598..18929
                     /locus_tag="ACSUUC_000013"
     CDS             17598..18929
                     /locus_tag="ACSUUC_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HHQ8053331.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGTFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            19025..19100
                     /locus_tag="ACSUUC_000014"
                     /pseudo
     CDS             19025..19100
                     /locus_tag="ACSUUC_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(19336..19626)
                     /locus_tag="ACSUUC_000015"
     CDS             complement(19336..19626)
                     /locus_tag="ACSUUC_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HHQ8053332.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(19614..19865)
                     /locus_tag="ACSUUC_000016"
     CDS             complement(19614..19865)
                     /locus_tag="ACSUUC_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HHQ8053333.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(20264..21148)
                     /locus_tag="ACSUUC_000017"
     CDS             complement(20264..21148)
                     /locus_tag="ACSUUC_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HHQ8053334.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(21293..22444)
                     /locus_tag="ACSUUC_000018"
     CDS             complement(21293..22444)
                     /locus_tag="ACSUUC_000018"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HHQ8053335.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(22590..24356)
                     /locus_tag="ACSUUC_000019"
     CDS             complement(22590..24356)
                     /locus_tag="ACSUUC_000019"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HHQ8053336.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(24369..25097)
                     /locus_tag="ACSUUC_000020"
     CDS             complement(24369..25097)
                     /locus_tag="ACSUUC_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HHQ8053337.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIKMHIWCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            complement(25112..28129)
                     /locus_tag="ACSUUC_000021"
     CDS             complement(25112..28129)
                     /locus_tag="ACSUUC_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 98 domain-containing
                     protein"
                     /protein_id="HHQ8053338.1"
                     /translation="MESKKIAKQILIATAVLTSFLGSNLVYADVVQSNSNNRASTETA
                     RVTGNNLEKLITKDKEIDKEMTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHT
                     KISLLTSDDKVKYFDKGIGTVADSPSVISYDISGQGFEKFETYIGIDQSANSSRSDHA
                     VVDRIEIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGD
                     EVVFADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPF
                     TPGNNGSNNKIKLLIDGKEVEFNKGLGTVASNPSSIKYDVSGANVTRFISYVGIDRSA
                     NHLNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIPKDTQTIELKSY
                     SGKHTWADELVLGGALFMANGKFKNPNDWSEVDKRREINNEHPLLMMPLYANGEEFNQ
                     GKYTFWGGDTLTGKWENIPDDLKPYTVIQLHPDDLTKRDGAARDFYEHMLEEAAKYVN
                     PKTGKNEPIPVILTVYTAGNMPYYTSAHWLSTSWIDKMYQKYPNLHGIFSTENYWIWA
                     NDIENKAADYLKVSAKNGGYFIWAEQNNGSAIEKAFGKNGKIAFQKSVDKYWKNLIFM
                     FKNTPAAEGNDSTTESYMKGLWLSNHTYQWGGLMDTWKWYETGKWKLFASGNIGKSQG
                     DRQWLTEPESMLGEEALGVYLNGGVVYNFEHPAYTYGVNNKESLLFSEVIKEFFRYVI
                     AHPAPSKEKVLEDTKVFIHGDYSNKGNGKFFVNVNTDREQTPLYMTGRYNVIPAIPGV
                     LKTDKLKESVSGSRIQIKEITSPEFSSTQARKEYLNKLYPMNYEGDIFAQKLDNRWFV
                     YNYKVNENVKQTGKLKFNSLEMDVEFEPHTYGIFERISNGLKVNLNNFRTNKDSLWSN
                     AQDANQAKKLPQLTKKGAIKWIEEHYIKDTQFGEKRVTKIVLRGIDKLPTIHSLSGTN
                     NSYDQPSLNFDQKNHMVTITINSNGNLEFELHF"
     gene            complement(28140..30356)
                     /locus_tag="ACSUUC_000022"
     CDS             complement(28140..30356)
                     /locus_tag="ACSUUC_000022"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004557 - alpha-galactosidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HHQ8053339.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCVETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEVYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLSTEKILDLAKAAKDLGIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADEIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSGRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYRSLFQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSRFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            complement(30378..32248)
                     /locus_tag="ACSUUC_000023"
                     /pseudo
     CDS             complement(30378..32248)
                     /locus_tag="ACSUUC_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
     gene            complement(32254..33573)
                     /locus_tag="ACSUUC_000024"
     CDS             complement(32254..33573)
                     /locus_tag="ACSUUC_000024"
                     /EC_number="3.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004560 - alpha-L-fucosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HHQ8053340.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDRYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            complement(33570..34409)
                     /locus_tag="ACSUUC_000025"
     CDS             complement(33570..34409)
                     /locus_tag="ACSUUC_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHQ8053341.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPIDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSCSGIAMSFFII
                     KNYFEIIPKELEEAAEIDGATYAQTFWKVMLPIARPGILTAAVLAFINNWNEYYWASM
                     LVIDKNELTVPALLGQFTTSFNTNYNGLFSAIVVIVLPPIILFAFTSKYFIEALGGGA
                     VKG"
     gene            complement(34412..35341)
                     /locus_tag="ACSUUC_000026"
     CDS             complement(34412..35341)
                     /locus_tag="ACSUUC_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHQ8053342.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIVCINILFRERKRLKGGK"
     gene            35374..36015
                     /locus_tag="ACSUUC_000027"
                     /pseudo
     CDS             35374..36015
                     /locus_tag="ACSUUC_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
     gene            complement(37144..38649)
                     /gene="adcA"
                     /locus_tag="ACSUUC_000028"
     CDS             complement(37144..38649)
                     /gene="adcA"
                     /locus_tag="ACSUUC_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HHQ8053343.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(38659..39465)
                     /locus_tag="ACSUUC_000029"
     CDS             complement(38659..39465)
                     /locus_tag="ACSUUC_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HHQ8053344.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(39458..40162)
                     /locus_tag="ACSUUC_000030"
     CDS             complement(39458..40162)
                     /locus_tag="ACSUUC_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053345.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNVGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(40162..40602)
                     /gene="adcR"
                     /locus_tag="ACSUUC_000031"
     CDS             complement(40162..40602)
                     /gene="adcR"
                     /locus_tag="ACSUUC_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HHQ8053346.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(40757..42025)
                     /gene="dltD"
                     /locus_tag="ACSUUC_000032"
     CDS             complement(40757..42025)
                     /gene="dltD"
                     /locus_tag="ACSUUC_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HHQ8053347.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(42018..42257)
                     /gene="dltC"
                     /locus_tag="ACSUUC_000033"
     CDS             complement(42018..42257)
                     /gene="dltC"
                     /locus_tag="ACSUUC_000033"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HHQ8053348.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(42271..43515)
                     /gene="dltB"
                     /locus_tag="ACSUUC_000034"
     CDS             complement(42271..43515)
                     /gene="dltB"
                     /locus_tag="ACSUUC_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HHQ8053349.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVIT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(43512..45062)
                     /gene="dltA"
                     /locus_tag="ACSUUC_000035"
     CDS             complement(43512..45062)
                     /gene="dltA"
                     /locus_tag="ACSUUC_000035"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HHQ8053350.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(45083..45214)
                     /locus_tag="ACSUUC_000036"
     CDS             complement(45083..45214)
                     /locus_tag="ACSUUC_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HHQ8053351.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(45445..46149)
                     /locus_tag="ACSUUC_000037"
     CDS             complement(45445..46149)
                     /locus_tag="ACSUUC_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HHQ8053352.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAYLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(46219..48045)
                     /gene="glpO"
                     /locus_tag="ACSUUC_000038"
     CDS             complement(46219..48045)
                     /gene="glpO"
                     /locus_tag="ACSUUC_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HHQ8053353.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(48087..49595)
                     /gene="glpK"
                     /locus_tag="ACSUUC_000039"
     CDS             complement(48087..49595)
                     /gene="glpK"
                     /locus_tag="ACSUUC_000039"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HHQ8053354.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(49754..51181)
                     /locus_tag="ACSUUC_000040"
                     /pseudo
     CDS             complement(49754..51181)
                     /locus_tag="ACSUUC_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            51346..52218
                     /gene="hslO"
                     /locus_tag="ACSUUC_000041"
     CDS             51346..52218
                     /gene="hslO"
                     /locus_tag="ACSUUC_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HHQ8053355.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            52205..53185
                     /gene="dusB"
                     /locus_tag="ACSUUC_000042"
     CDS             52205..53185
                     /gene="dusB"
                     /locus_tag="ACSUUC_000042"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HHQ8053356.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLID
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(53415..55502)
                     /gene="pspC"
                     /locus_tag="ACSUUC_000043"
     CDS             complement(53415..55502)
                     /gene="pspC"
                     /locus_tag="ACSUUC_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HHQ8053357.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVAVASLFLGGVVHAEGVGGRN
                     TSTVTSSGQDTSKKYADEVKSHYQSILEKVRKSLEKDRHTQNVGLITKLSEIKKKYLY
                     ELEVNVLLEEKSKAELPSKAKAELDAAFEQFKKEPELTKKVAEAQKKVEEAKKKAEDQ
                     KEEDFRNYPTNTYKTIELEIAESDVKVKEAELELLKEEAKEHRDEGTIKQVEEKVKSE
                     KAEATRLEEIKTERKKAEEEAKRRADAKEQGKPKGRAKRGVPGEQATPDKKENDAKSS
                     DSSVGEETLPNPSLKPEKKVAEAQKKVEEAKKKAKDQKEEDHRNYPTITYKTLELEIA
                     ESDVEVKKAELELVKEEAKGSRNEEKVKQAKAEVESKKAEATRLEKIKTDRKKAEEAK
                     RKAAEEDKVKEKPAEQPQPAPAPQPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARR
                     SEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYY
                     LNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQNNGSW
                     YYLNANGAMATGWLQNNGSWYYLNANGDMATGWLQNNGSWYYLNANGSMVTGWLQNNG
                     SWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTV
                     DSYRVNANGEWVN"
     gene            complement(55581..56108)
                     /locus_tag="ACSUUC_000044"
     CDS             complement(55581..56108)
                     /locus_tag="ACSUUC_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HHQ8053358.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(56191..57531)
                     /gene="hk06"
                     /locus_tag="ACSUUC_000045"
     CDS             complement(56191..57531)
                     /gene="hk06"
                     /locus_tag="ACSUUC_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HHQ8053359.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(57528..58181)
                     /gene="rr06"
                     /locus_tag="ACSUUC_000046"
     CDS             complement(57528..58181)
                     /gene="rr06"
                     /locus_tag="ACSUUC_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HHQ8053360.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(58442..60874)
                     /locus_tag="ACSUUC_000047"
     CDS             complement(58442..60874)
                     /locus_tag="ACSUUC_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HHQ8053361.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(60876..61334)
                     /locus_tag="ACSUUC_000048"
     CDS             complement(60876..61334)
                     /locus_tag="ACSUUC_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HHQ8053362.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            complement(61453..62181)
                     /locus_tag="ACSUUC_000049"
     CDS             complement(61453..62181)
                     /locus_tag="ACSUUC_000049"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053363.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(62181..63188)
                     /locus_tag="ACSUUC_000050"
     CDS             complement(62181..63188)
                     /locus_tag="ACSUUC_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHQ8053364.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(63227..63985)
                     /locus_tag="ACSUUC_000051"
     CDS             complement(63227..63985)
                     /locus_tag="ACSUUC_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8053365.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            complement(63948..64238)
                     /locus_tag="ACSUUC_000052"
     CDS             complement(63948..64238)
                     /locus_tag="ACSUUC_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HHQ8053366.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQGADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            complement(64494..65840)
                     /gene="cbpD"
                     /locus_tag="ACSUUC_000053"
     CDS             complement(64494..65840)
                     /gene="cbpD"
                     /locus_tag="ACSUUC_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HHQ8053367.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEMPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGHSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGYKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     gene            complement(65929..66195)
                     /locus_tag="ACSUUC_000054"
     CDS             complement(65929..66195)
                     /locus_tag="ACSUUC_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HHQ8053368.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(66197..67549)
                     /gene="dnaB"
                     /locus_tag="ACSUUC_000055"
     CDS             complement(66197..67549)
                     /gene="dnaB"
                     /locus_tag="ACSUUC_000055"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HHQ8053369.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(67593..68045)
                     /gene="rplI"
                     /locus_tag="ACSUUC_000056"
     CDS             complement(67593..68045)
                     /gene="rplI"
                     /locus_tag="ACSUUC_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HHQ8053370.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(68042..70015)
                     /locus_tag="ACSUUC_000057"
     CDS             complement(68042..70015)
                     /locus_tag="ACSUUC_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HHQ8053371.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSKAGEKLTEIVLNEIKEKEKEE"
     gene            complement(70151..70699)
                     /gene="hpf"
                     /locus_tag="ACSUUC_000058"
     CDS             complement(70151..70699)
                     /gene="hpf"
                     /locus_tag="ACSUUC_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation-promoting factor, HPF/YfiA
                     family"
                     /protein_id="HHQ8053372.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(70779..71441)
                     /locus_tag="ACSUUC_000059"
     CDS             complement(70779..71441)
                     /locus_tag="ACSUUC_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HHQ8053373.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(71438..72736)
                     /locus_tag="ACSUUC_000060"
     CDS             complement(71438..72736)
                     /locus_tag="ACSUUC_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HHQ8053374.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            72792..73427
                     /locus_tag="ACSUUC_000061"
     CDS             72792..73427
                     /locus_tag="ACSUUC_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HHQ8053375.1"
                     /translation="MEFRTIKEDDQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKTTHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            73712..74632
                     /gene="cysK"
                     /locus_tag="ACSUUC_000062"
     CDS             73712..74632
                     /gene="cysK"
                     /locus_tag="ACSUUC_000062"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HHQ8053376.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(74871..75245)
                     /locus_tag="ACSUUC_000063"
                     /pseudo
     CDS             complement(74871..75245)
                     /locus_tag="ACSUUC_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            75218..75526
                     /locus_tag="ACSUUC_000064"
                     /pseudo
     CDS             75218..75526
                     /locus_tag="ACSUUC_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(75717..76004)
                     /gene="tnpB"
                     /locus_tag="ACSUUC_000065"
     CDS             complement(75717..76004)
                     /gene="tnpB"
                     /locus_tag="ACSUUC_000065"
                     /inference="COORDINATES: protein motif:HMM:NF017528.6"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HHQ8053377.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(76250..77290)
                     /gene="tsf"
                     /locus_tag="ACSUUC_000066"
     CDS             complement(76250..77290)
                     /gene="tsf"
                     /locus_tag="ACSUUC_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HHQ8053378.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            complement(77369..78148)
                     /gene="rpsB"
                     /locus_tag="ACSUUC_000067"
     CDS             complement(77369..78148)
                     /gene="rpsB"
                     /locus_tag="ACSUUC_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HHQ8053379.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            complement(78372..79550)
                     /gene="pcsB"
                     /locus_tag="ACSUUC_000068"
     CDS             complement(78372..79550)
                     /gene="pcsB"
                     /locus_tag="ACSUUC_000068"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HHQ8053380.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            complement(79644..80138)
                     /gene="mreD"
                     /locus_tag="ACSUUC_000069"
     CDS             complement(79644..80138)
                     /gene="mreD"
                     /locus_tag="ACSUUC_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HHQ8053381.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            complement(80138..80956)
                     /gene="mreC"
                     /locus_tag="ACSUUC_000070"
     CDS             complement(80138..80956)
                     /gene="mreC"
                     /locus_tag="ACSUUC_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HHQ8053382.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            complement(81015..81809)
                     /locus_tag="ACSUUC_000071"
     CDS             complement(81015..81809)
                     /locus_tag="ACSUUC_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T family protein"
                     /protein_id="HHQ8053383.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKSMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            complement(81802..82641)
                     /locus_tag="ACSUUC_000072"
     CDS             complement(81802..82641)
                     /locus_tag="ACSUUC_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HHQ8053384.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            complement(82626..83453)
                     /locus_tag="ACSUUC_000073"
     CDS             complement(82626..83453)
                     /locus_tag="ACSUUC_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HHQ8053385.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALDLVGMLDFKKREPARLSGGQKQRVAIAGVVVLRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSHNGYNLPENYLTESELEDKLWELL"
     gene            complement(83450..83995)
                     /gene="pgsA"
                     /locus_tag="ACSUUC_000074"
     CDS             complement(83450..83995)
                     /gene="pgsA"
                     /locus_tag="ACSUUC_000074"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HHQ8053386.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            complement(84006..84827)
                     /gene="rodZ"
                     /locus_tag="ACSUUC_000075"
     CDS             complement(84006..84827)
                     /gene="rodZ"
                     /locus_tag="ACSUUC_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HHQ8053387.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            complement(84869..86152)
                     /gene="yfmH"
                     /locus_tag="ACSUUC_000076"
     CDS             complement(84869..86152)
                     /gene="yfmH"
                     /locus_tag="ACSUUC_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P 5-aminopentanol modification-associated
                     protein YfmH"
                     /protein_id="HHQ8053388.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLIVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            complement(86149..87399)
                     /gene="yfmF"
                     /locus_tag="ACSUUC_000077"
                     /pseudo
     CDS             complement(86149..87399)
                     /gene="yfmF"
                     /locus_tag="ACSUUC_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P 5-aminopentanol modification-associated
                     protein YfmF"
     gene            87558..87926
                     /gene="yaaA"
                     /locus_tag="ACSUUC_000078"
     CDS             87558..87926
                     /gene="yaaA"
                     /locus_tag="ACSUUC_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HHQ8053389.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            87929..89026
                     /gene="recF"
                     /locus_tag="ACSUUC_000079"
     CDS             87929..89026
                     /gene="recF"
                     /locus_tag="ACSUUC_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="All proteins in this family for which functions are
                     known are DNA-binding proteins that assist the
                     filamentation of RecA onto DNA for the initiation of
                     recombination or recombinational repair; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HHQ8053390.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(89077..90555)
                     /gene="guaB"
                     /locus_tag="ACSUUC_000080"
     CDS             complement(89077..90555)
                     /gene="guaB"
                     /locus_tag="ACSUUC_000080"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HHQ8053391.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(90707..91732)
                     /gene="trpS"
                     /locus_tag="ACSUUC_000081"
     CDS             complement(90707..91732)
                     /gene="trpS"
                     /locus_tag="ACSUUC_000081"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HHQ8053392.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            91938..93560
                     /locus_tag="ACSUUC_000082"
     CDS             91938..93560
                     /locus_tag="ACSUUC_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHQ8053393.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            93622..96255
                     /locus_tag="ACSUUC_000083"
     CDS             93622..96255
                     /locus_tag="ACSUUC_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HHQ8053394.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFNLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKADSLFGIQYNISDSPIDKYGFKDIYQKDNLTLYENQYSLPIAVASQSVY
                     NDVKFNEHTLDNQASFLNQLANVNFDYFSPIPYEKTEKIENTNDLISVTSSSNEDAAI
                     QYQIEVPENSQVYLSFINLHFSNDKQKKVDILVNGEKKTFTTDNVFSFFNLGYTKEKK
                     TFNINVSFPGNSQVSFESPTFYRLDTKTFTEAIQKIKEQPVTVSTSKNKVFATYDVQQ
                     DTSIFFTIPYDKGWSAYQDGKKIEIKQAQTGFMKVDIPKGKGTITLSFIPNGFITGAI
                     CSFTSLLLFGIYNHRRKSSKA"
     gene            complement(96285..97938)
                     /locus_tag="ACSUUC_000084"
                     /pseudo
     CDS             complement(96285..97938)
                     /locus_tag="ACSUUC_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472064.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            98066..98608
                     /locus_tag="ACSUUC_000085"
     CDS             98066..98608
                     /locus_tag="ACSUUC_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHQ8053395.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(98649..98722)
                     /locus_tag="ACSUUC_000086"
     tRNA            complement(98649..98722)
                     /locus_tag="ACSUUC_000086"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(98686..98688),aa:Asn,seq:gtt)
     gene            complement(98728..98799)
                     /locus_tag="ACSUUC_000087"
     tRNA            complement(98728..98799)
                     /locus_tag="ACSUUC_000087"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(98764..98766),aa:Glu,seq:ttc)
     gene            complement(98851..99603)
                     /gene="comE"
                     /locus_tag="ACSUUC_000088"
     CDS             complement(98851..99603)
                     /gene="comE"
                     /locus_tag="ACSUUC_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HHQ8053396.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(99600..100925)
                     /gene="comD"
                     /locus_tag="ACSUUC_000089"
     CDS             complement(99600..100925)
                     /gene="comD"
                     /locus_tag="ACSUUC_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HHQ8053397.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            complement(100946..101071)
                     /gene="comC"
                     /locus_tag="ACSUUC_000090"
     CDS             complement(100946..101071)
                     /gene="comC"
                     /locus_tag="ACSUUC_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HHQ8053398.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            complement(101236..101309)
                     /locus_tag="ACSUUC_000091"
     tRNA            complement(101236..101309)
                     /locus_tag="ACSUUC_000091"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(101273..101275),aa:Arg,seq:tct)
     gene            complement(101353..101832)
                     /gene="rlmH"
                     /locus_tag="ACSUUC_000092"
     CDS             complement(101353..101832)
                     /gene="rlmH"
                     /locus_tag="ACSUUC_000092"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HHQ8053399.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            102015..103196
                     /locus_tag="ACSUUC_000093"
     CDS             102015..103196
                     /locus_tag="ACSUUC_000093"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HHQ8053400.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            103254..104012
                     /locus_tag="ACSUUC_000094"
     CDS             103254..104012
                     /locus_tag="ACSUUC_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HHQ8053401.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEALAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            104225..105586
                     /gene="dnaA"
                     /locus_tag="ACSUUC_000095"
     CDS             104225..105586
                     /gene="dnaA"
                     /locus_tag="ACSUUC_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HHQ8053402.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            105745..106881
                     /gene="dnaN"
                     /locus_tag="ACSUUC_000096"
     CDS             105745..106881
                     /gene="dnaN"
                     /locus_tag="ACSUUC_000096"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HHQ8053403.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNITITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            106946..107140
                     /locus_tag="ACSUUC_000097"
     CDS             106946..107140
                     /locus_tag="ACSUUC_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HHQ8053404.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            107224..108339
                     /gene="ychF"
                     /locus_tag="ACSUUC_000098"
     CDS             107224..108339
                     /gene="ychF"
                     /locus_tag="ACSUUC_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HHQ8053405.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRASYHLLGLGTYFTAGEKEVRAWTFKRGMKATQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            108410..108979
                     /gene="pth"
                     /locus_tag="ACSUUC_000099"
     CDS             108410..108979
                     /gene="pth"
                     /locus_tag="ACSUUC_000099"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - peptidyl-tRNA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HHQ8053406.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            108980..112489
                     /gene="mfd"
                     /locus_tag="ACSUUC_000100"
     CDS             108980..112489
                     /gene="mfd"
                     /locus_tag="ACSUUC_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HHQ8053407.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKVPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASHPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSCLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIVENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            112547..112813
                     /locus_tag="ACSUUC_000101"
     CDS             112547..112813
                     /locus_tag="ACSUUC_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HHQ8053408.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            112806..113174
                     /locus_tag="ACSUUC_000102"
     CDS             112806..113174
                     /locus_tag="ACSUUC_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HHQ8053409.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            113179..113301
                     /locus_tag="ACSUUC_000103"
     CDS             113179..113301
                     /locus_tag="ACSUUC_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HHQ8053410.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            113294..114562
                     /locus_tag="ACSUUC_000104"
     CDS             113294..114562
                     /locus_tag="ACSUUC_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HHQ8053411.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKISFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            114559..115836
                     /gene="tilS"
                     /locus_tag="ACSUUC_000105"
     CDS             114559..115836
                     /gene="tilS"
                     /locus_tag="ACSUUC_000105"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HHQ8053412.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFKKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRNAILGISNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            115840..116382
                     /gene="hpt"
                     /locus_tag="ACSUUC_000106"
     CDS             115840..116382
                     /gene="hpt"
                     /locus_tag="ACSUUC_000106"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HHQ8053413.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            116398..>118351
                     /gene="ftsH"
                     /locus_tag="ACSUUC_000107"
     CDS             116398..>118351
                     /gene="ftsH"
                     /locus_tag="ACSUUC_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HHQ8053414.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT        36332 a        24666 c        20920 g        36433 t
ORIGIN      
        1 aaggagagaa gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa aatattttca
       61 acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgat tgctggtatt
      121 atcaatcatg aactaggatt ctagttttgc aggaagtcta ttgaaatact aagcctacac
      181 acagactgat tccaattgtt ttttagattt caattttacc attcttcata gtcaaaacca
      241 tcataatctg gatattgttc tggcgacgtt ccaaccgaac gtacgagata agcttcttcg
      301 tcctctgtct cgatttctct cagcacttgg cattcaaaac gccattcatc accgaagtcg
      361 aaaataaact taaatttttg tttgacactt aggctatcca gatagacatt ttctgtgtaa
      421 cgttcttcaa catcgtcact aacaaagcta agaaagtaag aatctgcatg actccactca
      481 acattatcca tgaaaaatgt gtgagcatga tcatttgcaa aatcaaaact ccataaaatc
      541 acatctgcta gttccgctaa cgtttttgtt tttggaatct atatatgtcg gtagcaacct
      601 tttttaaatt tgacggaaat gatccaagct tctacagatg ctggcttttc agcttctatt
      661 tcttgtttta ctaattttaa ctgtagcatt tgaaaccaga taattcttct gtttcacgcg
      721 aaacaccctg cgccaagcaa ggtgttcttg tttttatact caatgaaaat caaagagcaa
      781 actaggaagc tagctgcagg ctgctcaaaa cactgttttg aggttgtaga tggaagctga
      841 cgtggtttga agagattttc gaagagtatt aagtcgtata aatcgtcgac gctgtcgcaa
      901 tggtatgcca ctggttggct gttgtagctg cgaaatcctt gtctgcgtag aagtcagtaa
      961 atggtaggat ttcaacttcc agctcgtcga tgcggtcaag ctggccagcc agataaacct
     1021 cgatacggct ttctgctcgt ttgatgcgtt gcaagagtcc gcccatacgg atgtcaactg
     1081 tatccaaacc aaagaccttg ttttctttca gccattggtg gctaaagagg gcatggaagt
     1141 cttcaatttg gcttctaagt tctggtaatt cttgtctggc gatttgttgt aaactttctt
     1201 tatcatccgc ttggtaggcc tgacgaatac gtcgtcccac atctactttg ctacttaaaa
     1261 tagcattcaa ctgggcctga gtttcaaaga gataagcata gtttccagct ttttctttaa
     1321 tgttagcaag cgtctcagca gcctgagcga agtgtggctt gtcctgttca ggtgtcatgt
     1381 gtcggtcaag tatcggacag agaacatcct gataaaagac atatcggttg ggattgatgc
     1441 cactgagatt acctggtagg tctggtaaaa ggttggcaag gtcaatctgc ataaaatctt
     1501 caaccgttag accagtattg gtcttgaaat gcgcagacaa actatctagg tcattgcgat
     1561 agctgagttc tgcccagatt tgcaagcttg gtaggataga gaactgggca gtttcaccac
     1621 cattgtctcc ccaacccgtt acgatgactt ctttaatctg attggcacgg caggctttat
     1681 tagcctcgat agccactaga cggctaaaat ggttgtgagg tgtaaagcca atccacttcc
     1741 aagctccccc tgcaaatgca aggtcatggc taatcttgtg atgattgcgg aaattacggt
     1801 tgtatttttc ctcgctatcc tgataataat cccagtaaac cagagtcaca cggtctttga
     1861 gacggtctag gtagacacga gtttcctctg gaatttccac atcacggtcg tactggccat
     1921 ccgctgacat gagtttgaag aacatatcac tccacatctg gcagtggaaa ccatatttgt
     1981 cagcaatatc cagcacgcgc tccaagtgtt ggcacatgag gagactacga tccacaacac
     2041 cgttcaaaat caggtagcgt cccaaaccaa ccaagtgggc ttcgtccatc ccgatattga
     2101 ccttgcgagt cttcagttta gacaacgtgg caaacatgcc atcaatcagg tcataaacct
     2161 tttcttcgcc aatgagaaga atgtcctcta catcacggag ctcctgcact tccttgacac
     2221 cccatttgac aaaggccgac aagtgggcca aggtctggat gcatggtaca aaggtcatgt
     2281 caaactgttg agcataggct tcgatttcct gcaactcctc tgctgaataa gctccacgga
     2341 aatagccaaa gtaaggctgc ccttcaatct ggtaagtgtc ttccatgtaa agttcaaagg
     2401 ttgagtagcc catgagagcc aagacctcaa tcatctgctt ggcagaagcc acattcagca
     2461 ccgcatttcg agaacagtca accatgtaag ccaaatcttc gtaagctgct tgttcctcaa
     2521 tctctacttt atcagcttct gctagaactg ttaccaacaa ggataaggca cgataaagtt
     2581 ggtgaggttt gcggtaggtc aattgatagt gaccttcctc accctcgata gagatagagg
     2641 cttggtcaga ctgagtgaca gccacttcca catctggtag agaaatgtga ccttttaaaa
     2701 cctcaatagc ttgcgtttgt ttgggactaa gtcctgtaaa tcttaccatt gcttttcctc
     2761 ctgtagccag ttgacaaggg caccgtagag attggcatct gcgtgatagg tgcaggtctg
     2821 gataactggt gcgaccgtgt attcttcgta ggcatcgaca aagtcttcaa cagccttctt
     2881 aacaccttgg ataaaatctg gattttgact gatagagcca cccagactga tgacatctgg
     2941 atcgatcaga tactggatat tgagcaagcc ttgcgtcaga ttgcggttca tgcgctcaat
     3001 ggcttcttga caaagagcat taccagctgc ggcctcttgg taaatcttgc gaccgtccca
     3061 atcagtatga ccagattttt caatcacgta tcgtaccata ttcccagttg atgctagttg
     3121 cgaccagtta ttaagttttt cagcaggggc aagggttgtc atgtagccaa attctccacc
     3181 cagaccgtgg cgacctcgat gaagtctacc attgataatc atggctccgc caatccctgt
     3241 cccaatcacg acacaggctg cattttcaag ctctggatga gctagtagtt cactgagtcc
     3301 aacgcagttg gcatcatttt ctaaatggac aggtagctga taagagctaa gcgcctcata
     3361 ccaagaaaag ccatggatgt agggcaccgc actgaagcca tcaatcacac ctgtctcttg
     3421 attgaccgca cctggaacgc tcatagcaat cccactgtaa tcctgttctg acaagcgttg
     3481 atctagccac gctagtaaat cctccaagtt ttcaggcgtt gaaatacttg tcttatccag
     3541 tattttccca tcaggagtca gactggcaaa cttaatccca gtccctccga tatcaatcgt
     3601 tgcaatggtc attgttttta ccataaaaag gggcgaatca gcagttagtt cttacttttt
     3661 cgcccatcct ttcttttgat gtttactttt tgaaattaaa tttcttcttt tttgatgaat
     3721 tctgtacgaa tctcttgtgg agccaatagt cctgaatgaa ctggatatag tcgctcaagt
     3781 aagtcaagaa tggtttgttg atgttctgat atgcgcacat tttcttgact catattatag
     3841 taacggagga catagccttc ttcattttcc gccactttaa aggctgttgg acaaacttgc
     3901 ggtatgctga gaacagaatg gctcaagagg ctaccagtcg caaccacgct tccttcctgt
     3961 ctagcaagct gaaggctggt aaacggtgtc tgcaaggctt tggcacgacg ataggctgag
     4021 aagcgttctt gggcttggtg gcattcaagt gcaaactcga cttcaaactc ccgcaagcat
     4081 tgtgcttctg gcgttgggaa gtagccccag tcacctagct cacctgatgc acgcaaaatg
     4141 gtcacggcaa tggtgttatc cccaaggatt tcgtattcat tcaatccctt gttggataca
     4201 gtcacccctt tttcatcgtc atacagactg acaaaagctt gttggtgttg aggattttca
     4261 gggttttccc atgaagcagc tggtttgttt ggtcgtgtca ccacctcata gatactttca
     4321 gaatcattgc ttggacgcgt gttatgagtc ttgaccaaga gacggatacg gtgatccttg
     4381 gcagtgttag taaagcgagt cttgaagcgg atttgtggat tgtcaacgaa gacagtcaac
     4441 tcagtttcca gaggaatgtt tgtcaattct tctgaccgtc cagcctcacg cttcataaac
     4501 tcgatgatac cttgttgctc ttcttctagc ttttcatccg cactgacagg cacggtcaat
     4561 tcatgtttga gcaagatttt agcatagcga tctgtgtttt ccaagacctc gtggtcctta
     4621 agctctgcaa agattggctc tgttcctttt ggttggaaat agatatactc atttccgatg
     4681 tccccacggt cttcaaagcg gataaagtct tcataggctt cgtgagttgt cttatcatag
     4741 actgtgatgt tgtcatccac actcaccgtt acgaatggtg tatcaatcac tccgttttgg
     4801 taaataccct cacggtgttc ttgttctcct tccagcaatt ggaaggttgt ccaagaaagc
     4861 ggtgctaggt gaactggaat ggtcacgcgc acttgtcgag caatacgagc ttggcggaac
     4921 ttgtcttttg gtaaatcgta ttcaaaatta gctccgaggt cttcgattgt agcctctaca
     4981 ggacgaccat ccaagtcctc cacacggtaa cttggcaaga taagagcagc catctttttg
     5041 tagccttctg ttgggtgcaa ttccttgaaa tcacaagtcg ccacatcaat cactgtgctg
     5101 acagtatcga ccttatcatg caagcctgtg ttaatgacag taaagagata gtcactttga
     5161 gccttatccg tagcaatttt acccttccac tcgttgagca aattactttt aacaaagttt
     5221 cctacttggt tgaccttggc aaaacgcgtt tccatctcgc ggtgaacttc gtccacgcta
     5281 cagccacaga tactatcatg tggcgcattc tgcaaaagtg ttttccaagc ataggtcaac
     5341 tggtccttgt ggttgtgtcc accagtgata atagtcaagg gttctaccac ttgctctagg
     5401 aggttgctat tttcttggaa ggcttgtttt aggtaaatgc gggatgaaga agtgttggca
     5461 agtgtgtacc agccatctgt ttcctgactg gtcaactcac ctgtaacagt tgataagagt
     5521 tcaggaagcg caccttctac agcttgaaca tattcatcaa aagaactatg aacaaagatt
     5581 acatccggga agagttcatt tgccacacga atggcttcgc tcagattttt ctgtacaggc
     5641 tggtggtcac agccgttcat catcaaccat tggttggtcg aagcgtaggc acgcacatct
     5701 gacaattttt gtttccagaa ggtcaaggcc tcatctttgt caactgggat ttcattccca
     5761 ttactgtacc agttagcaaa gagaatacct aaaacacgac taccatccac accctgccag
     5821 tacatttctg aaaactggga tgtaaactgc tcatcttcaa ggacttggtt gtcaaatcca
     5881 atcggcttca caccacgacc aaagaccgcc acgtgaatgc ctgatttttg aagaatttga
     5941 ggcgcttgtc ccatatttcc aaaggtatct ggaaagtagc caatctgggt tgatttaccc
     6001 catttggcag cttcttgttg accaatcaag gtattgcgga cattggcttc actggagatc
     6061 aagtagtcat cctgcaagat gtaaaaggga ccaattttaa gtttgccctc gtcaatgtag
     6121 cgttggacct tgtcgcgatt ttcagggcga atttgtaagt agtcgtcaag gacaatagtt
     6181 tgtccatcca agtggaaact cttgaactca gggtcatttt caaagagatc aaagagattg
     6241 tcaaacaatt ccaccaactg catacgatgg ctttcaaaag gcaagtacca ctcacggtcc
     6301 cagtgactat gtgagataat atgtacaaca acattttcca tgaagtaaaa cctcattcta
     6361 aatttaaatt ttaacgtttt aaatgtaaac ttgtgattct gataagaatc ggttgagcta
     6421 aagcgagccc cttagcgaat atccaagtaa tccaagacca actcacagaa catcatgtta
     6481 gcccaggaga accattcacg agagtagagg gtcggatcat ctacgtggaa gctttcgtgc
     6541 atgacacctg taccaccatc gcaggcaacc agctgatcca gcaagaattt tttctctgcc
     6601 ttatctcttg ttgtcaatcc ttggatagaa agggcgattg gccagatata gcgatagaag
     6661 gtatgagaac ttccgagacc gctagcgtat tctccttggt agaagtatgg attttcagag
     6721 ctcaaaatgg tacggcgagt agcttgatac acttcatcat cgaccgaaca gtagcccaga
     6781 tagggcgcag ctagtagact tggtacattt ggatcatcca tgatgctggc atttcctagg
     6841 ccatccactt caaaagcgta aatcttttcg cccttgctgt tggtggtgta agcgtagttt
     6901 tcgattcctt cttggatttc atcctgaaga cgcttggcat cagcaataac actctggcta
     6961 tcagctaggt ttaatgctgc gaagatttct tgcacataac ccaagactac tacagcaaac
     7021 atatttgacg gaatcaagta actatactgg caacagtcat cactcggacg aaaagctgac
     7081 caagtcatac ctgtcactgc aaagtcaggt ccaaagccat catttaccaa ggtgtcttcc
     7141 ttacggtccg tatctcggac aaaacgataa ggagagttct tgtggtcttg ttcaactgtc
     7201 catagatgga gaatttcctt agtcgctacg acaaaaatct catcaaactg actagtctcg
     7261 ccagtctctt tccagaggag ataagccaac tgcaaaggat agcaaagtga atccacctca
     7321 tacttgcgct cccagatcca gccgttaagg tctgtgtgat cagtctcgtg gtgccctttc
     7381 cagttctcct caatgttgaa ggagttagca tagggatcct tgagtaccaa ggtcatctga
     7441 cgtttgacca aacctgcaat ggtctgacgc aggagggcat ctcttttagc tacatgaagg
     7501 tagggtctga gttgggctgt cgaatctcga agccacatgg caggaatatc cccagtcaag
     7561 acaaaagttg aaccatcttc taagatttca accgtattgt ccaaggtatc ggtgtagcaa
     7621 cgctcgaaaa catccaccca ctctggatgg tccttagccc gctctgctac ttcatctagc
     7681 cattctctaa caatttcttt cgaataaatc atcgtgcaat tccctctttc aaacaagttt
     7741 cattttcagt atatagcttt tgagacagaa aatacataca caaatgatag tcatttttct
     7801 acaaaatagt tatctttaaa actccttttc taaaggccct ctttttctga tataatgtag
     7861 aaaaacagct aaaggaaaga ctatgaaacc actacttgaa accatcgata cccgctttgg
     7921 tactgctagc aagcatgcct tctctcgggg aaataccctg ccatacacag gcgtgccttt
     7981 tgggatgaat tattttgtgc cccagaccag tgaccaggac ggagcttggt tttttgatcc
     8041 gcatctgcct atctttcagg ggattcgatt aactcaccag cccagtcctt ggattgggga
     8101 ctactcttgg ctccttctga cacctgtcac cagtcaactg ggtggagaca gcctctttca
     8161 ccgccagtct tcttatgata tagataaagc ttgcttccag cctcactatt tgaagctctt
     8221 ttccctgcgc tatcaaattg aaacccagct cacaccgact tgctatggtg cttctattcg
     8281 tttgaatcaa aagcaaggca aagccctctc cctctatctt cacgcagcag atgaactgac
     8341 cgtagagcaa gtagataagc ggactctggc tctcagacaa gaaggcaaaa cagagaccaa
     8401 taaaaatcca ctgatgctct tcactgccct gcaaatgaac acggatattc ttgctatcag
     8461 ccaagaagct ggagactggc gaattgactt agcaagtagt caaaccgaga tgcaactagc
     8521 cacttctttc atctctcctt ctcaagcact acttaatcta cctcaagaag attttgatag
     8581 ctgtaaatca agtgcccaag cggattggga aaatctcctc catcgttttg acattataga
     8641 gataggagag gctgaccgaa ccttctttga ccactgtctc tacagactct tcctcttccc
     8701 acagactttt tatgaggttg atgagtcagg gcaagccatc cacatggatc tggctactgg
     8761 tactgtcaag cttggtatcc tctttagcaa caatggtttc tgggatacct tccgcaccac
     8821 cttccccctc tttgccctta tcataccgga gcactatcaa cgctttttag aaggtttcct
     8881 caatagctac cgcgatacta gtttccttcc aaaatggctg gctccagatg aacggggtat
     8941 gatgccaggt acacttttag acggtattat cgcagatagc gcctgcaagg acatggcccc
     9001 cgacctagaa ggagaactct tccaagccat gctcgaaaca gccagcaaag ccgaccctct
     9061 cggcatcaat ggccgccacg gactaaccca ataccaagaa ctaggctacc tctctaccga
     9121 ccacaacgaa agtgttagcc atactctaga ctatgcctat agtgattttt gtatcgccag
     9181 ctgtgccaaa aaactagaga acatagaaat cgctgaaacc tacaaggctg cttcacaaaa
     9241 ttaccgccag ctatttgacg ctgagacagg ttacatgcga gcacgagaca atcaaggaaa
     9301 ctttcaccct gacttctctc cttatagttg ggggcgagac tacgctgaat gctctgccat
     9361 tcaagctact ttaggcgttc tccacgacat ccctggctta atccaactta tgggtggaaa
     9421 agaaaccttt agcaactatc ttttgaaagc ctgtcaagat gctcccctct ttgaaacaac
     9481 aggctatggt tacgaaattc acgaaatgag cgagatggct actgctcctt ttggacaaat
     9541 agccatttcc aaccagccta gtttccacat tccttatctc ttccgctaca gcgattaccc
     9601 tgactacact gcccttctta tcaagacgct ccgtcagaaa gcttttcacc caagttggga
     9661 agcctatcct ggagatgaag acaatggtag tctctctgct tggtacatct ggtcagctct
     9721 cggattttat ccaacctgtc caggaaaacc aagctatgac ctcggaatcc ctctctttga
     9781 ccatctacga gtctacctcg ctaaagaaga taaatggctg gatatccata ctaaacaaaa
     9841 ccacaaccat tttaactttg tcaaagaatg ccgactggac aaaacactcg tatcaactat
     9901 tcaacaccaa gacctcttaa aagctgaaca actaactttc accctcagct ggttaccaag
     9961 tcactaataa ccaaaagaac ctttgcatcg cgcaaaggtt cttcttttat gaaacttgaa
    10021 cttgaagttg atccacaagc tgaccatcca ccgttaggtt cagatagaaa tccaaggttt
    10081 tatctcctgc gaaatacaag gttggtagcg tcagactttt ttcagtctca ccagcttgaa
    10141 acgcaagaac ttgaatctca tcctgatagg cgacaccatg gacacctgtc cccggttgaa
    10201 tcgaaatctt agcctctaaa gaggagctac tttcactacg ttcaatccta aaatgaagag
    10261 tctctccctt tgccacagct aggctttttt ctgcaaatgc tagttcctga acaacttctt
    10321 tttttgataa cccaggagtt ttataaaggg aaatcttggt cagtagaggc atagattgtg
    10381 cttcggtaat catcacgcgc accttctgtg cctctactag cggacctcgc aagaggcgct
    10441 tatgaccaac tgtgaagccc ctgccaaatt cctgccagac accatccacc tctacttgca
    10501 catggaaagc agcgattcgt tgccctagct tcaaatcttc tcttaactca attacatcaa
    10561 aagttttagg agaacctaag tcgagttcta actggatggg caaggctgca tcgtttgccc
    10621 aagagctggt ctcaaggccg tctgtcaaat ggcgacaagc aaagtctgcg gaaagagctg
    10681 gaccagatac ctcagctccc agagccaaat cttctttata gagctcattg cgataggtcg
    10741 caaattcata aagtcgttca atatcctttg catcaaagag cccagcttga ttcggcggaa
    10801 tattaagcaa gagtggagtt cctcgcccta ctgagtgaaa gtagatttcg accaactcct
    10861 cgagagactt aggatcctga tcctcatggt agaaccagcc tggacggatg gaaacatctg
    10921 cctctccgat tgaaaaaatc gtgcccgagg gatccccgtg ctgaagatag ttcagctctg
    10981 cttctgttcc tagtttatca ggattcacct tttgccacag tggatcacct gcataccctc
    11041 gttcattgcc aatccagcgg atactggtgc cttctgttga aaaaatcaag caatcgccct
    11101 gcaggtcacg agtggtttca aaccattttt taaattcata attaaccttt tgcgcaccct
    11161 ctcctctggc accatccatc caaacctcag cgaacttacc agcattccca tagttaggat
    11221 ttgataagat ttccttcaac tgagccagat aataggcatt gtagtccgct tctcggtcca
    11281 catgatagag gggactatgg gcatcccacg gtgacaggta gacccccata tccatatcaa
    11341 actctgtggc agcttgggat acttcaagga gcaagtcgcc ctttcctctc ctccaaggac
    11401 tgaccttaac cgaataatct gtgtgagctg tcggataaag gacaaagcca tcgtggtgct
    11461 tgaccaccaa aatcaacttt ttgaagcccg tttccttgag cacacgaacc cactcacgcg
    11521 catccaactg actcgggtta aagcgctcag gatcctcctg tccagtcccc cattcttggt
    11581 cataaaaggt attaggaccg aagtggataa aagctgctag ttcatctccc agataagcta
    11641 gctgagtctg acttggtaac ggtccatgcg gtttgatttt cttcatcgtt atatatctcc
    11701 ttctttagca acttctcttg ttcacaaggt tatccacagg ttgtggataa taaaccatga
    11761 tctaacagcc agctctttcc aactccaact ggtaggctca ggatttttct cctcaatatt
    11821 ccctcttcaa acagctctgt catatggttc tgctaacacc tctcagaatg ctactctcca
    11881 taattattct caggcttctt tcaggtcatt gtgtgaagac cattcactct ccagactttt
    11941 ccacagattg tgaataagtg attattctaa gctatcacct cgtcgactat aacaaaaaat
    12001 aaaaagaggg tcaataagat aattatctct tcctaaatac taagaaaaga ttctataatt
    12061 tgtacaattg aacaagaaat gcttctccaa aatctatctt caaaagaatg ttgcatcttt
    12121 ttatcctttc acacaaacat ttctctttat acagatccaa gtgataacca gatgataatt
    12181 ggacactttt tggtcatttg tatatttttt gaaaaatttt ttaaaaaaat tttatatcct
    12241 ttttatagaa gtttatgcat ttgtatctat gtattctatc ctatgttatg tataataaca
    12301 taaaattgtg ctaaacatca taatttatat tattttccga gaaattatag ccattgacat
    12361 tacctaggaa ttgcgttata acatacatgt aagcggtacc caaaatggtg ccaagtcaaa
    12421 atttttaagg aggaaaatac atgtcttctc atccaattca ggtcttctca gaaattggga
    12481 aactgaaaaa agttatgttg caccgtccag gcaaggagtt agaaaacttg ttgccggact
    12541 atcttgaaag gcttcttttt gatgatattc ctttcttgga agatgctcaa aaagaacatg
    12601 atgcatttgc ccaagctctt cgcgatgaag gaattgaggt tctctaccta gaacaactcg
    12661 ctgctgaatc attgacctct ccagaaatcc gcgatcaatt tatcgaggaa tacttagacg
    12721 aagccaacat ccgtgatcgt caaaccaagg ttgctattcg tgaattgctt cacgacatca
    12781 aggacaacca agaattggtt gaaaaaacaa tggctgggat tcaaaaagtt gaattgccag
    12841 aaattcctga cgaagctaaa gatctaactg acttagttga atcagattat ccatttgcaa
    12901 ttgacccgat gccaaacctc tatttcactc gcgacccatt tgcaacaatt ggaaacgccg
    12961 tatcgcttaa ccacatgttt gcagacactc gtaaccgtga aacactctac ggtaagtata
    13021 tcttcaaata ccacccaatc tatggcggaa aagtggattt ggtctacaac cgtgaagaag
    13081 atacgcgtat cgaaggtgga gacgagctag ttctttctaa agacgtcctt gcagtaggta
    13141 tctctcaacg tacagacgca gcttctatcg aaaaactttt ggtcaacatc ttcaagaaaa
    13201 atgttggctt caagaaagtt ttggcctttg aatttgctaa caaccgtaaa ttcatgcact
    13261 tggatactgt cttcactatg gtagactatg acaagttcac tattcaccca gaaatcgaag
    13321 gcgaccttca cgtttactca gttacttacg aaaacgaaaa acttaaaatc gttgaagaga
    13381 aaggtgactt agctgaactt cttgctcaaa accttggtgt agaaaaagtt catttgattc
    13441 gttgcggtgg tggcaatatc gtagcagctg cgcgtgaaca atggaacgac ggttctaaca
    13501 ctttgaccat cgcacctggt gtggtagttg tttatgaccg caataccgtg accaataaga
    13561 ttttggaaga atacgggctt cgcttgatta agattcgcgg aagtgaattg gttcggggcc
    13621 gtggtggacc tcgttgtatg tctatgccat ttgaacgtga agaagtgtaa tcgctgttcg
    13681 gcattcgtca atagaaaatg taaaaaatag aaagaggaaa taataaaatg acaaattcag
    13741 tattccaagg acgcagcttc ttagcagaaa aagactttac ccgtgcagag ttagaatacc
    13801 ttattggtct ttcagctcac ttgaaagatt tgaaaaaacg caatattcaa caccactacc
    13861 ttgctggcaa gaatatcgct ctcctatttg aaaaaacatc tactcgtact cgtgcagcct
    13921 ttacaactgc ggctatcgac cttggtgctc acccagaata cctcggagca aatgatattc
    13981 agttgggtaa aaaagaatct actgaagata ctgctaaagt attgggacgt atgtttgacg
    14041 ggattgaatt ccgcggattc agccaacgta tggttgaaga attggcagaa ttctcaggcg
    14101 ttccagtatg gaacggtcta actgacgaat ggcacccaac tcaaatgctc gctgactact
    14161 tgactgttca agaaaacttc ggtcgcttgg aaggcttgac attggtatac tgtggtgatg
    14221 gacgtaacaa cgttgccaac agcttgctcg taacaggtgc tatccttggt gtcaatgttc
    14281 acatcttctc accaaaagaa ctcttcccag aaaaagaaat cgttgaattg gcagaaggat
    14341 ttgctaaaga aagtggcgca catgttctca tcactgaaga tgctgatgaa gcagttaaag
    14401 atgcagatgt tctttacaca gacgtttggg tatcaatggg tgaagaagac aaattcgcag
    14461 aacgtgtagc tcttcttaaa ccttaccaag tcaatatgga cttagttaaa aaagcaggca
    14521 atgaaaactt gatcttccta cactgcttgc cagcattcca cgatactcac actgtttatg
    14581 gtaaagacgt tgctgaaaaa tttggtgtag aagaaatgga agtaacagac gaagtcttcc
    14641 gcagcaagta cgctcgccac ttcgatcaag cagaaaaccg tatgcacact atcaaagctg
    14701 ttatggctgc tacacttggt aacctttata ttcctaaagt ataattttag ataataaacc
    14761 gtctaccaac agctatgagg gctgcgacta atagctttag tccggtcctc ttttatgtaa
    14821 tggtaatcta ttatttctta taaaatatgt gaaaaatcat taaattgaaa tctaaacgca
    14881 ttctattgag tgtgataaag gagaatttat ggcaaatcgt aaaattgtag tagctttggg
    14941 aggaaatgcg attctttctt ctgacccatc agcaaaggct caacaagaag ctttagttga
    15001 aacagctaag catcttgtaa aattgattaa aaatggagat gatctgatta tcactcacgg
    15061 taatggacct caagttggga atctcttgct ccaacatttg gcatcagact ctgaaaagaa
    15121 ccctgccttc ccactcgact cacttgtcgc tatgacagaa ggtagcatcg gtttctggtt
    15181 gaaaaatgct ttgcaaaatg ctctcttgga tgaaggcatc gaaaaaaatg ttgcctctgt
    15241 tgtaacgcaa gttgtcgtag ataaaaatga tccagctttt gttaacttga gtaaaccaat
    15301 cggtcctttc tattcagaag aagaagcaaa agcagaagcc gaaaaaagcg gagcgacttt
    15361 caaggaagat gctggccgtg gctggcgtaa ggtcgttgcc tcaccaaaac ctgttgacat
    15421 caaagaaatt gaaaccatcc gtactctttt aaataatggt caagtcgtcg tagctgcagg
    15481 tggtggcggt attcccgtcg tcaaagaaaa caatggacat ttgactggtg tcgaagcggt
    15541 tattgataaa gacttcgctt cccaacgttt ggcagaattg gttgatgcag acctcttcat
    15601 cattttgaca ggtgtagatt atgtatttgt taactacaac aagccaaacc aggaaaaatt
    15661 ggaacatgtg aatgttgccc agctggaaga atatatcaaa caagatcagt ttgcaccagg
    15721 tagcatgctt ccaaaagtag aagcagctat cgcttttgtc aatggtcgtc cagaaggaaa
    15781 agcagttatt acttcccttg aaaatctagg cgccttgatt gaatctgaaa gcggaacaat
    15841 tattgaaaaa ggataagttg ttttactaat aagatgtatt ctatttctag tatctttata
    15901 tcaaattaga aattattctt gaaaacatgt acaatatttc aaaagatact agttttagac
    15961 tttaatatgg taaaacaaat ataaatagaa agcgttttct tgaatgttta tttaagaaag
    16021 tagttggttt tttacacttt gttagacatc aggaggaaaa acaaatgagt gaaaaagcta
    16081 aaaaagggtt taagatgcct tcatcttaca ccgtattatt gataatcatt gctattatgg
    16141 cagtgctaac ttggtttatc cctgcggggg cctttataga aggtatttac gaggctcagc
    16201 ctcaaaatcc acaagggatt tgggatgtcc tcatggcacc gattcgggct atgctaggta
    16261 ctcatccaga ggaaggttcg ctcattaaag aaacgagcgc agcgattgat gtagccttct
    16321 tcatccttat ggttggtggt ttccttggca ttgtcaacaa aactggtgct cttgacgtag
    16381 ggattgcctc tatcgtgaag aagtataagg gccgcgaaaa aatgttaatt ttggtactga
    16441 tgcctttgtt tgccctcggt ggtacaactt atggtatggg ggaagaaaca atggccttct
    16501 atccactcct tgtgccagtt atgatggccg ttggttttga tagcctgact ggtgttgcaa
    16561 ttattttgct cggttctcaa atcggctgtt tggcatctac tctgaatcca tttgcgacag
    16621 gtattgcttc agcgactgcg ggagttggta caggggacgg tatcgtactt cgtctgatct
    16681 tctgggttac cttgactgct cttagtactt ggtttgttta ccgttatgcg gataagattc
    16741 aaaaagatcc gactaagtca ctggtttata gtactcgcaa agaagatttg aaacacttta
    16801 acgtagaaga atcttcatct gtagaatcta cacttagcag caaacaaaaa tcagttctct
    16861 tcttatttgt gttgacattc atcttgatgg tattgagctt cattccatgg acagaccttg
    16921 gcgttaccat ttttgatgac tttaatgctt ggttgactgg tcttccagtt attggtaata
    16981 ttgtcggttc atctacttct gcactaggta cttggtactt cccagaaggc gcaatgctct
    17041 ttgcctttat gggtatcctg attggtgtta tttatggtct taaagaagat aagattatct
    17101 cttccttcat gaatggtgct gctgacttgc tcagtgttgc cttgattgta gcgattgctc
    17161 gtggtattca agttatcatg aacgacggta tgattaccga tacaatcctc aactggggta
    17221 aagaaggctt gagcggtcta tcttcacaag tctttatcgt tgtaacttat atcttctatc
    17281 tacctatgtc attcttgatc ccatcttcat ctggtcttgc cagcgcaact atgggtatca
    17341 tggctccact tggagaattt gtaaatgtcc gtcctagctt gattatcact gcttaccaat
    17401 ctgcttcagg tgtcttgaac ttgattgcac caacatctgg tattgtgatg ggagctcttg
    17461 cacttggacg tatcaacatt ggtacttggt ggaaattcat gggcaaactc gtagtcgcta
    17521 ttattgtagt gaccatcgcc cttcttctcc ttggaacctt ccttccattc ctataaaata
    17581 gtgagtgagg tgattccatg aaaatagata taacaaatca agttaaagat gaatttctta
    17641 tatcattaaa aaccttgatt tcctatcctt cagtactcaa tgaaggagaa aatggaacac
    17701 cttttggaca agcaatccaa gatgtcctag aaaaaacttt agagatttgt cgagacatag
    17761 gtttcactac ctatcttgac cctaaaggtt attacggata tgcagaaatc ggtcagggag
    17821 cagagcttct ggccattctc tgtcatttgg atgttgttcc atcaggtgat gaagcagatt
    17881 ggcagacacc gccatttgaa gcaactatca aagacggctg ggtattcgga cgtggtgtcc
    17941 aagatgataa aggcccttcg ctcgcagctc tctatgcagt aaaaagcttg ctggaccaag
    18001 gtattcagtt caaaaagcgc gtacgcttta tctttggtac cgatgaggaa accctctggc
    18061 gctgcatggc acgctacaat accatcgaag aacaggccag catgggcttt gcacctgact
    18121 catcttttcc tctgacctat gctgaaaaag ggcttctaca ggtcaaactt catggccctg
    18181 gatcggatca actagagctt gaagtaggag gcacctttaa cgttgtacca gacaaggcca
    18241 actaccaagg tcccctctat gaacaggttt gtaacgatct caaagaagct ggttatgatt
    18301 accaatccac tgaacaaacc gtaacggttc tcggagtgcc aaagcatgct aaggatgcta
    18361 gtcaaggtat caatgctgtc atccgactag ctaccattct tgctcctctc caagaacacc
    18421 ctgctctcag ctttcttgca acacaagcag gtcaagacgg cacaggaaga caaatctttg
    18481 gtgatatagc agatgaacct tctggtcacc tatcctttaa tgtcgcaggt ctcatgatca
    18541 atcatgaacg ttctgaaatc cgtattgaca ttcggactcc tgtcttagct gataaggaag
    18601 aactagtaga gttgcttaca agatgtgcac aaaactacca actccgctac gaagagtttg
    18661 actatctagc gcctctatac gtcgcaaaag acagtaaact cgttagcaca ctgatgcaaa
    18721 tctaccaaga aaagactggc gataacagtc ctgctatttc atccggtggt gccacttttg
    18781 ctcgcaccat gccaaattgt gtagccttcg gcgccttatt cccaggagcg aagcagacag
    18841 aacatcaggc aaatgaatgt gccgttctag aagatttgta ccgtgctatg gatatttatg
    18901 ccgaagccgt ctatcgactt gcaacttaat caggcaactg tttctaccaa aaaaaaatcg
    18961 accgattaat gaactgcacc ccaaaagtta gacagaataa atctaacttt tggggtgttt
    19021 tattatgaaa ttgagttatg aagataaagt tcagatctat gaactaagaa agcaaggaca
    19081 aagcttcaaa cagctttcaa aaagatttgg tgtggatgtt tctggtctaa agtcatctga
    19141 atctttgaga tgagctttat aaatcgcttt tttcagtttt tgcactggtg tttcgataaa
    19201 ctcaaacttt ttagccgtgg tattgcctga ttttatagta tattgaaact agaatagtac
    19261 acctctactt ctaaaacatt tttagaaatc gatttgactg tcctgatcga tttgtcctgt
    19321 tcttatttca ttttactata tttgagccac ttcgtcttta acggctttat tcataagctc
    19381 ttgtaatttt tctttactat caattacttc tgattttccg ttgtaattta ttgtaatagg
    19441 ttttaactta cctaatttct cgacacgctc attaatttga tcttttttga aggctgcata
    19501 tgtttttcct aagatttttt cgaaaatata tttatcagat agcggtttgc cttcttcttc
    19561 agcttggttt ttgtattgat ttgaaacata aggaacaaat ccttcatagt aacctaatgc
    19621 tcccataagt tcaaaagctt gttttctaat tcaaaccatt gcaactcaga tttcagcttt
    19681 tcagataaat cctgctcatc caaataatga cttgaaatta gtgctgaact cgtttctgta
    19741 tcctgtacag gctgatcacc cataccagca aaaaataaac tcgttcctag caagaccgaa
    19801 caagctccta ttgcatattt cctcaaagaa aaacgctgct ttctctcaaa ttgaaattct
    19861 ttcatcccat ctcccatcat tcattattac tgtatatttt gtatatcaga aatagtttgt
    19921 attcacaaat ctttctagtt attcccttat cattcctaat taagggagat aacatacaat
    19981 aatttttagt taaatgtata tcgatgtttt ttgtttttct taataaacgc aatacaaaaa
    20041 gagcctgttg ccaagctctt tgtactcaat gaaaatcaaa gagcaaacta ggaaactagc
    20101 cacaggttgc tcaaaacacc gttttgaggt agtagataag actgacgaag tcagctcaaa
    20161 acactgtttt gaggttgcag atagaactga cgaagtcagt aacatctata cggcaaggcg
    20221 acgctgacgt ggtttgaaga gattttcgaa gagtattagt ctattatttc ttctcagcgc
    20281 gaagggctga caagatttgt gttcggatat catccacacc atttggagta tttggtaaaa
    20341 agatagtttg atttccttta gaggcaaagg tattcaaggt atccaaatac tggttggtca
    20401 agaggataga catgatttgt tcttctgtca tgccaacatt ggcttccttg agttcggtga
    20461 tagactctgc caatccatcc acaatcgcct tacgttgttg ggcaatcccc acaccatgaa
    20521 ggcggtcttt ttctgcttct gcttcagctg cagtgacaat tttaatcttg tcagcttccg
    20581 ccaattcttg tgctgcgacc cgcttacgtt gcgccgcatt gatttcattc atggattgct
    20641 taacttctgc atctggttcg accttggtaa tcaaggtttt cacgataatg tagccgtaag
    20701 tggtcatttc ttctgctact tggtgttgaa cctcaagggc aatctcatct tttttctcaa
    20761 acaattcatc caaggttaat tttggaacag aagagcgaag agcatcttcg atataagatt
    20821 taatctgaga ttctggacgt atgagtttat agtaagcatc tgtcacgctc tgctcgttga
    20881 cacggtactg agtcgctaca ttcatcataa cgaacacatt gtccttggtc ttagtctcaa
    20941 ccacaatatc actttgcaac aagcgcaact gaatccgtgc tgcaatcgag tcaatcccaa
    21001 aaggcaagcg aatatgaata ccgctattag caaccttttg gtatttccca aagcgttcaa
    21061 taatcgccac cgactgctga cgaaccacat aaactgtact cagtgtgact atcaccaata
    21121 ggagcacaca aacaatcaga aaaatcatga aaaatattgc cataatggaa cctccacaag
    21181 tatttttcta gtattatagc acatttaaag aaggctgtgc cgtttttact gcgatttttc
    21241 ctgaaatgtc aataattaga ggtgaattgt cctattgtcg tccaatctct tgctaaaata
    21301 actctttata aaaggcaatc gtttcttcta aggttggcat aaatggattt cctggtgcgc
    21361 aggcatcaat caaggcattc ttagaaaggt attcaaagtc gaaatctttt tcttcaatac
    21421 caagttcagt cagtttctta ggaataccta ctgtctcaga aagcttctca atctcaacaa
    21481 tcgcataatc ggcacattct tgatctgatt taccttctac atgaagtccc aaggctttgg
    21541 caacattgcg gaaagcttct ggtacacgtt tagcattttc acgttctata actggtagca
    21601 acatggcaca gcaaacacca tgtggcaaat tatatactgc accgagttgg tgagccattg
    21661 agtgaacata accaagacca gcattattaa agctcatacc accaaggaag atggcattga
    21721 ccataccttc acgcgcttca atatcatgtc cattttctac agcacgagga agatattcct
    21781 tgataagctc aatagcacca atagacagtt tcttggttac atcataagca ccaggtgtta
    21841 ccaaagcttc aacagcgtga gtcagagcat ccataccagt agcagcagtc aggcctttag
    21901 gtttggaaag catgagttcc gggtcattaa cagagataag agcaaggcta ttcttgtcaa
    21961 ccattaccat cttaaccttg cgttcttcat cagtaatcac atagttaatg gtaatttctg
    22021 ctgatgtacc tgccgttgta ttgatagcca caactggcaa gcctttttta gcagacttat
    22081 gaagcccttc ataatcctgt ggttttccac catttgtagc catgatagaa atacaactag
    22141 ctgcatcctg tggagaaccc ccaccaagac tgatgataaa atcacagcca tgttcttgca
    22201 aagcagctac cccatctgtg acattcttac aagtagggtt tggctctaca tcgctaaaga
    22261 tgacatattc gattccttct gtatccagtg gttttaaagt cttaggtaaa atatcactgc
    22321 cttcgatgta cttatctgta accaaaagtg cctttttata gccaagttcc ttgatataag
    22381 gacccacttc atttacaaca ccttttccaa taaggttgac tgccggaaca taaaatgtag
    22441 ccatataatt ttcctcctgc gcctccgcgc tatctattta acatcattat attacttttt
    22501 gtattcgttt ttaattattt gtgaattgtt taacaaatct ttttaaaagg ataggaggga
    22561 cgtaagttca cctcctatat aaacaagttt tatttatgta gtggtcccaa caactgacat
    22621 gcacgatagt ctgctgattc tagatcttct gttccaaata aggaccaatt tttaggtcta
    22681 aagatatctt cctcaggtac attatgcata ttgacaggaa ttctcaacat agaagccaag
    22741 gtaatcaagt ctgctccaat gtgtccatat gttatggctc cgtgattagc tccccaatta
    22801 ttcatgacgt catagacaga cttgaaagca ccttttcctg tcaaacgtgg agcaaaccaa
    22861 gtagttggcc atcctggatc tgtacgatta tctaaagtat ggtgaacatc ttcaggaagt
    22921 tcaagtgtat aaccttctgc aatttgtagc actggaccaa ccccttttag aagattgaga
    22981 cgtaccattg ttactggcat atcccccttc gtcaagaaac gagttgagaa tcctcctcca
    23041 cggaagtatt cgcggtttgc tggtgggaag tctgtatttt caagcatagc ctgcacttca
    23101 ctttcatcca actcccagaa tggtttcata acaggtttgc catctcgagt agcttgccct
    23161 gtaccatcca atgtacaaga accagagttg attagatgta agaagccagc tgcagcacga
    23221 ccctctaaag tatgtcccgt tacacgttta acagcctctg gactccaata agtgcgcaca
    23281 tcagcaaaga tttgtggagt atttgttaat agataattaa agagcataga cacaccattt
    23341 agtgaatcat tctctgtcgc aaatacaaat ggttttcgaa taccattcca gtcaaactga
    23401 gtattgagga aagtttccat aaagtcccca tttgggaaat ggtctgtcca ctggcgttga
    23461 ccttggaaac cagctactaa agcatggtga ccaactgctt cttcctcaaa accaagttca
    23521 gcaagtcttg ggttaccaac cattaagtca cgtccaatca tgaacatctt aataacaaat
    23581 tcccattgtt tttctttctc ttctttagaa agaatcaaat cctcacgatt tcggtcaact
    23641 ccttctttga tatgttcttt tacccaaacc atagcacgtt caaactcttc tgggtcgtaa
    23701 ataccacggt ccatacggcg cgtgaactcc gtcatatcta ccgattcatt tcgcattcct
    23761 aagtattctt ggaagaaatc tggatttaca atagaaccgc caatccccat cgaaacacta
    23821 cccattgata ggtaagcagt gtctctcatc aagccagttg caagagctgc acgcgcataa
    23881 cgtaaaagtt tttctttgac atcttctgga atagctgtat cattagcttc ctgaacatct
    23941 ctaccataaa tcccaaaggc tggaatccct ttttgagcat gtgaagctag tacagctgca
    24001 agatagacag ctcctggacg ttctgtccca ttaaatcccc aaatagcatg aggaatatct
    24061 ggagacatat ccatagtttc actaccataa caccagcatg gtgtaactgt aattgttgcg
    24121 caaacatttg attttttaaa caactcatgg gaagctgcag cctctggaac acgaccaata
    24181 gtagatggag aaatcacgca ttccacaggt tccccatctg gatatttcaa tgtgcttgaa
    24241 atcaaatctg ccacactttt agccatgttc attgtttgca cttcaagtga ttcgcgtaca
    24301 ccttgacgac gaccatcaat agtcggacga ataccaatac gtggatgttg aatcatacta
    24361 ttttcctctt atttttctgt ttctttcata ctaccatcgc cattatattt acggtagcct
    24421 gggtgacgac ctgtaacctt ataattttct cgcattgaga atagacgttc taaagtcgga
    24481 cgagcaattt cttgctcctc aatgcccttt gtagaaagta acattcttcc gtggaaggtt
    24541 gtctttgcga ctaattctaa agtttccata cggtagtatg ctgtaattac atcgcttccg
    24601 acagtcagag ctccatgatt ttctaatagc atgacatcat gatcgggcag ataaggtgta
    24661 attgcttctg gcacttccat tgtagacgga actccaaatg gcgttatagg aattgcccct
    24721 accacaatcg cgctctcaat tagtgaataa gtatctaaag gaatgtgtgc aagagcaaat
    24781 cctgttgcaa tcggtggatg cgcgtgaaca actgaacgga catcctcacg ttcttcgtag
    24841 caccaaatgt gcattttaat ttcactagaa ggacagtaat caccttctgc ttctaaaatc
    24901 tctcctttaa gatttaactt caccagcttt tctggtgtaa taaaactttt gctgatacca
    24961 gtaggtgttg caagaatggt atcctcatct aatcgaacag atacattccc atcgttagca
    25021 gcaacccaac caagttgcca catcttatga caaacatcac aaatctgttc acgaattaat
    25081 ttttcatctt gagacataaa ctcactcctt tctaaaaatg aagttcgaat tcaagatttc
    25141 cgttactgtt aatggtaata gtaaccatat gatttttctg atcaaaattg agagatggct
    25201 gatcatagga attatttgtt cctgataatg aatgaatagt aggaagttta tctatacctc
    25261 ttaatactat ctttgtaacc cttttctctc caaactgagt atctttgata taatgttctt
    25321 caatccactt aatcgcacct ttcttggtca attgtggtag tttctttgcc tgatttgcat
    25381 cttgagcatt agaccatagt gaatctttat ttgttctaaa attatttaaa ttcactttca
    25441 atccattact tattctctca aaaataccat aggtatgagg ttcaaattca acatccattt
    25501 ctaaagaatt aaattttaat ttcccagtct gtttaacatt ctcatttacc ttgtaattat
    25561 agacaaacca tctattatct aatttctgag caaagatatc tccttcataa ttcataggat
    25621 acagcttatt taagtattct tttctagcct gagtagagct aaattctgga gaagtgattt
    25681 ccttaatctg aatacggcta ccagaaacag actctttcaa tttatctgtt tttaaaacac
    25741 ctggaatagc tggaataaca ttataacgac cagtcatgta taatggagtt tgttctctat
    25801 cagtatttac gtttacaaag aacttaccat ttcctttatt tgaatagtct ccatgtatga
    25861 atacttttgt atcctcaagt accttttctt tggatggtgc tggatgcgct attacatatc
    25921 taaaaaattc ttttattact tcgctaaaga gtaagctttc tttattattt acaccatagg
    25981 tataagctgg gtgttcaaaa ttataaacta cacctccatt aaggtaaacc cctaaagctt
    26041 cttctcctag catagactct ggttcagtca accattgtct atctccttga ctttttccga
    26101 tattaccact tgcaaacagt ttccatttac ctgtctcata ccacttccaa gtatccatca
    26161 aaccacccca ttgataagta tgatttgaaa gccaaagtcc cttcatataa ctttctgtag
    26221 ttgaatcatt tccctcagca gcaggtgtat ttttgaacat gaaaataagg ttcttccagt
    26281 acttatcaac agatttctga aatgctatct taccgttttt tccaaatgct ttttctattg
    26341 cagaaccatt attttgttca gcccatataa aatatcctcc atttttagct gatactttta
    26401 agtaatctgc cgccttattt tcaatatcat ttgcccaaat ccaataattc tctgtactga
    26461 aaataccatg caaatttgga tatttttgat acattttatc aatccagctg gtacttaacc
    26521 aatgtgccga agtataataa ggcatattac cagcagtgta aaccgtcaga ataactggaa
    26581 ttggttcatt ttttccagtc ttaggattta catatttcgc tgcttcttct aacatatgtt
    26641 cataaaaatc tctagcagct ccatctcttt tagtaagatc atctggatgt aactgtataa
    26701 cagtatatgg ttttaagtca tctggtatat tctcccactt acctgttaat gtatctcctc
    26761 cccaaaaagt atatttccct tggttaaact cttctccgtt agcatataaa ggcatcataa
    26821 gtaacggatg ttcattatta atttcacgac gtttatcaac ttctgaccaa tcattaggat
    26881 tcttaaattt accatttgcc ataaacaagg ctccacctaa aaccaattcg tcagcccatg
    26941 tatgtttccc tgaatatgat ttaagttcta ttgtctgtgt atctttggga atttcaacat
    27001 caaccagaaa tgccgatgta tcatacttaa ttccttttgg atattttgaa tctgatgagt
    27061 aaatgacttt accatccgca acaacttcaa atttttgaat atctgcgtaa tctgaattta
    27121 aatgattggc gctcctatca attccgacat aggaaataaa tcttgtaaca ttagcacccg
    27181 aaacatcata ttttatacta gacgggttgc ttgctacagt tcccaatccc ttattaaatt
    27241 cgacttcctt accgtcaatt agtaatttta ttttattatt agacccgtta ttaccaggtg
    27301 taaacggttt atctttctga actgtttttg atttatcgtc atcaccatga gtagcatcaa
    27361 cccattctaa atcagaaaga tatactcctc cattaattcc tttattaaga agatctggag
    27421 ttatagtttg agtactaaca gttttaataa gtttagcatc agcaaataca acctcatcac
    27481 cccatgtatg ttctcctgcg aatgatttta aggatatttt tttagcgttt tgtggaattg
    27541 tcacactaat aaattgtgcc tgggtattat atctgaatcc ttctggatta gttacactac
    27601 tagaatagac aacctttcca tcaatttcta tttctattct atccactact gcatggtctg
    27661 atctagaact attagcactt tgatcaattc ctatataagt ttcaaatttt tcaaaccctt
    27721 gaccgctgat atcatagctg attactgatg gagaatctgc gactgttcct attcctttat
    27781 caaaatattt aactttatca tcagaagtga gcaatgaaat cttagtatgc tctcctttat
    27841 ttcctgttgt aaatggagca tctttttgta ctgtttttgt tttatctata tcaccatgag
    27901 ttgcagaaga ccaatccata tctgaaagat atgtcatctc tttatcaatt tctttatctt
    27961 tagtaataag tttttctaag ttattccctg ttactctagc agtttcagta ctagctctgt
    28021 tattagaatt actttgaact acatctgcat aaaccaaatt acttcctaaa aaacttgtta
    28081 aaacagccgt agctattaaa atctgttttg ctattttttt actttccatt tttatttcct
    28141 caatatttac atacaacttc ttcaataaca aataattttg taagatattc tggaacacaa
    28201 agtgctaaat tacttaaact gacttttatt ccagcattca ttaattcatc tccataaaag
    28261 aactcatcaa atctagagac ggaatagcat ttatctttat ctaaaccact aaaataaact
    28321 cttgtataac ctggattcaa cttactattc aattgagcat acaataaaat cgattggcat
    28381 ttatcttttg aaacaacttg ccaactagca gaatcacaac taaaaggact gtttatccta
    28441 tagaaatccc catattgaaa caatgaacga tattttttat aaaactgaat ttgttctctc
    28501 acttgttctt tttcttctac cgacaatctc gtaacatcta attcataacc gaaagaacta
    28561 aaataagcta catttgtcct agtgtccaaa ctcgtttgtc ttccactttg ttcatttgga
    28621 gaaatagaaa catgggctgt catcattgat ggagaatatc cataagaagt tccatgctga
    28681 attttcaatc tttctatcgg gtccgtatca tcactcgtcc acgcttgcgg tgcataatac
    28741 ataagtccta aatcaaaacg tccaccacct gaagaacaag attcaaatag aactgaaggg
    28801 aacttagtta ttaaacgatc taataactga taaagaccta agatatatcg atgaccaaat
    28861 tccatctgct gttcagaatc aagttcaata ctataaatat ctgttatatg acgattcata
    28921 tcccatttga tataatccag atttgttttg attatgattt tagaaataga atcaaaaagg
    28981 taatcaacaa cttcctgtct cgtcaaatcc aacacatatt gatttcttcc tactgacttc
    29041 tctctgtcta acaaatggat agtccaatcg gcatgattct tgtacaaatc actatcaata
    29101 gaaatcattt caggctcaaa ccacaaacca aattgtaaac ctattttgtg aatttcatct
    29161 gcaagaaatc caataccttc aggaaggcga cttctatctg ttacccaatc acccagagaa
    29221 cttttgtcat ctttcctatg accaaaccaa ccatcatcca gtacaaataa ttctatccct
    29281 aaatctttag cagcctttgc taaatctaaa attttttctg tactcaagtc aaaataaaat
    29341 gtttcccaac tattgagtat tataggacga ctagcttgag aaaaattagg attaactaaa
    29401 tgatgtcgat aaaaatctga tagttgttgg ctcatctgat tcatcccttg atcagaatag
    29461 atcacaattg cttctggtgt cacaaaactt tcggcaggat ttaataaaaa acgaaattct
    29521 actggattta ttcctaccgt tactctagcg gtgtcaaaat ggtcaacttc aatcatattt
    29581 tgaaaatttc cagaatagat aaagttaaaa ccataaacct caccactatg ctctgtagtt
    29641 tccctccttg atagcataaa gaaaggattt tgctgaggac ttgatgagta tctcaagcta
    29701 tctattgctt gaatacctgg tctaagcgaa gttctatata actgacgttc cctcagccat
    29761 gctccagaaa attgaataaa gtcatattga ctatcaggta gatctagctg taagctcatt
    29821 gctttcaaaa gagtcaactt attattgcta ttatttaaaa attccgtatt tctaactaag
    29881 acattgtatt ccggaaaaat tgtgtaattt agtctaacag ttaaatctaa tatggaatct
    29941 gttaaaataa tcgttaatgt ttccacacac tgaccaatat catcaaatgt tgaaggtaga
    30001 gagttaagac gatttttccc tttttcaagt tcaaaacctt gatattttag tgtcgttatc
    30061 ctactaccat tcattccttg aacttgaaag gctggatgcc gaaaatctcc tttcccatat
    30121 gaagaatatt cattttgtat catagactgt tgaatatcct caaattcttc agaaaaagat
    30181 acttcaaatc ctcttttttc ataagccatc aattggttat aattttcctt gacatgaatc
    30241 cttttcccaa aatgtagatg ttgaagttcc ccattttcta aaattctaaa aatataacta
    30301 ctatctttca ttgccaaatg aaaaacggtc tcgtccttat taatataaat cgtcatctct
    30361 acctcacaat tttttcttta cttcttcagt atcacgatag agtacggtgc caattctatc
    30421 tcatcttctt gaatagtaaa atctccaatt actctggtaa aattctctat cgaaagattc
    30481 tctattttta ttttttgttt aatctgagca ggatttctca gagagagaat ttcagtagaa
    30541 gtcttctgat tgtgacactt ataaccataa atttcaaatt tttcaggact tcctcctatt
    30601 tttttactat attttagtgt ttgataattc tcctctatcc atttgacggc acgagcattg
    30661 gctttccagc gttcttcatc aaacatatca aaagaatagt gaaactccca aaaagcattc
    30721 cctcttgttg aaataaataa tagataagct tcaaaatctg gtattgatgc aaacatttga
    30781 tgatccatgt accaggtatt tgcactgaca gcatagattg gttcatgatt ataaatcgac
    30841 cacataggta actgtatctc acgtttttcc aaaaattctt gatactgaat atctcggtaa
    30901 gtaatcatac gattgatatc attacctgca ttctctgtaa agcctacatc ttgagatatt
    30961 tgaatccata aactattgac ccactgtaaa aaccatggac taggatttac ataagaagtc
    31021 aagtttaacc aacaatcttt tcctcctctc tcctttctta gatctatcaa cagttgaatt
    31081 aagaactcat aaaccgctgt catggtatac ataccgtgcg gtccactctt atcaggtttg
    31141 tcaggttgaa gtaaccaacc atcaattttc caatagctga tatcgaattc tttttgatat
    31201 tccaacatct ttttcttcat ttgattgaga tagttaaaat cagccacgtt tacatcattt
    31261 gaaatcaaat ttttagatcc aatatttaac tctggatgtg cttctaacca atcactcata
    31321 atgatttctg tcccattgta accacctcgg ggaccaatcc acaatcctag gcttgaacca
    31381 aatccattta caagatattt aatatttctc aaaccatttg ggaatttatg attgaattcc
    31441 caaactgatt gatagtttgt ccaaccatca tcaacaacat aagcatctaa atgaactcca
    31501 tgattttcaa atccatctcg aatctcagaa aaacttttta aaataccttc ctctgtaata
    31561 tcggtcatat ggtcatacca ggaattatac tgtttacgga aataactagg ttgagctatt
    31621 ccttcaacat attcaaaaaa tgcctcttga atctcttctt ttttataaga acatgctccc
    31681 ccaataatac aagaccacaa actcttttct tgatttacaa cagttcccaa gtaatatctt
    31741 gatacatagt gtctaccatc taccttgttt tcagacattg gaaattccat tcctaagaat
    31801 aaagaattcg cataaacagg ttgtcccaat tctacataat aaccggaaaa attcgccatt
    31861 tccttaatac aatcttgtct tttcggatag aaaatattgt cttctgtttc aaactcaaaa
    31921 ctctctacct ctacagattt aataacctca gtagatgatt ctaaaactaa ttgcttcgaa
    31981 agaacatcat ccctcgattc aaagattaaa cgtaaacgaa tggaaggaca aacaaaagaa
    32041 acctgaattc gcgtatctcc ctcttcccta acgattgctg aaaaatgatt tgaagaaagt
    32101 cttataccat tctccaatgt aatggtaaat tcttctttcg aaacattttt atcattactc
    32161 ctgcccgttt gtttacgata tcagtagtat aaaatcgacc atctccccaa aagaaattac
    32221 gtcttacatt tttattttca attttcatat aaactactct ctcaactcaa ttttgattac
    32281 gctatcaatc aagtctggta atggataggt aaaatgtgga acttctccaa actgtgcaaa
    32341 acaaattcct ttgtaggcat tggtcgtcca gctttctgaa attttcacct cacttccatc
    32401 atgaagaaag ctcattcttt ttacgttttc tttactaata ccaagaagag ctaaaggacc
    32461 tataggttgt tcaaatacat gagcataaac cgtatttcca ttacgagtat agtatcccca
    32521 atctggtttt ggtaaatttt catctccact acatccataa attgcctcac catttcgaga
    32581 catccatcga tgaaaattat ctaatatttt cttacttgaa tcattaattc ttcccaaagc
    32641 atctgggcct acattaagaa tcatatttcc gtttttacta acacattcca ctaactttct
    32701 tatcaaagtt tgactagact tatatagata atctgtagga ttataagccc aattgttatt
    32761 catagttaga caaagttccc aaggaacagg ttcaccttta aagtttcgaa taccttcgtg
    32821 aggaacaatt tgctctggac taacaaaatc tccagcgtaa gaggtaattt catctgtaac
    32881 gatacttccg aatccttcac ctgatgtttc taatctatta tctacgataa cgtttggctg
    32941 ataatgacga accatgtcta ttaattttga agctccccat ttttcaccca ccatgtcttc
    33001 ataagaataa tcaaaccata atatgtcaat ctgaccataa ccagttacaa tttctttaac
    33061 ttgattgtgc aaatactcca aataacggtc aaagttaatt ttctcatctc gataggcttc
    33121 atttcctctc attggatgat ttagatcagc atatttaggg aaatcaggat ggtgccagtc
    33181 aatcaaacta aaatataagc ctacttttaa accttcagct cgaacagcat ctacaaattc
    33241 tttaactaaa tctctacctg caggtgtatt tgttgcttta taatctgtaa attttgaatc
    33301 aaacaaacaa aacccatcat gatgtttagc cgttaaaacc atatacttca tccctgcagc
    33361 ttttgcttgt ttagcccatt ctctagggtt atattcctta ggatcaaaag ctcgaaaata
    33421 tggttcataa tcttcaatag ataatttctg atgactacga atccattccc cttttcctgg
    33481 aatagaatat aacccccaat gaatgaacat cccaaatctt gcttctctaa accactgagt
    33541 tctactattg atagtttcaa gtgtatgttt catcctttta ctgctcctcc tcctaaagct
    33601 tcaatgaagt atttacttgt aaatgcgaat agaatgattg gtggtaatac gattacaaca
    33661 atagctgaaa atagaccatt ataattagta ttaaaacttg tagtaaattg acctagtaat
    33721 gctggtactg ttaattcatt tttatcaatc accaacatag atgcccaata atattcattc
    33781 cagttattaa taaaggcaag tactgctgct gttaaaattc ctggtctagc aattggcaac
    33841 atcactttcc aaaaagtttg agcatatgtc gcaccatcaa tctctgctgc ctcctccaat
    33901 tcttttggaa taatttcaaa atagttcttt ataataaaga aactcatagc aattccacta
    33961 caagagtaga ccagaattag agcaactggg gtattataaa tccccaactc atttactaat
    34021 ctataaactg gaaaagtcat agctgttgct ggaataaata gagtagaata cagcatagaa
    34081 gtcaccaact tcttccctct aaattccatc ctagcaataa catatgaaga catggagatc
    34141 ataacaatgc taataataac tgatatagac actactttaa agctattcca aaagtaagta
    34201 aaaacatgaa gttttgtaaa aacatttata taaccttcaa gagtaaagtc aatcggtaaa
    34261 ctaatacctg gatttttcat aggatctgct tttaatgatg ataaaaaaat ccacgcaata
    34321 gggaaaatag aaattaaaat ggtaaggagc atataaccat atataagaac tttgcctttt
    34381 ttactaatac catttatatg tgtattcata atcatttccc acctttcagt ctttttcttt
    34441 ctctgaataa aatattaata caaacgataa tcaacattcc acctaagatt tgtataactc
    34501 caattgtatt tgcacgagca tattgagttc gtgagctagc cactgctaat tctcgaataa
    34561 caaaactgat actttttgtt cctgcagcac catttgtcaa aaagaatact tcgttataga
    34621 gcaaaaatcc tgaagttgct gccataattg aaacagtttt aattgtcccc ttaatcatcg
    34681 gaatcgtaat ataccactct ttcctccaac cagtaatatt gtctaaaata gcagcttctt
    34741 gaacttcttc tggaatagca aaaatttgcc caagaatcat aatggttgat gctcctgcaa
    34801 agaagatata agcgccagtc atagctacta tatttaatcc tggagtcaac agtactgaat
    34861 ctttaaacga tggattaaat agatgaataa tttggttaac aacaccatag tttggattat
    34921 agatttgaag aaaaatcaag cccatagcag cactagaaat gatacttggt acaatataaa
    34981 gattcctaga tatcttccag ccttttaatt tcttagataa tgtaattgca acagatacag
    35041 ctaaaggaac ttgaataata acaccaatta cagcccaacg aacagaatta attagagctt
    35101 ctgtaaaaaa tgggtattct ttaaaaacat acctataatt ttcaaataat ttatcaaatc
    35161 caagaaactc aggggtgttt aaatttgtat aatcccattt agcaaatgaa gttaaaaaga
    35221 ttgttactac agaataaaaa taaaatagaa agaaacaaat caacgttggc aaaagaaata
    35281 aaaagataaa tcgtcttttt tgattcttcc tattttgtag gctcataatt ttttgtgcca
    35341 taaacaaact ccttttttca actatataag taaaatcaag gtcttatcaa aagaaagcac
    35401 ggatacgtga ccctgtcctc tatgaacaca attgaacttt ctcatcaaat acgggaagga
    35461 gaaagtacta ggcaaaaaag actaatcgct agtctcgcta aagactttat tcggtctggt
    35521 atgtgtatct atctggattc cagtactact gtctacgaac tctgtcccta tctttctgaa
    35581 cttgataatt tgattatttt tacaaatggt ttacatactg cacaaaccct atctgaaact
    35641 gttaaagata gctccaaaat ctttatcaca tctggcgagg tcaaacatca atcctgttcc
    35701 gtggtcaact atgataagga aaattcttta ttagatcatt ttaatatcga tttagcattt
    35761 tgttcagcaa gaggtattga tgaccaatat gtttatgaag cttctctcag ccaagctatt
    35821 tcaaaaaaga atattattga caaagcccat gaaaccatct tactgattga tagttctaaa
    35881 ttttacaaga ctggattttt taaaattaat cccctctcca aatacacaac ctttatttct
    35941 gacaccgtgc cagaccaaaa attattagac gcagtcgaat tatttgatgg agaatgggtt
    36001 tctgatattc aatgaaaatc aaataggaag ctagtctcag cttgctcaca gtacagattt
    36061 gaaaactgat caagtcaagt cccccatgga cacggcaaga cgaagctgac atgatgtgaa
    36121 gagattttcg aagagtattc gttctgtctg ctgactgatt tacaaatatt caccacatga
    36181 cattattttc ttagcaattc taaaaacaga ggctggacaa aaactcaatt tcaggagaaa
    36241 atggagtaaa ccttcccaca ataaaacgca tagtatcaag tttttgcaca cctgatatta
    36301 tgcgtttttc tgattttaaa gactttgtcg cctagaccct atatttcaag aattaagtga
    36361 ccttgatgat ctaaatatat tgtggtatac tatttttgtc atcggttacc gattacgttc
    36421 ctatgggttt gtgagaggag gtgaaactaa tgagccttat catagagctc gctcttacta
    36481 ttatagcgga tgttatagct ggaattatct tgtatttcgt ctgcagatgg ctagatagta
    36541 aggagtagac cgactgacta gcctataaac acccgttaaa tcgctaagat acgtcaaaaa
    36601 agcccttaac tacggccata gttaggggct ttggtgttct aatgaacctt atcaattaac
    36661 tacattttag catataatct acaatagttc aagcattaag tgaggttgat gatctaaatt
    36721 tagtgtgata taatactttt gtcatcggtt accgattacg ttcctatggg ttcgtgagag
    36781 gaggtgaaac taatgagcct tataccagag cttgctctta ctattatagc agatgttata
    36841 gctggaatta tcttgtattt cgtctgcaaa tggctagatg gtaagaagta gaccgaatga
    36901 ctagcctata aacacccgtt aaatcgctaa gatacgtcaa aaaagccctt aactatggca
    36961 ctagttaggg gctttggtgt tctaacgaac cttatacact aactacattc tagcatataa
    37021 gcccagatat ttcaagagtt ttatttattt tttcaggttc ccttagttct gaaaggtcta
    37081 taatgaagtt agccatctag tatcaaaaaa ccgactagct cttatgaact agtcgatttc
    37141 tcatcaatgc gccaacattt cttgggcgat ttcttggcca gataggttat ctgggtagta
    37201 ggttggccag ttgtccattt cttcaaagag ggcttcttgg cttgtgcctc caaagaagat
    37261 atggaaatgt tctgccttaa ctggggcaac attgtggtca ctaaactgaa catacttgaa
    37321 ttgtccagcg tcagcatctg tggcttcaaa gaggaaacgc acgccacgat tgcctttctt
    37381 gtaagtcaaa attttcttac cgacatactt gtaagtgtat ttcttgcttt gtccaccttg
    37441 aacaaattcc atagtattat cagtaatgtt aatcttagtc acatctgtct gatagccttt
    37501 tgtatagtaa gccttgtact cagcctgggt catcttacca gttaacttag ccttgtagtc
    37561 aaagacttgg tcaaacgtgc cgtcttcaag gaaaggataa actgattgcc agttacctgc
    37621 atagtcactc aaggtacggt ccttgacagc tgcatcctcg aagtaaccat tttggactgt
    37681 cttggtatcc tctgcctttt caggttcgat tgctgggcct tcttggtctg ttgtttgttt
    37741 caaagccttg aggtttttct ccatcacgga aatgtagttt tctccagcct tggtgtcctc
    37801 ttctgtcaga ctttctaaag gattgaggac atcagttttg acacctgctt cttttgaaag
    37861 tgtgttagca agggcttgtg aggcattttc ttcaaaatag atataggcga ttttattttt
    37921 cttgacatac tctgtcaatt ctgccaagcg agcagctgat ggctctgcat ctggagaaag
    37981 tcctgagatt gcgacttgtt tgagtccata gtccaaggca agatagttaa aggctgcgtg
    38041 ttgagtcaca aagctctttt gttttgcttg agacaagcct tctgcgtaag ccttatccaa
    38101 ggcttgcaat ttttcgatat aggcagctgc attcttctca aaggtctctt ttttatcagg
    38161 ataatctgct gacaagctgt cgcggatgtg ctctactagt ttaatggcac gaactggtga
    38221 taaccaaaca tgggggtcaa actcatggtg atgaccttct tctccatggt catgatctcc
    38281 ctcttcttcc tcgccacctg gcaagagcaa catatcgcct gtcgccttga tggttttcac
    38341 ttttttctta tccaaggtat ctagcaattt aggtacccat gtttccatgt tttcattttc
    38401 ataaacaaag gtatctgcat cttggatttt ggcaactgcc ttggcagatg gttcgtattc
    38461 atgaggttct gtcccagcac cgattaggag ttctacatta gccgtatctc ctgcgacttg
    38521 cttggtaaat tcatagacag ggtaaaaggt tgtcacgata ttgagtttac catctgcctg
    38581 tttttgattg gaacaagcca ctaaaaacaa ggcacataga ctggctagta ataagctaat
    38641 ttttttcacg ttcgtctcct atttgataaa acgtcttact aaactgatta gtataaagac
    38701 agttacaaaa ataatggtaa tacttgcact tgcaggtgtt tctgcatagt aggaaatgta
    38761 aagtcctgct accattccca aaaagccaat cgcactggca agcagcataa ccgatttaaa
    38821 gtttttcccc agacgcaggg caatactagc tggcaagacc ataatggtcg ataccagaag
    38881 agctcctgct gcaggaatca taagggcaat agccacccct gtcaccatgt taaaaagaat
    38941 ggacatggta cgaactggca agccatccac aaaggccgta tcttcgtcaa aagttaagat
    39001 atacatagga cgaagaaaga gaaaggtcaa aatcaaaaca accgccgcaa tgacaaagag
    39061 ggaaatgacc tgttcttcac tgatagtcac gatcgaacca aagagatatt ggtccaaact
    39121 cattgaactc gagcttttac ccttgctcat gacaatcaga gaaacagcca gacctgttga
    39181 catgaggata gctgtcccga tttccataaa gctcttgtaa accgtacgga gatactccag
    39241 aaagaccgcc gcaatcaaga caatggcaat agtagaaaca gttggagaaa tccccaaaac
    39301 cagaccaaag gctacacctg aaagtgagac gtggctaagg gtatcactca tcaaactctg
    39361 acgacgcaag atgaggaagg ttcccaatac cggtgagaaa agactcatag caataaccgc
    39421 caaaaaggcg cgctgtataa agtcgtaaga taataaacta agcatggccc acctcctggc
    39481 cattctcatg aacgttgaaa caacgccatg gcgagtcttg gttacggact agatgaatat
    39541 tgcgatccgc ataatcctta acttcttcag ggtcatgggt aatcatcaaa acagccttgc
    39601 catgatgatg ggcgctgtgg tgcatgagtt cgtaaaattc atttttactt cctgcatcca
    39661 tccccgttgt tggctcgtct aggataaaca catcagggtc agaagcaaac atacgcgcaa
    39721 tcaccgctcg ctgcttttgt cccccagata gagaccccaa gcgtttgtct cgatgttccc
    39781 acatgccaac tgagtccaga ctggccttga tatgctcctc atcatgagca ttcaaacgac
    39841 ggaaccagcc ttttctcgga tagcgacccg acttgacaaa ttcatagacc gtacttggaa
    39901 aaccaacatt aaaactggca atttgttgag gaagataggc tattctcaat ttcttacctt
    39961 gcgtatttgt ctttgaaata gccacctttc caatgcgtgg ttgcagaatt ccaagactag
    40021 ccttgatgag cgtcgtctta gccgctccat tttccccagt caaggtaaca aattccccac
    40081 tatcaacact ataattgata tgttcaagaa caggctcctt atcataatag aaggacaaat
    40141 cctctaccgt aatatatctc attatttgat ttctcctact aaagcagtca aaaaccgctg
    40201 aatcactttt tgttcatttg gagtaaactg agtcgccact tgttcatagg ttaaaagtgt
    40261 atgctcatgg tgatggtggt gctcctcagc gattggacga gccaagtcag tcaactgata
    40321 aaaaatcaca cgcgcatctt tagaatcttt agatgtttcc aacatccctt ccttgaccaa
    40381 agacttaatg gccttggtaa ctgccgcctg actgacattg agacgacggg ccaattctga
    40441 atttgttaaa gattcctctg acaagagcat aaggatatgc tcctgagtat tggtcagggc
    40501 cacctcgcta gtgcaatgac ctattaggat ttcatgctga ttttccgcct gcaaaatcac
    40561 ctcattcaaa aaagcattga tatcctttgc tagctgtctc atatctgact cctttccttt
    40621 tagacttctc ttttttaaga gaaaaatact attctttgac attttgttta ccagttaatt
    40681 atatcacaag caaaaaaaga gtcaagaaaa aacgtgaaaa ctagtttcat tcttgaactc
    40741 ttctatatta tattatctat tgaaattctt tgacatctcc atcataagtc gcccaatctt
    40801 tgctgaaaaa gcgctcattc agatggtaag tcggagctgg tgtgggattg gataggaaag
    40861 gatcaactgc cttgtcaaaa gccaaccaac ccaaccagcc aaggtgaatg gtgtccttca
    40921 taaagaaagg ctccccgccg tccttagaaa aatctgctat attggtaaaa ccttgacttt
    40981 ctaactggta gcgaatcttc tgcaccgttt gttgatacat atcctctcgt agaccagcat
    41041 agtccatcca ttttttatta acaggtggaa tgataaaaat cgggtttacc ttagatttag
    41101 aaaactgtgt taaaaccaac tgcaagtcat tatactctgg cgacttgaga taggtaaagc
    41161 ttttctgaga atcctttaat ttcttcaaat ccttcttgat ctgctcatta tagaaataat
    41221 tttccattcc catctcatta ttggaagtat ttttttcagc atctgctttg acaacatctt
    41281 ctattgcttg ataagaaaac tggtctggca agatttttaa atacttagct acatgcttat
    41341 cgtagttaac atagcctcta accgaaaact gaccaaaaaa ggaggcttgg cgttcattaa
    41401 aacgagccaa taattcaatc atttcattgt ctgctgtcga caattcttct ttacttgcca
    41461 acttctgaac caggtccttc atagctacgt ttgggaactg ttgcagtaag cgagtcgctg
    41521 catattgact agcctgatcc ccagattgat gtttcagaaa actagtcaac tggtctccat
    41581 taaaatactg ctggaaggct gctggatcat agccattttt actgaaccac tgaggtgaga
    41641 taacatacac aacttgttta ttctccagct gtggtaacat ctgttgcatt ccaaaatatt
    41701 ggttaagcga tgcagctccc ccctgtccta aaagataagg acggtaggaa cgattgtatt
    41761 tctcagctaa taccgcagga tgagcaccgt caaaacgaag ccattcacta gagccaaaga
    41821 agggaacaaa acgcacattt ggatcagata gtgctctgac tttttgactt cgctccttaa
    41881 aactatcgat agtagtagcc actgctgaac gcttttcagc tcctagatta tgatgcatct
    41941 cagtaggata aaagaaaatg agcagaaaaa ccaacaaacc agcgatcaag accggtccga
    42001 agatcatcca taagcgttta agcattttgt agctccacaa taccagctat gattttatta
    42061 gctgtattcc agtcgtcacg accaaactct gttacaggga cacgaatgtc aaaacggttc
    42121 tcaatctcca caatcaactc aaccgttccc atactatcca agacacctgc atcaaaaaga
    42181 tcttcatcca tcatgtcaga aacatcttcc ataaacaact catcaataat ttcaataact
    42241 tctgatttga tatccatatt ttatttcctt ttatttttta aaccatagat tattcaagaa
    42301 tccagaaaag attaagaatg acaacatgac aacatggaaa gtgataacca tgccaagcaa
    42361 ctgaatccag cgattctcag gtagggcagc cttccctgct tttttccgtt ccttattgag
    42421 cgtttttttc ttgcgaaccc aggcatcatt gatgaccaag cctagtccat gaaagagtcc
    42481 ataggcgata tagtaccagg tcacaccatg ccaaaatccc ataatcagca tatttacaat
    42541 gtaggccatg cttgaggtta cattacgatt tttaaagact ttctttctgg ttaacaccat
    42601 caccattcgc ataaagacaa agtcacggaa ccagaaggac agactcatat gccagcgatt
    42661 ccaaaactcc tttaaatccc ttgataaaaa gggcttgtta aagttgatag ggctacggat
    42721 tcccatcaag tttgagatgg ccaaagcaaa catagaataa cctgcaaagt caaagaagag
    42781 ctccagacca aaagtataca taactgccaa ggcatagaga ttaaagaagc cacctgactg
    42841 caaggctaaa ttcttcagag gaggtagtaa ggtctctcct aaaacatgag ctaggataaa
    42901 cttatacaaa aagccccgca tgatatagcg gacagattca tccagcatat ccatcaactc
    42961 atctcgctca ggaatggcct gataattttc attaaatcgc ttaaaacgat cgattggacc
    43021 actcgagaaa gttggcatga agagaaggaa acggaggaat tcccagaggg taaaatcctt
    43081 aatcactcca tctctcagct cgatgataat cccaaccgaa cgaaatgtca ggtaagaaat
    43141 tcccaagaac ccaagcaaag actgcgttcc attgatagct ggttgcacct tgacaaagat
    43201 aatcggaagt agggacagaa aactaactaa gtagaagacc cacttgccat ccttgctttt
    43261 tcgataatgc ttgtagaaaa gcaggagcaa tatttcccag caaaggtaaa tacccaaggc
    43321 agctagttga ttggtctttc cacccaccaa catggtgaca ataaagaaga gacttaccaa
    43381 cacttcatac caggcaaagc gtttcttgaa aaagagacct ataaagatgg gcaaggttgc
    43441 agcaatcaca taaacaaaat actgaggatt gccatatggc tctaaatgag gaagctgttg
    43501 aaaaaactcc atcatctctt attcacctcg ttaatcaatc ctttgatgtc aatctttcca
    43561 tttggagtta gtggcaaact gtctcggtaa aggaatttag atggcatcat gtaggacatc
    43621 atgatgtctg tcaggtcttc cttgatggcc ttggtaatat cgatatctcg ctcaaactgc
    43681 tcacgaacac cgtcttttaa gatgacataa gccaatagat tttgtacctt gtggtccttg
    43741 ttatagcgcg gtactgcgac agcagattcg ataaagcgag acttgttgag gttttgagag
    43801 acatcttcta actcaatgcg gtaaccgtta aacttaatct ggaagtccat gcgtccgccg
    43861 tagagaagca agccctcatc tgtcatggtt cccacatcgc ctgtgtgata ggctggcaga
    43921 ccttcaaact caaagaaggc ttctgctgtt ttttcaggat tgttcatata accttttgaa
    43981 acagctggcc cagaaacaat gatttctccc tgttcgccat ttggcagttt atttccttcc
    44041 tcgtcaatga taaaggttgg agaatcagcc ttggtatagc cgattggtag gcgtttgaga
    44101 gtcgctaaca tctcgtctgt aacagcaact gctgacagag ctactgtcgc ttctgttggg
    44161 ccgtaagcat tgatgatacg ggcatttggg aaacgctcgc gcagtttttg agctgttttg
    44221 accgtcaatt cttcaccatc aaagtagaaa tgcgtgattc caggcatttt ctcactgttg
    44281 aagtattcag acaacatggc catatctgca aaggatggtg ttgatgtcca gatagcgatt
    44341 ggcaatgaaa agatagccgc aaagagttgc ttaaagtcct gagtgatgac tgaaggaaga
    44401 gtgaaaagcg taccaccaag tgccaaggtc ggtgcccaat acatgacaga caagtcaaaa
    44461 gaataaggtg gctgtgccag catttgcgga cgactcggtg tcgcaaattc cttatccgta
    44521 atcatccagt ttgtaaagct gaggagatta tcatgtgaaa tctgcactcc cttaggctta
    44581 ccagtcgtac cagaagtaaa gataatgtag taattatcat ctcccttgac tggatgcgtg
    44641 atttcatagt tgttcccttg ggcaaaggct tcttgaacct gagctagatt tatcattggt
    44701 gtagaaacct gctccaaggg aaaggctgaa atggcaataa tcaagcttgg ctctgctact
    44761 tctaaaatag ctgaaactcg ctccaaggcc gaatggctat caattggaat gtaggcatga
    44821 cctgacttag tcagcgctac aaaggttgcc aacatttcat attcttggcc accaaaaaca
    44881 accacaggag acttctcagg caagcctagt tggtcaatga ctgcagctaa actatccgaa
    44941 tcagccttta aatcgccata agtgtgttcc tgccccaaaa cattatagac aggatagcta
    45001 ggctgtgtct gagcaaaatg ctcaatggtt tcaatcatat ctgctattgg tttatttgac
    45061 acaataggga ttctccttca agttaaaatt cattatagat aaagcttcct tgaccctgac
    45121 caagatagct aaagaagtaa agcagcccta gaaagataag aaaatacaag gctgtccgac
    45181 caagaaagag gtacaattct tttctctgtt tcatcaagaa aaaccattca tttctgtaat
    45241 ttttcgctaa aataagagtg attcttacta gcttattttt ctaccattgt accactttat
    45301 atagtatctt ttcaattgtt taccgtatgt ttccaataga tttcagctta ttttaaggat
    45361 tatgcggttt ttctatatct atttcaaaag aaaaaagcct gagattttca tctcaagctc
    45421 tagcaataat agttattttc taaactaaaa aagtgagaat acaagcacgg ccaaggctgc
    45481 tccgataaca gggcctacaa caggaatcca agcgtaagac cagtctccgt ctcccttgtt
    45541 tggaattggc aagatgctgt gcatgatacg aggtccaagg tcacgagctg ggttcaaggc
    45601 ataacctgtt gtcccaccta gtgatagacc gataccgaca atcaaagttc ccactgcaaa
    45661 ggttccgata cctgcctgaa agtcgtaaag acccaaagca aagattgtca acaccaaaac
    45721 aaaagttcca aggatttcgc taatcaagtt tgatacagta tccttgatgg ctggtccagt
    45781 actgaaggtt gccaggatat tgcctgcatt ttcttctgcc tcatagtgag gtttgaattg
    45841 caaccaaacc aaaatctgac ccagcatggc ccctgcgaac tgggctaaga tataaggcaa
    45901 aacggaagcc caaggcaaac caccttttaa ggccacaccg atggtcacag ctgggtttaa
    45961 ataagctgga ctgagcttgc cagatacaaa gactgcaacc gcaactgcaa tcccccaacc
    46021 catagtaatc acaatccaac ctgagctatt gctcttggtt ttaggaagaa ccacacctgc
    46081 aacaacacca tttcctagaa gaatcaggat taaagtccct agaaattctc caaataattc
    46141 attcatcatc tttctgtctc cattaaaaag aagggacggg cgacaaggaa tgctgccctc
    46201 cacctctttt attttttctt aattttttaa ttctgctaaa tcgttgttag cgagagctgc
    46261 ttcgacatca gcacggtaag ttgctttttc ttcttctgtc cagtcataga atcgtcccat
    46321 ttcatccaaa attggctcaa cgatactatc caagctatca cgcataaaga gcatgtgatt
    46381 ggtacgacga agaaggaagt caactgggct aagagtcaac tcattgcgca ttgcatagtg
    46441 aagggacaag gtgtctgcca agctaagacc tggcgcttgt tccaagctgt gagcaagtgc
    46501 aaagaccttc ggtgcatttg aaccgtaaag atttgctagg taatgagctt ccttgctatc
    46561 caaaccacgt gaaactccaa gttgcgcaaa ggcttcgatt tctgaatcca catttgctgg
    46621 gttcaattct ccacctgaaa cagggtaagt tttagaattg atcaatttaa agctacggtc
    46681 aaattctgct ttgaggatgt caaccacgcg ctccatagct ccttcagcca tcttacggta
    46741 gtctgtgatt ttaccaccag caagagtcaa gagaccattg tcatcacggt ccaagctaga
    46801 cccacgagaa actgcagatg gatccaaatg tttctcagat gtgctacttt caagcttgct
    46861 gacagcagac tcaacatctt cacgtgtttt ttctttggag agataagatt caacagtcgc
    46921 aatcaagttg tcaaagcttt catcactgat ggtaccgtta tttccaccat tatagtcaga
    46981 ggcactgttc cctgcaatca atggacgaag acctgcccag ctgctttcga tatcatcaat
    47041 ggtgatgttg gattctggga agcggttgtt gacaatgcca agtagataat ctacatcttc
    47101 ttgagttact tttggatgct ccaaatcacc tgtgtagtct gtatcagttg taccaaagta
    47161 agtcttgttt tcacgtggga gaacaaagac catacgaccg tcacccaaac ctgtgtcgaa
    47221 gtaaactggc tgtgaaacct tgattttact tgaatccact accaagtgaa ctcccttagt
    47281 tgggcgcatt tgtgagaatt gcgttccctt attagacaaa ttacgtactt tatcactcca
    47341 aggacctgtt gtattaataa ccagacgggc cttgatttca aatacttggt ctgtcaagag
    47401 atcacgagct acaacacctg taatcttgcc actttcgtca aagaggaagc cttctgcctt
    47461 cacgtggttg gcaatgaggg caccgtcttg gttggcacgt ttgatgtttt caatcacgag
    47521 acgcgcatcg ttgttacgga agtcaagata cactccacct cctaccaagc cttccttctt
    47581 caagtttggc tggcgttcca agacttcttt cttgctcaaa accttgttcg cagttggtgt
    47641 gttgctcaca cctgctaaaa ggtcgtacaa gtccatggct actttaagac ggaagaggct
    47701 aaaggttgct ccatcttcat cgtaaactgg taagagcatt ggatctggtt ttggaatgtg
    47761 tggagcgatt tgttgaacca ctgcacgttc agaaaccgta tctgagacca cttctacgtc
    47821 gaattgtttg aggtagcgaa gacctccgtg aaccaatttt gttgaacgac tagatgttcc
    47881 ttctgcaaag tcttgcattt caatcaaacc agtctcaaga ccgctagctg ccgcctgcaa
    47941 ggctacacca gctcctgtga ttcctccacc gataatcaag aggtccaggg tgcgttcctg
    48001 cattttttta attgacaatt cacgtgtttt ctttgaaaat tccatattta cacactttct
    48061 aaataaatcg ctttattctg ccagtattag tcgtctactt ccgcaaagac ttgagttgct
    48121 ttcacagcct tcttccagcc cttgtagagt tgttccttgc gagattcatt catagatggc
    48181 tcaaagagtt ctcctgtctc gttcaagagt ttcaactcgt ccaagtcttt ccagtaccct
    48241 actgataaac ctgctaggaa ggccgctcct agagctgttg tttccaagtt tttagcacgt
    48301 gcaatatcaa tgcctaaaat atccgcctgg aactgcatga ggaagttgtt catggctgca
    48361 ccaccatcca ccttcaatac ttgaatggca gtctgagtat ccacttgcat ggtgtcgatg
    48421 atgtcacgca cttgataagc aatagattgc aaagtcgcct tgataaagtc ttctttgctt
    48481 gttccacgag tcaaaccaaa gacggaacca cgagcatttt ggttccagta tggagcgcct
    48541 agacctgtaa aggctggaac gacataaact tcatcgttgt tgtgagaatc acgagcgtat
    48601 ttttcagatt ctggtgaatt ttcaaccatg cgaagaccgt cacgaagcca ctgaatagca
    48661 cttcctgcga tgaagataga accttccaag gcataataaa ccttaccgtt gattccgtaa
    48721 ccaatggttg tcaagaggtt gttttcagac aactgcatct cttccccagt attcatgatg
    48781 atgaaagagc ctgttccata agtattctta accatacctg gctcaaaagc caactgtcca
    48841 aagagggctg cttgttggtc cccagccata cctgagattg gcacctctcc accgtagaaa
    48901 tggaatggag ctgtcttgcc gtagatttcg gagttagaac gaacttctgg aagtatagcc
    48961 ttcggaatgt taaggatttc caaaatctca tcatcccatt tgagttcttt aatgttataa
    49021 agcatggtac gagctgcatt tgagtagtca gtcacgtgag ccgcaccgtc agtcaatttc
    49081 caaaccaacc aagtatcgat agtaccaaag agcaattccc ctttttctgc tcgctcttga
    49141 gcgccttcta catgatccaa aatccaacga accttggtag cagagaagta agcatcaata
    49201 atcaaaccag tcttttcatg gaatttttcc acataacctt ggctttttag ttgctcagcc
    49261 aaaggtgctg tctggcgtga ctgccaaacg atagcattgt agataggaag tcctgttttc
    49321 ttatcccaga caaccgttgt ttcacgttgg ttggtaatcc cgattgcctc gatttgattt
    49381 ggcttgacgc cactttcgat gaaagcaccc gcaataactg actgaacaga gttccaaatt
    49441 tcattggcat tgtgctcaac ccaacctgcc tgagggaaaa tctgggtaaa ctctttttga
    49501 ctcgagctaa ccttttcccc ttttttgttg aaaatgatgg cacgagaact tgtagttccc
    49561 tggtcaatgg ccatgatgta tttttcttgt gacatgtact gtcctcctga taaagatctt
    49621 gaggtgtttc ctctttacac ttactagtat acaaaataaa gcgctttctt gtttatcaac
    49681 tttttttaat ttttaaaaaa atgtgaggag attgtgtgaa tttcacaaaa aagacctgga
    49741 ttaaccaagc cttttaagtg aataataact gacgaatccc tgccaaatct tccatatcca
    49801 agtcattttt taaataatag actggggtct gttccttctt atgaatcggg ttattggtaa
    49861 ccagcaaatc ataatgccga ctagggtcat aagcttcaat ggtaataaaa cgattgtatt
    49921 ccaaataccg tttcaaaatg gctgccatcc ttgaaaagac aagaaaacca gatgtcaaat
    49981 ccagaccaat ccgcatatgc tggccaccgt tttcagccat atattcgatt aactggagcc
    50041 attcccagag aatcttctta tctaaatctg tcccctgttg aaaagcaggt agagcatgaa
    50101 aaatctcctc tgctgtctct ttaaaatcat gttccatcag taaatatgga tgacgattct
    50161 ctaactggta cttgtagcga tcctgtaaaa tatagccctt atagagatag acttgagcac
    50221 aaagctgact gagttcatag gtgacatggt cctctgtata atcccccaat agttcctcct
    50281 tcttcatttc ttgaatcaat tgcgtcagta aatctgccaa ctgccctcca aaaccaagaa
    50341 tatattccat agtatgaaga ggaagaatgc gatgagatag gagaaaagag aagaatatca
    50401 tcatctcacc atcctcaact cctagtggaa tatgttgccc agcaaaaaag gacggaacct
    50461 ttctcagcaa acgaagatag aagatattgt caaaataccc tcgcattttc tcttctatga
    50521 cttgaaactg acaagcattg acccgaagac gttgttaact gatgtgagcc cagagaacca
    50581 agtccaattt ctgccccaca gacaaacttg caccgcagat ttcctctaaa ttggcaatct
    50641 cctgttttct ctctggtttc tgcatgtgac cttcccattc ctgactcgac cagacctttc
    50701 ggaaaagaca gaaatagaaa tagcgaatct gatgctctgg acctcgccaa cgtccatttt
    50761 ggatggataa atcaaattct gacaaaatct gatttaaacc agccaagtga cgaccaagcg
    50821 tagcctcgct aatcaccaat tcttgagcca gctgatgggc taaaaactgt tggtggtaga
    50881 gaagataaac caaaatctgg tatttaacag cactctccaa aaacaagctc cgaatatctc
    50941 tccccttggt agctgcaccg atagacagac gcagattttc atcttctgag tgaatagcca
    51001 gctctaagcc actatccaaa gccttgtcat tgagcagggt gacatatttg gttagggttg
    51061 cttttgaaaa tcctgtttct tccattacag ccttgacggt cgtctgagac tcttgtaata
    51121 gaaaggaaag gattgaaaat tgaccacact cggctttctc catcaaatct cctaaataca
    51181 tttgttaccc ctttcatttt ctaccttaag catagcataa atcttacaaa tgctaaaata
    51241 atctgtttct ctttttattt tcatgctgat ttcctggtcc attatcctga aaatcagtaa
    51301 acacacggct ccccctttgg gcatttttat gctaaaatag tagctatgga taaaattatt
    51361 aaaactatat cagaaagcgg agcctttcgt gcttttgtcc ttgatagcac tgaaaccgtc
    51421 cgcactgctc aagaaaaaca tcaaacccaa gctagctcaa ctgtagcgct tggtcgaact
    51481 cttatcgcca gccagattct cgcagccaat gaaaaaggaa ataccaaact tacagttaag
    51541 gtgttgggat ctagctctct aggtgctatt atcaccgtcg ctgataccaa ggggaacgtc
    51601 aaaggctacg ttcaaaatcc tggtgttgac atcaaaaaga ctgcgactgg tgaagtccta
    51661 gtcggacctt ttgttggaaa tggtcaattc ctcgttatca cagactacgg tactggaaat
    51721 ccttacaact ctataactcc cctcatctct ggagaaatcg gtgaagacct tgccttttac
    51781 cttactgaaa gccaacaaac gccttcagcg gtcggcctca atgtcctttt ggacgaggaa
    51841 gacaaggtca agattgcagg tggtttccta gttcaagtct tgccaggagc caagaaagaa
    51901 gagattgctc gctttgaaaa acgcatccaa gaaatgccag ctatctctac tcttctcgaa
    51961 agcgacgacc atatcgaagc cctcctcaag gctatctacg gggacgaagc ctacaagcgt
    52021 ctttctgaag aagaaatccg tttccaatgt gactgtagcc atgaacgctt tatgaacgct
    52081 cttgccagcc ttccaagctc agacttacag gaaatgaaag aggaagacca cggggtagaa
    52141 atcacttgtc aattctgcca aactacttac aactttgatg aaaaggacct ggaggaactc
    52201 attcgtgaca aatcttaata caccttttat gattggcaat gttgagattc ccaatcgtac
    52261 cgttttagcg cctatggctg gcgtgaccaa ctcagccttt cgtaccatcg caaaagagct
    52321 cggagctgga ctcgttgtaa tggaaatggt ctctgacaag ggaatccaat acaacaacga
    52381 aaaaaccctg cacatgcttc atatcgatga gggcgaaaac cctgtctcta tccaactttt
    52441 tggtagcgat gaagacagcc tagcacgcgc agcagaattc atccaagaaa acaccaagac
    52501 cgatatcgtc gatatcaaca tgggctgccc tgtcaacaaa atcgtgaaga acgaagctgg
    52561 tgctatgtgg ctcaaggatc ctgacaagat ctactctatc atcaacaagg tccagtctgt
    52621 ccttgatatc ccacttactg tcaaaatgcg taccggctgg gcggacccat ctcttgcagt
    52681 agaaaatgct ctcgctgctg aagctgcagg tgtttctgcc ctcgccatgc atggccgtac
    52741 ccgtgaacaa atgtatactg gccacgcaga ccttgagacc ctttacaagg ttgcccaagc
    52801 tctaaccaag attccattca tcgccaacgg tgatatccgt actgtccaag aagccaagca
    52861 acgcatcgaa gaagttggtg ctgacgcagt catgattggc cgagctgcca tgggaaatcc
    52921 ttacctcttc aaccaaatca accattactt tgaaacagga gaaatcctac ctgatttgac
    52981 ctttgaagac aagatgaaga tcgcctacga acacttgaaa cgattgattg acctcaaagg
    53041 agaaaacgtc gcagttcgtg aattccgcgg cctcgctcct cactatctcc gtggaacatc
    53101 tggcgctgcc aaactccgtg gagccatttc gcaagctagc accctggcag agattgaagc
    53161 cctcttgcaa ttggagaagg cttaatagtt taaaacccgt aactctctta aagagcctct
    53221 tgaatgccgc cattctttcc tcatcaaaaa aactccgtag tctctagcgc tataaatcca
    53281 gctagagatt acagagttat tttttaatct aaacttccta caagggtata ttatctactg
    53341 aaaggatatg gtatttgtag ggaatacttt aaagagttct tacaggaagt cagtattaac
    53401 tagttatatt aggtttagtt tacccattca ccattggcat tgactctata gctatctaca
    53461 gttgtgttga ctgcaagggc acctgagcca ttgacatagt accatttatc tgatactttg
    53521 aaccattggc ttgctttcat agcacctgat gcttcaagat agtaccaggt atctccatct
    53581 ttcacccaat ctgttgccat tgaaccgtta gcgtttaggt agtaccatga accattgttt
    53641 tggagccatc ctgtcaccat tgaaccatta gcgtttaggt agtaccatga gccattgttt
    53701 tggagccatc ctgtcgccat atcaccatta gcgtttagat agtaccatga accattgttt
    53761 tggagccatc ctgtcgccat agcgccatta gcgtttaggt agtaccatga accattgttt
    53821 tggagccatc ctgtcgccat tgaaccatta gcgtttaggt agtaccatga gccattgttt
    53881 tggagccatc ctgttgccat tgaaccatta gcgtttagat agtaccatga accattgttt
    53941 tggagccatc ctgtcgccat agcgccattg ctgttgaggt agtaccatga gccattgttt
    54001 tggagccatc ctgtcgccat tgaaccatca gtattgtaga agtaccacat accgttttct
    54061 tgtttccagc ctgtttttgg agtagatggt tgtgctggtt tttcagtttt tggcggttgc
    54121 tgttgagtca agcgattata ttcttcttct gatctacgag catagtcttc ttcagcttgt
    54181 tgatcagctg gtttttctgc ttttggttgt tcagctggat tctctggttt tggagctgga
    54241 gctggttttt ctggttgagg agccggcgct ggttgtggtt gttcagctgg tttttcttta
    54301 actttatctt cttctgctgc ttttcgttta gcttcttctg cttttttacg atctgtcttg
    54361 attttttcta accttgtagc ctcagctttt ttactctcaa cttccgcttt tgcttgctta
    54421 actttttcct cgtttcgaga tcccttagct tcctctttta ctagttcaag ctccgctttt
    54481 ttaacttcca catcggactc agcaatttca agttcaagcg ttttgtaagt aatggttggg
    54541 tagttacggt gatcttcttc tttttgatcc ttggcttttt tcttagcttc ttcaaccttc
    54601 ttctgagctt ctgctacctt tttttctggt ttcagggatg ggtttggaag agtttcttca
    54661 cctacgctag aatctgaaga cttcgcatca ttttcttttt tatcaggtgt tgcttgctct
    54721 ccaggaactc ctcgttttgc ccgccccttt ggtttacctt gctctttagc atctgctctt
    54781 cgtttagctt cttcttctgc ttttttacgt tctgtcttga tttcttctaa ccttgtagcc
    54841 tcagcttttt cactcttaac tttctcttct acttgcttaa ttgtgccctc gtctcgatgt
    54901 tccttagctt cctctttcaa tagttcaagc tccgcttctt taactttcac atcggactca
    54961 gcaatttcaa gttcgattgt tttgtaagta ttggttgggt agttacggaa atcttcttct
    55021 ttttgatcct cggctttttt cttagcttct tcaaccttct tctgagcttc tgctactttt
    55081 ttagtaagtt ctggttcttt tttaaactgc tcaaaagctg cgtctaactc tgctttagct
    55141 tttgacggca actcagcttt cgacttctct tctaataaaa cattaacttc taattcatac
    55201 aaatacttct ttttaatttc gctcaacttt gtgattaagc cgacattttg ggtatgtcga
    55261 tctttttcca aactttttct gaccttctcc aatatacttt gataatgcga cttgacttca
    55321 tcagcatact tcttcgatgt atcttgccca ctagatgtaa ccgtggaggt attcctacca
    55381 ccaacccctt ctgcatggac tactcctcct aagaacaagc tggcaactgc tacactagct
    55441 actccaatac taaatttacg aattgaataa tgtacttttc tttcgctttt tgatgcaaac
    55501 atgtttattt ccttctatat tttttcttta accttactat atcacttcaa tatgaactgt
    55561 atataaatcg aattttgtat ttatctcttt atgcttccat ttgggattat aacttcatgt
    55621 aatagctttt cctcttcagc tattcgtcga tacaaaataa ctgcataaac tggaaaaact
    55681 aaaacaaaag tcatataggc atgactcaac aaggtcaagc caatcaactc aggtaaaata
    55741 tttaaaaagt aattagggtg ttttactgtc ctaaacaaga tatgatctac atatttgtga
    55801 ttattgacaa gcataagctt cactgtccaa atatctccca acaagtgaat caccaacatc
    55861 aacatcagca tagaaaaaat aagcaagact aaaccaacca tgcccatgcc atcaaaaatt
    55921 gtcttgtgca ccattgcctc aaccaagcaa gagagataaa aaacaatatg agccatagtt
    55981 aatcgttttg tattctcaac tccaaattct ttcccgccat tgctaaggat tcgtttctca
    56041 ttctctatcg aacgctttaa aaaaatcaat cgaataagga atgttactaa aataatcgct
    56101 aataccatat tagtatcctt tcttttatct acacaaagaa taacacactt atgttaaccc
    56161 tatatgaact ttaataaaaa actaatctgt ctacaagcta atcttaaatt ccataccgtg
    56221 ttcataaggg agaaaactat aatccatttg atagctttct aaaatattat tcacaatgta
    56281 aagacccaaa ccggaacttt catccttatc tgtcacgatt tgagaatgat agaatatatc
    56341 aaataaatgt tctagttctt ggtcacttag aggcgcacat gtatttttga tagagagata
    56401 gccatcttgc tcggatatga ttacgcgccc atttttatct gaatatttaa ttgcattact
    56461 aatcaggttt gtcaaaacct tatccaatgc cctaagactc atgacgaccc tggtagcatc
    56521 tgtcaattga ttttcaattg taacacctat tgaatgagct aattcttgat aacgtgataa
    56581 aatatctact aaaactggct taacagtcaa ggtctcacga cactctgtcc actcttggaa
    56641 tttagaagac tccagtactt cttccaataa gtggctcatc tggtcaatct tatttatact
    56701 ctttgcaata tattttggat gatctttgta atctccaata ttatgctgca tattctctag
    56761 gataattcta agactggcta aaggggtttt caactcatgt gatgctccgc ggacaaagga
    56821 aaccttttga ttttgcaatt ttacaatttg ctcattacga ctttccaact catgaataac
    56881 cttcaacaag tgctcataca taccattaat ctgttttcca acttcaccaa cttcaccaac
    56941 ttcatctttc ctactttcat caaaacgaat attgtcatcc aaatcttgca ttttactagt
    57001 cacttctgaa atgtaaaaaa gaggattgag caagcgttta gtataaaaat aagaaaaaac
    57061 aaaggaaaaa gcaattgtaa ccaaaaatgt atatgggaga tacaaaagca aaatattctt
    57121 tgcttctttg tagacatcca ccccgtgaac aaattgcact gttacctgtt taccatctgc
    57181 tgtactaaca gacatatcta acatcacgat ataatttgat agctttccat ctttaatatc
    57241 caagtcatgc acaagaggga gtcgcttatc tacaatatct cttttaaggt gagcagatat
    57301 ggtcaaggac tttgaataag actggagtaa gcttggaatt tcatcagatg tcttagtctt
    57361 taaatactcc gtaaacactc ttgcgctctc attaaacttt tccccctcca gttgaatata
    57421 ataaaaagga aaggtcaaat aaatagctat atgaatgact agaccaacac cacctagaat
    57481 tgcaaaactt cttaaaaaag acttggttaa taatttagga ttttttatca taagctaatc
    57541 ttatacccaa catttttcac agtcacgata caatctaaag ctaatttttt gcgaagagta
    57601 cgaatataga catcaacgac cctatcacaa ggtaaatcag ctacatcttt tgaaatttct
    57661 tccaatatct gctctctact taaaacttga tttttatgct gaatcaaaca ctttagtacc
    57721 agtaattcct ttggtttgag atcaatttct tcatttttat aatgtgcttt gtaagaggta
    57781 aaatccactg ttacatcctg atatcgccaa atatcctcta tgacgtagta acgtctgata
    57841 agcgccttaa tacgcttgac aagcagtacc aaagaaaaag gttttgtcac atgatcatca
    57901 gcatagagat caaatacctg tgactgagta gtttcatctc ccagagcact caagacgatg
    57961 acaggaatat cgtgcttttg attgatttct tttaacactt caaaaccact cttcctaggc
    58021 atcattaaat ccagtaccat gagatggata gggagatctt gaaatttttc caagacctct
    58081 tgtccatcct tagccataat gacatgataa ccctcttctg tcagaaatgc tgcaattcct
    58141 tctctaatca tttcctcgtc atctgcaact aaaatgttca tctctctccc tttctactac
    58201 cagtctatca tctatgataa tggaatggat ttcatttatc cgctactttt tgtcaacaac
    58261 aacgtcaata caagaaaatc attcatcttg cagcttatac tcttcgaaaa tctcttcaaa
    58321 ccacgtcagc tctatctaca acctcaaagc aacctgcggc tagctgccta gtttgctctt
    58381 tgattttcat tgagtttcac tccactgtga cttatggtca gatgctgata cttttattct
    58441 tttatgcaat atcaaatttt aactggcctg ctttgacacc aatcttaagt gtgctgcctg
    58501 ccactaaatc tcccttaaga agaagttctg ccaacttgtc ctccacttct gtttgcaggg
    58561 ttctgcgaag tgggcgagct cccatctctg ggtcatatcc ttgatttgct aacaatttca
    58621 gagctgaagc ttgtaatttc aagtcaatgc ctttttcagc caaacttgcc actaaaggct
    58681 tgaccataat cttcaccact tcctgcatat ggtcactaga taggctatgg aagaccacct
    58741 tctcatcaat acggttgatg aattccggtc tataagcttt tttcagttct tcaaacatgc
    58801 gtttttccat attttcctgg tcaaaacgaa tatccttagc cccaaaacca acagtcttat
    58861 catcacgaag ggcagtcgca cctaggttcg atgtcataat gataatggta tttgaaaaat
    58921 cgaccttgcg tcccttgcta tctgtcaaga caccgtcatc cagaacctgc aagagaacat
    58981 taaagatatc tgggtgagcc ttctctacct catcaaagag gagaacggaa tagggtttat
    59041 tgcgaacctt ctctgtcaac tccccacctt cttcgtaacc cacatagcct ggaggagctc
    59101 catttagacg gctggctgcg aatttctcca tatactcact catatcaaag cggataaggg
    59161 ctgattcgtc atcaaagaga acttctgcca aagccttggc caactcggtc ttaccgacac
    59221 ctgtgggtcc taggaacata aaggaaccga tcggacgctt gtgactgcga attcctgact
    59281 gattacggcg aatggcacga ctaatacttg aaacagcttg atcttgaccg atgacacgtt
    59341 tatggagttc tgcttcaaga tttaaatact tcttagcatc cgtttgagtc agtttttgaa
    59401 ctgggattcc tgacaagcga ctcaaggtgg tcaaaatatc agactctgtc accaagtctt
    59461 tgtagacagg tacttcctct tcttttgcga ttagctgggc tgcctgtttc cacttgccat
    59521 ccatcagggc cttgtcagct ggactcaaat ctgaatcgtc tgcttttaca tgctttgcct
    59581 tattttgcac tgttgctgct gcttcgtcca agaggtcgat agcagagtct ggcaagtgac
    59641 gactggttaa ataacgatga gccatcttaa ccgctgtttc aaccgcttca tctgtgattt
    59701 gtacacggtg atgtttctca taagtcgcct tcaaaccttg taaaatagtc atactatctg
    59761 ccacacttgg ttcttcaatc gtcactttag cgaaacgacg agaaagagcc gcatcttttt
    59821 cgatatgttt ttgatattct tcctgagtgg tggcaccaac cgttctcaaa gttccacgcg
    59881 ccaaggctgg tttcaagata ttggccgcat ccagagtcga atcaatcccg ctaccagaac
    59941 ccatgatggt gtggagttca tcgataaaga ggatgacttg gccatcttct tcaatatcct
    60001 tgatgatatt attcatgcgt tcttcaaagt caccacggaa gcgtgtccct gcaacgacat
    60061 tcatcaaatc aagttctaac acgcgcatct tagccatttc cgcaggcacg tcaccactag
    60121 caatacgctg ggcaagacca agggccagag ctgttttccc gacaccagca tccccaacca
    60181 agacagggtt gttcttagtc ttacggctca aaatttgaat catacgtgag atttccttgt
    60241 cccgaccgat gactggttct aacttgccag aacgcgcttg ctctgtcaaa tcatgcgtat
    60301 agtcctcgag accaccacta ggagtctgcg gcatgcccat catattggcc atagaatttt
    60361 gcttgtcagc tactgtacga tggcgttggc gtaaagcctt gagatcttca cgagtccagc
    60421 ctgcccgttc ttctaaattt cgacgaagag cagcaatctt gacctgatct ttcttgtctt
    60481 cataagaaaa accagccctc tccaagatac gagtcgccaa ggcattgcca tcatgcaaaa
    60541 tcgcatagag gacgtgctct gtccctagca ccttagcatg gaccactgac gctacatact
    60601 ctgcttcgtc aaaaagaacc tgcaaacgac gggagaacgg caattccgta aaggtttcat
    60661 cctggctata gtccgtttca gtcagttcca aagccacctc ttctaaacgg tccatctcat
    60721 acggataatc atttaaagtt gcccctgcta cactataact gtgattagac atggcaatca
    60781 acaagtgcca cgactctaga taacgagctc caaaatgtcc agcaaccatg taggcacttt
    60841 cgatacattc attcaatgct tttgaatagt tcatcttact tcccttttct atctacctct
    60901 tgtatgacct gacgtagcat gtttgctcga acaactggag cttcttctcc taaaacgcga
    60961 tccaaagcta ctgattctag caaattcatc tcctgcttgg tcatcaattc ctgctcaacc
    61021 aaaagctgga gaatatcctc ataaatttct tgactgactc gctcaccaat cgagtaaagc
    61081 agctcccgga gcatttcatg atgactagaa aactcaatcc gtcctatacg aatgtagcct
    61141 ccgccaccac gcttactttc aaccaagtag cctctacttt ccgtaaagcg tgtcttgatc
    61201 acgtagttaa tctgactagg aacaacctga aaggtatctg ccaactgact ccgttgcaac
    61261 tccacgatac cagattgatc taaaatcgcc ttgatgtagg cctcaatatg atccgatgta
    61321 tttttaaatc tcataacaaa cccacctctc tctttaaacc ttgaccttgt ttgactatta
    61381 taccgaaatt ttctcatttt taaaagaaaa agggcgctgg taaaggataa tcttcaccaa
    61441 ctccctattt ttctacttat ctaagcctaa ttctgccaag atttgacgtt tgtaggcaat
    61501 cttttggact tccttgtcct catcttcaga ccaatctagt ttaatttctg aaacaatctg
    61561 cccagggcga tttttcaaga tatagatgcg gtcgctgaga ttgagggcct cctcaatact
    61621 atgcgtgatg atcagggttg ttagctgcaa ctgcttgtga atctcaagat accaagcgtg
    61681 gagttccatc tttgtcatct catccaaggc gctaaaggcc tcatctaaga gaaagagctt
    61741 gtgcccaaaa aggtaggtcc ggagtaaggc tacacgctgg cgcatcccac cgctaagttc
    61801 atgaggatac ttgtctctta cagctgtcag ctggaaggtc gcaagaattt tatccgctcg
    61861 ggaaatagct tctgccttat ccaccttttg aatcaagagg ggcagaatga tatttccaag
    61921 caccgtcttg tgctccaaga gcagatcctt ttgcaacata taactcacgc gccccttggg
    61981 attttcttca ccatcaagga caattctccc tgactgaact tctaaaatcc cagcgattag
    62041 attaaagagg gtggtctttc caacaccact tgggcctagg atggaaacca cttcgcctga
    62101 agtcacctgt aggttgatat cctctaaaat cctctcctga ccataggcat aactgacgtg
    62161 ctctagtcta atttctgtca ttatttcaca aattcgttgg tgaagccttt gtctgtcaag
    62221 tcttctttaa ggataccatt ttctttatcc catttgtaga aagcattcca gcgagctgcg
    62281 tcaaattgac cccatttttc cttgtcgctt gcgtattctt ttgacaagta tttttgagat
    62341 tcgatgacaa agtcacgttt ttccttgagt tcaggtgcat tcttgatgag aatatctgca
    62401 gcttcttctg gatgttccat ggcatattgg tagccttttt tgatggcttg gatgactttg
    62461 cgagcttctt ctttgttatc tttcagatag tcgttgtttg cgatgataac tggtgaatag
    62521 tagtcaaact ccttgacata gtctttcaag tacatgaagt tagcatctac accttgagat
    62581 ttagcaagga taccatccca accgtagtaa atccaagcag tatcaaagac cccattggca
    62641 atcggtgtga ttgagtttga gtcgttattt ggtacttttt caaccttctc aaagtctcca
    62701 ccttgagatt ctaccaaggt tttcaacata gcaagttcag ttgggtcatt ccatgtccca
    62761 tatttcttac caaccaagtc ttttggactg cttacattat cagatttacg agagatgatt
    62821 cctgatgtat tgtgttcaac aatagctgca acggcagtga ttcctgctcc tttttccaat
    62881 ttcttagcca tgtagtcttg gaaatacact gcaaatggtg cctttccgtt gataaccaag
    62941 tcagaagaac tttcttctgg tggcaatttc aaatcaacat ccactccagc ttctttgaaa
    63001 taaccttttt ccttggcaac ataaagccct gtgtggttgg tatttggtgt ccagtctagg
    63061 ataaagtcaa ccttcttaag ttctgcctct ttgttgtctt tagaagcagt tccttgacca
    63121 caggccacaa gcacaacagc tacaagagct gttacaagcg ttaaaaacac tttccatgtt
    63181 ttcttcattt tgatttcctc ttttcttttt cagaaacatt ctaattctac gaacgtttcc
    63241 atttaataac atatttttca ctaatatcga ccaacttcat acccaaaagg ctgataatcg
    63301 ataccagaat aataatagcg aacatggtat catactgaaa caatttcttg gactgaatca
    63361 tataaacacc aagcccctca aagcctccca accactcaga taccactgtt gtgataaaag
    63421 cgtaggagac actgaccctc agaccagcat aaaagtaggg caggctgact ggaattttaa
    63481 aatgccacag gatttgccaa ggcttggccc gcatcagact aaacaaggtc agcatatcct
    63541 tgtcgcaatg cctaaaaccg tccaaaatgc tgacgatgat gggaaaggtt gtcgttaaga
    63601 taatcaagac aatcttgggc aaaatcccat aacctagcca caagaccagg ataggagcta
    63661 tggcaatggt cggaatggtc tgaatgacca ccatcatagg gtaaatcagg tcattgagcc
    63721 aagtcaaact atccatgagt acagccataa gacaggcaat caaaactccc aaaatcagcc
    63781 ccagtaaagc cactctcaag gtcgcccagc tatggtgcca gagaaattct ctgtcacgaa
    63841 caaagggctg gagaatttca agaggtgtcg gcaggataaa cttggggaga agtttaagaa
    63901 aacctgctaa ctgccagatt gacaagactc cgagaaagcc caatagacta atgtgtcgtc
    63961 tcagtatact tctcaagttt ctcatcaata cttaaaatct ctcctacatt tattttgaca
    64021 ttggcaaaga cattgtctgc cccctgccct gccacttcca gcgcttcttt tagaatgcgc
    64081 ataagctcat caaactcccc ttccaagacc gtttcaaatg gtgtcactac catcgtcact
    64141 tcttgagttt gcagataagc aatgacctga tcaataacag ctatccgatc aatcccctgt
    64201 gctaggggta aaacttgcaa ggcaatgctt gctttcataa gaacctcctc ttctcgtttt
    64261 cctttttaaa aaaagaaaaa cctttaccat acatggaaaa ggtgcaaaat tagactaagt
    64321 atcgttccct ccgctggcat tacccagatc aggtgcggtc gaagtttaac acttcctctc
    64381 agactgtaca cagactccca tatattatat gtatatatga tagcgcaaaa taagaaaaat
    64441 gtcaaggaaa ctgcttacag aaaagagcag gaaatttctc ctactccaat tttctatact
    64501 cgttctccat cactgtttac tctgtagcca tccaccgtcg tattaacagc taaggcgcct
    64561 gaagagtaag aataatacca cttaccagag acctggtacc agcctgtttt cattgcccct
    64621 gaactaccca gataatacca cgagccattc tcctttaacc atcctgtctg catttcacca
    64681 gataatttca aataatacca gctagaacca tctttcagcc atcctgttga tttataacca
    64741 tttgatttga aatgatacca actaccattt attttcttcc aaccgacagt tgaactatta
    64801 ttggatccat agctagagat atttcctgat tgattctgat aattttgtga agaagtcact
    64861 ccctctagct gtatatagcg acgacttccg ttataagccg tataactcaa ccacttgtag
    64921 ccgtcttttt caagtatctg atcataatga accttctccc caggataata gtaatcaatc
    64981 acagttgcac taactagggg ttcagttttg atagcagact tggtcttaaa ataatgagtt
    65041 ccacctgttg aagaaagaac agaatgacct agaggatttt tattcacagc ctccaattga
    65101 acataacgat agcttccatt ataggcagta taactcaacc acttgtagcc gtctttttcg
    65161 agaatttgat cataatgaac cttctctcca ggataatagt aatcaatcac agttgcacta
    65221 actaggggtt cagttttaat agcagacttg gtcttaaaat aatgagttcc gcctgttgaa
    65281 gttgaggatt gactattccc aacactgcca ccatccaaat ctttaaaatg aataaatcct
    65341 gtcatcgtgt ttgcttttat aattcgttta ttataggatt ctgtataacc atagttatat
    65401 tcctcaatct caatctgatc tcccattaca tttgacaccc aggcaacatg accataagtt
    65461 cctgcagtag accaagtaat ggaaccaatc gtcggtgtat tatctacacg ataaccttcc
    65521 cgacgagcac gatgtcccca ttcattcgca tttccataag ctgccggcat ttcaaaacca
    65581 ttgacattac tcaaacgaaa ggctacaaaa gaagtacact gacgagaata catgcgccac
    65641 tgatcaattt cctggctccc atttttataa taagcaggat aatcatcccc acgcgcaatc
    65701 gatccatttc ctctggaata ggcatagaca ctatcaccag ctgctagcat caatcctact
    65761 actaaaaaag gaacaagctt tttaactgac atcttcaagt aataacttgt tcctcttgct
    65821 ataaacggta aaattttcat tcttcctcct tgaaaaataa tataaagcga tgattgcctt
    65881 cacctaaatt attcggagaa aaaagaaaaa gtgagaaaat ttctcacttt agtcaagata
    65941 atgaatcaaa ttcttttctg taagaatatc tgagtaagta aaggattcaa cgtaaacatt
    66001 aacttgttta tctccttcca catccccaaa ctccacaata aatagggatg gataaacttc
    66061 aattagctta cccaatctat ttttttggcg cttacgacca ttctccaaag tcatttctac
    66121 gacttgtccc tcatgtgcct tgatttcttc tttgattttt ttcatcttgg ctacatctgt
    66181 aaatgcatct gacatcttat gcctccctct ttgagatact tgaaaattta ttgtattctt
    66241 tttggaaaat caattccact gttccacgag ctccactacg gtttttctcg ataataactt
    66301 ccaccttatt atttgggata ccttcctctt cttcaccacc acgttcatag tagtcatcgc
    66361 gatagagaaa agctacgata tcagcgtcct gctcaataga cccagattca cgaatatcag
    66421 acaagaccgg tctcttgtcc tgacgttgtt ctacaccacg agaaagctga ctcagagcga
    66481 ttactggaac cttcaattcc ttggctagta ttttcaactg acgagaaatt tcagaaactt
    66541 cttgttgacg attttctcga ccagttcccg tgataagttg caaatagtct atcaaaatca
    66601 aaccaagatt tccagtttct tgagccaatt tacgagaacg agaacgaatc tctgtaatcc
    66661 gaatacctgg cgtatcatcg atatagatac tggcgttagc tagattaccc tgagcaatag
    66721 tatatttttg ccactcctca tctgtcaatt gccctgtacg gatagaatgt gactccacta
    66781 agccttctgc agctaacata cgatctacca agctttccgc acccatttcg agtgaaaaaa
    66841 tagcaaccgt tttgtccaac ttagtcccaa tgttctgagc gatattcaag gcaaatgctg
    66901 tcttaccaac tgctggacga gctgctaaga taatcaactc ctcctcatga agtcctgttg
    66961 tcatatgatc caaatcacga taacctgtcg caatacctgt aatatcggtc gtttgttgcg
    67021 agcgagcttc cagatttcca aagttgagat tcaacacatc tcgaatgttc ttaaacccgc
    67081 ttcgatttgc attttcactg acatcaatca gccctttttc tgcctgagca ataatttcat
    67141 cagctggttg tgacgcttcg taagcttggt tgacagactc tgtcaacttg gcaattaaac
    67201 gacgtagcat tgctttttct gcaacaatct tagcataata ctccgcatta gcagaagttg
    67261 gcacagaatt gacaatctca accaagtaag acaagccacc aatattctgt aaatcacctt
    67321 gattatcaag gatagtacga accgttgttg catctatggc atcaccacga tcggataaat
    67381 cgaccatggc ttggaaaatc aaacgatggg catacttaaa aaagtcccga gactcaatgt
    67441 attctcgcac aaaaacaagt ttactctcat caataaagat agcccctaaa acggattgct
    67501 cagctaagat atcttgaggt tgtactcgta actcttctac ttctgccatc agacttccct
    67561 tccttttaca atcttgtcaa gaaggtgtaa acttatcctt ctttcacacg aagattgatt
    67621 acacttgtga tatcttgata gattttcact ggcacatcaa tcaaaccaac cgctcgaatc
    67681 ggagcttgta cttgaatatg acgtttatca atcttaattc caaattgctt ttgcaattct
    67741 tctgcaatct tcttattggt aatagaacca aaggtacgac catctggacc aactttttca
    67801 acaaattcta caacagtttc ttctgcttca agttgtgctt taattgcttt tccttctgca
    67861 atcatctcag cgtgagcttt ttcttccgat ttttgtttac cacgaagttc acctacagct
    67921 tgagcagtcg cttctttggc tagattcttt ttgataagaa agttttgcgc ataccctgtt
    67981 ggtacttcct taatttcgcc ttttttacct tttcctttaa catctgctaa aaagattact
    68041 ttcattcttc tttctccttt tcctttattt catttaatac aatttctgtc agtttttcac
    68101 ctgcttttga caaggttaca tctttaattt gagctgctgc caaattaaag tggcctccac
    68161 cgcctaactc ttccataatc cgttgtacat tcagtttact acgacttcga gctgagatag
    68221 agataaatcc ttgtgtattc ttcgcaagaa caaaactcgc ttcaatacct gacatggcta
    68281 acatggcatc tgctgcctta ctaataacaa ctgtatcata gcatttcgtg tccttagcct
    68341 ctgctattag tacatctgaa cctaatttac gcccctgtaa aataagttca ttgacctcac
    68401 gatattcttc aaaatctgtc gcagcgattt cctggatagc aatactatca cttccgcgcg
    68461 ttctgagata gctagcaaca tcaaatgtcc gactagttac tcgcgaggtg aaatttttag
    68521 tatccaacat cataccagcc atcaaaacac ttgcttgcat acgactcaaa cgatttttct
    68581 tagaattctg gaactgaatc aattccgtta ccaactcact ggcactactt gcaccacttt
    68641 cgatataagt aatgaccgca ttatctggaa aatcctgatc ccttctatgg tggtcaataa
    68701 caatggtttg ggtaaataaa tcataaaatt cttttgataa tgttaaggct gtctttgaat
    68761 ggtctacaag aatcaacaaa gaacgattgg tcaccatccc cattgcatcc ttaacagaca
    68821 acaacttcgt aactccttct ttttctatga atgaaacagc tcgttcaata tctggagaca
    68881 tttgttcttc atcataaaga gcatagctat tttcaatcac attgctggcg aacaactgca
    68941 tacctacagc agagcccaaa gcatccatgt ctaaattttt gtgaccgact acaaaaacct
    69001 gatctacact ccgaatctta tctgaaatag ctgtcatcat agcgcgcgta cgagtccgtg
    69061 tacgcttgat tgaagcagca gacccaccac caaaataaac tggatttttc gtttcgtcgt
    69121 tttccttaac aaccacctgg tcgccaccac gtacttcagc caagttcaaa ttgagcaaag
    69181 caactttccc tatctcatca tgatttccat cgccataaga aaatcccata cttaaggtca
    69241 agggcaactg tctctgtttc gactcttctc tgaaagcatc aataacagaa aatttatcat
    69301 tcatcaagcc ctcaagcacc gtgtagtcag taaatagata aaatcgatcc atacttaccc
    69361 gacgagaaaa catcatgtat ttttctgaaa actctgatat aaaattagct acaaaactat
    69421 tgatttgact aatatctgac tcagaagttg catcctccaa atcatcataa ttatccacag
    69481 agacaatccc aatcactggt cgacttgtta ccaattcatc tgttatggct tgttccctgg
    69541 atacatctac aaaatacaaa acaccggaag aagcatccat atgaacagca taacgcttct
    69601 caccaagctt ggcataagta gacggatttc ctactgaagc cttaataatc gtttgaacag
    69661 cttctaaatc aaaatcacca tcttccttgg tcaaaatcaa ttcagcatag ggattaaacc
    69721 actcaacctc tccagaagat aaattcaatt tcataacacc tacaggcatc tgttccaata
    69781 gagatgtcaa actttcttcc gcttggtggt ttacatactg tatctgttct acatcactcc
    69841 ttgtataatg cactctcagt ttcttaaata aaaaaacata gcctcctaca aaaagaaaca
    69901 aaattaaaac cgtcaacaga ttattattaa caaaaataat gaaagtggat aagactccaa
    69961 acgcaatcaa tcctactaga ataggaaaaa ttggacttac ataaaatttt ttcattcaaa
    70021 acctcttggc acccattata ccataatacc cctcaaaaag cgacttttta aaagtgtaat
    70081 cagtaattct atcaattata agaaaaaggt agtttacaat tcagtaaacc tacctttaca
    70141 catattgaaa ttaagattct ttaacctcta acaaaccaat ttcgccatcc tcacgacgat
    70201 aaatcacatt ggttgtctga tcttcaacat ccacatagat aaagaaatca tgccccaata
    70261 aatccatttg tagaattgct tcttccaaat ccattggttt taaatcaatt tgttttgaac
    70321 gaacaacttt agactggaca acatttgaat cttccaccaa agcatctgta aataattgac
    70381 cagttgctac cttattttta tttttacgct cgatttttgt tttattttta cgaatctgac
    70441 gttcaatttt atcagttaca aggtcaattg aaccatacat atcttgagat acatcttctg
    70501 cgcggagagt aatagatcca agcggaatcg ttacttccac tttagccgtt ttttcacgat
    70561 aaacttttaa gttaattcgg gcatccaact cttgttctgg ttggaagtac ttttcgatct
    70621 tttcgagttt agaaactaca taatcacgaa ttgcttctgt tacttctagg ttttcaccac
    70681 ggatactata tttaatcata tgagtacctt ctttctaaac atttttgttt ttatgatttt
    70741 attataacgc tttcattcta tttttgcaaa ttttttcctc atcttacaag ggaaaatgtt
    70801 tttacatcct tagcaccagc ttcttccaac agtttcttaa cacgatttat agttgctcct
    70861 gtagtataga tatcatctat aagtaggatt tttttaggaa tagtgactcc acttttaata
    70921 aagaaaggaa gttctgtccc caagcgctct gaacgatttt tagaagaact ggctctctct
    70981 tctcttttct ctaataaatc cagatactca aaacctgctg cctctaccaa gccctcaacc
    71041 tgattaaatc ctctattagc atatctatca ggacttaggg gaattacaac aaattgatac
    71101 tctttgtact ttttcaactc ctcacttaaa aatgaagcga aaacttttct taacaggaag
    71161 tctccatcaa acttataccg actgaaaaaa tccttcatag cttgattgta agtaaaaatc
    71221 gctctatgac tgactccaac tccttcttta caccaaagtt gacaatcttg acactttgtt
    71281 gacaactctg ttttcataca atttggacag ttctcttccc caattctttc aaaagtagaa
    71341 tcacagtctg aacaaagaca agagtcatca ttcctcagaa gtaagagact actaaaagtt
    71401 aaaacagtct tcatagtctg cccacataac aagcacttca tagaccagcc tccttattca
    71461 tcatctgaat ttccttaatc gccttcttga ttgaagcatt taacccatca tggaagaaaa
    71521 gcaaatctcc tgtcggtcta tccatgcttc gtccaactcg tccaccaatc tgaatcaaac
    71581 tagacttggt aaacaaacga tgattggcct ctactacgaa aacatccaca caagggaagg
    71641 taactccacg ctccaagatt gtcgtactga taagtattgt cagttctcca tctcgaaaag
    71701 cttgtacttg ctctaatcga tcctctgtta cagaagatac aaagccaatt ttctcatttg
    71761 gaaattgctc ctgtaaaatt tcttctaact gctccccttt cttaatttct gaagcaaaaa
    71821 tgagtaacgg ataagctgtc tttctctgct tctcaatata ggactttaac tttggtgaca
    71881 aacgattctt gtctaagtag cgattaaaat ccgataacca aattggtttt ggaataatca
    71941 acggatttcc atgaaaccgt ctcggtaaat tcagtctttt tagttctcct aaacggacct
    72001 ttttatctaa ctcattggtc gaagtcgctg ttaaaaagat tctcaatcca ttctccttta
    72061 cactattctt gacagcgtgg taaagcattg gattatcaac ataaggaaaa gcatctactt
    72121 catccactat cagcaaatca aaagcttgat aaaacttcaa taactgatgg gttgttgcaa
    72181 caactagtgg tgttcgaaaa taaggttccg attctccatg tagcaaagct atcccgcaag
    72241 aaaaatcctg ttgcaggcgc ttgtacagct ccaaacaaac atctatgcga ggactagcca
    72301 aacacactgc accacccgca ttgatcactt tagccactac ttgataaatc atttctgtct
    72361 ttccagctcc tgttaccgca tgaactaagg ttggcttttg cttgtctact gcttgaagca
    72421 gtccctctga caccttctct tgaaaaggag ttaattggcc gcgccatttg agaacatctt
    72481 gcttcggaaa atcctcctgc ggaaaatagt ataaagtttg atcacttctg actcgcttca
    72541 tcagcaagca ctctcgacaa tagtaagcac cgatgggcaa ataccattct tctagaatag
    72601 tactattaca acgttgacag aaaagtttcc ccttctcctt tctcattgct ggaagtttct
    72661 ccgccaactg acgttcttct tctgttaatt cattctcagt aaataaacga ccgagataat
    72721 ctaaatttac tttcatactt ctttattcgt aaaaactagc actttagatg attttttagt
    72781 acaattaaat catggaattt agaacaatta aagaggacga ccaagtccaa gaagaaatca
    72841 aaaaatctcg ctttatctgc catgccaagc gtgtttatag cgaagaagag gctcgtgact
    72901 tcattactgc catcaaaaaa gaacactaca aaacgacaca taactgctct gcctttatta
    72961 ttggagaacg tagtgaaatt aaacgtacaa gtgatgatgg tgagcctagt ggtactgctg
    73021 gtgttcccat gcttggggta ctagaaaatc acaatctcac caatgtctgt gtggtcgtga
    73081 cacgctactt tggtggtatt aaactaggcg ctggaggact aattcgtgct tacgccggca
    73141 gtgtcgcctt agctgtcaaa gaaattggta ttattgaaat aaaagaacag gctggcattg
    73201 ctattcaaat gtcttatgct cagtaccaag agtacagtaa cttccttaaa gaacatgatc
    73261 tcatggagct ggatacaaac tttacagatc aagtcgatac gatgatttat gttgataaag
    73321 aagaaaaaga aactattaaa gctgcacttg tggagttttt taatggaaaa gtcactttaa
    73381 ctgaccaagg tttacgagag gttgaagttc ctgtaaactt agtgtaaaca atgaataata
    73441 cagcgtttcg ttgacattct cacaactact ttagcgagca aaataaaaag atgcgtacca
    73501 aaatatacta gaaaatgaag caattcaaac gaaacctgat atcgttttcc ttcacaccta
    73561 tttactagaa ttagctgaac gcaatcactt gaaaattaat gactttgatc tatgatatat
    73621 agaaatccta tcgcttcgat aggatttcta tattttacaa atggtatgga tagcgttata
    73681 ctaaagatat cttatacaaa gaggtattca tatgtctatt tataacaaca ttactgaatt
    73741 aatcggtcaa acaccgattg ttaaacttaa caacatcgtg ccagaaggtg ctgcagacgt
    73801 ctatataaag cttgaagcat ttaatcctgg ttcatctgta aaagaccgta ttgcccttag
    73861 catgattgaa aaagctgaac aagatggtat tctgaaacct ggttctacta ttgttgaagc
    73921 aacaagtgga aacactggta ttggactttc atgggtaggt gctgctaaag ggtataaagt
    73981 cgtcatcgtt atgcctgaaa ctatgagtgt agaacgacgt aaaattatcc aagcttatgg
    74041 tgctgaactc gtcctaactc ctggtagcga gggaatgaaa ggtgctattg ctaaggctca
    74101 agaaatcgct gctgaacgtg atggtttcct tcctcttcaa tttgacaatc cagctaatcc
    74161 agaagtacac gaaagaacaa caggagctga gatactagct gctttcggta aagatggatt
    74221 agatgccttt gttgctggag taggtaccgg tggaacgatt tctggtgttt ctcatgcact
    74281 caaatcagaa aattctaaca ttcaagtttt tgcagtagaa gcagatgaat ctgctattct
    74341 atctggtgaa aaacctggtc ctcacaaaat tcaaggtatc tcagctggat ttattcctga
    74401 tacacttgat actaaagcct atgatggtat cgttcgtgta acatcagatg acgctcttgc
    74461 actcggacgt gaaattggtg gaaaagaagg cttccttgta gggatttcct cagctgcagc
    74521 tatctacgga gccatcgagg ttgccaaaaa attaggtaca ggtaaaaaag tccttgccct
    74581 agcaccagat aacggtgaac gttatctctc tacagcactt tatgaattgt aaccgtccaa
    74641 taacgaagta tattgaaaaa tctccagact agagaactca cggatagttc ctaatctgga
    74701 gatttcttat ttgcactttt cttgtacaac tttagtccat ggtaaataag cctctaaaac
    74761 ctctttgttt acgagagttt ccacgtttgg aagacattct agaagatagg atagatattt
    74821 ctcactattt ataatggatt gaaataagat atgaacaaat cgattaggac atgatggtaa
    74881 agcgtaatcc cttgtttctc agctttccca gacaaaaaag tccaatagta agtcagctga
    74941 ctatcactct ctagcaccct ataagaagtt tcatccgcat gaagtaagga ctgcgtcaat
    75001 agtctctctc gcaagaggtt ataaaggggc tccaaatagt attgactcgc cttgatatgc
    75061 caattagcaa tttccttacg tgtgattggt aaacccatct tagcccaatc ttcttcttgg
    75121 cgataattgg gtaccttcag attaaacttc tgatggatgg tgtgagcgat aatagaagct
    75181 gagccaaggc tatgcgccaa aggggcttta ggaataggag ctttcacaag cttatccaga
    75241 tgattatctt ttactcgtta tggacaatgc tatatggcat aaatcaagta ccttaaagat
    75301 tccgactaat attggtttta cctttattcc tccatacaca ccagagatga accccattga
    75361 acaagtgtgg aaagagattc gtaaacgtgg atttaagaat aaagcctttc aaactttgga
    75421 agatgtcatg aatcaactcc aagatgttat acaaggactg gagaaggagg tgataaagtc
    75481 catcgttaat cggagatgga ctagaatgct ttttgaaaac agatgagtat aaaaagaaag
    75541 tcctcatttc aatagaaatc acgactttct gatggattta tagtaaaatg aaataagaac
    75601 aggacaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttaaaa gcagaggtgt
    75661 actattctag tttcaatcta ctatattttt ggagtgatag aaaagccctt cataagctag
    75721 tctacttgtt caggtgcgag agctttgaca tccttttctg tacttagcca agtcagtttt
    75781 ccgttctcaa agcgtttata tagtagccaa aatccttgac catcccagta aagggcttta
    75841 aagcggtctt tacgtccacc acaaaagaga aagacttgac cggagaaaga atccaattca
    75901 aagtgggttt taactacata ggctaatgag tctattccct gcctcatatc tgtcttgcca
    75961 caaacaaggt gaacttgacc taaatcactt agttgaatta tcatagtaca atacctttcc
    76021 tccgataatt attttttatc tagtatactg gaagttgggg aattaggata gataccttgt
    76081 tatgacgcgc ttactatgaa ttttaagtat agtctcctaa atgcacttag cccttattat
    76141 agggcttttt gttttaatta ttctaatcga gtgagactgg ggaaaaaaca atttcaggaa
    76201 aaatctaagc cctatacaaa aaaggaagca atttgcttcc tttctattat tagttattca
    76261 aggctgctgc cattgtagct gcaacttcag cttcgaagtc gtttgcagct ttctcgatac
    76321 cttcaccaac ttcaaagcga gcaaactcaa ctaccgaagc gttaactgat tcaaggtatg
    76381 cttcaactgt cttgctgtca tccatgatgt aaacttgtgc aagaagtgtg taagcttggt
    76441 caactttagt gttatcaagc atgaagcgat ccattttacc tggaataatt ttgtcccaga
    76501 ttttttctgg tttgccttct gcagccaatt cagctttgat gtcagcttca gcttgagcaa
    76561 taacatcatc agttaattga gcttttgatc catacttcaa gtgtggaaga gctggtttat
    76621 taaccattgc acggctttcg ttgtcttggt cgataacgtg attcaattgt gccaactcat
    76681 ctttaacgaa ttgctcatcc aattctttgt aagaaagaac tgttggtttc atcgctgcga
    76741 tgtgcattga caattgttta gcaagtgctt cgtctccacc ttcaacaact gaaataacac
    76801 cgatacgtcc accgttatgt tggtatgctc caaagtgttg tgcgtctgtt ttttcaatca
    76861 atgcaaagcg acggaatgag attttctctc cgatagttgc tgttgcagat acgtatgcag
    76921 cttcaagagt ttcacctgaa ggcattatca aagcaagagc ttcttcattg ttagcaggtt
    76981 ttccttcagc aatgacttta gctgtagtat ttaccaattc aacgaattga gcgttttttg
    77041 caacgaagtc agtttcagcg tttacttcaa taactgctgc aacattaccg ttaacataaa
    77101 caccagtcaa accttctgca gcaacacggt cagctttctt agctgcctta gccatacctt
    77161 tttcacgaag caattcaatc gctttttcga tgtcaccgtc tgtttctaca agcgcttttt
    77221 tagcgtccat aacaccggca ccagattttt cacgcaactc ttttacaagt ttagctgtaa
    77281 tttctgccat tttaattctc ctatattttt tgaaaatagg agagccgggc taagccccgc
    77341 cctcctaggt aattactatt tgtataaatt aagcgttgtc accttctaca acttcaacga
    77401 tttcttcaat tgaatctgct tgagtttctg aagctgcaaa ttctgcttca actgctactg
    77461 catcctcacc ttgacgtcct tcgataatag cgtcagccaa tttagctgtg atcaatttaa
    77521 cagcacggat agcgtcatcg ttagctggga tgattacatc gatatcatct ggatcagtat
    77581 tggtgtcaac catcgctaca actgggattc ccaatttttt agcttcttta acagcgattt
    77641 gctctttatg tgggtcaact acgtacatca catctgggat acgaggcata tcttcgatac
    77701 cacccaagaa tttttcaaga cgcgcacgtt gtttgttaag aagtgcaact tctttcttag
    77761 gaagaacttc gaaagttcca tcttcttcca tacgtttaat ttctttcaaa cgagcgatac
    77821 gtttttggat tgttccccag tttgtaagag ttccacccaa ccaacggtgg ttgatgaagt
    77881 attgacctga acgtactgct tcttcagcaa ctgcatcagc tgcttgtttc ttagtaccaa
    77941 cgaacaatac aactgcatcg ttagctgctg catcacgcat gaagtcgtat gcttggtcag
    78001 cgtattttac agtttgttgc aagtcgataa cgtggattcc gttacgttca gtaaagatgt
    78061 acttagccat cttaggattc cagcgacgag tttggtgacc aaagtgtaca ccagcctcaa
    78121 gaagttgttt cattgaaatt actgccatga gtatttctcc tttttgtttt tttcctcttc
    78181 ttgacttcaa ctcgcaaaac gacccaaggg caactgcttc acaattcatc aagaatgagt
    78241 attatcgttc acacgacaat tttcattcta ccatactttt ccaatatttt caagctattt
    78301 tgatataatt tttaataggg attgtcacgg taaaacctga aaagagggct ctattcgagt
    78361 ccctctgtaa attaatctgc ataaatatat gtaacaaaac cttcagaagt tgttgttgga
    78421 ttgaaccatc cacggtgatt tccaattgta cgattacctg cataatttga ttctgatact
    78481 tggatacgtg ttgttgattc aacagctgta acaaccgcta cgtgaccata tccaccatca
    78541 ttccaacatg caattgctcc aacttgaggt gttgaacctg tacggaaacc tgctgctgct
    78601 gcacttgtag cccactgtgc tccattaccc cagtagtctc cagcccaagg tgccaatgtt
    78661 tttactcccc atgtacattc tccaattgga taacttgaag cgtttgtact gtatgttgga
    78721 cgaacttttg cacggacagg tgctgctgca gattcagata ctgcttgcac ttgagctgtt
    78781 aagttagtgt ttgctgaagc aagtactgat tgttgttggc tagctcgttt ttctttataa
    78841 gctgcttctg ctaccgcagc tgcacgagcc tctgcctcag ctgctgcttt ttgctctaat
    78901 agacttgctt tttccccttc agctgtcgct ttctcagcag caagacttaa ttcagcagct
    78961 tttagttctg cctgtttcgt agtcaatgct tgagcatcat cagccaattt ttgttgatta
    79021 gcaattacag tattgatagc atcattattt gctacttgtt tttcagaaat agctttttta
    79081 tctgcctttt gttgttctaa cattttgttg tttgcagata cgatttcact cattgcagca
    79141 acacgtgaaa tagcttctgt aattgatttt gagtttacaa tggtattgat atagctagtt
    79201 acggctccat ttgtttgagc actacgagct tgtttttcca acgattggtt acgagaaaca
    79261 atgtttttag aaagttctgt aatctcaccc tcgagtttct tagattctgc ttgtaatcta
    79321 tcattttcag cttgcaagtt agactgctca gcttgaatag ctgatacttg ctcctgaatt
    79381 tggtcaactt gtttttgggc ttcttgttgt tgtgctgtta agttactaat tttattatct
    79441 tgagcagcaa ttttgtcatc agtcgtttct gcatgcgcag ttgttaaaac agctacttga
    79501 gaaaccatta ctgtacttaa taaaagtgac gctaagattt ttttcttcat attacgtaga
    79561 tactccttct tttaaagaca atactagtat accaaaaaaa ggcctaataa atattacgcc
    79621 tttgttacat ttatatgtcg ttcttataga taatattttt caaaaataaa ttgaaaaaca
    79681 gtaatccata aaaaatttaa aatcatcgtc ggtaccaagc tatagactat aaaaatcgac
    79741 atgctatcta ctgtcaaccc taccataaaa gccaaaagat aactacccat ttcaaacagg
    79801 aatgtcagca caatcatagc tagcattctt gtccaacgat tcaacaaaat aacactattc
    79861 aatttatgaa ggaaggctcc caataagata aataagagag ttgtaatccc tattagatgg
    79921 aaaaagtaaa catcataaac caagcctata acaaaacaat agactaggta gagatactct
    79981 gatacttcta tcgtctcaaa taagagaaat agaaaaagaa aatgactagc caaatgtaca
    80041 tgggggaaaa atgagcccag aagctggcta atatgggcgt caattagaac aaagaaagga
    80101 agcaataaaa atactccaac tcgcttcaac tgtctcatta tgaattcccc actaattcta
    80161 tcacatctac attatgagta tctgcactca atttaacagt tacttctcgt gtcaaatagt
    80221 ctgtactatg cgttgtggca accacttcac caacaggaat atcagcaacg ttaaagtttc
    80281 ctaatccacc agtagtcacc ttatctcccg cactaatatc gctattacta tttaattggc
    80341 taattttaag aacgtcattt tccttgtcat agccaataat aattccataa attgtagtag
    80401 agccatgttg aattttaaca gaaatcttat cagcattttc cgtatttgtc agaaggttga
    80461 ctatagtaga gttctcctct acttttgaaa cactcccaat caagccacca tttgcaatag
    80521 ctaacatgtt ctcagaagca ccttttgatc tacctgcatc taaggtcaac tcctgcttcc
    80581 aagataccgg agaacgcata ataacatctg ctgctaaagt ctttgtggct tgcaatttag
    80641 acttcatatc aagcaattgg cgcagttgtt cattttctgt ctttaaactt tccacctcat
    80701 ttgatttaac ttctaattgg taaagctgtt tcttcaaact ttcattttca ttatatgttc
    80761 gtgtcaaatg agccaaatct gatttgacag aatcaaacca ctgaaaaggt ttttgtacaa
    80821 ctctatcaac caatgagatt ccatctccta attttgtcac aattgtactt gaataagttg
    80881 tcgctaagag agctgacaca agcagaacag tgacaaaaac aataatgaca tattttgatt
    80941 ttttaaaacg gttcatatcc ctacctttat atcaaaaact gttacagtaa ctttttatca
    81001 attcctgaaa gctactaaga ttttaagaaa aataaacaac aaccaagtac gagaataaca
    81061 agaatggtca gcgtatcctt tagagtccat ttcaattgtc ggtattgact tctgcctttt
    81121 ccaccctgat agccacgcgc ttccatagcg atagccaagg aatctgcacg ttttaaactt
    81181 gtcgcaaaaa gaggaatcaa aatgggaatc atcgacttta ctttttgaac gatgcttcct
    81241 tctccaaaat ccactccacg agctttctgt gcattcataa tccgcgtcgt atcatccatc
    81301 aaggttggga caaaacgcaa actcatagac agcatcaatc caatttcatg aactggaact
    81361 ttcacacgct ttaaaggtgc taataaagct tcgacagctg atgccaaact taaaggcatg
    81421 gttgttaagg ttaacaaagt tgaaaagaaa ataatcaata caaagcgaca aaaaataatc
    81481 ccagcttgtt gcaaagcata atccgtgatt ctcacaaacg aaaactcaaa taaaacattc
    81541 ccattagaaa tgaaaaatag ttgaaaaata gttgtgaagg caatcaagaa aaacatagac
    81601 ttcaagccct gaataaaaaa tgaaagagat actcctgaca aggcaataaa tatccctgtc
    81661 gctataaaaa gaatcagatt cgtcaagggg ttattagccc aaaacacaat caaaatcagt
    81721 agcatcatag caagcaattt gctacgtgga tccaatcggt gaacaatcga atcccctggg
    81781 atataacgcc ctaaaatcat actatccatt tagcgactcc ttgaactcct ctatcttaat
    81841 cggtaatcgt ttaaatgaca cgcctctatc agccaatcgt ttacaaaagg ccgtaatttt
    81901 aggtactccc aactgaactt cttccataaa aacaacgtct tgaaagacat cacttggttt
    81961 gccccccttt actaaacgtc ccttttccat tacatagact tgattcgcat attcagcaac
    82021 atcatccatc aaatgcgtta ccaagacgat ggtcatccct gactggtgga gttttttgaa
    82081 cagggtcatc aactcctttc tccctagagg atctagacca gctgttggct catctaagac
    82141 taatatagct ggctccatgg caagtatgcc tgcaatggca acacgtctca tttgtccccc
    82201 tgacagctca aacggactac gatcaaaaag tgattcatca attccaacca gagccagttt
    82261 ctcacgcgca gtcttcacag catcttcttc agaaactcca aaattttgcg gtccaaaagc
    82321 aacgtccttc aaaaccgttt cttcaaaaat ctgattttca gcaaactgaa ataccaagcc
    82381 aacctgtttt ctaatttgac gaatatcttt atttttagaa gtcgaggtga ttaaggtatc
    82441 aaaaaccctc acactccctt gacttggcac caataaacca tttaagagtt gtaaaatagt
    82501 tgatttacca ctacctgtgt gcccaattaa agctgtataa gagccatctt caatcgtcaa
    82561 agaaacatcc gacaaagctg ctgaagctaa gggagtacct tcttgatatg taaaattcac
    82621 attttctaga gcaattccca tagcttatcc tctagctcac tttctgtcaa ataattttca
    82681 ggtaaattat agccattatg gctcaaagat ttttttaatt gattagcaaa aggatcgtct
    82741 aatccaattt gatctaaatc atttcgagag aaaagctccc ttggactact agttgattca
    82801 atttcccctt ttttcatgac caatacgcga tcactcatgg cgacttcttc caaatcatgg
    82861 gtaatagaaa tgaccgtcat atcatagtct tttcgaattc cttttactgt cccaataagt
    82921 tctctacgcc cctcaggatc caacatactc gttgcttcat ctaagattaa aatagctggt
    82981 cttaggacta caacacctgc aatggccaca cgttgctttt ggccacctga tagacgcgct
    83041 ggctctctct ttttaaagtc caacatgcca actaaatcca gagcttcttc tactctcttt
    83101 ttcatttctt gacgagaaag tccctgattt tccaaaccaa aagcaacatc atcttcaaca
    83161 gtcgctccaa caaattgatt gtctggattt tgaaaaacca taccgatttg acgacgtata
    83221 ttccaaacat tttcctcagt caaacgttgg ccatcaatta caatctctcc ggattctgct
    83281 tccagtaagc catcaattaa tcgaaccgtc gttgatttac cactaccatt atgccctaca
    83341 atcgaaagcc attctccacg tttcacgtga aacgtaatat ccttcacatc gtagtagttc
    83401 tgattttctt tatagcgaaa agaaagattt tttacatcaa ttattgattt catttcgaac
    83461 caaatgtccc tttaaataca taggcactac ccttgaaata gtcatagcca gagtagatag
    83521 tgaaaaataa ggctacataa agtagaactt gaccaagcaa agtccaatgt aatagcaaga
    83581 aaataatggc aaacatctga ctaaaagttt taatttttcc aggcattgct gctgctaaaa
    83641 ttgttccacc agtttcaacc aataaaagcc ttaaacctgt cacagctaac tcacgacaga
    83701 taatcactgc aacaatccaa gccggagcca tacctaactc aatcaacata ataaaagccg
    83761 acataactag taacttatcc gccataggat ctgcaaattt accaaaatta ctgaccacat
    83821 tccatttacg agctaaatat ccatctaaat agtcggtaat actggcaaca gcaaagataa
    83881 tagctgcaac tatatgactc tctatcgaat ttcctatcgt taaaataaag ataaaaatag
    83941 gtataaagag aattcgacct attgttaaga gattgggaat ttgttctttt ttcattcgtt
    84001 tttccttaat ttttagtaaa ggttacagtg atttgtccag tctgagctgt taatttcgat
    84061 aaatcaacag tctgattatc tactgtcaaa tcaacacctt ttacaacacc taacgtaatt
    84121 gttacaggac ttttagttgc aactgttgct tctgcacttt tcttctttgg cgataaggtt
    84181 acaccgccct caagttcgct ttctgaaaca ctgacccaac ttgtaacatc tgaaactgcc
    84241 aattgcaatt taactgtttc cttacttgtc ttataagcga tttctacatg atttccttcg
    84301 cctgatacac ttatagctga ttctatacta gaagaactac tacttgagga gtggggaaca
    84361 gagctagttg aacttgttga ttgaaccaca ctgtaattag aaagagaagg ctcctctggt
    84421 tgagtttgaa tatagttcca aacataataa gtcacaaaaa ttaaaatcga taaagcaaaa
    84481 aggataaaat aaaataaagg taaaaatgat gtttttttct tctttttctt acttgaacgt
    84541 ctacgacctg tcaactcatc ttcatcaaca tctacttcct cataagtaat catactccca
    84601 gaatcataag catccaaaac aatttggtca tctaactcaa cagcccatgc atattttttc
    84661 aagaaagaac gcgtgtaaaa aggacttgga agttgatcga aatcgtctgc ttccattgct
    84721 tccaacatat ctaactggat ttctgtcttt ttctgcaatt catctaaact caatccctga
    84781 ttgattctag ctaatcgtaa aacctctcca attgtttttt ttctcatact tgtcatccct
    84841 tctttctagt gtctattata ataggttact acgatgggaa tattgtaaaa tcaactatgt
    84901 caccatcatc tattaaatga tgtccagcat caaggacatc ctctaaagta atttcctgta
    84961 aaattttcgg caaatcaaaa attgtctcac cattttcaaa agcatcatat tgcgttgcaa
    85021 taaattcaag agagttcatg ctactgaaaa attcgccaaa catctctctt ttgataatat
    85081 ctaaatgttc ctctgtaata tctaaatcct ttgtaaaatt acgaatagcc ttcctaaatt
    85141 gatgagacaa agcaactggc tctttcgtat ccattgtcaa catgacaaaa tgaaagcgac
    85201 ttgttacttc aacttccaga gataaggatg catcaatttt acctgattca taacattttt
    85261 gaaaacgatc cgaagtccaa ccaaacatca ttgcaaacaa taactttaat aaaatatgat
    85321 gtcgatagca atccgcttca gaaacttctc gcttacctct aactccaatc gctagtttgg
    85381 gagaagatac ttccattctc atactatctg ttggctttac aggctgtaaa aacaactttt
    85441 ctcttgctac ttcctgaaaa tctgaatctt tcagttcttt gctttcaaaa tagtcctgta
    85501 ctcgctccac atcaaaatta ccaactaaaa acagagacat gtttacaggt ttgtaaaact
    85561 ttgtaaaatt ttcttgcaaa ttagttagat tgatttggga aatggactcc tcacttccaa
    85621 ctatatcagt tgctaaaggt gtaccaggat acaaattcgc taaagttgaa aagaataaac
    85681 acgaatctgg atcatcttgg tacatttctc gttcttgctg aataatatcc tgctctgtca
    85741 gaatggaagc ttcagtaaag tgtgctgatg ttaccaattc atcaagtaaa tctaaatttt
    85801 ctaaaaaata atccgttgct gaaaaaagat agtttgtttt tgtaaagctt gtaaaggcat
    85861 tactatctgc acctagactc gtaaaagccg acatcaaatc actagaatct tctctctcaa
    85921 ataatttatg ttcaagaaaa tgagcaattc ctccaggata ttgttttaca tctccgtcaa
    85981 cttctgtgac aaacgtatct accgaaccaa actgtacagt gacactcccg taaacctctt
    86041 taaattcctt tttaggcaaa agagcaacta tcaatccatt ggccaaacga gttcgataaa
    86101 ccttttcttt tacagctgga tagtattttt cttcaaaaac aacctttgtc attctattcc
    86161 ttccataaag taaatcgctt gtagtttcac attattagct actctacaaa tagcatcttt
    86221 gtcaatctgt tcaagcttta caatccaact tttaaagtct gctgaagatt ttccaaataa
    86281 ggcattttga taagcacgtt caatcaatga agattgatta tcttaagaaa gtaacaacga
    86341 ccaacgaatc atttccttgg tctgatttaa ctcaaactct gtaaaataac ctttttttaa
    86401 atcaagcagt tgattattca tcattttacg agcctggtta cgattttctc gattgatacc
    86461 agcatacatc ctcaagaatc cactaaataa atcaagctca cttgaaatgg tataagctaa
    86521 tccagcattt tcacggacat ttgtaaagag cttagaatga gcaaatccac caagtaaacc
    86581 attcattaca atcatgggta aatgttgctc atcaccatat ttagaacggt aatgataacc
    86641 taattccaaa atggattgtc ccacattttt ccgaaccata ccttcctgaa ggatattaga
    86701 ataaggttga caatactgaa ccttcacatc tccttttcga cctttaaagc caaatgattc
    86761 taatacattt tgaatttcaa cctcattaaa atcacctagg aaaaagaaat ctattcgatc
    86821 attggctaaa aattcttgga aacaagaata agaactttgt ggagtttcag ctaaaatacg
    86881 atttcgtaaa tcactatatt ccaattgaag acgttcatca tgaaaaaaca atttatccaa
    86941 ttctttatgt gcaaaataaa aagaatcatc catatcagct gctaaacttg ctagcaattg
    87001 ttttttctca atttcaaata aggccggatc aaacccatta tcaactacta cgggtgaaaa
    87061 aagagtttct tttacaagtt ccaaaatctg agaggttagc acgtttttcc tacttaaaaa
    87121 ctcatcacga acataggtaa atgtcaattc tataatgtgg ctttgccctc ttctgaaaca
    87181 attggttgac atatctgtac cgtatagact ggccaagtgt ctcctcaaat cttgagaagt
    87241 ggggtacatc tgattagcag tctctagcat acttgcactc aacatgtgac ctgcaatcgt
    87301 atcaagggat aatggagcgg taaaacgcac ggtaattttg tttgttttaa acttttttga
    87361 ttggataaaa tgtgttgaaa ttccatgcac taactccatg atttacctcc ttatatacag
    87421 acttctatta tatcacgaaa acctgaaatt ttcttattcc ctgtaacact tttgaaataa
    87481 aaatcgctta catttctctc tgtctctctc actattttta ggaaaatatg gtataatacc
    87541 aaagattgag gtgaattatg gaatacaaat tatttgaaga atttattacc ctccaagcac
    87601 tactcaaaga acttggaatt acacatagcg gaggagctat taaatcattt ctctctgaac
    87661 attctgttta ctttaatagg gaattagaga gtcgtcgtgg aaaaaaactt cgtattggcg
    87721 ataaagttga catccctgac atgaacattg acatcttgtt gacacaacct acttctgaag
    87781 aacaagatga ataccaagct gataaagttg aaaaagaacg gatcgctaaa cttgtcaaaa
    87841 agatgaataa gggagttaaa aaagacaaat cgaaacctgc ttcatcacct aaaagccaac
    87901 aagctccacg attccctggt agataatcat gtggctacaa catctatctc tcaagacttt
    87961 tcgtaattac aaagaaacga aaatagactt taatcctaaa ttgaatgtct ttttgggacg
    88021 taatgcacaa ggaaaaacaa acatgttaga ggctatctat tttttagcct taacgcgtag
    88081 tcatcgaact cgaacagata aaaatctcat tcattttgat gaggaacaac ttcatctttc
    88141 aggtctcgtt cagaaaaaaa ctggatccat tcccctagaa atcgaactaa cacaaaaagg
    88201 ccgtgtaaca aaagttaatc acttaaaaca ggcacgcctt tcagattatg taggacacat
    88261 gaatgttgtc ttatttgctc ctgaagattt acaactaatt aaaggagcac cttcgattcg
    88321 acgaaaattc attgatatgg aacttgggca aattaagcca atctacttat ctgacttaac
    88381 caattataac cacatcctaa agcaaagaaa cacttaccta aaatcagatc aaaaaataga
    88441 tgaaacattc ctttctgtgt tagatgatca gctagttgat tatggatgtc gtgtaatgaa
    88501 tcaccgctta gatttcataa aaaaactaga atcatttggg cgtaagaaac attttgaact
    88561 ctctaatcag atcgaagagt tgtcaatatc ctatcaatct tctgtcaata taactgacaa
    88621 acaaaactta tccgaatctt tcaaaattgc tttagaaaaa agtaaatcca gagatttatt
    88681 taaaaagaat actggtgtcg gtcctcatcg agatgacatt tctttttata taaatgggat
    88741 ggatgctagt ttcggaagcc aaggtcaaca tcgtagtctc gtcctctcga taaaattagc
    88801 agaaatcgaa ttaatggaaa gcattaccac agaatctccg atattactgc ttgacgatgt
    88861 gatgagtgaa cttgacaaca ctagacagtt aaaattatta gaaacgattt ctcaatcaat
    88921 ccaaaccttt atcacaacaa caagcttaga ccatcttcaa aatctgccag aaaatctaag
    88981 tatcttcact attcaggatg gtaaagctgc tgtaaatgga aattgacaac attataaaag
    89041 aactcctgtt ttcactggag ttcttttcat tgttttttac atagaataat ttggtgcctc
    89101 attagtaatt tgcacatcat gaggatggct ttctttcaaa ccagcaccag acatttcaat
    89161 aaattgagca ttatcgtgta gttctttaag gttagctgca ccacagtaac ccataccaga
    89221 gcgaatacca ccaatcattt ggaaaacaat atcagctgcc gctcctttat aagcaacacg
    89281 accttcaatt ccttctggaa caagcttgtt tgcttcattg acagaacctt ggaaataacg
    89341 gtcgcttgaa cctttcttca tagcagcaat tgatcccata ccacggtaag tcttgaattt
    89401 acgtccttgg aagatttcag tttcgcctgg agcttcatca gttccagcaa acatagatcc
    89461 aagcataaca gcatttccac ctgcagcaag tgcttttaca atatctccag aatacttgat
    89521 cccaccgtca gcaataatcg ttttaccata ttcgcgcgca acagctgcag catcgtagat
    89581 agctgttact tgcggaacac caacaccagc aatcacacga gtagtacaga tagaacctgg
    89641 tccaatacca accttaacaa cgtctacacc cgcttcataa agggcacgtg caccttcagc
    89701 agtagcaata tttccagcaa tcaaagtccg atctgggaaa tgagcacgaa tctcggcaat
    89761 tttacgcaag acacctgcag aatgaccatg tgcagtatca ataacaatcg catccgctcc
    89821 tgcctcaaaa agagcctctg cacgttcaaa tgtatctgaa gtaacaccta ctgcacctgc
    89881 aactagaaga cgaccaaact catctttagc cgcatttgga aactcaataa ctttttcaat
    89941 atctttgata gtgatcaaac cagaaagact gccttcttca tcgaccaacg gaagtttttc
    90001 aatacgatgc tcttgaagaa tactctcagc cgttgcaaga tccgtaccca caggagcagt
    90061 aacaagattt tcactagtca tatggtttga aattggttga ttataatctg aaataaaacg
    90121 aagatctcgg tttgtcaaaa taccaaccaa tttacgattt tcaagtgttt caacaactgg
    90181 aacaccactg atgcggtaac gacccataag ctcatctgct tcagcaattg tatgttcagg
    90241 cgtcaagaag aacggatcaa taataactcc attttcagaa cgttttacct tacgaacctc
    90301 gtctgcttgt tgagcaattg acatgttttt atggataact ccgagaccac ctgcacgagc
    90361 aatagcaatg gccatttgac tctctgtaac tgtgtccatg gcagcggtaa taattgggat
    90421 atttaaagtc aaattatctg ccaatttagt tgttaaatct gcatcgttag gcaacacatg
    90481 actttcagct ggaataagca atacatcatc aaaggtaaaa ccttttttca aaaatttagt
    90541 gtcccaatta gacattcgaa gtttcctctt ttctttcttt ttgagcttga ctctttttat
    90601 attgtatcta tcataccatt ctatacaaat ttgtcaaatg ttacaggggt aaataaaaaa
    90661 ctatcttttc ttcgagatag aaatgatagt ttcttgtaaa ataaacttag ttaaagtaat
    90721 gaagtcccat tgcccctttt acctcagata gggtttgacc cgcaacttca cgcgctcttt
    90781 cactaccttt ttgaatcata ttataaactt ctcccatatc cttagcaaat tcaatacggc
    90841 gctcacgaat aggacccagt tcacgttcta atatttcaag tagataacgc ttggtcttca
    90901 catcaccaag accacctcgt tgataacgtt ctttcatatc agcaatttct tgagcatctt
    90961 ctggacgacc aaaaacatct agataatgga aaaccatatt tccctcaatc ttacctggat
    91021 cctcaacgcg gatatgatct ggatctgtat acatactcat tactttttta cgcaaagtat
    91081 ccgcatcatc agctaaataa ataccattat ttagtgattt agacatttta gcatttccat
    91141 ctaaaccagg caaacgccct gctctctcat tttctggata aataccttcc ggctctacca
    91201 agacatcaca gttatatgca ttgttaaaag aacgaacaat ttcacgagtt tgctcaatca
    91261 ttggtttctg atctgtccca acaggaacat aattagcctt gaaagctgtg atatcagctg
    91321 cttgagcgat tggatagacc aagaatcctg tcggaatgct ttctccaaat cctttctgag
    91381 aaatctctgt cttgactgtt ggatttcgct ccaaacgtgc taacgaaact agattcatat
    91441 aatacataga caactcagcc aactctggaa tctggctttg aataaaaata gttgacttat
    91501 ttggatccaa tccaactgca agataatcca aagccacatt tccgatagac tctacaatgg
    91561 tttgaggatc tttggcatga tctgtcaagg cttgttggtc agccaagaac acaaacatat
    91621 catacttatc ctcttcctgt aataatactc gatttttgag acttccaaca taatgtccaa
    91681 tatgcaattt tcctgttgga cggtctcctg ttaaaataat gggtttagtc attttgttct
    91741 ccttcgatat agtcctttca attatagcat ttttttaatg aaataaccgt aatttatcaa
    91801 aataaatcag ccttgctttt tacagatttg tgtaaaggat actgtaaata taatttacac
    91861 aaaattgaca aataaaaatt tgaatatttc tgtattttct agtagaataa atatattaca
    91921 catataggag aaaaatattg cttacagtat ctgatgtttc actacgtttt agtgatcgca
    91981 aactttttga tgatgtcaat atcaaattta cagaaggaaa tacttacgga ttaatcggtg
    92041 ctaatggtgc cggaaaatca acctttttaa aaattttagc tggagatatc gaacctacta
    92101 ctggtcacat ctctcttggt ccagatgaac gtctctctgt tcttcgtcaa aatcactttg
    92161 actacgaaga tgaacgtgcc attgatgtcg ttatcatggg aaatgaaaaa ctttatagca
    92221 tcatgaaaga gaaagatgct atctacatga aggaagattt ctcagacgag gacggggttc
    92281 gtgctgccga actcgaagga gagtttgccg aacttggagg ttgggaagca gagagtgaag
    92341 cctctcaact acttcaaaac ctaaacattc cagaagaatt acactaccaa aacatgagcg
    92401 aattggccaa cggtgaaaaa gtaaaggttc tcctcgccaa agcacttttt ggtaaaccag
    92461 atgttcttct cttggacgag cctactaacg gtttggatat ccaatcgatt acttggttag
    92521 aagacttctt aattgacttt gataacacag ttatcgtagt atcccacgac cgtcacttct
    92581 taaacaaagt ttgtactcac atggccgacc ttgactttgg aaaaatcaaa ctctatgtcg
    92641 gaaactacga cttctggaag gaatcttctg agcttgctgc taaattgcta gcagaccgta
    92701 atgctaaagc agaagaaaaa attaaacaat tgcaagaatt cgttgctcgt ttctctgcca
    92761 atgcttctaa gtcaaggcag gcaacatcac gtaagaaaat gcttgataag attgagctag
    92821 aagagattgt gccatctagt cgtaaatatc catttatcaa ctttaaagcg gaacgtgaga
    92881 ttggtaatga tctcttgaca gtagaaaatc taactgtaaa gattgatggt gaaactatct
    92941 tggataatat tagtttcatc ttgcgtccag atgataagac agcacttatt ggacaaaatg
    93001 atattcaaac gactgcatta attcgtgcaa tcatgggaga tattgactat gaaggaactg
    93061 tcaagtgggg agttacaact agtcaatctt acctaccaaa agataactca gctgattttg
    93121 caggaggaga atcaattctt gactggttgc gtcaattcgc aagtaaagaa gaagatgaca
    93181 atactttcct acgtggcttc ctcggccgta tgctcttctc tggagatgaa gttaacaaac
    93241 ctgtaaatgt cttgtcaggg ggagaaaaag ttcgtgtcat gctttcaaaa ctcatgctct
    93301 taaaatcaaa tgtccttgta cttgatgatc caacaaatca cttggacttg gaatctatct
    93361 caagcttgaa tgatggattg aaaaacttta aagaatcaat catctttgct agccatgacc
    93421 acgaatttat tcaaactttg gctaaccata tcattgtctt atctaaaaat ggcgtcattg
    93481 accgtatcga tgaaacctac gatgaattcc tagaaaatgc agaagtacaa gcaaaagtta
    93541 aagaactttg gaaagactaa ataaaacttc aaaactcagt tgggttaacc aactgagttt
    93601 tctatcattc tacgaggtaa catgaaatca tttttaaaaa catatcgaac ctattttatt
    93661 tctttcatca ttcctgtagt gattatgtct ggagtatatc tatctcaagg tatctactgg
    93721 aatagcgaca actctcctct attaggagat ggctttcatc aatacgttat ttttgatgta
    93781 gccttacgaa atatcctaca tggaaatagt agtctgtttt acacctttac aagtggtcta
    93841 gggctaaact tctatgccct atctagttat tacttgggta gttttctcgc gcctctagtt
    93901 tacttttttg atctaacgaa tatgccagat gctgtctatc tgaccactct cttaaaattt
    93961 ggattgattg gtctgtcaac cttttttaat ttgaataaat tgtttcaatc tatccctcag
    94021 actttaaaac tagccttatc tacttcctat gctctgatga gtttcactgt cagtcaatta
    94081 gagataaaaa cctggctaga tgtttttatc ttgattcctt taattataac tggtttacat
    94141 ctactgataa ctgaaaagaa actcctattg tactttacaa gtctgtcaat cttatttatt
    94201 caaaattatt attttggata tatgacagta ttgtttctta ttttctggta tctctgtcaa
    94261 atttcgtggg actttaagac tcgaaaatca tctgttcttg atttcatagt tatctccttt
    94321 ttagctggta tggctagttt gattatgact cttcccactc tatttgattt acagacacat
    94381 ggggaaaaat tgactgaagt tacaaagttt caaactgaaa gtagctggta tcttgatctc
    94441 tttgctaagc aattcattgg ttcctttgac acaacaaagt atggggccat cccaatgatt
    94501 tttgttggac tatttccctt tattttgacc attttatttt ttacgctgaa atctattaag
    94561 tttcacgtga aactcatata tgtaatattc tttgcatttc taattgcaag cttttacata
    94621 gaagctcttg acttattttg gcaaggcatg catactccaa acatgttttt acatcgctat
    94681 gcttggattt tctctacctt gttaatttac acagcagcag aagtcttaaa gcgtctgaaa
    94741 gaacttaaag tctggaattt tttagtttcg ctttttcttg tagtagcagg atttttagct
    94801 accatctatc taaaatcgca ttattctttt ttaacagatt tgaatattct gcttactctt
    94861 gaatttttgg ttgtctattc tcttttactc cttgcagtta tcaaaaagtt tatatctgtg
    94921 aatctatttg ccattctaat ctctttattt atactggttg aaatgagttt aaatgcttca
    94981 tctcaaatgg acggaattgc taaggaatgg ggatttgctt ctcgaagtgc ttatagtcga
    95041 gatatcccag ctatggaatc tttctcaaca tatattggaa atcaatttac tcgtactgaa
    95101 aaactacaaa ctcagacagg aaatgacagt atgaaattca actacaatgg aatctctcaa
    95161 ttttcatctg ttcgaaatcg ttcatcaagc tctactttag ataaacttgg ttttaaatcc
    95221 tctgggacta atctcaatct ccgatatgca aataatagta ttttggctga tagtttattt
    95281 ggtatccagt acaatatctc agacagtcct attgataagt atggctttaa agatatctat
    95341 caaaaagctg atagtttatt tggtatccag tacaatatct cagacagtcc tattgataag
    95401 tatggcttta aagatatcta tcaaaaagat aatcttaccc tatatgaaaa tcaatactct
    95461 cttccgattg cagttgctag tcaatctgtt tacaatgatg tcaagttcaa tgaacatacc
    95521 ttggataatc aggcctcatt tttaaatcaa cttgctaacg tcaattttga ttatttttct
    95581 ccaatacctt atgaaaaaac agaaaaaata gaaaatacta atgatttgat tagtgtcaca
    95641 agttcttcaa atgaagatgc agcaatccag tatcaaattg aagttccaga aaacagccaa
    95701 gtttatctct ctttcataaa ccttcacttt tctaacgata aacaaaagaa ggttgacata
    95761 cttgtaaatg gtgaaaaaaa gacttttaca actgataatg tcttctcctt ctttaatcta
    95821 ggatatacta aagagaaaaa aactttcaat atcaatgtta gtttccctgg aaattcacaa
    95881 gtatcatttg aatctcctac cttctatcgt ttagatacca aaactttcac cgaggcaatt
    95941 caaaaaatta aagaacaacc tgtcacagta tcaacttcta aaaacaaggt ttttgctaca
    96001 tatgatgtcc aacaagatac atctattttc ttcaccattc cttatgacaa aggttggtct
    96061 gcctaccaag atggtaagaa aatagaaatt aaacaagctc aaactggatt tatgaaagtt
    96121 gacattccca aggggaaagg aactattaca ctttccttca ttcccaatgg ttttattact
    96181 ggagcaatct gttcctttac ttctctctta ctatttggaa tctataatca cagacgaaag
    96241 tcatctaagg cataaaaaat cgaccagtta atcggtcgat ttttttaatc ttcttccatt
    96301 ttcttatgtt gataggctag catacctaaa ccagtaaata gagctagtat gacagctagg
    96361 aaaatgactt gttgatagag attgtttgtc gtaatcccga aactgaatag ctcattggta
    96421 accagggatt aatagatcta aagaaatcat ttgtcaaagc aagtggataa gtacctgcac
    96481 ttgatgctaa ctgtagtaaa agcaaaataa gtgagaaaaa agctcctata cggctattcc
    96541 acgttgctaa agtggtcacc atagacatga atactaaact tgttaggatg atgagaataa
    96601 atattctcat ctcatgatta gcagttaaac caataagctg aactcctcca tataccaaaa
    96661 ttcctgccaa aacagctata ataccattta tttcagctca agatttcaac caagcccaac
    96721 ggctctctgg atgacgtcct gaaggcaatt tcgcaaatat catatttgtt gatattgctg
    96781 caaaaaaaag agcaactgat atcatataag gagctattgc gattccattt acaggaactt
    96841 gatcattgtc tgtttttgaa agattgagtg gatttgacaa aatctctgca tttttagatt
    96901 ctgttgatac tgatttgagt tgatcactag cattacctag tccttgtcct aaagaagcaa
    96961 gtcctgtctg taaatcttcc aatccagaag ttaactttgt tccaccttct gctagtttcc
    97021 cagatccatc tgccaattta ttagctctat tctctaatgg agaagcacct gaaagtaact
    97081 gactggattt gtctgctaat tgcccagatc ctgattgtaa ttaaccaact cctgctgtca
    97141 atctagaaga tttttgtgtc aaggtgtttg agcctgaaac tagtttatcc aaactacctg
    97201 tcaaggtggc atttttttca cttagttgac ttgcgccctg agaaacttta tcaacacctg
    97261 tagtatatgc gtttacacct gatgcaatca actgactggc aggaactaat ttgctagtaa
    97321 cagctccttg tatctctgtt aatccacttg acaatcctat caaagaagta gaagtaatag
    97381 gtaatacttg attagcttga ttttttaaag tcgaaagatt agaagattga ttttgtaagt
    97441 tttctaaact tccctgtaaa ccttgtacta aagctacaat tgactgagcc gattgaatac
    97501 tatcagttga attttgagat acagaatcac ttatcccagt ttgttgctca cttgtcaatg
    97561 attgataagc tgctgtcgat tgaatattgg ataatgtagt tgttttttta gataaatcac
    97621 ttggtaaagt cactaccata tagtaatcgc catcttccaa tcccttcttt ccttcctctt
    97681 catctacaaa atgaaaatcc aaggttttat tttcttttaa attggacacc atgtcttttc
    97741 ctattgccat agtattacca ttataggaag cctctttatc attatttaca actgccacag
    97801 gtaagtcaga caattgccca tatggatccc acattgatga caaaaatatg atattgtaca
    97861 gagctggaat aagagaaatc ccgatcatga caataataaa ggttgttttt tttaaattgc
    97921 tttccattct ttaaacatag tttctccttt tttaaacata ttgtctaaaa ttttgatata
    97981 atagattata cattaaaaaa tctaaattac aagataaaaa atctattttt agacatatag
    98041 tctaatttgt ttacaaggag gaaatatgca agaaagtaac aaacgcttaa aaacaaagcg
    98101 aactattgaa aatgctatgg tacaattact gatggaacag ccatttgata aaatttctac
    98161 tgtcaaatta gtagaaaaag ccggaattag tcgttccagc ttctatactc actataagga
    98221 taagtatgat atgattgagc actatcaaag caagctattc catacatttg aatatatttt
    98281 tcaaaaacat gctcatcaca aaagagacgc tattttagaa gtttttgaat atctagagtc
    98341 agaaccactt ctggctgccc ttctttctga aaatgggact aaagaaatcc aaaatttctt
    98401 acgaaataaa cttcatatca tgcttagtac agatttacaa aagcgattta tgcaactgaa
    98461 tctaaatacc actgaattag aatatagtag catctatcta actcatgcac tttttggtgt
    98521 ctgccaaact tggattgcac atggaaaaaa agaaagttct caagaaataa cagacttcct
    98581 tatgaaaatg cttggtgata caaattgata caaaaagagg aacacagctg tgttcccttt
    98641 tatctatact ccgccagtag gactcgaacc tacgacatca tgattaacag tcatgcgcta
    98701 ctaccaactg agctatggcg gataaaatag tccgtacggg attcgaaccc gtgttaccgc
    98761 cgtgaaaagg cggtgtctta accccttgac caacggacct tctatctgta gcagatataa
    98821 ccattatatc aatttcttgc taattgtcaa tcacttttga gattttttct ctaaaatatc
    98881 ttttaatttt ctaattttta atcttgaaat aggacaacga tggtcttcat agaaaacaat
    98941 ttctaagttt tttcgatcaa tttctctgat attgcctata tttaccaaaa atgacttgtg
    99001 aggagaataa aatcgctgag tatgtttgtc cttttcctga atatctgtca tggtaccata
    99061 aaactctttt gcaaaattct taccaataat gcgcaattta tgagataccc ctgttgtttc
    99121 aatatacaaa atatcatggt aaggaatttt taaatcattt cccttgtaat tgtagtcgaa
    99181 ataatctaca acatcttcat tttcaagtaa catactcttc gtgtagaaga tattttgctc
    99241 aattctcttc ttaaacatct catcattgat atccttatca acaaaatcta gggctgatac
    99301 ctggtattta taggttagag tcgcaaactc tgatcgacta gtgataaaga cgataatagc
    99361 gtaaggattg taatgacgaa tgagctgagc cacttcaaat ccctttttct caattccatg
    99421 aatatcgata tctaggaaat aaagctgatt tacttcatca ttttcaatgt attcttcaaa
    99481 ttcacggact tttcccgttg tcttgtatga tattggaata ttcgattctt tcgaaatttc
    99541 atccaatatt ctctctagtc tcacttgatg ttcaataaca tcttctaaaa ttaaaacttt
    99601 cattcaaatt ccctcttaaa tctaatgatt tgtctaaatg tactgccttc catctctgtt
    99661 tctaaaataa tattgttgta cttatctagt agttctttca cattatttaa tccgactccg
    99721 cgatttcttc ccttagtgga gaatcctaag gcaaatagat ctcctgaagg agtcatcgtc
    99781 attttacatg aattctgaat cacaataact gtttcagttt ccatcttaat aactgctact
    99841 tccatctgct ttttatagct atcagccgat ccttcgacag cattattcaa taaaacgctc
    99901 atgatacgaa ccaaatccaa tagttcaatt ggaagcttgg taatcgtatc ttttacttcc
    99961 agtgtaaact ctacaccatt atttcgagca tagacaattg actgagcaac caaacttcgt
   100021 aaagctgagt cttctatgtt gttcaaatca aagtaagtgt acttatctga acgcaattta
   100081 tgatttgctt tgactaaaac ttcattgtaa attctgtcaa tttcctgtaa attaccactg
   100141 tcaattgcca tctgcatgct gacaagcatt ccagcataat catgtcgaaa accacggatt
   100201 tcattataca gaccaacaat ttcatctgtg taattctgta aatgtttctg ttcaaatttc
   100261 ttctgcttca aagcaatctc tttctccatt tgaactttat gagaattcat tgcaaagaag
   100321 gtcaaaagga gagagataaa gacaatagat gacaaaatac ttccaaaact attcaaatgt
   100381 ttaatcgtac ttaccatatc tgaaacgaaa gatacaatat gtagcaatag taaagcaaaa
   100441 aatacttttt tcaagaaagg ataaaggtag tcctcgtcaa aataggctag ttccaaatgg
   100501 aaatagtaaa tgatttttaa tgtaacaaaa taggttaaca ccgtcacaac gaaaaagaat
   100561 gggaaatgat attgtaaaac aaaattatct cctgttatag aggagaaagt tacggacaga
   100621 aagttatgag tgctctcata taaaagagat agtagtaaac ttaggaatag tcctctatcc
   100681 ctctcatact gtttcatcca tcgaaaatag gaatataatc ccaaaggaaa taaaaatctt
   100741 tcaatcccta acccatctaa atatagaata tataagggaa aatcaaatac tatttctgtt
   100801 agtaatgtat aagcaccaaa aacgaataat tcttttctat ttatttgacc tttacaaata
   100861 aaatggtaac tgtgactaat aattaaaaaa tgaacaataa ccgtcccaaa tccaaataaa
   100921 tccattactc tttcccctta tttcattact tttttctttg taaaataaaa tcacggaaga
   100981 attttgacaa cctcatctcc ccacctttaa tcttttgtaa gtctttttcc ttcaaagcta
   101041 caaactgttc caatttaact gtgtttttca taataaaatc tcctaaaatg ttttttcttg
   101101 taagctaact tacaaaaacc attatacaaa atggaatttc gttttagata aaattctctc
   101161 aactgtcatt tttttctccc aaagtgtact tttttaagaa aaaagccggg aaaattccca
   101221 gctttgctat tatattgatc ccagcaggat tcgaacctgc gaccgttcgc ttagaaggcg
   101281 aatgctctat ccagctgagc tatgagacct aatacaatta ttctaccaaa aattcaatta
   101341 aaagtcaatt ttctatttat ggtaggggaa tccctgctga atcgtaaaag cgcgatagat
   101401 ttgttcaaca agaactagtc tcattaactg atggggtaag gttaggcgac caaaactgac
   101461 agaaagattg gctctatttt ttacagatga tgacaatcct aaacttcccc caataataaa
   101521 agtaagagta gaaaatcctt ttatagaagt ttcttctaac tgcttactaa attcttctga
   101581 gaagaaagtt ttcccttcaa tggctaacac aataacgaaa tcacggtcag caatttttga
   101641 taaaattctc tgaccttcta tttctaaaat cttttgattt tctgattcac tggccttatc
   101701 tggtgttttt tcatctgata actcaatcat ttcaaactta gcaaatctag aaattcgttt
   101761 tgaatactct gcgataccat cttttaaata cttttctttc agtttcccaa ctgttacaac
   101821 tttaattttc atgactctat tctaacatat tctctatttt ttcacatctt attcacaaaa
   101881 taaaaaatag atttcaatta agaaaatcac agtttcaaaa gagttatcca cagtttgtgt
   101941 aaaacttttg tgtttaagtt ataattaagc tagtcagttt atactttcag taattcaaac
   102001 atatggaggc aaatatgaaa catctaaaaa cattttacaa aaaatggttt caattattag
   102061 tcgttatcgt cattagcttt tttagtggag ccttgggtag tttttcaata actcaactaa
   102121 ctcaaaaaag tagtgtaaac aactctaaca acaatagtac tattacacaa actgcctata
   102181 agaacgaaaa ttcaacaaca caggctgtta acaaagtaaa agatgctgtt gtttctgtta
   102241 ttacttattc ggcaaacaga caaaatagcg tatttggcaa tgatgatact gacacagatt
   102301 ctcagcgaat ctctagtgaa ggatctggag ttatttataa aaagaatgat aaagaagctt
   102361 acatcgtcac caacaatcac gttataaatg gcgccagcaa agtagatatt agattgtcag
   102421 atgggactaa agtacctgga gaaattgtcg gagctgacac tttctctgat attgctgtcg
   102481 tcaaaatctc ttcagaaaaa gtgacaacag tagctgagtt tggtgattct agtaagttaa
   102541 ctgtaggaga aactgctatt gccatcggta gcccgttagg ttctgaatat gcaaatactg
   102601 tcactcaagg tatcgtatcc agtctcaata gaaatgtatc cttaagatcg gaagatggac
   102661 aagctatttc tacaaaagcc atccaaactg atactgctat taacccaggt aactctggcg
   102721 gcccactgat caatattcaa gggcaggtta tcggaattac ctcaagtaaa attgctacaa
   102781 atggaggaac atctgtagaa ggtcttggtt tcgcaattcc tgcaaatgat gctatcaata
   102841 ttattgaaca gttagaaaaa aacggaaaag tgacgcgtcc agctttggga atccagatgg
   102901 ttaatttatc taatgtgagt acaagcgaca tcagaagact caatattcca agtaatgtta
   102961 catctggtgt agttgttcgt tcggtacaaa gtaatatgcc tgccaatggt caccttgaaa
   103021 aatacgatgt aattacaaaa gtagatgaca aagagattgc ttcatcaaca gacttacaaa
   103081 gtgctcttta caaccattct atcggagaca ccattaagat aacctactat cgtaacggga
   103141 aagaagaaac tacctctatc aaacttaaca agagttcagg tgatttagaa tcttgattga
   103201 catctatgta aagaaagctt tacataagag aaaagatgtg ttagtgtaga atcatggaaa
   103261 aatttgaaat gatttctatc acagatatac aaaaaaatcc ctatcaaccc cgaaaagaat
   103321 ttgatagaga aaaactagat gaactagcac agtctatcaa agaaaatggg gtcattcaac
   103381 cgattattgt tcgtcaatct cctgttattg gttatgaaat ccttgcagga gagagacgct
   103441 atcgggcttc acttttagct ggtctacggt ctatcccagc tgttgttaaa cagatttcag
   103501 accaagagat gatggtccag tccattattg aaaatttaca gagagaaaat ttaaacccaa
   103561 tagaagaagc actcgcctat gaatctctcg tagagaaagg attcacccat gctgaaattg
   103621 cagataagat gggcaagtct cgtccatata tcagcaactc cattcgttta ctttccttgc
   103681 cagaacagat tctttcagaa gtagaaaatg gcaaactatc acaagcccat gcgcgttccc
   103741 tagttgggtt aaataaggaa caacaagact atttctttca acggattata gaagaagata
   103801 tttctgtaag gaaattagaa gctcttctga cagagaaaaa acaaaagaaa cagcaaaaaa
   103861 ctaatcattt catacaaaat gaagaaaaac agttaagaaa actactcgga ttagatgtag
   103921 aaattaaact atctaaaaaa gacagtggaa aaatcattat ttctttttca aatcaagaag
   103981 aatatagtag aattatcaac agcctgaaat aaggctgttc ttttattttt ttatctcaca
   104041 aggttatcca ctatgttttt cgataaaaag cttaataaat caataatttc ttcttttatc
   104101 cccaacctgt ggataaagtt tggtaacatt gtggattatt tttcacagct tgtggaaaat
   104161 tcttgctatc tatggtaaaa tatctctagt attaaacttt taaatagtaa aggaggagaa
   104221 aggattgaaa gaaaaacaat tttggaatcg tatattagaa tttgcacaag aaagactgac
   104281 tcgatccatg tatgatttct atgctattca agctgaactc atcaaggtag aggaaaatgt
   104341 tgccactata tttctacctc gctctgaaat ggaaatggtc tgggaaaaac aactaaaaga
   104401 tattattgta gtagctggtt ttgaaattta tgacgctgaa ataactcccc actatatttt
   104461 caccaaacct caagatacga ctagctcaca agttgaagaa gctacaaatt taactcttta
   104521 taactatagt ccaaagttag tatctattcc ttattcagat acgggattaa aagaaaagta
   104581 tacctttgat aactttattc aaggggatgg aaatgtttgg gctgtatcag ccgctttagc
   104641 tgtctctgaa gatttggctc tgacctataa ccctcttttt atctatggag gaccaggcct
   104701 tggtaagact cacttattaa acgctattgg aaatgaaatt ctaaaaaata ttcctaatgc
   104761 gcgtgttaaa tatatccctg ccgaaagctt tattaatgac tttcttgatc acctaagact
   104821 tggggaaatg gaaaagttta aaaagaccta tcgtagtctt gatcttttgt taatcgatga
   104881 tattcagtca ctcagcggaa aaaaagttgc aactcaggaa gaatttttca atacctttaa
   104941 cgcccttcat gacaagcaaa aacagattgt cctaacgagt gatcgtagtc caaaacatct
   105001 agaagggctc gaggagaggc ttgtcacgcg ttttagttgg ggattgacac aaactatcac
   105061 accccctgac tttgaaacac gtattgccat tttacaaagt aaaacggaac atttaggcta
   105121 caatttccaa agtgatactc tagaatacct agctgggcaa tttgattcaa atgttcgaga
   105181 tcttgaggga gccatcaacg acatcacttt aattgccaga gtaaaaaaaa tcaaggatat
   105241 cactattgat attgctgcag aagccattag agcccgcaaa caagatgtta gccaaatgct
   105301 cgtcatccca attgataaaa tccaaactga agttggtaac ttttatggtg ttagtatcaa
   105361 agaaatgaag ggaagtagac gccttcaaaa tattgttttg gcccgtcaag tagccatgta
   105421 tttatctaga gaactaacag ataatagtct tccaaaaatt gggaaggaat ttgggggaaa
   105481 agatcatacc acagtcattc atgcccatgc caaaataaaa tctttgattg atcaagacga
   105541 taatttacgt ttagaaattg aatcaatcaa aaagaaaatc aaataatttg tggataactt
   105601 ttagtttttt atctttttta tccacatttt ttaaacaagc taaaaaactt gatatgactt
   105661 gtttaaaggc tgttttccac agatttcaca gactctatta ttactattat ctttctaata
   105721 ctaaaaataa ataaaggaga atccatgatt catttttcaa ttaataaaaa tttatttcta
   105781 caagcattaa atactactaa gagagctatt agttctaaaa atgccattcc tattttatca
   105841 acagtaaaaa ttgacgtgac caatgaaggt attactttaa ttggttcaaa tggtcaaatt
   105901 tcaattgaaa attttatttc tcaaaaaaat gaagatgctg gtttgttaat tacttcttta
   105961 ggttcgatcc ttcttgaagc ttctttcttt atcaatgtag tatctagttt acctgatgta
   106021 actcttgatt ttaaagaaat tgaacaaaat caaattgttt taaccagtgg caaatcagaa
   106081 attaccctaa aaggaaaaga tagcgaacaa tatccacgaa tccaagaaat ttcagcaagc
   106141 actcctttaa tacttgaaac aaaattactc aagaaaatta ttaatgaaac agcctttgct
   106201 gcaagtacac aagagagtcg tccgatttta acaggtgtcc acttcgtatt gagtcaacac
   106261 aaagagttaa aaacagttgc aacagactct catcgcctaa gccagaaaaa attgactctt
   106321 gaaaaaaata gtgatgattt tgatgtcgta attcctagcc gttctctacg cgaattttca
   106381 gcggtattta cagatgatat cgaaactgta gagattttct ttgccaataa ccaaatcctc
   106441 tttagaagcg aaaatattag cttctatact cgtctcctag aaggaaacta tcctgataca
   106501 gatcgcttga ttccaacaga ctttaacatt actattactt ttaatgtggt aaacttacgc
   106561 cagtcaatgg agcgtgcccg tcttttatca agtgcgactc aaaatggtac tgtgaaactt
   106621 gaaattaagg atggggttgt tagcgcccat gttcactctc cagaagttgg taaagtaaac
   106681 gaagaaatcg atactgatca ggttactggt gaagatttga ccattagttt caacccaact
   106741 tacttgattg attctcttaa agctttaaat agcgaaaagg tgaccattag ctttatctca
   106801 gctgttcgtc catttactct tgtgccagca gatactgacg aagacttcat gcagctaatt
   106861 acaccagttc gtacaaatta agtgaaagag gttgagcctg gctcgcctct tttatgatat
   106921 aatcgaaaaa gaaaaggaga gtagtatgta tcaagttgga aattttgttg agatgaaaaa
   106981 atcacacgct tgtacaatca agtcaactgg taaaaaggct aatcgttggg aaattacacg
   107041 tgtaggagca gatatcaaaa taaaatgcag taattgtgag catgttgtca tgatggggcg
   107101 atatgatttt gagcgaaaaa tgaataaaat tattgactga gaacccttag ttagagggtt
   107161 agcactttat ccctttttgt gttataatat tagggattga aatgaaaacg gagaatgaga
   107221 aatatggctt tgacagcagg tatcgttggt ttgccaaacg ttggtaaatc aacactattt
   107281 aatgcaatta caaaagcagg agcagaggca gcaaactacc catttgcgac tattgatcca
   107341 aatgttggaa tggtggaagt tccagatgaa cgcctacaaa aactaactga aatgataact
   107401 cctaaaaaga cagttcccac aacatttgaa tttacggata ttgcagggat tgtaaaagga
   107461 gcttcaaaag gagaagggct agggaataaa ttcttggcca atattcgtga agtagatgcg
   107521 attgttcacg tagttcgtgc ttttgatgat gaaaatgtga tgcgcgagca aggacgtgaa
   107581 gacgcctttg tagatccact tgcagatatt gatacaatta atctggaatt aattcttgct
   107641 gacttagaat cagtgaacaa acgatatgcg cgtgtagaaa agatggcacg tacgcaaaaa
   107701 gataaagaat cagtagcaga attcaatgtt cttcaaaaga ttaaaccagt cctagaagac
   107761 gggaaatcag ctcgtaccat tgaatttaca gatgaggaac aaaaggttgt caaaggtctt
   107821 ttccttttga cgactaaacc agttctttat gtagctaatg tggacgagga tgtggtttca
   107881 gaacctgact ctatcgacta tgtcaaacaa attcgtgaat ttgcagcgac agaaaatgct
   107941 gaagtagtcg ttatttctgc gcgtgctgag gaagaaattt ctgaattgga tgatgaagat
   108001 aaaaaagagt ttcttgaagc cattggtttg acagaatcag gtgtagataa gttgacgcgt
   108061 gcatcttacc acttgcttgg attgggaact tacttcacag ctggtgaaaa agaagttcgc
   108121 gcttggactt tcaaacgtgg tatgaaggct actcaagcag ctggtattat ccactcagac
   108181 tttgaaaaag gctttattcg tgcagtaacc atgtcatatg aagatctagt gaaatacgga
   108241 tctgaaaagg ccgtaaaaga agctggacgc ttgcgtgaag aaggaaaaga atatatcgtt
   108301 caagatggcg atatcatgga attccgcttt aatgtctaaa aattaataaa tggtgtcaat
   108361 taggttggaa aaaaattcca acccttttgg cttttgaaag gaaaaataaa tgaccaaatt
   108421 acttgtaggc ttgggaaatc caggggataa atattttgaa acaaaacaca atgttggttt
   108481 tatgttgatt gatcaactag cgaagaaaca gaatgtcact tttacacacg ataagatatt
   108541 tcaagctgac ctagcatcct ttttcctaaa tggagaaaaa atttatctgg ttaaaccaac
   108601 gacctttatg aatgaaagtg gaaaagcagt tcatgcttta ttaacttact atggtttgga
   108661 tattgacgat ttacttatca tttacgatga tcttgacatg gaagttggga aaattcgttt
   108721 aagagcaaaa ggctcagcag gtggtcataa tggtatcaag tctattattc aacatatagg
   108781 aactcaggtc tttaaccgtg ttaagattgg aattggaaga cctaaaaatg gtatgtcagt
   108841 tgttcatcat gttttgagta agtttgacag ggatgattat atcggtattt tacagtctgt
   108901 tgacaaagtt gacgattctg taaactacta tttacaagag aaaaattttg agaaaacaat
   108961 gcagaggtat aacggataaa tggtgacctt attagattta ttctcagaaa atgatcagat
   109021 taaaaaatgg catcaaaatt taacagataa gaaaagacaa ctaatacttg gtttatcaac
   109081 atctactaag gcgcttgcaa ttgcaagcag tttagaaaaa gaagatagga ttgtgttatt
   109141 gacgtcaact tatggagaag cagaaggact tgttagtgat cttatatcta tcttgggtga
   109201 ggaactcgtc tatccatttt tggtagatga tgctcctatg gtggagtttt tgatgtcttc
   109261 acaggaaaaa attatttcac gggttgaagc cttgcgtttt ttgactgatt catctaagaa
   109321 agggatttta gtttgtaata tcgcagcaag tcgattgatt ttaccgtctc ccaatgcatt
   109381 caaagatagt attgtaaaaa tctcagttgg tgaagaatat gatcaacacg cgtttatcca
   109441 tcagttaaag gaaaatggct atcgaaaagt tactcaagta caaactcagg gcgaatttag
   109501 tcttcgagga gatattttag atatttttga aatatcccag ttagaacctt gtcgaattga
   109561 gttttttggt gatgaaattg atggtatcag gtcatttgaa gtagaaacac aattatcgaa
   109621 agaaaataag acagaactca ctatctttcc agctagtgat atgcttttga gagaaaagga
   109681 ttatcaacga ggacagtcag ctttagaaaa acaaatttca aaaactttat cacctatttt
   109741 gaaatcatac ctagaagaaa ttctttcaag ttttcatcaa aagcaaagtc atgcagattc
   109801 tcggaagttt ttatctttgt gctatgataa gacatggact gtctttgatt atattgaaaa
   109861 agatactcca atattctttg atgattatca aaaattgatg aatcagtatg aagtatttga
   109921 aagagaatta gcgcagtact ttacagaaga attacagaat agtaaagcat tttctgatat
   109981 gcagtatttt tctgatattg aacaaatcta taaaaaacaa agtccagtga cctttttctc
   110041 taatcttcaa aagggtttag gaaatctcaa atttgacaaa atttatcaat tcaatcaata
   110101 tcctatgcag gaatttttca atcagttttc ttttctaaaa gaagaaattg aacgatataa
   110161 aaaaatggat tacaccatta ttctgcagtc tagcaattca atgggaagta aaacattgga
   110221 ggatatgtta gaggaatatc agattaaatt ggattctaga gataagacaa gtatctgtaa
   110281 agaatctgta aacttaatag agggtaatct cagacatggt tttcattttg tagatgaaaa
   110341 gattttattg ataactgaac atgagatttt tcaaaagaaa ttaaagcgtc gttttcgaag
   110401 acaacatgtt tcaaatgcag agagattaaa agattacaat gaacttgaaa aaggggacta
   110461 tgttgtccat catatccatg ggattggtca atatctagga attgaaacca ttgaaatcaa
   110521 gggaattcat cgcgattatg tcagtgtcca ataccaaaat ggtgatcaaa tttctattcc
   110581 cgtggaacag attcatctac tgtccaaata tatttcaagt gatggtaaag ttccaaaact
   110641 caataaatta aatgatggtc attttaaaaa ggccaagcaa aaggttaaga accaggtaga
   110701 ggatatagct gatgatttaa tcaaactcta ctctgaacgt agtcagttga agggttttgc
   110761 tttctcagct gatgatgatg atcaagatgc ctttgatgat gctttccctt atgttgaaac
   110821 ggatgatcaa cttcgtagta ttgaggaaat caagagggat atgcaggctt ctcacccaat
   110881 ggatcgactt ttagttgggg atgttggttt tggaaagact gaagttgcta tgcgtgcagc
   110941 ctttaaagca gtcaatgatc acaaacaggt tgtcattcta gttccgacga cggttttagc
   111001 gcaacagcac tatacgaatt ttaaggaacg attccaaaat tttgcagtta atgttgatgt
   111061 gttgagtcgc tttagaagta aaaaagagca gactgcaaca cttgaaaaat tgaaaaacgg
   111121 tcaagtcgat attttgattg gaacacatcg tgttttgtca aaagatgttg tgtttgctga
   111181 tttgggcttg atgattattg atgaggaaca gcgatttggt gtcaagcata aggaaacttt
   111241 gaaagaactg aagaaacaag tggatgtcct aaccttgacc gctacgccaa tccctcgtac
   111301 cctccatatg tctatgctgg gaatcagaga tttgtctgtt attgaaactc cgccgactaa
   111361 tcgctatcct gttcagacct atgttttgga aaagaatgat agtgtcattc gtgatgctgt
   111421 cttgcgtgaa atggagcgtg gaggtcaagt ttactatctt tacaacaaag ttgacacaat
   111481 tgttcagaag gtttcagaat tacaggagtt gattccggag gcttcgattg gatatgttca
   111541 tggtcgaatg agtgaagtcc agttggaaaa tactctatta gactttattg agggacaata
   111601 cgatatcttg gtgacgacta ctattattga gacaggggtg gacattccaa atgctaatac
   111661 tttatttatt gaaaatgcgg accatatggg cttgtcaacc ttatatcagt taagaggaag
   111721 agtcggtcgt agtaatcgta ttgcttatgc ttatctcatg tatcgtccag aaaaatcaat
   111781 cagtgaagtc tctgaaaaga gattagaagc gattaaagga tttacagaat tgggctctgg
   111841 ctttaagatt gcaatgcgag atctttcgat tcgtggagca ggaaatcttt taggaaaatc
   111901 ccagtctggt ttcattgatt ctgttggttt tgaattgtat tcgcagttat tagaggaagc
   111961 tattgctaaa cgaaacggta atgctaacgc taacacaaga accaaaggga atgctgagtt
   112021 gattttgcaa attgatgcct atcttcctga tacttatatt tctgatcaac gacataagat
   112081 tgaaatttac aagaaaattc gtcaaattga caaccgtgtc aattatgaag agttacaaga
   112141 ggagttgata gaccgttttg gagaataccc agatgtagta gcctatctgt tagagattgg
   112201 tttggtcaaa tcatgcttgg acaaggtctt tgttcaacgt gtggaaagaa aagataataa
   112261 aattacaatt caatttgaaa aagtcactca acgactgttt ttagctcaag attattttaa
   112321 agctttatcc gtaacgaact taaaagcagg catcgttgag aataagggat taatggagct
   112381 tgtatttgat gtccaaaata agaaagatta tgaaatttta gaaggtttgc tgatttttgg
   112441 agaaagttta ttagagataa aagagtctaa ggaagaaaat tccatttgat atttttcttc
   112501 tataaaatag ataaaaatgg tacaataata aattgaggta ataaggatga gattagataa
   112561 atatttaaaa gtatcgcgaa ttatcaagcg tcgtacagtc gcaaaggaag tagcagataa
   112621 aggtagaatc aaggttaatg gaatcttggc caaaagttca acggacttga aagttaatga
   112681 ccaagttgaa attcgctttg gcaataagtt gctgcttgta aaagtactag agatgaaaga
   112741 tagtacaaaa aaagaagatg cagcaggcat gtatgaaatt atcagtgaaa cacgggtaga
   112801 agaaaatgtc taaaaatatt gtacaattga ataattcttt tattcaaaat gaataccaac
   112861 gtcgtcgcta cctgatgaaa gaacgacaaa aacggaatcg ttttatgggg ggggtattga
   112921 ttttgattat gctattattt atcttgccaa cttttaattt agcgcagagt tatcagcaat
   112981 tactccaaag acgtcagcaa ttagcagact tgcaaactca gtatcaaact ttgagtgatg
   113041 aaaaggataa ggaaacagca tttgctacca agttgaaaga tgaagattat gctgctaaat
   113101 atacacgagc gaagtactat tattctaagt cgagggaaaa agtttatacg attcctgact
   113161 tgcttcaaag gtgataaaat ggaaaattta ttagacgtaa tagagcaatt tttgagtttg
   113221 tcagatgaaa agctggaaga attggctgat aaaaatcaat tattgcgttt acaagaagaa
   113281 aaggaaagga agaatgcgta aattcttaat tattttgttg ctaccaagtt ttttgaccat
   113341 ttcaaaagtc gttagcacag aaaaagaagt cgtctatact tcgaaagaaa tttattacct
   113401 ttcacaatct gactttggta tttattttag agaaaaatta agttctccca tggtttatgg
   113461 agaggttcct gtttatgcga atgaagattt agtagtggaa tctgggaaat tgactcccaa
   113521 aataagtttt caaataaccg agtggcgctt aaataaacaa ggaattccag tatttaagct
   113581 atcaaatcat caatttatag ctgcggacaa acgattttta tatgatcaat cagaggtaac
   113641 tccaacaata aaaaaagtat ggttagaatc tgactttaaa ctgtacaata gtccttatga
   113701 tttaaaagaa gtgaaatcat ccttatcagc ttattcgcaa gtatcaatcg acaagaccat
   113761 gtttgtagaa ggaagagaat ttctacatat tgatcaggct ggatgggtag ctaaagaatc
   113821 aacttctgaa gaagataatc ggatgagtaa agttcaagaa atgttatctg aaaaatatca
   113881 gaaagattct ttctctattt atgttaagca actgactact ggaaaagaag ctggtatcaa
   113941 tcaagatgaa aagatgtatg cagccagcgt tttgaaactc tcctatctct attatacgca
   114001 agaaaaaata aatgagggtc tttatcagtt agatacgact gtaaaatacg tatctgcagt
   114061 caatgatttt ccaggttctt ataaaccaga gggaagtggt agtcttccta aaaaagaaga
   114121 taataaagaa tattctttaa aggatttaat tacgaaagta tcaaaagaat ctgataatgt
   114181 agctcataat ctattgggat attacatttc aaaccaatct gatgccacat tcaaatccaa
   114241 gatgtctgcc attatgggag atgattggga tccaaaagaa aaattgattt cttctaagat
   114301 ggccgggaag tttatggaag ctatttataa tcaaaatgga tttgtgctag agtctttgac
   114361 taaaacagat tttgatagtc agcgaattgc caaaggtgtt tctgttaaag tagctcataa
   114421 aattggagat gcggatgaat ttaagcatga tacgggtgtt gtctatgcag attctccatt
   114481 tattctttct attttcacta agaattctga ttatgatacg atttctaaga tagccaagga
   114541 tgtttatgag gttctaaaat gagggaacca gattttttaa atcattttct caagaaggga
   114601 tatttcaaaa agcatgctaa ggcggttcta gctctttctg gtggattaga ttccatgttt
   114661 ctatttaagg tattgtctac ttatcaaaaa gagttagaga ttgaattgat tctagctcat
   114721 gtgaatcata agcagagaat tgaatcagat tgggaagaaa aggaattaag gaagttggct
   114781 gctgaagcag agcttcctat ttatatcagc aatttttcag gagaattttc agaagcgcgt
   114841 gcacgaaatt ttcgttatga tttttttcaa gaggtcatga aaaagacagg tgcgacagct
   114901 ttagtcactg cccaccatgc tgatgatcag gtggaaacga ttttgatgcg cttgattcga
   114961 ggaactcgct tgcgctatct atcaggaatt aaggagaagc aagtagtcgg agagatagaa
   115021 atcattcgtc ccttcttgca ttttaagaaa aaagactttc catcaatttt tcactttgaa
   115081 gatacatcaa atcaggagaa tcattatttt cgaaatcgta ttcgaaattc ttacttacca
   115141 gaattggaaa aagaaaatcc tcgatttagg aatgcaatct taggcattag caatgaaatt
   115201 ttagattatg atttggcaat agctgaatta tctaacaata ttaatgtgga agatttacag
   115261 cagttatttt cttattctga gtctacacaa agagttttac ttcaaactta tctgaatcgt
   115321 tttccagatt tgaatcttac aaaagctcag tttgctgaag ttcagcagat tttaaaatct
   115381 aaaagccagt atcgtcatcc gattaaaaat ggctatgaat tgataaaaga gtaccaacag
   115441 tttcagattt gtaaaatcag tccgcaggct gatgaagagg aagatgaact tgtgttacac
   115501 tatcaaaatc aggtagctta tcaaggatat ttattttcct ttggacttcc attagaaggt
   115561 gaatcaattc aacaaatacc tgtttcacgt gaaacatcca tacacattcg tcatcgaaaa
   115621 acaggagatg ttttgattca aaatgggcat agaaaaaaac tcagacgttt atttattgat
   115681 ttgaaaatcc ctatggaaaa gagaaactct gctcttatta ttgagcaatt tggtgaaatt
   115741 gtctcaattt tgggaattgc gaccaataat ttgagtaaaa aaacgaaaaa tgatataatg
   115801 aacactgtac tttatataga aaaaatagat aggtaaaaaa tgttagaaaa cgatattaaa
   115861 aaagtcctcg tttcacacga tgaaattaca gaagcagcta aaaaactagg tgctcaatta
   115921 actaaagact atgcaggaaa aaatccaatc ttagttggga ttttaaaagg atctattcct
   115981 tttatggctg aattggtcaa acatattgat acacatattg aaatggactt catgatggtt
   116041 tctagctacc atggtggaac agcaagtagt ggtgttatca atattaaaca agatgtgact
   116101 caagatatca aaggaagaca tgttctattt gtagaagata tcattgatac aggtcaaact
   116161 ttgaagaatt tgcgagatat gtttaaagaa agagaagcag cttctgttaa aattgcaacc
   116221 ttgttggata aaccagaagg acgtgttgta gaaattgagg cagactatac ctgctttact
   116281 atcccaaatg agtttgtagt aggttatggt ttagactaca aagaaaatta tcgtaatctt
   116341 ccttatattg gagtattgaa agaggaagtg tattcaaatt agaaagaata atctttaatg
   116401 aaaaaacaaa ataatggttt aattaaaaat ccttttctat ggttattatt tatctttttc
   116461 cttgtgacag gattccagta tttctattct gggaataact caggaggaag tcagcaaatc
   116521 aactatactg agttggtaca agaaattacc gatggtaatg taaaagaatt aacttaccaa
   116581 ccaaatggta gtgttatcga agtttctggt gtctataaaa atcctaaaac aagtaaagaa
   116641 ggaacaggta ttcagttttt cacgccatct gttactaagg tagagaaatt taccagcact
   116701 attcttcctg cagatactac cgtatcagaa ttgcaaaaac ttgctactga ccataaagca
   116761 gaagtaactg ttaagcatga aagttcaagt ggtatatgga ttaatctact cgtatccatt
   116821 gtgccatttg gaattctatt cttcttccta ttctctatga tgggaaatat gggaggaggc
   116881 aatggccgta atccaatgag ttttggacgt agtaaggcta aagcagcaaa taaagaagat
   116941 attaaagtaa gattttcaga tgttgctgga gctgaggaag aaaaacaaga actagttgaa
   117001 gttgttgagt tcttaaaaga tccaaaacga ttcacaaaac ttggagcccg tattccagca
   117061 ggtgttcttt tggagggacc tccggggaca ggtaagactt tgcttgctaa ggcagtcgct
   117121 ggagaagcag gtgttccatt ctttagtatc tcaggttctg actttgtaga aatgtttgtc
   117181 ggagttggag ctagtcgtgt tcgctctctt tttgaggatg ccaaaaaagc agcaccagct
   117241 atcatcttta tcgatgaaat tgatgctgtt ggacgtcaac gtggagtcgg tctcggcgga
   117301 ggtaatgacg aacgtgaaca aaccttgaac caacttttga ttgagatgga tggttttgag
   117361 ggaaatgaag ggattatcgt catcgctgcg acaaaccgtt cagatgtact tgatcctgcc
   117421 cttttgcgtc caggacgttt tgatagaaaa gtattggttg gccgtcctga tgttaaaggt
   117481 cgtgaagcaa tcttgaaagt tcacgctaag aacaagcctt tagcagaaga tgttgatttg
   117541 aaattagtgg ctcaacaaac tccaggcttt gttggtgctg atttagagaa tgtcttgaat
   117601 gaagcagctt tagttgctgc tcgtcgcaat aaatcgataa ttgatgcttc agatattgat
   117661 gaagcagaag atagagttat tgctggacct tctaagaaag ataagacagt ttcacaaaaa
   117721 gaacgagaat tggttgctta ccatgaggca ggacatacca ttgttggtct agtcttgtcg
   117781 aatgctcgcg ttgtccataa ggttacaatt gtaccacgcg gccgtgcagg cggatacatg
   117841 attgcacttc ctaaagagga tcaaatgctt ctatctaaag aagatatgaa agagcaattg
   117901 gctggcttaa tgggtggacg tgtagctgaa gaaattatct ttaatgtcca aactacagga
   117961 gcttcaaacg actttgaaca agcgacacaa atggcacgtg caatggttac agagtacggt
   118021 atgagtgaaa aacttggccc agtacaatat gaaggaaacc atgctatgct tggtgcacag
   118081 agtcctcaaa aatcaatttc agaacaaaca gcttatgaaa ttgatgaaga ggttcgttca
   118141 ttattaaatg aggcacgaaa taaagctgct gaaattattc agtcaaatcg tgaaactcac
   118201 aagttaattg cagaagcatt attgaaatac gaaacattgg atagtacaca aattaaagct
   118261 ctttacgaaa caggaaagat gcctgaagca gtagaagagg aatctcatgc actatcctat
   118321 gatgaagtaa agtcaaaaat gaatgacgaa a
//
LOCUS       DBJKQU010000002        88152 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.002, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000002 DBJKQU010000000
VERSION     DBJKQU010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 88152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88152
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.002"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            13..1236
                     /locus_tag="ACSUUC_000108"
     CDS             13..1236
                     /locus_tag="ACSUUC_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HHQ8053415.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            2668..2952
                     /locus_tag="ACSUUC_000109"
     CDS             2668..2952
                     /locus_tag="ACSUUC_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053416.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            3279..3497
                     /locus_tag="ACSUUC_000110"
     CDS             3279..3497
                     /locus_tag="ACSUUC_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053417.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(3864..6188)
                     /gene="pflB"
                     /locus_tag="ACSUUC_000111"
     CDS             complement(3864..6188)
                     /gene="pflB"
                     /locus_tag="ACSUUC_000111"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HHQ8053418.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            6536..7597
                     /gene="dinB"
                     /locus_tag="ACSUUC_000112"
     CDS             6536..7597
                     /gene="dinB"
                     /locus_tag="ACSUUC_000112"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HHQ8053419.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(7744..8589)
                     /locus_tag="ACSUUC_000113"
     CDS             complement(7744..8589)
                     /locus_tag="ACSUUC_000113"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HHQ8053420.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(8620..8757)
                     /locus_tag="ACSUUC_000114"
     CDS             complement(8620..8757)
                     /locus_tag="ACSUUC_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053421.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            8844..9970
                     /locus_tag="ACSUUC_000115"
                     /pseudo
     CDS             8844..9970
                     /locus_tag="ACSUUC_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857010.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(10164..12053)
                     /locus_tag="ACSUUC_000116"
     CDS             complement(10164..12053)
                     /locus_tag="ACSUUC_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 family protein"
                     /protein_id="HHQ8053422.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            12191..13756
                     /locus_tag="ACSUUC_000117"
     CDS             12191..13756
                     /locus_tag="ACSUUC_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HHQ8053423.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            13756..14520
                     /locus_tag="ACSUUC_000118"
     CDS             13756..14520
                     /locus_tag="ACSUUC_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053424.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(14719..14934)
                     /locus_tag="ACSUUC_000119"
     CDS             complement(14719..14934)
                     /locus_tag="ACSUUC_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053425.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(15805..17055)
                     /gene="ilvA"
                     /locus_tag="ACSUUC_000120"
     CDS             complement(15805..17055)
                     /gene="ilvA"
                     /locus_tag="ACSUUC_000120"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HHQ8053426.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(17105..17461)
                     /locus_tag="ACSUUC_000121"
     CDS             complement(17105..17461)
                     /locus_tag="ACSUUC_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HHQ8053427.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(17699..17935)
                     /locus_tag="ACSUUC_000122"
     CDS             complement(17699..17935)
                     /locus_tag="ACSUUC_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053428.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(18042..19064)
                     /gene="ilvC"
                     /locus_tag="ACSUUC_000123"
     CDS             complement(18042..19064)
                     /gene="ilvC"
                     /locus_tag="ACSUUC_000123"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HHQ8053429.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(19130..19606)
                     /gene="ilvN"
                     /locus_tag="ACSUUC_000124"
     CDS             complement(19130..19606)
                     /gene="ilvN"
                     /locus_tag="ACSUUC_000124"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HHQ8053430.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(19599..21299)
                     /locus_tag="ACSUUC_000125"
     CDS             complement(19599..21299)
                     /locus_tag="ACSUUC_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HHQ8053431.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(21500..23167)
                     /locus_tag="ACSUUC_000126"
     CDS             complement(21500..23167)
                     /locus_tag="ACSUUC_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HHQ8053432.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(23170..23535)
                     /locus_tag="ACSUUC_000127"
     CDS             complement(23170..23535)
                     /locus_tag="ACSUUC_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HHQ8053433.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(23692..23880)
                     /gene="rpmB"
                     /locus_tag="ACSUUC_000128"
     CDS             complement(23692..23880)
                     /gene="rpmB"
                     /locus_tag="ACSUUC_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HHQ8053434.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(23996..24172)
                     /locus_tag="ACSUUC_000129"
     CDS             complement(23996..24172)
                     /locus_tag="ACSUUC_000129"
                     /inference="COORDINATES: protein motif:HMM:NF013652.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHQ8053435.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(24283..24480)
                     /locus_tag="ACSUUC_000130"
     CDS             complement(24283..24480)
                     /locus_tag="ACSUUC_000130"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053436.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(24908..26452)
                     /locus_tag="ACSUUC_000131"
     CDS             complement(24908..26452)
                     /locus_tag="ACSUUC_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HHQ8053437.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLELLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            26665..26967
                     /gene="gatC"
                     /locus_tag="ACSUUC_000132"
     CDS             26665..26967
                     /gene="gatC"
                     /locus_tag="ACSUUC_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HHQ8053438.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGIDRDRLFKNVPEKDNYYIKVPAILDNGGDA"
     gene            26967..28433
                     /gene="gatA"
                     /locus_tag="ACSUUC_000133"
     CDS             26967..28433
                     /gene="gatA"
                     /locus_tag="ACSUUC_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HHQ8053439.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAHVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TIQSAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNYDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            28433..29875
                     /gene="gatB"
                     /locus_tag="ACSUUC_000134"
     CDS             28433..29875
                     /gene="gatB"
                     /locus_tag="ACSUUC_000134"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HHQ8053440.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEIQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEIAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            30004..30564
                     /gene="efp"
                     /locus_tag="ACSUUC_000135"
     CDS             30004..30564
                     /gene="efp"
                     /locus_tag="ACSUUC_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HHQ8053441.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            30586..30975
                     /locus_tag="ACSUUC_000136"
     CDS             30586..30975
                     /locus_tag="ACSUUC_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HHQ8053442.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            30968..31390
                     /gene="nusB"
                     /locus_tag="ACSUUC_000137"
     CDS             30968..31390
                     /gene="nusB"
                     /locus_tag="ACSUUC_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HHQ8053443.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(31440..31676)
                     /locus_tag="ACSUUC_000138"
     CDS             complement(31440..31676)
                     /locus_tag="ACSUUC_000138"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HHQ8053444.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(31689..32163)
                     /locus_tag="ACSUUC_000139"
                     /pseudo
     CDS             complement(31689..32163)
                     /locus_tag="ACSUUC_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(32181..32366)
                     /gene="briC"
                     /locus_tag="ACSUUC_000140"
     CDS             complement(32181..32366)
                     /gene="briC"
                     /locus_tag="ACSUUC_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HHQ8053445.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(32525..33292)
                     /locus_tag="ACSUUC_000141"
     CDS             complement(32525..33292)
                     /locus_tag="ACSUUC_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HHQ8053446.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(33289..34155)
                     /gene="accD"
                     /locus_tag="ACSUUC_000142"
     CDS             complement(33289..34155)
                     /gene="accD"
                     /locus_tag="ACSUUC_000142"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HHQ8053447.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(34192..35559)
                     /gene="accC"
                     /locus_tag="ACSUUC_000143"
     CDS             complement(34192..35559)
                     /gene="accC"
                     /locus_tag="ACSUUC_000143"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HHQ8053448.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(35571..35993)
                     /gene="fabZ"
                     /locus_tag="ACSUUC_000144"
     CDS             complement(35571..35993)
                     /gene="fabZ"
                     /locus_tag="ACSUUC_000144"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HHQ8053449.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(35990..36475)
                     /gene="accB"
                     /locus_tag="ACSUUC_000145"
     CDS             complement(35990..36475)
                     /gene="accB"
                     /locus_tag="ACSUUC_000145"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HHQ8053450.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(36478..37713)
                     /gene="fabF"
                     /locus_tag="ACSUUC_000146"
     CDS             complement(36478..37713)
                     /gene="fabF"
                     /locus_tag="ACSUUC_000146"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HHQ8053451.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(37735..38466)
                     /gene="fabG"
                     /locus_tag="ACSUUC_000147"
     CDS             complement(37735..38466)
                     /gene="fabG"
                     /locus_tag="ACSUUC_000147"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HHQ8053452.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(38500..39420)
                     /gene="fabD"
                     /locus_tag="ACSUUC_000148"
     CDS             complement(38500..39420)
                     /gene="fabD"
                     /locus_tag="ACSUUC_000148"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HHQ8053453.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(39413..40387)
                     /gene="fabK"
                     /locus_tag="ACSUUC_000149"
     CDS             complement(39413..40387)
                     /gene="fabK"
                     /locus_tag="ACSUUC_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HHQ8053454.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(40506..40730)
                     /locus_tag="ACSUUC_000150"
     CDS             complement(40506..40730)
                     /locus_tag="ACSUUC_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HHQ8053455.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(40790..41764)
                     /locus_tag="ACSUUC_000151"
     CDS             complement(40790..41764)
                     /locus_tag="ACSUUC_000151"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HHQ8053456.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(41764..42198)
                     /locus_tag="ACSUUC_000152"
     CDS             complement(41764..42198)
                     /locus_tag="ACSUUC_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHQ8053457.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(42292..43077)
                     /locus_tag="ACSUUC_000153"
     CDS             complement(42292..43077)
                     /locus_tag="ACSUUC_000153"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HHQ8053458.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            43402..44766
                     /locus_tag="ACSUUC_000154"
     CDS             43402..44766
                     /locus_tag="ACSUUC_000154"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HHQ8053459.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            44769..45140
                     /locus_tag="ACSUUC_000155"
     CDS             44769..45140
                     /locus_tag="ACSUUC_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HHQ8053460.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            45354..46628
                     /gene="serS"
                     /locus_tag="ACSUUC_000156"
     CDS             45354..46628
                     /gene="serS"
                     /locus_tag="ACSUUC_000156"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HHQ8053461.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDTKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(46653..47552)
                     /locus_tag="ACSUUC_000157"
     CDS             complement(46653..47552)
                     /locus_tag="ACSUUC_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HHQ8053462.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(47662..48210)
                     /locus_tag="ACSUUC_000158"
     CDS             complement(47662..48210)
                     /locus_tag="ACSUUC_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HHQ8053463.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(48428..49750)
                     /locus_tag="ACSUUC_000159"
     CDS             complement(48428..49750)
                     /locus_tag="ACSUUC_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HHQ8053464.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(49841..49929)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(50093..52429)
                     /locus_tag="ACSUUC_000160"
     CDS             complement(50093..52429)
                     /locus_tag="ACSUUC_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0045910 - negative regulation of DNA
                     recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HHQ8053465.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEKLARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDIFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(52533..53081)
                     /locus_tag="ACSUUC_000161"
     CDS             complement(52533..53081)
                     /locus_tag="ACSUUC_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HHQ8053466.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(53078..53380)
                     /gene="zapA"
                     /locus_tag="ACSUUC_000162"
     CDS             complement(53078..53380)
                     /gene="zapA"
                     /locus_tag="ACSUUC_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HHQ8053467.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            53467..54348
                     /gene="rnhC"
                     /locus_tag="ACSUUC_000163"
     CDS             53467..54348
                     /gene="rnhC"
                     /locus_tag="ACSUUC_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HHQ8053468.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEKKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            54352..54966
                     /gene="lepB"
                     /locus_tag="ACSUUC_000164"
     CDS             54352..54966
                     /gene="lepB"
                     /locus_tag="ACSUUC_000164"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HHQ8053469.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            55245..57611
                     /gene="recD2"
                     /locus_tag="ACSUUC_000165"
     CDS             55245..57611
                     /gene="recD2"
                     /locus_tag="ACSUUC_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SF1B family DNA helicase RecD2"
                     /protein_id="HHQ8053470.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTHLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(57659..58942)
                     /gene="tig"
                     /locus_tag="ACSUUC_000166"
     CDS             complement(57659..58942)
                     /gene="tig"
                     /locus_tag="ACSUUC_000166"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HHQ8053471.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(59136..59495)
                     /locus_tag="ACSUUC_000167"
     CDS             complement(59136..59495)
                     /locus_tag="ACSUUC_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHQ8053472.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(59797..60387)
                     /gene="cbpG"
                     /locus_tag="ACSUUC_000168"
                     /pseudo
     CDS             complement(59797..60387)
                     /gene="cbpG"
                     /locus_tag="ACSUUC_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            complement(60468..60707)
                     /locus_tag="ACSUUC_000169"
     CDS             complement(60468..60707)
                     /locus_tag="ACSUUC_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053473.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(60857..61399)
                     /locus_tag="ACSUUC_000170"
                     /pseudo
     CDS             complement(60857..61399)
                     /locus_tag="ACSUUC_000170"
                     /inference="COORDINATES: protein motif:HMM:NF020296.6"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(61381..61623)
                     /locus_tag="ACSUUC_000171"
     CDS             complement(61381..61623)
                     /locus_tag="ACSUUC_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HHQ8053474.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(61624..62256)
                     /locus_tag="ACSUUC_000172"
     CDS             complement(61624..62256)
                     /locus_tag="ACSUUC_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHQ8053475.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(62270..63265)
                     /locus_tag="ACSUUC_000173"
     CDS             complement(62270..63265)
                     /locus_tag="ACSUUC_000173"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHQ8053476.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHIILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(63262..63960)
                     /gene="liaF"
                     /locus_tag="ACSUUC_000174"
     CDS             complement(63262..63960)
                     /gene="liaF"
                     /locus_tag="ACSUUC_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HHQ8053477.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKNYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(64038..65048)
                     /gene="fni"
                     /locus_tag="ACSUUC_000175"
     CDS             complement(64038..65048)
                     /gene="fni"
                     /locus_tag="ACSUUC_000175"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HHQ8053478.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLHTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVLGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(65032..66039)
                     /locus_tag="ACSUUC_000176"
     CDS             complement(65032..66039)
                     /locus_tag="ACSUUC_000176"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HHQ8053479.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(66026..66979)
                     /gene="mvaD"
                     /locus_tag="ACSUUC_000177"
     CDS             complement(66026..66979)
                     /gene="mvaD"
                     /locus_tag="ACSUUC_000177"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HHQ8053480.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            complement(66961..67839)
                     /gene="mvk"
                     /locus_tag="ACSUUC_000178"
     CDS             complement(66961..67839)
                     /gene="mvk"
                     /locus_tag="ACSUUC_000178"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HHQ8053481.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(67961..68977)
                     /gene="cbpC"
                     /locus_tag="ACSUUC_000179"
     CDS             complement(67961..68977)
                     /gene="cbpC"
                     /locus_tag="ACSUUC_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HHQ8053482.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGLTWYYLNAGNGDMKTGWFQVNGKWYYAYSSGALAVNTTVDGYSVNYNG
                     EWVQ"
     gene            complement(69075..69764)
                     /locus_tag="ACSUUC_000180"
     CDS             complement(69075..69764)
                     /locus_tag="ACSUUC_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHQ8053483.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(69776..71200)
                     /gene="gndA"
                     /locus_tag="ACSUUC_000181"
     CDS             complement(69776..71200)
                     /gene="gndA"
                     /locus_tag="ACSUUC_000181"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HHQ8053484.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(71276..72670)
                     /gene="mapZ"
                     /locus_tag="ACSUUC_000182"
     CDS             complement(71276..72670)
                     /gene="mapZ"
                     /locus_tag="ACSUUC_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ"
                     /protein_id="HHQ8053485.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSLSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(72682..73839)
                     /locus_tag="ACSUUC_000183"
     CDS             complement(72682..73839)
                     /locus_tag="ACSUUC_000183"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="THUMP domain-containing class I SAM-dependent
                     RNA methyltransferase"
                     /protein_id="HHQ8053486.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(73924..74304)
                     /gene="rnpB"
                     /locus_tag="ACSUUC_000184"
     ncRNA           complement(73924..74304)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACSUUC_000184"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(74325..74654)
                     /gene="gpsB"
                     /locus_tag="ACSUUC_000185"
     CDS             complement(74325..74654)
                     /gene="gpsB"
                     /locus_tag="ACSUUC_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HHQ8053487.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(74724..75251)
                     /locus_tag="ACSUUC_000186"
     CDS             complement(74724..75251)
                     /locus_tag="ACSUUC_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HHQ8053488.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            75317..75913
                     /gene="recU"
                     /locus_tag="ACSUUC_000187"
     CDS             75317..75913
                     /gene="recU"
                     /locus_tag="ACSUUC_000187"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HHQ8053489.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            75910..78069
                     /gene="pbp1a"
                     /locus_tag="ACSUUC_000188"
     CDS             75910..78069
                     /gene="pbp1a"
                     /locus_tag="ACSUUC_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HHQ8053490.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAA
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(78236..83539)
                     /locus_tag="ACSUUC_000189"
     CDS             complement(78236..83539)
                     /locus_tag="ACSUUC_000189"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HHQ8053491.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTASTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSIKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HSRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKLVVTRKSNDVNSPLYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYSFVVGKGEFQSGRRGTQASNLEIHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FESLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(83839..85821)
                     /locus_tag="ACSUUC_000190"
     CDS             complement(83839..85821)
                     /locus_tag="ACSUUC_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HHQ8053492.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVDLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMIPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            complement(86397..87635)
                     /locus_tag="ACSUUC_000191"
     CDS             complement(86397..87635)
                     /locus_tag="ACSUUC_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HHQ8053493.1"
                     /translation="MKIAVTGTGYVGLSIAVLLAQHHQVIAVDIIPEKVELINQRKSP
                     IQDDYIEKYLAEKDLNLVATLDAKEAYKDADFVVIAAPTNYDPKKNFFDTSAVESVIE
                     TVLKYNPDAIMVIKSTVPVGYTESARKKFQTENILFSPEFLRESKALYDNLYPSRIIL
                     GTDKNNERLVSVAETFAGLLQEGALKEDIDTLYMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDVPE
                     ELIGAIVRSNSTRKDFIADQVLKMVDYYDYSAHNVFNERVEKDIIIGIYRLTMKSNSD
                     NFRQSSIQGIMKRIKAKGVRVVIYEPTLESGSTFFGSSIINDLEEFKRLSNAIVANRY
                     DNSLEDVKEKVYTRDIFERD"
     gene            complement(87704..>88152)
                     /gene="cap8K"
                     /locus_tag="ACSUUC_000192"
     CDS             complement(87704..>88152)
                     /gene="cap8K"
                     /locus_tag="ACSUUC_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="polysaccharide polymerase Cap8K"
                     /protein_id="HHQ8053494.1"
                     /translation="ISTFLGVLAFQFYPSNNKFSIFIDNILTGRIKLAAYARTFFGYT
                     FWGQYVDKEIVWDPIWGLTSFTFDSFYSFLMSNAGIIWLLILSVLFVKLQKYLDNKSL
                     ILLLAWSMYAVTETDLIFPSYGFQFLFLSILFTNTSTCSTIMLKNN"
BASE COUNT        26138 a        19731 c        16173 g        26110 t
ORIGIN      
        1 aggaggaaac aaatgattac aaaacaatca gcctttttac aaaatagagc cactatactg
       61 gagtttctat atcgaaatcc agcaacatcc cgtacagata ttgttaatga aacaggactt
      121 actccagcaa caacgactaa catcataaaa gagctaagcg aacagtccct catatacgaa
      181 actggtgatg aatttagcga gttttccgga tctggaagac gtagaaaaac tatttctatc
      241 acagataata ttccgtatgt tgttggaggt attgaaataa acgtcctagg tatctttctc
      301 agtctatgtg acttacaagg gaaaactctt ttcgagacag aaattttgaa tgaagattat
      361 cctatttcag aaatcaattc caccattacc aatatgataa aaacagctat agagtacgtc
      421 cctttggaaa caaaattact tggatttggc ttatcaatac ctggacatta taacaaagac
      481 tccggaagta tcattacaaa caaccccata tgggaatctt ttaatttatt aaatgtaatt
      541 aaaagattca attttccttt tattgtaaaa aataatatcg attgtatggc tataggacaa
      601 taccttttta atccacacaa tacccccgat aactttattt tcctacacgc tggattaggt
      661 atttacactt cctttttcac aaaagaaaaa ataggagcct ctaaaaatcc ttatatcgga
      721 gaaattggac acaccattgt cgaattgaat gggcaatatt gtgaatgcgg aaaaaaaggt
      781 tgtttacaaa catatatttc ggatgcttgg ttaatcaaac acgcccaatt attatttaaa
      841 aattcccaac taactgtact aaaaagcctt gtaaagactg aaaaagacat tcatttagac
      901 acccttttaa cggcttataa tttaggcgac tccgctttac gtcaacaaat tgataaagga
      961 gtcaatttat tagccacttc tattgcaaat ctcctcctca tcaatcctgc tgataaaatc
     1021 tatatcaaca gtcaattgct taattatcaa cctttcactc atgaagtcag ggataaaatc
     1081 caagaccagc tccacttcgt tccctttact cgtaatatag aaattgaaat tttaccttac
     1141 aacaaacatc gtggaagtat aggagcttgt gcattagcta tcgtcgcttt tttcatagaa
     1201 catagcaatg tattacaaga tattatttca ccttaatata ttagaaatct atagacctgt
     1261 ttaaatcaac tataacctgt agtagatatc tcgtatttag acaatatgaa aacaagacga
     1321 cttccatata ggaaaccgcc ttctctctat gttgagtgat ttatattaaa ataacttttc
     1381 ttctagctgc attttattat tataaaaaca ttcatcataa ccctgaactt aaataacgat
     1441 ttttattcaa gatacatact cctagaataa actttatatg aaattctcat ttttgttttt
     1501 acaattctcc ttagttaaat cttgtttaat atatgtttta catatagtat ttagcgccac
     1561 atagtactga actctctcca aaaacggtta ttcctctttg aatagggcgt tatcacaaga
     1621 aaagcatctc cacgtttcaa cttcatatgg ctcaaaaaca atcaattgat gctaaaacct
     1681 gtacctagat gtttcggttc ataaaaccat gaaactgtaa aagtggatga aattgatagc
     1741 gatagtcaaa tcaagaggca tcataactct aaaaagtcac aatatataag ttcatcctcg
     1801 gaaaaatatc attctaattg ttgaaatgcc tacatgaaaa gaaacgtcaa atgctcatga
     1861 aacaacgaat acaggtatca aaactatgac aaaacaagtc cctaaattta ctaaagacac
     1921 tgctcaactt tacacctgta aatggttgtt gtataataaa gttacaaaga tgtacgacca
     1981 cactgttgta aatcatagtg ttcgcgaata tattactgat agcatttcta caaatacaat
     2041 tgaagagact ggatagactt taaacgaaat atgtcagtgt tttggcattc ctagccttca
     2101 tatcatttaa agaattctat agacaaaatt tttcccaata cagacactcg taacaactgc
     2161 ttcatttttc taccaacata tttaggaaca ggataagata gaagaagatt aatccatagc
     2221 tcagttctat accaatctaa gacaaataag ctaaaaaaac gattgataat aagcaaatag
     2281 attccaaatt ttctctatct gctcatttta ataaacaata ctagtgtaac tatccttcca
     2341 gtcagaaact tgtcaaatca caccgaaaac tcttctaaaa tttatctcgt taggcaatca
     2401 agcaaaaact cgacgatagt acaaacatta tcatacagaa ttgactgcct aaattatata
     2461 ctttagtaag gttttcggat aagaaaaaag gttcatttta catttctaaa cattcttttc
     2521 taagatgaaa aacagaattt ttcgattgtg atttaaagca acaagaagat tttcagtatc
     2581 atcctataga tacgagctaa ttaagaaaaa ctacattttt gaatataaac tacaataata
     2641 taaactaaat tttataggag gaagacaatg gattggtacg attatatgat acaggcatcc
     2701 aaacaatcac aattcaacgc aagccattgg tttcgctatt tgcgaaaagt tatttttgaa
     2761 gactattctt atttaacaaa ccaagatgta gaaaagttgc tagactccaa agaactaacc
     2821 cgttttcaaa aaattagctt gaagtatgcc tttcaagagc atactccaac tcataaatat
     2881 gtgatttcat taaataaacc tgctaagtta accaatgttc aaaaattgat ggagaaatac
     2941 aaacatggat aaaatgaaac cggtcttcca agccctaaat aagaaattaa ttcaggaaaa
     3001 tctgacttta acaattatgg ttatgtctta gaatatcatg gtttacgtgc cacacaagat
     3061 gttgatgctt tttatgacca aaatcagaaa atcaatgaaa ttattgctcg tgtaggaaaa
     3121 cagtttaatc ttaacatcca cgaagagtta tggctcaaca atcatgttgc aaagcaaata
     3181 tgaacaaaca acctccctta agtttatgcg aatccttgta ctcatttgag aatctgaccg
     3241 ttttagtagt ccctattgag tatgtgttag gaatgaagat gatgagtatc agagagcagg
     3301 atttgcaaga tattggtgca attattaaat acaaaaactt tcattcacca ttcgatacct
     3361 ttaaatattt aaaagacatg ggatttgata ctattgacct ctctgttcta ttagaaggtt
     3421 ttagttatgc ttatggtatg gattggttag aaaaattttt taaagaaaat caagataaac
     3481 ttcgcgaatt ttattaacag tatcaaacaa gatgattgtc aattagccag tcatcttatt
     3541 tttatgatga aatgaaataa aatcggaaca aatcacttag agaattccag tcaatttcta
     3601 gcactgtttg agccgtttca gcggactata gtaaaatgaa ataagaatag gacaaatcga
     3661 tcaggacagt caaatcgatt tctaagaatg ttttagaagt aaaggtgtac tattctagtt
     3721 tcaatctatt atatttcaga ttcggtccac tattccttcc caaaaacatt gcatattgcg
     3781 ccgaaggaat tgctcatact atcccaagca caaaaccctc agtcgtttga ccgagggttc
     3841 ctttttatta ttcaagaact tgattagctc aatgcatcca aggcgtcatc cattgaaaga
     3901 acttcgtgga agacacgttg tgtcaattca gttttttgtt ctggagtgag gtatttagtg
     3961 tttacacagt atccagagat acgtacgata acgtcttcgc ctgacatgat tttttcgtaa
     4021 acatcgttca agtccataac gttcaagtta acgtgttgtc caccgttttc gaagtaacca
     4081 tcaaggattg ttaccaagtt atcaacttgt tcatcacgag tcttaccaag agcgcgaggt
     4141 gatacttgtg tagtcaatga gataccgtca gctgcataac taaagtcaag gctagaaagt
     4201 gagttcaagt tttgcaacca accaccttta gctttgttag atgggttagc acctggtgag
     4261 aagaattcaa gtttagacaa gttcacagaa ccatcttcgt tgaggtatac acctttgtga
     4321 actggtgagt taccagtttg tttagagtaa gcaacgttag atgtgattgt caaaagtgat
     4381 actgtagctt ctgcgtcttt gtatagtttg tggctacgta gacgagttgt gtaagcttcg
     4441 atcaaccatt ctgccaattc gtttgaacgt gggtcatctt caccccagcg tgggtagtca
     4501 ccgattgttt cgtaatcgta gatgtagcca tcttcgtcac ggattggttt aactgtagcg
     4561 tatttgatag ctgacaatgt atcaacagtg ttagcaaatc cacagatacc gaatcccatg
     4621 ttggcacgtt gtttagttgg caagaaggcc atttgaacag cttcgtagtt gtacctatca
     4681 gtcatgtagt ggatgatgtt caaggcatct acgtaagtgt cagtcaacca gtcaagagat
     4741 ttttcaaagt tcgctttaac tgattcaaat tcaagaactt cgtcacggat tggttcgata
     4801 tcaaatactt tgtagtcttt gtgaacatcg tcgtaaccac cattcaaacc agtaagaagg
     4861 gctttaagaa cgtttacacg agcaccgaag tactggatgt tgtggcgttg ttcttcattt
     4921 tctggatcaa gtggagacac acagcatgag atacagctca tttcaccata tccgtcttta
     4981 gccattgttg ttacaccttc gtattggata gaagagtgtt tgtggctcat gtgcatacag
     5041 tagcgacgga agttgtatgg caatttgtca gtccaaagaa ctgtcaagtt tggttctggt
     5101 gagttaccga tgttgtcaag agtgttcaag aaacggtagt ccatcttagt aacacggtga
     5161 cgaccgtcgt tacccatacc agccatagaa gttgtgataa aggttgggtc acctgagtac
     5221 aattggtcat aagcttttgt acgagcaaat ttaactgtac gaagtttcat aacgaaatca
     5281 tcaacgaatt cttggatttc tgattcagta aatgtaccac gagcaaggtc acgttctgca
     5341 aagatgtcca atacgattgg tacacgacct agagatgtag cagcaccgtt aatcacacgg
     5401 cagacagcca tgaaagcaat gttaacccat tggattgctt ctttcacgtt catcgctggt
     5461 ttgcgaacat caaccccgta aaggtcaccc aggcgaacaa cttgttgcaa tgcttggtat
     5521 tgaaggttta cttcttcacg aagacggatt gtttcttcat cgatttcttt gattgcattc
     5581 cagtcattta ctttttcttg catcaagtag tctgcaccgt aaagagcaag acgtgcgtaa
     5641 acaccgatga tacgtccgcg tgagtatgca tctggaagac cagttacagt gtgtgcgtga
     5701 cgagcgcgac gaatatttga agtgtaggca cggaaaatac cgtcgttaac tgttgttaca
     5761 tatttagtga agatttcgtg aacagctggg tctggttcgt atccattttc tttcaaagta
     5821 gtttcagcca tacggatacc accttttggc atgaagttca atttgaagag ttcatcgttt
     5881 tggataccga agataacttc attttctttg tcgataaatc cagcagggat atcagcgata
     5941 gatgttggac gagtgtccat tgggaaacga gtttcttcgt agtgtgcttt agtttcttct
     6001 acaattttct tgatgtgaag tgaacgctct gttggtcctg caaggaagct ttcgtctcca
     6061 tcataaggtg tgtagttagc ttgtacaaat cgtgatacac ttgctttttc tttccaatct
     6121 acgcctttga agccttccca agctttgtca aaaatatctt gtgcttcaac aactgtctta
     6181 acaaccatat taatgtcctc ttttttctag taacagtcat ctgttacatt cataagacaa
     6241 gtataccata tagtaaccga tttcaacaag tgaaaattcc ctatttttac actttctttt
     6301 ctaaaacagt ctatatttta tttcaaactg tattatattt ttgaaaaaat aaagtccttt
     6361 tttctttttt tcagaaaaaa gggtataata aaagaaaata agcagtaaca ctcaatggaa
     6421 atcgaaaagc aaactaggaa gctagccgca gattgctcaa aacactgttt tgaggttgca
     6481 gatagagctg acgtggtttg aagagatttt cgaagagtat aaaaaggtgc taggcatgtt
     6541 gatttttcct ttgttaaatg atttgtcaag aaaaatcatc catattgaca tggatgcctt
     6601 ttttgctgca gtggaaatca gggataatcc taaactcaga ggaaaacctg tcattattgg
     6661 aagcgaccct cggcaaacag gtggacgggg agtcgtttct acctgtagtt atgaggcaag
     6721 agcttttggt gtccattctg ccatgagttc caaggaagct tatgaacgtt gtccccaggc
     6781 tgtctttatc tcagggaatt atgagaaata caagtctgtg ggactccaga ttcgagctat
     6841 ttttaagcgc tatacagatt tgattgaacc catgagcatt gacgaagcct atttggatgt
     6901 gacagaaaat aaactcggta tcaagtcagc ggtcaaaatt gctcgcctca ttcaaaaaga
     6961 tatctggcaa gaactccatc taactgcttc cgcaggcgtt tcttacaaca aattcttagc
     7021 taaaatggcg agtgattatc aaaaaccaca tggtttgaca gtgattctac ctgaacaggc
     7081 tgaggatttt ctcaaacaaa tggatatttc caaatttcat ggagtaggaa aaaagacagt
     7141 agaacgtctt catcaaatgg gcgtttttac tggtgctgat ttacttgaag ttcctgaggt
     7201 aaccctaata gaccgttttg gtagactagg ctatgatctg tatcgaaagg ctcgtggcat
     7261 tcacaactct ccagtcaaat ccaatcgcat ccgtaaatca atcggcaagg agaaaaccta
     7321 cgggaagatt ctccttgctg aggaagatat caaaaaagag ctgactcttc tatcagaaaa
     7381 agtcgctctc aatctacatc aacaagaaaa agctggaaaa attgtcattt tgaaaatccg
     7441 ctacgaggac ttttcaactc ttaccaaacg aaaaagtctt gctcaaaaaa cacaagatgc
     7501 tagtcagata agccaaatag ccctgcaact ctatgaagaa ttaagcaaga aagaaagagg
     7561 tgtccgccta ttggggatta ccatgactgg attttaaagc tcaatgaaaa tcaaagagca
     7621 aactaggagg ctagccgcag gctgctcaaa acactgtttt gaggttgcag ataaagctga
     7681 cgcggtttga agagattttc gaagagtata aaaccttgaa gagttgcccc ttcaaggttt
     7741 ttcttataca aataaacgga caaaactgta aagtagcaaa acactaccaa gcacgatacg
     7801 gtatttacca aaaagggtga agtcgtgttt tttcacatag ctggtcaaga agcgaatagc
     7861 caccatgctg accgcaaaag ctactcccat cgcgaccaag agcaaaaaca attgcccaaa
     7921 gctcaagagt tctccggctt tcacaaattt gaaaatcttt aaggcactag ctccaaacat
     7981 aacaggaatc ccaagataga aggtaaattc tgtcacaact gaacgactgg ttccatttaa
     8041 caaaccaccg acaatcgttg cacctgaacg gctagtccct ggtaaaagag caagaacttg
     8101 gaagagtccg atatagaaag cggtcgtata aggaagcttg tccaactctg ttacacttgg
     8161 ctcgatagca cgcgctttat tgcgcttttc caaatagatg aaggcaaccc cgtagataat
     8221 caacatgaga gcaactgaaa ccatgttatg gaagtgggta tcaaaccaat catcaaattt
     8281 aaagacacca agtaaaggta aagtagcaat caagaccttc aaccatagtc tccaagtctt
     8341 acgaacttcc tgtttgtcct tagtcggttt aaaaggattg agcttgttaa aataaatcac
     8401 cataactgct aaaatagcac caagctgaat cacgacatta aacatggaca taaaggcttc
     8461 attttgattt tggtattgga tgaattcctc tgctaaaatc aagtgacctg tactggaaat
     8521 cggcaaccat tccgtaattc cttcaacaat cccgaagaag atagatttta aaatttcaat
     8581 aagatacata gattactccc tatattataa ttagcgcagt tagctactgc caaagcccaa
     8641 gtggtatact tggaataagc cactgtggat tagttcattt cctccaatcg cttgacgatt
     8701 tccgaaaggc tctaaccaca gcttttgttt caattggtaa tgagtttgat aacgcataga
     8761 cgtttgatct cgtctaaggt aacaaggcaa aaaattcgtg gataaccaag tagacttgaa
     8821 atactatatc tggaggtact cccatgcttt atgtgggcat tgatatcgct aaaaataaac
     8881 acgatgttac agccttgaat gttccaggaa aaactgttct taaaccactc actttttcaa
     8941 ataataaagc tggttttgaa ctcttagatc tgtctcttcg acagctcaac caagactgtc
     9001 tcatcgctct tgaaaatacc ggacattatg cctttaatct actgaacttc ctgcatgaac
     9061 aaggatataa agtttacacc tacactcctt tgctcatcaa ggaatttgcc aaatcattat
     9121 cacttcgcaa gactaaaacg aataagaaag acgctcatgg catcgctctt aaacttcttt
     9181 ctgaccccaa tcgtgaacaa tttcaacacg ataatcggca agtagaacta aaaatactgg
     9241 ctagacatat tcatcgtctc aagaaaaaac agtctgattg gaaagtacaa tacactcgtt
     9301 gtcttgatat catctttcct gagttggata aaatcgttga aaagcattca gaatatacct
     9361 accaactctt gacatgctac cctaatcctc agaaaaggct tgaggcagga tttgataagc
     9421 tgatagaaat taagcgattg accgcttcta aaattcagga tatcctctca gttgcacctc
     9481 gttctatcgg aacaacatct cctgctcgtg aattcgaaat catcaaacat tacaagaggc
     9541 tcattgacaa ggcggaaaca tgtgtcaatg acttgatggc tgagttcaac tcggtcatca
     9601 cgacggtcac tgggattggg aatcgtttag aggcggtcat tttagccgag attcgaaata
     9661 ttcatgcctt tgataatcct gctcaattac aagctttcgc tggactggat tcttctattt
     9721 atcagtcagg tcagattgat ttagctggaa gaatgatcaa acggggttcc cctcatctgc
     9781 ggtgggcact catacaagct gccaaagcat gccctcgctt ttcacctgct tttaaggcct
     9841 atcttaagac taagttagaa taaggaaaac attacaatgt agccatcatc caccttgcaa
     9901 aaaaacttat ccgaaccctg ttttatatcc taaaaaagag ctgccatttg acgaacaaaa
     9961 agtgatgtaa tttctgaaat taacacagga ttacctttga aaaaatggac tttttcaagg
    10021 gctttttgcc gtgctctaaa atcatcgcca aatcatcaaa ttgaaataag aaatagttta
    10081 gataaaacta ttgacttttc ttatagtttg tcttttttct atcttccatt atatcatact
    10141 ttttcagtct atggtagctc tctttaaaag gcaccgatac tgccgccacc tccgcctcca
    10201 gagaagccac caccagaact tccacttcca gaagatacag agtaggtgct tgctgtattt
    10261 gcgacactag cataatggct catttgcgcg cttgaatgat aaaacagact gtgccagcca
    10321 taagctacat agagattgat atctggattt tccacttgaa tctgatgaac cttcatcaaa
    10381 tgactaacct tgtccgcata gccaaataag gtcgcataga ccaagaggcg attccagacc
    10441 acaatacttt ccagttcagc ctgatccaat cgtgcaatct cacgcaacat attttcaaaa
    10501 ctggtccaga gatagtagac ctcagctccc gcttcattta gaacaccatc acgattatct
    10561 agtcgaagct tccaataata gaaaacagac aaaactaacc ctagaaaacc aagtattggc
    10621 aaagggaggt aaagatagcc atgaacgtct aaactgtaca agaacaaacc aaatccgata
    10681 aataggggca ggatagtcaa ggcacccata cccacttgca aggccttttc cccaccagtt
    10741 aaaggacgat aataatctgg gagcccccag aaggaaactc gttttctcac tccttcttgc
    10801 atctggttca atacctcttc aaaagaagat ttgagttgaa gccctcttgc ttgaatccgt
    10861 ttttcatcag aaactttggc tctacgataa agactatcag ataccttgta atccgcaaac
    10921 aaattggaaa gagtttcttc ttttttacct gaaaaagcta gatttaggca gtctttctca
    10981 aagcttgaca aaccatcttc ttttactagc ctcaaaccaa ctgcatctcc ttctgaaatg
    11041 atagagacat tcccacggtc tatcacatct agcaaggtag cttgaataag ttgatcaaag
    11101 gtgaattttc cagctccctt gaccaaggga ctcacttcct ccaaggaggt cgagtagact
    11161 gcttctgata aaaccatagg ctctaattcc attggtggtt catagagacg atgatttttg
    11221 gcatatttga ctgaaggagt ggtctttctt ctataaataa aatagaagca gacactcaat
    11281 aacaaggaga tagaaaggat cgaagggagg acccaagtaa caagttgttt actctgatct
    11341 ttttctctaa caatcgagtc ttctatctta ttaaactctt ctaaacgatt ccctttcaat
    11401 ccctgatccc tagcgctagc aaaatcggtc cgaggccaat aggcatgcaa ctcaactcca
    11461 cgcttagccg gaagattgtc taaacggata gtataatcaa ggttactctt ttcaatcgtt
    11521 ccctctctaa aaagtttccc tgtatggaaa aagagttttt cagctccctt gtctcccctt
    11581 acatgaaatt caaacttttc aatagactct gaactatctg tcagaggttg ccaatttaat
    11641 tcagcgatat catcataaag gaaaagtaaa ttttttaagt tccagacgag gtcaacttca
    11701 actatgtcgc cctcctgacc tggattatag actctcacag tataaccatc cgcttcttct
    11761 gttacttcgc tagtcacatc tgctagttct gcaccgtttt tcgcggcctg aacctttgga
    11821 tgagggtcaa tgtcaaaccc gctaggcatc ttaccagcac gtccaagtcc cacgatttgt
    11881 cccttaaagt cctcctcaaa ctggtaaact atcttctgtc taaactctgc cgtattatct
    11941 gcatgaatat acaaatcccc ttgataagag tttatcttga aatcaatggc aaaaacagag
    12001 agtggaagaa ggcaaaacaa gcctaacacc agtaagaaaa aagttttttt catcaactaa
    12061 gccccctttt tatctttctt atcattatag cattttttcg taagtaaagg cttacttatg
    12121 ttgaaaaatt acgcattttt cgataaaata ggagacagtt attttttaat agatcagaat
    12181 aggagaaatc atgagaaaaa tatacttatc tattttcaca agtctcttgc tgatgctagg
    12241 acttgtcaat gttgctcaag ccgatgaata tttacgcatc gggatggaag cagcatatgc
    12301 tccctttaac tggacccagg atgatgatag caacggagct gtcaaaatcg atgggaccaa
    12361 tcagtatgcc aacggatacg atgttcaaat cgccaagaaa atcgctaagg acttaggtaa
    12421 aaaacctttg gttgttaaaa ccaagtggga aggtctagtc cctgccctta cttctggtaa
    12481 gattgacatg attatcgcag gtatgagtcc aactgcagaa cgcaaacaag aaattgcctt
    12541 ttcgagcagt tactacacta gcgaaccagt tttgcttgtc aaaaaagatt ctgcctacgc
    12601 aagtgctaaa tctttggatg actttaacgg tgcaaaaatc acttctcaac aaggggtcta
    12661 cctctacgac ttgattgcac aaatcccagg tgctaaaaaa gaaacagcca tgggagactt
    12721 cgctcaaatg cgacaagctc ttgaggctgg tgtcattgat gcttatgttt ctgaacgtcc
    12781 agaagcactg actgctgaag ctgcgaactc taagttcaag atgattcaag tagaacctgg
    12841 tttcaaaact ggggaagaag atacagctat cgctatcggg cttcgtaaaa atgacaatcg
    12901 tattagccaa atcaatgcca gcattgaaac catttcaaaa gatgaccaag ttgccttgat
    12961 ggatcgtatg atcaaggaac aacctgccga agctacaaca actgaagaga ctagcagtag
    13021 tttctttagc caagtcgcta aaattctttc tgaaaactgg caacaactct tgcgtggtgc
    13081 tggtatcact cttttaatct ctatcgtcgg aaccatcata ggtctcatta ttggacttgc
    13141 cattggtgtc ttccgtactg ctcctctctc tgaaaacaaa gccatttatg gccttcaaaa
    13201 actagtcggc tgggttctca atgtctacat tgaaattttc cgtggtacgc caatgattgt
    13261 tcaatcgatg gttatctact atggaactgc ccaagctttc ggtatcaacc ttgaccgtac
    13321 actagctgct atcttcatcg tttcaatcaa taccggtgcc tacatgactg aaattgtccg
    13381 tggtggtatc ctggcagttg acaagggaca atttgaagct gcgactgctc ttggtatgac
    13441 tcataaccaa accatgtgta agattgtcct acctcaggtt gtccgcaata tcctaccagc
    13501 aactggtaat gaatttgtca tcaatatcaa agatacatct gtattgaacg ttatctctgt
    13561 tgtcgaactt tatttctcag gaaataccgt ggcaacacaa acctatcaat acttccagac
    13621 atttacaatc atcgccgtga tttactttgt cctcaccttc accgtaacac gtatcctacg
    13681 ctttatcgag cgcagaatgg acatggatac ctacactaca ggtgctaacc aaatgcaaac
    13741 ggaggatttg aaataatgac acaagcaatc cttgaaatta aacacctcaa aaaatcctat
    13801 ggacaaaacg aagtgctaaa agacatttct ctcactgtcc acaagggaga agttatttct
    13861 atcatcggaa gctctggaag tgggaaatca accttcctac gctccattaa cctacttgaa
    13921 acgccaactg atggacaaat cctttatcat ggacaaaacg tcctcgaaaa aggctatgac
    13981 ctcacgcaat accgtgaaaa gttagggatg gttttccaat cctttaacct ctttgaaaat
    14041 ctcaacgttc ttgaaaacac aatcgtcgct cagacaactg tccttaaacg cgaacgcaca
    14101 gaagctgaag aaattgccaa agaaaacctg gaaaaggtcg gcatgggaga acgctactgg
    14161 caagcgagac ccaaacaact ctcaggtggt caaaaacaac gtgtggccat cgctcgtgcc
    14221 ctttcaatga atcctgacgc cattctcttt gatgaaccaa catcagctct cgatccagaa
    14281 atggttggag aggtcctcaa aatcatgcaa gatctggctc aggaaggctt gaccatgatt
    14341 gtcgtaaccc atgaaatgga atttgcccgt gatgtctctc accgtgttat ctttatggat
    14401 aagggtgtga ttgctgaaga aggtaaacca gaagacctct tcactaatcc taaagaagac
    14461 cgtacaaaag aatttcttca acgttatctc atactcaatg aaaatcaaag agcaaactag
    14521 gcagctagcc gcaggttgct caaaacactg ttttgaggtt gcagatagag ctgacgtggt
    14581 ttgaagagat tttcgaagag tatcaaataa aaagaaaagg ctgcatcaac cgtgcagtct
    14641 ttttgctgtc ctcaaaatga aaaggcagat tctctatctc tactacttga aggtcaagaa
    14701 tccaccgtta tccaaagatt aatcttcaaa tttttcatga tttttttcat agaaatcaat
    14761 taagcctagg gctgtttcaa atgaaatatt ttttactttt gcacgaccct gcgccagagc
    14821 aatgatagac atttcacgcg cattcgtttc tttagagata cggtagcctg tgattttctt
    14881 atcacgaacc cagccaacaa ctgattctac tttttcaaag tttgacttag ccatgttttt
    14941 ctcctatttt cttctttata atatttaatt gtatacgttt ttactacttt tgtcaaaaaa
    15001 aaaaacatat attcaacgaa aataattagt tcagaatttt cttacttcct ttttaaatcc
    15061 gataatatat aggttttgct agcctctaca ccataaatat ttgctaataa aaatactgta
    15121 ttattaccct cttaaggtgc aaaattattc aagttcttaa aaaatgcttc tctatttccg
    15181 taagatagct tatttcttcg atttaagaac tgaagatgat agttctaacc tttagaaatc
    15241 caagccttct ctagctcaaa aactcctatc tttcttcctc aataaatcat ctgagagata
    15301 ggtattcctt atatccttca aattcatcac tcctttggat attgaggtgc tagcctagaa
    15361 gcagacaccc gattatctaa accatcctta atagagatga caagacagat aagctcagtt
    15421 aattacttat atatcttttt aatatggtat atttgtcaac aaaaagaaat caaatcatac
    15481 cttatactca atgaaaatca aagagcaaac taggaagcta gccgcaaatt gctcaaaaca
    15541 ctgttttgag gtttcagata gagctaacgt ggtttgaaga gattttcgaa gagtattaaa
    15601 gacagtatga ctatgcttgt caatagatag gaaatcaaaa tgaaggatgg aaatctgagc
    15661 caaacatcat aagtgctata atgaacagaa gtaagaattg cacgataagt tttctaaaac
    15721 cataggaatc gtcccctttc ttcatcttca ttatagcaca tatacatcag ttgtacaaat
    15781 aatatgatat ttttttatta gtcctcagac aagcatatta taaagcgttt cattaccatt
    15841 taagttaata taagctggat caaaaccttc cattctacgg atcaaacctg cataatcatg
    15901 cttatctgcc aaagcgatcc caatcaatac tgggcctgtt cccttgctag ctcgtttgat
    15961 atactcaaaa cgtgtgatat catcatttgg ccccaggata tcatttacaa actcacgcaa
    16021 agctcctgga cgctgtggga aattgaccac aaagtaatgt ttgataccat cataaatcaa
    16081 ggcacgctct tccatttctg gcatacggtt gatatcatta tttcctccag aaatgataca
    16141 acaaatggtt ttccccttaa tatattcagc taaaacctct aaagaggcga tactagccgc
    16201 tccagcaggt tctgcgacta tcccttgctt agagtaaagg tcaatcaagg tttcagaaat
    16261 caatccctca tcgacaccta ccaaagtttg aatatgttga cgagttgctt cataggtcaa
    16321 ctgacctacc ttttgcacag caatcccatc cgcaaattta tcaatttcct tgagtttgac
    16381 tggacctcca gcctcaaagg cagctttcat ggaacgcgct ccattcgcct ctactccgat
    16441 aacctcaatc tctggacttg tttccttgat ataggtagaa accccggcaa tgagaccgcc
    16501 accaccaaca ggaaccaaga cagcatcaaa atcaatcgat tcttttcgag cttcttctaa
    16561 aatctcataa gcaactgttc cttgacctgc ttgaacatga gcatcatcaa aaggatcaat
    16621 aaaggtacga ttttcagaga ctgtaaattc ttgagctgct ttggctgagg catcaaaggt
    16681 atctccaact agtttaatag ttacaaaatc cccaccaaaa aagcgaacct gaccaatctt
    16741 ttgttgtggc gtagtaatag gcataaagat agtagcagga attttcattt cattacaagt
    16801 ataggctact ccctgcgcat gatttcccgc agaagcgcag actaccccac gttcacgttc
    16861 ttccttgctg agctgggaaa tggcataata ggcaccacga attttaaagg agcgaacacg
    16921 ctgggcattt tcttttttca aataaatctt agcaccatac ttctccgata aataatgatc
    16981 gtaatccagt ggagtattca caaccacacc gttcaagacc ttgtgagcct tgattatatc
    17041 ttttgaactt aacatataaa acctcttttt ctataaaaaa cagtcactaa tgactgtttt
    17101 ttagttattc atctccgaaa acttcagtaa cactttcatg gtatttatga gccatacgaa
    17161 tcgaaaactc tttaggaagt tcataacgat ttgtggaaat ccaatcatat aaccattcta
    17221 ccaaactttc ttcactatca ttacgatgga agataaaata gtttaaaatt tctttatatt
    17281 ctacatcatt caaatccaac gtgtctacaa attgactacg aggaacaaaa ttagaatcta
    17341 attttcttag ttgatctgtc aattctccca attgtaaatc caactgaaaa aatagttttt
    17401 gcagttgcct atcagtttca tcacatcctg tcttgataga aaacaaattg gtaatattca
    17461 tatgatttca acccctaaat aagtacatct aatatcccac gaatagctga agctaaagtt
    17521 ttcgcagtcc agtcatttaa acccgattct ttcaatccag atgcaataat ttgctctatt
    17581 tgatataaac cgccatctat cgtctcattt attctgcgaa gaggaccttc aatataggat
    17641 aaagcttctc cgaatctaac agctgattta ggtcctaatg atttaccaac tatatttgtt
    17701 aatgtttttt atttctcaaa atccatttcg ctatataacg agcagatttg gtcgcaccag
    17761 ctctctcaaa cggagaatga atttcaagac cttcttctct agctatttgt gccaatttga
    17821 agaattgttc aaaggtcata tgcaacctac catcttcaaa attagcatca tcataaatgt
    17881 taattacagc attttcatca tacgaccaat ctgctttatt ttggtctgct agcactatta
    17941 ccgacggtgt aattacatta tacaactaga accaataata acgatgcaat ttttctcata
    18001 atctttttca taaaatcatc tccagcgcta tatatttcta attagttata gattttgaat
    18061 gcatcatcgt cgtttttacc aacaaatggc attgctttac gcaattctgc accaactttt
    18121 tcaatttcaa ggttagctgc ttgttcacgg taagcagtca attttggacg tccagcttta
    18181 tagtcattta caaagtcatt tgcaaattta ccattttgga tgtctgccaa gacagccttc
    18241 atattttctt taacttgttc agtgattaca cgtggacctg atacatagtc accgtattca
    18301 gcagtgtttg aaatagattg acgcattttc ttgaatccac cttcgtagat caagtcaacg
    18361 atcaatttca tttcgtgaag aacttcaaag taagccaatt ctggagcgta acctgcttct
    18421 gtcaagactt cgaaacctgc ttcgataagg gcagtcaaac caccacaaag tacagcttgt
    18481 tcaccaaaca aatcttcttc agtttcttct ttgtaagttg tttcaagaag acctacacga
    18541 gccgctccaa cacctttaca ccagtccata gcaatgtttt tagcatttcc tgttgcatct
    18601 tggtatactg cataaagagc tggaacacca aatccttctt cgtaagtacg acgtaccaag
    18661 tgtcccggtc ctttaggagc acacatgaag acatctacat ccgcaggaac tttgataaat
    18721 tcaaagtgga tgttgaaacc atgggcaaat ccaactgcgt ttccagcttc caagtttgga
    18781 gcgatttctg cttcgtacaa ttcttgttga atttcgtctg gcgccaagat catgataaca
    18841 tcagccaact tagtagcttc tactactgtg taagtatcaa atccatcttc ttttgcttta
    18901 tcaaaagatt tacctggacg tacaccgata ataacgtcac gacctgaatc acgcaagttt
    18961 tgagcatgcg catgtccttg tgaaccataa ccgataacgg cgattttttt accgtcaagt
    19021 gctgctactt taacatcttt ttcatattcc atttgaactg tcatagcttt tctctctttt
    19081 ctattattta ttgcctttta ggctggttta ataaatttaa gttggatttt taatcgcggg
    19141 taaatccagt tgcacccgtt cgagcaatat tgcgaatacc gtatgggcga atgactcgca
    19201 atagggcttc gctcttttct gcatttcccg tcatctgaat ggtaatcgag cttggcgcta
    19261 cgtctaccac tgttgcacgg aaaggttgaa taatcgctaa aatctcagct ctcttctcag
    19321 ctggcgctga catcttaacc aaaatcacct cgcgctccaa atgaggcttg tctgtaatat
    19381 ctcgaatgcg aatcacatca atctgacgat tgagctgttt gatgatttgc tccacttcat
    19441 catgagaagc aacatcaata ataatagtga tacgcgatac attcggatct tctgttgctc
    19501 caacagagat gctttcaata ttaacctgac gacgagatag gacacctgta aagcgattga
    19561 ggactcctga acgattttgt agttttgctg ttaacattct acgcatggaa ctgcaccccc
    19621 aacatctcat gattactctt accagccggt accattggta acacctgttc cttacgagaa
    19681 atatctacct caattagcat aggaacatcc tcagtgatga cttcaaggtc ttgagccaag
    19741 gtctcaggat tgtcaaactt atagttttta ataccataag cctgcgccat caattggaaa
    19801 tcaggaaggg tatcaaagac cgactctgat gttctgcctt catagaagga ttcctgccac
    19861 tggcgaacca ttccaagtga atgattgttc agcataacca ccttgattgg caccttgtaa
    19921 atattcaaaa tagccaactc ctggttggtc atttggaaac caccatcccc aacaaacaag
    19981 actacttcct tatctgggtt agcaatttta gcaccgattg ctgctggaat tccaaagccc
    20041 attgttccca aaccacctga agtcactaac tgacgctcat tttggtaggg ataatactga
    20101 gctgtccaca tttggtgttg accaacgtct gttaccacaa tggcatctcc attcgtcaat
    20161 tcaccaattc gttcaataac tgcttgcggt tgaaccacac gctctttctt gtcataagaa
    20221 cgaacacgat tcttgtcttt agtgactttc tcaatccact tttcagtatt gttgtgaact
    20281 gttggttctg ctagcaacat ttgcaaggcc ttcttagcat ctccaactac aggaatgtct
    20341 gcactgataa tcttgccaat ctcagctggg tcaatatcaa tgtgggcaac cttagcattc
    20401 ttagcgaaag tcttaggatt ccccgtcaaa cggtcatcga aacgagaacc aatactaatc
    20461 ataaagtccg cttccgtcat ggcaatattt gctgcgaatg acccgtgcat gcctcccatt
    20521 ccaagaaaga gtgggtgact cgttgcaatc gttccttgtc ccaaaagact ggttaccact
    20581 ggaatttgat agcgttctgc aaattcattt agttccgtag cagcctcagc ataactaatt
    20641 ccaccaccag ctaacaagac tggcttttta gccttggaca attgcttcaa gattttcttg
    20701 atttgcatat cattcggctc aagagtcggc tgataacttg gtaaattcac ttctggtgaa
    20761 taaatgaagt ctgtttctaa agcagatatg tcttttggta ggtcaattac aactggccct
    20821 ggacggcctg tagttgcgat atggacagct tccgtaatga tacgcggaat atcagctgtc
    20881 tcacgaactt ggtaattgta cttagtgatt ggcatggtaa ttcctacgat gtctgcctcc
    20941 tgaaaggcat ccttcccaat ccctgctcgc gccacctgac ctgtaaagac caaaagggga
    21001 acgctatcgc tcatagcatc cgcaatccct gtaatggcat ttgttgctcc tggtccacta
    21061 gtgacgacgg caacacccaa ctttccagtt gatttggcat aaccttcagc ttcatgcaaa
    21121 caaccttgct catggcgccc tagaatgtgg cgaatgcctt taaaattata tatcgcatca
    21181 taaaaaggca aaaccgcacc accaggataa ccaaagatgg tatcaactcc taaatcacga
    21241 agtgtttcca aaactaggtc cgaccccgtc ttaggagatt ctaaactgat tttctccatt
    21301 gttccccttt ctttcctctt aaaaataact tgttactatc ataccatttt ttcaaaattt
    21361 ttcaagataa aagaagaaat tttctgaatt ttctatttta acgtttattt atgaatgtta
    21421 tttttgtttt tattaaaaag ataccgattt catttactaa aaaagaaaaa agaactgatt
    21481 tctcagtcct tcattaatct tattccacac taaataggta tgggtaaaca ggttgttgac
    21541 cttggtgaat ctcgacttca acgtcttcga attcttctac gatttcttga gcgatttcat
    21601 tggcaagttc ttcgcttccg tcttcaccga catagaaggt tacgatttca ctatcttcat
    21661 ccaacatatg tttcaaggtt tcagtcaatg tttggtgcat atcagggttt gacacaagaa
    21721 tttttccatc caccatacct agattatcgt tttcatggat ttctaagcca tcgatcgttg
    21781 tatcacgcac ggctgttgtg acgcttccgc taacgacatc gctaagagca gctgtcatac
    21841 gctcttggtt ttcttcaatg gacttgcttg gatcaaaggc aagaagactt gtcatacctt
    21901 gaggaagagt gcgagcctct accactactg ctggttgctc caaaacttct gccgcagatt
    21961 gagctgccat gaagatgttc ttgttgtttg gcaagaagat gatgttacgg gcattgacct
    22021 gttcaacagc cttgataaag tcttctgttg aagggttcat ggtttgaccg ccttcgataa
    22081 cataatccac gccttgagaa cagaagatat ctgctagacc tttaccagcc accacagcaa
    22141 tcaaagcata ctctttttct tcagccgact tgataacttg agtagcttct ttctcaacct
    22201 gtgcttcgtg ttggttacgc atattgtcaa cttttacctt gaccaagcta ccatatttga
    22261 gaccttcttg cataacaagt cctggatctt ctgtatgaac atggactttg acaatttcat
    22321 catcgttaac aacgaggaga gaatccccaa gctcatccaa gtagttacgg aattcatcgt
    22381 agtcaaaatc tttagcatag gttggacctt gcttaagagc taccatgatt tcagtacagt
    22441 aaccaaacgt gatgtcctca gtcgctacgt gaccagctac agacttatga tgctctacat
    22501 tgatcatctc actcatgttg gcaggagtcg ctacaaagtc ctcagatgca atatattcgc
    22561 cagtaagggc tgaaaggaaa ccttcgtaga tgaagaccaa tccttgacca cctgagtcca
    22621 caacgccaac ttctttcaat actggaagca tgtctggtgt tttagctaga gctgttttag
    22681 caccttccaa ggctgcgcgc atgacttcaa cagtgtcatc tgtttgctca gcttttttct
    22741 tagcaccgat agcagctcca cgagaaactg tcaaaatcgt tccttcaaca ggtttcatca
    22801 ctgccttata ggcaacttcc acacctgatt ggaaggccag agccaagtct tgacctgtta
    22861 actcgtcttt atccttgata gcttgggaaa atccacggaa aagctgagac gtaatcactc
    22921 ctgagttccc acgcgcaccc atcaaaagcc ctttggcaag aatgctcgct acttctccaa
    22981 ctgtagaagc tggcttgtct gcaacttctt tagcaccatt ttcaatggtc attcccatat
    23041 ttgtcccagt atctccatct ggaactggaa agacgtttaa tgaattgaca tattcagctt
    23101 gcttattcaa gcgagttgat gcagcctgca ccatttcttg aaataagcta gtagtaattt
    23161 ttgacacggt tattctccta caactttgat attttgaatg tagacattta cagtctgagc
    23221 agtaattcca agctggtttt ccaagctaaa ggcaacacgc tcttgaatgt tttttgacac
    23281 ttcactaatc tttgttccgt agcttaacac ggtatataca tcaactgcaa tactgccatc
    23341 ttcggctgcc tttacgacga cacctttaga ataattttcc ttacctagca gggcttggaa
    23401 attatctttg agggcatttt tactagccat accgaccaca ccaaaaatct cagttgctgc
    23461 tccacctacg acggttgcaa tcacttcatc tgttagttcg atttgaccat cttttgtatt
    23521 aatttttaca gtcatccttt ttacctcaac tagttgatac tctattttat catatttcag
    23581 cccaagtgta aaagcagaat gatgtatcag cggatattta ctctattttt caaacgatgt
    23641 tatacccaca ataaaagaaa aaagacccta aggtctcctt tgcttttatt attaaacgcg
    23701 ttcaacttta cctgatttca aagcacgagc tgaagcccaa acttttttag gtttaccatc
    23761 gataagaaca gtaacttttt gaaggtttgg ttttacggca cgttttgttt ggttcatcgc
    23821 gtgtgaacgg ttgtttcctg atacagtctt acgacctgta aagtaacata ctttagccat
    23881 tgtgttttcc tcctattaga tctaatatag cggatgtgct agcaccacat accgtactat
    23941 gttatcacac tttcttgttt tttgcaaggg aattggaaga ttttttattt gtgtcttaaa
    24001 tcaggtcttg cgtgacattt tctgctctcc acatgccatc gttgattaac agaacaccag
    24061 aattaaaatt atgtgtataa aaatcatctc taactgcagc taagggtata gccgtcaagt
    24121 ccaaatccca cagctcatct atcgattttc ttacaacaat atctgaatcc aaatacagta
    24181 cacgagactc gcttacatac tttggaataa aatacctaaa aaagccgcat atgaaagtcc
    24241 ctcaaagggg agacgataac ctttcagaat actactgtca atctaaacat tcacaatctc
    24301 actattcaaa gtctctagtc ttttttccat taattggaac cattctcgcg gaaggtcatc
    24361 attaaaaaca taaaacttaa gattataatg atgaacacaa agagatttta ttgttgtttc
    24421 aactttatcc atataagcat tatctgcacc taagacaatc gcttttttct cttctttcac
    24481 tttttatctc atttcttttt attcccatca tatgtttcta cgtaaccatt attttcgcct
    24541 attcgttcgt aaaaccatac cagtggagat tttagatgaa gtcccattac ggtttacaat
    24601 ttttacatta cgacacagag ttttacaaat cgatttcatt tgccaaacgt agttagtaag
    24661 gcagttagct aggctaccta ctttctgcta cgacggaaaa atccacaaat caataccatt
    24721 cgtggatttt tcctagtgaa gcgtttaggt aagccgccat agcggttacc gattattaga
    24781 ttacgacacg gagtttggca aatcgattct atttgccaaa cgtagttagt gaggcagtta
    24841 gctagttcgc caaatagcga ctagcgtcca acaatttgga actttagttc caattgttgg
    24901 tactgagtca catcttctcc tctaactcta cgtctggata cttgtccgca aaccagcgga
    24961 gggcaaagtc attttcaaag agaaagactg gttggtcaaa acggtctttg gctaagatat
    25021 tgcgacttga cgacatccgt tcatccaagt cctcaggctt gatccaacga acggtctttt
    25081 tacccattgg gctcatgacc acttccgcat tgtattcgcc ttccatacgg tgtttaaaga
    25141 cttcaaactg gagttgacca acagctccca gcatgtactc acctgtttgg taattcttat
    25201 aaagctgaac ggctccttct tgcaccaatt gctcaatccc cttgtggaag gatttttgct
    25261 tcataacatt cttagcagaa actttcatga aaatttcagg agtaaaggtt ggcaatggtt
    25321 caaattcaaa cttgtttttt ccaaccgtca aggtatcccc aacctgataa gtaccggtat
    25381 cgtaaacccc gataatatca cctgccacgg cattggtcac attctcacga ctctccgcca
    25441 taaactgggt aacattagat agtttagccc ccttaccagt acgagggaga ttgacactca
    25501 tgccgcgctc aaattcgcct gatacgatac ggacaaaggc aatacggtca cggtgacgag
    25561 gatccatgtt ggcttggatt ttaaagacaa agcctgagaa atccttgtca taaggatcca
    25621 caatttcacc atctgttttc ttgtgaccat gtggttctgg agcaaacttg aggaagattt
    25681 caaggaaggt ctgcacacca aagtttgtca gggctgaacc gaaaaagaca ggcgtcaatt
    25741 ctccagccag aatagcttcc tctgaaaact cattcccagc ttcatttaaa agctcaatgt
    25801 catccttgac ttgctcgtag aaaggattgc taccaaaaag tttgtctcca tcttctaggc
    25861 tagcaaaacg ctcatcccct ttataaagtt ctaaacgttg gttatagagg tcatacaagc
    25921 cctcaaaggc tttccccatc ccgataggcc agttcatagg gtagctagca atgcccaaga
    25981 tttcttccaa ttcttgcaag agttccaaag gctcacgacc gtcacggtcc agcttgttca
    26041 taaaggtaaa gactggaatg ccacgatgtt tcacaacctc aaacaatttc ttggtttgag
    26101 cctcgatccc cttggcagag tccacgacca tgaccgcagc atccaccgcc atcaaggtac
    26161 gataggtatc ttctgagaag tcctcgtgcc ctggcgtgtc taagatattc acgcgcttgc
    26221 cgtcgtagtc aaattgcata acagatgaag taacagaaat cccacgttgc ttctcgatat
    26281 ccatccagtc agatttagca aaagtccctg ttttcttccc ttttaccgta ccagcctcac
    26341 gaatctcacc cccaaagtag agtaactgct cagtgatggt tgttttcccc gcgtccgggt
    26401 gggagataat ggcaaaggta cgacgtttct taatttcttc ttgaatattc ataagttctc
    26461 tttctttgat tctctatttt tcttgtttca atagctgaga atgattttta cattggattt
    26521 taccattcct ttcaatactc cattatatcg gattttagca tttttttcaa tttctatttc
    26581 ttttcacttc cccctccctt atttatagga aaatatggta aaatagaaca gactaaaaat
    26641 catcatttca cgaaaggatg caagatgaaa attacgcaag aagaggtaac acacgttgcc
    26701 aatctttcaa aattaagatt ctctgaagaa gaaactgctg cctttgcgac caccttgtct
    26761 aagattgttg acatggttga attgctgggc gaagttgaca caactggtgt cgcacctact
    26821 acgactatgg ctgaccgcaa gactgtactc cgccctgatg tggccgaaga aggaatagac
    26881 cgtgatcgct tgtttaaaaa cgtacctgaa aaagacaact actatatcaa ggtgccagct
    26941 atcctagaca atggaggaga tgcctaatga cttttaacaa taaaactatt gaagagttgc
    27001 acaatctcct tgtctctaag gaaatttctg caacagaatt gacccaagca acacttgaaa
    27061 atatcaagtc tcgtgaggaa gccctcaatt catttgtcac catcgctgag gagcaagctc
    27121 ttgttcaagc taaagccatt gatgaagctg gaattgatgc tgacaatgtc ctttcaggaa
    27181 ttccacttgc tgttaaggat aacatctcta cagacggtat tctcacaact gctgcctcaa
    27241 aaatgctcta caactatgag ccaatctttg atgcgacagc tgttgccaat gcaaaaacca
    27301 agggcatgat tgtcgttgga aagaccaaca tggacgaatt tgctatgggt ggttcaggtg
    27361 aaacttcaca ctacggagca actaaaaacg cttgggacca cagcaaggtt cctggtgggt
    27421 catcaagtgg ttctgccgca gctgtagcct caggacaagt tcgcttgtca cttggttctg
    27481 atactggtgg ttccatccgc caacctgctg ccttcaacgg aatcgttggt ctcaaaccaa
    27541 cctacggaac agtttcacgt ttcggtctca ttgcctttgg cagctcatta gaccagattg
    27601 gaccttttgc tcctactgtt aaggaaaatg ccctcttgct caacgctatt gccagcgaag
    27661 atgctaaaga ctctacttct gctcatgtcc gcatcgccga ctttacttca aaaatcggcc
    27721 aagacatcaa gggtatgaaa atcgctttgc ctaaggaata cctcggtgaa ggaattaacc
    27781 cagaggttaa ggaaaccatt caaagtgccg ctaaacactt tgaaaaactt ggtgctattg
    27841 tcgaagaagt cagccttcct cactctaaat acggagttgc cgtatactac atcatcgctt
    27901 catcagaagc ttcatcaaac ttgcaacgct ttgacggtat ccgttacggc tatcgcgcag
    27961 aagatgcaac caaccttgat gaaatctatg taaacagccg aagccaaggc tttggtgaag
    28021 aggtaaaacg tcgtatcatg ctgggtactt tcagtctttc atcaggttac tatgatgcct
    28081 actacaaaaa ggctggtcaa gtccgtaccc tcatcattca agatttcgaa aaagtcttcg
    28141 cggattacga tttgattttg ggtccaactg ctccaagtgt tgcctatgac ttggattctc
    28201 tcaactatga cccagttgcc atgtacttag ccgacctatt gaccatacct gtaaacttgg
    28261 caggactgcc tggaatttcg attcctgctg gattctctca aggtctacct gtcggactcc
    28321 aattgattgg tcccaagtac tctgaggaaa ccatttacca agctgctgct gcttttgaag
    28381 caacaacaga ctaccacaaa caacaacccg tgatttttgg aggtgacaac taatgaactt
    28441 tgaaacagtc atcggacttg aagtccacgt agagctcaac accaattcaa aaatcttctc
    28501 acctacttct gcccactttg gaaatgacca aaatgccaac actaacgtga ttgactggtc
    28561 tttcccagga gttctaccag ttctcaataa aggggttgtt gatgccggta tcaaggctgc
    28621 tcttgccctc aacatggaca tccacaaaaa gatgcacttt gaccgcaaga actacttcta
    28681 tcctgataac cccaaagcct accaaatttc tcaatttgat gaaccaatcg gatataatgg
    28741 ctggattgaa gtcaaactag aagacggtac gaccaagaaa atcggtatcg aacgtgccca
    28801 cctagaggaa gacgctggta aaaacaccca tggtacagat ggctactctt atgttgacct
    28861 caaccgccaa ggggttccct tgattgagat tgtatctgag gcagatatgc gttctcctga
    28921 agaagcctat gcttatctga cagccctcaa ggaagttatc cagtacgctg gcatttctga
    28981 cgttaagatg gaggaaggtt cgatgcgtgt ggatgccaac atctcccttc gtccttatgg
    29041 tcaagagaaa ttcggtacca agactgaatt gaagaacctc aactccttct caaacgttcg
    29101 caaggggctt gaatacgaaa tccaacgtca agctgaaata cttcgctcag gtggtcaaat
    29161 tcgccaagaa acacgccgtt acgatgaagc taacaaaaca accatcctca tgcgtgtcaa
    29221 ggaaggggct gcagactacc gctacttccc agaaccagac ctacccctct ttgaaatttc
    29281 tgacgagtgg attgaggaaa tgcggactga gttgccagag tttccaaaag aacgtcgtgc
    29341 gcgttatgta tctgaccttg gtttatcaga ctacgatgct agtcagttga ctgctaataa
    29401 agtcacttct gatttctttg aaaaagctgt tgccctaggt ggtgatgcca aacaagtctc
    29461 taactggctc caaggggaaa tcgctcagtt cttgaatgct gaaggtaaaa cactggaaca
    29521 aatcgaattg acaccagaaa acttggttga aatgattgcc atcatcgaag acggtactat
    29581 ttcatctaag attgccaaga aagtctttgt ccacctagct aaaaatggcg gtggcgcgcg
    29641 tgaatacgtg gaaaaagcag gtatggttca aatttcagat ccagctatct tgatcccaat
    29701 catccaccaa gtctttgccg ataacgaagc tgctgttgcc gacttcaagt caggcaaacg
    29761 taacgccgac aaggccttca caggattcct tatgaaggca accaaaggcc aagccaaccc
    29821 acaagttgcc cttaaactac ttgcacagga attggcgaag ttgaaagaaa actagacaga
    29881 acaaaaccag ccctaaggtt ggttttttct tctctaccaa ctcccaataa ctattttggc
    29941 tttatttcca gagtatttta tggtaaaatg aagagtaata atatttatta aagaggtaaa
    30001 aacatgattg aagcaagtaa attaaaagct ggtatgacct ttgaaacagc tgacggcaaa
    30061 ttgattcgcg ttttggaagc tagtcaccac aaaccaggta aaggaaacac gatcatgcgt
    30121 atgaaattgc gtgatgtccg tactggttct acatttgaca caagctaccg tccagaggaa
    30181 aaatttgaac aagctattat cgagactgtc ccagctcaat acttgtacaa aatggatgac
    30241 acagcatact tcatgaatac agaaacttac gaccaatacg aaatccctgt agtcaatgtt
    30301 gaaaacgaat tgctttacat ccttgaaaac tctgatgtga aaatccaatt ctacggaact
    30361 gaagtgatcg gtgtcaccgt tcctactact gttgagttga cagttgctga aactcaacca
    30421 tctatcaaag gtgctactgt tacaggttct ggtaaaccag caacgatgga aactggactt
    30481 gtcgtaaacg ttccagactt catcgaagca ggacaaaaac tcgttatcaa cactgcagaa
    30541 ggaacttacg tttctcgtgc ctaatctcta gaaagaggtc attctatggg aattgaagaa
    30601 caacttggcg aaatcgttat cgccccacgt gtacttgaaa aaatcattgc tatcgctact
    30661 gcaaaggtag agggtgttca ctctttttca aacagatcag tgtctgatac cctttcaaaa
    30721 ctttcactcg gccgtggcat ttatcttaaa aacgtggacg aagaactcac agcagatatc
    30781 tatctctacc ttgagtacgg agtaaaagtt cctaaggtag cggttgctat ccagaaagct
    30841 gtcaaagatg ccgtccgtaa tatggctgat gtagaactcg ctgctatcaa tattcacgtt
    30901 gcaggtatcg tcccagataa aacaccaaaa ccagaattga aagatctatt tgacgaggac
    30961 ttcctcaatg actagtccac tattagaatc tagacgccaa ctccgtaaat gcgcttttca
    31021 agctctcatg agccttgagt tcggtacgga tgtcgaaact gcttgtcgtt tcgcctatac
    31081 tcatgatcgt gaagatacgg atgtacaact tccagccttt ttgatagacc tcgtttctgg
    31141 tgttcaagct aaaaaggaag aactagataa gcaaatcact cagcatttaa aagcaggttg
    31201 gaccattgaa cgcttaacgc tcgtggagag aaacctcctt cgcttgggag tctttgaaat
    31261 cacttcattt gacactcctc agctggttgc tgttaatgaa gctatcgagc ttgcaaagga
    31321 cttctccgat caaaaatctg cccgttttat caatggactg ctcagccagt ttgtaacaga
    31381 agaacaataa aaagaaaaag tgtttgatag atatcaaaca cttttttctt tgcctcccac
    31441 tatctaaaaa aatgataata gatataattg taaacaaaaa tccagatagg ttttgcatga
    31501 ttgagaaagt taaaaaaact atggcagaga atcgttaatc tcagattgtc ggtagaacga
    31561 taaacaaggg caaaaaagaa accaatcaga ctataatata ataaactaat tggatctctg
    31621 tgagatagta tcaaatggct aatcccaaag atgatagcag ataggataac atccaaatag
    31681 tacttggact agggaaagaa ggtattcata aaataccctc tatcaagagt ctcctcaaaa
    31741 acaggaccga tgattacagg caggacaaaa gataagatag tcgataaaaa ggttggttgt
    31801 ccatttgaaa aaagcacggt aaaatactca tcatgaatat tcctatgatt aatcaaatga
    31861 gcatagcgtg cccaaaaatt accgagaatc tgataaacca cataagttgc aaataagtag
    31921 aagacaaatg accagttcca gctctttttc tcaaagataa agagcatctt tttctttttt
    31981 aacctccaaa ttatatagaa ggaaacttcc cactaatccc attgttaaaa taagagaata
    32041 gacatcagct cctaacccta aaatgatcgt cacatacaat ccaattgttt gtggtaaata
    32101 ggtagatagt aaaataataa gcaaaaatat tccaaattgt cttagttttt ttgtgtttct
    32161 catcgtactt ttttgaaaga ttaccctgct cggaagccgt acttccaagc atctatataa
    32221 gaattaagtg ccccttgcct catataggga gcaaattctc tataatataa ccatctacta
    32281 tatccatctt cccaaacagc aagaccacct gaagtttgct ccaagtcctc agttgaaaga
    32341 actgtaaatg tatttgtacc tgtcattgca agtaccttct taaaatagat tgttgtaggc
    32401 tcacatttat agtatatttc tttttttgtc tattttatag cccatctcct caactggcaa
    32461 tttttcgacc tgaattacat ttttccataa aaaatgagac ctttctagtc tcatttagtc
    32521 attcttagta ttttctaaat cgttgatagc gttcttccag caactcttct agcggttttt
    32581 gtgaaagtct agccagctcc gtttggagtt cttttttgac actcttaatc agttctttac
    32641 tagaaagtcc tatttcagaa atcaccttat ccaccacgtc catttctaac agttcatgcg
    32701 aagtgatttt catcagttct gctgcttcca tggcgcgagt accgtccttc cataaaatgg
    32761 aagcaaagcc ttctggactg agaatggcat agatagaatt ttccagcatc cagacacggt
    32821 ccgcgacagc tagagccaga gccccgcctg aaccaccttc accgataata atggcgataa
    32881 taggaacttt caggtcactc atttccatga gattgcgagc gatagcttcc ccttgaccac
    32941 gttcttctgc tccgacacca ggataagcac ctgctgtatt aataaaggtc acaactggac
    33001 ggccaaattt ctcagcctgt ttcatcaacc gcagtgcctt tcggtagcct tctggatgtg
    33061 gttggccaaa attccgtttg aggttgtctt gcaaactctt gcctttttgg ataccaacaa
    33121 ctgttacagc ttggtctcca agccaaccaa taccaccaac aactgcacca tcatcacgaa
    33181 aagaacggtc accatgtaat tggataaatt catcaaaaat gcctgtcgca aagtccaagg
    33241 ttgtcaagcg actctgctca cgcgcttctc tgactatttt tgcaatattc atctaggact
    33301 ccctccatgc aatctgacta ggctagcaat cgtatctggt aagtctcttc ttttgacaat
    33361 agcatccaca aagccatgtt ctaataggaa ttctgccttt tggaaatcct caggcaagct
    33421 ttcacgaacc gtattttcaa tcacacgacg cccagcaaaa ccaaccaagc tctgtggttc
    33481 agccagaatg atatcgcctt ccatagcgaa agaagctgtc acaccaccag tcgttggatc
    33541 tgtcaaaatg gtcaggtaaa agagaccagc atttgaatga cgtttaaccg ccgcagagat
    33601 cttagccatc tgcatgagac tcatgattcc ttcctgcata cgggctccac cagaggctgt
    33661 gaataggaca actggcaatt tttcgacagt cgcatactca aacaaacgag tgattttttc
    33721 acctacaacc gtacccatag aagccatgat aaagttagaa tccataatcc caagagccac
    33781 agtctgacct ttaataagag cagttcctgt cacaacggct tcatgcagac ctgttttttc
    33841 acgcatagat gccagtttct tttggtaacc agggaaatgc aagggatcct tgctttcaat
    33901 ccctgtaaac aattctttga aggttcccat atcaatcgtc aaagccaagc gttcttgggc
    33961 agaaatacga aaggtatagc tacagtgcgg acagatacgt tcacttccca gatccttctg
    34021 atagatggta tgcttacagc ctggacactg ggaaaataat tcatctggaa cctctggctt
    34081 agcttgaggt ttttccctaa ccgaacgatt gggattgatt cgaatatact tatctttttt
    34141 actaaataga gccattgatt ccccttttcg gtttaaactc ttaaagtcat tttattcttt
    34201 ttcttgatat ttaggtaaga aggtttccat caagaaggaa gtatcataat ccccagcaat
    34261 gacattgcga tctgaaatga ggtcaagctg gaaatctgca ttggtctgca ctccttcaat
    34321 ctctaattca tagagggcac gttgcatttt catcaaggcg tcaaaacgat tttcgccgtg
    34381 tactatgatt ttggcaatca tactatcata ataaggcgga atggtataac ctggataaac
    34441 tgctgaatcc acgcgcaagc caactccacc acttggcaga tagagattag taatcttacc
    34501 tggacttgga gcaaagttaa aggctgggtt ttctgcattg atacgacact cgatggcatg
    34561 accgcgtagg acaatatctt cttgcttaac agacaaaggc tgacctgccg caatgcaaat
    34621 ctgttcctta acgatatcaa cacctgaaac aaactctgtt actggatgtt ctacctgaac
    34681 acgagtattc atctccatga aatagaaatt gctacttgct tcatcaagaa gaaattcaat
    34741 ggttcctgca ttctcatagc caacaaactc tgccgctcga acagcagcag cacctatttc
    34801 atgacgcagc gtttttccga ttgcaatcga gggactttct tccaaaacct tttggttatt
    34861 cctttgaaga gaacaatccc gctcacccaa gtgaatcaca tgtccatgct catcacctag
    34921 gatttgaacc tcaatgtgcc gagctggata gataacccgt tctatgtaca tggcaccatt
    34981 gccataattg gccttggcct cactagaggc agtttcaaag gcagaaacga ggtcatctgg
    35041 tttttcaacc ttacgaatcc ctttaccacc tccacctgct gaagccttga gcataacagg
    35101 atagccaatt ttttcagcaa caatcaaagc ttcttcagag ttatgcactt ctccatctga
    35161 acctggtata acaggcacac ctgctttaat catctgagca cgcgcattga tcttatcccc
    35221 catcatatcc ataacatgac cagatggacc gataaacttg atacctactt cttcacacat
    35281 ggtcgcaaat ttggaatttt cactgagaaa tccaaaacca gggtgaatag cttctgcctc
    35341 agtcaagact gcagctgata gaactgcatt aatattgaga taagactctg ttgccttgcc
    35401 aggaccaata caaactgctt catctgccaa aagcgtatga agagcttcct tatcagcagt
    35461 tgaataaacc gctaccgtcg caatccccaa ttcacgtgcc gcacggataa tacgaaccgc
    35521 aatttcacca cgattggcaa ttaaaatttt tcgaaacatg gagaacctcc ttagttccca
    35581 attgcaaaag taaggatacc actggctgca agcttgccat ccacttcagc ctttgcttca
    35641 accacagcta tggtgccacg acgttttaca aaagtcgctg tcataaccaa ttggtcgcct
    35701 ggtacaactt gcttcttgaa cttaaccttg tccataccag cgtaaaagac cagttttcct
    35761 ttattttcag gttttgataa ctccaacaca ccagcagttt gcgccaaggc ttccataatc
    35821 agaacacctg gcataactgg gtattgagga aagtggccgt taaagaaagg ttcgttaatg
    35881 gtcacatttt tgatagcaac aatggtatcc tcgctcactt ccaagacacg gtccactaga
    35941 agcataggat aacggtgggg aagagcttct ttgattcctt gaatatcgat catttgatac
    36001 gtaccaatcc tttaccaaac tcaaccattt cttcgttaga gacgagaatt tccgttacca
    36061 caccatcctt aggagctggg atttcattca tgactttcat ggcttcgata attaccaatg
    36121 tttgaccttt tttgacacta tcaccaactg taacgaaggc aggtttatct ggtccagcag
    36181 ccaagtaaac cactccaaca agtggactct ctacaagatt tccctcacta gccacacttg
    36241 cttcagctgg agctggaact tcttctgcta cagtctctgc tggagcagat gtaggagcta
    36301 ctggactcgg tgttgctaga acgggtgctg gagcgacttg agttgcaact tcaggcacag
    36361 gtctcgcttc attcttgcta aactgcaact catccgtccc atttttataa gaaaattctc
    36421 tcaaacttga ctggtcaaat tgagtcatca agtctttaat atcgtttaaa ttcatactta
    36481 tctattctcc caacgtttga aagcaagaac tgcattgtgg cctccaaaac caaaagtatt
    36541 tgaaatagcg tatggaattt ctttctccaa gccttgtcca taaacgacat tagcttcgat
    36601 ataatctgat acttcacttg tcccagctgt cattggtaca aagttatgac gcatagcttc
    36661 gatggtgacg atagcttcta ctgcacccgc agcccccagc aaatgtcctg taaaagactt
    36721 ggttgatgat acaggtactt ccttaccaag aacagctacg atagcaccac tttctccttt
    36781 ttcattggca ggagttgacg ttccgtgagc attgacatag gctacttgct ctggagaaat
    36841 ctcagcttct tccaaggcta gtttgatggc cttgatagct ccctgacctt ctggatgtgg
    36901 agaagtcatg tggtaggcat cacaagtatt tccgtaacca accacttcag ccaggatagt
    36961 agctccacgt ttttcagcgt gttcaagact ttctagaacc aacatccctg aaccttcacc
    37021 cataacaaac ccattgcgat ccttatcaaa tgggatcgaa gcacgagttg gatcctctgt
    37081 agtagagaga gctgttaagg cttggaaacc agcgatggca aaaggtgtga tagaagcttc
    37141 tgttcctccc accaacatca catcttggaa accaaactta atggagcgga aggcatcccc
    37201 aatcgcatca tttgatgaag agcaggcagt attgatagat ttacaaacac cgtttgcacc
    37261 aaaacgcatg gctacattcc cagaagccat atttggtaaa gcttttggaa gagtcattgg
    37321 tttgacacgt ttgggtcctt tttcatgaag gcgaagtacc tgatcttcaa tttccttgat
    37381 tccaccaata ccagatgcaa cgataacacc aaaacgatcc ctattaagag cctctacatc
    37441 aagattggca tgatttacag cctcttgggc tgcatacaag gcatataaag aatagttatc
    37501 aaaacggttg gtatcttttt ttacaaagta tttatcgaac ggaaaatctt ggatttctgc
    37561 cgcattatgc acatcaaagt cactatgatc aaattttgta atgccaccaa tgccgatttt
    37621 cccagttgct aaactattcc aaaattcttc tggtgtattt ccgattggag atgttactcc
    37681 ataacctgtt accactactc gatttagttt cattcttttc acctctagct ttcgctacat
    37741 acttaagcca ccatcaatgg caaccacttg accagttaga taatcttggc ctgctaaaaa
    37801 tactgtcaaa tctgcaacct gctctgcctg cccaaattct ttcatcggaa tctgagctag
    37861 tgtagcttcc ttaatcttat ctgataagat agctgtcata tcagactcaa tcattcctgg
    37921 agcaatcaca ttgactcgta tattccgact agcgacctcg cgtgccacag acttggtaaa
    37981 gccaatcaag ccagccttag aagcagcata gttagcttga ccaatattcc ccatcaaacc
    38041 aacaacacta gacatattaa tgatagcacc ttctctggct ttcatcatcg gtttcaagac
    38101 tgattgtgtc atattaaagg caccagtcag attgaccttg agcacttttt caaaatctgc
    38161 ttctgtcatc ttgagcataa gagtatcttg ggtaatccct gcattgttga ccaaaacatc
    38221 tactgaaccc agttctgcaa tagcttgatc aatcatacgc ttagcgtctg caaaatctga
    38281 tacatctcct gaaatgggaa ccaccttgat accatagttt gaaaactcag cgagcaattc
    38341 ttctgagatt gccccacgac tgtttaagac aatgttggct cctgcttgag caaacttgtg
    38401 ggcgatggca agaccaattc cacgactcga acctgtaata aagatatttt tatgttctag
    38461 tttcattttt ttcctttcaa aacttctact tattttagtc tatttttcta aaagtgctac
    38521 taaactcgct tgatcttcca catgagctaa gtgagcagtt tgatcaattt ttttaacaaa
    38581 acctgacaag actttccccg gtccaatctc gataaagttg cttatgcctg cttcttgcat
    38641 gaccccaata ctttcataga aacgaacggg ttccttgacc tgacgcgtca agagctgagc
    38701 aatgtcctct ttttgcatca cagcagcttc tgtattgccg actaggggac aagtaaaatc
    38761 tgaaaaactt acctgagcta gagtttcagc tagtttctgg ctagcaggct caaggagagc
    38821 ggtgtgaaag ggccctgaca ccttaagagg aatcaagcgt ttggcacctg cttcttgcaa
    38881 aagttcaacc gctcgatcaa ctgcaaccac ttctccagca atgacgattt gtgcaggtgt
    38941 gttatagttg gctggagtaa ccactccaag ttcagaagct ttttgacagg cttcttcaat
    39001 gacctctact ggcgtattga gaactgctac catcttgcca gagtcagcag gagccgcttc
    39061 ttccatatag gctccacgct tagctaccaa ggcaaccgca tcttcaaaat ccaaggcgcc
    39121 gcttgccacc aaggcagagt attctccaag agacaaacca gcaaccatat caggctgata
    39181 gcccttttct tgcaataaac ggtagatagc aaccgaagtc gctagaatgg ctggttgcgt
    39241 atagcgggtc tgattgagtt tgtcttcttc cgtatcgatg agataacgta aatcataacc
    39301 gagcacctga ctcgctcgat caatcgtttc tttgacaatc ggatactgat catagaaatc
    39361 ccgtcccatc cctagatact gggcaccttg accagcaaat aaaaaggctg ttttagtcat
    39421 ttcttacaac tcctgcccag cgagaggctt cttcttgaat tttcttagcg gctccgtaat
    39481 acaaatcttt taggatttct tcagctgttt cttctttaga aacaagccct gcgatttgac
    39541 ctgccatgac agagccacca tccacatcac cgtgaacaac tgctttggct agggcacctg
    39601 ctcccatttg ttcaaagatt tctaaatcag gatcttcctg cttaaaggca tctttttcag
    39661 ccagttcaaa atctctagtc aactgatttt taatagcacg aacagcatga ccaaagtgct
    39721 gagctgaaat cgtagtatca atatcccttg cttttaaaat tttctccttg tagtttggat
    39781 gggcattcga ctcttttgca actacaaacc gtgtccccac ctgtacagcc tctgcaccta
    39841 gcataaagcc agccgcagca ccttcaccat ccgcaattcc tcctgcagca ataacaggaa
    39901 tagatatagc tgtggctacc tgtcgcacca aggtcatggt tgttaattta ccgatatgcc
    39961 ccccagcttc cattccttct gcaataacag cgtctgcacc gattttttcc atgcgtttag
    40021 ctaaagcgac actaggaaca acaggaataa cgattatccc agcttcatgg aaacgttcca
    40081 tatacttgct tggatttcct gctcctgttg tgacaacttt aacaccttct tcaataacga
    40141 gatccacgat atcttccaca aagggagata agagcatgat gttgacccca aagggtttat
    40201 cagtcaatga tttgatttta tcaatattgg ccttgacaac ttctttcggg gcatttcccc
    40261 caccgataat tcctaatcct ccagccttgg aaacagcccc tgccaaatca ccatcagcaa
    40321 cccaggccat ccctccttgg aaaataggat agtcaatctt caataattct gtaatacgcg
    40381 ttttcatagt gcctccaacc ttccttgctt acgtaatagt tcgatttcac cataatttga
    40441 cagtcaaact attacctaaa caagagggag tgggtttctc cctactcctt ctactaatat
    40501 tctgcttatt ttgcttgctc ttcaacgtaa gcaaccaagt caccaactgt tttcaagtca
    40561 ttttctgctt cgatttggat atcaaaagca tcttcgattt ctgagattac ttggaacaag
    40621 tccaatgaat ctgcgtccaa atcatcaaaa gttgattcaa gtgttacttc tgatgcgtct
    40681 tttccaagtt cttcaacgat aatttcttgt actttttcaa atactgccat gataggactc
    40741 ctttaaaata aatagttttt ttataacaat gtgttcacca catgattacc taaattgtaa
    40801 gaatgagcgt gccccaggtc aagcctccac cgaagcctga tagaagaaca gtctggctac
    40861 catctaaagg gatgagacct tgttctacac actctgaaag taaaatcggg atactggctg
    40921 cactggtatt gccatattcc atcatattgg ctggaagttt ggctcggtca acaccaattt
    40981 ttctagccat cttatccaaa atacggtcat tggcttgatg aagtagcaga taatccaagt
    41041 ctgtcacctc tataggagat tcatcaatag tctgcttgat agacttggct acatctcgaa
    41101 tggcaaaatc aaagactgtg cgtccatcca tcttcaaaaa cgaatctgca ctttcttgat
    41161 ctgaaaatgg agaatgcaaa cctgaatgcc cataagttaa acactcgctg cgacttccat
    41221 cgctattgag actctcagct aagaaatgct cttgctcgct agcttctaac aagacaccac
    41281 cagcaccatc tccaaacaac acagctgttg atcgatccga ccaatcgact gccttagaga
    41341 gggtttcact accaatcacc aagccttttt gaaagcgacc agaagcgata aacttttcag
    41401 cagttgaaag agcaaataca aatccactgc aagccgcggt taagtcaaaa gcaaaggctt
    41461 tattagcgcc aatattagct tgaacacgag cagctgtaga gggcatcatc gaatctggag
    41521 taatggtagc taggatgata aaatccagtt cttttcctgt tattccagct tttgccatca
    41581 gtttcttagc aacctctgta gccaaatcac tggtagattc tgttcttgaa atatgccttt
    41641 gtcgtattcc cgttcgactt gaaatccact catcattggt atccataatc tgagccaagt
    41701 cgtgatttgt aaccacttgc tctggcacat aatgagcaac ctgacttatt tttgcaaaag
    41761 ccattatttc aaatcctcca aaaattggta aagattagtc aagcctttac ccatgacagc
    41821 aatttcttcc tcgctcatgc catcaataat tttttctacc atggccttgt ggaagcgttt
    41881 atgcagtcta tgaatcaagc gacccttctt tgtcaaatgc agatgcacca cacgacgatc
    41941 ctgttctgac cgaactcgct caatgtagcc cttacgctct aaattgttca aacttgtcgt
    42001 aacagttcca agagttacca tcaactcttt tgacacttga cttggagtca catctggagc
    42061 cttaccgatg acatcaatcg tatgcatttc tttgatggag atatccttaa aacgactacc
    42121 tctcaagttc acttcctcaa ttacaaggac attgttaaat atagatgtta aatattcatt
    42181 gattcgttgg tagtccattt ttcatatccc tccttcttca aaaaactttt acaatcaaaa
    42241 catttgacag aaagaattat atcaaaattc aaagaatgat gcaagtattt tttattttcc
    42301 tgtaaattta ggtcttcttc tctccgaatg agctcgcact ccttctttga aatcctctgt
    42361 ttgagctaag gatttctgta ggttcagttc taaagtagcg taaccctgcc agtctttaaa
    42421 ctggctctcc caaaccaact tcttaatggc agcataggaa ttacttgaag cacgtcttaa
    42481 ttttttaaga agctgttctc tcgtcttttc aagtttttca gcttcagaaa cgcggtaaac
    42541 caacccccat tctagggctt tttctgccgt taaagcctct cctgtcatag ctaattgagc
    42601 agcacgcgtc acaccgatac tgcggctcaa gagatgaatt ccccctgcat ctggagccaa
    42661 accaacacca acaaaggctt ggataaactt agccttatcc gtcgccaaac agaaatctgc
    42721 cgcaacagcc atattcgctg cggcacctgc aacagcaccg tcaacttcca ttaaaacagg
    42781 tttggctatt tgcttgattt tataagaaat cgtattgacc aactctgcga tttttgtcaa
    42841 tgatggaata tcatcctcat ccactgcccg cttcatctct accaaatctc ccccaactga
    42901 gaagaccttt ccattggcat tgattaagat aaaatgcaca gctggatttt cttctgccaa
    42961 agtcagagct tctaaaatct cctcacacat gggaatatga aaaccatttg cgacctcagg
    43021 acggttcaag gtaaggattg ccaagtcctc ttcaagctga taaataatgt gttccatcag
    43081 ggctcctttt tattttataa gcagtttata ctcttcgaaa atctctttaa accgcgtcag
    43141 cttccatctg caacctcaaa acagtatttt gagctgactt cggctagctt cctagtttgc
    43201 tctttgattt tcattgagtg ttaaattatt tcactgtcaa agtatatctt ttttaggagc
    43261 agaaagcaag aaaaaatcga ctgaaagtgt ctcagccgat aagaaaggct cgctttaggc
    43321 tagaaagcat cttattttct tcattgaaaa aagcctttct ttctgctata atcgtataaa
    43381 atacttactt taggagttct tatgaaagtt gttaaatttg gaggtagttc tcttgcctct
    43441 gctagtcaat tagaaaaagt tttaaacatc gtcaaaagcg attcagagcg tcgttttgta
    43501 gtcgtttctg cgcctggtaa acgcaatgct gaagatacta aggttacgga tgccctgatt
    43561 aaatactacc gcgactatgt tgcgggtaac gatattagca agagccaaag ctggattatc
    43621 gaccgctatg ctgctatggt tagtgaattg ggactaaaac cagctgtgct agaaaaaatt
    43681 tctaaaagca ttcacgcctt ggccactctt cctattgaag aaaatgaatt tctctacgat
    43741 actttcctag cagccggtga aaataacaat gccaaattga ttgctgccta ctttaaccaa
    43801 aatggtatcg atgcacgcta tatgcaccct agagaagctg ggattgtggt cacaagtgaa
    43861 cctggtcacg ctcgcatcat tccatcaagt tatgacaaga ttgaagaatt gacaaacacc
    43921 aatgaagtcc ttgtcattcc tggtttcttt ggtgtcacta aggaaaatca aatctgtact
    43981 ttctcacgtg gaggttctga tattacaggt tctatcattg ctgctggtgt caaagctgac
    44041 ctctatgaaa actttacgga cgttgatggt atctttgcag cccaccctgg tattatccac
    44101 caaccacact cgattcctga gttgacctac cgtgaaatgc gcgagttggc ctatgcaggc
    44161 ttctcagtcc ttcatgacga ggctcttctt cctgcctacc gtggaaaaat tcctctggtt
    44221 atcaagaata ccaacaaccc tgaccatcca ggtactcgta tcgttctaaa acacagtaat
    44281 gatgaatttc cagttgtggg aattgctggt gactcaggct ttgtcagcat taacatgtcg
    44341 aaatacctca tgaaccgtga ggttggattt ggccgcaagg ttctgcaaat cctggaagaa
    44401 cttaacatcg gttgggaaca tatgccaaca ggtatcgacg atctttctat cattctccgt
    44461 tctcgccaac taactcccat caaggaagaa gaaatcctgc gtcagttggt tcaaaaggct
    44521 aaagtagatc atgcagaaat cgaacacgac ctttctatca ttatgattgt tggtgaaaaa
    44581 atgaagagcc acatcggagt gactgctact gcgacacgcg ctctatctga aaacaaaatc
    44641 aacatccaga tgatgtctca aggttctagt gaagtttcta ttatgtttgt tgtcaataaa
    44701 gaccaagaga aagcagcaat taaagccctc tacaatgcct tttttggaga aagtaaggaa
    44761 gactaagcat ggcccaatca cttaacaaaa cagtactcct cagtacgaca ggcacttcct
    44821 acctctctat cgctgggaaa gttgggaaat tccttgtcgg agatcaggct ttggaatttt
    44881 acccagatgt caatgtcgaa caatttatcc agattccttg gagccatatc aatcagattg
    44941 gagccaatgt cactggatgc aaaatcagcc gccacttcga agtctttaca gacaaaggaa
    45001 aattcctctt tgcttcaaaa gactcaggtg ccattctcaa aattgcacgc gaaaaactag
    45061 gcaatgacaa ggtcgtcaaa cttccgaccc tgattcagac aattagccaa aaatttaaaa
    45121 atctatttgc aaaaaagtag aaactttagt ataatcatag caacggataa gtaggttatc
    45181 ttcttctttc agaaagtctg cgggtactgc gagcagatag gagggatagg tgaaattcta
    45241 ccgttagtaa caattacata cacaatcaag tgcacacctg tgaagttgga tggaaccgtg
    45301 gccctgccac tccaacgttt tgtcaggcgt gcttttttca taaaggagtt cttatgttag
    45361 atatcaaacg tattcgtaca gattttgaag ctgtcgcaga aaaattagct acacgtggtg
    45421 tagatgctgc tgtcttgaat gaaatgaaag aaatcgatgc taaacgtcgt aacatcttgg
    45481 tcaaggttga aactctcaaa gcagaacgta acacagtttc tgctgagatt gcccaagcta
    45541 agcgcaacaa ggaaaataca gatgacaaga ttgctgccat gcaaaatcta tctgctgagg
    45601 ttaaagcctt ggatgctgaa ttggcagaaa tcgatactaa attgacagaa tttacaacga
    45661 ctcttccaaa tatcccagct gacagcgttc ctgttggggc tgacgaagac gacaatgtgg
    45721 aagttcgccg ttggggtact ccacgcgagt ttgacttcga acctaaagct cactgggatc
    45781 tcggtgaaga ccttggtatc cttgactggg aacgcggtgg taaggtaaca ggcgctcgct
    45841 tcctcttcta taaaggcctc ggtgctcgtt tggaacgtgc tatctacaac tttatgttgg
    45901 atgaacatgg aaaagaaggc tatactgaag tcatcacacc ttacatagtc aaccatgatt
    45961 ctatgtttgg tactggtcag tatccaaaat ttaaggaaga tacttttgaa ctcagcgata
    46021 ccaactttgt cttgattcca actgctgaag ttcctctgac aaactactac cgtgatgaaa
    46081 tcttagacgg caaagatctt ccaatctact tcactgctat gagtccgtca ttccgttctg
    46141 aggctggttc tgccggtcgt gatacgcgtg gcttgatccg tttgcaccaa ttccacaagg
    46201 ttgaaatggt caaatttgcc aaaccagaag aatcttacga agaattggaa aaaatgacag
    46261 ccaacgctga aaacattctt caaaaactca accttccata ccgtgtcgtt gctctctcta
    46321 ctggagatat gggcttctca gctgcgaaga cttacgactt ggaagtgtgg attccagcac
    46381 aaaacaatta ccgtgaaatc tcaagctgtt caaacacaga agatttccaa gcccgtcgtg
    46441 cccaaatccg ttaccgtgat gaagcagatg gcaaggtgaa actccttcat accttgaacg
    46501 gttctggact tgcagttgga cgtacagtgg ctgcaattct tgaaaattac caaaatgaag
    46561 atggttctgt gaccatccca gaagcacttc gtccatacat gggtggagct gaagtcatca
    46621 aaccataaaa aataaggttt agctatttct agctagacct tttttcgtaa ccaaatcaga
    46681 taagcaccta gtacaaagaa taaaatagtt aggcatataa tggtttcagc caataccagg
    46741 taatccagaa atggaagttt caaaattccc tgagccatct tgagcgaggt cgctgtgata
    46801 atggttggga aggtgagggc tgagaaggct ggttgaaaac cttgttttaa aatgttgggc
    46861 agacgagtta aaacaaagaa aaagaaggat tgagaagcca aaatcatgac aatcaagacc
    46921 caagtcggca ggctggttcc tcctactcga actagagaag ccaagagtag agagaaagga
    46981 gcacagtaga ttccttcttg tccaagcaag gctagtggga gtggatgttt ctttaaatcg
    47041 ctataaataa ggggatagag atagaaggtc aagagaaaac caaaactcaa ggtcgcatag
    47101 gcaatttcga taatacctac cagaggatag gtcaaggcag ccactgctat ccccacatag
    47161 agaaccgtcc agcttggagt ggcatgaacc ctccgccctg gacaagcaaa cttgatggta
    47221 aaaccagcaa tcaaggtcaa atccaagaga aatgaaaacc accaaatccc ttgtgctacc
    47281 aaaggaagat aagagaatac gcgaaagaca taggtcgata aaatcatccc agccatagga
    47341 aaggttgcca ttcctgacaa aagagggggc ttggtcaatt cttgcttggt ttctttccaa
    47401 ttaaagagat gcagaattag aaagtaaatc cataaaacca aaccagtcag actaaaaaga
    47461 tgggatagaa ccggcaacgt atctaaaata agatttccag ctcctgccaa acctagcaaa
    47521 caacctgaaa atactaaggg gagttttttc atcctaacct ccaataatca tgttagtttc
    47581 agtataacat aaaagcgctt aaatgaggat ttaaaaaaac gaagtccgct tatttcagac
    47641 ttcattttac tcagatatga attaggcata aggttgcaat tctggattaa ttggtgtatt
    47701 agctaagttg ttggcatagt tacagaggat tgctaggctg acaccaaaaa ccacatccaa
    47761 ggcattttgt tgagtgtagc cagcttctaa aaactcagac aaggcttcat ctcctacacg
    47821 acccttggta ttgataactg ccaaggtaaa cttagctagg gtatccaatt taggatctgt
    47881 ttcaattgga gtacgattgc gaagagcttg aatcaagtca tcattcatct ggatttgttt
    47941 gatggaaaag gctgtgtgac ctgcgacaca gaaggcacaa ccattggtca cggctgccgt
    48001 gatttgcacc acttcacgct caacgggtgt caggctgttg cgacggtgga tagatgagac
    48061 aatttggtag gcttctaaaa cagtcggggc attggccaag agaccgatta ggttgggaat
    48121 atagccattg ttgtcttttt ctactgtttc aagaatttct ttcacttctg ctggtgctga
    48181 ctctactgta tggatagtaa atgttgtcat aagatacctc ttttcttatt attgacacta
    48241 atattattgg aaaatcttat aaaatcctga ttcctaagtt tatctaagat aaagctttat
    48301 tctctcataa gattttcgtt gttatattag tttatcacac ttccaatcac ttgcataata
    48361 tatattatat atcaggctga taaaaattat ttataggcaa aaaaatcaca cgagctgtgt
    48421 gattccatta tttgtcaaaa tactttttag tttcagcaat aacgactggc gacaagacca
    48481 agagggcaat caagtttggc agagccatca aggcgttaac gatatctgcg ataatccaga
    48541 ccatatccaa ctcgataaat cctcctaaca agaccatgag cacaaaaacc acacggtaga
    48601 gccagataaa gcgaacccca aagaggaact caaaacagcg ttctccgtaa tagttccaac
    48661 ctagaatcgt tgtaaaggca aaaagtacaa ggaagatggt caagagggca ggcccaaagt
    48721 gtgaaaagac tgttgagaaa gctgactgag tcaaggcaac cccattcaag tcaccactcc
    48781 aaactccagt taccaagatg gtcaaaccag ttagagtaca aatgatgagg gtatcaataa
    48841 aggttcctgt catggaaatc aaaccttgct ctactggttc atttgtcttg gcagctgcag
    48901 ctgcaatagg agcagaaccc agaccagatt cgtttgagaa cacaccacgc gccacaccat
    48961 tttgaatagc catccgaacg ctagcaccag caaatccacc taccgcagca aggggactaa
    49021 aagctgaggt aaagactaaa gcgattgtgc cagggatttt tccaatatta aagaaaataa
    49081 ctgtaagagt tcctaagata taaatgatgg ccataaaagg aacaacagta gttgaaacct
    49141 tagaaataga cttgagtcca ccaaagactg caatcgctac aaagacagac aagacgagag
    49201 ctgtgatggc tggcgaaatc gtcgttgtat tttggataga ttctgcaatc gagttgactt
    49261 gggtgaaggt tccgattccc aagagagcaa ccaatactcc tgctactgca aacaaaacag
    49321 caagtggtcg ccacttttct cccatcccta gaaggatata atgcatggga cctcccgcta
    49381 ctgcaccatg gtcgtccttg gtgcggtatt tgatggccaa gagtccttcc gcatacttgg
    49441 tagccattcc aaagaaagcc gccatccaca tccaaaatag agctcctggt ccaccaacct
    49501 tgatagccgt cgcaactcct atgatatttc ctgttccaac agttgatgcc aaggctgtac
    49561 acagagctgc aaaactggat acatcaccat gtcccttatc ctggataaaa ataagctgaa
    49621 aagccttggg cagacgcaaa acctgcaaga gtcctagccg aatagttagg taaatccctg
    49681 ttccgaccaa taaaatcaag aggggcggtc cccaagcaaa agcatcgatt gatttaagca
    49741 attctaacat ttccttctcc tatcgtttca accccaaaag aaagagcaca tgcaagatac
    49801 atgtactctg gaatgcttag ataaatgcta aaaagcggtc tatcctagct ctgtcctttt
    49861 acctgagagt ttgagcagtt gcctgccttg ccccttcggt gcctttacgg tctctccaga
    49921 gttccgtcca tttacagtca tggaaaatca aacgattccc cacttctatt aaacttcatt
    49981 cggtgttggt atttaattga ttctaatttt acaaaaaatg ttggcttttg tcaatgtgtt
    50041 tattagtaaa aattagttca acagttttta ctttataaag tccagaatac tgctatcctt
    50101 taaaagtgac aatagtcgca ccactgcctc cagcattttg tggggcatag ccgaaactct
    50161 tgacatgttt gtttctttgc aagtatttgg taactccttc acggatgact cctgttccga
    50221 taccatggat gatatcaact tgagccatat tgttaagcaa ggcttggtcg atgaagatat
    50281 ctagctcatt catggcttct tcatagcgct tgcctcgaag atccagtcta gcttgaggtc
    50341 ctcgcccaga agttcgtttc acaacattga cctgcttctt cttgactggt ttttcttgct
    50401 gggcttgaac aagatcaaac tctttctctt ccaaggtcat cttaatcaag ccaacttggg
    50461 cttcccagcg gccgtccttg agttgactgg tcaaggtacc acgctgacca taactgagaa
    50521 ccacgatatc atctcccacc tttggagctc gttttttctt ggccttttga aggaccttgt
    50581 ttttagacaa gtccactttt tcaggagcca attttttcaa cttggccttg gcttcaatga
    50641 tttcgtgggg cttgagttgg gatttactgt ggagattttt gagaatctgg tcactttcac
    50701 ttagggccat atccacaatc tcagcagcct gttcacgcgc cttgttaagc tcggtttcct
    50761 tttcacgatt aagctcgttg tagagttttt ttagcgcacg gttcatcttg agattttctt
    50821 gctccacctc acggatattg tccaaacgtt tgcggctttc cagcgtctgc tcttctaatt
    50881 gctcaatgat acgattgacg tcattgtcct gatcgatctg ctgactggca tctcctacga
    50941 taacttcaga taggcctaga cgtttggcaa tttcaaaggc attacttcgg ccaggaacac
    51001 cctgcataaa gcgataggtc gggcgaagag ttgcagtatc aaactccata ctggcatttt
    51061 gcacaaaggc tgtctcaata ccgtaggcct tgagttctgg atagtgggtc gtcgccatgg
    51121 tcttgatttg acgcaggcga aggtcctcca gaatagccat ggcaagggct gctccctctt
    51181 ggggatcagt accagccccc agctcatcca aaagtaagag tgaatgttgg ttgaccttgc
    51241 caagaatatc cacgatattg gtcatatggc tagagaaggt agacaagctc tgctcaatag
    51301 actgctcatc tccaatatca gcaaagattt cttcaaaaat accaacacga cttcccttgt
    51361 ctgctaaaat cggcaatcct gactgggcca tgacctgtgt caagcccaga gttttaagca
    51421 tgatggtctt cccacctgta ttgggacctg taatgacaat agctgttaaa tcttgaccaa
    51481 aatggacatc atttgcgacg gcatttttga ccaaaggatg gcagacatgg agcagttgaa
    51541 tctcttgatt ttctgacagc tgaggcacga ctgcttgtct ttcttggata aatcgaacct
    51601 tggcacgaat caagtccaga tgaccgataa tccaagcgtc attagcaatc tcagccgcat
    51661 gagggcggac acgctcagaa atttcttgga gaatgcgaag catttcatag cgctcatctg
    51721 ctcgcagact agcaatttct tcgctcagtt tgactacctc acgtggttcg atatagacgg
    51781 tgtttccact agcagaaata tcatgaacga cacctgcaat cttattgcgg taggtgtttt
    51841 tgactggtaa aacctgacgg ccatttctgc tagcaacaat tccttctgtc aacatctgcg
    51901 ctttttgctt gagcaagtct tgtaaaacat cgcgtacctg actctcgcta tcatgtattt
    51961 ttcgacggat tcgcgccaat ttttcactgg caaaattttc aatgaaaccc gcatcattaa
    52021 aggcctgaag atttccttgt aattgcggaa aatcatgtaa tttctcaaac caaagggcta
    52081 attcttccaa gctgacattt tccagattgg cgtaaaaact ttgaagttct cggctggcaa
    52141 gaagcacgcg tttcaagagt aggaactcct cgatattgag atccgctccc atctccaacc
    52201 tcttgcagac tcctgcaatt tccttagttg agagaatagt aaaatgcggt tgctcgacga
    52261 aaagagcctg catttccttc atctcagcaa aagcctgttt gattttatct gctttggcag
    52321 tcggagccag ttgtctcaat tgctccaagc cctgctcggt caacaaatga ggctcaaaca
    52381 aggccttgac cttatcgaac tctaatgttt ctaatatttt cttattcatc tttatttcct
    52441 tgtctttgaa tgtctaggtg tggtagcttt ttacattctg atagattcga gtcaaatctg
    52501 taaacaaagg gctaggaaaa ctcctgccct ttttatccga ttaaatttgt cacccagatt
    52561 tgtttgagcc aactggttgt tatcggtatg ctctggatga tgtgttttgc gacgatactc
    52621 ttttcaagag gattttgtat aactgccatg gggatggtcg ccaagattgt caaggccatt
    52681 tgcaagacaa ataaggtcac caacatggac aagatacctg ctgaaacttg gaacaactta
    52741 ccacccagtt ttttgctagg aatcaagtgt aagagaagac caagcaaacg accaatgcta
    52801 tagacaatcc caaatacaag caagtagccg atgcctgcat aaaagacctt atccagctga
    52861 aagagttgat ccgatgggaa aaagaaagtc ccctgacctt cctgcgaatt tgcataaggg
    52921 agcaataaat ggaattgctc tccaagcccc ttataaaact ggccagccat aaaagccgat
    52981 gccatggctg aaatcaggta ataaacctgt aagagcaggc ctctccgata gccgatataa
    53041 aatccccaaa ccaagaccaa tagaagaagg aatgaaatca taaggaatcc tcaatcttgc
    53101 tctgttcttg cttacaagtc acaagcttgt gacggagttc ttctagctct tgctccttat
    53161 cgtcaaattc aatctcacgg ctgagctgag ttgataaaca gttgactgcc aacaaaagag
    53221 cgattgtttc atcatctgcg ctaggcattt gttctttaat tgcttggtat ttttctgtcg
    53281 caaccttagc gatttcctcc ataaaaaggt tatcatgttc gcttgtcaag gttaacgatt
    53341 ttttcccgaa tgtaaatttg aatcgattta gatttgccat aaaattcacc tcacgatatt
    53401 ataccaaaat tcgctaattt tgtcagtttt tacaaatttt actgcttttg tggtacaata
    53461 gaaactatgg caagtatcac actcacacca agcgaaaagg atattcaggc ttttcttgaa
    53521 cactatcaaa ccagtctggc tcctagcaag aatccctata tccgctactt tttgaaacta
    53581 cctcaagcaa cggtttctat ctatacttct ggaaaaatct tgcttcaggg tgaaggggct
    53641 gaaaaatacg ccagtttctt tggctatcaa gctgtagagc aaaccagcgg acaaaatctt
    53701 cctttaattg ggacagatga ggtgggaaat ggttcctact ttggtgggct tgcagttgtg
    53761 gctgcctttg tcacacctga ccagcacgac tttttacgaa aactcggtgt gggggattct
    53821 aagactctga ccgaccaaaa gatccgtcag attgctccta ttctcaagga aaaaatccag
    53881 caccaggcac tccttctctc acccagcaag tacaacgagg tcatcggaga ccgctacaat
    53941 gctgtttcgg ttaaggttgc cctccataat caggctatct atctcctcct tcaaaaaggt
    54001 gttcagcctg agaaaattgt gattgatgcc tttaccagtg ctaaaaatta tgacaagtac
    54061 ttggcacaag aggccaatcg tttcagcaat cctatcagct tagaaaaaaa ggctgagggc
    54121 aaatacttgg ctgtcgcagt ttcttctgtc attgcgcgtg atctctttct ggaaaatctt
    54181 gaaaatctgg gacgagaact gggttatcag ctcccaagtg gagctggaac agcttctgac
    54241 aaggtggcta gccagatttt gcaagcctat ggtatgcagg gactcagctt ctgcgccaaa
    54301 ttgcacttta aaaacactga aaaagcgaaa aaacgcttag aaaggtaagt tatgaattca
    54361 tttaaaaatt tcttaaaaga gtggggattg ttcctcctaa ttctgtcatt actagcttta
    54421 agtcgtatct ttttttggag caatgttcgc gtagaaggac attccatgga tccgacccta
    54481 gcggatggcg aaattctctt cgttgtaaaa caccttccta ttgaccgttt tgatatcgtg
    54541 gtggcccatg aggaagatgg caataaggac atcgtcaagc gcgtgattgg aatgcctggc
    54601 gacaccattc gttacgaaaa tgataaactc tacatcaatg acaaagaaac ggacgagcct
    54661 tatctagcag actatatcaa acgcttcaag gatgacaaac tccaaagcac ctactcaggc
    54721 aagggctttg aaggaaataa aggaactttc tttagaagta tcgctcaaaa agcccaagcc
    54781 ttcacagttg atgtcaacta caacaccaac tttagcttta ctgttccaga aggagaatac
    54841 cttctcctcg gagatgaccg cttggtttcg agcgacagcc gccacgtagg taccttcaaa
    54901 gcaaaagata tcacagggga agctaaattc cgcttctggc caatcacccg tatcggaaca
    54961 ttttaagaga cctaagaggc cgagaatcac caatctcagc ctcttcttct atcgtgagaa
    55021 gtgattgttt attgacaaat actcaacgaa aatcaaagaa caaactagga agctagccgt
    55081 aggctgctta aaacagtgtt ttgaggttgt ggatagaact gacgaagtca gctcaaaata
    55141 ctgttttgag gttgcagatg gaagctgacg tggtttgaag atattttcga agagtataaa
    55201 ataaaaacaa tcccaactct cacctattca tgcaaaggaa ttttatggaa gtttattttt
    55261 caggaaccat tgaacggatt atttttgaaa atcccagcaa tttttatcgc atcctcctcc
    55321 tagaaatcga cgatacggac gcagaggatt ttgatgattt tgaaatcatt gtcacaggaa
    55381 ccatggctga tgtaattgag ggcgaagact atactttttg ggggcaaatt gtccagcact
    55441 ccaagtatgg agaacaactg caaatcagtc gttatgatcg cgcaaaacca actagtaagg
    55501 gcttggtcaa gtacttttca agtagccatt tcaaggggat tggtctcaag acagctcaga
    55561 aaatcgtgga tacctatggc gaaaatacca ttgacgaaat tttgcaacac ccagaaaagt
    55621 tagaaggcat cgcaggactc tctgccaaaa atcgcgaggc tttcgtctcc actctccgtc
    55681 tcaactacgg aacggagatg gttttgtcca aactagccaa ctacggcatt cccaacaaac
    55741 tagcctttca gattcaagac ttttacaagg aagaaaccct tgatgtggtt gaaaattatc
    55801 cctaccagct ggttgaggat atcaagggtt tgggctttac cattgctgac caactagctg
    55861 aggaactagg catcgaaagt caggctcctg aacgcttccg cgccggtcta gttcacagtc
    55921 tttttcaggc ctgtatggaa acaggggaca cctatgttga agcacgggat ttgctggaac
    55981 aaacccttac tctccttgag tcttcccgtc ccgtggaact agaccccagc caagttgccc
    56041 aagagctctc ctacctgatc gaagaagaca aggttcagca gattgatacc aagatctttg
    56101 acaacagcct ctttttcgct gaggaaggca tccgcagtca cttggttcgt atccttgaaa
    56161 aaggaaaaca gaagagtcat gatttagaaa ccattcaaaa acatatcact actatcgagg
    56221 aagagctggg aattgagtat gataacattc aaaaacaggc tatctgtgat gctatccaga
    56281 ataaggtctt tatcctgaca ggtgggcctg gtactggtaa gacaactgtt atcaatggaa
    56341 tcatcgctgt ttatgccctg ttagagggac ttgacttcag gaagaaaagc aatctgccta
    56401 ttcttcttgc tgctccaact ggtcgagctg ctcgtcgcat gaatgaattg acaggtttgc
    56461 ctagcgcgac catacatcgc cacttgggaa tgacaggtga cgatgatacc agtcatctgg
    56521 aagattacct agatgctgac tttatcatcg tggatgaatt ctctatggta gatacttggc
    56581 tggccaatca actcttctcc aatatctctt ctaacagtaa gatcctcatc gtaggtgaca
    56641 gtgatcagct accttctgtc agtcctggac aggttctagc ggatctgctt catattcctt
    56701 tgattcctca gactcacttg gaaaaaattt atcgacaaag caaagaatca accatcgtca
    56761 ccctagctag tcagattcga cagggcatct tgccagctga tttcacccaa aaaaaagctg
    56821 accgttccta ctttgaaatt gctagtggcc atattcctgc caccattgaa aaaatcttag
    56881 gtgccgccct cagaaatggt attcctgccc gtgatatcca agttctggct cctatgtacc
    56941 gagggacggc agggattgat gctatcaatc agctcatgca agacctgctc aatcccccac
    57001 aaaaagatca actcagtttt gaagctcctc agtgccacta tcgtaaggga gacaaggtca
    57061 ttcatttggt taacgatgct gaaatcaatg tctttaatgg ggatttagga gctatcacag
    57121 acctgattcc tggtaaatac accgaatcga aacaagacga gattgtcatt gattttgatg
    57181 gtaatgaagt ctcttacccc cgtaacgaat ggtacaagat tcgcttggcc tatgccatga
    57241 gtattcataa gtctcaggga agtgagttcc cagttgtcat cctaccgatt actagtgcta
    57301 gccgacgtat gctggagcga aatctcatct acacagccat tacacgtgcc aaaagcaaac
    57361 tcatcttact aggcgaatta caagccttcg actatgctac ccaacacatc ggaactgccc
    57421 gaaaaaccta tctgattgaa cgcttcagtg atctactgga gaatgttgaa gaaaagcaac
    57481 aagctgtctc tgaaacagtc acatcaagtg cctctgaaca atcctacatc ctaaccgaag
    57541 aaaactggga cagcattcca gccatgattg ggattacaga cacagacctc aaagagattt
    57601 ttggaaaata gtgcatcaga aaaaccacca attcaggtgg gttttctgtt tattaagatt
    57661 attttactgt tgctgtgctt gtaatcaatt caacagcttt tttgatagtg atatcatgtt
    57721 tcaacatgtc agctgaaagc aagttttgaa cttgtgcaac ttccatgttg tagtctgctg
    57781 ccaattgctc aacttctttt tggatttctt cttctgaagc atcaaatcct tcagctttgg
    57841 caactgcttc gataacaagg ttagtcttag tacgtgactc agcttctgct tggtattggt
    57901 tgtgaaggtc ttcttgagta gttccagtaa tttggaagta catgtcaggg ttgatccctt
    57961 gacgttgcaa gttcccaagg aattcattta ctgaacggtg aacttcttcg tggatcattt
    58021 cttctggaag ttctacgatt tcagcatttt ctacagctgt atcaattgct gcaccttcaa
    58081 ctgcatcttt gtaagcttct tctttagcag cagccaattc tttgcggtat ttttctttca
    58141 agtcagcaag tgtttcaact tcttcatcaa tgtcttttgc aagttcatcg tcaagagctg
    58201 gaacttcttt agcttttact tcgtggatag ttgtcacgaa tttagcttct ttacctgcaa
    58261 ggtcttctgc ttggtagtct tctgggaatg ttacgataac atcaacggtt tcgccagctg
    58321 agtgacctac caattggtct tcgaaaccag ggatgaattg acctgaacca agtccaagtg
    58381 agaagttttc accttttcca ccgtcaaatt caacaccgtc gatagaacca acgaagtcga
    58441 tcacaacagt gtcgccgtct tcagcagcag cttccttgat aaccaattca gccaggttgt
    58501 tgcgttcacg ttcgatacgc tcttcgacat cagcgtcagt tacttctttt tctacatcaa
    58561 ctgatacttc aaggtttttg tagtcaccca attttacttc aggttttgta acaacttcag
    58621 cagcgataac ccagtcttga cctttttcca ttgaagttac gtcaattttt ggttgggcaa
    58681 ccacttcaag accagcctct tttacagctg cttcataagc gtttggcaaa agagcgttca
    58741 taacgtcttg gtaaagtgat tcttcaccaa attttttatc gaagatagga cgtggaaggt
    58801 gacctttacg gaaacctgga acattaagag atttcttcac tgacttgaag acacggtcca
    58861 attctggttt gatttggtct tgagagatag tgaaagtcaa gacaccacgg tttgtttctt
    58921 tgttttcaaa tgatacagac attctgtcat ttctccttaa aattttttaa atacagtcta
    58981 ttataacatt ttctataaat aaaatctaga ctaatgcaga caattataga caacaagcct
    59041 ttttcctaac taaaacactc ataaagtata gacaatttta gactactttg gatatctttt
    59101 ggttagtcat tttccaaaac taatttatct aatttttaag ttatatttga cttcatcttc
    59161 tcagtaacat gagtataaac acttaaaatc tttgtttcat tagtataatc tacacgatcc
    59221 attatcgctg ttataggtac ttccaattca gcaagcaaac ttatatgcga atatctaaaa
    59281 acatgagcag tcaatacaaa atcatctttc ttaatttcac ttttcctaaa cctgtttttc
    59341 aaaaagtaat tgaaacaagt tatcattaag ggagaaccat tatttgtaaa tatataatca
    59401 ccttcttcta aaagaagata ttcttttaaa atttctaaca ctctatcact aataccaatt
    59461 actctatatg aagctaaact tttcggacta tccaaaaaca cttcgttatt ggacgattac
    59521 attatagtaa aacgaaataa gaacaggaca aatcgatcag gacagtcaaa tcaatttcta
    59581 acaatgtttt agaagtagag gtgtactatt atagtttcaa tctactatac aagacgaaat
    59641 tgaagaaatc tttccattat aaaacgcata ttatcaaggt ttttaaacac ctaataatat
    59701 gcgttttttc ctattttaaa gacttttatc cacctattat acaaagttaa gtatccatca
    59761 cagtttacaa ttagccttca ttacctaacc cattcaccat ccttcaagag agtaaccttt
    59821 aagaaccgaa taaataaatg gcaaatttcg ttcatttaat ttaactgcac tgttaatttg
    59881 attagctcca tctcctaaag tatgcactcc tactacacgg tgactagcat cataaactgt
    59941 agatccacta gacccctcta aagtatcaac ttggtaatcc aagaacatgc catcatcact
    60001 taaaacttgt tttttatctg tatacatttg atgaacttta aaattatatg atggatagcc
    60061 tgtgatagtc acagttattc ctgtcaaatt tttttgacta gtaggaagac ccaaagtccc
    60121 taattttgca ccaatgggct cttctagaat taataaagcc aagtcatatt cccttgcatc
    60181 cttagaattt aaatttctaa attccttcaa ataacgaact tcctttactt tgatctttcc
    60241 aaatggttct tgacttggac taacagtcgg aagaacataa atatcatccg cttctttccc
    60301 atagtcatgt ctgtagtagt tgtgagccgc tgtaattaac acattatctt taataaaatt
    60361 cgcacttccc ctcccttcta cattcattcc atcggctact ccataatact tagataaaac
    60421 catagctgaa gtcgaatacg gatactgtaa agtattatca attttaatca aatcatcatt
    60481 accgataata cttctgattg cttttggtag tatgaaccat atgttggtga aatctcagat
    60541 aatgaagaat cattagatcc tggacctttt tctagtgtct cacttacctc atattcttca
    60601 cccgtactag aaataacact caaagcagat actgtcgata actggctagc caataaagta
    60661 ctcgcaataa ttgaaatacc caatttttta taaacagttt tcttcattat tgtatcctcc
    60721 taatgtaatt atagcgtact attctaaatt tcttaatcta ctatagaatc aagaaatcta
    60781 ccaccttctt taaataccct ccattatcac ataaacaggt aaacttttca attaatgact
    60841 gcgcttttca atcacgctag aggtacttac ttgcttcttt gatactaagt tcagccattc
    60901 tttccttgtt tttctcaata aagcatgtta cccaagtggg attcgttttg gagtagtctc
    60961 gcagagtcca gccaatggct ttattgataa aaaattctgt ttggttcaag ttatgaagta
    61021 gaatcttttc cattaattga gtattggtct tctcttttct taacaactgg tggtcaatag
    61081 cgacacgtct cagccagata ttatctgata ggctccattt tatactcaat gaaaatcaaa
    61141 gagcaaacta ggaagctatc tgcaacctca aaacactgtt ttgaggttgc agatagagct
    61201 gacgtggttt gaagagattt tcgaagagta ttaagattat ttcttctagt tcagggtgtt
    61261 catacaccaa actccctact actcgatcta ggatatctac cgtgtcccac caggattttg
    61321 tcacgactaa ctgctctagc ttaggcaaat cggtttcctt tagataagac tgcattgctt
    61381 tcaaatagtt agcagccaca tattggtatt ttctaggctc cttttcccag caagtgtctg
    61441 caaaatccca atcgataatc tttgtttttt tcgcttctgg taaatatttt tatagagttt
    61501 atttctttca ggcaccgcaa tacctagaaa agaaaattga tggcgcatat aggcttccat
    61561 gggccttgct tttttagagt cttttgctgc ttctagctcc tcaagtaaat ctgctaaact
    61621 catctaaaac tcctcttgcc ccaccaaatg gtgctgaaag gcatagacag ccgcctgggt
    61681 acgatcgctg acttcaagtt tggcaagaat attggacacg tgggtcttga ccgtcttgag
    61741 agagataaag aggtcatctg cgatgcgctg attttcgtag cccttggcga tgagttggag
    61801 aacatctcgc tcacgcgcag tcaattcttc atgaagttcc atatgattgc ggtggtattc
    61861 aaccttcttg ctaacctctt gctcaatggc cagctcgcca gcagctacct tactgacggc
    61921 atgaagcaat tcatctgcac tagaagtctt gagcatatag cctttggcac cagcatctaa
    61981 gactggcatg attttttcat tgtccaaata agaggtcaca atcaaaatct tggcttcagg
    62041 ccattcttta aggattgcta aggtcgcgtc aatcccattc atctcaggca tgacaatatc
    62101 catgacaatg acatctggac gcagttccaa ggccaagtca atcccttgag acccgttgga
    62161 cgcctcaccc acaacttcta catcgtcttg gaggtcaaag tagcttttca agcccaaacg
    62221 gaccatttca tggtcatcta ctagtaaaat tttcatcttt actcctttat cattccttat
    62281 ctaacagggg aatacggata tcaactgcca gcccttgctt gggagctgtt aataactgaa
    62341 ccgtccctgc catatcttca acccgctcct tgatatttcg cagtccataa ctcaagtcgt
    62401 ctaagcttcc taaccggaaa ccaatcccat tgtccaccac cttcagttgc aattcaacat
    62461 ctgtctgata gaggtagaca tctaggcaag atgcctgggc atggcggagg gtattgctaa
    62521 tcaactcttg caggatacgg aagatatgct cctcgatttt cttaggcaat ttcgtcatat
    62581 tctgcttgag actaacccta agatcactct tgtcctcaag ctcttttaag agaatctgaa
    62641 tcccttctat caagctcttc tgctccagtt caactggtcg caaatgcaag agcaaaaccc
    62701 gcaaatcctt ctgggcagtt tctaaaatag ctgtgacact ctgcaactgg gtctgcatct
    62761 tttctctatc caatttcaaa gcctgctgac tgatacccga taaaataatg tgggccgcaa
    62821 acaactcctg actgactgta tcgtgcaaat cccgagcaat tcgcttccgt tccttctcga
    62881 taatttcctc ttcctgatca aggctatgat tttcagcttt ttgaagagcc tctgtcaaaa
    62941 ggttaagttt acctgataag gacttgaaac tggcatccaa atctggatct acaacctgaa
    63001 ctacttcttg ccctgccaat aaacgcttga gattagcctg catttttctt agagaaagct
    63061 cttcgatccc tcgccaaaac agggctaaga gacaggtcat ggacatgctg aaaaccaaca
    63121 ataaaaagac aaatttttct gttttttcga catcgtacaa aaagatagac cagtcaaaat
    63181 caagtatttc cagcaagctg tgggagaaaa aaaagacaaa taggaaggag gtgagagcaa
    63241 taatgacata ggcttgtttt ttcatcctct aaccacctcc acatcaccaa tcatagtggt
    63301 caagaaaatc ttgacactct tgttactctt gagatagttt tttgtttctt gatgatagtg
    63361 ttcattgcgg agggctcgct tgggctggtt gaaaaaagtc aaatccccat agagacagtt
    63421 aacgctgaga ctgacttcca catctacagg tacgatgatt ttggtcgttc ctaccatctt
    63481 tctgaggata atgacattgt catgattggt taagatgacc ctctccagat gaatagtgtc
    63541 cttgcccatg aagcgaaaga gattgatatc atcgaattgg caagtctggt agcttgaaaa
    63601 atgatgaaga tttccaaacc aacgattttt ctccttctta accgtcacaa cctcttcaaa
    63661 aaccaaattg gtctgctctt tttcctggtt catcatcggg taaagaagaa agaggctata
    63721 gataaccgca acaaaaatag ctagaatcac aaaaggattg agcataacga tgaaaaagaa
    63781 gagaatggtt accgctacta aaagaagatt atttccctct ttaccagtgt agtagcgaat
    63841 caaaagcaaa aagaggaata gtatcagcag aaaacgcgaa aaatgctctg ataccatcaa
    63901 aatcagagct cctgtcagaa gacaggcttc gataaataaa aagattttaa attttctcat
    63961 aggttcatcc tctcccttct attttatcac aattcaaaaa agtcacctca gtctgaggat
    64021 ggaaaaaaag gcgctggtta cgcctttttc atctgatcat ttgcttcttt taattttcca
    64081 taaagaagat agtctacttt ttgtagatct gctatggtgg cacagttaag ggaacacata
    64141 atcaagcgta gatctgcttt ccagccttgg acaatgccaa gcacttcttc aactgtgtag
    64201 gtttcaacca attccagaac ggttcgtgac aatcccacag ccttagcacc aaaaaccaag
    64261 cacttaatca tatccagcgg attccgaacc cctccactaa ccaagagttc gaccttatct
    64321 ttccattctt gggcattgag aagggcctgc atggtagact gaccccattg attgaggtaa
    64381 tcacgctggc cactacgacg gttttcgata taggcaaagc tggtgccacc acgacccgat
    64441 aggtccactg tacgaacacc gaattcatag gctctttcga ttgtcttggc atccattcca
    64501 aagcccactt ccttgaggac aataggaacg ggaatttgct tgctataatc tgctagatgc
    64561 gattgccagc ttctaaactt cctttctccc tcgggcatga gtaattcctg catgacattg
    64621 acatgcactt gcaatagaac aggattcatc tcttctacag tatgaagtcc taactcgaca
    64681 ggcttgtcca atccaatatt ggttccaagg aggagattgg gatgactaga cttgacagaa
    64741 aaagaatcat ccgttggatt tttgagggct gcgctataag aacccgttac aaataaaata
    64801 ccacaggatt ccgccacctg agccagcttt tgattgattt ctcttccctt attacttcca
    64861 ccagtcatgg cattgatata aaaaggaaag tcccactttc gaccagcaaa ctctgtcgaa
    64921 agatcgattt catccagatt gtaaagaggc aaggaagaat gaatcagctc cacctcatca
    64981 aagctattat aggaactttt ctgctcaagg gcatagagga tatgctcgtc cttacgattt
    65041 gtcgtcatgt cctatccttt cttgatataa gagctcaatc cccagatcgg cccaacgatt
    65101 ttttaaggtt ttggttgatt gcgcatcaaa actcagggcg atgccacagt caccaccacc
    65161 agcaccacta ctcttggcaa cggcctgcaa atcttgactg gcttctttca actgtctaag
    65221 caaaggcgtg taaatatctg tactcaagcc ttctaaaagc ttgctggcta cttctacttg
    65281 ctcgataact ttttcggctt tcccctgctc caaggcttcg accaaagaaa ccaccgtttc
    65341 ttttgaggaa cttaaaaaat tttgattgat attttgcttg atttgctgga ccatgtgact
    65401 cgatacagcc acttccttgg tccatcccac taagaaatca cattctaaag ttggtttcac
    65461 ttgtgagata aaaaatcccc aatcacgctc cagaactgtc gccaagtttt cttcttctaa
    65521 ccaagcagcc gccttctggc gatcaaatga ctggtagaga accaaatcct ctgccacaat
    65581 acaggcaagg tcgcccatgg aaccattgtc tcctcgcttg agcaagacag cgctagtcag
    65641 cttgaacaag agattctgat caaccgaaag attatagaga gccagtaaag ccttgacaac
    65701 caagacaacg acgctgccac tagaacctag accaaacttt ttcccttctc gttccatttt
    65761 gccacagatt tttagggaaa aaggtcttaa attctgaccg cgaacagcga ggaagtctcc
    65821 catcaaagca atcgtttctt gaatcaagct gtagtcagga ttaggcctta agtccactgc
    65881 gaaatcaaac atatctgaat agatacggta gctgtcagaa aaagcaatct cagctctcat
    65941 atagatggga atatccttta tcaaagctaa ctgccctggc tctaaaatag catattcacc
    66001 tgcccaatag agttttccgc aagttttaac agcaatcatc ttgactcaaa tcctttgttt
    66061 ttgacacaat caagcgataa cgatgaccga aaatttctga taaatgctcc aagtctttct
    66121 cctgacagaa gaccttaaca ttgggaccag catccatggt aaagtagcag gcctctcctt
    66181 tctcacgaag ctggcgaaca aagtccatag cctcataaga ggcatccgtc agataagaaa
    66241 aggctggact agcagtcttt gtcgtagcat gcatagccag ggcatttttc tccgttaatt
    66301 ctccaatctt ggcaaaatca ttttccttga gataaatcag catatcctga tagtccttct
    66361 cagactgacg aacccagtcg tcgaaagtcg tcgaggtttc cacacaaagt ttcatcccgt
    66421 cacggctaga gattggtttt ttcttgtcct ctagcaccaa cataatcata gctagtttca
    66481 agtctgtctc tacagggtaa atttctccac tatccttatc ccaggctcct agtggtccat
    66541 aaaaactccg agaagaagag cctgaggcaa acttggcttc ctgcgctaac tgacttctat
    66601 ccaatccaag cttgaaataa gcattacaag ccttgaccag ggcggacaaa ccactagaac
    66661 ttgaggacag gcccgctgcc gtaggcatat tgttttgagt atcgatacgg acaaagccct
    66721 caccagctgg acgataacgg tcaataatct tactcatctt ggcatgctcg acctcatttt
    66781 gtagctgacc attgatgtaa aattcgtcag ctgttacatt ggctggtaaa ggcgacaagg
    66841 tcgtctctgt atacatattt tccaaagtta gagaaatact gctagtagca ggcaccatct
    66901 ctttttcttt tttctttccc caatatttaa taatagcaat atttgcgtag gaacgtactg
    66961 ttacaggctc tctatccatg tctgaacagc tcctttctct tctaatcttt ctgctagttc
    67021 ttgtgcgtgt gtcaaattgg ttaccaaggc tatgatacaa cctcctagcc caccaccgct
    67081 catcttggca cccagagcac catggctaag agtcgtttca accaaaaagt ctgcctcagg
    67141 gctactgact ccaatttctt ttaaatgtaa atgcgcttga ctgaggattt gtcccagtcc
    67201 ttcagcatct ttttgtgaaa ttgcaacttc tgcttgctgg gttaattctc ccaaggcatg
    67261 caaaaacggt agggcatcct tgcccttatt ttgaaccact tggatggctt cacgagtatg
    67321 accataaaca cccgtatcgg caatcaccaa ataggcggat aaatccatct caagttctgt
    67381 aaatcctacg ttcttgataa agcgaatagg ttggtcactg agacaggtct tagcatccaa
    67441 accactagga ttcatatggg caatcatttc agctcgattg accaagattt ctagtacatc
    67501 atgaggcaga tcagcctgat agtagtcaaa taccgcacga atggccgcta tgctgatagc
    67561 cgctgacgaa cccatccccc gtttctcagg gatagccgag tcaatctcac aacgaatgca
    67621 ggcttctgtg atatccaaat actccagtga ggcataaacc gccatggaca aggtatcctc
    67681 ctcataaagg cgccaaggac tctctgcagg aactacctta caggtcacct ccacctccaa
    67741 aagaggcagg gaaatggcag gataaccgta aacgaccgca tgttccccta ttaaaattat
    67801 cttactatgt gcctgaccga caccaacttt ttttgtcatt ttttcctttt actagacgaa
    67861 aaaacgtctt atttttcata caagtattaa ttctttccta tctattttat tatattttca
    67921 caaaaaaagc gattgtttcc attcacaatc gcttctttca ttattgaacc cattcgccat
    67981 tatagttgac agaatagcca tctacggtcg tattcactgc caaggcacct gagctataag
    68041 catagtacca tttgccattg acctggaacc aacctgtctt catgtctcca ttacctgcat
    68101 ttaggtagta ccaagttaaa ccatcttgat accagccagt taccatagct cctgatgaac
    68161 ggaggtagta ccacttgtta ccaaggtatt gccatcctgt tttcatatca ccatttttat
    68221 tatctaagta ataccatttg cctcgtacat atttccaacc tgttgccata gaaccagagg
    68281 agccaaaata ataccatttt ccgtttactt tttgccaatc tgtaagcatc ttacctgaag
    68341 catctaggta gtaccatgga gcaggtttgc ttctatcaat gtcaatagta acatgaaaat
    68401 cttgagtcca acccttagca acttcaccaa ttggtagtgg attgtaagaa tcatcgccaa
    68461 aatttcctag cttatttaaa taataccaat tgccgtcttc ataaatccag cctgtcttta
    68521 cagcataatt attatcaaaa taataagttc tcttttcagc agatagagga tattgttcac
    68581 cgtatacttt tcctgtattt tcagacgttt ttgcctctag tacttgttta tctgtttgtt
    68641 ctagcaaagc accatcttgt ccaaaatagt accacttctc ctgaaggcca atctcattaa
    68701 ctggttggtt atcgaataaa ttatcacgat aacctgttcc aggaatttct aagtattgcc
    68761 aaccgacaac catctctcca atatcaccaa aatagtaagt tttaccgtct attttatgcc
    68821 aatagattgc tttatgatca tcttttacat aatattttct attatcctta tcaacaaatc
    68881 ggccacctgt ggtattcgca aataccgtat ttgtagctag caaaccaaag aaaaagactg
    68941 ctagtagaac ttgcatcatt tttttcaaaa gtttcatcta tatatcctcc taaaacgatt
    69001 gtagcaaaga cccgactgca tgtcaatata taaaaactcc tcaaaaaagc agttacacaa
    69061 ctgcaactgc ttatctattc ttgcatggta tatccaacac cacgcacggt tttaatgtag
    69121 cttttttggc ctttaacatc aagcttgctc cgtagatagc ggatatagac atctacgata
    69181 tttgtctcgg tcgcactttc atacttccaa acactttcca acaattgctc acgagtcaat
    69241 actttcttgc ttcccataag tgtcgccaaa aggtcatact cacggcgggt cagagcaatc
    69301 atctcttcac cacgataaac cgtgtgatgt tcaacatcta tcctaagatt gcggtaggtc
    69361 cttggaactt tcatcagact gcagtgttga tcaatgaagt cccgacctcg gaagatcgcc
    69421 gaaatacgcg ctaccagatt ttcgataagg actggcttat aaatgtatga aactgcaaaa
    69481 cgctgaacaa cttccagctc ttcttgcaag tcttcccaat gatctaaaat catgatgact
    69541 gaggcaggtt tagttcgact caatttttct gcaaaatcct gagccatcat atctcccaga
    69601 ttaacgttca ataacatcaa atcatagtct gtctgaagag ccatggagag ggctttttgc
    69661 ccctcctcta ccagatcaac ccgatactgc tctttctgga gttccaaact taaaaaatga
    69721 gctagatttc gttctttctc aagtaataaa atccgtttcc ccatggctga cctacttatt
    69781 tttcgtcata ccaagagtag tggaaggttc cttctttgtc tttacgttgg taagtgtgag
    69841 caccaaagta gtcacgttgt gcttggatca agttagctgg aaggtcagct gaacggtagc
    69901 tatcaaagta agtaatagct gctgagaaag ttggcactgg cacaccagct tgaaccgcaa
    69961 gagctacgat atcacgcact gcttgttgat acttagcagt aacatccaag aagtactcgt
    70021 ccaaaagaag gttggcaaga tctgcatcgc ggttgtaagc atctgtaatc ttttgcaaaa
    70081 aacgagaacg gatgatacag ccatcacgcc agatagatgc gatatctgca aatggcaagt
    70141 tccagttgtt ttctttagag gctacacgca attgagcaaa tccttgtgcg tatgaaatga
    70201 tttttgagaa gtaaagggct tgacggatct tttcaatcaa ttcagccttg tctccttcaa
    70261 agttgaaggc agctggtttt ggaagcacct tgctagcata tacacgttct tctttgtaag
    70321 ttgaaatgta gcgtgcaaac actgactcag taatcagtga caatggtaca ccaaggtcaa
    70381 gagatgattg gctagtccat ttaccagttc ccttgttacc tgcagcatca aggatgtagt
    70441 ctacgattgg tccatcttgg ccttcatcgt ctttacggct caagatatca gctgtgattt
    70501 cgatcaagta gctatccaat tcacccttgt tccactcagt aaagatttca gccatatcct
    70561 ctgcagaaag acctagcaag tgttgcatca agtcataact ttctgcgatc aattgcatat
    70621 caccgtactc gataccgttg tgaaccattt tcacatagtg accagctcca tcaggaccga
    70681 tataagtcac acatggtttg ccatcttctg gtgctttagc tgagatttct tcaagaacat
    70741 ccgcaaccaa ttcgtaggcc tctttttgtc caccaggcat gatagaagga ccttcaagag
    70801 cacctttttc accaccagaa actccagtac cgataaagtt gatacctgag tttgccaatt
    70861 cttcattacg acggatggta tctttgtaga aagtatttcc accgtcaatc aagatatcac
    70921 ctttgtcaag gtgtggaaga agggcttgga tagtagcatc tgtaccaggt ccagcttgaa
    70981 ccatcagcat gatacgacga ggtttttcga ttgagtttac aaaactttca acgtcatagc
    71041 ttggtacaaa attcttttca ggatggcaag caatcacatc ttccgttttt tctttactac
    71101 ggttgtagat agcaactgtg taaccacgtg attcaatatt aagggcaagg ttacgaccca
    71161 ttacggccat acctacgaca ccaaagttag cttttgtcat ttgacactcc tcttgtttca
    71221 tttgttttat tttatcattt ttacttttga aaagaaagaa ttttgtaacg actgcttagt
    71281 agtccaagtc atccgcatga ccagcgccat ttccgacaaa gtagcctgtc ttacagttaa
    71341 gggtaaagag ataggttcca tctggcttat agaggttgta ataaccattg ccgttaacga
    71401 tattgacacg ttcaaggata tattggtctc cagtgatata gccacgtgaa cgtgaagtcg
    71461 ctagaatttg ttccaagaca ccatccgcaa aatcccaggc agagttatta ctatcatcaa
    71521 tagcagactg attataggca acacgactgg cacttctttg aacagcaacc cctgcactcg
    71581 agagacccat attgacttca ctgcgactac ttctagtctc atttgaacta cttggttttg
    71641 gctcactagt cgtatttgaa cttgcttgac ttgaacttga gctgctagtt tgacttaaac
    71701 ttgagctaga agtacttgtt tgctggctct taccaagact gatagcctta tctagcactt
    71761 tatcaagctc cgtatttcca gttttaatat ctgtaaattt agcatccgat ttggctttgg
    71821 cattggtatc caacacacca tccacaatag ctgatttttc aaattgtgca ttgacatctt
    71881 gaatagcctt gatttgcgtt gctagactat catatttaga tttggcaagc gtatgttcac
    71941 gactaccttc cagcttatca agtaaagtct tgagttgatt cagtttatca aactggctat
    72001 ttttcaaagc cgttttattg ctatctgtgt aaaaggcgtc ataaagtgta ttaaaatcat
    72061 ccacatccga ttgattggct gtagttgatt gagaagtttc aatttccttg gtcgaacgag
    72121 ccacttgacg gtagacataa taagcactga cacaaataat tactgataca agcgccaaaa
    72181 cggtcaaaat aaagcctttt ttacttttct tttctgagtc ctcttgatcc agacgagaaa
    72241 ggttttgctc ctcttccact tcttcagtca tttctgttgg attttcatca tctagcaata
    72301 gaggatccaa gccttgctcc tcatcgtcca gaggcaaggg tagtaagatg tcttcagaag
    72361 atggaacttc ctccgaagaa gcttctgact tctctacagc ctcacgcatc tcttgaatta
    72421 aatcatccag actctgagtt tcaacgaact cctctttttt gtattgacga gtcgcaaact
    72481 tatccgcctc aatttcatct ctgtgttgct taacatactt gtccaaaatg gaatcctcag
    72541 gcaagactcc tgcttccact tcttcatttt tacgaatagc ttgaccaact gttagctctt
    72601 ttgcttcatc aaaatcaaat tgcggttctt gaccttcttt tttttgacga tttcgtcttt
    72661 ttttactcat gagtatcctt tctattttac ctcttgccgt ttgacacgct gaccaaaata
    72721 ttgatataga tccactttca aggttccgtt gtataactta cgcttcttat ctgcttggct
    72781 accatacttg ctttcaaaag cttcatcact agtcaggata aatttgctcc aagttttcag
    72841 cggtgcaaat acttgcccca tctcagcata gagcttggtc acccctgcat catctgacaa
    72901 acgttcacca taaggcggat tggaaatgat tactccattg attttatcgg aacgtaaatc
    72961 ctgcacgcgc atctgcttaa aagtaatgtc tcctgcaaca ccagctacct gagcattggc
    73021 cttagcaatt tccaccatgc gagcatcaat atcacagccc attatatcca gctcaagctc
    73081 acggtctact tttttagccg cttctgtgcg cacttcttga atcaagcgat cgctgatcca
    73141 gttccattcc tcaaatgcaa aagagcgacg aagacctggc gccatctttc tagcaatcat
    73201 aactgcctca atacagaaag tccccgaacc acaggtcgga tcaatcaaag gcttgtctgg
    73261 ataccagtta gaaagttgta aaatggctgc tgccatattt tccttgatag gagcgccacc
    73321 tttttcggta cgataaccac gtttaaagag gctagacccg gtcgtatcaa tcatgacagt
    73381 tgccacatct ttgagaatag agacctcaat cttaaactct gggccattct ccatcagagg
    73441 aaccccttct gggcgagcat agtgtttctg caatttcttg acaacagctt tcttagaaat
    73501 agcctgaaca ctgggctcat tgtgaagttt ggacttaaca catttagctt ttgaaatcgg
    73561 gaaccgagct ccaagtggta aataattttc ccaatccaaa gcgaaaactc cctgaaatag
    73621 ctcttcaaaa gtcttagctg ggaacgttcc tacgataatt ttgatacgat ctgctgcccg
    73681 aagccaaagg ttggtttcga taatagctct cacgtctcct tgaaaacgaa cacgtccatt
    73741 ttcaacctga caatcgtagc ccaactctcg cacttcacga ccaacgacag cctcaagccc
    73801 tgctgccaca gttgcaatta aattaaattc ttttttcatg ttacagtctt gcaagacctt
    73861 tctatatgtc cactttaaaa aatgaggttg agaaaatttc tcagccccaa cctatatgca
    73921 attttctata agccatgttt tgttccagaa gtgactagga ccacttcctt cgataatcat
    73981 ctgtctacca ctaacagctc tagctgatag cagtcagaat actacgttcg tttccgcgta
    74041 ctccatgccc cgaccaaaat ttgggttgct agcttgaggg gtttaccgcg ttccactctc
    74101 tctgtttcca gaaagactcc gtcactgtgg cactttcaag cctactctgg cctatccaag
    74161 gacttagcca tttcaactgc cgtaacgatt tctcgtccct aggcttatgg tttcgcctag
    74221 cacaaacact acaggcatca cagcctgtgc tagcatggac tttcctcatg agaagcaatt
    74281 ctcctcacgc gattatccaa aaattgcaca tctcaaataa ctacttaaaa atctgagtta
    74341 tctaaaattt gtttaccaaa aacttctttt tccaatctat tcaggcgttt caaaatatca
    74401 aaattcgtca tagaacttgt aattgccgct tcaaggggtt ctgcttgaac tggtgaaggt
    74461 ttcggtttac gagttaattc ttccttcaaa tccgcaattt cctgacgaag tgacttgacc
    74521 aaggcagcat aggtttcata gtccttgatg acatcgtcta aaaactcgtc aacttctact
    74581 ttattatagc cacggacttc acgtccaaac tcttgttcaa aaatatcttt cgctgaaaaa
    74641 ataatacttg ccatgtctct ctccattctc gcttgctagt attattatat aaaaaaaggc
    74701 aaacaaaaat caaggtcaaa gcttcaattt tcggaaaaat tttcagcaag ttcatttaat
    74761 tgatcaaatg ttaatctctt tataaaatag tcctcttgat ttttcatctt ttggtaaaaa
    74821 taagctagtt ttgtttcatt ttcttcatca taaaaaagat aggaactagt cgtgttttcc
    74881 agcaaaaatt gctgataatc tcttaactgc cccttgtgtt cataacgagg ataagcatat
    74941 ttgacaaagt ctacctgctt aaagcgactc agtttcatct gattgccttc attccaattt
    75001 tccccatggg tttcaaaagc aaaaatggtg gccaactgga aaccgtattc ggttttcatc
    75061 tcctgagcaa cctctaaaac ccaatattca aaacccaaac ttcctgtaaa cacaagccaa
    75121 gacaccccat ctgctgccat agcctctaaa tctttacgta tcgctttttt aatcaattta
    75181 agacgaggat ccttatcaga aaataaaccc aaatcaaaag cagaatagcc taaaaccaaa
    75241 gctgtagcca tttttaaccc tttctgtgca aattatggta taataaagtg atgttattgt
    75301 accaataagg agaattatgg tcaactatcc acataaagtt tcatcacaaa aaagacaaac
    75361 atctctttct caacccaaaa atttcgcaaa tcgaggaatg tcttttgaaa agatgatcaa
    75421 tgctaccaac gactactatt tgtctcaggg cttggctgtt atacataaga aaccaactcc
    75481 tattcaaatc gtacaagtgg actatccaca acgaagtcgt gccaagattg ttgaagccta
    75541 ttttcgacaa gcttcaacga cggactattc tggcgtttat aatggatatt acatcgactt
    75601 tgaagtcaag gaaacaaaac aaaaacgtgc gattccgatg aaaaattttc atccacatca
    75661 gattcagcat atggaacaag tccttgccca acaaggaatc tgctttgtcc ttcttcactt
    75721 ttcttctcag caagaaacct acttattgcc ggcattcgat ttgattcgct tctatcatca
    75781 agataaggga caaaaatcaa tgccacttga atatattcga gaatatggat atgaaatcaa
    75841 ggctggtgcc ttccctcaaa ttccttatct caatgttatc aaagaacatt tattaggtgg
    75901 taaaacaaga tgaacaaacc aacgattctg cgcctaatca agtatctgag cattagcttc
    75961 ttaagcttgg ttatcgcagc cattgtctta ggcggaggag tttttttcta ctacgttagc
    76021 aaggctccta gcctatccga gagtaaacta gttgcaacaa cttctagtaa aatctacgac
    76081 aataaaaatc aactcattgc tgacttgggt tctgaacgcc gcgtcaatgc ccaagctaat
    76141 gatattccca cagatttggt taaggcaatc gtttctatcg aagaccatcg cttcttcgac
    76201 cacaggggga ttgataccat ccgtatccta ggagctttct tgcgcaatct gcaaagcaat
    76261 tccctccaag gtggatcaac tctcacccaa cagttgatta agttgactta cttttcaact
    76321 tcgacttccg accagactat ttctcgtaag gctcaggaag cttggttagc gattcagtta
    76381 gaacaaaaag caaccaagca agaaatcttg acctactata taaataaggt ctacatgtct
    76441 aatgggaact atggaatgca gacagcagct caaaactact atggtaaaga cctcaataat
    76501 ttaagtttac ctcagttagc cttgctggct ggaatgcctc aggcaccaaa ccaatatgac
    76561 ccctattcac atccagaagc agcccaagac cgccgaaact tggtcttatc tgaaatgaaa
    76621 aatcaaggct acatctctgc tgaacagtat gagaaagcag tcaatacacc aattactgat
    76681 ggactacaaa gtctcaaatc agcaagtaat taccctgctt acatggataa ttacctcaag
    76741 gaagtcatca atcaagtgga agaagaaaca ggctataacc tgctcacaac tgggatggat
    76801 gtctacacaa atgtagacca agaagctcaa aaacatctgt gggatattta caatacagac
    76861 gaatacgttg cctatccaga cgatgaattg caagtcgctt ctaccattgt tgatgtttct
    76921 aacggtaaag tcattgccca gctaggagca cgccatcagt caagtaatgt ttctttcgga
    76981 attaaccaag cagtagaaac aaaccgcgac tggggatcaa ctatgaaacc gatcacagac
    77041 tatgctcctg ccttggagta cggtgtctac gattcaactg ctgctatcgt tcacgatgag
    77101 ccctataact accctgggac aaatacccct gtttataact gggatagggg ctactttggc
    77161 aacatcacct tgcaatacgc cctgcaacaa tcgcgaaacg tcccagccgt ggaaactcta
    77221 aacaaggtcg gactcaaccg cgccaagact ttcctaaatg gtctcggaat cgactaccca
    77281 agtattcact actcaaatgc catttcaagt aacacaaccg aatcagacaa aaaatatgga
    77341 gcaagtagtg aaaagatggc tgctgcttac gctgcctttg caaatggtgg aacttactat
    77401 aaaccaatgt atatccataa agtcgtcttt agtgatggga gtgaaaaaga gttctctaat
    77461 gtcggaactc gtgccatgaa ggaaacgaca gcctatatga tgaccgacat gatgaaaaca
    77521 gtcttgactt atggaactgg acgaaatgcc tatcttgctt ggctccctca ggctggtaaa
    77581 acaggaacct ctaactatac agacgaggaa attgaaaacc acatcaagac ctctcaattt
    77641 gtagcacctg atgaactatt tgctggctat acgcgtaaat attcaatggc tgtatggaca
    77701 ggctattcta accgtctgac accacttgta ggcaatggcc ttacggtcgc tgccaaagtt
    77761 taccgctcta tgatgaccta cctgtctgaa ggaagcaatc cagaggattg gaatatacca
    77821 gaggggctct acagaaatgg agaattcgta tttaaaaatg gtgctcgttc tacgtggaac
    77881 tcacctgctc cacaacaacc cccatcaact gaaagttcaa gctcatcatc agatagttca
    77941 acttcacagt ctagctcaac cactccaagc acaaataata gtacgactac caatcctaac
    78001 aataatacgc aacaatcaaa tacaacccct gatcaacaaa atcagaatcc tcaaccagca
    78061 caaccataac atttatcacc cagatttttc tgggtgattt tgtcatagca ctattgtatt
    78121 tatgtgctta acaaaagcct gagaagacat cttctcaggc tttttctgta ctataaacct
    78181 cattggaaaa gatagagact gcttccgtaa tcttgttaag aggttttact aaatactagt
    78241 ctttcttcgt ttttactaca aagagagcag atagggctag actaacactt gctaggaaga
    78301 gggctgtgtc agattgactc tcacctgttg ctggcaagat ttgttcaggt gtttctggtc
    78361 tagctatttc ttgcttataa tctggcgtct taccttgatt ggaaactaaa gagctaagtt
    78421 taaactcagg tttctctaca gttggagcat ctggtttcgt agcagaatct tttaattggt
    78481 tgagataatc tgcaaagtat tccaccattc tttccgtcaa gagatggtta tccgtcgcat
    78541 atttcatgct tgcctgaacg ctagctactt cctcttgatt gtctttgtct gttaatttct
    78601 gagctttagc caaagctgct tcatagcctg acaagtcaag aggtgtttct gctacctgtg
    78661 gacgagtaaa gatgagttcc gctgcagatt ggtatttatc gccaccatct ccgtaagtct
    78721 tagtacctgt aaggacaatt ttcttagcct taattgtctt accaaaatca atgtcttttg
    78781 gcttattgtt atctggccaa tcagttgcag taaaggtatg ctccttgcca gactcatctg
    78841 tcacaacaag tttcacatca cgcaagttac catttgaacc tgatccacgt ggaacataac
    78901 gaagtccagt gatttcagtt ggttctttca agaccatggt tgcaggcttg cctacatctc
    78961 ctccgcccca tgatgtatgc cataaactag ataagtttcc atcaaaggca tttgcaagac
    79021 cttcttgagc ctgagcagga gctgtaagac tttcaaagtc ttctgctacc aaagccgttt
    79081 tcttctgaac caaagcattc ttcaaggctt caatcttggc aatctctgca cgcgcttctt
    79141 ccacactgat atcatcatcg gcctgactga ggttaaagac cgcctctttc aaagcatcca
    79201 tagactcttt ggtgtagtta gtcatggcaa ccgttggcaa gtagttcttc agagcatttt
    79261 ctgtcaacat cttacctgtt agggtaattt cttcgatttg aagattatcc atcatgaagt
    79321 cgttataacc acggaagttg gcatttccac cagaatcacc acgagtatta cttgcatttc
    79381 cagttgagta gatacctacc caagtatccc ctgtttctgc acctgtcaca aggaaggttg
    79441 ccttcttggc tttcttagaa tctgtccaag tatttggcaa ttcatgaatt tccaagttgc
    79501 ttgcttgagt gccacgacga cctgactgga attctccctt accgactaca aaagaatagg
    79561 tattgtctga acctgcttcg tattcaaagg ttacacggta ggtcttacct gcttcaaaac
    79621 ggaagttttg cggaatagtt tggtaaacca agttacgacg gctcactagt ccatttgtct
    79681 tgagtgacca atttccttcg ataacatcat cgactttttt accattccaa ccacgttgtg
    79741 tatatggatc gtgtttttca gacaagtgag tacggttgtc ttcgacacct tcgacaccac
    79801 ccactacaaa tgggaagata ccctgagcaa cattttcaaa gtcttgcttg aaggtgcctt
    79861 tacctgtatc atgcttgtct ccatacatgc ttgaattgtt ttcaaaggta cgaatttcat
    79921 caaagtaagt tgcttgatca ccagcttcac gactcaatgt cagagtaaca tttgagacgt
    79981 ccgatcctgt tgtaaagaag gcgtacatgt tttggaagta acttgtatcg ttaactgtag
    80041 cattgttacg acgtgtattg tgggcgtagg cttttacata gttgagggcg agagacttat
    80101 tggtataagt agtcacttct ttttcaccag tattcacagt gatacttgcc ttggcattac
    80161 tacggttatc tacaccaaca taaacggcat acttggtatt tggtttcaag ccagttaatt
    80221 tctgagtgag actaactttt tctttgtttc cttgaatacg aagcatatcg tttgcccctt
    80281 gagacttgac aatttctgcc ttagaagcat cgcctgaaat ggtccaatgt ttcaaggtac
    80341 cgctattaaa tccttggtca tagatgtgca tgccttcact ccatgacatt tcaggattag
    80401 tttgtttcga acgatagaga acgtatggtt gatttgctag aagatctagg gtaattttac
    80461 catcttttac agttagttct tgctcttctg tcttaccttg gtcagttagc ttgtaaaggt
    80521 aaaccttgct ctttgcccaa tcgcttggaa gggtccaagt tgttgcaccg gcctgcgtat
    80581 tgaagtagta catcttttcc ttatcagtag aaagtttctt accatttgca tcccagttcc
    80641 aaggagtcaa gtaagctgaa ccatcttgga tgacacgtcc gttgagcgtt actgtacgtt
    80701 cacggtatag tgggctattg acatcatttg acttacgagt tacaactaat ttattattgt
    80761 cagcatctac caactccact cgcatttctg gagtccattt ataagtgcta ccgttatcgg
    80821 tcatagtcac cggtgtacca ttttcccatt tacttacagt gaagtgttgg aagtacttgg
    80881 tcatgacgtc atgagcaaat aagttggtta catagccatt gtagtcactt cttccttgcc
    80941 agccttcaaa gtctttcatg ctgtagccac ctagcagtgg atagttggct gcaccaccat
    81001 aacttctgta gtccccaacc caagcatctt tttggtggtt acggataaag cgggtgatgg
    81061 cactgttgat acctttattg gtgtagccac cgtaggtcaa gtcagctgcc cagtgatgga
    81121 aggtagagtc gtactcacca ccatggcccc actcgatcgc aaagcgccag ccttgtttgt
    81181 taatttcttt agcaagaacg tgggtagccc aggcaccgtt atcacctgat tgaccattac
    81241 cccaaacgtc cacatagata aagtcgagac cgtcaccaag ttttttcttc aaatcttccc
    81301 aacgtgccaa acgactatga gctaggtcat aggcagcatc aatgttgata ccttgatcta
    81361 gccagttcca accatagcta tagcttccat ctggattctt acggagaatt ttttcattga
    81421 agtatttaga ctcaggataa gtttctgaag cgttaacgtg gatacctaga tgagctccat
    81481 atttcttagc cttctcaatt agggtcttga agtcttcgac accaccgata cgcttaccaa
    81541 tatcagcata gttcaagtga ccagagtcat ggccttcgct accatatcct ttaaggagaa
    81601 caccttgccc aagaccatct gtgtggagat tgattttctt gataccatcc aaggtcataa
    81661 ggaatggatt ttgtgcttga gaaccaaagt tcatcgcgat acggtaagct gtgatatcct
    81721 taactttttc ccaaccttga ggattgttca taatgctacg ataagcaatg gcaccatctt
    81781 gccaatcaac gttcttgtct gcattggcat cttcagtgat aacaacctta gcacttggaa
    81841 gttccttcgt gtattctggg aaaacaatgc ccttataagc tttttcccat tgccattcag
    81901 agctgtggat tcctacatag ttggcatttc cgactgtttc tttataagct gtcaaacgag
    81961 tccagtcatt cgaaccacca ccatagctat tttgagagtt actccaaaca ccagcagcaa
    82021 gcttatctgt agaaacaaat ccatacatgt aacccttggc taggtctttc attggattgg
    82081 ttacatcgat atgatcatct ccgctgacat gcgtattgtt tgacatggtt gccccatcaa
    82141 acttagctcc agtttgatca ctagaaacag agactaaagc attgccgagg aaactaatag
    82201 aagaaagtag ttttctttcg tcatcaatct tttgacctgg agtgacttga ttgtggttga
    82261 caatcttggt cacatcaaag tgcaattgat tgtccacaac ttgcaagcgt actgtcattt
    82321 ccgcattgat taagtgagca tcatcgcgaa gcttcatcaa gtactctgct gttgtctcat
    82381 tgattttctt ataagtgact tcaggggtga ttcggtggtt attgataaag acttggttga
    82441 actgttgcac ctgtcctggc aaagtatgcc cgttcaagct gtattccttg acacgaggga
    82501 aggcttggtc aatcactgct ttgaggacct tagactgaat cgtgtcataa gtcaccttgc
    82561 tatcatcaac ttcaggacct gtttcttttt cagcaggggt atcctctgtt tttaccccct
    82621 cttggttatc cgttttaatg ctgacaaccg tacgctcatc gtcataagag cccgccttga
    82681 gaaggatctt cttctcattt ttaagatggt cattgaccgc agctggtaga gtcactgtgt
    82741 caaagagatt gacatcgttg ttgctggcat ttagctgacc gtctgacttg agagtgatag
    82801 agagacggtt tgttgatcct gtttcaggag cagcaacacg actacctcta taccaagtgc
    82861 tagctgttgg agatttatac tcccagaacc agccatcctt gtcataaccg acaaaaacat
    82921 tattattggt atctttaaat ttcaagaaga caccaaagcg tgatttgccc ttttcagaat
    82981 catctttgaa ggttaaatca acagttgcat ttccattggc atcaacggtc aagcccttct
    83041 tttcaaacag agctggttta cctgcgttat cattttgagc agttgaggat agttggttgt
    83101 agcggacacc tttttcttct cggatagtga ctgttccctg ttgttctttt ttctctaccg
    83161 tttgccattc aggggttacc gtcttaggtg tttcaggttt agcagctgca ggtttatcct
    83221 cttttggttt ttcttcagcc ggtttttctt tttcaagtgc taatagttct tcttctgtct
    83281 taggtccatc tgtaacttct ggagaacctt ggtcttctcc caccttaggc gcttcaaaat
    83341 cacgcccatc attctctttt gctgttgcaa gagcagtagc taaatcagct ggtaagttcg
    83401 ccgtggaacc agactgcacg ctatctgcaa gaaccggact tgtcccaaag aatgcagctc
    83461 caatcataac agaagcaaca cctaatgaaa atttccgaat actatattta caacgttttt
    83521 caaataatcc tttattcata aacttctaaa tcctttcatt tttgagcaag cgtttacatt
    83581 ttctttttaa aaaatactcc ttcctctgaa agtgcaatgc ttaaccctga taaataaaaa
    83641 taattatact tttaatataa caaataataa ctgagaaagc aataggaaac aagtaaaatt
    83701 aacaaaaatt ttctctattc tgacaaaaag aggctccaac ttttgggggt cagtacattt
    83761 agaatctttc tttacaaatg taaaaaagga ttcagcattc aagagaaata ctaaatcctt
    83821 tcttatattt tgcaacagtt atttcacatg ttttgcgaga tcttcttgag cctttttatt
    83881 agactcttct ttttctttca tccatttttc ctgagctttt tggtattcat ctacagtgac
    83941 tgccttgtct tgaagttcca agtatttata caagactggt tcacttgtac ctttatttcc
    84001 tgacaatgca aatggtattg taaatggtat catcttagac aagattgggc gacctgtacg
    84061 agatgtagtt ggaataatca aagcactatc tgtcaaccaa gcttgggctg cagcgtattt
    84121 atcatagcgt ttagcaacat ctgtagcctc atcaccagcc tcagtgacca atttttcgta
    84181 gtcatataga tctacttttt tagcagctac attatcttcc cctgagtcaa accctaaata
    84241 tgttttagta ctttctccta cagaaggttt gataatatca aggtaggttg atggatcggc
    84301 aaagtctgga ccccaaccga cattatctga taaatcccag tcttcgccag cagcattttc
    84361 agcaaaatat gtaatattgt ttacttcgtc tttttgtagt tgttgaatat caataatgac
    84421 attatcagct cctaaagttg cttccaagga ttgtttcata gattggacgc gctgaacttt
    84481 tgtagttgct gtctggtcaa ctggcatatc caaatgaatt gggaaagtca caccttctgc
    84541 ttgtaaggct gatttagctt tagcaaattc agccttggct ttttctggat tgtaaagacc
    84601 atcctgagaa tctgcaagat taacatcctt ccattcatcc ccataagtga ccaatttctc
    84661 tttgaccata tcgccaaagt ttttaccatc tgcttgaaca aatgttggtg gaacaaagat
    84721 attacgtaag attttgcttg ctccagtttg tccattcaac tgagaggcat aggctgtacg
    84781 atcaaaacca aaggcaatag cctgacggaa atccttgttt aagagagcct ttttagtcga
    84841 tgccttttgt tcgtcgctgg tcttagatgt gtatttatag gactgacggt caatatttgt
    84901 accaactaga tacgtaatag agtcttgttg agtatagaca atattgtcct tcatactctt
    84961 ctcaagctct gcgaaacttg cacttgttgg atagagacga gctgctgtaa ggctaccatc
    85021 tttaaagttt tctgcaggtt tgctggtatc ttgaccatcc cagaatgaca atttaacttt
    85081 gtcaatatgc acattgtcct tatcccagta gttcggattt ttcgcaaatt caacagagga
    85141 tttggtcaca atggatttca acaaataagg accgttatac aagagactac ttggatccgt
    85201 agctttggca aaatcatctc cttttgaatt caaaaactct tcattaactg gcgcaagcac
    85261 acccatggtt gtcttagaat tccagaagct ttctggtttg ttcaaagtgt actgaactgt
    85321 ctgttcatcc agagccttaa ttcctacttg tgagaaatct ttgatttccc cttttacata
    85381 ggcatccaac cctttgattg attcttgaac aaggtaaaga gcatctgatt ttttatcagc
    85441 agcatatttt agtcctgtta caaagtcttg agctttgact gccgcgtatt cttcaccttc
    85501 agaagtatac cattttgcat ccttacggat agtataagtg taagtcaatc catccttgga
    85561 tacagaccaa tcctcagcca tagacggcac aaagttcccg tagcgatcat tttctagcaa
    85621 accatcaacc acgttactgg taatatttgc tgtcgcagcc ttagcagttg tcaaatagtt
    85681 gaggttatca gggtctgtct cataaatgta tgagaatgtc ttctcacctt tagcgcttga
    85741 acctgatcca gagcatgcag ctaaagtagt cgccgccaat aatgtcacgc ccgcaagggc
    85801 aaatagtttt gaacttttca tcattttctc ctttaaaact ttctctccat tatagactct
    85861 tttcaaaaag atgtcaacag aattttcaga atttttgggt tagtttagta tattctgaaa
    85921 agaccaaaaa ggagaagacg gtgattgtcc tctccagatg ttagctgaca aagagccaaa
    85981 ataatttatt ttaatttaat atacttctgt ggtaataaaa caatattcaa aaatggaatt
    86041 tttttcaata tataggttgc taggatggat aaatgccagc ccaaaacaat tccgataaca
    86101 atatgaagta aagtagagct aattcccact ttcaacatca gaattagaat catactacaa
    86161 attggggaat ggaggatata gacgctctac taaaactaaa aatattgaga acccttttcc
    86221 aaaatctatc caattgattc taatttttgt cattttcaaa ctctttttct ataacttcga
    86281 gcgctcgttc aatcacaaca tgcatatcgt aatatgtata atctgctaag cgtcccattg
    86341 cttctcagta tagaccgctt ctaacaatta attttttaca tttttattat actaaatcaa
    86401 tctctttcaa aaatatcacg tgtatagact ttttccttga catcttctaa tgagttatca
    86461 tagcgattag caacaatggc attactcagt cgtttgaatt cctctaaatc attgataatg
    86521 gaacttccaa aaaatgtact cccactttct aaagttggtt cataaataac tactcttact
    86581 cccttagctt ttatacgttt cataatacct tgaatagaac tttgacgaaa attatcgcta
    86641 ttactcttca tggtcaatct atagatacca ataataatat ctttttctac tctctcatta
    86701 aaaacattat gggctgaata atcataataa tctaccatct taagaacctg atcggcaata
    86761 aagtctttac gtgtcgaatt gctccgtact atagctccta taagttcttc tggtacatct
    86821 tcatagttgg caagaagttg cttggtatct ttagggagac agtaaccacc atacccgaag
    86881 gaaggattgt tatagtgaga gccgattcgt ggatccaaac caactccatc aataatagct
    86941 tgagtatcta gccccttcat ctcagaataa gtatccagct cattaaaata agaaacacgc
    87001 aaagctaggt aagtatttgc aaaaagcttg accgcctcag cttcagtaaa gcccatgtac
    87061 aatgtatcaa tatcttcttt taaagcgcct tcttggagca atcccgcaaa cgtctcagca
    87121 acacttacca agcgttcatt atttttatct gtccctaaaa taatacggct gggatataag
    87181 ttatcgtaaa gtgcttttga ctcacgcaaa aattcaggac taaataagat attttcagtc
    87241 tgaaatttct ttcgagctga ctctgtataa ccaactggaa ccgtactttt aatgaccatg
    87301 atagcatctg gattatattt aagcaccgtt tcaatgacag actctacagc agaagtgtca
    87361 aagaagttct tctttggatc atagttagtt ggagctgcaa tcacaacaaa atccgcatct
    87421 ttatatgctt cttttgcatc caatgtagcc actaaattta aatccttttc tgccagatat
    87481 ttctctatgt agtcatcttg aataggtgac tttctttgat taattaactc gaccttctca
    87541 ggaataatgt ccaccgctat tacttgatga tgctgagcca ataaaaccgc aatggatagg
    87601 ccaacatatc ccgtacctgt tactgctatt ttcatacttt ttcttccctc ctcatatatt
    87661 tgcctatcat tctacaaatt agaaaatata tagattcctt caattaatta ttctttaaca
    87721 ttattgtaga acatgtacta gtattagtaa aaagtatact taaaaataag aactggaatc
    87781 cataacttgg aaatattaaa tcagtttctg ttaccgcata catagaccaa gctaataata
    87841 aaatcaaact tttattgtct aaatattttt gtagttttac aaataagact gataagataa
    87901 gtagccatat gatgccagca ttactcatca agaaggaata aaacgaatca aaagtgaaac
    87961 tagttaatcc ccaaatagga tcccaaacaa tttctttatc aacatattga ccccagaatg
    88021 tataaccaaa aaaggttctt gcgtatgcag ctaatttaat acgtccagtc aggatattat
    88081 caataaaaat tgaaaactta ttattagaag gataaaattg aaatgccaaa actcctaaaa
    88141 aagtagaaat ac
//
LOCUS       DBJKQU010000003        80769 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.003, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000003 DBJKQU010000000
VERSION     DBJKQU010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 80769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80769
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.003"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(381..1361)
                     /locus_tag="ACSUUC_000193"
     CDS             complement(381..1361)
                     /locus_tag="ACSUUC_000193"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0045493 - xylan catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HHQ8053495.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1677..3692)
                     /gene="recG"
                     /locus_tag="ACSUUC_000194"
     CDS             complement(1677..3692)
                     /gene="recG"
                     /locus_tag="ACSUUC_000194"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HHQ8053496.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLNGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERETDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMIETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEVWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3711..4814)
                     /gene="alr"
                     /locus_tag="ACSUUC_000195"
     CDS             complement(3711..4814)
                     /gene="alr"
                     /locus_tag="ACSUUC_000195"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HHQ8053497.1"
                     /translation="MKASPHRPTKVLIHLGAIRQNIQQMGTHIPQGTLKWAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4804..5166)
                     /gene="acpS"
                     /locus_tag="ACSUUC_000196"
     CDS             complement(4804..5166)
                     /gene="acpS"
                     /locus_tag="ACSUUC_000196"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HHQ8053498.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            complement(5211..6242)
                     /locus_tag="ACSUUC_000197"
     CDS             complement(5211..6242)
                     /locus_tag="ACSUUC_000197"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HHQ8053499.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6244..7275)
                     /locus_tag="ACSUUC_000198"
     CDS             complement(6244..7275)
                     /locus_tag="ACSUUC_000198"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HHQ8053500.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7356..9869)
                     /gene="secA"
                     /locus_tag="ACSUUC_000199"
     CDS             complement(7356..9869)
                     /gene="secA"
                     /locus_tag="ACSUUC_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HHQ8053501.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKKRYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10063..10302)
                     /locus_tag="ACSUUC_000200"
     CDS             complement(10063..10302)
                     /locus_tag="ACSUUC_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053502.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLVFGILSILMALLSKKVSLFVFGLICCLSL"
     gene            complement(10330..10962)
                     /locus_tag="ACSUUC_000201"
     CDS             complement(10330..10962)
                     /locus_tag="ACSUUC_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHQ8053503.1"
                     /translation="MKLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10966..11607)
                     /locus_tag="ACSUUC_000202"
     CDS             complement(10966..11607)
                     /locus_tag="ACSUUC_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053504.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            complement(11600..12391)
                     /locus_tag="ACSUUC_000203"
     CDS             complement(11600..12391)
                     /locus_tag="ACSUUC_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053505.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12576..12911)
                     /locus_tag="ACSUUC_000204"
     CDS             complement(12576..12911)
                     /locus_tag="ACSUUC_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053506.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     SLFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVRH"
     gene            complement(13051..13386)
                     /locus_tag="ACSUUC_000205"
     CDS             complement(13051..13386)
                     /locus_tag="ACSUUC_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053507.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13477..14787)
                     /gene="der"
                     /locus_tag="ACSUUC_000206"
     CDS             complement(13477..14787)
                     /gene="der"
                     /locus_tag="ACSUUC_000206"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HHQ8053508.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14801..15514)
                     /locus_tag="ACSUUC_000207"
     CDS             complement(14801..15514)
                     /locus_tag="ACSUUC_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HHQ8053509.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15511..16407)
                     /gene="dnaI"
                     /locus_tag="ACSUUC_000208"
     CDS             complement(15511..16407)
                     /gene="dnaI"
                     /locus_tag="ACSUUC_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HHQ8053510.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16408..17577)
                     /locus_tag="ACSUUC_000209"
     CDS             complement(16408..17577)
                     /locus_tag="ACSUUC_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HHQ8053511.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRDR
                     GQKAKTQKQNQTAPEKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17578..18051)
                     /gene="nrdR"
                     /locus_tag="ACSUUC_000210"
     CDS             complement(17578..18051)
                     /gene="nrdR"
                     /locus_tag="ACSUUC_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HHQ8053512.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18191..18556
                     /locus_tag="ACSUUC_000211"
     CDS             18191..18556
                     /locus_tag="ACSUUC_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHQ8053513.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18561..19256
                     /locus_tag="ACSUUC_000212"
     CDS             18561..19256
                     /locus_tag="ACSUUC_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053514.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19273..20040
                     /locus_tag="ACSUUC_000213"
     CDS             19273..20040
                     /locus_tag="ACSUUC_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053515.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20393..21592)
                     /locus_tag="ACSUUC_000214"
     CDS             complement(20393..21592)
                     /locus_tag="ACSUUC_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8053516.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVEVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21589..22482)
                     /locus_tag="ACSUUC_000215"
     CDS             complement(21589..22482)
                     /locus_tag="ACSUUC_000215"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053517.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            23189..23377
                     /locus_tag="ACSUUC_000216"
                     /pseudo
     CDS             23189..23377
                     /locus_tag="ACSUUC_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23792..24409
                     /locus_tag="ACSUUC_000217"
     CDS             23792..24409
                     /locus_tag="ACSUUC_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HHQ8053518.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24729..25616)
                     /gene="scrK"
                     /locus_tag="ACSUUC_000218"
     CDS             complement(24729..25616)
                     /gene="scrK"
                     /locus_tag="ACSUUC_000218"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HHQ8053519.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25765..27702)
                     /locus_tag="ACSUUC_000219"
     CDS             complement(25765..27702)
                     /locus_tag="ACSUUC_000219"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HHQ8053520.1"
                     /translation="MDYSKVAAEVIEAVGKDNLVAAAHCATRLRLVLKDEAKVNQAAL
                     DNNADVKGTFSTNGQYQIIIGPGDVNFVYAEIIKKTGLKEVSTDDLKEIANKDKKFNP
                     LMDLIKLLSDIFVPIIPALVAGGLLMALRNFLTSPDLFGPQSIEDMYPAIKGFSAMIQ
                     LMSAAPFMFLPVLIGISAAKRFGANQFLGAAIGMIMTTPDLGGKEAFWDILGFHVTQT
                     NYAYQVIPVLVAVWLLANLEKFFHKKLPSAVDFTFTPLLSVMITGFLTFTVIGPVMLV
                     VSDAITNAIVWLYNTTGAFGMGLFGGTYSLIVMTGLHQSFPAIETQLLSAYNNNGTGF
                     GDYIFVVASMANVAQGAATLAVYFLTKNAKTKGLSSSAAVSAFLGITEPALFGVNLKY
                     KFPFFCALAGSAIGAFVAGLTHVIAVSLGAAGFIGFLSIKAGSIPMYIIAEIMSFVAA
                     FAFTYFYGKTKAASVFADEAATATAETVTEPTVEAPVVEETDTLQNETLVTPIVGDVV
                     ALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLI
                     HVGIDTVSMNGDGFEAKVAQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYA
                     SVAPVATGSVAKGNAVIEVKI"
     gene            28078..29532
                     /locus_tag="ACSUUC_000220"
     CDS             28078..29532
                     /locus_tag="ACSUUC_000220"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HHQ8053521.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQNLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29513..30478
                     /locus_tag="ACSUUC_000221"
     CDS             29513..30478
                     /locus_tag="ACSUUC_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHQ8053522.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30513..31787)
                     /locus_tag="ACSUUC_000222"
     CDS             complement(30513..31787)
                     /locus_tag="ACSUUC_000222"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HHQ8053523.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(31787..32959)
                     /locus_tag="ACSUUC_000223"
     CDS             complement(31787..32959)
                     /locus_tag="ACSUUC_000223"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HHQ8053524.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLNKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(33090..33338)
                     /locus_tag="ACSUUC_000224"
     CDS             complement(33090..33338)
                     /locus_tag="ACSUUC_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053525.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(33406..34031)
                     /locus_tag="ACSUUC_000225"
                     /pseudo
     CDS             complement(33406..34031)
                     /locus_tag="ACSUUC_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(34093..34542)
                     /locus_tag="ACSUUC_000226"
     CDS             complement(34093..34542)
                     /locus_tag="ACSUUC_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HHQ8053526.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(34544..35302)
                     /locus_tag="ACSUUC_000227"
     CDS             complement(34544..35302)
                     /locus_tag="ACSUUC_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HHQ8053527.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(35418..37397)
                     /gene="stkP"
                     /locus_tag="ACSUUC_000228"
     CDS             complement(35418..37397)
                     /gene="stkP"
                     /locus_tag="ACSUUC_000228"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HHQ8053528.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(37394..38134)
                     /locus_tag="ACSUUC_000229"
     CDS             complement(37394..38134)
                     /locus_tag="ACSUUC_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HHQ8053529.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(38149..39462)
                     /gene="rsmB"
                     /locus_tag="ACSUUC_000230"
     CDS             complement(38149..39462)
                     /gene="rsmB"
                     /locus_tag="ACSUUC_000230"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HHQ8053530.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFTNGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(39455..40390)
                     /gene="fmt"
                     /locus_tag="ACSUUC_000231"
     CDS             complement(39455..40390)
                     /gene="fmt"
                     /locus_tag="ACSUUC_000231"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HHQ8053531.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKSEEEKLNWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(40403..42799)
                     /locus_tag="ACSUUC_000232"
     CDS             complement(40403..42799)
                     /locus_tag="ACSUUC_000232"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HHQ8053532.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFDSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQMVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(42865..43179)
                     /gene="rpoZ"
                     /locus_tag="ACSUUC_000233"
     CDS             complement(42865..43179)
                     /gene="rpoZ"
                     /locus_tag="ACSUUC_000233"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HHQ8053533.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(43204..43830)
                     /gene="gmk"
                     /locus_tag="ACSUUC_000234"
     CDS             complement(43204..43830)
                     /gene="gmk"
                     /locus_tag="ACSUUC_000234"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HHQ8053534.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(43960..45573)
                     /locus_tag="ACSUUC_000235"
     CDS             complement(43960..45573)
                     /locus_tag="ACSUUC_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HHQ8053535.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAACPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(45764..46018)
                     /locus_tag="ACSUUC_000236"
     CDS             complement(45764..46018)
                     /locus_tag="ACSUUC_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HHQ8053536.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            complement(46022..46276)
                     /locus_tag="ACSUUC_000237"
     CDS             complement(46022..46276)
                     /locus_tag="ACSUUC_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HHQ8053537.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSIQVHVIEE"
     gene            complement(46514..47611)
                     /locus_tag="ACSUUC_000238"
     CDS             complement(46514..47611)
                     /locus_tag="ACSUUC_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HHQ8053538.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHTIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVEAVATKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETS"
     gene            complement(47621..48361)
                     /locus_tag="ACSUUC_000239"
     CDS             complement(47621..48361)
                     /locus_tag="ACSUUC_000239"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent DNA methyltransferase"
                     /protein_id="HHQ8053539.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(48470..48823)
                     /gene="rsfS"
                     /locus_tag="ACSUUC_000240"
     CDS             complement(48470..48823)
                     /gene="rsfS"
                     /locus_tag="ACSUUC_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HHQ8053540.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(48836..49336)
                     /locus_tag="ACSUUC_000241"
     CDS             complement(48836..49336)
                     /locus_tag="ACSUUC_000241"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HHQ8053541.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(49337..49930)
                     /gene="yqeK"
                     /locus_tag="ACSUUC_000242"
     CDS             complement(49337..49930)
                     /gene="yqeK"
                     /locus_tag="ACSUUC_000242"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HHQ8053542.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(49930..50559)
                     /locus_tag="ACSUUC_000243"
     CDS             complement(49930..50559)
                     /locus_tag="ACSUUC_000243"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HHQ8053543.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(50611..50922)
                     /gene="yhbY"
                     /locus_tag="ACSUUC_000244"
     CDS             complement(50611..50922)
                     /gene="yhbY"
                     /locus_tag="ACSUUC_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HHQ8053544.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(51137..52243)
                     /gene="yqeH"
                     /locus_tag="ACSUUC_000245"
     CDS             complement(51137..52243)
                     /gene="yqeH"
                     /locus_tag="ACSUUC_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HHQ8053545.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAYEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(52246..52773)
                     /locus_tag="ACSUUC_000246"
     CDS             complement(52246..52773)
                     /locus_tag="ACSUUC_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HHQ8053546.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            complement(52788..53696)
                     /locus_tag="ACSUUC_000247"
     CDS             complement(52788..53696)
                     /locus_tag="ACSUUC_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HHQ8053547.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(53753..54313)
                     /locus_tag="ACSUUC_000248"
     CDS             complement(53753..54313)
                     /locus_tag="ACSUUC_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HHQ8053548.1"
                     /translation="MQKFIQAYIEKLDVTSIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            54452..55670
                     /gene="sstT"
                     /locus_tag="ACSUUC_000249"
                     /pseudo
     CDS             54452..55670
                     /gene="sstT"
                     /locus_tag="ACSUUC_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            55738..56691
                     /locus_tag="ACSUUC_000250"
     CDS             55738..56691
                     /locus_tag="ACSUUC_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HHQ8053549.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEKIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYGQ"
     gene            56835..57215
                     /locus_tag="ACSUUC_000251"
     CDS             56835..57215
                     /locus_tag="ACSUUC_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HHQ8053550.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            57315..57536
                     /locus_tag="ACSUUC_000252"
     CDS             57315..57536
                     /locus_tag="ACSUUC_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HHQ8053551.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            57553..57867
                     /gene="trxA"
                     /locus_tag="ACSUUC_000253"
     CDS             57553..57867
                     /gene="trxA"
                     /locus_tag="ACSUUC_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HHQ8053552.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            58173..58706
                     /gene="queF"
                     /locus_tag="ACSUUC_000254"
     CDS             58173..58706
                     /gene="queF"
                     /locus_tag="ACSUUC_000254"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HHQ8053553.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKPLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(58916..59584)
                     /locus_tag="ACSUUC_000255"
     CDS             complement(58916..59584)
                     /locus_tag="ACSUUC_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HHQ8053554.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(59695..60486)
                     /locus_tag="ACSUUC_000256"
     CDS             complement(59695..60486)
                     /locus_tag="ACSUUC_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HHQ8053555.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLYADANQ
                     QSVFYQGLQLEIRNVFSNQGLHYLSKEKDTTGFSSQYGWIHSFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            complement(60911..61675)
                     /locus_tag="ACSUUC_000257"
     CDS             complement(60911..61675)
                     /locus_tag="ACSUUC_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8053556.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAILMTPIN
                     TSDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            complement(61668..62438)
                     /locus_tag="ACSUUC_000258"
     CDS             complement(61668..62438)
                     /locus_tag="ACSUUC_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053557.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
     gene            62687..63364
                     /locus_tag="ACSUUC_000259"
     CDS             62687..63364
                     /locus_tag="ACSUUC_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HHQ8053558.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            complement(63424..65220)
                     /gene="pepF"
                     /locus_tag="ACSUUC_000260"
     CDS             complement(63424..65220)
                     /gene="pepF"
                     /locus_tag="ACSUUC_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HHQ8053559.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFENFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(65231..65974)
                     /locus_tag="ACSUUC_000261"
     CDS             complement(65231..65974)
                     /locus_tag="ACSUUC_000261"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HHQ8053560.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(65976..66926)
                     /gene="prmA"
                     /locus_tag="ACSUUC_000262"
     CDS             complement(65976..66926)
                     /gene="prmA"
                     /locus_tag="ACSUUC_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HHQ8053561.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            complement(67062..67490)
                     /locus_tag="ACSUUC_000263"
     CDS             complement(67062..67490)
                     /locus_tag="ACSUUC_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHQ8053562.1"
                     /translation="MELEISDFTGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(67471..68559)
                     /locus_tag="ACSUUC_000264"
     CDS             complement(67471..68559)
                     /locus_tag="ACSUUC_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HHQ8053563.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAILFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENWLAELEKEMLEGTEDGTRNF"
     gene            complement(68578..69048)
                     /locus_tag="ACSUUC_000265"
     CDS             complement(68578..69048)
                     /locus_tag="ACSUUC_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HHQ8053564.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKIGLEKGEFYPYPKY"
     gene            complement(69339..69791)
                     /locus_tag="ACSUUC_000266"
     CDS             complement(69339..69791)
                     /locus_tag="ACSUUC_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HHQ8053565.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(69828..70007)
                     /locus_tag="ACSUUC_000267"
     CDS             complement(69828..70007)
                     /locus_tag="ACSUUC_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HHQ8053566.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            complement(70144..70323)
                     /locus_tag="ACSUUC_000268"
     CDS             complement(70144..70323)
                     /locus_tag="ACSUUC_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053567.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(70488..70709)
                     /locus_tag="ACSUUC_000269"
     CDS             complement(70488..70709)
                     /locus_tag="ACSUUC_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053568.1"
                     /translation="MEMMELPSQEILIFTKQIRHWILSDQVISGKRKLFFREDTPKEI
                     LDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            71001..72272
                     /locus_tag="ACSUUC_000270"
     CDS             71001..72272
                     /locus_tag="ACSUUC_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HHQ8053569.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            72537..72609
                     /locus_tag="ACSUUC_000271"
     tRNA            72537..72609
                     /locus_tag="ACSUUC_000271"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:72570..72572,aa:Lys,seq:ctt)
     gene            complement(72817..74136)
                     /locus_tag="ACSUUC_000272"
     CDS             complement(72817..74136)
                     /locus_tag="ACSUUC_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HHQ8053570.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(74146..75762)
                     /locus_tag="ACSUUC_000273"
     CDS             complement(74146..75762)
                     /locus_tag="ACSUUC_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHQ8053571.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKATDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTIPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSNYLAIKQKYYDQYQANKN"
     gene            complement(75791..76681)
                     /locus_tag="ACSUUC_000274"
     CDS             complement(75791..76681)
                     /locus_tag="ACSUUC_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHQ8053572.1"
                     /translation="MKNSIMDTKFNRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            complement(76692..77609)
                     /locus_tag="ACSUUC_000275"
     CDS             complement(76692..77609)
                     /locus_tag="ACSUUC_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8053573.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYDYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            complement(77759..78760)
                     /locus_tag="ACSUUC_000276"
     CDS             complement(77759..78760)
                     /locus_tag="ACSUUC_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHQ8053574.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            complement(79121..80602)
                     /gene="mgaSpn"
                     /locus_tag="ACSUUC_000277"
                     /gene_synonym="mgrA"
     CDS             complement(79121..80602)
                     /gene="mgaSpn"
                     /locus_tag="ACSUUC_000277"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HHQ8053575.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
BASE COUNT        23500 a        18119 c        15040 g        24110 t
ORIGIN      
        1 aacatatata cggcaaggcg aagctgacgt ggtttgaaga gatttttgaa aagtattaac
       61 acctacagac aagcctgacg atagcaagaa ctaccctact cgataggtat cggcttttgc
      121 tttctgaaaa aaattatttt aagcaatttg acaaatctag caacaaaaaa ttctataaat
      181 ataatagatt gaaactagaa tagtacacat ttgtttctaa aacattgtta gaaatcgatt
      241 tgactgtcct gaccgatttg tcctgttctt atttcatttt actatatttc catgataaaa
      301 cgcatagtat aaagttttct taatcccctg atactatgcg tgtttgtaat ttttaagatt
      361 ttgtgcttag agtcgactcc ttattttaga tatttaaaag gaatctcact tccacagagc
      421 cagttgtaga cttggtcatt gacaaataca ttcatggctt cgtgagcata ctcaggcatg
      481 atgcgatagg ttttatcgca ggtcagacga ttataaatcg caaactgggt aatgggatag
      541 caaacatcgt cgtccaagcc cgtaatcatc ttaacctcac cttggatacg atgggcaaga
      601 tttttgacat cgatataggc aagggtcgcc atgatttcct cctctgtttc atggaagggg
      661 tcgtgaaact tgaaataacg gaaaagttcg tcgtaagcct cgctagtatt accaatctca
      721 atcacccgtc tgaagtctga caagaaggga taaatggcaa ctgttttctg aattcgagga
      781 ttgagcgctg ctgcaactag agctagagcc cctccttgtg aggcaccata gctagaaaga
      841 cgcttctcat caacctgaga cagactagca acaatttcga ccaactggta aatatccaga
      901 taaacatcct tataaaagag gtggtcccga ccttccatag caccacggat aatatgcccc
      961 ttcacggtat ttcctaaagg agaacgcaag ccgtcttgtg agtaacctga ctggccccgc
     1021 acatccatgg aaacaacacc gtaaccagct acggtgaagc ccagcatgtc ggcccagtcc
     1081 cagccacgtc ccatataacc atgaaaatgg aagattagtg gaaccttctc ctcactcttt
     1141 ggaagaacaa tgcgtgcata gacctttcct tccttgcttc cttcaaatgt taactcatag
     1201 cacttgactt gaggaatgtg gaaatctctt tcctccaagt ggtaggatgg aggtgtggaa
     1261 acatttttca cttccccatc ccagaaagca tcaaagtctt ccggaacctc atcccttcct
     1321 ctataggtct taatttcttc tagcaaagct ggatttttca tagcatgctc cttttatttt
     1381 gtaatcgtta ccacaactgt agcatatcta tgtaatcaat gcaagaaaga aggataaata
     1441 gaaagtgaat ttagattctt tacttttagg atgatgggct gaaagtagtt ttagaaacga
     1501 aaaagagcat ttcgctctct cttctgttta tactagtttt ttgcttcctt cttttggaaa
     1561 gtggtttggt aatttacttt aatcgttact gtcatatgag agtcctcgtt tctttttgat
     1621 gactttagta taagagccaa acctaaaaac tagcttaagt tttccttaga gaaagcttaa
     1681 tccagatgtt ctttcttttc cagatgaagg gcaatcatgc gccactctgg atcttcttgc
     1741 caaacttcta tagaactaat gtagctagca acctttcttg cttcttctaa aatcggaaaa
     1801 tcttcgataa tatcagccac ttggaactct ggaagtcctg actgtctggt tccaaaaatc
     1861 tcaccagaac cacgcatttt caaatcttcc tccgcaagga caaatccatt ggtcgtttct
     1921 atcatgatgc gcatgcggtc tttcccagaa tccgtcttgg gattggcaac gagaacagcg
     1981 taggactgct tgtccccccg accgacacga cctctaagct ggtgaagttg actgagaccg
     2041 aagcgatcgg catccatgat aatcatgaca gtcgcattgg gaacgttgac cccaacctca
     2101 ataaccgtcg tcgaaaccag aatatccgtc tctctctcct tgaaatcctg catgatctgg
     2161 tctttttcgt cactcttcat cctaccatgt agaagagcca cctctgcctt gcctgcaaaa
     2221 tgagtcgtca actcctctga taaggcaatg gcatttttca aatctagagc ttctgattct
     2281 tcaatcaaag gagagatgac atagacttgg gaaccttttt gaatttcccc ctctaaccaa
     2341 gtcaagacct gaggtagttg ctcatgtttg atccagcgcg tcacaatagg cttccgacct
     2401 gctggcatct ggtcgataat ggaaacatcc atatctccaa aggctgtgat ggcaagcgtc
     2461 cgtggaatgg gagtcgccgt catcatgagg acatctggat tgtcaccttt ttcccgtaaa
     2521 atacgccttt gccctacacc aaaacggtgc tgctcatcga taataatcaa accaagacga
     2581 gcatactcca ccccatcttg tatcagagcg tgagttccta taatcaaatc agcctcaccc
     2641 ttggcaatgg tctccaagac ctctctcttt tctgcagctt tcaaggaacc tgtcaagaga
     2701 gccagtttca aattgggaaa aaggttctgt aaactctcaa agtgttgctc tgcgaggatt
     2761 tctgttggta ccattagggc agcctgataa cctgctgtca ctgccgcaaa catggccaag
     2821 ccagcgacta ccgtttttcc actccccaca tccccttgta ggagacgatt catgtggtgg
     2881 tcggacttca tatcagttaa aatttcctgc aaactctttt cctgagcttg ggtcagggca
     2941 aaaggaagac ttactttaac tgctgtcact ttttcctgag accaattcag aaccagacca
     3001 cttccctgaa ctctattttc agacttgagc atctgcagct gcatttggaa ataaaagagt
     3061 tcctcaaact ttatacggcg aagagcctgc ttgtattctg ccaaatcctt tggaaaatgc
     3121 atagctcgga ctgcctgaca acgggacatg agtttgtatt tgtctagtaa agactggggc
     3181 agattttctt ctatcaagag gtccagtccc tgatcaaaag ccgtcttgat gaccttaacc
     3241 agactggcct gactgattcc ctgagccaga cgataaacag gctggaggtc atcttctacc
     3301 tgagccagaa ccttcatccc attcagacta gccttagcgc ggtcccattt tccaaagaca
     3361 gcaagggttg ctcccaactc tattttatca gccagatagg gctggttaaa gaaattcacc
     3421 gcaaaaacga cctctccctg cttgagacta aaacgcaggc gattgcgctt gaaaccataa
     3481 tactggacac tagcaggagt cactacctga ccagaaagaa ctgccttctc accgtcttcc
     3541 agctccagca cctgcttggt tttgaagtct tcataacgga aaggaaagta gagcaagaga
     3601 tcttgcaagt tttcaattcc tagtttggcg tatttttctg ctgactttgg tcccacacca
     3661 ggcaagacat gcaagggttg atgtagattc atgctccact cctttctttt ctaataatat
     3721 tctctcggaa tacggtcgct gaggaggcaa accacctcat agttaatggt tacgcggtag
     3781 gtcgctacct gagttgcagt gatttcctta tccccattgg agccaatcaa ggttaccttg
     3841 gttcctagcg gataaagctt aggcaatcga atagtgattt ggtccatcga aaccctgccg
     3901 acaattgggc aagcttggcc atctaccaag acagagaaat tttgcatgtc tcttgtccat
     3961 ccatctgcat acccgattgg cacggtcgcg atgacttgct cgctatccgc ttgataagtt
     4021 gctccatagc ccatgcaagc tcctgctgga actgtcttga catgaaccag agcagactcc
     4081 aaggtcaagg ccggtatcaa atcataaggc aaatccaaga ccgctccact tggattgagg
     4141 ccatacatgg catctcccat acgaaccgca ttgaaaatag tctctacatg ccaaagagtc
     4201 gttgcagaat tgctagcatg aaccagctct ggaacttcct tcatactagc taaaatagtt
     4261 ttaaaccgtt ctaactgggc attaaaatag tcatctgatt cctcatcagc agtagcaaag
     4321 tgggtaaaga ttccttcaac acgaacaccg tgttgttgta gcaaatcttg agcctgctca
     4381 acctcactgg cctctctaaa accaatccgt cccatccctg aatcaatctt gaggtggact
     4441 gtcaatccag ttaggtccac ttccttatct aagagtgctt gaatccactc cagtccagcc
     4501 actgtcaagg tgaagtcata ttctttagct agagcaacag cttcgatttc agaaactcct
     4561 aaaatgagga ttggcttgct gagtccagct tgtctgagtt caatggcttc atcgatattg
     4621 gaaacgcaaa agccatcaac atcatcttga attgccttgg caacggcaac agctccatga
     4681 ccataagcat tggccttgac cacagcccac ttgagcgttc cttgagggat atgagtcccc
     4741 atttgctgaa tattttgtcg aatagctccc agatgaatca gaaccttggt tggtctatgt
     4801 ggactagctt tcatgatttt cctccaaaat gacactggct gtcacaaact gatcggtgtg
     4861 gctgatagac agccaaatct ttcctgaaaa tggtgcctga ctaaaataag gcgccccacg
     4921 ttcattgttc aatacttcca aatcctgaaa accgagcttg ctaatgcccg ttcccatagc
     4981 cttggaaaag gcctccttag ccgaccagcg accagctaaa tattctattt gcctgcgtcc
     5041 tttgagactg gtgaagcgct ccatttcctg agcagtcagt acacgcttag caaatccttc
     5101 atgtcgtgta actgcgcttt ctatcgaagc caattcttcg atgtcaattc cgtgtccaac
     5161 tatcattttc atcaaaagga gttgagattc cccaactcca tccttttcac ttattttgtc
     5221 aaggtaacat aaatctcttc taccaaggcc tctgtatttt cccaacctag gcaagggtca
     5281 gtaatagagc aaccaaagat ctctggttgg ttttgacgac catctgctag gtaagattca
     5341 atcataaatc ctcgaaccgt ctttttaatt ttctcattcc aatcacgatt ctgcaaggtc
     5401 tggcgaacaa ttcgaatctg ctccatatat tgcttgcctg agttatcatg gttggtgtca
     5461 atgaggataa aaggattttc aagtcccatg gtttcatagc gttcaatggc ttggagtagg
     5521 ttttcatagt agtaattcgg catataattg ccatactcgt tgactgctcc acggaggata
     5581 acatgggcca aaggattacc tgatgtctca acttcctgcc catgataaag gaaggtttgc
     5641 ttgttttgag cagcatagat ggcgttaaac ataacaccca aatttcctga ggttggattt
     5701 ttcatcccta ctggtgcatc aatcccagaa gccacaaagc ggtgctcttg gtcttccaca
     5761 gaacgagctc caacggcatg gtagctgacc aagtcatcca ccaagatcag atttgacgga
     5821 taaagcatct catctgccgt tgttaaacca gtctctgtaa tcacgcggta gtgcaactgg
     5881 cgcacagcct gcaagccgtt aatcaggctt ggagccttag aagtatctgg ctggtgaacc
     5941 aatcctttat agccgtctcc attggtacga ggcttagcag tatacacgcg catgaccatg
     6001 aaaatcttat ccgctacctt cttttgcaag gcggataaac ggcgagcata ttccaagacc
     6061 gcctcttcat tatcagaaga gcaaggacca atcaccaaga gaatacggtc atcttcccct
     6121 gaaataatat ctgccaattc cctgtcacgg ctttccttga gtctcaaggc ttccgcagac
     6181 aattgggttt cagccttgat gacttccata tcgatttctt gacctttttc aataaatgcc
     6241 atcttattct cctaacgttt tgtaaatttc tctgacaaga gcttctgtgt tatcccaacc
     6301 caggcaaggg tctgtgatag acttaccaaa tacttctggc tcattttgtc gaccatcttc
     6361 cagataagac tcaatcataa aaccacgaac gaactgctta attttttcat tccaagcacg
     6421 gttaatcaag gtctggcgga caattcggat ctgttcaata tactgcttac cagaattgtc
     6481 atgattggta tcaatgatga taaaaggatt ttccaagccc attttctcat actgggcaat
     6541 ggtatcaatt aaattgtcat aatagtagtt gggaatattt tttccatact cattaagagc
     6601 accacgaaga atagcgtgtg aaagcgggtt cccagttgtt tctacttctt ttcctaagaa
     6661 aaggaaactt tgtttgtttt gagcagcata aattccatta aacatgacat tgagatttcc
     6721 agaggttgga tttttaaaac cagtagaaaa tcctgcccca cttgccacaa agcggtgttg
     6781 ctggtcttca actgaacggg caccaactgc catgtaagaa atcaaatcat ctacaagcgg
     6841 aaggttttca ggataaagca tttcatcagc agttgtcatc cctgtttctg tgatgacacg
     6901 atagtgaaga tggcgaacgg ctttgattcc attgataaga ctaggcgctt ctgtcgcgtt
     6961 aggctggtga atcaagccct tatagccatc tccgttggta cggggtttgg cagtataaac
     7021 acgcataacc ataaagatac gatctgccac ttcttcttgt aggactgcca aacgcttagc
     7081 gtattcaagg acagcttctt cgttgtcaga tgagcatggc ccgattacca agagaattcg
     7141 ctgatcttct ccacgtataa tggcttctag ctcttgatct cgctgtgatt tcctctccaa
     7201 agcctgacct tctaattttg acaaggcacg aacttcttct atatttattt tagagctttt
     7261 tgctgtaaat accataactc atctccttat aaagcaaacg gatacccagt aaaaatttac
     7321 ttttcacaag atatccgcct ctaaactatc tcattttatt gtcttttacc gtgacagttt
     7381 ttaaatttct taccagaacc acatgggcaa agttcattgc gtccaatctg gctcaaatcc
     7441 aaatcttctg gcatacttgc ttggtgagca gcgatattgc gagtcgctgt tgtactgata
     7501 tgacgttctg cctgtggtct ttcttgttca tgaatttgtg ctttcatcat caagcgtgtc
     7561 acatcaaact caatcgaacc aatcatatca ttaaacatac ggaaaccttc tgcctgatac
     7621 tcaacaacag ggttgttctg agcatagcca cgaagtccaa ccgcgttacg caattgatca
     7681 agggcatcga tatgatctgt ccacttgtta tccaccactc gtagaatcaa aactttttgg
     7741 aattctttaa ctgcttcttc atcgcgtagt tttgaaacct gactatcgta aaccttcaag
     7801 gcacgttgga aaagctcttc cttgatggcc ttatcagaca agcctgacaa gtcttccatc
     7861 gtaatagaat cttcaggaag caagttgtac ttagcaaagt tcaaaattgc ctctagtttt
     7921 tcatcttgtt tagcacgcgc atgaccgtca acgacacgtt caatcgtgcg tttgatcata
     7981 gactgaattt caggtgccaa gtcacgatct gcagtgatga catcgtaacg ttgagcatag
     8041 ataatctcac gttgttcacg catgacatca tcgtattgaa ggacttgttt acgggtatcg
     8101 tagttatttc cttcgacacg tttctgagct gcttcaacct gacgcgtcaa catgcgagac
     8161 tcaatcgcct cttcagacat gttgagacgt tcaaagattc ccttcaagcg ttcagaacca
     8221 aaacgtttca tcaaatcatc ttcaagagat aggtagaatt gtgactcacc tggatctcct
     8281 tgacgacctg aacgtccacg aagctggtta tcgatacgac gactttcatg acgttctgta
     8341 ccaataacac aaagtcctcc aagttcacga acaccttcac caagcttgat gtcggtacca
     8401 cgacccgcca tgttggttgc gatggtaacg gcaccacgtt gaccagcatt catgatgatt
     8461 tgggcttctc tatagtggtt tttggcattc aagacttcgt gaggaacacc agctgcgacc
     8521 aatttcttag aaatgtagtc actagtttca accgctactg taccaaccaa gacaggttga
     8581 cccttttggt aacgagcctt aacgtcttcg acaaccgctt taaacttaga ttcgatactt
     8641 gcataaagaa ggtctgagtg gtcaatacgt tgaacaggac ggtttgttgg gattggaata
     8701 acacgaatgt tgtagatttc acggaattct tcttcctcag tcttacctgt acccgtcata
     8761 ccagacaatt tcttgtacat acggaagagg ttttggtacg tgattgaggc agatgtcttg
     8821 gtttcatcct ggattggcac accttctttg gcttcaatag cttggtgcaa tccatcagaa
     8881 taacgacgac cttccatggt acgacctgta aattggtcga caatcaagat ttcttgctct
     8941 tcgctcacca catagtcaat atcgagaagc atgatgtagt tggcacgaag ggcgttatcg
     9001 ataaagtggg tcaaagccac gttttcgatg tcatagaggt tttcaagttt gaagtagctt
     9061 tcagccctgt caatccctga atcagacaaa ccaatagtct tagactgcac atcgatgatg
     9121 tagtcatctt tgttcaaaga ttttacatag tggtctgcca tgtgatacaa ctgactggtt
     9181 tcaaccgcat tggcacctga tacaatcaaa ggtgtacgag cctcgtcaat caagatagag
     9241 tcaacctcat cgaccaaggc atagttaagc ggacgttgta ccatgttttc agcgcgaacg
     9301 accatgttgt cacgaaggta gtcaaatccg atttctgagt tagttgagta agtaatatca
     9361 cactcatagg cttctttttt ctccattgga gatttggtag ccaagttaat ccctactgac
     9421 aaaccaagcc aagagtacaa ttcacccatc tcagtcgcgt cacgttctga caggtattca
     9481 ttaaccgtaa ctacgtgaac ccctttacct gaaagggcat tgaggtatac cggcatggtc
     9541 gcagtcaagg ttttcccttc ccctgtacgc atctctggca cgtcaccatg gtgaagaaca
     9601 atccccccca tgacctgaac cttataaggg aagagaccta ggacacgttt ggcaccttca
     9661 cggacaaccg caaatgcttc gtaaagcaat gaatccagtg attctccatt ttgataacgt
     9721 ttcttaaatt caactgtttt tgcttttagt tggtcgtcag tcaaagcagc catttggtct
     9781 tcgtatttga aaaccttgtc agccatcttt tccagacgac ggatttctcc tttatcattt
     9841 tcgataattg tttttaaaat attagccatg tttttcctta ctttaaattc cgaatatttt
     9901 agaatgttcc tttaatttta gcacaattac tgattatttt caaggaagaa tccccatttt
     9961 gaaaaggaaa aagaggttag ttttcaagct aacctctccg acttttatga ctgtttaatt
    10021 gccaaaaatt ggcaaaatgg caaatgtgat aaataagtta attcaaagag aaagacagca
    10081 aatcagtcca aaaacaaaga gactgacttt cttggacagc aaggccatca aaatggacag
    10141 aattccaaaa actagcaaga ttttctgtat gatgaagatg tcaatcctta cccccagaat
    10201 cgctctatcc caagggataa agaagaaaga cagccagatc agcagaacta aaccaatata
    10261 aaccttggaa tagcgtgtaa taaatgattt tagatgtgcc acaagccatc tcctaggatt
    10321 gtatatcctt tacatttgta tatgtccatt ttcgacaact aatacatctg tacaaaggtc
    10381 tgaaatatct tccgatatgt gcgacgtcag gataaccaga ccattttctt ttttcaggta
    10441 agataaaatg acctgtttgg ttaacctcac actcttctca tccaaagcat tcataggttc
    10501 atcgagaaag agtatagaag gagaggaaat aaaggcttga atcaaggcca ttttttgctt
    10561 tgttcccaag gataaatgcc ggtattcaac gtcttcaaat tcctgtaaat catagtattg
    10621 aatccaatag gcaattcttt tttccgtaac tttagatgaa aaatacctta acagttccaa
    10681 attttctctc agggataaat gagataaaaa ctcgactttt tcaattaaaa ttcctgcatc
    10741 ctgaatataa tgatttttta tcccgtaaac tttaccatct tgaagaactt ttcctttgtc
    10801 aagcttaata taaccagcaa gtacctttaa aagaaccgtc ttgccagatc cattatcacc
    10861 tttaagtcca taaatttttc ctgattgaaa caccaaattc aactgattta aaataggtct
    10921 tttcccataa attttctgtc catttataat ttcaagtttc atcgtttatc ctttcttaaa
    10981 tttctcttcc aagcgactaa caatcaacat aactaataag cttaagagta gtaaatacac
    11041 tgttacaata tgatccatca tccattcttg tcccacaaat gctaaaaaat agagaaaaaa
    11101 ggaaaaacca gcgcccgcac taatcagtgc tatcagataa gacagtagta agtacaacat
    11161 cattaactga gcaagtaaaa agaaaagtgc gactgttttg aaatgaattc ctagcggaag
    11221 taaaccaagg aaccagacaa gtaaatcttg agtaaaaaat ttagaaatga caaccaatcg
    11281 tttccttgta taatcgaaaa aggagcttga ttgatagcga atcaagtgat ggtaatggtc
    11341 tgccaaatca ctttcaagta aaatgacaga gagccatcct accatgaaaa gcgaaaggtt
    11401 taacaagagt ttggggattt ctaaattcgc ttcagaatag tcattatagg aaaagattga
    11461 aatcaattct ctcttgaaaa agataacagc atcctgcttt tgaaccgctg ttgacaatag
    11521 atagtttatc aaaatcatca tcagaactat acgaagtagt aaaacgatct ttctctttag
    11581 ccaaatattg ttaaaattct taaacattat cttcatattt ttcaagcacc atataaggga
    11641 caatataaag gatataagga gtaaagagtt tcatcaaact tacatcccca tagctagctt
    11701 gcatcaaact cgtcatagga accatatagt aaggcaaggc actatagagc agcatagaac
    11761 caagccaaag aaacatcaaa taggtgattg ccgaacgagt cacattcccc acataatcaa
    11821 ctatttgtaa aaaatagatt gcattgatga aaataccgat tagtaggaca caagtaaaga
    11881 acaaatagct ttttatctct ccatctagga gtctttgtaa accacttcca tcagaaaata
    11941 gagaattcca tccaagagga gaaaaagtcc caaagaaata ggttataatt gcaattatca
    12001 gcacagtcac taaatatatc aaacaaggga tacttgcaac ttgcaaagtc aactttcttt
    12061 ttaacccttg ataactcact tctcttccaa tactcaatcg taaaacttta tttttcagct
    12121 caatatattg aaaacctagc aaaacaatga tgattggaat aataaatgat tgataaaaac
    12181 ctagattgaa ctggagaata cgaaaatcta atgctgattt taataagtca tttttaattg
    12241 cttgtccatc gaatttagct agatcgggcg catgaatatc aaaaaagaaa taagtcatca
    12301 aaacatcacg ataaaccaaa gcaagaaaaa gcaaagtaag caagacataa acaaatttat
    12361 gccttgccaa agttaagaga ggaatcttca taagccacct cctacaaata gaaagtaata
    12421 taatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaagttg ctcaaagcac
    12481 tgctttgagg ttgtagataa gactgacgaa gtcagttaca tatataatcc aaggcgacgt
    12541 tgacgtggtt tgaagagatt ttcgaagagt ataaatcaat gccttacgcc tttagacttc
    12601 cctagttccc gtctcaagtc aagcattttt ttgaaacaga tatagtctaa ccagtcacta
    12661 gcaaaagcga taagtagtaa taatagccaa ataccccata acttgatatc tgtcaaattt
    12721 ctcaagacga tattgaaaaa cagaactgaa aaaactgtcc aagcaaggct aaaaagagaa
    12781 tagagggtga tgtaaatcca gtaaaaatag taaaaaattg ggaaaaattt actttctcta
    12841 ttatccttgt caatccagct gaaaaagtaa aaacagggta ataagattat cattttaaac
    12901 aagtgttcca tcacaagcct ccttttttaa attgttttct ttagtttcgt tctattaaat
    12961 attattatca atataaacct tggaatagcg tgtaataaat gattttagag gtaccataag
    13021 ccacctccta caaatagaaa ccgatataaa tcaatgcctt ccacccttag acttccctag
    13081 ttcctgtctc aagcgaaaca tttctttgaa acaggaataa gttaaccaat tcataccaat
    13141 agctagcaga ataaaaagaa accaaatgcc ccataacttg atatctgtca catttctcaa
    13201 gacggtattg aaaaacagaa ctgaaacaac tgtccaagca aggctaaaaa gagaatagaa
    13261 ggggatgtaa aaccagtaaa aataataaaa aattggaaaa aacttactat ttctgttggc
    13321 cttttcaatc cagttatcaa aataaaagta cggtgctaaa agtaagaatt taaacaaatg
    13381 ttccatcacc gacatcaccc tccttctttt gatagcgttt tctattattt tattatatca
    13441 aaaaaatccg gaactgtcat tccagattct acttttttat ttgcgttttc ttgcgatgag
    13501 atgaatcggt gttccctcaa aaacaaaggc cttgcggatt tgattttcca agaaacgcag
    13561 gtaagaaaag tgcatgagtt cttcttcatt gacaaagatg acaaaggttg gtggtttggt
    13621 tgccacttgg gtcgcataga aaatcttgag acgttttcct ttgtctgtcg gtgttgggtt
    13681 gatggcaatg gcatccatga tgacatcgtt caagacagct gatggaatac gtgtattttg
    13741 actttcgctg atttgcttaa tcatctcagg aagtttgtgg agacgttgct tggttaaagc
    13801 tgatacaaag ataatcggtg cgtaaggcag gtattggaac tgctcacgga tatcttcttc
    13861 ccagtttttc atagtgtggt tatctttttc aagcgtatcc cacttgttga ccacgataat
    13921 catcccttta ccagcttcat gggcaaatcc tgcgatacgc ttgtcgtact cacgaatgcc
    13981 ttcttccgca ttgatgacca tcaagaccac atctgaacgg tcaatagcac gcatggcacg
    14041 cataacagag tatttctcag tattttcata aaccttacca gacttacgca taccagccgt
    14101 atcaatcatg gtaaactctt gaccatctgt atctgtaaag tgggtatcaa tggcatcacg
    14161 agttgttcca gcaacaggac tagcaataac acggtcttcg cccaagatag cattgatcaa
    14221 gcttgatttt ccaacgtttg gacgaccaat caggctaaac ttaatgacat ctggattttc
    14281 ttcttcatat tcatttggaa ggttttccac aatcgcatct agtacatccc ctgtaccgat
    14341 accatggaca gatgagatag gcagtggttc acccaaaccg agggcataga aatcatagat
    14401 atcatttcgc atctcagggt tgtccacctt gttaactgcg aggataactg gtttgtgggt
    14461 cttataaagc ttacgggcta cgtattcgtc tgcatcggta attccttcct taccggacac
    14521 gacaaagacg ataacatctg cttcttccat ggcaatttct gcctggtgct tgatttgttc
    14581 catgaaagga gcatcgacat catcaattcc tcctgtatca atcatgctaa aagaacgatt
    14641 gagccactca cccgttgcat aaatacggtc acgtgtcact ccttcgacat cttctacaat
    14701 ggagattcgc tcaccagcga tccgattaaa tagggttgat ttcccaacat tgggacgtcc
    14761 tacaatggca atagttggta gggccataat ttctcacttt ctacaataat ttcttctgtt
    14821 caagattttt tctagttgag cttggttcag cttgaccaaa ctgttctgct aggcgctgac
    14881 tccagcttgt ggtcgcacgc gccccagcat agtcagcctg aacacggtca taagcttgga
    14941 ttgcctcagt tgactgttct tggtattctt cctcaaagac aacattctct agtggcagtc
    15001 tcggtttcat atcatgatgt tgatttggca cacccagtgc catcccaaag acagaatagg
    15061 tgtagtcagg caggttaaag agctctgcca cttcttcaga cttgtatcga accaaaccga
    15121 taatcacacc accatagccc aagctttcag ctgccaacaa ggcgttttgt ccagcaagag
    15181 ctgcatcgac cgaactaatc aagagacctt ccacaccttg gggttggaag gtgtcggtat
    15241 gaagtcgggc tcccttttct gctcggttca aatctccgac aaagagaagg aaaacagcag
    15301 actggcgaat ggcttcttga ggtaccaatt catacaaggc atctttcttc tcttgacttc
    15361 gtaccacaat cacagagtag gattggaaat tcttccaaga tgatgccatc tgggctgctg
    15421 tcaaaatctc atttaagtct acttggggaa tttcttgctc tttaaacctg cgcactgaag
    15481 tatgagcctt catcaattta atggtttctg tcatcgacgg tttactcctt ctaaacgagt
    15541 ctcctcagcc aaataacgga tgcgttccat gacccgtctg gcttcccagg tttcgtcatt
    15601 tccatgtttc actttcgcaa aatgcttctc caaatcttca aagttgaagt tggatgtgaa
    15661 aaaggtcggt aaattttcct gcatccgata ttggagaatg acctgcagga tttcgtcacg
    15721 cacccaaacg gttgattgct cggcgccaat atcatctaaa atcaggacct cagacagctt
    15781 aatctcatcc accaaggtct taacattgcc atcactgata gcatttttga catcaatgac
    15841 aaagctagga tagtggagga gagttgatga aacaccacgt ttttctgata aatcatgagc
    15901 taaggccgcc accatgaaac ttttacccac accaaagtct ccatataagt aaagaccttt
    15961 tcgaatagct ggatattgct ccacgaaggc tagtagcttt tcaaaaactg gtaagcgccc
    16021 caaatcatcc aagtcaactt gagccaaact agctttcttg agactggctg gtagattgat
    16081 taacttgaga cggttcttaa tagccgcttc tttttcagcc gcgattagct caggagtttc
    16141 ttcatatgaa acatctgcat agccatgatt cttaaccaaa atcggcttgt agcctttggc
    16201 aatataatcc gtatccccac ggagaaactt gtcacgctcg gtgatgtact gattaaactt
    16261 ggagatactg cgatttaatt cctctggagt taaggattct tgctggataa aggccgcaac
    16321 atcagggtcc ttcatgattt tctggaccaa atcttgataa taaaaacggc tgggttgacg
    16381 tttgagtacg tctccgacac tttccatcta atctcctcct ttttctaatc gagctaatag
    16441 ttcttgcttc ttacgttcta gttccagacg agtttcctcg ctggtttcat tcttatattc
    16501 aggattactc catttaggaa cattggtttt ttctggggca gtctgattct gtttttgtgt
    16561 ttttgctttc tgccctcgat cacgaattcg taaaacggcc tcttctgccg aatgaatctt
    16621 ttgataggca tagtcattgg ctaccttcat ggcatatttc tcattgatat ttgccgaatc
    16681 caccttatta aaggtcaata agagaataat attgatgact tcgtccagta agcccaagcc
    16741 agccatctgt tgcaagagtt ctctttctgt ttgggtaatg gttcccttgc gtgtttgctt
    16801 gatttctgct aagaactgca gggcagtttt acttttagct tctttgataa tggtcgcttc
    16861 cttaagacta aagtcagagg aaactggttt ttgagcaatt ttttcacgca tgcgtttggt
    16921 tgaaataacc tgggaaacag ctgttgactt ggccaattga taggtttcaa accaagtcca
    16981 tttcttctcc tcggcaatag caaagaggtt taagacatcg gactgctcat ccgcaaaacg
    17041 aagtccatct cgagccatca gctggcgaaa atgttccaag tcaaaatcat tggccacttt
    17101 cttcttgaga ccaaggtctt cttgactgcc tagttctgcc aattctggaa agacttgatt
    17161 gagtgagaca ggtatttctt caccatcagc actttcaact ttcaaatcct ccacagctac
    17221 atcgccaatc tttttctcta agagtctgcg ataaacagga tgccccaaga agtcttgact
    17281 agatagagga gcatggaggg ctagctgata aacatcaccc ttttgataga gggtcaagag
    17341 attaaaagca gataagattt tcaatgattt tatcagtcta tccatcccaa agttgagatg
    17401 gttgagaatg cttgaaaaaa gatattcctt tctaccatta tcccaaaaac tgattgtata
    17461 aagataaagg ctcagtgcct cctgaccgat aatcgggagg tagcactgta ccagagatga
    17521 ggtatcttgc gacacccgat tattctttag ataagaaaaa cggtcaattg gcttcattta
    17581 tctttccttt ttctttttag aggactgggt gatttgttgg agcaagctct ctaactcact
    17641 gacatcctta aaactacgat agacactagc aaaacgtaca taggtaatct cgtccaattc
    17701 agccaactcc tccatgacga gtgaaccaat gtcctcactt tgaatttcat tttcatttcg
    17761 accacggagt ttctgttcga tacgattgac taccatgttg atttcatcac ttgacacagg
    17821 acgtttctgg gctgagcgga taatcccatt aaagatttta tctctggaga attgttcccg
    17881 tgtgccatct tttttaacaa ccactaaggt tctttcttct actcgttcgt aggttgtaaa
    17941 acggtgttgg cattcgtcgc actcacgtct tctacgaatg gtgttccctt cttctgcttg
    18001 gcgactatcg ataacacttg acttggtagc cccacatttt ggacaacgca tcctttccct
    18061 ccttatcgtt ttcttttcat tataccattt tttaagcgat tcccaaaaca attcttcttt
    18121 ttgcttgaca agttttttgt tttgttgtat tatttaatta agacaacaag gtaaaagaaa
    18181 ggagactaag atgtcctgga catttgacaa caaaaaaccc atctatttac agattatgga
    18241 gaaaatcaag cttcagattg tttcccatac actggaaccc aatcaacaac ttccaaccgt
    18301 gagggagcta gctagcgagg ctggtgtcaa tcccaatacc atccaaagag ccttatcaga
    18361 ccttgaacga gaaggatttg tctacagcaa gcgaacaact ggacgatttg tgactaagga
    18421 taaggagcta atcgcccagt cacgcaaaca attatcagaa gaagaattgg aacacttcgt
    18481 ttcctccatg acccattttg gctatgaaaa agaagaacta ccaggcgtag tcagtgatta
    18541 tattaaagga gtttaagcct atgtcattac tagcatttga aaatgtatcc aaatcatatg
    18601 gagcaacacc agcccttgaa aatgtttctc ttgacattcc agctggaaaa attgtcggcc
    18661 ttcttgggcc aaacggctca ggaaaaacaa ccctgattaa actaattaat ggcctcttac
    18721 aaccagatca aggacgtgtc ctcatcaacg acatggaccc aagcccagca accaaggccg
    18781 ttgtagctta tttgcctgat acgacctatc tcaatgagca aatgaaggtc aaagaagccc
    18841 taacctactt caagaccttc tataaagatt tcaatcttga acgcgctcat catctacttg
    18901 cagacctggg cattgatgaa aatagtcgtc tcaagaaact atcaaaagga aacaaagaaa
    18961 aggttcaact gattttggtt atgagccgtg atgctcgtct ctatgttttg gatgaaccca
    19021 ttggtggggt ggatccagca gcccgtgctt atatcctcaa taccattatc aacaactact
    19081 caccaacttc taccgttttg atttctaccc acttgatttc tgatatcgag ccaatcttgg
    19141 atgaaattgt cttcctaaaa gacggaaaag tcgtccgtca aggaaatgta gatgatattc
    19201 gctacgagtc aggtgaatcc attgaccaac tcttccgtca ggaatttaag gcctaagcaa
    19261 aggagattat ttatgttttg gaatttagtt cactacgaat ttaaaaatgt taacaagtgg
    19321 tatttagccc tctacgcagc cgtgctagtc ctttctgccc tcatcggaat acagacacaa
    19381 ggctttaaaa atctacctta ccaagaaagt caggctacta tgctactttt tctagctaca
    19441 gtctttggtg gcttgatgct tacacttgcg atttcaacca ttttcttgat tattaaacgc
    19501 ttcaaaggta gtgtctacga ccgacaaggc tatctgactt tgaccttgcc agtttctgaa
    19561 caccatatca tcacagccaa actaatcggt gcctttatct ggtcattgat tagcaccgct
    19621 gtattggctc taagtgctgt tattattctg gctttaacag ctccagaatg gattcctctt
    19681 tcttatgtga ttacatttgt agaaacacat ctccctcaga tctttcttac aggtatatcc
    19741 ttcctactaa ataccatttc aggaatcctc tgcatctacc tggctatttc cattggacag
    19801 cttttcaatg aataccgtac agcactcgct gttgcagcct acattggtat ccaaatcgtc
    19861 attggattta ttgaactttt cttcaatctt agttctaatt tctatgtcaa ttcactggta
    19921 ggactcaatg accatttcta tatgggagca ggtatagcca ttgttaaaga actcatattc
    19981 atagctatct tttatctcgg aacctactac atcttgagaa ataaggttaa tttgctttaa
    20041 ataattttta cctagatatg taacatactc atagaacaaa agagaccagg caaaaagtct
    20101 ttaaaattag aaaacgcata gtatcaagtg ttaaaaatcc ttgatattat gcgttttttg
    20161 tgagttgact tatttccttt cactatatcg caaaatgaaa taagaacgga acgatgggat
    20221 tttggaattc aaatcaattt gtaagaatgt tttagaagta atattatcct attccagatt
    20281 cagttcacta tacaattgag ttttcaagca acttgtttac ataatgtgta cataattagg
    20341 ttcgtgattc cacccttttc acctttaaaa acctcgcttt cgcaaggctc ttctatttat
    20401 aagataaggc acgtttaaag gttttccaaa tccctaaatc atccgtttga agaacgagac
    20461 tagcatacat gcgtccgata aatcctgttg ctaccaccgc aaaaatcact gtaatagcaa
    20521 gtgaaatcca tgcttccgct ccccccgcat agccattaat cgttcgaaac ggcataaaga
    20581 aggtcgaaat aaagggaata taagaaccaa tcttcaagag gagattgtca ccagctgcac
    20641 ctagagctgt cactccaaaa aaaccaccca taatcaaaat catcaaaggc gacaaggctt
    20701 tccctgagtc ctcaggacga gaaaccatag atcctaggaa ggctgccaag actacataca
    20761 tgaaaagact gatcaaaata aagagcaggg tattcagtga gatagcatct cccaagtgat
    20821 ccaaaatacc agactgagcc aagaatggca aatctttaaa gagcaaaacg gcagccagac
    20881 cacctacaac atagatccca atatgcgtta aaatcactag aaacagagcc atcatccgcg
    20941 catagaaata gtgacttgcc cttatgctag aaaaaacgac ttccataatt ttggtgcctt
    21001 tttcactggc aacttcctga gctgttacac ccgcataggt aatcagaatc atataaagaa
    21061 agaatcctaa ggcacctgct gcaattgttt gaataaactt tttattttcc ttggcttcat
    21121 caatcttttc tgtgaattga attgtctgcg ctaagcgttt ttcctgctct tgagacaagg
    21181 aagcagttga acgattaagc tgattttgca gttcattgag tgtacctgta acctcaaatt
    21241 taattccatt ttcaagcgat gtttcgccat gataaactgc ctttagaaca ctatcttctt
    21301 gatcaatggt caaataacct tttaattttt cttctttaat tgcttctttg gcacttgctt
    21361 cgtctttata gtcgaagtta acaccattta cattcttcag tccttctgct acagatggca
    21421 ctgttgtcac tacttccact ttattatttt tagccataga agaaccttgg agatgcccaa
    21481 ttcctacaga gattcctaaa aagaggaacg gcgaaatcac cataaagaag aaactccatg
    21541 actcgacatg tcgaagatag gtttccttga ttacaaccca catatttctc atacttccac
    21601 tcctgattct agtttaaaga tttcatcgat agttggcgct tgttggtcaa atgttgcgat
    21661 atattgacct tgagtcaaga ttgggaagag ttcccttcca gcgctctcat cctccaaaat
    21721 caatttccaa ctgccttgtt tggtcaagct cacctgtttg acatgaggaa gattttccaa
    21781 ttcttccttg cttcgttcac ttgaaacaaa gagacgcgtt ttcccgtatt gattgcggac
    21841 atcctgaact ggtccgtgca agaccacacg gccatctcgg atcatcagaa tatcgtcaca
    21901 aagttcctca acattggtca tgacatggtc agaaaagata atggttgctc cgcgctcttt
    21961 ttcctgaaaa atgacttgtt tgagcaattc tgtattaact gggtccaatc cactaaaagg
    22021 ctcatccaag ataatcaggt ctggttcatg aatcagagta ataatgagct gaatcttctg
    22081 ctgatttcct tttgacagac tcttgatttt atctgtcagc tttcctttca cttccaacct
    22141 cttcatccat tgagggagtt tttctttgac ttctttggca tccatgcctt ttagagtcgc
    22201 caagtagcga acttgttcaa gaactgtcaa tttaggcatg agactgcgtt cttcaggcag
    22261 ataaccaatc cgagcatagg tctcctgacg aatatcctga ccatctagac cgatttctcc
    22321 ctgatattct aggaatttca aaatactatg gaaaatcgtt gtttttccag caccattttt
    22381 tccgactagt cccaaaatac gacctggtcg cgcttgaaag tcaataccaa acaaaacttg
    22441 cttggagcca aaacttttct ctagacttct tacttctagc atctttcacc tccgaaattt
    22501 cttgcactca ttatactcct ttttgatagc ctttacaatg ttttttgtcc atttttagaa
    22561 gactattgct gtgtaaaata tggcctggag cacttttata ctcaatgaaa agcaaagagc
    22621 aaactagaaa gctagccgta ggctgctcaa agtacagctt tgaggttgca gataaaactg
    22681 acgaagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagtaact
    22741 atatctacgg caaggcgaag ctgacgtggt ttgaagagat tttcgaagag tattagtgat
    22801 aaatccatta tacagtagca aacttaattt ataccttccg ctcctcaact gtctattttt
    22861 aatcctgaat tgttatttga gtaactcctt tttcctcata aagttttctt cctctaaaac
    22921 ttctggaaaa aagcgaatag tttcagataa catttttata aggaacaagt tcatctgtca
    22981 tttcaagaag gagtaatcct ttatctacta atggacggaa cggaattcaa ccgcttgtcc
    23041 gatatgtttt ctaaggatta tatagtaaaa tgaaataaga acaggacaaa ttgatcagga
    23101 cagtcaaatt gatttctaac aatgttttag aagtagatgt atactattct agtttcaatc
    23161 tgctatatct attatgcaca ccactatagg atctaataaa aatcacaaca agttcattca
    23221 tagatggtta cctcagggaa ctaagaaaac gactacaaag gaagtcgcat tcatcgaaaa
    23281 gtggattaac aactatccta aaaaatgctt gaactacaag tcccccagag aagacttctg
    23341 gatgactaac ttgaacttga aatttagcaa taattaattc accatctaac tatatttagt
    23401 aattatttca gaactgatta atattaaaat taactaacaa ttcaaaggat tcatactagc
    23461 cataaattac gtccatcaga gagagactct tactactttt agattttagt ctttctagct
    23521 tcagaataca tctaaacttt agggaaaatg actattcgaa agcgcgaatg cctcaaaatt
    23581 atctcagata agctattcga aacttagaat gcttttaaat ttatggaatt gcgattattc
    23641 gaaacctaga atgcatataa cctttagttg acagacctat tctaagtctc gaagggctat
    23701 ttactttcta ttccttatca aaaaagactc attccccctt tctcctccaa aatatggtat
    23761 agtagaaata tactatctat gaggagttta catgtcacag gataaacaaa tgaaagctgt
    23821 ttctcccctt ctgcagcgag ttatcaatat ctcatcgatt gtcggtgggg ttgggagttt
    23881 gattttctgt atttgggctt atcaggctgg gattttacaa tccaaggaaa ccctctctgc
    23941 ctttatccag caggcaggca tctggggtcc acctctcttt atctttttac agattttaca
    24001 gactgtcgtc cctatcattc caggggcctt gacctcggtg gctggggtct ttatctacgg
    24061 gcacatcatc gggactatct acaactatat cggcatcgtg attggctgtg ccattatctt
    24121 ttatctagtg cgcctatacg gagctgcctt tgtccagtct gtcgtcagca agcgcaccta
    24181 cgacaagtac atcggctggc tagataaggg caatcgtttt gaccgcttct ttatttttat
    24241 gatgatttgg cccattagcc cagctgactt tctctgtatg ctggctgccc tgaccaagat
    24301 gagtttcaag cgctacatga ccatcatcat tctgaccaaa ccctttaccc tcgtggttta
    24361 tacctacggt ctgacctata ttattgactt tttctggcaa atgctttgac acgtaaaaaa
    24421 tccgtttggt ttcccaagtg gatttttaaa gcgtagatta actatagctt gatactaaat
    24481 atactttggt atggaaatca tgcatatttt tcgatagtga ggcgaggact tacctagcct
    24541 ttccgccgtg atagaaacac ctgaaatcta atggtttcag gtattcggaa actttgagac
    24601 actaggctca aagtttaggt atggaatttc gaagaaagtc gctaccgtcc gtaatcactt
    24661 aaggaaaggc tcaaaaatat tgttttcaac cacaaaatcc gtttggtttc ccaagcggat
    24721 tttgtgcttt attttgaaac ttcttttgca agaacaaagt tcccaagtgt ggcagaacca
    24781 tttcctgcga ctgctggcgt cacgatatag tcacgcacat ctggtactgg taggtaacca
    24841 ttaagaagag atgtaaattt ctcacggaca cggtccagca tatgttgttg agccatgacc
    24901 cctccaccaa agacaatcac gtctgggcgg aaagtcactg tcgcattaac cgcagcttga
    24961 gcgatatagt aggcttgaac atcccaaaca gggttgttga gttcaatagt ttccccacgt
    25021 acacctgtac gagcttccaa acttggacca gctgcataac cttctagaca tcccttatgg
    25081 aaaggacaaa cacccttaaa ctctttttca atatccattg ggtgtctagc aacataataa
    25141 tgacccattt cagggtgacc cacaccaccg ataaactcac cacgttggat gacgcctgca
    25201 ccgatacctg taccgattgt gtagtaaacc aagttttcga tacgaccacc agcattgtta
    25261 cgggcaacca tttcaccgta agcagagctg tttacgtctg ttgtgaagta cattggcacg
    25321 tttagggcgc gacgaagggc accaagcaag tccacatttg cccagtttgg ttttggagtc
    25381 gtcgtgataa agccataagt ttttgagttt ttgtcaatat caatcggccc aaatgaacca
    25441 actgcaagac cagcaaggtt atcgaatttt gagaagaact caatggtttt atcgattgtt
    25501 tcgattggag ttgttgttgg aaattgtgtt ttttctacaa cgttaaagtt ttcatcaccg
    25561 acagcacaga caaactttgt accgcccgct tccaagcttc catataattt tgtcatgata
    25621 aacctcttgt ttttattttc tttattatag catacttcga aagtctaaat gtctctattt
    25681 tttagatttt cctctgtaaa tcttactatc taataaaaac gaacaaacat gtcatttgtt
    25741 cgttttcaca ttagagagga ttgattagat tttcacttcg atcacagcat tccccttcgc
    25801 aactgaacct gttgcgactg gagctactga agcgtagtca gctgtatttg taacgataac
    25861 cattgttgta tcatcaagtc cagctgcagc gattttgttt gagtcaaatg ttccaagaac
    25921 atcgccagct ttcaccttat taccttgagc aacttttgct tcaaaaccgt caccgttcat
    25981 agatacagtg tcaataccaa cgtgaatcaa aacttcagca ccatttcttg ttttcaaacc
    26041 aaaagcgtgc cctgttggaa aggcaattga aacttcagca tcagctggtg catagaccac
    26101 gccttggctt ggtttcacag cgataccttg tcccatagct ccacttgaga agactgggtc
    26161 attgacatca gcaagagcga caacatcacc aacgatagga gttacaagtg tttcattttg
    26221 aagagtatca gtctcttcca ctactggtgc ttctactgta ggttctgtaa ctgtttctgc
    26281 ggttgctgtg gcagcttcat cagcaaagac actagctgct tttgttttcc cgtagaaata
    26341 agtgaaagca aaggcggcaa caaaggacat aatttccgca attatataca tagggattga
    26401 accagcctta atagaaagga atccaataaa tccagccgct cccaatgaaa ctgcaataac
    26461 gtgagttaaa cctgctacaa aggcaccaat tgctgaacca gcaagggcgc agaagaatgg
    26521 gaatttgtat ttcaagttta ccccaaagag agcaggttct gtaataccaa ggaaggcaga
    26581 aacagcagcc gaactggaca atccttttgt tttagcattt tttgtcaaga agtagactgc
    26641 aagagtagcc gcaccttgtg ctacgtttgc cattgaagca acaacaaaga tgtagtctcc
    26701 aaatccagta ccgttattat tgtatgcaga caacaattgt gtttcgattg ctgggaatga
    26761 ttggtgaaga cccgtcataa cgattaatga gtaagttcca ccaaatagcc ccataccaaa
    26821 ggcacctgtt gtgttgtaca accatacaat cgcatttgta atcgcatcag acacaaccaa
    26881 cataacagga ccgataactg taaaggtaag gaatcctgta atcatcactg ataaaagcgg
    26941 tgtaaaagtg aagtcaactg cagatggcaa tttcttgtgg aagaattttt ctaaattagc
    27001 taacaaccag actgcaacaa ggactggaat aacctgataa gcatagtttg tttgtgtaac
    27061 atggaaacct aagatgtccc agaaggcttc tttaccaccc aaatctggag tggtcataat
    27121 cataccgatt gccgcaccaa ggaattggtt tgctccaaag cgcttggctg ctgaaatacc
    27181 aatcaaaaca gggaggaaca taaatggagc agcagacatc aattgaatca tagctgagaa
    27241 gcctttgata gcaggataca tatcttcaat tgattgaggt ccaaacaaat ctggtgatgt
    27301 caagaagttc cgtaaagcca tcaagagacc acctgcaact aaggcaggga taataggaac
    27361 aaaaatgtct gacaaaagtt taatcaagtc catcaatgga ttgaactttt tgtctttatt
    27421 agcaatctct ttcaaatcat ctgtcgaaac ttctttcaaa ccagttttct taataatttc
    27481 cgcatatacg aagttaacat caccaggacc aatgataatt tgatattgtc cgttagtgct
    27541 aaaagtcccc ttgacatccg cattattatc cagagctgct tgattcactt ttgcttcgtc
    27601 tttcaatacc aagcgaagac gtgtcgcaca gtgagctgca gctacaagat tatccttacc
    27661 gacagcctca atgacctcgg cagcaacttt actataatcc atagcaaaaa tctccttata
    27721 taacattttg ttcttgtttg aaagcgattt tattcgccct tacgactatt attttatcat
    27781 gttttaaaaa tatgtcaagc gttttgcaga aaaaatatta tatctactta gtgggcaagc
    27841 tttagattga ttgtttttga ctgtttcatc aggaatttct tgaaaaataa gtttgaaacc
    27901 ttggttaaaa agtcttttat ttcattatct ttcacatttt cgtaaaaatt tgattgattt
    27961 cctgtattta ttttatgata atcgtttgac agttttttct cttttttaac ataaagggct
    28021 tgcatttttt atcgaaaaca gttactatta aaagtgataa gatttttgga ggaatgaatg
    28081 gaatggacaa ctgagcgtcg ttacagactt tatcaagatt ggacgcaaga agaaattcaa
    28141 catataaagg aaaatatggc acaatctcca tggcatactc attaccatgt tgagccaaaa
    28201 acaggacttc tcaacgaccc aaatggcttt tcttactttg atggcaagtg gatcctcttt
    28261 taccagaatt ttccttttgg tgcagcccac ggtttaaaat cttgggcaca gctagaaagt
    28321 gatgatttga ttcactttag agaaactgga gtcaaagttt tgccggatac tccattagat
    28381 agccacggtg cctactctgg ttctgccatg caatttggcg ataacttatt cctattttat
    28441 acaggaaatg ttcgcgatga aaactggatc cgtcacccat accaaatcgg tgctttgatg
    28501 gacaaggagg gtaagattac aaagattgac aagatcttga ttgaccagcc agcagactct
    28561 actgaccact tccgcgatcc acaaattttt aactttaaag gtcaatacta tgctgtcgtc
    28621 ggtggacaga acttggagaa aaaaggcttc gtccgtctct acaaggctgt caataacgac
    28681 tacacaaact ggcaagcagt tggcgacctt gactttgcta acgaccgtac tgcctacatg
    28741 atggaatgtc ctaatctggt ctttgtagag gaacagcctg tccttctcta ctgtccacaa
    28801 ggattggata agaaagttct agactacgat aatatctttc caaatatgta taagattggg
    28861 gcttcctttg accctaaaaa tgccaaaatg gtagatgtgt ctcaacttca aaacatggat
    28921 tacggtttcg aagcctatgc aactcaagcc ttcaacgctc ctgatgggcg tgctctagca
    28981 gttagctggc ttggtttgcc agatgtttct tacccatctg actgttttga tcaccaagga
    29041 accttctctt tggtcaagga actcactatc aaagacgaca agctctacca gtatccagtc
    29101 gctgctatta aggaccttcg tgcttctgaa gaagccttct caaaccgttc ccaaaccaag
    29161 aacacttacg aacttgaact caacttggaa gctaatagcc agagcgagat tgtcttactt
    29221 gctgataaag aaggtaaggg actttcaatc aactttgacc ttgtaaacgg tcaagtgaca
    29281 gtggatcgta gccaggctgg agaacagtat gcccaagaat ttgggacaac tcgttcttgc
    29341 cctatcgaga atcaggctac tactgctaca atcttcatcg ataactctgt ctttgaaatt
    29401 ttcatcaata aaggagaaaa agtattttct ggtcgtgtct tcccacatgc ggaccaaaat
    29461 ggtatcctga tcaaatctgg aaacccaact ggaacttact atgaattaga ttatggtcgc
    29521 aaaactaact gatgtcgcca aacttgcagg cgtcagtcct actaccgttt ctcgggttat
    29581 caataaaaaa gggtatctat ctgagaaaac catccaaaaa gtcaatgaag ccatgagaga
    29641 attgggctat aaacccaaca acctggctcg tagtctgcaa ggaaaatcag ctaagttaat
    29701 cggcttgatt ttccccaata tttccaatgt tttctatgca gaattgattg ataaattgga
    29761 acaccaactc ttcaaaaatg gttacaagac catcatctgc aacagtgaac atgattctga
    29821 gaaggaacgc gaatacatcg aaatgttgga agccaatcag gtagacggca tcatttctgg
    29881 tagtcacaac ctaggaatcg aagactacaa tcgtgtgaca gcgccgatta tttcctttga
    29941 ccgaaaccta tcgccagaca tccctgttgt ctcctctgac aactatgctg gtggggttct
    30001 tgctgcccaa accttggtca agacaggtgc ccagtctatc atcatgatta cagggaatga
    30061 caattccaat tcgccaaccg gactgcgcca cgctggtttt gcatccgtac tcccaaaagc
    30121 tcctattatc aatgtttcca gtgacttttc tcccgtcaga aaagaaatgg aaatcaagaa
    30181 tatcttgacc cgggaaaaac cagatgccat ttttgcttcg gatgatttga cagctattct
    30241 ggtcattaaa atcgctcaag aattgggcat ttctgtccca aaagagctca aggtcatcgg
    30301 ctatgatggg acctacttta tcgaaaatta ctaccctcaa ttggctacta tcaagcaacc
    30361 tttggaagag attgcttgtc tcactattga tcttctcttg caaaagattg aaggcaagga
    30421 agtcgccaca actggttact tcttaccagt tacgctatta ccaggaaaaa gtatttaaac
    30481 acaagaaaac tcagaccgat tcgtctgagt ttttatgatc ttaaattttc gagatagcgc
    30541 tgggctgtct ctaggttaaa ggttttatct gagatgaggc gctctactag gggagcaact
    30601 tcagattcac tagccccagc taggagagct agggatttgg cctgtagttt catgtggcct
    30661 tgctggatgc ccgtacttac caaggctttg agggctgcaa aattttgagc aagaccgatg
    30721 gacacgataa tctgggctaa ttctctggca gaaggatttc ctagtagatc atgactgaga
    30781 gctacacgtg ggttgaggcc gatagagcca cccttagtcg ctacaggcat gggcagggtc
    30841 atctcaccga ccaattcttc tctttcaagg tccagcgtcc agcagctaag accttgatag
    30901 cgtccatctc gactggcaaa ggcatgggcc ccagcttcga tggcacgcca gtcattacca
    30961 gtggcaatca aaatcgcatc aataccatta aaaattcctt tattatgagt agcagctcgg
    31021 taaggatcag cctgcgcaaa ctgactagcc aacgcaattt tctccgcaat ctctcgtcct
    31081 tgatcctttt ggcggctcaa gtagcgaaag gcgatgcgac agcttgcagt caccagagaa
    31141 tcagtcgcgt agttggacag gattcccatg agactctgtc cctgactgag ttcttctaag
    31201 actggtttca aggcttccag catggtgttg agcatattgg cacccatggc ttcctgggta
    31261 tcgacatgaa tataaacaac gagaaagtct ggttcgcctt ttatctgctc gacatgcaga
    31321 tcacgcgccc cacctccacg tttaacgata gaaggatagg cttgattggc aagctccaag
    31381 agctccgctt tcttgctggc aatcttctct tgcgctagtt taggattagc aacttgataa
    31441 agggctacct gcccaatcat ctgtcgctga tggacttgtg cagtaaaacc acctgcacgc
    31501 ttgatgattt tgctggcata gctggccgcc gcaaccacag agggttcttc tgtcacgtag
    31561 ggaacggtgt attcctgacc gttgacaagt acctctggaa ccagtgaata aggcagagaa
    31621 aaagttccca ctacattctc actcagctgg tctgccacag tcacgctcat ctgttcatcc
    31681 ttctccagac tagcttgtct ctcaggacta aggagcgcct gagcttttaa cagctcgagg
    31741 cgctcttggt atgatttttt agaaaatcca ttccaactta tcttcattat ttttcaacct
    31801 tgctataacg gcgttggtgg tcgagaattt caaccaaggc aaaatcttga ttttcatagc
    31861 cagcaaactg ggcagagttt gtttcatcca agtttacttc ctcaaaaaag accttttcat
    31921 agtctgcaac ggatagggca gttcgttggt tgagcttgtt caaacggtct ttattcaaat
    31981 aagcttcata tccttcaacc aattcaccac tgaagaactc agccacagct ccacttccgt
    32041 aactataaag ggcgatttta tccccagctt tcaagctatc tgtattttcc aagagagaca
    32101 aaagtccaag gaaaagtgaa cctgtgtaga tattccccac cttttgactg tagagaatag
    32161 actggtcaaa atgcttttgt aagaggtctt ttttctcttg aggcaggctc ttatccatga
    32221 tttttttcaa gccttttagc gctaatttag gataaggcaa gtggaaacaa acagccgcaa
    32281 aatcatccaa agtaagctgg tagcgttttt gatattcaag ccaagtcgtt ttcaaactat
    32341 ccaagtattg ttgggtagaa tagacaccat ttacataagg agttgtcgag taatttggtc
    32401 gccagaaatc catgatgtca cgggtctgag ctacattgtc attattaaag gccatcatgc
    32461 gtggattttg tgtaatcaac atagctacac ttccagcacc ttgagttggt tctcccggag
    32521 tttcaatacc atatttggca atatcactgg caatgaccaa taccttggac tccggagaat
    32581 tttccacatg caatttggca taatggaggg cagctgtcgc cccatagcag gcttctttaa
    32641 tctcgaaact acgagcaaag ggctggatgc ccagcaagcc atgcacaaag acggccgcag
    32701 ccttactctg gtcaattcct gactcggtag ccacaatgac catgtcaact tcttgtcttt
    32761 cttgctcagt taaaatagag tcactagcac tggccgccaa ggtcacgatg tcctcagtta
    32821 ggggcgcaat actcaattcc ttgagtaaga gtcctttact taatttttca gggtcaattc
    32881 ccctcgcttc tgctaagtct tgtaatttca agacatattg actggtcgca aaaccaatct
    32941 tatcaatacc gattgtcata tttacctctg ttttatcatt catgtaaaaa atcgttctat
    33001 actattttat cacaaatggc agtaaaagag agaaaaaaga cttgattcac caaatcaagc
    33061 ctcttattgg tcatcatttt aaagaatgat tagttgctag agagttcacc gatataagta
    33121 gctttataag ctccattcac agttatcagc tcctggagga tcaaatttcc tgagtaaatc
    33181 cttcccatct catctacaaa tttttgataa aactgactgg tcggaatttc tctgacatcc
    33241 ttatcaaatg tcttgtcaag tgttttacta accttctcag caatcaattg atgctcttgc
    33301 catccacttt gaaactctga gcccgaacta gaaaccatga ctgggataaa caacaaggtc
    33361 agtagattta cagacaataa ggaaagtagt agacttcctg caaaactaga atcctagttc
    33421 atgattgata atgccagcaa tcaaattcat tcgtaatccg aagcgtttac gatgatttcg
    33481 ataggttgtt gaaaacattt taaacgtttt tactttggca aagatgttct caaccttgct
    33541 tctctcctta gatagcgcat ggttataggc tttatcttca actgttagcg gcttgagttt
    33601 gctggattta cgtggagttt gtgcttgagg atatatcttc atgagccctt gataaccact
    33661 gtcagccaag attttaccag cttgtccgat atttctgcga ctcattttga acaacttcat
    33721 atcatgacaa tagttcacag cgatatccaa agaaacaatt ctcccttgac ttgtgacaat
    33781 cgcttgagcc ttcatagcgt ggcatttttt ttaccagaat cattcgctaa ttgttttttt
    33841 tagggcgatt gatttttact tccgtcgcat caatcattac cgtgtcttca gaactgagag
    33901 gagttcttga aatcgtaaca ccacctttga acaagagtta cttcaaccca ttggctccga
    33961 cggagtaagt tgctttcgtg gataccaaaa tcagccgcaa tttcttcata agtgcggtat
    34021 tctcgcacat atagaaagcg ttgttaattt atttatctca tttttcagaa aattctttta
    34081 tttctgtaaa gtctacgata ctcgatgtgt ttttatataa tgatacagtc tgagaatcac
    34141 tgttccgcta gccattccaa tagagattac caaagccaac atgacaacca aggtcgcact
    34201 tgccagtgct ttattatagt cccctgtcac aaaaaaggca gttgttcggt aggagagata
    34261 acctggaacc agcggtgcca aaatggccaa gataaagacc acagcaggtg tcttataaag
    34321 aatacttaaa atctggctga cacaagaacc aataatggct gcaatgaagg tagctacaat
    34381 gacattggtc ggttccttga gcaagagata gattagccag acagtcatgc ccaaaatccc
    34441 tccaggtaag agcatagacc gttgcacatt gagtacgatt aaaaaagtga taatggcaag
    34501 aaaacttgct actgcttgta ataaaaaggt tgttagtgtc atattagttc atcaatacca
    34561 aggcgacaga agttcctgcc cctaaagcga gggtaatgag cagggattca aacatcttac
    34621 tcataccaga gtttatgtgg ttggtcataa tatcacggac cgcattggtc aaggcaatac
    34681 ctggtacaaa cggcatgacc gcaccagcta taatcaaatc tgccgttgaa ggaaaacctg
    34741 tgtagcgagc ccaaaactgg gcaattatcc caaagacaaa ggctccagca aaggctgtca
    34801 caaagggaat tcggataaat ttttccacat agagggaaaa ggcaaaacca aataaggtcg
    34861 ccactcctgc cccaagtgcg tcgtagatat ttccgctaaa cataactgaa aagaaaggag
    34921 cactaaaggt cgcagccaga gttacctgca acttagtata gggaaggggt tgagcttgca
    34981 aggccgtcaa ttgcttaaag gctgtttcta agtcaatctg ccccccaact agctgacgag
    35041 aaatctggtt cacatcgcag actttttcga tgttataaga agaggaggtc acgcgcttca
    35101 tgcgcgaaat attggtattt tcaatagaga aaaagatagc ggcaggcatg gcaaggacat
    35161 tgcaatccac aatcccctgc gaatgcgcga ttcgaatcat ggtatcttct acacgatgga
    35221 tttctgagcc acttttaagg agaatagtcc ccgctagcat aatcacatca atgacggcat
    35281 ttaattcttt tgattcttcc atgctttcct ccttttatca actccctcta ttctatcaca
    35341 aatctggact caaaaaaaaa tctttgccat gaaatcatga caaagattga ttactcattt
    35401 tgattatcca tctgctttta aggagtagct gaagttgttt taggtttgta gattgaaatc
    35461 ttgactctag tcttatttag gtctaccttt tcacctgctc taggactttg ttcaacaacc
    35521 atgccttcta cactacctgc aggcgctgtc gtcacttcta caacttctat attagcttcc
    35581 ttaatcccaa caatttgaat caaattgttc ttagtaaact ccaagctgga accaatgtaa
    35641 ctcggcatgg caacacttgt aactttttta gctactgtca agacaatttg agtaggttta
    35701 ctcacatcat aagtcgttcc ggcacctgga ctttgtttca taatcgttcc tggttcgctt
    35761 tcgctggact cttcttcctc tatcttaatc aaattctcag gaaccttctt ctgcttgagt
    35821 tctgagatta cttctgtaga gttccgtcca atatagttcc ctaattgaat cgtcgtagct
    35881 tttttagcta ctgtcaaaac aatttgagtt gccttactca agtcataggt cgtaccttct
    35941 ggtagacttt gcttcaggac cgttccagcc tcactctcat tcgactcttc ttcctcaatt
    36001 ttaatcaaat tatctggaac ttttttctct tttaattccg cgataacatc agaagatttc
    36061 cggccgacat aattactaat ttggaaggat tgtttgcctg atgagacaac cagattgatt
    36121 ttcgttcctt cttttcgacc agttccagcg ccaggatctg tacggataat ccgcccttct
    36181 tccacctttt cactagcctc tgtcttctcc tcaccaatct caaaattggc ttttttgagc
    36241 gttgccttgg cctctgcaac tgtctgacct gccacatctg gaatggcaat ggttgcagga
    36301 gttctggata gtatccaaat aagagaagct gccaccaata caaggctggc caacaaaatc
    36361 aggtaacgca tcttaaatct atgttttttc ggtgcttgtg gttggtaagt ttcctctgtc
    36421 acagcctggc ttgggttttt gattgatttg tgttctgtct gcgcttgaac cttaggaata
    36481 gatgtcaagg tactctgaga aaccttcggc aaggtcttgg tatctgcctt gctcgtttca
    36541 tcaaagatta acttactttc atttctacga ttgtaggaca agctactaga caagtccaca
    36601 tacatctctg aaaccgagcg gtagcgattg gtcaactttt tagcagttgc cttgataata
    36661 acattttcta aagcctgagg tacagatgga ttttctgcaa taacggacgg caggggtttc
    36721 tggaaatgct ggagggcaat ggtcaccgcg ctatccccgt cataagggat atggcctgtc
    36781 aacatctcat agaaaataat ccccatggca tagatatcac tctgcacagt cgccttcgaa
    36841 ccacgcgcct gctctggtga caagtaatga actgagccca acatcgagtt agtctgggtc
    36901 agacttgtct ctgcaaaggc tacagcaatc ccaaagtctg tgaccttggc cgtcccatct
    36961 ggtgtcaaaa ggatattttg aggtttcaag tccctgtgaa caattcctcg agtatgggcc
    37021 aagcgcatag ccaagagaat ttgtcccatg atacggactg cttcttcatt agaaagagga
    37081 taatgttcct tgatatagcg tttgaggtct agtccagcaa catactccat tgcaagatac
    37141 tgttgaccgt cttcctcacc aatatctgtt atccgaacga tatgaggatg gtctagatct
    37201 gccatagctc tcgcttcacg ctgaaaacga gctacagcta tcgggtccgt ctggtagttg
    37261 gtcctcagaa ccttcactgc cacttcttcc ccatctaaga ttaagtcttt ggctaggtag
    37321 acatccgcca tgcctcctcg accaatctgt ttgacaatcc gatagcgtcc ggcaaaaatc
    37381 ttgccgattt ggatcattct tcatcctcct cgttcataga aacaagggca accgtaatgt
    37441 tgtctaaacc tcctgcattg ttagcaaaac gaacaagtgt ctccgtttta tctgctaaag
    37501 gaatatcact ggttacaata tcacgaatct cactgcctga aatcatgttg gtcaagccgt
    37561 cactattgag caagagatag tcacctgact caaggataac tgtcccaaaa tcaggctgaa
    37621 tttcatcttt ttgcccaata gactgggtga taatattttt ttgcggatga gcttctgcct
    37681 cttctggtgt caattgacca gccttgagca attcattaac caaggaatga tcgctcgtca
    37741 actgatggta ttcttctcca cgaatcaagc cgatacgcga atcaccaata tgagcataga
    37801 tagcctgatt atcaataata gcaaggactt ccaaagtagt tcccatacct ctgtaagctt
    37861 catcctgacc aagctggtga atcttttgat tttcaatttc taggtaatgg gcgaaccatt
    37921 cacgcacttc attgactgta tcgatctggg tatcaaccca agctacaccc aggtctgtga
    37981 ccgccatttc actagcgata ttccctgcac gatgacctcc catcccatca gctaaaataa
    38041 tcatggtacg tccagctcta ttgacatagt ggttgacata gtcttggtta tttgttcgtt
    38101 tctgaccaac atctgttaat aatgaaattt ccatgtgtca gttccttcct aatccgatat
    38161 cttgcgaaat tgactgatga agaatccatc acttccatac aattcaggtg taatgaggat
    38221 acagccgtct ttcatgatat ccttacattc atgttctagt tttacctgct cgaactcggg
    38281 atgactctct aaaaaggcct taacgacttg aaaattctcc tctgagacga tagtgcaggt
    38341 gctataagtt attataccac ctttgcctag tatttgacaa acactaccta atatttctaa
    38401 ctgaatttcc tgcaaggacg cgaaatctgc cgtttcttta ttgtatttga tatctggttt
    38461 tcggcgcaaa agaccgattc ctgaacaagg agcatccacc aaaatcttat caaaggaatc
    38521 ctggtcaaaa aactcatgca cctttctggc atctaatttt tgagtttgaa cccgatctgc
    38581 aactcccaga cgttgggcat tttcttggat taaatccaac ttgtggtcgt acaagtccag
    38641 agcagtaacc tgacctgtcg taagataaga ggctatatgg gctgttttcc cacctggagc
    38701 cgcacaggca tcaagcactc gctcatcacc ttgtaaatca agcgtcggag caaccagctg
    38761 actggactcg tcttggatgg taatggctcc attcgtaaac aaattatgcc ctgcaaaatg
    38821 cccttgctcc ttaaccagac cagtggttgc taaaagggaa ttattcgcct ccaacaaggc
    38881 ttggatttcc tcttttcgac ttaggtctgt tacacgaata ctggctttgt ttcgcactaa
    38941 caggctttca aagatggctt ttgctctctc ctctccgtat tcttccttga gtttggcaac
    39001 tagccaaact gggagagaat aggcaatgga gtcacgcttg ttttttcgct tgatgctagc
    39061 aatatctggc cagccttcac gcaagatacg gcgaaggaca gcgttgacca atttttcact
    39121 gcctttttta cggagtttgg ccaattccac tgcttcattg accacagcat gatctggaat
    39181 cttgtccaaa tagcggagtt ggtaggcact catgagaaga aggacataga gccagctgtc
    39241 taactggtct ctgtcttcga taaagtggga taggtaccat tccagagtca gtttacgggc
    39301 taccgttcca tagaccagct cggtcactaa gcccttgtct gctgcagaga gctgactccc
    39361 cttgaggtgt ttatttaagg caatatttga atatgcttga ttcacaaaaa catcctctag
    39421 cactgctaga gctaaacttc tagccgtttc tactttagtc accaaatcgt tctcctacag
    39481 tcaatgtacg tccaactccg ttgaggaagg aagcaatgtc catcttaggc ttaccagctg
    39541 gctgcacttg tttgagggat agagcccctt cagccgttgc gacaatcaat tctttcttgc
    39601 cgatagagag aatctcacct ggatttccct gaccttctac tggtagggct tcataaatct
    39661 taaagcggtc acccttaagg aaagtatggg caacaggcca ggggttcatt ccacgaattt
    39721 ggttaaagag ttgacgattg gttttgttcc agttcagttt ttcttcctct gactttatat
    39781 ttggagagaa ggtaacctga ctcgtatcct gcggttcagg tttgatatca ccagcaatat
    39841 aggcaggcag agtgtccaaa agcaaatcac gaccaactag cgccaatttt tcaaacaagg
    39901 tgccaacatt gtcctcatct gtgatcggaa tgctgcgacg agaaatcata tctcctgcat
    39961 ccatttcctt aaccatttcc atgatggtca caccagcttc ctcatcccct tgaatcaagg
    40021 cataatggat aggcgcacca ccacggtgtc taggaaggag ggaggcatga acgttgacag
    40081 caaagtccat gctatcaagg agtttgcttg ggagaaactg cccaaaagca gcagtcacaa
    40141 ttccatctgc tcctagcttc ataagatctt ccatctctgg acttccagat aatttttcag
    40201 gttgatagat agataatcct gcttccttgg cagcctgctt gactggggtt tcttggataa
    40261 cttttttacg accaacagca cggtctggct gggtcacaac ggctagaatt tcgtaacggt
    40321 catctgtcaa aagtcctttt aagactgttg ctgaaaagtc gggggtcccc ataaagatta
    40381 gttttgtcat atcttctcct tcttataaaa attgctgcgg ctcatggtca atgctgagac
    40441 ggagctcact attttcccgt tcttgagtca aggccaggac ctggttgagg gtcggcccca
    40501 gctcatcttc taaacggtat ttaattaaaa tctggtaatg atagaggttg tgggtacggg
    40561 caatcggttt tggcgttggc cccagaatgg gactggtctc tgacaagcct gaccgcaaaa
    40621 tgttcatgac ttcataggca cgtttgaaaa cctcttcttc tttcttgtga gaaagggtaa
    40681 taccaatcgt gaaatagtaa ggtggatagc cgagttgtcg tctgattccc atttcatagg
    40741 cataaaagcc ttcgtaatct tgatccttgg caaatcgaat agcatagtgc tgcggattgt
    40801 aggactgtat caagacttga cctgcttttt cagcccgacc tgctcgacct gccacctgag
    40861 tcaagagctg gaaggttctc tcagaagaac ggaaatcagg cagattcaag gccgtatccg
    40921 catttagaac tccgactagg gtaacattgg gaaaatccaa accctttgca atcatctgag
    40981 taccaagtaa aatatccgct tcccctcgcc caaactggtc aagcaaggct tggtgactgc
    41041 ctttctttcg agtcgtatcc acatccatcc tcaaaatgcg agcttgggga aagagttctg
    41101 ctagctcatc ataagccttc tgagttcccg tcccatagta acgaatactg tggctcttac
    41161 agttaggaca gacctgagga atatccttcg agaaaccaca ataatggcag ttcatagtct
    41221 tggtatccat atgcaaggtc agagaaatat cgcagttggg acaagtatcc accgtcccac
    41281 actcccgaca catgacaaag ctagaataac cacggcgatt gagcatgaga accatctgct
    41341 cttttttaac cagacggtct tggatagcct ctagcaaagg aggcgtaaag tttgacgtct
    41401 cattttgtcc gatatagtct cgaaagtcaa tcacttgaac ctcagggatt gtagccaaag
    41461 gattggcacg ttgggttaga cgtaagtgtt gatagacgcc tttgccagca cgtgcccggc
    41521 tctctaagct cggcgttgca gatccaagta ccagagttgc ttgattatac tgagcccgta
    41581 aaatagctac ctctctggca tggtaacggg gattgctgtc ctgcttataa gccgcttcat
    41641 gctcttcatc aataatcatg acacccagat ttttcagagg agcaaagata gcagatctgg
    41701 caccaacaac aacttgggca tcgccacgct ccaccttgcg ccattcatca tacttttcac
    41761 cattggataa tcctgagtga agaatggcta ccttgtcccc aaaacgtgct ataaaacgct
    41821 cggtcatctg aggagtcaag gaaatctcag gtaccagcaa aatagctgtc ttgcccttat
    41881 ccagggcacc ttggataatc tgcaagtaaa cctcggtctt cccacttcct gtaatccctt
    41941 gaagtagaaa gggaggttga gaactgccaa tagaactcac aaccgcatca cgcgcctgtc
    42001 tttgttctgg atttaactcc aaaggtctac ttgcttcaat tccttcaaaa taagcagccg
    42061 atcgtcgaac ttccttttgg actatagtaa cagcaccttg atccacaaag aagttaactt
    42121 gctctcgcga gtaggactct aacaagctag ccaaggaagc gctctctgga tgagacagca
    42181 gataatctct cagttccaac tttttcttgg cacgtgtaga aatctcaaca ccttctaatt
    42241 gagcatggtc aacctcatac caagactggg tcttgacctt cttttgatcg actgcctgat
    42301 attccagacc aagcaggcct tttctagtca aacgcatcat ttcagcttgc ttacctaaat
    42361 ccagagaaga aaaggctagc gaatcttctg aatcaaacag gcgtactcgt tcttcctgac
    42421 tcaagccttc cagaggatag agaatcttgt catagctaga attcagaaat cccggaagca
    42481 tggccttgag gatagagatt ttgtaggaga agacagattt gcgtaactcc tcagccagcc
    42541 agagttgttc tggcgtgaga acaggagaaa aatccagcac ctctgcaata tcttttaaat
    42601 cttgctccat ctcttctcca tctgattggg actccaaacc aagaacaatc ccttgaatca
    42661 ggcgattacc cttaccaaaa ggcacatgaa cccgcatccc aacttccagc attccctcaa
    42721 attcctccgg aatcctgtaa ctatagggct ggtccgtctg catcaagggc acatctacga
    42781 taatcttagc tagggccatc ttctcacctc ctccttgtca gtacattctt gcaatagaaa
    42841 aaataagatt gagtcccccc aaccttaaat tttttcacca tcttcttttt ctttagcaat
    42901 ttgctctttg attttctttt cttcttcttc tttgcggcgt ttttcttctt cgatacggcg
    42961 acgcactgct tcacgttttc cttctggatc tgggtgaatt gtaacgtttc ctgattcgat
    43021 ttcttctaaa gcgcgaagag ttgatttttc agacttgaaa ccttgagttg ctggggcacc
    43081 tgcttccaat tcgtgggcac gttttgcttc caagattacg agtgaatatt ttgaaggaac
    43141 cttgtcgagc aaggtatcaa tagagggttt taacatcatt tgcttgtacc tattttctaa
    43201 attttatcgg gtagttggag attttggtaa catctcctga tagtgaccaa tgacacgatc
    43261 cacacagaag tgttctgctt caatcacaca tttgacacgt tcagcagcta ggggcacctg
    43321 atcgttgaca atcgcataat catactcacg catgagggca atttcttcct tggccttttc
    43381 gattcgttgg gcaatcactt ctgcactatc tgttccacga cctaccaagc gatcttgcaa
    43441 ttcatccaaa tctggtggtg tcaggaagat aaagacagca tctggaacct ttttcttgac
    43501 ctgaagagca ccctgaactt caatttcaag gaaaacatcg attcccttgt ccaaggtttc
    43561 attgacatag gtcagaggag ttccatagta gttgccgaca tattctgcgt attccaacat
    43621 ctgtccttga cgaatcagct cttcaaattc ttcacgagta cggaagaaat agtcaacacc
    43681 gtccacttct ccaggacgtt gtgcgcgtgt cgtcatcgat acagaatatt gaaattggtt
    43741 ttcagaactc tcaaaaatct ctcttctaac cgttcctttt ccaacccctg aaggaccaga
    43801 aaaaacgatt agtaagcctc ggtctgccat tgtgtctcct tttagtcaat ctgtgaaata
    43861 acatttctct agaataatgg caaaaagcca gattatcctt tacagtcttt ctatctagtg
    43921 taacaaaaaa gcagtaattt ttcaactgct ctttcttatt tatttagcat aatctactgc
    43981 acgaagctcg cgaatcacgg ttaccttgat atttcctgga taatcgagat tgttttcaat
    44041 tttcttacga actttgtgag ccaagattgt gactttgtcg tccttgattt ttcctggatt
    44101 gaccatgata cgaatttcac gtcctgcttg aagggcaaag ctagtttgca ctccttcaaa
    44161 gccgttagca atttcttcca aatcatggag acgcttgatg tagctttcaa gagactcact
    44221 acgagcacct ggacaggctg cgctcaaggc atctgctgca gcgacgataa ctgctatcac
    44281 gctctcagct tcaacatctc cgtggtgact agcaatcgta ttcaccacaa ctgggggttc
    44341 cttgtactta cgggccaatt ccataccgat ttcaacgtgg ctaccttcaa cctcatggtc
    44401 aatggctttc ccgatatcgt gaaggaatcc agcacgacgg gcaagagccg cattttcacc
    44461 aagttcgctc gccatgatac cagccaactt agcaacctca atcgaatggc gcaaaacatt
    44521 ttgtccatat gaagtacgga actgcaaacg tcccataatc ttcatcaagt ctggatgaag
    44581 gtttggcgca ccaatttcat aggcagcagc ctcaccgtat tcacgaatct tattgtcaat
    44641 ctcttgacgg tttttctcaa ccaactcttc gatacgagct ggatgtatac gaccatcttt
    44701 gagcaacatt tccatagtca tacgggcaat ctcacgacga atcggatcaa atcctgacaa
    44761 ggtcaccact tctggtgtat cgtcgataat cacatcgacc cctgtcaaac tttcaaaggt
    44821 acgaatgtta cgaccttcac gaccaataat gcgtcccttc atagtatcgt ctggcagatg
    44881 aactgttgag tttgttgact ccgctacata ttcaccagcg atacgttgca tagcttgaac
    44941 caagatgtcc ttggccattt tgtcagaacg ttccttgacc tcttgctcag cttcgcgaat
    45001 gcgactggca atctccctgg tcaagttttc ctctgtctga gccaagataa tatctcgtgc
    45061 ttctgcctga gacagagcac caatacgctc tagttctgct tctttttgtc tttcgacttc
    45121 ctctaattgc tcttcacgcg catcaaggtt tttcgctcta tcagaaatac tttgttcttt
    45181 ttgttcaagt gtttgttctt tactcgtcaa attgtcgtcc ttacggtcaa ggctagtagc
    45241 tctctctgtc aaacgacttt cgatttgttt gagttcttga cgttctgatt tgaattcagc
    45301 gtccacttct tcacggtatt ttctggcttc ttctttggcc tccaatagtg cttctttttt
    45361 aagagacttg ctttcacgtt tggcttcatt aacaagtaaa tccgcttcac gctcagcttg
    45421 tccacgtaaa ttagttgctt cttgttcagc atttaaaagc atcaactctg cagcttcctg
    45481 agatgatttc atcttagctg agatgctgac atatccaatg actaaaccaa tgatgacggc
    45541 aaaaacagca atcgcaagcg acatgatttc catgttttta cctcatttta ttgttattcc
    45601 gaatgacata cattctttta cattctacca taaaaaagtg attttcacaa acctaaaata
    45661 gaatatgttt tggggaattt ggaacacatt tgccaaaata aacttgtttt ttagaaatag
    45721 tagtttagta gagacttgag aaaaagccta cctttcaata gacttagtaa tgatctttaa
    45781 aggacaagaa agccacgcta tctccatcca tcatataaat caagcgattt tctgcatcaa
    45841 tacgccgtga ccaggctcct tggtaatcat atttgagtgg ctctggtttt cctattcctg
    45901 taaatggatc gcgttgaata tccttgatta atttattgat tctttttagt gtttttttat
    45961 cttggttttg ccagtagcaa taatctgccc acgcatcttc tgtaaacttg agtagcattc
    46021 atcactcctc aatcacatgg acctgaatgc ttccagcacg gacttgagcc attcctcgca
    46081 aaaccttgtc tgataactcc ttattttgag cgattctcag ggtttcctga atactgtccc
    46141 attcgctctt tgaaagaact acaatgtcct catctggatt tttattgacc accgtcaaag
    46201 gctcaaattc atcatttacc ttcttcatgt agtcctttaa atgatttcgg aatgttgagt
    46261 aaaggactgc ttccataacc atacctcgtt ttagctcttt tccactatta tacacgaaaa
    46321 gaaagaaatt gtcaggaact tgtacaagat tttcttttct atctatttat actcaatgaa
    46381 aatcaaagag caaactagga aactagccgc aggctgtact tgagtacggc aaggcgacgt
    46441 tgacgcgatt tgaatttgat tttcgaagag tattattcgt aaaaaatctc aaaaagccta
    46501 cctttcggta gacttagctt gtttctattc taatcggcac tcttccaaaa ttttgctctg
    46561 ctatacttgg ctttcctagt tggtaaatct ggtctgcttt ttgggtcata gcatcccaag
    46621 gttctttgcc aattcggctg actagattga cctgtccttt cagagacttg agatgttgcc
    46681 tgcctttttc agtaaatcca aggacatgaa tggcttctgg caagacattt tctctagcct
    46741 gcaccaaaat ataggtcaat aggcgtctga cacgcgcctt ggtgtaacgt ttggtcgcaa
    46801 ccgcctcgac caactcttct acagactggg ctgttttaat agcttcttta atgcgcacag
    46861 ccatttcttg attgacctga tagatggtgg ttaggtcggg atttgacaag atttgatagc
    46921 ggagcaaggg aaaatagtct tcccagatca ccttactggc ctgctcaaat agggcaacag
    46981 aaggcataaa gcgttctaag aaatcttggt ccttctgatg ttgacggagg gctgtcgccg
    47041 aggcaaagtc cacatcttta ttcacagaat ggtaacctgc cccctgacgc tgaatcgtat
    47101 gcagcttgat atttcgtcct gcaaccgcct ttgcataggc cagagcaaga acatgattgg
    47161 gggtattacc tgaaaaatca agaccagcaa attccttcca catagattgg gttttctggg
    47221 gataggaaag ggaatcaggc agattttcca caaatttctc catctcagca cctttctctg
    47281 tgtataagtc agcgattttc tgataatctc gaacttcctc tgtcccaaaa actagactat
    47341 caatgcccaa gcgatccaag atatccacag ctccttgacc aaagaaatca gctgcctgaa
    47401 cactgactaa aaagggcaat tccactacca agtctgcgcc attttccagc gccatctggg
    47461 cccttgtcca cttatccaca atagcaggct ctccacgctg catgaaattc cctgacatgg
    47521 caacaatttt cagtccctct gcctgatcca gcaggtattt atggccatta tgaaaaggat
    47581 tgaactctgc gataatacct gtgatggtca tgatgttctc ctacttctgc gccacaaaaa
    47641 accaacgggt gctagtttct gttggttcct tatcctcaaa gtctgcatag agtttgaagg
    47701 acttgaatcc agcctgttcc agcaagatat cataggtcaa gatctcataa gtcctctcct
    47761 catgtacttc atcgtggcga ctaaaggaac cgtcagcctc cttgataaag aaagtcagct
    47821 catgcacgat ggagtgagga gcttcgtcct catatgtatc ccaaagcatg gcaaaatctt
    47881 ccgcattttc atggtaggaa tagccaggga atacttcatc tgtctggtag gtcgagtgca
    47941 cgtcaaagat gaaaactccc tcttcattca gcgcattgta cacgtcctta aagacgtccc
    48001 ctacttccac ctcatcctgc atatagcaga tagagtccga ataacacgtg acaaaatcgt
    48061 atttccctgc cttggacaaa ttcagcatat taccttctat aaaagcaatc ttttgcttgg
    48121 ctgaagttgc tctcttctcc gcaatcttca acatatccgc actcaagtca agtccagtca
    48181 catcaaaacc agcctgagag aagcgcactg attgaattcc tgtcccacaa gccaattcca
    48241 agagtttctt tctctccttg gtcttaggca aatgacgcag agaaaaattc gtccatttgt
    48301 cgtataaact atcgtccatg accgcatcat agaccgccgc aaaggtttca taagtcgcca
    48361 taatcatgat actaagagct ccatggtaaa caccactagc cctttacctt tctatcaatt
    48421 tttctaaaat aagcaaagaa acccagttga ctacaactga gttcatcttc taagcaagag
    48481 cttctgaaat atctactgaa ttcgcctcat gccatagctt ctctagatta taatgggcac
    48541 gcatttcttc tgaaaagata tgcacgacaa cagcaccgag gtccagtaag acccagcctc
    48601 cagctgcatc gccttcgaca tggctacctt taaagcctgc ttgagctact ttttcacgga
    48661 tattagctgc gatagcgtcc aactgacggc tattcattga gctagtgatg acaaagtagt
    48721 ccgtcacact agtcaaatct tgtacatcaa gtgcgaggat atcctccgca cgtttctcat
    48781 cagccgcttt cacgactagt tctagtaatt ctttttcgtt catttaatcc tctttttaga
    48841 aaatatgttt gtaatctaga acatctgcaa agcgctcctc ccaaatgtcc tcataaaatt
    48901 cattaatcgt ttctgctgga atgtcatccc catcaaaggt tgtgacagca ccttctggaa
    48961 caataagctg atagccatat tcaaaggcaa ccttgacaga ggtatccaca caatattctg
    49021 tctgcatacc acataaaact aatttttcaa tcccctgctt atccaagtat tcttttaagc
    49081 cagtttcttt gaaaatactg ttatacttct tctgaaagac cttttcagca ggttttcgat
    49141 ttaaaagcgc agataactgc caatcttctg atgtttgagc ttcagagttc tcaatatgtt
    49201 gaacatagat aatttcaata ttcttgcttc tagcctggtt ttgtaaataa gaaatttttt
    49261 ccaatagact ttttgtctgg aacccagttt ctactaaaac attctgaaca tcaatgatta
    49321 taaaagccgt cttcatttag tcctctttca aatagtgcac aaaggcgtta taggtttcaa
    49381 gggtttgggg atagatgggg aatccctgat gagctagata ctccacggta cgagctgttt
    49441 cgtaggccac cgccttattg agcgatagac ttgcaatctc acgcgccaca tccactccag
    49501 gaaatgcccg attgtgctcg atatagtctg cgacgtagat gaccttatct aggtctgtca
    49561 tttgaccagc tccgactgta tgaatttcaa tggctcgcag aatttcagaa tcatgcaaat
    49621 ccaaatcttc ctgaattttg taaattccga ccataccatg ccagacatta ttaccccagt
    49681 ttttgaggtc gaaatctagc tgataacggt caatcaagtc tagaaattcc tgatctgaca
    49741 actttttagc atagtcatga agaagacctg ctagacttgc tttctcaaca tctacaccaa
    49801 agcgctgagc taattccata gcggcacgct ccacacctag acaatgggtt agacgtttct
    49861 caggtagaag ctctgccatt ttttccaaca aggcctcacg ggagcagttg atatagtctt
    49921 gataggacat cagtagagcc cctccttctc gatgtagtct agcactggct gaggtaggag
    49981 aaagttgggt ttccgacctt gggcaatgaa gtcccgcacc atgctggacg agatatccat
    50041 gagcggtacg tccacccaga taactggata ggaagtccct gccttgtagc gtggacgctg
    50101 aacccccaca aactgaacca tgtcaaccag ttcatcaatt cggtaccact taggcagata
    50161 gtcaaccatg tcggcaccga tgataaagta ataatccgta tctggattct tctctgtcaa
    50221 aatcttcatg gtgtcgtagg tgtaggaaat acccttgcgc tccaactcaa tggtttcaat
    50281 gactaggccg tcaattccct caattgccaa ctcaagcatc ttgagacgat ggtgttcagg
    50341 gatggtttcc tttttatcaa cgtgaggagg ttggtattca ggcatgagaa gaacttgatc
    50401 cagtcccaac tgttgccgta cttgatccgc aacaatgaga tgggcattgt gaacagggtt
    50461 aaaattcccc cctaaaatcc caacttgttt gcgttttttc tccttgattt ctggctccaa
    50521 ctctaccttg gtaaagggag tcaatagttc gattgtcata ggctagtccc ctttatttct
    50581 ctataaaaac agttatttgg agtttcggtc ttagatttct ttgactttct tagaaatctt
    50641 gcgattttct ttcttgctag attgtttaaa caaaatcaag atgcgtccta ttttttggac
    50701 tgtatccaca ccgatttctt cttccaaaat ttcagctact tcgtggatgt tttcatctgt
    50761 gttttgtaag agagtaacct tgattaattc acgcgcatca agagcttgac ggacgctggt
    50821 tttgatttgg tcgttgagtc catttttccc gatttggatg ataggtttga gggtgtgtgc
    50881 ctggctgttg aggaaggcac gttgttttga tgttaatgac ataatttctt taaaagagtt
    50941 tctttttata cttttctgaa gtggtgacgg acgtcagcaa agtccttcgg actttcatga
    51001 ctaaaatttg agcctaaggt ctcaaatttt ccgcagttgg tacaatcact tgtaccaact
    51061 tacaccacag cgaaaagtat tctctatggg gctcgccttg ctcgcccaaa ttcagacaac
    51121 cctttccttt ctgtgcttaa ataattgctt ttcgtgtgac gacggcgacg ccttctggtg
    51181 cccagacggc gacttttgct atgcctgtta cacgaatcca gcctaggcct gaaatgacta
    51241 ggtctgtctt atctttaatg gtaaagacat gctggactag ccttgggaaa tcttcttttt
    51301 ccttgctatt tggtggtgtc agaagagttc ccaggtgctt atcgtagaaa gcactagctc
    51361 cttcaagctt gctacgatgg agtttgagtt cattatcaaa gaaagcagta aatccttgct
    51421 tttctcctgc tataaagtca aagcgtccca aaccacctaa aaatagggtt tgctcaggat
    51481 taagctgata ggtcttaggc ttgatttcct ttttaggact gacatacttg aggtttttgg
    51541 ccgtcaagta gtgagccatc tggtggcggt ggataattcc cggcgtatcg taaatataag
    51601 atccgtcgtc aagcggaatc tctattttgt ccaaggttgt ccctgggaag cgtgaagtag
    51661 tgatgacatt ctgatcaccc gtgatttctt ggataatagc attgattaga gttgattttc
    51721 caacgttggt cacaccgacc acatagacat cgcggccctt acggtagtgt tcaatcttgt
    51781 caatgacttc cttaatggca tgtttatttt gtgctgaagt taggaccaca tcgactggac
    51841 gaagaccttc ttcataggca cgtttcatga gccactggct aatcttacca gacttaactg
    51901 acttaggaag gatatctttt ttatttccta ccaagaggac atcattgccc gagacgaaac
    51961 gtggtaaacc tgggatgaca gatccattaa aatcaaagat atcaataaca ttgaccacta
    52021 aagcatcact gtctcccacc tcgtgcaaga gcttgaggaa atcatcgttc gtcaactgga
    52081 catctgtgat ttcattgtag tggcggagac ggaaacagcg ttggcaatag acttcgccag
    52141 tctccaaacc tttttcaagt gccgactggg gggtaaaacc aagaccagct ttatctgtcg
    52201 tctgaatggt tgctccacaa ccaatacaga gaatttcttc catagttaaa ttcctttttt
    52261 atatgtaatc ggtccgtact tttcagtgat ttttctcata acacgacgct cacgagttcg
    52321 gttaatctgc gttttgattg agtcatgttg gaccaagggt ttgactaaaa ttgaccgaat
    52381 ccctgcacgg tgggctgctc gtatatctgt catgagctgg tcgccaacca tgaccacttc
    52441 ctttttgtca tagtggaatt ccttcatagc acggtcaata ccaaatgtga agggcttcaa
    52501 ggcccagtaa acgtaatcaa tcccaaattt ctcaactgct cgttgaacgc gttttttggt
    52561 gttatttgac actacgataa tgccaatacc cgcgtcccga aggtcatgta gccattgctt
    52621 catctctggc gttccatcag ggttgttcca agcaatgagg gtattatcca aatcgaccaa
    52681 aacagccttg attccctgcg cctgcaggct tgggactgtc agatcataga ctgcttccac
    52741 agcaaaatct ggtatataat tttcaatcgc cattctggct ccttttctta actttttttc
    52801 gcaattttcc ttagtaacaa ggataaaaca atccacaaac ctgcactagc caaactgata
    52861 tagagccaag catggggctc atctgttaaa ggtaagggaa cattcattcc gaaaaagcct
    52921 gtcacgactg ccaaaacagc tagcaagact gaaatgatag tcaaggttgt caaattgtca
    52981 ttcagattat tgtttagaat attgttgtaa gaggctgaaa gctgctgtaa aatctgagag
    53041 attaggtctg tcatggatac cagctgatga gcctcaatca tggcatcatc aaactgttct
    53101 ctctcaatct catcaaaact acgatacaag gcatgacctt gaatatgctc taacaaaatc
    53161 cgattttgtt tggcagctgc cgtcagataa accataccag tctccaaatc agacagggca
    53221 aagaggtttt tcttggtagt tcgctggcgc aagaggtcat tgacctcatc cctactcttg
    53281 tccatctgct caatgacagg atagtaggca ttgctgatga tttccagact ggcaaagaga
    53341 aacttataaa tcgaaagcgt gtcatggttc tccagataac gagtcatctg ttcaatgaca
    53401 taggcgttct tggtattact aatggtaatc aggcgacgat gctcgacgat aaaggtcatg
    53461 ggaaaagtct catagtaggc cttgtccttt tttacgtcta ggacattata gataaaggta
    53521 accgtcccac tttcacggtg gtagtccatg tgggcgcgct cgtttctatc cagtgcgtat
    53581 tcaatggttt ccttgtccaa accgtaaatt tcagaaaggt cttctagttt attcaacttt
    53641 cctaggtcta ggtctatcca ggtacaacca ttgcccaact gcttttctaa aaccatcttt
    53701 tctccttatt aaactccctc tattgtacca caaattactt aaaataacag gtctagtctg
    53761 tgcgtgagaa attgctaaca actgtgatat ttcggttagg gacaaagtga agggcttgct
    53821 cctcgctacg aagctgtgtc gtacgaattc ccacactgac aaccttaccc gatacagtaa
    53881 tcggtccatt tgtcagaacg acctcatctc ccacatccag ttgacgttca aagaggataa
    53941 aaaagccatt aatgacatca gacagaaagc cttgggctcc cataccaatc gctaccccag
    54001 caataccagc tccagccagc aaactagaaa ctggcaaacc taaaatcgac aaaatgcagt
    54061 agagtaaaaa gaaatatagc gtataattaa acacattttc tagtaaacgt gagatggttt
    54121 tttggcgtcc gacatcatga cgagacattt ttagagaagg tttgacaatt ctctgcacca
    54181 tggtatgaag cattttttta gcaatataaa atacaatcaa aagcagtaaa agagaaatga
    54241 ccttggttag aatattctcg ataatgcttg tcacatctag cttttcaata taagcctgaa
    54301 taaatttttg catataaaac tcctttattt cattatacca tattttcatc agtctcattc
    54361 tccataaata ttcaaaaaat agacagaaaa ttcttgattt tgtctatcat ttatactata
    54421 atcataatca ctacacaaaa aggagattat tatgaaaaga atcattcatg cttggaataa
    54481 ggcaagcctt gtcaagcgta tcttgattgg tatgctttgt ggggaatcct agaactgacc
    54541 cttcctaatc tctcagggat tgggctactc ggggatttat tcgttggagg tctaaaagct
    54601 gttgctccta tcctagtctt tgccctcgtt gccaatgccc tttcccaaca tcaaaaggga
    54661 caagatagca atatgaaaac tgttgttttc ttgtatatcc tatgatagag actttcgacg
    54721 ctgctcttgt agctgtacta gcaagtttca tcgtccctat tgaaattacc ctaaatagtg
    54781 ctaatactga aattgcacca ccagatggga ttgggcaggt cctcagcaac ctcttgctca
    54841 aactggttga cagcccagtc aacgccctgc ttactgctaa ctatattgga atcttatctt
    54901 gggcagtcat ttttggaatc gctatgagag aagccagtaa aaccagtaaa aatagtaaag
    54961 aattgctaaa aactatcgct gacgtgactt ctaaaattgt cgaatggatc atcaatctgg
    55021 ctccatttgg aatccttggt cttgttttta aaaccatttc tgacaaggga gtcggaagcc
    55081 ttgccaacta cggtatttta ttggttccat tagtaacgac tatgcttttt gttgcccctg
    55141 tggtcaaccc tttgattgcc ttcttcttta tgagacgcaa tccttactct ctagtttgga
    55201 actgcctccg tgtcagcggt gtgacagcct ttttcactcg tagttctgcg actaacattc
    55261 ctgtcaacat gaaactctgc catgaccttg gactcaaccc agatacctat tctgtttcta
    55321 tcccactcgg ttctactatc aatatggctg gagtagcgat taccattaac gttttgaccc
    55381 ttgttacagt taacactctt ggaattcctg ttgactttgc cacagccttt gtcctcagtg
    55441 tggtagcagc tatctcagcc tgtggtgctt caggtattgc cggaggttcc ctccttctta
    55501 tcccagttgc ttgtagcctt ttcggtattt ctaacgatat tgccatacaa gttgttgggg
    55561 ttggttttgt gattggtgtc atccaagact catgtgaaac agcccttaac tcttctacag
    55621 atgtcctctt taccgccgtt gccgaatacg cagcaacccg taaaaaataa ctcatcaagg
    55681 caagcctgct catgtcttgt cttttacgct tttattctaa cttattagga aattcttatg
    55741 tctattagcc aacgtacgac caagctcatc ttagctacct gtcttgcctg cctgcttgct
    55801 tattttctca atctttcgtc agcagtttcg gctggaatta tcgctctctt gagcctatct
    55861 gatacgcgta gaagtacttt aaaactggct cgcaatcgtc ttttttctat gcttctagct
    55921 ctggctatcg gtgttctagc ttttcacttg agcggatttc atatctggag tctcggcctc
    55981 tatctggcct tctacgttcc tttagcctac aagatgggct gggaaattgg catcacacca
    56041 agcactgttt tggttagcca tctcttggtt caagagtcaa cctctccaga ccttctagtc
    56101 aatgaattcc ttctctttgc tattggtaca ggatttgcct tgcttgttaa tctctatatg
    56161 ccttcacgag aagagaaaat ccagcactac cacacgctgg tggaagaaaa gttaaaagat
    56221 atcctccagc gcttcaaata ctatttatcc agaggagacg gacgcaaccg agcacagctg
    56281 gtagcagaat tagacacgct tttgaaagaa gccctcagac tggtctattt ggatcactct
    56341 gaccacctct ttcaccagac cgactaccat atccactact ttgagatgag acagcgacaa
    56401 agtcgtatcc tgagaaacat ggcccaacag attaacactt gtcaccttgc cgccagtgaa
    56461 agcctgatct tagcgcaact cttttcaaaa attgcaggtc aactgagcca gaccaatcct
    56521 gcttctgatt tgctagatga aattgaacgt tatctggaag tcttccggaa ccgcagtctg
    56581 cccaagacaa gagaagagtt tgaaacccgc gccactcttc ttcaactcct acgtgaagcc
    56641 aaaaccttca tccaagtaaa agttgatttt taccaaaaat atggacagta aaaaagaaaa
    56701 ccactaaaaa acagagcttg ccagcattct tgaaaagtag tataattatt gcatgcgcaa
    56761 tcatcttgtg acgcagagac tgcccgttaa tggactttct tctatattat gactctaaaa
    56821 agaaaggaga cactatgacc tatttggaaa aatggtttga cttcaatcgg cgtcagaaag
    56881 aaattgaaag tctcttggaa gagaccattg cccaacagag cgagcaaagt ctgaccttga
    56941 aagagttcta cctgctctac tatctggact tggctgaaga aaaatctcta cgccagattg
    57001 acctgccaga taaacttcat ctgagcccga gcgcagtttc taggatggtg gctcgcttgg
    57061 aagctaaaaa ttgcggtcta ctcagtcgca tgtgttgcca tcaagataga cgctctagtt
    57121 ttatctgcct gacaaatgat gggcaaaaga cactggcctc gctacaaaaa actgtcgaag
    57181 aaagcttgga agcaggtttg gatttcttga tttaagatga tttttaaaaa aagttgcgtg
    57241 cgcaatcatt tttcttgaca ttctctttta taaggagtaa aataaagtta gcattaaaca
    57301 aaggagtttt aaatatgatt gaaattacct atatagatgc cagcaagaac gaaagaactg
    57361 tgactttcga gtcttatgaa gactttgaac gttcgcaaca agcttgcctt atcggcgtcg
    57421 cagactacta ccctgtccaa aaattaactt acaagggtca taatttggac taccatggga
    57481 cttatggaga tatcttcttc tatctcatga aacaagattt aagccaatat aactaaaaaa
    57541 aggagaaata caatggcaaa agcaattaca gatgcaacat tcgaacaaga aacaaaagac
    57601 ggtttggtct tagtagactt ctgggcaact tggtgtggtc catgtcgtat gcaaggtcca
    57661 atcttggaca aattgtctga agaactttca gaagatgtct tgaaaatcgt taaaatggac
    57721 gttgatgaaa atccaaacac agctcgtgct tttggaatca tgtctattcc aactcttctc
    57781 ttcaaaaaag acggccaagt tgtcaaacaa gttgcaggtg ttcacacagc agaacaaatc
    57841 aaggccatca ttgctgaatt gagctaatca aacgagagac caagtacttt ctttggtctc
    57901 ttttttcttg ccctttgcta tttttcaaaa aatatgctag actatagtat attgaaacta
    57961 gaatagtacg cctctacttc taaaacattg ttagaaatcg atttgactgt cctgatcgat
    58021 ttgtcctgtt cttatttcat tttactatat aagtagaata ttacgatgtt tgggatatgc
    58081 catcgctaaa aaaacctcga tttggtattt tttagctccc taatgggagc tttttgcgtg
    58141 ctctgaacat ttcccatttt ggaaggagta ctatgaaacg tcaatcagcc ttggtcgtct
    58201 ttagtggtgg tcaagattca acaacctgcc ttttctgggc catgcaacac tatgaaacag
    58261 tcgaagctgt cacctttgcc tacggccaac gtcatcacct cgaaattcaa attgctagag
    58321 aaatcgctaa ggaacagggc attcgtcacc atatcctcga tatgtctctg ctgggacaaa
    58381 tcactgctca gccagacttt gcgacgattc atatttccta cattcctgac aagctctgtg
    58441 tcgagtcaaa acccctcaaa ctatatctat ttagctaccg aaaccacgga gatttccacg
    58501 aaaactgtat caacaccatc gggaaagact tggtcaactt gctagaccct cgctatttag
    58561 aagtctgggg aaaattcact ccgcgcggtg gcatttcaat cgacccctac tataactacg
    58621 gtaagcaagg aactaagtat gagggcttgg cagaacaacg cctcttccaa cacgaccttt
    58681 atccagagaa aattgacaac cgctaaactc atactcaatg aaaatcaaag agcaaactag
    58741 gaagttagcc gcaggttgct caaagcagtg ttttgaggtt gtagatgaaa ctgacgaagt
    58801 cagtaaccat acctacggca aggtgaagct gacgtggttt gaagagattt tcgaagagta
    58861 tcatacgaaa aagccctgtt cctcaagatg aggagcaagg ctttttgagt ttcaattatt
    58921 cttctgttcc aaggaaattt tttgcaacaa gggctgcaag aactccacca gcgattggtg
    58981 caaggatgaa aatccaaact tgttgaaggg ctgcgccgcc taccaagaca gctggtgcca
    59041 agctacgagc tgggtttact gaaagtccag taatcttcaa tccgacaaga atcatcgcca
    59101 tcaatgacaa accgattacc aaaccagcaa tcgcgccatt gcccttgctt tctgaagtca
    59161 cagtcatgat aaccaagaca aacaagaaag ttgcgatgac ttcaaacaag aaaccaccaa
    59221 agacagtgac accgtttgcc aaggcatttt caccaaggct agcagttgac atacctgaat
    59281 tacccaagag gaagaagact gcgccagaag cgatgaaagc tccaacaacc tgaccaagga
    59341 tgtagtttac aagttctgaa gatgacaaac gtttgtttac aaacatagca atcgaaacag
    59401 ccgggttcaa gtgagcacct gaaacagttc cgattgagta ggctgccacc acgattgcca
    59461 aaccaaaggc aaaggcgatt ccaaggtgac caaggccatc aaaaccattt ccaaaaacaa
    59521 cagctcctgt cccaacgaac acaagcatga acgtaccgat taactcagca acaaattttt
    59581 tcattttctt tctccttttt tcaaaaacta gatactagtc tatcaaaagt aggaaagggt
    59641 ttcaagaaaa ttgattggaa attttttgaa aatcatagaa ctattagcta atccctagta
    59701 ttgaaaagac tggatagctt ctttcaggtc atcttgtaaa ctatttctct ggtcaagttg
    59761 gacatagact tccaccagac aggatctaaa gttggaaaat ttgtaaaaat cctccctttc
    59821 ttctatcgga aaatcaacag tttttatcca agaagctact tgttcttgct ccaacttccc
    59881 ttgtaaaata ggttcataga tcactcttgc taaacgccaa tcctcatcat ctgtaaagcg
    59941 aatcgacatt cttttaaata gttggccaag tatgtcaaat acttcatgaa ttctgtttat
    60001 aggaaagtct ggatgacaga ccacctctgt cagtaaatcg gctccatgtg caaaagaatg
    60061 aatccaacca tactgacttg agaaacctgt tgtatccttt tcttttgaaa gatagtgcaa
    60121 gccttgattt gaaaagacat tacgaatttc taattgtaat ccctgataaa aaaccgattg
    60181 ctggttggca tctgcataca agagatttgc ataaacaagt gccctaaaag aacgttcaag
    60241 tgttggcaga cctaccttat caatctcttt atctagtcct acatcagatg aaaccccttc
    60301 agcaatgaaa tgaaattgct cctgtgtaaa tagctcttcc tgaatccctc tagcaaagct
    60361 tgtaaaaaca aggtcatcgc gaatttctgg agaaggatct cccaaatgat caagcaacca
    60421 ctggatttcc tcctggttat aatttggttt ttcttctgct atttttctta gtaaatcttg
    60481 atacatggtc aatacctcta catttctagc aactgttcaa aaaagcagtc ttaaatgacc
    60541 ttaccaattt gtaaaattaa gttaaaaaga aaaagacatt tatagtcaga gaaacagcat
    60601 atttctgaaa agatatataa atgatttatt ccatattaca acaaataaac ttgtaatgat
    60661 agagccttat cacaaaaatc acattcctgt ctcaaaaatt gcgaaaaact agttataata
    60721 aagtgaaata aaaactatac aaattgatta gggaatttaa aacaatttct aacaatattt
    60781 taaaaactga accgtactat ttcaacttcc ataaattaca atattgatag gcacagttcc
    60841 catacctgcc caaattcgaa taacgtttag tataaattag aatatgacta caacatcaca
    60901 aataattaga ctatctataa tatctacgat gtaacatata cataggaagc accgttatca
    60961 agagcgccaa ggctatcaac cagataagat gaagatacaa acctgtcacc tcacctcccc
    61021 atataatacg aatcatgcga gtagcatgat acaagggaga aaaccaagtc aaatcaccaa
    61081 gtattggggg caaggaagta atgggaaaga aggtatctga aaacatataa agaggacgga
    61141 ttaccaaaac attgtagtaa ttcagaaatt ccctagacgg cgccaagtag gtaaagatta
    61201 gtcccaaaac accaaacaaa taacccacta taaataaaat cagaggaatc aataacatca
    61261 agacatgaaa atgcgctgtg ataagcatag aaatcagcca aaaaatccca ccgaaaatca
    61321 ctgcacgaat acctgcccag atagcctgac ccaccacaat atcactcgta ttgattggcg
    61381 tcatcaatat agcatcataa gtcttttcaa tcttatactg gataaaggca ttgaccgttg
    61441 tttctgcggt ggccgcagac atagcagtcg cagcaattaa acctgtaatg acaaaatcac
    61501 ggtagagcat accgttaaca tgcgtcaaat aggcaccaac tccaaatccc attgctaaaa
    61561 gataaaagag ggggtcgata aggttgggaa caattgaaat tttaaataaa tttctaaaac
    61621 tcatgtagtt gcgtaccaca acgtgtccga tggagtgaaa tgataactta aacatgcaag
    61681 tcctccttct ctgtcccagt caaccccaaa aaaagcgtct caaggttgtc agcatcatac
    61741 ttgatgagca agtcttctac agttccttct tctttgatag tcccttggtg gagcatcagc
    61801 accctatctg tcaaatattc aatctcattc atatagtggg aagtaataat gatggaaaca
    61861 cctaattcct tcaactccaa aagtttatcc caaataatat tgcgggattg aatgtctaaa
    61921 ccaactgtcg gttcatctaa aatgataata tcaggccgat tgatgagagc tcttgccaag
    61981 acaagacgtc gtcgcatccc acccgacagc tgattcacca tcttttgcgc atgtttgctc
    62041 agttgaacaa aatccaagag agaatcgatt ctcttcctaa gttcgacaga tgagatacca
    62101 tagcatagac cgtgagcaaa aagattatca taaacattca aggtcatgtc cagcatatcc
    62161 tcctgcccta caatacccag acaagattta ctcttacgac gattggtttc aatattttgc
    62221 cccaagatat caatctctcc tgaggaaatt gaggtcagtg agtaaatcat ctttaaagtg
    62281 gatgttttgc cagcaccgtt gattcccaag atacccaaac actctccttc tcccaattca
    62341 aagctaattc ccttgacagc ttcataagaa ccatattgct tttttagatt tttaacactt
    62401 aacttcttca ctctttcttt cccccacaaa tagagcatgt tggatacttt gttaattcat
    62461 ctcacttttg aaaaaatgtt gagggacgtt aatcttaaga ttaacgtccc tcaactgtgg
    62521 atactgctgc aattactttt gtaattttac ctccatttaa actcagacaa taaaatttaa
    62581 aatattctct agtaaaacat ttttaaaatc tatttttctt gtgctttaat tatagtataa
    62641 taaaagatag aaaatcatcg atatatgaaa tttggagaaa atttttatgg aaccagatat
    62701 tttcatcatc acaaaactct tatcagaccc ttctcggatg cacattttag atattctaat
    62761 ggatggaaaa gctcacacgg ttaacgaaat tgccagcttt accaaaatca agcaacatac
    62821 tgtcagctat cacctcaaat tacttaccga agcgcaggta accactctac aaacctatgg
    62881 acgttttcat tattattctt taaaaagtgc tgccattgca gaaatgctgg aatttctcag
    62941 cttctactct cctcagcgtg atgtcaaaag ttataaacaa cacattcaca aaaaggaatt
    63001 aaaagtcgct cgcacctgct atgaccatat tgctggtgag cttggcattt ccattaccaa
    63061 ttatctcttg caagaaaatc tcctcagcga atcagaaaaa gacttccaac tcactgaagc
    63121 tgggaagtct tatttccaaa gaaaattaca cattgatacg gatgaattga aaaagaaaaa
    63181 acggaaattt tgccctaaat gtttggattg gagcgaacgt aaaaatcatg tcggcggagc
    63241 tctcggcaat gctcttttag aatttttcag tgaaaaacaa ttggtcatcc ctgcacaaac
    63301 gccacgttca cttaccatta cagagaaggg caaagaattc ctcgaaaagg aatgggggat
    63361 ttaaacatgg aattttaagc aaataactgt ccatacccat tctataacaa cctctctatc
    63421 cccttactcc cccaactcag cactgtaggc gataatctgg tcaactgtgt cagacaagaa
    63481 ttggatggta tcacggagtg gtttgtctgt tgaaatatca gcaccgataa tcatggctga
    63541 ctcaagtggt gtcttgctac cacctgattt aaggagattg agccagtctt cagctccagt
    63601 ttcagaatgt tttagatgaa ggtaaccagc agtcgagata actagtcctg ctgagtaagt
    63661 gtaactatac aagcccatat agtagtgagc ttggcgcatc caagtcaaag ctgcatcgtc
    63721 gtcgatttca atggcatcgc cccaaaaatc tgtcaaaact tccttcataa tactgttgag
    63781 tttgcttgct ccgaaggttt ctccttcttc aatcaatgta tacaccttac gctggaaggc
    63841 tgcttccaag aggtgggtga taaagttatg gaagtaggtg tctgtcaagc gatgagccag
    63901 agcgaagcgt ttttgacgtg ggtcattaga ttggttctct aagtaatcac tgagtagcaa
    63961 ttcattgaag gttgacggtg cttcaacata gtaggtcgac atatgggcat tgaagtaact
    64021 ttgatgattg tctgaaaaga tgaattgacc agaatgcccg atttcatgaa tcaaggtata
    64081 gacatcgctc aaacggcctg tccagctcat gaggacataa gggtgtacgc gatatgggtc
    64141 cgccgcataa ccaccggaat ccttgccact gttagcagca aagtccaccc agcgctcttc
    64201 ttggtaacga gcaacttcct gacaatattc ttgccccaaa ggttctaccg acttcatgac
    64261 caaatcatag gcatcgtcaa tagtcacttc aggattcagg gcgctgtcca agtccaattt
    64321 ccagtctgca aaggtcatct tttcaagacc atttaccttg gcaacatgct tgaggtatct
    64381 ctgagcgact ggtgcaaagt ccttcatgat gaggtcaatc tggcgatcaa acatgacacg
    64441 gtccacttct tgttcagcta gaagataatc aaagacagag tcatatccct tcatatcagc
    64501 caagagtttt tcagacttga cctgagccag ataggctgct gcagccgtat tttggtgctt
    64561 acgaagtccc tctgagaagg aacggaagga tttctcacga acctcagcat cctcgtgatt
    64621 ttggtagaaa ttctcatagg tgacaaagct gtttttgtag gtcttgccat gggcttcaaa
    64681 gtcagccatt tcaaaatccc cagctcgcat cttagtataa atgtcctgcg gactatagaa
    64741 aacttcaccg agattggtca aggccttctc cacatcagcc cctagatagt gggctttttt
    64801 gattttggcc tgacgaatag ctgccgtcaa gtgaggcaat tcacccaaac ggtccaagac
    64861 ttcctcgtct gctaccacca aggcatcgtc aaagaaggtc aaggctacgc tggcatctgt
    64921 ttcaaattcc atcccagctt gggcaatatt ggcaaattcg tcattgctat agtccgtcgt
    64981 ctgaggcata aaagcatagt tgccaatatg gctcatctga atgtagatct gttccaattc
    65041 cgcaaaggcc ttctcgaaat tctcaaaagt gtgaagattg cccttgtaat cacggctaaa
    65101 ctggttgatg tcttcgcgag ctttctcgat tgcacgcaag aaatcctcac ggtcttggta
    65161 tagggctgtt aagtcccaga gttccttctc tggaaattct gaacggtgtt tttgttccat
    65221 tttcttcctc ttatttctct aattctacta aaacactaag ggctgataag gcgtaaagcg
    65281 gtgctgtttc tgctcgcaaa atacgaggac ctaggcctac caaaacggct cccttagctt
    65341 caaaactttc gatttctgca ggtgacagac cgccttctgg accaaagata aagagcagtt
    65401 tggctcctgt ttcaagacca gtgactgctt gcagaagcgc agcggcttct ccttctttag
    65461 ctgattcttc ataggctact atgatagagt caaactggtc cagctgagct agaaaatctg
    65521 cttttttctc gaaaagttta atacttggta caatattacg cttgctttgc tcggctgctc
    65581 caagggcaat tttttctagt ttttcaactt ttttacccaa tttcttgcca tcccacttgg
    65641 caactgacca gtctgcagga aaggcccaga tttggctagc acccagttcg gttacttttt
    65701 gagcgatgaa ctccagcttg tctcccttgg gaaatccaga tgcgatggtc acttggactg
    65761 gtagttccac attgtcattt aattcttgga ccaactcaaa ctgacgattt tccatatcca
    65821 gcacgcgcgc caagcgcttg atgccatcat caaagactaa ggtaacctca tcctcttctt
    65881 tcaagcgcat aacctgaaac atatgcttac tggtttcctt gttctcgata gtgacaggag
    65941 agatagcact gccttttaca aaatactgct gcatgctagc ctccaatcac accagagata
    66001 tccttggttt tcttaaagac acaggcattc cattcccctt gaaccatgtg agtttcgagg
    66061 aaaaatccag ctgattcagc caactcgcgc accatgtccc acttatcctt gataatgcca
    66121 ctcatgatca ggtaaccttc atccttaacc aagcgataag catcctctgt cagatgaatg
    66181 aggatatccg ccaagatgtt tgccacgatg acatctgctt caatctccac gcctttaagc
    66241 aaatcgcctg ccgctacatg gatattttcc attccagggt tgagctcaat attttcctga
    66301 gccacacgaa ctgccacatc atccaggtca taggcgaaaa tttctttagc ccccagaagc
    66361 gagctggcaa tagagagaac ccctgaacca gttcccacat ctagcaccgt ttcgccacca
    66421 cgaagaacct gttccaaggc aaaaaggctc atcttggtag ttgggtgggt tcccgtacca
    66481 aaagccatgc caggatccag cttgataatt ttttctcccg cagtcgcctc atagtctgtc
    66541 caagagggaa cgatggtcaa atcatgagtg atgcgagcag gttcatagta tttcttccag
    66601 ttgtctgccc agtcttcctc agccaaggca gtcgtaccta tttttaactc tcccaaatcc
    66661 ataaaatctg tcaattctgc tagacgagcc tgcaaatccg cctcaaccac tgtcacatcc
    66721 accgtgtcag ggtagtaggc tgtcactacg atttcttctt gctgctccac ctctgggaaa
    66781 atctctccaa agcggtccac atttcccaca tagtccatac tgtcttcgat tgcgactcct
    66841 tgcgctccca gctcaatcaa gagattggaa accaactcct ctccctcacg cttcactgta
    66901 acttttaact cttgccatgt ttccattatt aataccaagc ccgtaaaaca caaaaccaaa
    66961 ataggaaatt ctctgaagac gcttgtgtct aagagaagtt tatctttttg gcaccgtgtt
    67021 tagggcgggt tcagtttaga aatttaaccg aaccatcctt tctaatcact tacttttaaa
    67081 taatctttta atctctcttg caactgaggc acaacttgac tggaactaag aaattcctca
    67141 acattcatca gctgatagcc ctgtccttca tctccaaata cgatactgtc aaactggttc
    67201 tgtgtcaact gaccaactag aaaaacggac tgtttgtctg caaaaagcat acttgggtaa
    67261 accttactcc aaagcagaca atcttcagtc agatgaatgc ccagttcttc ataaacttca
    67321 cgcgctacac actcaaaagg actttcatca ccttcacgtc caccacctgg cagttcccac
    67381 atattggccc agggaatact tgccttatca tcgcgtaaga tagtcaaaag cttatcccca
    67441 caaaacaaag caatcttgca acctgtgaaa tcagaaattt ctagttccat cttcagttcc
    67501 ttctaacatt tccttttcca gctcggctaa ccagttttca taatatcttt tctcatccct
    67561 caacattcga ctactatcca ttttctgtct agcaatcttg agagccttac gagttcgatc
    67621 tacatctttc ttcaccttta attgatacca ggcttgtatc acttgaagat tggacagttt
    67681 gagagacaga aacgatttga cctgtcgaat actagcatat tgctccgctt gctcaaaatc
    67741 tccttccaac aaggcgatat gaagcaggga tagttgggca actgtctgca tcatcggagt
    67801 agttgtcctc tcaagtaatg cttgaaactg ctgtttagct acttcttcct tcccttccaa
    67861 aatggaaact tcaccttgca tacctaatac accatccgca aaactccctc gtgcatcctc
    67921 aggaactgct tgaacaaagt ctttcaaatc atattcttga ggagctagca aggtctgggc
    67981 agaatgtctc aataccaggt aggcgtattt ggtattttca gggtgttgta gtaattccca
    68041 aatttttgct ccatcggtga tgtcgactgg caaaatgtta tttaggaaga aagataaatt
    68101 aagaaaaatc caagtccctg caaaatacca gcttcttgtc aaaaatccaa acaatatcgc
    68161 caataatatc aagccgagat gaaccatcaa gcctcctgaa agcatcagga tgattctttg
    68221 atcgctttca tcctctttta aaccaatgta ttgagcacca acatttttca gaatggctgt
    68281 tctactaaga tgaaacctgc ctgacttttt ggtcaaaata aaatgtccta atccaaaagc
    68341 caccagccga tagcctgtca agtagccaca aaaagcatga cccagctcat gaagaataaa
    68401 gattaaatac atgcttagaa gagcgaaggc ataaccaaaa gtaaaggcta aaactgcgga
    68461 ataccccaac tctgcaaatg cgattgttcc acaagcaaaa gctagcataa taaagacaac
    68521 agctagcaca taaaccaaat aagtcccaat tttcttcata acacctccaa ccaactccta
    68581 gtattttgga taaggataaa attctccctt ttccaagcca atttttcctt cttcaaagac
    68641 ttcttggttc cattccatga caaattcctc tgcttctggg tcttccaaaa agtccatgag
    68701 gacatctagc ccaacctcag cagtatcttt aaggaaaagc gcaaaataag ctaaaaattc
    68761 acgggaaaat ccttttttag gcaggtaagg aataacagtc aaatagtctt cctcattgac
    68821 tgttgacttg gcaggattgt agaaaaggac cgcttcctca aaaagaatgt catctgatga
    68881 aacctctccg tcttcatcca ccatctccac acctgcagca ttttgcgctt ccaatagaaa
    68941 actcacttct accgcatggt tgcgtttgtc ccagctaatc tcaaagtcaa agggaaagtt
    69001 cttgtccaac tcttcctcta aaatatctaa aaatccgtat gttgccattt tgtcctcttt
    69061 ctatgcgact ctttaatcgc cccgattgct cggaaatatg ctaaaataga tactaccatc
    69121 ttaccacaaa attattttat gtcctaatta taccatatta cctcatttaa acccttggta
    69181 tcagtgattt tcttaaaagt ctgatttctt catttctcat aaaaatcaat ataaaaagcc
    69241 ctcgaaaggg ctaataaatc tataaaatca ataggcgagt aactagcaca agtggacgtg
    69301 cttttttatt gactattacc acgataccac gcttaatctt aggcttgaac tttcttatct
    69361 gcaatagcgt ctgtcaaagt ctgagaaaag ttaagcccca tttctcgtcc caacttatct
    69421 gcccattttg gtatggtcaa agtcttttta atgggttcct gacttcctag gtattctgat
    69481 acatcaacag ataccataga aataaaagat ttatcaaggt cataggttga cacgaaatct
    69541 tcatcatctt taaaaggatc attatcaatt aaagacaagc tattgatatc tgatggctga
    69601 ggtaactctc catcactctc tatcaaatct gcaacagtta tccctagcca ctccgacccc
    69661 atagccaaag cctcagaaat cccctctcct tgtgtagctg agtattcaaa atctgggaaa
    69721 tggacaaaat aagtcgcttc tgttccgtct gtgtcgtcat aataaaataa agctggatac
    69781 gtaactaaca tttcactacc tccatatcaa aaagcagggg ctgaatttta caacccagct
    69841 tgctttctta tccctctttc agtgtactta ttcagctcac catgaaggat tgtgataggt
    69901 ctttcccctt gcttttccat tttaatatgg gagcctttac cgcctctagt ctttatccaa
    69961 ccatgggccg taaggagttt aaccatctct ttttgtgtca taggcatagc gcttttacct
    70021 cctgacaaca ccattataac acgtgttaca cgtattgtaa aggagtgata cttattattc
    70081 tattatacat aaaagcccct agatgtggtt ctaagggaag ccaatttatt catacctatt
    70141 tttctaatga gtagtaaaaa ctgcttcttt atcgagcaat tcatcatctg tatagtcaat
    70201 tgtaaaagta tctcgatcta agacagattg aggcggagtt gaatgaatca taggaacact
    70261 gcgtactcta tattttttat ctccaatttt tacaaactga tactcttcga aaatcaaatt
    70321 caaaccacgt caacgtcgcc ttaccgtact caagtacagc ctgcggctag tttcctagtt
    70381 tgctctttga ttttcattga gtatgattaa ctctcaagtc ttcgaaatca ggattttcaa
    70441 cagttattac aaggaggcga tttactactt caaaaacatc aattattcta tttttcatat
    70501 tttttcaacc cattattaga atgaacttct tggtaagcaa aatcaagttt agatttaatg
    70561 ttttcgtaca aatctaaaat ctcttttgga gtatcttccc ggaagaaaag ttttcttttc
    70621 cctgaaataa cttgatcact aagaatccaa tgacgaattt gttttgtaaa aatcaaaatt
    70681 tcctgacttg gtagttccat catttccatt gcttatcacc tctcttttca ttatagttca
    70741 tacaatgaca ttcagcaata ttatttctca agtcagcact tccacttctt taggctcaac
    70801 tatcctattt tgagctttaa ggaaaatcaa atctctcatg ctgatacctc tcctcattaa
    70861 attaaatagt aaaaaagatt ctatctcact ccctgattat tacaaaacca ttgaaatatc
    70921 acaactaata ggctagaatg gacatagtaa gatatagtag atgagtcatt ctactcaaat
    70981 ccacgttaga aaggactgct atgccagaca atctcgcgct tcgcatgcgc cctaaaacca
    71041 tcgaccaggt catcggtcag gagcatctgg tcggacctgg aaaaatcatc cgccgcatgg
    71101 tggaagccaa ccgcctgtcc tccatgattc tatatggccc tcctggaatc ggcaaaacca
    71161 gtattgcctc tgccatcgct ggaacgacca agtatgcctt tcgaactttc aatgcgacag
    71221 ttgatagtaa aaagcgactg caagaaatct cggaagaagc taaattttct ggtggtctcg
    71281 tcctattact agacgaaatt catcgactag ataagaccaa gcaagacttc ctcttgcctc
    71341 tcttggaaag tggactggtc atcatgattg gagcaacgac tgaaaatcct ttcttctctg
    71401 tcactcctgc cattcgtagc cgagttcaaa ttttcgagtt ggaacctctg tctaaccaag
    71461 acgtcaaaga ggccctgcag atagctctaa gtaaccctga acgtggtttt gattttccaa
    71521 tagaactaga tgaggatgcg ctggatttca tcgcaacctc tacaaacgga gaccttcgct
    71581 ctgcctttaa ctcactggac ttagctgttc tctctacccc tgagaatgac gagggcattc
    71641 gccacatcac cttagacatc atggaaaata gtcttcagag aagctacatc actatggaca
    71701 aggatggaga cggtcactat gatgttctat ctgccctgca aaagtctatt cgtggctcag
    71761 atgtggatgc cagtctccac tatactgccc gcttgattga ggctggggat ctgcctagtc
    71821 tcgctcgtcg cttgactgtt atcgcctatg aagatatcgg cttagccaat cctgaggccc
    71881 agattcatac cgtgactgct ctggatgctg cccagaagat tgggttccca gaagcccgca
    71941 ttctcattgc caatgtcgtg attgatttgg ccctttctcc aaaatccaac tcagcctatg
    72001 tagctatgga taaggcactt gctgacctca aaacatcagg gcacttgcct attccgcgac
    72061 acctgcgtga tgggcactac agtggaagca aggaactggg gaatgcccaa gactatctct
    72121 atccacacaa ctatcctgga aattggatca agcaagacta tctgccagaa aaaattcgta
    72181 atcatcacta tttccaagca gaagatactg gtaaatatga acgggctttg gctcaaagaa
    72241 aggaagctat cgatcgtttg cgaaaaatct gaaatccttt tcaaaaaatt gcactttcct
    72301 cttgattttt tttgaaaaag tggtatcata taagtataga aacgctgtgg tgtacgactt
    72361 cacacttaag tgttgaccga ctattttttg tattattagg gaaacaaaag tcttctaaca
    72421 gcatgtaggc cgtctcacac ggaaacagct tcagttagag cgagttgccc acctgcttaa
    72481 ttgcgcgggt tcaatacaaa ccgtgaagtt tcggcaccaa tacagctttt ttctttgcct
    72541 ccttagctca gctggcagag cagcggactc ttaatccgtg ggtcacaggt tcgatccctg
    72601 tagggggcat ctacatacaa caggaaaagc cttggaacca aggttttttt gcttaaataa
    72661 aatttttttc aaattcttta gaaaactagc ttaaatcata atccaacacc aattttacaa
    72721 ataccataaa ctaagcttat atacccaaaa cacaaaaagt cctctttcca ctattttaga
    72781 aagagaactt tttctttagg agaaataact taatttttaa tcaattcgtg atagctcagc
    72841 tggcaccgtt aagtaataag ttgcagtcaa gcttgcttca ccttgattga caaaaatctc
    72901 gatggaattt ttatctagaa caacttccaa ttctttagct tcaatatcta cataccgtcg
    72961 actagtgtcc tgttcttctt cacctagaat tttttgaata agatggctac gatcaatgta
    73021 aacttgctgc gcattactgt cataaccaaa ttcaagataa tctgtatcat ttcctaagtg
    73081 gtaatgacaa tctttatcta tttggatttg atattggcct tttttaacag ggaattgtct
    73141 tagtttgcca tcttccaatc ttagaattct aggtaaagtc atagcacatg cccatttgtg
    73201 ttcttggtca tgggttggaa gggtacgccc ccatgtctgc atccaagcaa tcaggatacg
    73261 acgattttga tcgtccaaca atgtttgagg cgcatagaag tcttggccat gatcaatttc
    73321 ttgaactgat tctgggataa aacgtttttc tctccaatct accttacccg tgaacaaaag
    73381 cgatgagttg atgttatgat atgagtctcc ctcacgctga taacgcatgg gtgacataat
    73441 aaggcaatct ttcccatcta actcgaagta atctgggcat tcccacataa agccttggtg
    73501 ttctccccct tttaaaaaga tggattcgaa ctgccattct actaggttat cggaccctag
    73561 tagaacgata cagcccacat tatccttgtg tttggcagct actacggagt aatagcgtcc
    73621 atctttttca aagagttttg gatcacggaa atcagcagca atcaactcat ctggcaagtc
    73681 tgatccagtt gcaactggat tttgggaaat cttttcaaag tgaatcccgt catctgaaaa
    73741 tgccatattt tgcacttggc ggacaccggt tttttcttcg atatgcccag tgtacatgag
    73801 ccagaggcga tcatccttga caatggcaga gcctgagaaa caaccatttc ggtcataatc
    73861 ttgatcagga gcaagtgcca ctggcaagtg ctcccaagtc accaagtcct tacttttagc
    73921 atgtccccag tgcataggtc cccaaacact atcatatgga tagaattgat aaaagagatg
    73981 gtattctcca cgaaaataga caaatccatt tggatcattg atccaaccaa tctcagctga
    74041 aaaatgttct tcaggcttat attgagtatt aacgagatgt ttattttctg ctataaaacg
    74101 attggctttt tctactgtgt atttcttatc tcccataatc aacctctagt ttttgtttgc
    74161 ttggtattgg tcgtagtatt tttgtttaat agcgaggtaa ttagaaagtc cgtatttttc
    74221 aagttctttc ttgtaatcat cccactcagt atcaatattg ccatttacaa tccattcagc
    74281 acgtttacgg tagatatagt cattcatatc tgcttcgata tgggcaattt tgtccaaatc
    74341 ttcctgtgtc ataaagactc ttggatagtt attgtcattg ctcatgtaag gaacataata
    74401 ttctttgata agatccaaac gccatttggc atcatcaggt atggttgtta ctttaccata
    74461 gtatgaatct aggatagcta gtggtcctcc tacttcagtc ttttgacgaa gttctgctgg
    74521 tgcagttccg tttagtggta agtgttttag actatttgac gcttgatcca attcaaagat
    74581 gttttgttgt ttgtcatctc cgtaagttcc ccagttattt tgcacagatt ggagtggagc
    74641 gtattgtgca tcaatccatt tagctgtcaa ttctaggttt ttgtttacac tggtaataac
    74701 catcttgtca cgtgcaaatc ccataccgtt tgtacgagct acgtgttttt gaccacttgg
    74761 tccagcaagt actggtaaaa catcataact ttcgttactt ccagtaacat tattcttatc
    74821 ccatgtaaag taaacaccaa atttctgatc atgaccttta gcaatgtaac tattccaatc
    74881 atgttcgaaa gcttctttat caatcaagcc tttttcttgc aattgacgga taaatttgac
    74941 accttcttta tagttatcgt tatctgctgt gaagtcaact ttgccatcat ttcctactac
    75001 taaatgatca tcgttatccc ctataccaaa tgcagcaaat aggaatttaa aatcttcgtt
    75061 tccgttacca ctaataaatg aaaatggaat ttcatcagcc tctccatttc catttggatc
    75121 cccgtttttg aaagcttcta ggactttaat caaatcatca gtagcttttg gcatttcaag
    75181 accaagtttc ttaagccaat ctttgttaat ccaagccata tcgttgacgc tgtgaataga
    75241 ctctttacca tctccaagct cttcaatcca tgggaatgag taaatgtgcc catcaggtgc
    75301 tgtcatcaag gccttgtact ctggtttctc atccaaaatt ttcttaagat ttggcatgta
    75361 tttatcaatc aaatcttcaa ctggaataat aacacctttt ttagcccagt tcatcaagtc
    75421 cacatctgaa gctccgtcgt tgtggatagc atctggtaaa tcaccactag aaatatccaa
    75481 gttacgtttt tctgcaaagt cggattggta gttggtccag tcaatatgaa cgccagtttc
    75541 cttctccaaa cgttgcaaaa ttaacttttc atttgggtct ttaggagata acggtgaact
    75601 ggctgtcata aacttcaatg ttttcttttc ttgaagcggg aatgttacac cttccaactt
    75661 ataatctgga cttgaagctg tattttttga gccacaggct gcaagtactg ctaaactagc
    75721 tgtcaacaaa actgctgatt ttgagaatgt tttgaatttc atgagaaaac tccttttatt
    75781 ttttcttttt ttatccttta agtgaaccag ccataattcc tttatcaaag tatttttgga
    75841 agaatggata cataacaatc aatggcaagc tggaaatgac aatagttgcg tatttaatca
    75901 attcagctaa acgtttcatt tcattcatag ccgcttgtgc tccaatcatg tcttgacctg
    75961 gttggctctg aatgagaatt ttacgaagta caagttgcaa tggttccaag tttggatcct
    76021 tgatataaat cattgcatca aagtatgagt tccactgtcc tacaaaagca taaaggaaga
    76081 gaacaaacat aattggtttt gcaagaggaa gcatgatttt gaagaaaatc tgtaaatcat
    76141 ttgcaccatc aatgacagca gcttcaacta attcttcagg caatccttgg aaataggccc
    76201 tagcaagaat aatattccaa acgttgacag cacctggaac aatgatagcc catggagtat
    76261 tgagcattcc caattctttt acgagcaagt aagttgggac taaaccacca ccaaagaaca
    76321 tagtcacaat caagaagtag ttaatccaac ggcgccctac caaatctttt ttggaaagag
    76381 gataagctgt aaacacagat agcaagactg ttaaagctgc aaatccaaaa gagtatagta
    76441 gagaattgat aaaacctctt agaatagatt ggtcactgaa tacacgctgg taaccttcta
    76501 cagtccaatc ggctggatta aagctaatcc ctctactaac cagaacctta ggatccataa
    76561 aggatgctac gacgatataa agtaaaggaa gcaaagtcat caaaacgata aagacaataa
    76621 tgattttatt taagagtaag atacgtctat taaattttgt atccataatc gaatttttca
    76681 tactttcctc cttaaattcc ttcaccatta ttcatgcgtt taacgatttg gttaactgca
    76741 acaagcaata ctacgttaat cactgcatta aacaaaccaa ccgctgttga gtaagaatag
    76801 tctcctgata caagaccaac tttatagtca tatgtcgaga taatttcaga agttggcaaa
    76861 tttaacgatg tctgcatcaa gaatgctttt tcatatccga cattcataat tccacctgca
    76921 gctaaaacaa attggataac cataataggc ttaagagctg gaatatcaat gtgccagatt
    76981 cgttggaaga tattggctcc atccagtcgg gctgcttcta ctaaggctgg atctacattt
    77041 accaatgttg ccgtgtagag cgttgaagcc cagcccattc cttgccagat accactaaag
    77101 atgtataaag gtctaaagaa gtctggattt gtcaagaagt cagccttcat tccaaacata
    77161 gaaagaaaat tgttgattgg tcctcccact gaaaagaaga ggaaaatcat accgacaata
    77221 acaacgactg agataaagtt tggtgcgtat aaaatgagct gaattcgttt tttgactttt
    77281 tcactcaaga gttgattgag cataatagca agaatgattg gtggtaaaaa gccaagcaat
    77341 aaaccataga tacttaattt taatgtgttg gctaacaaga taccaaagtt gggagaggat
    77401 atgaattttg taaactcaga aaaaccaatc caatcactcc ctaaaattcc ttttaaagga
    77461 ttgtaatctt taaatgcaat taaaacccca tacataggga tgtatttaaa gataaaggtt
    77521 aaaactaaac cagggacagt catcaataac aagagttttt gtttcttgat tctttcccaa
    77581 agagaaactt gcttcgcttt gctattcata gcaacctcct ttttgaaacg tttcattttt
    77641 ttctagaaaa gatagcgctt ggcgctgtct ctttatttct ttttttgaaa cgtttcattt
    77701 ttgttttaaa aataaatctt tttatctgaa ttcattctat cattgatagc gctttctgtc
    77761 aagacttatt ttcatttttt gttgtttttc cttcaacaaa ttttactggt aggattgtct
    77821 gcaaattaac agtctttcca tcaattatat caaacaaaat acgaaccgct tcttttgcca
    77881 tttcttccaa tggttgttca atagttgaaa gtagataatc tctatctcca gccattttaa
    77941 ttccatcgta tccaataatt tggacatcat gaggaatacg tttgccattt ttttctagta
    78001 tttcaatcac atccaaagct gtaaaatcgt tgattgtaaa aattccatct atagaagaat
    78061 tttcttccaa gaaactctct agctttccat aatagtcagt aactgtctca tccaaatcaa
    78121 aaatactaag aggtatttta tgctcttgga catacttttc aaatgaaatt ctacgacgtt
    78181 tggtttcatt aatggttgta ttatgtccgc ccacaaaggc taaatgctga catcctttac
    78241 taattaattg tttagctgct tctcttccac ctgcatcatt atctgatgaa acacaaggaa
    78301 tggcaatatc tgagtatgtg cggtcaatac taacaaaggg aattcctgac gtcaagtaat
    78361 gttcaattgg actataggta atggcaacca ctccatcaac tttattatga cgcaacatct
    78421 ccagatagtc ttgctctcta tttgtaccat tgatagaaca taagagtaat ttgttatttc
    78481 tcttatagac ttcattttcc acatgcatag caaattctga aaagaaggga tgccagatac
    78541 ttggtacaat gattgcaatc gtttctgttc gatttttttt cattcctcta gcgtagtaat
    78601 ctggaatgta attcaaagtt ttaatcgctt gttccacttt tttcaaagtt acttctttaa
    78661 tgcctttttc tttattaatt acacgtgaaa cagttccaac actaactcct gcttctaaag
    78721 caacatcttt catggtaatt gattttcttt gttctaccat attatcacct cctttcaata
    78781 tatagtatca tgcaaatgct ttttaagcaa ctatttctca atcatttttg gccagatcat
    78841 ttatcccatc atgaataaaa tcactccaat tagcttttga aaatacttca attttcatgt
    78901 gtaaacatct acataaaaca ggaaaagcct tggttttatg gcttttttcg tatcttctac
    78961 aaaaaaagca agagttttag agggctataa atctagatgt acattttgct taaatgattg
    79021 aaggtctttt cttaacaaaa acaccccaaa aattagattt tttctgtcta acttttgagg
    79081 tacagttcaa acgcgaaata gcgttttttg ttatttttgg ttactcatct aatcgaataa
    79141 acatcatggc atttaacaaa tatatgagtg agaccgtgtt tatattattt gaatagatga
    79201 gtctcttatt ttcaatagga ggaataataa aattagaaat aatgatatca taaggtgaat
    79261 cttctaaaga ttcctttgat aattctaatt cagtccaaac ttccagttca aaattattgc
    79321 tacagtaata agaaagtgtc tctgcaacga attttgcatg atactgatca aaattactca
    79381 taaccaaaac ctttagttta ggctgatttt gtagcaaatt aatcaccaaa tgtttggtat
    79441 gagtgatgaa ggtataagat agatgattta ccatcattga actagaacaa acctcaagag
    79501 tctctaaata gtgagaaagc tcttttttta tatctgaaac aaattttgga aaaatatttt
    79561 gaaagttcct gattgtattc cctttttgat caaataaaat aaactcagta aacaactctt
    79621 gacgatacag atgtgcggta ttatgcagat gccaaatcag attatcctta ttctccattt
    79681 caatctgata cttgactgaa atctgatcaa taaaatcact caatagatgg taagattttt
    79741 caacataact atcctttttt acgcatttca taaagagact ttcatctatg aaaaacattt
    79801 tttgaaagta agacacaaat aattggcaaa caacttcttc atctaaagag atattgtatt
    79861 ctgattcaaa actctgagca acaccttcta ttccttctgc ctgcattaaa aaatccaaac
    79921 tttggtcgtt aaaagaatct ttatctactt ccataaaatg accaaacttt attctatata
    79981 ggttcgtaac taggagcaac tttagcattc tatgcgttga caaattcatt ggaaagcttg
    80041 tttccttata aaccaattct aacaattgag atagtggctc tgatgaaaaa ttttcaaatg
    80101 gccattctag gaaataatat ttttctgaaa aatattgtgc aaaaaagtaa cgaatgtctc
    80161 tctcatttcc aatgatttga acaggggtca aactgacttc aaattgaaat tgccttttaa
    80221 tcactttatt gatttggcta ataatacgat agagcgaaga tgaactgata taaaattctt
    80281 tacaaatact ctcagcttga caaccttcat taaagaagat gaattctaaa atcgaaaaat
    80341 gagttgaatg tttaaagaaa tgatggtaaa ccatttcaat atcactatca tcggtattaa
    80401 taatgcgtat accattagta gaagaatgaa aaatcaagtc aggaaaagca gatttaacat
    80461 gggatagatc atctttgact gcacgttctg tacaatttaa taactctgct agttcagaac
    80521 gatgaaacca acgtttatgt tcaaataata attctaataa ttctaattgc ctatgacttt
    80581 ttttagataa taaatctctc atgaatatct ttctctcttt ataaattatc ggattaaacc
    80641 tcttgcaatt ataccacaaa gaataggtat agcatgatat aacgactttt cctaaaatct
    80701 tttatttcgt ataataacac tacggagaca atatataaac aattttctta ttttaccgtc
    80761 tattgaggg
//
LOCUS       DBJKQU010000004        79047 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.004, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000004 DBJKQU010000000
VERSION     DBJKQU010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 79047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79047
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.004"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            480..1766
                     /locus_tag="ACSUUC_000278"
     CDS             480..1766
                     /locus_tag="ACSUUC_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HHQ8053576.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYISTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            1781..2092
                     /locus_tag="ACSUUC_000279"
     CDS             1781..2092
                     /locus_tag="ACSUUC_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HHQ8053577.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            2338..3066
                     /locus_tag="ACSUUC_000280"
                     /pseudo
     CDS             2338..3066
                     /locus_tag="ACSUUC_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
     gene            3456..4292
                     /locus_tag="ACSUUC_000281"
     CDS             3456..4292
                     /locus_tag="ACSUUC_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053578.1"
                     /translation="MNVSKHYGHSIILKDINFALNKGEIVGLVGRNGVGKSTLMKILV
                     QNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLANLYGVDYNQERFRSLIQEL
                     DLTQSINKKVKTYSLGTKQKLALLLTLVTKPDILILDEPTNGLDIESSQIVLAVLKKL
                     ALNENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRD
                     IFITKQEFGDIVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNR
                     SK"
     gene            4308..5036
                     /locus_tag="ACSUUC_000282"
     CDS             4308..5036
                     /locus_tag="ACSUUC_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8053579.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLGLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            5422..5631
                     /locus_tag="ACSUUC_000283"
     CDS             5422..5631
                     /locus_tag="ACSUUC_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHQ8053580.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            5621..6109
                     /locus_tag="ACSUUC_000284"
     CDS             5621..6109
                     /locus_tag="ACSUUC_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HHQ8053581.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            6225..7685
                     /locus_tag="ACSUUC_000285"
     CDS             6225..7685
                     /locus_tag="ACSUUC_000285"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HHQ8053582.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGAQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            7682..8506
                     /gene="nadE"
                     /locus_tag="ACSUUC_000286"
     CDS             7682..8506
                     /gene="nadE"
                     /locus_tag="ACSUUC_000286"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HHQ8053583.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            8856..9407
                     /locus_tag="ACSUUC_000287"
     CDS             8856..9407
                     /locus_tag="ACSUUC_000287"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8053584.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWA
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            10452..10679
                     /locus_tag="ACSUUC_000288"
     CDS             10452..10679
                     /locus_tag="ACSUUC_000288"
                     /inference="COORDINATES: protein motif:HMM:NF019142.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HHQ8053585.1"
                     /translation="MKVPAESKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVT
                     TITYNVDGKSGQVTESTLSQKKDSQTRVVKK"
     gene            10868..11257
                     /locus_tag="ACSUUC_000289"
     CDS             10868..11257
                     /locus_tag="ACSUUC_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HHQ8053586.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(11918..12946)
                     /gene="queA"
                     /locus_tag="ACSUUC_000290"
     CDS             complement(11918..12946)
                     /gene="queA"
                     /locus_tag="ACSUUC_000290"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HHQ8053587.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            13097..13804
                     /locus_tag="ACSUUC_000291"
     CDS             13097..13804
                     /locus_tag="ACSUUC_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HHQ8053588.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            13944..14120
                     /gene="rpsU"
                     /locus_tag="ACSUUC_000292"
     CDS             13944..14120
                     /gene="rpsU"
                     /locus_tag="ACSUUC_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HHQ8053589.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            14250..15185
                     /gene="hprK"
                     /locus_tag="ACSUUC_000293"
     CDS             14250..15185
                     /gene="hprK"
                     /locus_tag="ACSUUC_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HHQ8053590.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            15178..15966
                     /gene="lgt"
                     /locus_tag="ACSUUC_000294"
     CDS             15178..15966
                     /gene="lgt"
                     /locus_tag="ACSUUC_000294"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HHQ8053591.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            15967..16350
                     /locus_tag="ACSUUC_000295"
     CDS             15967..16350
                     /locus_tag="ACSUUC_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HHQ8053592.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            16366..16755
                     /locus_tag="ACSUUC_000296"
     CDS             16366..16755
                     /locus_tag="ACSUUC_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HHQ8053593.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            16839..17969
                     /gene="hemW"
                     /locus_tag="ACSUUC_000297"
     CDS             16839..17969
                     /gene="hemW"
                     /locus_tag="ACSUUC_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HHQ8053594.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLNAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            17974..18711
                     /locus_tag="ACSUUC_000298"
     CDS             17974..18711
                     /locus_tag="ACSUUC_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HHQ8053595.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            18722..19495
                     /locus_tag="ACSUUC_000299"
     CDS             18722..19495
                     /locus_tag="ACSUUC_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HHQ8053596.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            19485..20102
                     /locus_tag="ACSUUC_000300"
     CDS             19485..20102
                     /locus_tag="ACSUUC_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HHQ8053597.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            20314..20715
                     /locus_tag="ACSUUC_000301"
     CDS             20314..20715
                     /locus_tag="ACSUUC_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HHQ8053598.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            20715..20993
                     /locus_tag="ACSUUC_000302"
     CDS             20715..20993
                     /locus_tag="ACSUUC_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HHQ8053599.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            20983..21756
                     /locus_tag="ACSUUC_000303"
     CDS             20983..21756
                     /locus_tag="ACSUUC_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HHQ8053600.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            21757..23061
                     /locus_tag="ACSUUC_000304"
     CDS             21757..23061
                     /locus_tag="ACSUUC_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HHQ8053601.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            23635..24513
                     /gene="pstS"
                     /locus_tag="ACSUUC_000305"
     CDS             23635..24513
                     /gene="pstS"
                     /locus_tag="ACSUUC_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HHQ8053602.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            24513..25430
                     /gene="pstC"
                     /locus_tag="ACSUUC_000306"
     CDS             24513..25430
                     /gene="pstC"
                     /locus_tag="ACSUUC_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HHQ8053603.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            25420..26304
                     /gene="pstA"
                     /locus_tag="ACSUUC_000307"
     CDS             25420..26304
                     /gene="pstA"
                     /locus_tag="ACSUUC_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HHQ8053604.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            26315..27118
                     /gene="pstB"
                     /locus_tag="ACSUUC_000308"
     CDS             26315..27118
                     /gene="pstB"
                     /locus_tag="ACSUUC_000308"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HHQ8053605.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            27131..27889
                     /gene="pstB"
                     /locus_tag="ACSUUC_000309"
     CDS             27131..27889
                     /gene="pstB"
                     /locus_tag="ACSUUC_000309"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HHQ8053606.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            27901..28554
                     /gene="phoU"
                     /locus_tag="ACSUUC_000310"
     CDS             27901..28554
                     /gene="phoU"
                     /locus_tag="ACSUUC_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HHQ8053607.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            28711..29526
                     /locus_tag="ACSUUC_000311"
     CDS             28711..29526
                     /locus_tag="ACSUUC_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHQ8053608.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(29546..30817)
                     /locus_tag="ACSUUC_000312"
     CDS             complement(29546..30817)
                     /locus_tag="ACSUUC_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HHQ8053609.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            30959..31690
                     /gene="budA"
                     /locus_tag="ACSUUC_000313"
     CDS             30959..31690
                     /gene="budA"
                     /locus_tag="ACSUUC_000313"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HHQ8053610.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            31700..32453
                     /locus_tag="ACSUUC_000314"
                     /pseudo
     CDS             31700..32453
                     /locus_tag="ACSUUC_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            32565..33515
                     /gene="murB"
                     /locus_tag="ACSUUC_000315"
     CDS             32565..33515
                     /gene="murB"
                     /locus_tag="ACSUUC_000315"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HHQ8053611.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            33574..34731
                     /locus_tag="ACSUUC_000316"
     CDS             33574..34731
                     /locus_tag="ACSUUC_000316"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053612.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            34712..35518
                     /locus_tag="ACSUUC_000317"
     CDS             34712..35518
                     /locus_tag="ACSUUC_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8053613.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            35515..36288
                     /locus_tag="ACSUUC_000318"
     CDS             35515..36288
                     /locus_tag="ACSUUC_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8053614.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            36285..37355
                     /locus_tag="ACSUUC_000319"
     CDS             36285..37355
                     /locus_tag="ACSUUC_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHQ8053615.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            37616..37855
                     /locus_tag="ACSUUC_000320"
     CDS             37616..37855
                     /locus_tag="ACSUUC_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053616.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            38130..38615
                     /locus_tag="ACSUUC_000321"
     CDS             38130..38615
                     /locus_tag="ACSUUC_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HHQ8053617.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            38637..41255
                     /gene="alaS"
                     /locus_tag="ACSUUC_000322"
     CDS             38637..41255
                     /gene="alaS"
                     /locus_tag="ACSUUC_000322"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HHQ8053618.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GNIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQLSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGR
                     NQAKIQELLDAVAGKL"
     gene            complement(41345..42799)
                     /locus_tag="ACSUUC_000323"
     CDS             complement(41345..42799)
                     /locus_tag="ACSUUC_000323"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HHQ8053619.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFIDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            42978..43727
                     /locus_tag="ACSUUC_000324"
     CDS             42978..43727
                     /locus_tag="ACSUUC_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053620.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCNRIAILKKGHLIYCGSVEN
                     LRKDHPDQSLESIYLSLAGRKEEVADASQGH"
     gene            43708..45342
                     /locus_tag="ACSUUC_000325"
     CDS             43708..45342
                     /locus_tag="ACSUUC_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053621.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLFMFINIAFRFPFEEMPSFFSTMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTRVFRKYRSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEDKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            46026..47189
                     /locus_tag="ACSUUC_000326"
     CDS             46026..47189
                     /locus_tag="ACSUUC_000326"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HHQ8053622.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTTYRLFNQ
                     EGDGFGGLTVDLYGNYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLTMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            47186..47863
                     /gene="aroD"
                     /locus_tag="ACSUUC_000327"
     CDS             47186..47863
                     /gene="aroD"
                     /locus_tag="ACSUUC_000327"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HHQ8053623.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            47853..48707
                     /locus_tag="ACSUUC_000328"
     CDS             47853..48707
                     /locus_tag="ACSUUC_000328"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HHQ8053624.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            48726..49793
                     /gene="aroB"
                     /locus_tag="ACSUUC_000329"
     CDS             48726..49793
                     /gene="aroB"
                     /locus_tag="ACSUUC_000329"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HHQ8053625.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            49803..50969
                     /gene="aroC"
                     /locus_tag="ACSUUC_000330"
     CDS             49803..50969
                     /gene="aroC"
                     /locus_tag="ACSUUC_000330"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HHQ8053626.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            50979..52082
                     /locus_tag="ACSUUC_000331"
     CDS             50979..52082
                     /locus_tag="ACSUUC_000331"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HHQ8053627.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            52093..52431
                     /locus_tag="ACSUUC_000332"
     CDS             52093..52431
                     /locus_tag="ACSUUC_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HHQ8053628.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            52523..53806
                     /gene="aroA"
                     /locus_tag="ACSUUC_000333"
     CDS             52523..53806
                     /gene="aroA"
                     /locus_tag="ACSUUC_000333"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HHQ8053629.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITVQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            53799..54275
                     /locus_tag="ACSUUC_000334"
     CDS             53799..54275
                     /locus_tag="ACSUUC_000334"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HHQ8053630.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQRDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            54272..55120
                     /gene="pheA"
                     /locus_tag="ACSUUC_000335"
     CDS             54272..55120
                     /gene="pheA"
                     /locus_tag="ACSUUC_000335"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HHQ8053631.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWLLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            55117..56391
                     /gene="psr"
                     /locus_tag="ACSUUC_000336"
     CDS             55117..56391
                     /gene="psr"
                     /locus_tag="ACSUUC_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HHQ8053632.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFVYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            56670..57515
                     /locus_tag="ACSUUC_000337"
     CDS             56670..57515
                     /locus_tag="ACSUUC_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HHQ8053633.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVVFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            57505..58608
                     /locus_tag="ACSUUC_000338"
     CDS             57505..58608
                     /locus_tag="ACSUUC_000338"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHQ8053634.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            58610..59596
                     /locus_tag="ACSUUC_000339"
     CDS             58610..59596
                     /locus_tag="ACSUUC_000339"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHQ8053635.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            59612..61045
                     /locus_tag="ACSUUC_000340"
     CDS             59612..61045
                     /locus_tag="ACSUUC_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HHQ8053636.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            61074..62108
                     /locus_tag="ACSUUC_000341"
     CDS             61074..62108
                     /locus_tag="ACSUUC_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HHQ8053637.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            62250..62987
                     /gene="mecA"
                     /locus_tag="ACSUUC_000342"
     CDS             62250..62987
                     /gene="mecA"
                     /locus_tag="ACSUUC_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HHQ8053638.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFAEDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            63137..64423
                     /locus_tag="ACSUUC_000343"
     CDS             63137..64423
                     /locus_tag="ACSUUC_000343"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HHQ8053639.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            64425..65294
                     /gene="thrB"
                     /locus_tag="ACSUUC_000344"
     CDS             64425..65294
                     /gene="thrB"
                     /locus_tag="ACSUUC_000344"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HHQ8053640.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGSTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            65634..66572
                     /gene="msrB"
                     /locus_tag="ACSUUC_000345"
     CDS             65634..66572
                     /gene="msrB"
                     /locus_tag="ACSUUC_000345"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HHQ8053641.1"
                     /translation="MTEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            66630..68354
                     /locus_tag="ACSUUC_000346"
     CDS             66630..68354
                     /locus_tag="ACSUUC_000346"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053642.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLIPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVKLFKGTIRSNLTLGLNQEVSDQKLWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            68356..70104
                     /locus_tag="ACSUUC_000347"
     CDS             68356..70104
                     /locus_tag="ACSUUC_000347"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053643.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFVKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            70406..71665
                     /locus_tag="ACSUUC_000348"
     CDS             70406..71665
                     /locus_tag="ACSUUC_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HHQ8053644.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    71741..71876
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            71915..72415
                     /gene="rplJ"
                     /locus_tag="ACSUUC_000349"
     CDS             71915..72415
                     /gene="rplJ"
                     /locus_tag="ACSUUC_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HHQ8053645.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            72491..72859
                     /gene="rplL"
                     /locus_tag="ACSUUC_000350"
     CDS             72491..72859
                     /gene="rplL"
                     /locus_tag="ACSUUC_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HHQ8053646.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            73046..73216
                     /locus_tag="ACSUUC_000351"
     CDS             73046..73216
                     /locus_tag="ACSUUC_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053647.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            73216..73467
                     /locus_tag="ACSUUC_000352"
                     /pseudo
     CDS             73216..73467
                     /locus_tag="ACSUUC_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            73478..73818
                     /locus_tag="ACSUUC_000353"
                     /pseudo
     CDS             73478..73818
                     /locus_tag="ACSUUC_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            73811..74191
                     /locus_tag="ACSUUC_000354"
     CDS             73811..74191
                     /locus_tag="ACSUUC_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HHQ8053648.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            74204..74347
                     /locus_tag="ACSUUC_000355"
     CDS             74204..74347
                     /locus_tag="ACSUUC_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053649.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            74440..75027
                     /locus_tag="ACSUUC_000356"
     CDS             74440..75027
                     /locus_tag="ACSUUC_000356"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHQ8053650.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            75229..75366
                     /locus_tag="ACSUUC_000357"
     CDS             75229..75366
                     /locus_tag="ACSUUC_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HHQ8053651.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            75545..76624
                     /locus_tag="ACSUUC_000358"
     CDS             75545..76624
                     /locus_tag="ACSUUC_000358"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053652.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSEIERVYANLWTVA"
     gene            76569..77546
                     /locus_tag="ACSUUC_000359"
     CDS             76569..77546
                     /locus_tag="ACSUUC_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHQ8053653.1"
                     /translation="MSFILKLRGFTLTYGQWRKEFQSRFFPVHYYGLNFNQGIAFSDL
                     AILWSYQQLAKKVKNFKFDDYYEIRTQVINEAVNNFKKSSLSGLFDGKIGTIWLIYEF
                     GEIDRAVELFTTHFIEIFENSQNKNLYSGQVSIDFSFKSPFRVLLTGTSGSGKTTILN
                     LINGSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQII
                     EVLKKVNLYEELEKIDILNYQCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISAN
                     LDNDNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            77561..78301
                     /locus_tag="ACSUUC_000360"
     CDS             77561..78301
                     /locus_tag="ACSUUC_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053654.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            78304..>79047
                     /locus_tag="ACSUUC_000361"
     CDS             78304..>79047
                     /locus_tag="ACSUUC_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHQ8053655.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCF"
BASE COUNT        23369 a        14340 c        17585 g        23753 t
ORIGIN      
        1 taaattcttt gagctttttt ctttttaaat attgattgtt tctaaaagtt ctagtaatat
       61 tgctatttct catttttcca aatatgttat tcaacttatt agctacgtct ctattcatat
      121 ttgggtataa aacaaaaaat caattctaac agttttatat cagaataata aataaaaaag
      181 cgatattcta gactgtatca atccttttcc attataggag caacagagtg ggagtagtca
      241 tctaaggact aatttatgta tttttacgag tcagtatctt tggatactgg tttttacttt
      301 tctagacttt ttgactactt gttaaaactg ggataatttt cgactgttta acagttatta
      361 tgcaaagtct aaaagattag aattgtcaaa acaatccgtc taggcttgat tttatccttt
      421 atttactata aaatgagaag gaaaaatgtc aaacttttat attgcaaata ggagaaatta
      481 tgacaaaaac attaaaacgt cctgaggttt tatcacctgc agggacttta gagaagctaa
      541 aggtagctgt tcagtatgga gcagatgctg tctttatcgg tggtcaggcc tatggtcttc
      601 gtagccgtgc cggaaacttt actttcgaac agatggaaga aggcgtgcag tttgcggcca
      661 agtatggtgc caaggtctat gtagcggcta atatggttat gcacgaagga aatgaagctg
      721 gtgctggtga gtggttccgt aaactgcgtg atatcgggat tgcagcagtt atcgtatctg
      781 acccagcctt gattatgatt gcagctactg aagcaccagg ccttgaaatc cacctttcta
      841 cccaagccag tgccactaac tatgaaaccc ttgagttctg gaaagagcta ggcttgactc
      901 gtgtcgtttt agcgcgtgag gtttcaatgg aagaattagc tgaaatccgc aaacgtacag
      961 atgttgaaat tgaagccttt gtccatggag ctatgtgtat ttcatactct ggacgttgta
     1021 ctctttcaaa ccacatgagt atgcgtgatg ccaaccgtgg tggatgttct cagtcatgcc
     1081 gttggaaata cgacctttac gatatgccat ttgggaaaga acgtaagagt ttgcagggtg
     1141 agattccaga agaattttca atgtcagccg ttgacatgtc tatgattgac cacattccag
     1201 atatgattga aaatggtgtg gacagtctaa aaatcgaagg acgtatgaag tctattcact
     1261 acatatcaac agtaaccaac tgctacaagg cggctgtgga tgcctatctt gaaagtcctg
     1321 aaaagtttga agctatcaaa caagacttgg tggacgagat gtggaaggtt gcccaacgtg
     1381 aattggcaac aggtttctac tacggtatac catctgaaaa tgagcagttg tttggtgctc
     1441 gccgtaaaat tcctgagtac aagtttgtcg ctgaagtggt ttcttatgat gatgcggtac
     1501 aaacagcaac tattcgtcaa cgaaacgtca ttaacgaagg ggaccaagtt gagttttatg
     1561 gtccaggttt ccgtcatttt gaaacctata ttgaagattt gcatgatgcc aaaggcaata
     1621 aaatcgaccg cgctccaaat ccaatggaac tattgactat taaagtccca caacccgttc
     1681 aatcaggaga catggttcgt gcattaaaag aaggactcat caatttttat aaggaagatg
     1741 gaaccagcgt cacagttcga gcttaagaaa ggaaaaggaa atgatagagg cacagggttt
     1801 cttagtggat aagcaaacaa gatgcattca ttaccatagc aagctggata ttattgcttt
     1861 acaatgctat gattgtaaaa agtattatgc ttgttatcgg tgtcatgatt cattagaaaa
     1921 tcaccctttt gagccgtatc ccttatcttt gatacaggat aagcctattt tatgtggtgt
     1981 ttgtctaaaa ctactaacat ataagcaata taaagaaagt ttaagttgcc ccttttgttt
     2041 ttctcgcttt aatccaggtt gccaaaatca taaggaacgc tattttaaat agcaaatcat
     2101 ctagttttga agtaggagaa aactcaattc caagagaaaa tgaagtaaat cttcccacaa
     2161 taaaacgcat aatatcaaga ttgttcaata cctgatacta tgcgttttta agattttaaa
     2221 gacttttttc ctttatctgg tattttgact acttgttaaa actgggttaa ttttcaactg
     2281 tttaacagtt attatgcaaa gtctaaaaga ttagaattgt caaaacaatc cgtctagagt
     2341 atgcgtgatg ccaaccgtgg tggatgttct cagtcatgcc gttggaagta cgacctttac
     2401 gatatgccat ttgggaaaga acgtaagagt ttgcagggtg agattccaga agaattttca
     2461 atgtcagccg ttgacatgtc tatgattgac cacattccag atatgattga aaatggtgtg
     2521 gacagtctaa aaatcgaagg acgtatgaag tctattcact acatatcaac agtaaccaac
     2581 tgctacaagg cggctgtgga tgcctatctt gaaagtcctg aaaagtttga agctatcaaa
     2641 caagacttgg tggacgagat gtggaaggtt gcccaacgtg aactggctac aggattttac
     2701 tatggtacac catctgaaaa tgagcagttg tttggtgctc gtcgtaaaat tcctgagtac
     2761 aagtttgtcg ctgaagtggt ttcttatgat gatgcggcac aaacagcaac tattcgtcaa
     2821 cgaaatgtca ttaacgaagg ggaccaagtt gagttttatg gtccaggttt ccgtcatttt
     2881 gaaacctata ttgaagattt gcatgatgcc aaaggcaata aaatcgaccg cgctccaaat
     2941 ccaatggaac tattgactat taaagtccca caacctgttc aagctggaga catggttcga
     3001 gctcttaaag aggggcttat caatctttat aaggaagatg gaaccagcgt cacagttcgt
     3061 gcttaatgta gttgtttagt tttaaaaaat tatgcaaagc tccatataca acacttaaac
     3121 gagattaaag aatggcgaaa tcccttgatg cgcaagggat tagctgtctt ttttattttt
     3181 taagtgataa agtcggagct taggtatcaa agcctatcaa attaaacaaa gaagcgatgt
     3241 cttagatatt ttgaaaaaaa ttaataagca gaaaactctc tattattttg ttgtagagag
     3301 ttttttgtta ataaaatttt acaaaatgac atttatatat tgcattaagt tagatatatg
     3361 atataatgtt gttaaaaaga ggcgcaactt tttaaactca ataagaatca aagagcaaac
     3421 cgagaatatt aatggaggaa taaaaaatgt aagttataaa tgtaagtaag cattatggtc
     3481 attcaatcat tctcaaagat ataaattttg cacttaacaa gggtgaaatt gttggtctag
     3541 tagggagaaa cggagttggt aagagtacat tgatgaaaat tcttgttcag aataatcaac
     3601 cgacttcagg gaatattata agtagtgata atgttgggta tttaattgaa gaaccaaaat
     3661 tatttttatc taaaacaggt ttagagaatt taaaatatct ggcaaactta tatggtgttg
     3721 actacaatca agaaagattt agaagtttga tccaagagtt agatttgact cagtctatta
     3781 ataaaaaagt aaagacctat tctttgggta caaaacaaaa attagctttg cttctaactc
     3841 tcgttacgaa acctgatata ttgattttag atgaaccgac taatggttta gatattgaat
     3901 catcacaaat agttttagcg gttctaaaaa aattagcttt aaatgaaaac gtgggaattt
     3961 taatatcgag tcataaatta gaagacattg aagaaatttg tgagagagtt cttttcttgg
     4021 agaacgggct tttgacattt caaaaagtag gaaaagatag tcataatttc ttgtttgaga
     4081 tagctttttc atcagctaca gatagagaca ttttcattac caaacaagaa tttggggata
     4141 ttgttcagga agagggattg agaattacta tgtctgggaa tattcaaagt agtgagcttt
     4201 ttaaattttt taacgaaaac tctattaaag tagttgattt tgaaactaaa aaagagacgc
     4261 ttaaagatat ttacctaaat cgttcaaaat aaaggaaggt tataatcatg aaattaaata
     4321 aattgaattt tcttaaggaa aatataagaa atttatattc atcaggcgta atatatctcg
     4381 gtttgcttat ctcgtttata ccgccgatat tgcttacatt ctttattcta aagactcaag
     4441 ggacatcgct tggtattaag catatttcaa acttttatgc tatgctcggt atgttaatgg
     4501 ctgttataca tgctaatcga gtcattagta gagatttttc ccacaatacg gtaagtttgt
     4561 tttataatca acagaagaat cggatgattt acgtcttgtc taattttcta tatgccatct
     4621 cagtttccat tatttatgct ttgaatggca ttgtgttact agtcatagta agtaaattgg
     4681 gtattccagg tgatttagga ttagatttta tagtagctat tgtagtcaat acaattttgt
     4741 tagtcctgtt ttattttcta ttatcttaca ttttctattt atacaaattg aaaagtggct
     4801 tggtatttgg tattttagta gctttactac tctttatccc taatatatta aatacgatga
     4861 tgatgaatac tagtaatgat ttgtttatca aagcaattga acttcttcct ttttattctt
     4921 tacctgtatt tgtggcttca aatacgatgt ctattagtca gtatcttgtg gtaatcacta
     4981 caatcatttt attgtacttt ttcactctca agaaaagcaa gaagtattca ttttagtttc
     5041 atttagtatt attttgcata cctaaaatac aataaaaaaa tcagtcatct tggtatgctc
     5101 ctgctttcac tattcaacac gtttttgact tatactaggc tcatttccaa aagcattata
     5161 taatagtgat atgaaaccaa ctaaactaaa caagaaatat aagcaataaa aactcgttta
     5221 aaagattcta ctaaagctaa tactaaataa aaataaaaga gtaaactagg aagtttattt
     5281 caaacaacct aaaatactga ttttcggctg aagataatac tggagtgcaa attaatgggg
     5341 ttataataaa tagctgatag cttgtgttgg ttttggattt tttaagagta gatgagtatt
     5401 aaaactataa ggaggacgaa ggtggctaaa aatttaaaat taaaattagc tcgggtagag
     5461 cgtgatttaa cacaaggtca actggcagag gctgtcgggg tgacacgcca gactattggt
     5521 ttgatagagg cgggaaaata caatcccagt ctctcgctct gccagtctat ttgcagatgt
     5581 ttagggaaaa ccctagacca actattttgg gaggaagaag atgaaaaata gattttatta
     5641 ttatcaatta ctagacgaaa gagaagaaca actgttcaat aaagcgggat ctgaaagttt
     5701 ctatatctgc attgctttgt cgctcctatc ttatatcatt tcagtattag caccaagcct
     5761 ttttaattct aatatgctgc taatcgttat catcataggg acattttact ttttcaatcg
     5821 cgcccgttat ctgggagtga cctactatag tcgttttcat tttacgattt tgggttgttt
     5881 tttcctaacc ttggctatta cggctctttt gatgttgcag aattatcaat tcaacataga
     5941 aatttatcag cacaatcctt tgaattttaa atacctgtct gcttgggtca ttacttatgt
     6001 catttacctt ccgtgggtct ttattggcaa tcttggtctt aagagctatg gcgaatgggc
     6061 tcagaaaaaa tttgaacaag atatggatga attggagagt ggagaatagc ttgttactct
     6121 tttctcaatc cagctaaaat gtgatataat agtactaatt tattggaata catgaaagtt
     6181 cttgaaaatt ttcatgtgtt tctagctaag gaagtaggaa aagtatgtat ccagatgata
     6241 gtttgacatt gcacacggac ttgtaccaga tcaacatgat gcaggtttac tttgaccaag
     6301 ggattcacaa taagaaggcg gtctttgagg tgtatttccg ccaacagcct tttaagaacg
     6361 gctatgcggt ttttgcaggt ttggaaagaa ttgtgaacta tcttgaagac ttgcgttttt
     6421 cagatagtga tatagcctat ttggagtcgc ttggttatca tggggcgttc ttggattacc
     6481 ttcgcaattt caagttggag ttgaccgttc gttctgccca agaaggggat ttggtttttg
     6541 ctaatgaacc gattgtgcag gtggaaggac ctctagccca atgtcagttg gtcgaaacgg
     6601 ctcttttgaa catcgtcaac taccagacct tggtggcgac gaaggcagct cgtattcgtt
     6661 cggttatcga agatgaaccc ttgatggagt ttgggacacg tcgggctcaa gaaatggatg
     6721 cggccatctg gggaacacgc gcagcggtga ttggtggggc caatggaacc agcaacgtgc
     6781 gtgcgggtaa gctctttgac attcctgttt tgggaaccca tgcccatgcc ttggtacagg
     6841 tttatggcaa tgactatgaa gctttcaagg cttacgctgc gacccacaaa aattgtgtct
     6901 ttcttgtgga cacctatgac acccttcgca tcggtgtacc agctgccatt caggtggcgc
     6961 gtgagctggg tgctcagatt aactttatgg gtgtgcggat tgactctggg gatattgcct
     7021 acatttctaa gaaagtccgt cagcaactgg acgaggctgg atttacagag gctaagattt
     7081 atgcttctaa tgatttggac gaaaatacta tcctcaatct caagatgcaa aaggccaaga
     7141 ttgatgtctg gggcgtgggt accaagctga ttacagctta tgaccagcca gctcttggtg
     7201 cagtttacaa gattgttgca atcgaagatg aaactggtca gatgcgcaat acgattaagc
     7261 tgtctaataa tgctgaaaaa gtttctacgc caggtaagaa gcaggtgtgg cgcattacca
     7321 gtcgtgaaaa aggcaagtca gaaggtgact acatcactta tgatggtgtg gatattagcg
     7381 acatgacaga aatcaagatg ttccatccga cctatacata catcaagaag acggttcgta
     7441 attttgatgc cgttcctctc ttggtggata tcttcaaaga aggaatatta gtttacaact
     7501 tgcctagttt gactgacatt caggattatg cccgtaagga atttgacaag ttgtgggatg
     7561 agtataagcg tgtgctcaat ccgcagcact atccagtgga tttggcgcgt gacgtatggc
     7621 aagataagat ggacttgatt gataagatgc gcaaggaagc ccttggtgaa ggagaagaag
     7681 aatgagtttg caagaaacga ttatccaaga gctgggtgtc aaaccagtga ttgatgccca
     7741 ggaagaaatc cgtcgttcta ttgatttctt aaaaagatat ctgaaaaaac atcccttcct
     7801 aaaaaccttt gtactaggga tttctggggg acaagactca accttggcag gacgtttggc
     7861 gcaattagct atggaagaac tgcgagctga aacgggagac gatagctaca aatttatcgc
     7921 tgtccgcctg ccatacggag tgcaagctga tgaagcagat gctcaaaaag ccctagcctt
     7981 catccagcca gatgtcagct tggttgtgaa tatcaaggaa tcagctgatg ccatgacagc
     8041 tgcagttgaa gcgacaggta gtcctgtttc agacttcaac aaggggaata tcaaggcacg
     8101 ttgccgtatg attgctcagt atgcccttgc tggttcccat agcggagcgg tcattggaac
     8161 agaccacgcc gcagaaaata tcacaggttt ctttaccaag tttggtgacg gcggtgcgga
     8221 tattctccct ctttaccgcc tcaataaacg ccaaggaaaa cagctcttgc agaaacttgg
     8281 cgcagagcca gccctttatg aaaaaatccc aacggcagac ctagaagaag ataaaccagg
     8341 cctagctgac gaagtcgcac ttggagtcac ctacgcagag attgacgact acctagaagg
     8401 caaaacaatc agcccagaag ctcaagcgac cattgaaaac tggtggcaca aaggccaaca
     8461 caaacgccac ttacccatca ccgtatttga tgacttttgg gagtaaaaag gtccggggga
     8521 cctttttagc ttcttgccct gaaattaaaa agcaagaaaa acctccactg gaggttttca
     8581 gcctctcatc ttgaaataag aaagtgagag aaggtccggg ggatcttgaa cctcgagttt
     8641 agaaataaga aaatgaggca gattcggtaa ctcgaagagt tcgatttcat cgtcttaccc
     8701 ctgcaacgat gactaggttt gaaaaagctt gctagatcgc atttcaaacc aggcagcgac
     8761 tgcgtcaaga aattagaaga caaactcgtt ttctagctgt tactgagttg agccttttta
     8821 ctacgagcat agaaataagg aagtgaggta gcatcatgaa atctattggt acgcaaatat
     8881 tacagacaga acgtttgatt ttaagaagat ttgtggagag tgatgcagaa gccatgtttc
     8941 aaaattgggc ttcatccgct gagaatctga cctatgttac ctgggctccc catcctgatg
     9001 tcgaaatcac tcgaaactcg attcgcaatt gggttgcttc ctatactaat ctcaactatt
     9061 acaaatgggc catttgtcta aaagaaaacc cagagcaagt gataggagat atcagcatcg
     9121 ttaagataga cgaggctgat ttaagctgtg aaatcggcta tgtgctaggc aaggcttact
     9181 ggggacatgg tatgatgaca gaggccttga aagctgtctt ggacttttgt tttactcaag
     9241 caggttttca aaaggtcaga gcacgttatg ccagtctcaa cccagcttca ggtcgtgtca
     9301 tggaaaaggc tggaatgtcc tatctacaaa ccattgttaa tggtgtagag agaaaaggct
     9361 atcttgcgga tcttatttat tatggtataa gtagggaaga atgttgaatt ctattttctg
     9421 tttctatcga agtcaactat ttattgtaaa tataataatt agcattccaa gtttatttgc
     9481 aattttaaaa tagcatattg attagtacaa gacagatgtt ctagttcctt ctttaatctg
     9541 gtttagtatt agttaaaaaa tcgctttaag cttgtaacta agagggagct aatcgactag
     9601 attctccagc cgaacaggtg gtaatgtact ttttatagtg taatcctagc tgttgttaaa
     9661 tttaaaatag aatcctctat cgagttaggg aattaaattc aaccaatttt atttatgttt
     9721 tttctatcaa attatctaat attaaaatag tctcattctg atgagaaaac tattctattt
     9781 atactgcatc gttgtgtaag gaatgatgaa agatgagtga aaattatcaa gttggaatgt
     9841 ttgtatctaa atatattagc atgtatttag atcagatgtc tgcaatcctt tatatatgag
     9901 attgattacg atatagttaa agtgttagtt caatagtaaa tatatcattc taagtctatt
     9961 ttatatataa agtatattgt ttaacgtttg atagaaaaga tgctatacta gaagtaggat
    10021 gtaatggcaa aatctaatac taataagcgc tatgcaatac gtaaactcgg aaagattttt
    10081 ggttctgcgg taatcgggct aactttattt ttaggaggaa tctgaataca agttttgctc
    10141 atgctgctga tgggattcaa tatgtcagag atgatactag agataaagaa gagggaatag
    10201 agtatgatga cgctgacaat ggggatatta ttgtaaaagt agcgactaaa cctaaggtag
    10261 taaccaagaa aatttcaagt acgcgaattc gttttgaaaa agatgaaaca aaataccgta
    10321 gtgaaaatcc tgttacaatt gacggagagg atggctatgt aaccacgaca aggacctacg
    10381 atgttaatct agagactggt catgttaccg aacaggttac tgttgataga aaagaagcca
    10441 cggatacagt tatcaaagtt ccagctgaaa gcaaggttga agaagttctt gttccatgtg
    10501 ctactaaata tgaagcagac aatgaccttt ctgcaggaca ggagcaagag attactctag
    10561 gaaagaatgg gaaaacagtt acaacgataa cttataatgt agatggaaag agtggacaag
    10621 taactgagag tactttaagt caaaaaaaag actctcaaac aagagttgtt aaaaaatgaa
    10681 ccaagcccca agttcttgtc caagaaattc caatcgaaac agaatatctc gatggcccaa
    10741 ctcttgataa aagtcaagaa gtagaagaag taggagaaat tggtaaatta ctcttactac
    10801 aatctatact gtagatgaac gtgatggaac aattgaagaa actacttctc gtcaaattac
    10861 taaagagatg gtaaaaagac gtataaggag agggacgaga gaacctgaaa aagttgttgt
    10921 tcctgagcaa tcatctattc cttcgtatcc tgtatctgtt acatctaacc aaggaacaga
    10981 tgtagcagta gaaccagcta aagcagttgc tccaacaaca gactggaaac aagaaaatgg
    11041 tatgtggtat ttttataata ctgatggttc catggcaaca ggttgggtac aagttaatgg
    11101 ttcatggtac tacctcaaca gcaacggttc tatgaaagtc aatcaatggt tccaagttgg
    11161 tggtaaatgg tattatgtaa atgcatcggg tgagttagcg gtcaatacaa gtatagatgg
    11221 ctatagagtc aatgataatg gtgaatgggt gcgttaacag attcctccct gcgacaaaat
    11281 tgataatagt atgtctgaat atataattat atataaaaag ctatagataa ggtcatctta
    11341 tagcgactat aaaaaagtga acaagcctag tcttctgtac attagaattc agatttgttc
    11401 actttttgtt taatactcaa tgaaaatcaa agagcaaact agaaaactag tcgcaggttg
    11461 ctcaaagtac tgctttgagg ttgtagatag aactgacgaa gtcagtcaca tatataatcc
    11521 aaggtgacgt tgacgcggtt tgaagagatt tttgaagagt ataagtcttt gattttgaga
    11581 ctaaggagag tcagggtcaa agtagtgaat gattctgaaa taactcataa tagtctcttg
    11641 agaggacaga taagagtaac aaatatggtg ctactcatgt gtcttgcatt ttgatttaca
    11701 aacagcgaag aaaatatagg aagctgaaat aaaatataga tgaatcaatt tggagagtca
    11761 acgcaatcta tggcaatatt ttcgaagcta gggggaagca ttttaatttc aatgtactag
    11821 gcgtcttcta cagctagcta gagtttcaat tgtagatgtt ctttgaaata atatcttagc
    11881 gatttattgg tattagaaga attagagaaa ttctttctca ataaataaac atggcgtcac
    11941 caaaactgaa gaagcggtag tgttcttgga tggcatggtg gtaggcatct aagactaatt
    12001 cacggcctgc aaaggcagaa accaacatga ccagagttga ttttggcaga tggaagttgg
    12061 ttgagaaggc atccacgacc ttccactcat acccaggttt gataaagata ttggtccaac
    12121 cagaatctgc ttggatttgc ccatcaaact tggaaccaat agtttccaag gtgcggatag
    12181 aagtggttcc gacagcgatg acgcgaccac cattttcttt gacagagcga agggtggcag
    12241 cagcttcctc agaaagttga tagaactctg agtgcatttc gtgttcgtcc agattatcca
    12301 cagaaacagg tctaaaggtt ccgagtccga catggagagt cagatagact agatgaacac
    12361 ccttagcttg gatttctgcc agcagttctt tggtgaagtg aagaccagca gtcggtgctg
    12421 cagcagagcc gctttccttg gcgtagacgg tttgataacg ttcacggtca tctaattttt
    12481 cgtggatata aggtggcaga ggcatttctc ccagactttc caagacttct aggaaaattc
    12541 cttggtattc aaagcggaca atgcgtcccc cgtgggtcaa ttcttctgta acgacagcgc
    12601 tgaggcggcc atcaccaaag ctgatacgag taccgacctt gaggcgtttg gcaggtttag
    12661 ccagaacttc ccactcgtct ccactagtgt tcttaaggag gagaagttcc acatgacctc
    12721 ctgtctccac tttttgacca tagaggcggg cagggagaac tcgggtgtcg ttcatgacaa
    12781 gggcatcacc aggttccagc atatcaataa tagagtggaa atgtttatct tgcatttctc
    12841 ctgtctcacg gttgacgatg aggagtttgg aggcatcacg tttttcaagg ggcgtttggg
    12901 caatcaattc ctctggcaag tggaaatcaa aatcagctgt attcatatat ttgttcattc
    12961 tttctaagtt ctaatcctat ccattataac acgtttcaag tttggacgct ctttttttag
    13021 aaattaaatc gttttcactt gacaaaaatt ggtctatacc atataataaa tatagacaga
    13081 aatggaggat gaaaagatga aagttattaa agttgaaaac caagttcaag gtggaaaagt
    13141 tgcttttgag attttgaagg aaaaattggc taatggagct caaactctag gacttgcgac
    13201 aggaagtagc ccacttgaat tttacaagga aattgttgag agtgaccttg atttttcaaa
    13261 tctaaccagt gtcaaccttg atgagtatgt gggccttgat ggggacaatc cacagtctta
    13321 tcgttacttc atgcaagaaa acttgttcaa ccaaaaacca tttaaagaaa gtttcttgcc
    13381 tcgtggtgtt aaggacaatg ctgaagctga agttgaacgc tacaaccaaa ttttggctga
    13441 ccatccagtt gacctccaaa tcttgggaat cggtcgcaat gggcatatcg gctttaatga
    13501 gcctggtact ccatttgaca gtcaaacgca tctagtagaa cttgaccagt ctactatcga
    13561 agccaatgca cgcttctttg ccaagattga agacgtccca acccaagcta tttcaatggg
    13621 gattaaaaac attttggatg ccaagtctat tattcttttt gcttacggtg agtcgaaagc
    13681 agaagccatt gccggaacag tatctggccc agtgactgag aacctacctg caagtagcct
    13741 ccaaaatcac cctgatgtaa ccatcatcgc agatgctgaa gcgcttagct tactcgaaaa
    13801 ataaaaaagc aatgttctat tgaacgcttt caactcttgt ataaatggaa gaaaaaatca
    13861 aaattaaacc gcatttttgc ttgacaatta ttccttttac gtgtagaatg aaatagatct
    13921 tgaacttgaa gggagtgaaa aaaatgtcta aaacagtagt acgtaagaat gaatctcttg
    13981 acgacgcact tcgccgtttc aaacgtgcgg ttactaaagc tggtactctt caagaaacac
    14041 gcaaacgtga attctatgaa aaaccttctg taaaacgtaa acgtaaatca gaagtagctc
    14101 gtaaacgtaa aaaattctaa ttgaaatgaa aggctagaga aatctagtcc tttttctttt
    14161 aaataaatac tccaaagcct gcaaaaatct gaaacttcct cctacaattt gatataatag
    14221 agagaagaac tcatttgaag gaggaaatga tgtcggtttt agtaaaagaa gtgattgaaa
    14281 agcttagact agacattgtc tatggtgaac cagaattgct tgaaaaggaa atcaatacag
    14341 cggatattac gcgacctggt cttgaaatga caggctattt tgactactat acaccagagc
    14401 ggattcaact tttggggatg aaggagtggt cttatctgat cagcatgcct tccaacagcc
    14461 gttatgaagt tttgaaaaaa atgtttctac ctgagacacc agcagtcatt gttgcccgtg
    14521 gtttggtggt tccagaggag atgttaaagg ctgctagaga atgtaagatt gctattttaa
    14581 ccagccgtgc agctaccagt cgtttatctg gagagttatc tagctatctg gattctcgtt
    14641 tggcagaacg taccagtgtg cacggtgtct tgatggatat ttatgggatg ggcgtcttga
    14701 ttcagggaga tagtggaatt ggtaagagcg agacaggtct tgagcttgtc aaacgtggtc
    14761 accgtttggt agccgatgac cgtgtcgata tctttgccaa ggatgagatt actctctggg
    14821 gtgaaccggc tgaaattttg aaacacttga ttgaaattcg tggggttggt attatcgatg
    14881 ttatgagtct ctacggtgcg agtgctgtca aggattcttc acaggttcag cttgctgtct
    14941 atttggaaaa ttacgatacg cataagacct ttgatcgtct tggaaacaat gcagaggaac
    15001 ttgaagtttc tggcgtagcc attcctcgta ttcgtattcc agttaaaaca ggtcgtaata
    15061 tctctgttgt gattgaggca gctgccatga attatcgtgc caaggaaatg ggctttgatg
    15121 ctacccgttt gttcgacgaa cgactgacaa gtctcatagc tcgaaatgag gtgcaaaatg
    15181 cttgatccaa ttgctattca actaggaccc ctagccattc gttggtatgc cttatgtatt
    15241 gtgacaggct tgattcttgc ggtttatttg accatgaaag aagcacctag aaagaagatc
    15301 ataccagacg atattttaga ttttatctta gtagcctttc ccttggctat tttaggagct
    15361 cgtctctact atgttatttt ccgatttgat tactatagtc agaatttagg agagattttt
    15421 gccatttgga atggtggttt ggccatttac ggtggtttga taactggggc tcttgtgctc
    15481 tatatctttg ctgaccgtaa actcatcaat acttgggatt ttctagatat tgcggcgcct
    15541 agcgttatga ttgctcaaag tttggggcgt tggggtaatt tctttaacca agaagcttat
    15601 ggtgcaacag tggataatct ggattatcta cctggcttta tccgtgacca gatgtatatt
    15661 gaggggagct accgtcaacc gactttcctt tatgagtctc tatggaatct gcttggcttt
    15721 gccttgattc tgatttttag acggaaatgg aagagtctca gacgaggtca tatcacggcc
    15781 ttttacttga tttggtatgg tttcggtcgt atggtcatcg aaggtatgcg aacagatagt
    15841 ctcatgttct tcggccttcg agtgtcccaa tggctgtcag ttgtccttat cggtctcggt
    15901 ataatgatcg ttatttatca aaatcgaaag aaggcccctt actatattac agaggaggaa
    15961 aactaaatgt tagaagttgc atatattctt gttgccctag ctttaattgt ctttttggtc
    16021 tatctgatca ttactgtaca aaagcttggt cgtgtcatcg atgaaacaga aaagacgatt
    16081 aaaaccttga cttcagatgt ggatgtgacc ttgcatcaca ccaatgagtt gttggctaag
    16141 gtcaatgtct tggcagatga tatcaatgtc aaggtggcta cgattgatcc actcttcagt
    16201 gctgttgcag atttatctct atctgtttca gacctcaatg accatgcgcg tgtcttgagc
    16261 aagaaagctt catcagctgg ttcaaaaaca ctcaagactg gtgcaagtct gtcagctctt
    16321 cgtcttgcaa gtaaattttt caaaaaataa aaaaggagaa tccttatggg taaattatcc
    16381 tcaatccttt taggaacggt ttcaggtgca gctcttgcct tgtttttaac aagtgataag
    16441 ggcaaacaag tttgcagtca ggctcaagat tttctagatg atttgagaga agatccggag
    16501 tatgccaagg agcaagtctg tgaaaaactg acagaagtta aggagcaggc tacagatttt
    16561 gttctgaaaa caaaagaaca ggttgagtca ggtgaaatca ctgtggacag tatacttgct
    16621 caagctaaat cctatgcttt tcaagcgaca gaagcatcaa aaaatcaatt aaataatctc
    16681 aaggaacaat ggcaagaaaa agccgaagct cttgatgact cagaagagat tgtgattgat
    16741 ataacagaag aataaaccat caccatctcc ggacggacta tgtatctggg gatggtgatt
    16801 tttatctgga atctagtctt tgtggtataa taattactat gcagaaaaaa ccaacgtcag
    16861 cctatgtgca catcccattt tgtacccaga tttgttatta ttgtgatttt tcaaaggtct
    16921 tcatcaaaaa tcagccagtc gacagctatt tagagcatct gctggaagag tttcgttctt
    16981 atgatattga aaagttgtca accctttata tcggtggtgg aacaccgaca gccctgtcgg
    17041 ctccgcaact ggaggtttta ctgaatggct tgactaaaaa cttggacttg tctgtcttag
    17101 aagagttgac cattgaagcc aatccaggcg atttgaatgc ggataagata gctgttttga
    17161 aaaattcggc tgtcaatcgt gtttcgctag gtgtccagac ctttgatgat aagatgttga
    17221 aaaagattgg gcgcagtcat ttggagaagg atatttatga aaatatcgat cgcctgaaac
    17281 tggctggttt tgacaacatc tccattgatt tgatttatgc tctgcctggt cagaccatgg
    17341 agcaagtaaa ggaaaatgtg gctaaagcca ttggactgga tattccccac atgagtttgt
    17401 atagtttgat tttagaaaac catacggtct ttatgaaccg gatgcgacgt gggaaattgc
    17461 ctctgcctaa ggaggaacta gaagcggaga tgtttgagta catcattgca gagctggagc
    17521 gagcgggttt tgagcattat gagatttcta atttctccaa acccggcttt gaaagtcgtc
    17581 ataatctcat gtactgggac aatgctgaat actatggtat tggtgcaggg gcatctggtt
    17641 atgtcaatgg agtacgttat aaaaatcatg gtcccattcg tcattatctc agtgcggttg
    17701 aggaaggcaa tgcttgtatt acagaagatc acctgagtca aaaggagcaa atggaagaag
    17761 aaatgttctt gggactccgc aagaaatccg gggtttccat ggcgcgattt gaggaaaaat
    17821 ttggacagtc ttttgctgga ctttatggag aaattgtcag agatttggtt caacaaggcc
    17881 tcatgcagat tgagggtgac cacgttcgca tgacaaagag aggtctcttt ttgggagata
    17941 ctgtagcaga acgatttatt ttggagtagg atcatgggct taacttatca aatgaaaatg
    18001 aaaattcctt ttgatatggc tgatatgaac ggtcatatca aacttccaga tgtgattttg
    18061 ctgtcactgc aagtttcagg gatgcaatcg attgaactgg gagttagtga taaggccatt
    18121 ttggaagact ataatctggt ctggattatc gcagaatatg atattgaggt ggttcgtttg
    18181 cctcgttttg cggaagaaat taccatcgaa acggaagcct tgagctacaa tcgacttttt
    18241 tgctaccgtc gctttactat ttataatgaa gcggggcagg agctcatcca tatgatggcg
    18301 acctttgttc tcatggaccg cgacagtcga aaagtccatg ctgttgaacc tgagattgtg
    18361 gctccttacc agtctgattt tgataaaaaa cttatccgtg gaccgaagta tgaatccttg
    18421 gaagagccga tcagcaagga ttaccatgtt cgtttttacg acttggatat gaatggtcat
    18481 gtcaataaca gtaaatactt ggactggatt tttgaggtca tgggagcgga ttttttgacc
    18541 cactatattc ccaagaaaat caacctcaag tatgtcaagg aagttcgacc aggtggggtg
    18601 attacatcgg ctgttgaacg gactggactg gaaagcaagc atgaaattac aagtgatggg
    18661 gttatcaatg cccaagcaat cattacttgg caagaaataa aaaaggttta gggagaaata
    18721 gatgaaatat aaaggctatt taattgattt agacggaacc atttataagg ggaaagaccg
    18781 aatccctgct ggagagactt ttgttcatga attgcaaaag cgggacattc cctatctctt
    18841 tgtaaccaac aatacaaccc gcactccaga gagtgttaag gagatgttgg ctcagaattt
    18901 taatatcgat acgcctctat cgactgtcta cacagcgact ttggcaacca tcgactatat
    18961 gaatgatttg gggcttgaaa agactgtcta tgtcgtcgga gaagcaggac tcaaggaagc
    19021 catcaaggcg gctggttatg tggaagacaa ggaaaaccct gcctacgtgg tagttggtct
    19081 ggattggcaa gtcgactatg aaaaatttgc cacagcaact cttgctattc aaaagggtgc
    19141 ccattttatc ggaaccaatc ctgacctcaa catcccgacg gaacgtggtc ttttgccagg
    19201 tgctggctca ctgattacgc tgcttgaagt agcgacacga gtgaagccgg tttatatcgg
    19261 aaaaccaaat gccatcatta tggacaaggc ggttgagcac ttaggtttgg aacgtgaaga
    19321 gttaatcatg gttggggaca attatttgac tgatatccgg gctgggattg acaatggcat
    19381 tccaacgctc ttggtgacga caggttttac taaggcagaa gaagtagctg gcctgccaat
    19441 cgcaccgaca catgtggttt ctagccttgc ggagtgggat tttgatgaaa actaaattga
    19501 ccttttgggg ctctatgctc tttctcctct ccctctcaat ccttctgacc atttatctgg
    19561 cttggatttt ctatcctatg gagattcagt ggctaaactt aacgaatcga gtctatctaa
    19621 aaccagaaac cattcaatac aattttcata tcttgatgaa ttatctgacc aatcctttta
    19681 gtcaggtctt acagatgcct gattttcgtt cgtcagcagc tggtctgcac catttcgcag
    19741 tggtcaagaa tctctttcat ttggttcagc tagtagctct agtgacactg ccaagtttct
    19801 atgtctttgt caataggatt gtgaaaaagg actttttgtc tctttatcga aaaagtctcc
    19861 tgactctagt agtcttacct gtgatgattg gacttggggg agttttgatt ggttttgacc
    19921 aattctttac tcttttccat caaattctct ttgtgggaga tgatacctgg ctttttgatc
    19981 cagccaagga tcctgttatt atgattttgc cagagacctt ctttcttcat gccttcctcc
    20041 tcttttttgc cctctatgaa agcttctttg ggtatctgtg tctgaaaagt cgtaggaagt
    20101 gaaatgaaag atgtttttaa tttgcatata taaaaatata tatatcgttt aaaaccatcg
    20161 ttaagagtga attaaccaaa tccaattgtg tcaatcgttc gcaaacagcc tatttttctt
    20221 gaaaaaatag gctttttttc taaaaatccc tagtcaagcg ctttattttt ttgtataata
    20281 gaagtagcaa agtatagata agaagagaaa agcatgatta cactatttct atcaccgagc
    20341 tgtacatcat gtcgtaaggc taaggcctgg ttagaaaaac ataaggttcc ctttgtggaa
    20401 cacaatatta tgaccagtcc tttaacaaga aaagaattgc aacacatcct ttccttgacc
    20461 gaaaatggta ctgatgacat catttcaact cgttcaaaaa tttttcaaaa attgaatatt
    20521 gatgtagaga gtatttcggt atcggaattg cttcatttga ttgagcagta tcctagtctt
    20581 ttgcgtcgtc caattattat tgatgccaag cgtatgcaaa tcggttttaa tgaagatgag
    20641 attcgtgctt ttctccctcg tagttatcgt aagcaagaac taaaagaagc aagaatgaga
    20701 gctggtatta gttaatgaac aaacagtata gttacccact agatttgtcg tggagcactg
    20761 aagaacttgc ttcagtgctt tcttttttta atgatgttga agctgcctat gaaggcaaag
    20821 tagaggctaa aaagttactg gactcctata agggattcaa agcggtcgtg ccaagcaaga
    20881 gcgaagagaa acgtttggga cgagaatttg aaacggttag tggctattca ctttaccgag
    20941 cagttcaggc tgccaaagaa aaaggggaag gaaagatttc tcttggaaag taaatttgaa
    21001 tttgctaaag agcttgttaa gaaagcaggc cagtacattc ttgaccatat gcaggaagac
    21061 ttgcgtgttg aaaccaagtc ctctccaaca gatttggtga ccagactgga caaagaagtt
    21121 caggaactct tggttggtga gattttgtcc cgttatcctg aggataagat ttgtgctgaa
    21181 gaaggttgtc tgcgagcctc ggttcaagag ggcaaggttt gggtcattga tcccattgat
    21241 ggtaccaata attttgtagc ccagcaggaa gattttgctg ttatgatggc ttattttgaa
    21301 aatggtcagg gacagtttgg tctgatttat gatgtggtca aaggggattg ttaccacggt
    21361 ggtggggaat ttccagtttg tctaaatgat aggcccctag ctccttttaa aactaaacca
    21421 cttggagatt ttctcattgc agggaatagt ggtatgctgg aaaccaatga atgggggctg
    21481 gctgatttga gccgagcggt tcttggtgtt cgtgtctatg gaagtgcggc cattagtttt
    21541 gccaagattt tgtcagggcg tttgttgacc tatctcactt atctgcaacc atgggattat
    21601 gccgcagcta gtattttagg ggaaagtctg ggctatcggg ttgtgaccct ttttggtgaa
    21661 gctcctgatt ttcaaaccag acagcctgtc atgatggtgc ctcttgagat gcaggaggaa
    21721 attcagtcct atatttacga aaggaaaaga acttaaatgc aatttccaga aggatttgtt
    21781 gaaaaatata aagaaatact aggagatgag gcaagagatt ttcttgcctc ttttgaggag
    21841 gaagcggttt cggcctttcg ggtcaatccc ttaaaagaag agcaactttc cttttctgat
    21901 gccattactc aaaccccttg gggccactat gggaaggttt cagggaaatc gcctgagcat
    21961 gctacaggtt tagtttattc gcaagaacct gctgctcaaa tggtggctca agtagcccaa
    22021 cccagtcctg gtatgaaggt cttggacttg gctgctgcac cggggggcaa atcaactcaa
    22081 ctggcagcct atctagcagg ggaggggcta cttgtttcca atgaaatttc aagcaaacgg
    22141 gctaagattt tggttgaaaa catggagcgt tttggagcga caaatgtcgt ggtgaccaat
    22201 gaatctgccg accgcttggt caaggtcttt aaaggctatt ttgacttaat cgttcttgat
    22261 gccccttgct ctggtgaagg aatgtttcgt aagcaacctg atgctatgga ctattggagc
    22321 ttagattatc cgagtcaatg tgctagcttg caaagagaaa ttctggagga tgcagtgacc
    22381 atgttagctg aaggtggtcg tctggtttat tcgacctgta cctgggcacc cgaggaaaac
    22441 gaagagattg tcaattggtt gctggaagag tatgattttg acttgttgcc agtagagcat
    22501 atcaatggaa tggtagctgg tattgacctg ccagaaacgg ctcggatgta ccctcatcag
    22561 tttaagggag agggtcagtt tgttgcccat ctacagttta agggtaacaa tccagctcct
    22621 aaatttaagg caagtaagag taacctcagc cgtgaacaag ttgccttgtg gcaggaattt
    22681 gcccaaaacc atttgaaggt caatctaccg ggtatcttgc agatttttgg agaccagctt
    22741 tatctcttgc cagaactttt gccagattta gggaagctca agattgctcg caatggactg
    22801 catctgggta cttttaagaa gaaacgcttt gagcccagtt tcgctcttgg tttagccttg
    22861 aaaccgagtc aggtcgaaca gtcggttgaa attggccaag aagcgtttgt caagtatgcg
    22921 gctggagaaa ccgttcagct ggcagaaagt ctgccaaatg gttggtacca agttttggtt
    22981 aaaggcaatg gcttgggctt tgcaaaggtt actggaaatg ttttgaaaaa ttattttcca
    23041 aaaggcctca gattcaaatg aaaatgctag tcaaatatct tattctatgt tatagtgaaa
    23101 gtatggattt ttttagtagg atgattcttg atatcttgat tgccatcaca tgtagtttta
    23161 ctactcgatg aaaatcaaag agcaaactag gaagctagcc atagatagct caaaacactg
    23221 ctttgaagag attttcaaag agtacaagaa gtttagttat tagcgttctt accgcttgta
    23281 aactagattt ctcataaaat agaatctttt ccttttagtt gtaaactagt ctgggagagt
    23341 agagaggttt gagatacctt tctagctttt ggattatcat ctaagaagag taatttccct
    23401 tgcattaaaa aggggaaaaa gagacacgaa atgactataa tgggtgacaa tgggggaagg
    23461 gatagacaag agattttatc cacatatgaa aaaaggaggt taggaaagag taatatagcc
    23521 tatattatat aaataatcaa ttgcgcagaa atttggtaag aattcatgcg tcaactcata
    23581 aagaactact taaaaaattc acagtattca taattatttt cgaggagaaa aacagtgaaa
    23641 aaaagaaaaa agcttgctct gtctcttatc gctttttggc tgacggcttg tttagtaggc
    23701 tgtgctagct ggattgatcg tggagaatcc ataacggctg ttggctcaac tgccttgcaa
    23761 cccttggttg aagtagcggc agatgaattt ggcacgatcc atgttggaaa aacggtcaat
    23821 gtccaagggg gaggttctgg tacaggcttg tcccaggttc agtctggggc agttgatata
    23881 ggaaactcag atgtatttgc tgaggaaaaa gacggaattg atgcttctgc tcttgttgac
    23941 cacaaggtcg cggtagctgg cttggctctg attgtcaata aggaggttga tgttgataac
    24001 ctaacgacag agcaacttcg tcaaatcttc ataggtgagg taaccaattg gaaagaggtt
    24061 ggtggtaagg acttacccat ctctgttatc aatcgggcag ccggctctgg ctctcgtgct
    24121 acctttgata ctgtcattat ggaaggtcag tctgccatgc aaagtcagga gcaggattca
    24181 aatggagcgg taaaatcaat cgtatcaaaa agtccaggag ctatctctta tttatctctt
    24241 acctatatag atgattcggt caaaagcatg aagttgaatg gctatgactt aagtccagaa
    24301 aatataagta gcaataattg gcccttgtgg tcttatgagc atatgtatac attggggcag
    24361 cccaatgagt tggctgcaga atttctcaat tttgttctct cggatgagac ccaagaaggg
    24421 attgtcaaag gattgaagta tattccgatt aaggaaatga aggttgaaaa agatgctgcc
    24481 ggaactgtga cagtgttgga agggagacaa taatgaatca agaagaatta gctaagaaaa
    24541 tgttgcttcc atcaaagaat tctcgtctgg agaaattagg aaaaggtttg acctttgcct
    24601 gtctttcttt gatagtcatc cttgtggcca tgattttggt tttcgtagcg caaaaaggct
    24661 tgtcgacctt ctttgtcaat ggtgtgaata tctttgactt tcttttggga ggaacttgga
    24721 atccttctag taaagaattt ggtgcccttc ctatgatttt gggttccttt atcgttacca
    24781 ttctctcagc ccttatcgca acaccctttg ctattggtgc agcagttttt atgaccgaag
    24841 tatcaccaaa aggggcgaag attttgcaac cagctattga actcctggtt gggattcctt
    24901 cagtagtgta cggatttatt ggcttgcaag tcgtcgttcc ctttgttcgc agtgtctttg
    24961 gtgggactgg ttttgggatt ttgtcaggga tttccgtcct ctttgtcatg attttgccga
    25021 ccgtaacctt tatgacaacg gatagcttgc gtgcggttcc tcgttattat cgtgaggcta
    25081 gtttcgctat gggagccact cgctggcaga ctatctggcg tgtgatcttg aaggcggccc
    25141 gttctggtat tttcactgca gtggtctttg ggatggcgcg tgcctttggt gaggctctag
    25201 ctatccagat ggttgtcgga aactcagctg ttatcccaac ttccttgacc acaccagctg
    25261 caactttaac ttctatatta actatgggaa ttgggaacac tgtcatggga actgtaaata
    25321 ataatgttct ctggtcactg gccttggtac tgctcttgat gagcttagtt tttaacagtg
    25381 tgattaaatt gattacgaaa gaaagaggaa agaaaaatta tgcgcgctaa gaaattagat
    25441 aaacttgcaa cagctgtcct ctatacgatt gctagcatca ttgtgacaat cttggcttcc
    25501 ttgattctct atatcttggt tcggggcttg ccccatatct cttggtcttt cttgactgga
    25561 aggtcttctg cttttcaagc aggtggtggg attggcattc agctttacaa ttcctttttc
    25621 ctattggtca ttaccttgat tatttctgta cctctttcta tgggagctgg gatttacttg
    25681 gctgaatatg ctaaaaaagg tcctgttacc aactttgtgc gaacttgtat tgaaatcttg
    25741 tcctctttac catcagtggt ggtgggtctc tttggttact tgatctttgt agtccagttt
    25801 gagtatggat tttcaatcat ttcaggtgct ttggccttga cagtctttaa cttgcctcag
    25861 atgacgcgta atgtagaaga tagtttgaaa cacgttcacc atacccaacg tgaggctggt
    25921 ctggctcttg ggatttctcg ctgggagaca gtggttcatg ttgttattcc agaagcgctt
    25981 ccaggtattg taacgggtgt cgtcttggca tctggtcgta tctttggcga agctgcagct
    26041 ctgatctata cagcagggca atcggcgcca gctcttgact ggtctaactg gaatatcctc
    26101 agtgtgacta gccccatctc tatcttccgt caagcagaaa ccttggctgt ccatatctgg
    26161 aaagtcaata gtgaaggcac tattccagat ggaaccattg tatcagcagg ttctgccgct
    26221 gtgctcctga tctttatcct gatttttaac tttggagctc gtaagttcgg aagctatcta
    26281 cacaagaaat taaccgctgc ctaaaggaga agccatgtca acatataact gggatgagaa
    26341 gcatatcctt acctttcctg aagaaaaagt agccctttct actaaggatg tccatgttta
    26401 ttatggtaaa aatgaatcca ttaaggggat tgatatgcaa tttgaaagaa ataaaattac
    26461 agctttgatt ggtccgtcgg gatcggggaa atctacctac ttacgcagtc tcaatcgcat
    26521 gaatgatacc attgatattg ctaaagtaac tgggcagatt ctctatcgtg gaattgatgt
    26581 caaccgtcca gaaatcaacg tttatgaaat gcgtaaacac attggaatgg tttttcaacg
    26641 ccccaatcca tttgctaagt caatttaccg taatattacc tttgcgcatg aacgtgctgg
    26701 agttaaggat aagcaagtcc tagatgaaat cgtagaaacc tcccttcgtc aggctgccct
    26761 ctgggatcag gttaaagacg atctccacaa gtcagccttg accttatcag gtggtcagca
    26821 acaacgtctc tgtatcgctc gtgccatctc tgttaagcca gatatcctct taatggatga
    26881 gccagcctca gccttggatc cgattgcgac catgcaacta gaagagacca tgtttgagct
    26941 caagaaaaac tttaccatca tcattgtaac gcataatatg cagcaggctg ctcgtgcaag
    27001 tgactataca ggcttctttt acttgggtga tttgattgag tatgacaaga ctgcaactat
    27061 tttccaaaat gccaagctac agtccaccaa tgactatgta tctggtcact ttggttagaa
    27121 aggaaaccgt atgacagatg cgattttaca ggtatcagac ctgtccgttt attataataa
    27181 aaagaaggct ttgaatagtg tttccctatc tttccaacct aaggaaatta cagccttgat
    27241 tggtccatct ggatcaggga agtcaaccct cctcaagtct ctcaaccgca tgggagatct
    27301 caatccagag gtgaccacaa ctggatccgt ggtgtacaat ggtcacaaca tctacagtcc
    27361 gcgtacagat acggttgaat tacgtaagga aatcggaatg gttttccaac aacctaatcc
    27421 tttccctatg actatctatg agaatgttgt ctacgggctt cgtatcaatg gaattaagga
    27481 taagcaggtt ctggatgaag ccgtagaaaa agccttgcaa ggtgcctcta tctgggatga
    27541 ggtcaaggat cgtctatatg attcagctat tggattgtca ggtggtcaac agcagcgtgt
    27601 ctgcgtggcc cgtgtcttgg caactagtcc taaaatcatc ctcttggatg agccaacttc
    27661 ggctttggat ccgatttcag ctggtaagat tgaggaaacc ttgtatggtc taaaagacaa
    27721 gtacaccatg cttctggtaa cccgttccat gcagcaagct tcacgtatct ctgataagac
    27781 aggatttttc ctagatggag atttgattga atttaatgat accaagcaga tgttccttga
    27841 tccccaacac aaggaaacgg aagactatat tacaggaaaa tttggataag gagatgaaag
    27901 atgttacgat ctcaatttga agaagattta gagaaattac ataaccagtt ctacgctatg
    27961 ggacaagaag tgctctcaca aatcaatcgt acggtacgtg cttttgtcac gcatgaccgt
    28021 gacctggcaa aagaggtcat agaagatgat gcagaagtaa atgaatacga agtgaaactg
    28081 gaaaagaaat catttgaaat gatcgcactc caacaaccag tctctcaaga tttgcgtaca
    28141 gtcttgactg tccttaaggc tgtatcagat gtggagcgta tgggggatca cgctgtagcc
    28201 attgcccagg caaccatccg tatgaagggg gaagagcgca tcccagctgt agaggaagaa
    28261 attaaaaaaa tgggacgtga agttaaaagc gttgttgaag cagcacttga tctttatctt
    28321 aatggttctg ttgacgacgc ataccgggtg gcctccatgg atgagcaaat taaccactat
    28381 tttgaaacta tccgtgacct tgcgactgaa gagattaaga aaaatccaga agccattgtt
    28441 acgggtcgtg attatttcca agttatttcc tacttggagc gtatcggtga ctatgctaaa
    28501 aatatctgtg aatgggttgt ctactttgaa acaggtaaga ttgtcgaact ataaaatagt
    28561 ttaattctgt ataaaaagga gcttgaaatc aactgatggc tccttttttt gaacgaaaaa
    28621 atatttttga gataaaaatt taaaaaacac ttgacaagta acttggatat cgttataatt
    28681 atacaaaatt aacagagagg ttgtttattt atgaaatcaa aaaaatggat atttgtttta
    28741 tgtaattttc ttgcaagttt cttcttagta gcttgccagt caggttctaa tggttctcag
    28801 tcagctgttg aggccattaa gcaaaagggg aaattagttg tggcaaccag tcctgactat
    28861 gcaccctttg aatttcaatc attggttgac ggaaagaatc aggtagtcgg tgcagacatc
    28921 gacatggctc aggctatcgc tgatgaactt ggggttaagt tggaaatctc aagcatgagt
    28981 tttgacaatg ttttgaccag tcttcaaact ggtaaggctg acctagcagt tgcaggaatt
    29041 agtgctactg acgagagaaa agaagtcttt gatttttcaa tcccatacta tgaaaacaag
    29101 attagtttct tggttcgtaa ggctgatgtg gaaaaataca aggatttaac tagcctagaa
    29161 agtgctaata ttgcagccca aaaagggact gttccagaat caatggtcaa ggaacaattg
    29221 ccaaaagctc aattaacttc cctaactaat atgggtgaag cagtcaatga attgcaggct
    29281 ggaaaagtag atgctgttca tatggatgag cctgttgcac ttagttatgc tgctaaaaac
    29341 gctggcttag ctgtcgcaac tgtcagcttg aagatgaagg acggcgacgc caatgccgtt
    29401 gctcttagaa aaaatagtga tgatttgaaa gaagtggtag acaaggtcat ccaaaaactt
    29461 aaggatgaag gaacttacca aagctatctt gaaaaagcag caagtctaac tgaagttgaa
    29521 gaataagaaa aagcagagtt ggatgtcatt ccaattctgc ttttaaatag tttaaaacat
    29581 tttccagatt gtctagggac accttggcaa attgataagg acaggtgctt aaataggcct
    29641 cttcaaagaa gtccaagccc agttgactgt gtttgagact ggcgatttta ggatactgtc
    29701 tcaggtctag caataaacca tcgtgtaggg gataatgagg aaggggacaa ggtgttttag
    29761 ttatcctttc ctcgatttgt ttttggtaag attcatgatt ggtcaagcga gccaaacgat
    29821 ttttttcaaa caattgactg tcaatataga gtgacagggc cttttgcata atgaggttgc
    29881 tgtcgtagtc taggatattt ttgtaggcca caaatgcttc tttgatagca tttggaagaa
    29941 tgagtgctgt aatacgaagg gcaggaaaaa ggctggtcga gaaggacttg atataaatga
    30001 cacgctcctc tgtatcaaga tagtggaagg tttggccctt cttggagtcc aaatcaccca
    30061 gataatcgtc ctctacgata tagacatcat acttggcagc taagttaaga atagatcgtt
    30121 tgtcctgctc agaataggaa tgtcccagag gatagtgaaa tcggggaatg gtgtagaaaa
    30181 atttaatttt tcctgttttg aagtggcctt ccagctcctc caagtcaatc ccatcaatgc
    30241 ctcgttcaat cgtttgatag tccagcccct gtgcaatcaa gaggcgattc atccgatggt
    30301 aggttggctg ttccaccaag atttccttgg cttgtctagg aaaggatatt tgagagagga
    30361 taaacaaggc ttgttgggtt ccagaagtca gtactagttg gttagccttg cagtagagag
    30421 cttgctcaaa gaggagtttg tgaatggact gtcttaggtc ttctaatcct tcttgattgt
    30481 catagtagtt gaagaggtag ttttctcggc caatcaaggt ttcattgaca cagagtcgga
    30541 aatcgtcata ggcactggca tgttcgtcgg taacctcgat ttctaggtct tgatgttgcc
    30601 cttgttctaa tacatagtag ccactctgag gcttggcata gaggtattgt tcgtgccgta
    30661 attccagcag ggctcgttga atggtgtcct tgctgcagtg aaagtcaagg ctcagttgac
    30721 ggatagaagg caggcgacta cccgtcggaa atcgttcaga ctcgatacca tttttcagat
    30781 aggaaacgac ctctttgtac ttgctttgtt tcttcattcc agacctccct tgattttgtt
    30841 acattgtacc cttttttttc cttcttggca atgtctagag cgtttctctc gttcacatct
    30901 aggggcaaat gtggtatact taggagtaag atttatagaa taacagacaa gaaagtgaat
    30961 ggataagaac gtgcaggaac cagtgaaatt atttcaatac aatactcttg gagccttgat
    31021 ggctggcctt tatggtggta ctatgacagt aggagaattg ctagaacatg gtgaccttgg
    31081 tttgggaacc ttggattcca ttgatgggga attgattgtc ttggatggca aggcttatca
    31141 ggccaaaggg tcaggagacc agccagaaat tgtggaagtg tcaccagatg cccttattcc
    31201 ttacgctgca gtggtaccgc atcaggcaga ggtcattttc cgccagcgct ttgagatgac
    31261 agacaaggaa ttgaaagaac gaattgagtc ttattatgat ggggaaaatc ttttccgttc
    31321 tatcaagatt cggggggaat tttcacatat gcatgtgcgt atgattccta agtcaacacc
    31381 cgataccaag tttgctgatg tcgcaaccca tcaaccggaa tatagtcgtg acaatgttgc
    31441 ggggactatt gttggtttct ggacgcctga gattttccat ggggtcagtg tggcaggcta
    31501 ccatctgcac ttcatatcag atgatttgac cttcggtgga catgtcatgg attttgtcat
    31561 caaggaaggc attatcgagg tgggagcagt tgaccagttg gaccaacgtt tcccagtcca
    31621 agaccgtcaa tacttgtttg ctaagttcaa tgttgacgag atgaaaaaag atattgaaaa
    31681 ggcagaatag gagaagaaaa tgaccattca tatcattatt accatgttgc tgttgctagc
    31741 ttttctgata ggaagcattt ggtttgccaa aaagaaatac cagattaatc tagctgtctt
    31801 gggcttgggt gcagtcgctt tctttgtctc ttcgcagatt ttggaaaaac tggtgcatat
    31861 cttgattttg catcctcaaa aaagacggta gtattgccct cttgcaagat cacccgcttg
    31921 tctatattat ctatggccta gctatggcag cattttttga ggaaacggct cgtcttgttt
    31981 tcttcaaatg gttggagaaa aagagaagtt tggaaaaggc agacgccttg gcctatggac
    32041 tggggcatgg tggcttggag ttgatttttc taggccttac tagtttactc aatctttaca
    32101 ttgttctttc ggcagttcaa actcagaatc cacaggttat gcaattactg tctgaaaata
    32161 tgttaaaaac cattcagtca ctttcggtct ggcagattta tttgcttggt tttgagcgaa
    32221 tcttggcgct tggtttccaa ttacttttga cagtttgggt ttaccaagct gttcgccaga
    32281 agaaatggat ttatctccta gcagcctatg gcttgcatgc cttctttgat ctggcaccat
    32341 ctctttccca agtaggctgg ttgacaaatc cagtcttggt tgaagtgatt ctagcactgg
    32401 agctcgttct ggtcgcctat ggaaccaagg aaatcttttg taaaaaatca taaaaagggg
    32461 gaaacctctt tttcttatgc aaaatccaaa caaggtattt ttatggtcgt caaatgtctc
    32521 taaaaatggt ataatggaat gaattttgta aaaggaagag tgacatgtct gtaagagaaa
    32581 aaatgcttga aatcttagaa ggaattgata tccgttttca ggaacccttg catagctata
    32641 gttatacaaa agtaggtgga gaggctgatt atttggtctt tccacgaaat cgttttgagt
    32701 tggctcgcgt tgtgaaattt gccaaccaag aaaatatccc ttggatggtt cttggcaatg
    32761 caagcaatat catcgttcgt gatggtggga ttcgtggatt tgtcatcttg tgtgacaagc
    32821 tcaataacgt ttctgttgat ggctatacca ttgaagcaga agctggggct aacttgattg
    32881 aaacaactcg cattgccctc cgtcatagtt taactggctt tgagtttgct tgtggtattc
    32941 caggaagcgt tggcggtgct gtctttatga atgcgggtgc ctatggtggc gagattgctc
    33001 acatcttgca gtcttgtaag gtcttgacca aggatggaga aatcgaaacc ctgtctgcta
    33061 aagacttggc ttttggttac cgccattcag ctattcagga gtctggtgca gttgtcttgt
    33121 cagttaaatt tgccctagct ccaggaaccc atcaggttat caagcaggaa atggaccgct
    33181 tgacgcacct acgtgaactc aagcaacctt tggaataccc atcttgtggc tcggtcttta
    33241 agcgtccagt cgggcatttt gcaggtcagt taatttcaga agctggcttg aaaggctatc
    33301 gtatcggtgg cgtagaagtg tcagaaaagc atgcaggatt tatgatcaat gtcgcagatg
    33361 gaacggccaa agactacgag gacttgatcc aatcggttat cgaaaaagtc aaggaacact
    33421 caggtattac gcttgaaaga gaagtccgga tcttgggtga aagcctatcg gtagcgaaga
    33481 tgtatgcagg tggttttact ccctgcaaga ggtagtgggg acctgacaga gccccgatcg
    33541 gttaatctat gaaaaagaag gaatttatgc caattgaaaa aaccaattat cgaattcaaa
    33601 aacgtctcta aagtttttga agacagcaac accaaggttc tcaaagacat caactttgag
    33661 ttggaagaag ggaaattcta cacccttcta ggtgcatctg gttcggggaa atcaactatc
    33721 ctaaacatta ttgcaggttt actggatgcg acgacaggag atatcatgct agacggtgtt
    33781 cgtatcaatg atattccaac caacaagcgc gacgtacata ccgtcttcca atcctatgcc
    33841 ttgttcccac atatgaatgt gtttgaaaat gttgcctttc cacttcgctt gcgtaaaatt
    33901 gataagaaag aaatcgagca gcgtgtagcg gaagttctca agatggttca gttggaaggt
    33961 tatgaaaaac gttccatccg caaactttct ggaggacaac gtcagcgtgt ggccatcgcc
    34021 cgtgctatca tcaaccaacc ccgtgtggtc ttgttggacg agcctttatc agcgctggac
    34081 ttgaaattga gaacagacat gcagtacgaa ttgcgtgaat tacaacaacg attgggcatt
    34141 acctttgtct ttgtcactca cgatcaggaa gaagctcttg ccatgagtga ctggattttc
    34201 gttatgaatg atggcgagat tgtccagtct ggaacccctg tggacatcta cgatgagcca
    34261 atcaaccact ttgttgccac ctttatcggg gagtcaaaca tcttgccagg taccatgatt
    34321 gaggactact tggtcgaatt taacggcaaa cgctttgaag cggttgatgg tgggatgaag
    34381 ccaaatgaac ctgttgaggt cgttattcgt ccagaggact tgcgcattac ccttcctgaa
    34441 gaaggcaaac tccaagttaa ggtcgacacc cagctcttcc gtggagttca ttatgaaatt
    34501 atcgcctatg acgaacttgg aaatgaatgg atgatccact caacccgtaa ggccatcgtg
    34561 ggtgaggaaa tcggtctgga ctttgaatca gaagacatcc acatcatgcg tctcaatgaa
    34621 accgaagaag agttcgatgc tcgtatcgaa gaatacgtgg aaatcgaaga gcaagaagca
    34681 ggtctgatca atgcgatcga ggaggaaaga gatgaagaaa acaagctcta aactctttgt
    34741 agtgccctac atgctttgga ttgccctctt tgtattggca cccttggtct tgattttcgg
    34801 acaatccttt ttcaacattg aaggccagtt tagtttagaa aattataaat cttactttgc
    34861 gtcacaaaac ttgacctacc tcaaaatgag tttcaactca gtgctttatg caggcattgt
    34921 gacctttgtg accttgctta tcagctatcc aacagccctc tttttgaccc gtctcaagca
    34981 ccgtcaactc tggctcatgc tgattatcct tcctacctgg atcaatttgc tccttaaagc
    35041 ctatgctttt atcgggattt ttggtcaaaa tggctctatt aaccaattct tggaatttat
    35101 cggaattggt tcacaacagt tgctttttac cgatttttcc tttatctttg tcgcaagcta
    35161 catcgagctc ccctttatga ttttgccgat tttcaatgtc ttagacgata tggataataa
    35221 tctcatcaat gctagttatg accttggtgc aactaagtgg gagaccttcc gtcatgtcat
    35281 cttccctcta tctatgaacg gtgtgcgaag tggggttcag tcggtcttta tcccaagttt
    35341 gagtctcttc atgctgaccc gtttgattgg tgggaaccgc gttatcacct tggggacggc
    35401 tattgagcag aattttctaa ccaatgacaa ctatggtatg ggttcaacca tcggtgtgat
    35461 tctcatcctg accatgttca tcaccatgtg ggtgactaag gaaaggagag aacgatgaaa
    35521 aaatttgcca acctttatct gggactggtc tttctggtcc tctacctgcc tatcttttac
    35581 ttgattggct atgcctttaa tgctggtgat gatatgaata gctttacagg ttttagctgg
    35641 actcactttg aaaccatgtt tggagatggg agactcatgc tgattttggc tcagacattt
    35701 ttcttggcct tcctatcagc tttgatagcg accattatcg ggacttttgg tgccatttac
    35761 atctaccagt ctcgtaagaa ataccaagaa gcctttctat cactcaataa tatcctcatg
    35821 gttgcgcctg acgttatgat tggtgctagc ttcttgattc tctttaccca actcaagttt
    35881 tcacttggct ttttgaccgt tctatctagt cacgtggcct tctccattcc tatcgtggtc
    35941 ttgatggtct tgcctcgact caaggaaatg aatggcgaca tgattcatgc ggcctatgac
    36001 ttgggagcta gtcaatttca gatgttcaag gaaatcatgc ttccttacct gactccgtct
    36061 atcattactg gttatttcat ggccttcacc tattcgttag atgactttgc cgtgaccttc
    36121 tttgtaacag gaaatggctt ttcaacccta tcagtcgaga tttactctcg tgctcgcaag
    36181 gggatttcct tagaaatcaa tgccctgtct gctctagtct ttctctttag tattatccta
    36241 gttgtaggtt attactttat ctctcgtgag aaggaggagc aagcatgaaa aaaatctatt
    36301 catttttagc aggaattgca gcgattatcc ttgtcttgtg gggaattgcg actcatttag
    36361 atagtaaaat caatagtcga gatagtcaaa aattggttat ctataactgg ggagactata
    36421 tcgatcctga actcttgact cagtttacag aagaaacagg aattcaagtt cagtacgaga
    36481 cttttgactc caacgaagcc atgtacacta agataaagca gggtggaacg acctacgata
    36541 ttgccattcc aagtgaatac atgattaaca agatgaagga cgaagacctc ttggttccgc
    36601 ttgattattc aaaaattgaa ggaatcgaaa atatcggacc agagtttctc aaccagtcct
    36661 ttgacccagg taataaattc tccatccctt acttctgggg aaccttagga attgtctaca
    36721 acgaaaccat ggtagatgaa gcgcctgagc attgggatga cctttggaag ccggagtata
    36781 agaattctat catgctcttt gatggggcgc gtgaggtgct gggactagga ctcaattccc
    36841 tcggctacag tctcaactcc aaggatctgc agcagttaga agagacagtg gataagctct
    36901 acaaactgac tccaaatatc aaggctatcg ttgcggacga gatgaagggc tatatgattc
    36961 agaataatgt tgcaatcggc gtgaccttct ctggtgaagc cagccaaatg ttagaaaaaa
    37021 atgaaaatct acgttatgtg gtaccgacag aggccagcaa tctttggttt gacaatatgg
    37081 tcattcccaa aacagttaaa aaccaaaact cagcctatgc ctttatcaac tttatgttga
    37141 aacctgaaaa tgctctccaa aatgcggagt atgtcggcta ttcaacacca aacctaccag
    37201 cgaaggaatt gctcccagag gaaacaaagg aagataaggc cttctatccc gatgttgaaa
    37261 ccatgaaaca cctagaagtt tatgagaaat ttgaccataa atggacaggg aaatatagcg
    37321 acctcttcct acagtttaaa atgtatcgga agtaggagat aaacgtaaga agacgaatca
    37381 gtcaagctgg ttcgttttta aggaatagaa gtcagttttt agagccctat ctttttctat
    37441 tctagttgtt tatttgttta tttgcttatt tgcttgccta gtagtatact aagcctatac
    37501 tcttcaaacc acgtcagcgt tgccttgccg tactcaagta cagcttgagg ctagcttcct
    37561 agtttgcttt ttgattttta ttgagtatta accttacaga aagcggcaac aaataatgaa
    37621 aatgtctact tttttcaaaa aaagtttctg gccaaccttt atgattgtta accaaactgc
    37681 tatactattc catttaaagg atggcttgga tcgacaatac ctaacaactg agtccatata
    37741 ttgggtgata ggcaccttta tatttggaaa tattctagta gctgtgttta gtaatatgaa
    37801 aatttgggat aaaaagaaaa acggcagtaa gaaaaaatat atcctgaaaa agtaatcaga
    37861 gatgtaggga attggtctaa ttcaacggag atcatttcca gttgacgcaa gcttaaaaaa
    37921 acgttataat aagaaagttg agaattgatt ttcacttgtc ttagtccaga gaaatggcgg
    37981 tgctgcgagc catctaagct aggaagtcat gctgctcaat catacaattg cataagaaca
    38041 agagaatgac aagttcattg aatgaaggtg gtaccgcggt ttttcgccct tcgtgatatg
    38101 agcttgtctt ttgatttttg gaggtgttga tgaaaacatt tcttgtcaaa caaaagtttc
    38161 gtcttggagg cgaacgcttc gctatcaagg atgacagggg agaaattgcc tatcaggtgg
    38221 agggatcatt ttttaagatt cctaaaacct ttaccatcta tgatgcggct ggtgaacaag
    38281 tcagtgagat tagtaaagaa atcttgacct tgcttcctcg ttttgagatt cagcttcggg
    38341 atggctcgag ttttgtcatt cgtaagaagt tgaccttctg gcgagataag tatgagtttg
    38401 ataatctagg tcttcgtatc gagggcaata tctgggattt gaatttcaaa ttgctggatg
    38461 atcgcgatca gttgattgcg gaaattaaga aggaactctt ccatctgacc tctacctata
    38521 ccgtaacggt tcttgaagac gcttatgcag acctagtcat ttccctctgt gtcgcgattg
    38581 actatgtgga aatgctggaa agccaatcac attaaacaag taaataagga gacaatatga
    38641 aacaactatc tagtgcacaa gtacgccaaa tgtggcttga tttctgggcg accaaaggtc
    38701 actcagtaga accatcagta agtttggttc ctgtaaatga cccaactctt ttgtggatca
    38761 actctggggt agcaaccctt aagaaatact ttgacgggac cattatccct gaaaatccac
    38821 gtattaccaa tgcccaaaag gctatccgta ccaacgacat cgaaaacgta gggaagactg
    38881 cgcgtcacca taccatgttt gaaatgttgg ggaacttctc tatcggggat tacttccgtg
    38941 acgaagctat cacttgggct tatgagcttt tgacaagccc tgaatggttt gatttccctg
    39001 ctgaaaaact ttacatgacc tactatccag acgataaaga ttcttacaac cgctggattg
    39061 aagtgggagt ggatccaagt cacttgattc caattgagga caacttctgg gaaatcggtg
    39121 cgggaccttc tggaccagat acagaaatct tctttgaccg tggggaagcc tttgacccag
    39181 aaaatatcgg tcttcgcctg cttgcagaag atattgaaaa cgaccgttat attgaaatct
    39241 ggaacatcgt tttgtcacaa tttaacgcag accctgctgt tcctcgtagc gaatacaagg
    39301 aattgccaca taagaacatt gatacgggcg ctggtttgga gcgtttggtg gctgttatcc
    39361 aaggggctaa gaccaacttt gaaacggacc tctttatgcc gattatccgt gaagtcgaga
    39421 aattgtctgg taaggtttat gaccaagatg gcgacaacat gagcttcaag gttatcgcag
    39481 accacattcg ttctctttca tttgctatcg gtgatggtgc ccttccagga aatgaaggtc
    39541 gtggttatgt tcttcgtcgt cttctccgtc gtgcttctat gcatggtcaa aaattgggta
    39601 tcaacgagcc tttcctttac aaacttgttc caactgttgg aaacatcatg gaaagctact
    39661 acccagaagt gcttgagaaa cgtgacttta ttgagaaaat cgttaagagc gaagaagaat
    39721 catttgcccg tacccttcac tcaggtcaac actttgccca aggcattgtg gcagacttga
    39781 aagaaaaagg tcaatctgtc attgctggtc aagatgtctt taaactctat gatacatacg
    39841 gattcccagt tgaattgact gaagaaattg ctgaagaagc tggtatgact gtagaccgtg
    39901 aaggttttga agcagccatg aaagaacagc aagaacgcgc gcgtgcgtca gctgtcaagg
    39961 gtggctcaat gggtatgcaa aatgaaactc ttcaaaacat cactgtagaa agtgtcttca
    40021 actacaatgc tagccaattg tcttctaaat tggtagctat cgttgctgac aatgcagaag
    40081 taggagctgt ttcagaagga actgcctctc ttatctttgc ggaaacgtca ttttatgctg
    40141 aaatgggtgg acaggtagct gactacggac aaatcttgga tgagtcaggt aaggttgtgg
    40201 ctactgtgac caatgttcag aaagccccaa atggtcaagc ccttcataca gttgaagtcc
    40261 ttgcaccgct tgccttgaac caagaatata ccttggcaat tgatagcaat cgccgtcacc
    40321 gtgtcatgaa aaaccacact gcgactcatt tgcttcacgc tgcccttcac aatatccttg
    40381 gaaaccacgc aacacaggca ggatctctta acgaagttga attccttcgc tttgacttta
    40441 cccacttcca agcagtaact gctgaggaac ttcgtgcgat tgaacagcaa gttaacgaga
    40501 aaatttggga agcacttgaa gtgaagacag ttgaaacgga tattgacact gctaaagaaa
    40561 tgggagctat ggccctcttt ggtgagaaat acggcaagga agttcgtgtc gtgactatcg
    40621 gtgactactc tattgaactt tgtggtggta ctcatgttgg caacacttct gagattggtc
    40681 tcttcaaaat tgtcaaagaa gaaggaatcg gttcaggaac tcgccgtatc ttggcagtga
    40741 ctggtaagga agcctttgaa gcctatcgtg aacaagagga tgctcttaaa gctgtcgcag
    40801 caaccttgaa agcacctcaa gtcaaggaag tacctcacaa ggtagaagga cttcaagaac
    40861 aacttcgtca acttcaaaaa gaaaatgctg agttgaaaga aaaagccgca gctgcagccg
    40921 caggcgatat cttcaaagat gctaaggaag tcaacggtca tcgttacatt gctagtcaat
    40981 tgtctgtatc cgatgccggt gcccttcgta cttttgcaga taactggaaa caaaaagact
    41041 actctgatct tcttgtccta gttgccgcta tcggtgacaa agtcaatgtc cttgtagcaa
    41101 gcaagacaaa agaccttcat gcaggaaacc ttgtcaaaga attagcacca atcatcgatg
    41161 gacgtggtgg tggtaaacca gacatggcca tggcaggagg aagaaaccaa gctaagatcc
    41221 aagaattgtt ggatgcagta gcaggtaaat tgtaatcaag taaagatcta tccatttggg
    41281 taggtctttt tgtgaataca aaaaagccaa atccgcttgg acctagcttg gttattatga
    41341 gctattagat ggtattgact gcccagacac ttacggatct agctgagaca gggaattgtc
    41401 cataaccttc ctcatcaatt gtaacttgac cttggtggtt accaagtaaa tctacaaagg
    41461 tttgattagt ccattcttga ccgacaaaca ttgacttgct gttttcttgg tcatttgaga
    41521 taaggactgc gattggggat tgattttcag cacctgaacg tacccaaccg atacagttag
    41581 catggtcaaa gtagtcattt tgttctccat aggccaagtc ttttcggatg gctaggaggc
    41641 ggtcaaggat ttctttgaaa tcttcttgag catactggcc tgaaatccca tagtagtctc
    41701 cgtaaaagac acatggaagg ccgtcttggc gtaacaaaat gagggcatag gctgctggct
    41761 tgaaccattc ttcaacggta gactcaaggg cttgtcctcg ttgggtatcg tggttgtcga
    41821 taaaagtcac agccttgtca ggcttgagtt caaccaggct atctgtgaaa atgccacgaa
    41881 ggtcatagtt tgcgccagct tgactggctt caaagagatt ctggtggaga cgaacatcga
    41941 caaggtcaaa gtgttcttcc gttttttcga gatagtccag attggcttcc ttgtctgggt
    42001 tccaaaattc accaaaaaca tagaaatcgt caccgtattt ttccttcata tcgcggatga
    42061 aattgcgcat aaagaaagag tcaatatgct taacggcatc caaacggaaa ccagctacac
    42121 cagtcgtttc catgaaccaa tcagcccagt catagatgtt ttggatgact tcaggatgtt
    42181 taaagtctag gtcggcatac atgaggtagt cgtagtttcc gttttcgtta tcgaccaatt
    42241 cctcgttagc ccagcccttg ttgtctcctt ggattaggta aatcccggat ttacggcgtt
    42301 tggcatcata gtctgtacct gtgaagtggt accagtgcca gtggaagtca ttgtaggtat
    42361 cttggcgacc atcgaaggta aaactagtcc agccattgat ggtgaagggt tctccaagtt
    42421 caactgtacg gtctacagga tccacttcaa taacctgaaa ggcttccctg tgatcagcag
    42481 cagccttgtg gttgagaact acatcggcca taggttgaat tccctgcgct ttaagggctt
    42541 gaatggcttg aagatagtct tctttgaaac catacttggt gcggacagtc cctttttggt
    42601 tgaactctcc taagtcaaat aagtcataga ccccatagcc gacatctttt tcgttggttg
    42661 ccttgaaggc tggtggcatc cagacgtgac tgatccccag atgagctagg tgtggagcat
    42721 tttcagccag acgcgtccag tgttgaccgt cgtggggcag ataccattca aagtattgca
    42781 tgagtgtttg attttgcatg atgtttcctc ttacttgtca atcttgttct ttattctatc
    42841 ataaagtatc tctcggagca aacgtttgcg taagatagaa ggaaactatt ttaactactt
    42901 aaaataaagt attgattttt ttgtatcaaa gtgctagtat agcgatatat aatacagata
    42961 aagataggag tcatcccatg attgaatttc aaaatgttag taagttgtat ggtgataaag
    43021 aggccttgag taatctcaat ttgcagattg aaaatggaga gattatgggc ttgattggtc
    43081 ataatggggc tggaaaatcg accaccataa aatccctagt cagtatcatt tcacccagca
    43141 gtggtcgtat tttggtagat ggtcaggagt tatcggaaaa tcgcttggcg atcaaacgaa
    43201 agattggcta cgtagcagac tcgcctgact tatttttacg tttaacggcc aatgaatttt
    43261 gggaattgat cgcctcatcc tatgatctga ctagctctga cttggagact agtctagcta
    43321 ggctattgaa cgtttttgat tttgctgaaa atcgttatca ggttattgaa accctttctc
    43381 atggaatgcg tcagaaagtt tttgtcatcg gggcactctt gtctgatcct gatatttggg
    43441 tcttggacga acccttgact ggtttggatc cccaggctgc ctttgatttg aaacagatga
    43501 tgaaggaaca tgcacaaaaa gggaagacgg tcttgttttc aactcatgtc ctagaggtag
    43561 ccgagcaagt ctgtaatcgg attgccattt tgaaaaaggg gcatttgatc tattgtggta
    43621 gtgtagagaa cttgaggaaa gaccacccag accagtcttt ggaaagtatc taccttagtc
    43681 ttgctggtag aaaagaggag gttgcggatg cgtctcaagg tcattaaaaa attagttgat
    43741 atcaatatcc tctattcatc tcaagaagct aatctggcta atctacgaaa gaagcaggct
    43801 aagaatcctg ggaaaaaagt aaatgtttcc gctagagtcc taagttctta cattttttct
    43861 agtctcttga tgcttttcat gtttataaat atagcctttc gttttccttt tgaggaaatg
    43921 ccaagttttt ttagtacgat ggttgctatt ttactggtgc tggccttttc aacttctttc
    43981 actgcatttt acaatgtctt ttatgagagt aaggacctgg cctcctatag gccctatgcc
    44041 tttaaagaat cagagattat aatggccaaa ggtctgtctg tcctcttgcc agctctagct
    44101 ggaattgtac caatcctagc ttattttctg gtcctctaca ttaggctagc accttctctg
    44161 tggttgggtt tgcctttgat gctactgtcc ttgaccttat tatttgtctc tgttacttta
    44221 gtgatggtag tggcagtaca tttcttggct cagactaggg tcttcagaaa gtatcggtct
    44281 attttttcga atgtgatgat tgggatagga gttctcatac ctttaatatt tatcttcttt
    44341 cttcagtcga cttttggaag tattgttgac aaagttagag acattccatt tctcctttat
    44401 cctcttcata tcttttacaa aatagcagtg gagccttttt cgacagaagc cttagtgggt
    44461 ctgctcgctt ggataggact aactctcttc ctgctttatc tgaccaaaaa gaaggtcctt
    44521 cctcgttttt atgacgtgat cctgcttaat agtgaggata aggtcaaaaa agaacgtcgc
    44581 agcaaggaga gaatttcaac cactaaaaag ggattttttc gcatggtttt acgctaccac
    44641 ctcaccctct tgggacaggg gactggcgtg gttacagtgc tttttacaag tgctttcttt
    44701 ccttatctca tgatgatcgg tctgatttcc aaaatccgag attctcagat agttccagac
    44761 attcatcctc catactggtt acccttgttt tttatagctc tctttatagc agttgtcaat
    44821 aacaatatca ccagcctgca ttcaattgcc ttgtccttgg agagggaaaa tgttgatttt
    44881 cttaagagtt taccctttga ctttgctcgt tatgtgaaag tgaaattttg gattatatat
    44941 gctgtccagt cctttttacc agttctgact ttgcttggtc tttctctata tctaggcttg
    45001 cccatcattt cgatgattta ccttattgtg gcatggatcc ttgccagtgt catcctttct
    45061 tgccaccatt actttaagga cgttaaaaat ctgtcaacca attggagtag cattacggac
    45121 ctggtgaatc gttcaaatgg catagtcgcc atagttttat tgtttattta tagtgcaatc
    45181 ctgatggccc ttgtaattgg gagcatattc ttggttcagt ctctctccac tatccttgcc
    45241 atcagcttgg gagtaggagc tcttatcctc ctgcttgctc ttgctatttt tggctatcat
    45301 tattacctgt cacgcatatt ggcagaaata gaaaaaagat gagctggttg gtcgcttgct
    45361 tgataaattc aattcgacaa acgcttttat agtttgttag aatgtagttg taaatgatta
    45421 agattggtaa tcaaaaatat agggaggaat gttttgaata agaaatataa catagttcta
    45481 tttttgttgt ttatagttta tttatttgga tatttttcaa tttcaaaaac gttaattcct
    45541 ataatgtgtg tgttccaagt attcttgata gaacatatat ttagaattcg aaatagaatg
    45601 atgcagatag gtgaaattat aattattgtt gcttctataa tattatttat tgatagtata
    45661 ttgagtttgt aacaaaaggc ttctctataa aatcaaattt tccagatatc tactgaagct
    45721 gatttatttc ttcatctttc ttctactacc tttgtcacta aatttgacag acacatattg
    45781 ctgatacaac ctctctacct ataatctcac agttaacctg aggctagttt catagtttgc
    45841 tatttgattt tcgttgataa aaaaaatgct cctccaagac ggaagagcat tttttattgt
    45901 gattcttaca catttacttc ctagttttgc aggaagtcta gtataccatt ttttaaaaga
    45961 agagtaaaaa agcaagggta gtttcttttt tgagaattgt ctaaaagttt gatataatgg
    46021 tagttatgaa tagaataaga gtcagcaaaa gggttgaaaa gaagcttgct aaggggctag
    46081 ttttactaga agccagtgat cttgagaatg tcaatcttaa ggatcaggaa gtagaggtgc
    46141 agggtcagga aggaaacttt cttgggactg cctacctttc tcagcaaaac aagggcttgg
    46201 gctggtttgt cagcaaagac aaggtggcct tcaatcaagc tttctttgaa acgttgttta
    46261 gaaaagccaa agaaaagaga agcgcctact atcaagatga tttaacaact acctatcgtc
    46321 tctttaatca agagggagat ggctttgggg gtctgacagt ggacctttat ggcaactacg
    46381 ccgtcttttc ttggtataac tcttatgttt atcagattcg tcagactata tcagaagcct
    46441 ttagacaggt tttccctgag gttttagggg cttatgagaa aatccgcttt aaaggtttgg
    46501 actatgaatc tgcccatgtt tatggtcaag aagcacctga ctttttcact gttttagaaa
    46561 atggtgtcct gtatcaagtc tttatgaatg atggcttgat gacaggaatt ttcctagacc
    46621 agcatgaggt tcgcggtagt ttagttgacg gcttgactat gggtaaatcc ttgctcaata
    46681 tgttttccta cacagcggct ttttcagtag ctgcggccat gggaggagct agccagacaa
    46741 cttctgttga tctagccaaa cgttcacgag aattgtctca agcgcatttt caggcaaatg
    46801 ggctcagcac agacgagcat cgttttatag tcatggatgt ctttgagtat ttcaaatatg
    46861 ccaaacgcaa agacttgacc tacgatgtga ttgtcctaga tccgcctagc tttgctcgga
    46921 ataaaaaaca aactttctct gtggccaagg attatcacaa gttgatttcc cagagtcttg
    46981 agattttaaa tccgggaggg attatcattg ccagtaccaa tgctgccaat gtttcccgtc
    47041 agaaatttac agaacaaatt gataaaggct ttgcaggaag aagttaccag attttaaaca
    47101 aatatggtct tccagcagat tttgcctata ataaaaaaga tgaaagtagt aattacctca
    47161 aggtgattag tatgaaggtt agtaaatgaa attaatcgtt tcagtaatgc caagaagttt
    47221 agaggaggct caggctctgg atgccacgag gtacctggat gccgacatca ttgaatggcg
    47281 tgccgactat ctgcctaaag aagcgatttt gcaggtagct ccagccattt ttgaaaaatt
    47341 cgcaggccgt gagttggttt tcacgctacg aactcgctcc gaaggtggag aaatcgacct
    47401 ttctccagaa gagtatatcc atctaatcaa ggaagttgcg caattctatc aaccagacta
    47461 tattgatttt gagtactata gctacaagga tgtttttgag gaaatgctgg acttcccaaa
    47521 tcttgttttg agttaccata atttccaaga aacacctgag aacatgatgg aaatcttgtc
    47581 agagttgacg atcctaaatc caaaacttgt taaggttgcg gtgatggctc acacggagca
    47641 ggatgtctta gacttgatga actatacacg aggctttaaa accctcaatc ctgaacagga
    47701 atatgtgacc atttctatgg gtaaggtggg caaggtctct cgtatcactg cggatgtgac
    47761 tggttcgagt tggtcttttg ccagtctgga tgaggttagt gcccctgggc agatttctct
    47821 agctagcatg aaaaaaatca gggagatttt ggatgaagct tgatggctat acacgtttag
    47881 ctgcagttgt tgccaatcct attaagcatt ctatttctcc cttcatccac aatagagcct
    47941 ttgaggcgac agctaccaac ggtgcttatg tggcttggga gattgaagcg agtgacttgg
    48001 cagaaacagt ggccaatatt cgtcgctacc agatgtttgg catcaatctg tccatgccct
    48061 ataaggagca ggtgattcct tatttggata agctgagcga tgaagcgcgc ttgattggtg
    48121 cggttaatac ggttgtcaat gagaatggca atttaattgg atataataca gatggcaagg
    48181 gattttttaa gtgcttgcct tcttttacaa tttcaggtaa aaagatgacc ctgctgggtg
    48241 caggtggtgc ggctaaatca atcttggcac aggctatttt ggatggcgtc agtcagattt
    48301 cggtctttgt tcgttccgtt tctatggaaa aaacaagacc ttacctagac aagttacagg
    48361 agcagacagg ttttaaagtg gatttgtgtg ctttagagta tgtttctgaa ctgcaagcaa
    48421 ggattgccga gtcggatttg ctagttaatg ccaccagtgt gggcatggat ggccaatcct
    48481 ctcctgttcc tgaaaacata gtcttaccag aaactctctt agttgcagat atcatatacc
    48541 aaccctttga aacaccgttt ttgaaatggg ctagaagtca gggcaatcca gcagtcaatg
    48601 gtctgggaat gttgctatat caagctgcag aagcttttca actgtggaca ggcaaggaaa
    48661 tgccgacaga agagatttgg cagtctttaa cagaaaaata ccaataaaga aagggagact
    48721 ctcctatgaa aatcagaatc gatattcctc atcatcctta tgatattcag attgaaaaag
    48781 gttgtatggc ccaggctggt cagtggttgc gagaactctg gcaaccgcaa aaggtagtca
    48841 ttgtgacaga taaccatgta gcctctctct atgcagagaa ggtcaagctc agcctagaag
    48901 atgctggttt tcaggtagct gtttttgatt tcttagaagg tgaagaaaga aagaatttaa
    48961 ctactgttca gaaagtctat gaatttctag tcaagcaagg tctgactcgt agcgatggaa
    49021 tcgttgctct tggtggtggc gttgttgggg acctggctgg atttgtagcc tctacctata
    49081 tgcggggtat tcactttgtt cagattccga ctagtttgac agctcaggtt gattcttcta
    49141 tcggtggaaa gacaggcgtt aacacaccat ttgctaaaaa tatggtgggg acctttgccc
    49201 aaccagatgg ggttctgatt gatccacttg ttcttgaaac cctcggaaaa agagagttga
    49261 ttgaagggat gggtgaagtt atcaagtatg gcttgattga ggatccagaa ctgtgggctc
    49321 tcttgacggg gctgaatggt tctgttgaga gcattttgga acatgcagag accttgattg
    49381 aacattcttg tcaggtgaag cgcaagatgg tggttgaaga tgagttggac aatggtattc
    49441 gtctttacct caattttggc cacactattg gccatgccat cgaagcgact gccggttatg
    49501 gcaaggtcat gcatggagag gctgttgcca tgggaatggt acagatttcc aagattgctg
    49561 aggaaaaagg cctcatgcca gctggcatta cccaatctat cacagagatg tgtcagaaat
    49621 tcggcttgcc tgttgactat gaaaattggg aagttgacaa gctttatcag gctcttactc
    49681 atgacaagaa agcgcgtggt aacaccttga aattggtctt ggtgccagag cttggttcag
    49741 cgaccattca tccagtttct ctggaagaga tgaaagacta cttggtaaaa taaggagagt
    49801 gtatgagata tttaactgca ggagaatcac acggcccccg tctaacagct attattgagg
    49861 gaattccagc tggacttcca ttgacagctg aggatatcaa tgaggacctt agacgccgtc
    49921 agggtggcta cggtcgtggt ggtcgtatga agattgagag tgaccaggtt gtctttactt
    49981 cgggcgttcg ccacgggaag acgacagggg cgcctattac tatggatgtc atcaataagg
    50041 accaccagaa atggctggac atcatgtctg cggaggacat tgaagaccgc cttaaaagca
    50101 agcggaaaat tactcatcct cgcccaggtc atgccgattt ggttgggggg attaagtacc
    50161 gttttgatga tttgcgaaat tctttggagc gttcatcagc tcgtgaaacc accatgcggg
    50221 tggcagttgg tgcagtagcc aaacgtctct tggctgagct ggatatggag attgccaacc
    50281 atgtcgtggt ctttggtggc aaggaaatcg atgttcctga aaatctgaca gtcgctgaaa
    50341 ttaagcaaag agctgcccag tctgaagttt ctattgtcaa ccaagaacga gaacaggaaa
    50401 tcaaggacta tattgaccaa atcaaacgtg atggtgatac catcggtggg gttgtggaga
    50461 cagtcgtcgg aggcgttcca gttggtcttg gttcctatgt ccaatgggat agaaaattgg
    50521 atgcaagatt ggctcaagct gttgtctcta tcaatgcctt taaaggggtg gaatttggtc
    50581 ttggctttga ggctggttat cgtaaaggca gccaagttat ggatgaaatt ctctggtcta
    50641 aagaagacgg ttatactcgc cgtaccaata atctaggtgg ttttgaaggt ggtatgacta
    50701 atgggcaacc catcgttgtt cgtggggtta tgaaacccat tcctactctt tataaacctc
    50761 ttatgagtgt ggatatcgaa acccacgaac cttacaaggc aaccgtggag agaagtgatc
    50821 cgactgctct tccagctgca ggaatggtca tggaagcagt tgtagcaacg gttctggcgc
    50881 aagaaatcct cgaaaaattc tcatcagata atcttgagga actaaaagaa gcggtagcca
    50941 aacaccgaga ctatacaaag aactattaag gagttcctat ggcaaaaaca atctatatcg
    51001 caggtcttgg gttgattgga gcctctatgg cacttggtat caaacgcgat catccagatt
    51061 atgaaatttt aggttataat cgtagtcaag cttcgagaga catcgccttg aaagaaggca
    51121 tgattgaccg tgcaacggat gattttgcta gttttgctcc tttggcagat gtcattatcc
    51181 tcagcttgcc aatcaaacaa actattgctt tcattaagga gttggccaat ttggatttgc
    51241 gagaaggcgt tattatttca gatgctggtt cgaccaagtc aaccattgtg gatgcggcgg
    51301 agcagtattt ggctggcaag tctgttcgct ttgtcggggc ccatcccatg gctggtagtc
    51361 acaagacagg ggctgcttcg gcagatgtca atctttttga aaatgcctat tatatcttta
    51421 caccttcaag cctgacaagt caggacacgc ttaaggaaat gaaggatctg ctttcaggtc
    51481 ttcatgctcg ttttatcgag attgatgcca aggagcatga tcgtgtcact tctcagatta
    51541 gccattttcc tcatattttg gcttctagtc tcatggagca gactgcggtc tatgctcaag
    51601 agcatgagat ggcaaggcgc tttgcggcag gtggttttcg agatatgacc cgaattgcgg
    51661 aaagcgagcc aggaatgtgg acctccattc tcttgtccaa tagcgagacc attctggata
    51721 gaattgagga tttcaaggaa cgtttggaag cgattggtca ggccattagt aagggagatg
    51781 aagagcaaat ttggaacttt tttaaccaag cgcgtgaaca acgccagaca atggaaatcc
    51841 ataagcgtgg tggtgtggat agctcttacg acctctatgt tgacgttcct gatgaagaag
    51901 atgtcatcct gcggattttg gaactgctac gtgggacttc cttggttaac atccacatca
    51961 acgaggaaaa tcgtgaggat attcacggaa tcctacaaat ttcatttaaa aatgctcaag
    52021 acttggaaag agccgagcat ctcataacaa aaaataccga ctatacagtc gtcattaaat
    52081 aaggagaaga acatgtcaaa tatttacgat agtgcaaacg aactcagtcg cggtctacgc
    52141 ggattaccag aatacaaggc tgttaaagca gctaaagatg cgattgcagc agatgctgag
    52201 gcaagcaaaa tctttacaga atatcttgcc tttcaagagg aaattcaaaa actagcacag
    52261 acaggtcaaa tgccagatgc gtccttccaa gctaagatgg aaggctttgg taaacagatt
    52321 caaggaaata gcctcttgtc agaattcttt accaagcaac aacaattggc catttacctt
    52381 tctgacattg aaaaaattgt tttcgaacca gtttcagaat tgctgaaata agaaaagaac
    52441 tatcctaaag tcaggaattt ttaaggaatt tctggctttt tatgataaaa taggtaaaag
    52501 tattgcaagt atgaggtcca gtatgaaact aaaaacaaac attcgccatt tacatggtag
    52561 tatccgcgtc ccaggtgaca agtctatcag ccaccgttcc attatctttg gaagtttggc
    52621 tgagggtgag accaaggttt atgatattct gcgaggtgaa gacgttcttt cgaccatgca
    52681 ggtttttcgt gaccttggtg ttgaaattga ggataaagat ggggttatta ccgttcaagg
    52741 tgtaggcatg gctggcttaa aagcgccgca aaatgccctt aatatgggaa attctggcac
    52801 ctcgattcgc ctgatttcag gtgtccttgc tggtgcagat ttcgaagtag agatgtttgg
    52861 agatgatagt ctttccaaac gtcctatgga ccgtgtgacc cttccactga aaaaaatggg
    52921 cgtcagcatc tcagggcaaa ctgaacgaga cttgcctccc cttcgcttaa aagggacgaa
    52981 aaacctaaga cctattcatt atgagttgcc aattgcctct gcccaagtca agtcagcctt
    53041 gatgtttgca gccttacaag ctaaggggga gtcagttatt atcgaaaaag agtacacccg
    53101 taatcatact gaagatatgt tgcaacaatt tggtggtcat ttaagtgtgg atggtaagaa
    53161 aatcacagtc caagggccac aaaaattgac gggacagaag gtggtcgtac caggagatat
    53221 ttccagtgca gccttttggt tagtcgcagg tttgattgct ccaaattctc gtctagtgct
    53281 gcagaatgtg gggataaacg aaactcgcac cggtattatt gatgtcattc gtgccatggg
    53341 tggaaaattg gaaataactg aaatcgatcc agtcgctaaa tctgcaacct tgattgttga
    53401 gtcttctgac ttgaaaggaa cagagatttg tggcgctttg attccacgtt tgattgatga
    53461 attgcctatt attgccctac ttgcgaccca agcccaaggt gtaacagtta tcaaggatgc
    53521 tgaggagctc aaggtcaagg aaacagaccg tattcaggtt gtggcagacg ccttaaatag
    53581 tatgggagca gatattactc ctacggcaga tgggatgatt atcaaaggaa aatcagctct
    53641 tcacggtgct agagtcaata cgtttggtga ccaccgtatc ggcatgatga cagctatcgc
    53701 agccctattg gttgcagatg gagaggtgga gcttgaccgt gcagaagcca tcaataccag
    53761 ctatcctagt ttctttgatg atttggagag cttgattcat ggctaaggtg ttattagggt
    53821 ttatgggggc tggaaaatcg actattgcaa gaggcttgga ccctaattac cttgatatgg
    53881 atgctctgat tgagaagcgc ctaggtatgt ccattgcgaa ttttttcgct gaaaagggag
    53941 aagcagcctt tcgtcaggta gaatcagaag tcctagctga tttattacaa agagaccaag
    54001 tcgtgtcaac tggaggagga gtggttattt ctcagagaaa tcgtgactta ctcaagacta
    54061 atacagataa catctacctg aaagcagatt ttgaaaccct ctacctacgt atcgcagctg
    54121 ataaggacaa tcagcgaccg ctttttctaa ataatagcaa ggaagaacta gtagctattt
    54181 ttcaagaaag acaggcttgg tatgaggaag tggctagtcg ggttttggat gtgaccaagc
    54241 taagcccaga ggaaattata gaggaactaa gatgaaaatt gcttatctag gtcccaaagg
    54301 atcattttca caccacgttg tgcagacagc ttttcctcat gaggaattgc aggcttttgc
    54361 caacattaca gatgtcatca aggcttatga gcaaggatta gtggactatt ctgtggtgcc
    54421 agttgaaaat tctattgagg gtagtgttca tgaaaccttg gactatcttt ttcatcaggc
    54481 tcacatccaa gcagtagcag aaatcgttca gcctattcat cagcagttga tggtggttcc
    54541 aggccatact aagattgaaa agattttttc acatccacag gccttggctc aaggaaagaa
    54601 attcatcgat gaacaatatc cagaggctca aatcgaggta acagctagta cagcttatgc
    54661 ggcccgtttt atttccgaac atccagatca gccctttgca gcaattgcac ctagaagttc
    54721 tgctgaagaa tatggattgg aactgattgc cgaggatatt caggaaatgg aagccaattt
    54781 cacacgtttc tggcttctag gagctgaaaa gcctagtatt cccttgcaag cacaaactga
    54841 aaagatgagt ttggccttga cattacctga caaccttcca ggtgcacttt ataaggccct
    54901 gtcgaccttt gcttggcgag gaattgactt gacaaaaatt gaaagtcgtc cactcaagac
    54961 agcactgggt gaatactttt tcattatcga tgtggattat accgataagg acttggtcca
    55021 ctttgcccaa aaagaattag aagcgattgg aatccagtat aaaattctgg gtgcctatcc
    55081 tatttatcca atatcagacc atggaaagga gagaagatga gtaaagaaaa tcccttaagt
    55141 catcatgagc agttgcgtta tgattatttg ctaaaaaata ttcactatct caatgagaga
    55201 gaaaaaaatg agtttgtcta tttgcaagaa aagctaactc ttgctagggg aaatagtagc
    55261 tctagcttgg aacaagaaag agaagagcag gttgacttac caagctatgc gaaccggagt
    55321 cgctcacaat ccaaatcaca agcactctct ttccctccaa aaaagaaaag acggaagctc
    55381 cgtcttaaac gaatttttat ggtgattttt tcacttttgg tctgtgtggc tttggccatg
    55441 gtattcatgt ttttgcgtgg ttaccaagat gctagcgcaa agaaaactgc tgatgcccgg
    55501 gcagctcaag tagaagtctt taatggtcag gacactagag atggagttaa tattttaatc
    55561 atgggtactg atggtcgaat cggccagaac agtgttgaga cacgaactga ctctattatg
    55621 gtattaaatg tcgggggctc agataagaaa atgaagctag tcagtttcat gcgtgataat
    55681 ttggtctata tagatggtta tagtcaagtg attaacggta gaaaacagac agataacaag
    55741 ttaaacgtag cctacgagtt aggagaacaa gaagggcaaa aaggggcaga aatggttcgc
    55801 caagtcttga aagataattt tgacttggac attaagtact acgccttggt tgatttccag
    55861 gcctttgcca cagcgattga cacgcttttc cctgatgggg tgacgattga tgctcaattt
    55921 tcaacattga atgggcgtcc cctaacagaa gctacagtcg gagatgattt atacgctacc
    55981 gagactgagt ctccaaccca aaccattaaa gtcggaaaac agcagatgaa tggctcgacc
    56041 ctgctcaatt atgctcgttt ccgtgatgat gatgaggcgg attacggccg tacaaaaaga
    56101 cagcaacaag ttttaacagc aattttagag caaattaaag atcccactaa acttttcact
    56161 ggttctgaag ctcttggaaa ggtttttgct atgacctcaa ccaacgtacc ctatactttc
    56221 ctcctaacaa acggtttatc tgttttggat ggagcaaaaa atggtattga aaaattgacg
    56281 attccagaac tgggtgactg ggtagatgcc tatgatgttt atggaggctt gggcttgctg
    56341 gttgatcaaa acaaatatca aaccaagctc gctcaaatgg gcttgagata agataatact
    56401 caatgaaaat caaagtgcaa attaggaagc tagccgcagg ctgctaaaaa cacagttttg
    56461 aggttgtaga taagactgac gaagtcagtt acctatacct acggcaaggt gaagctgacg
    56521 ttgtttgaag agattttcga agagtataag acagaaaaat caaagtttga tagctatttg
    56581 gatagcagtc aggctttgat tttttacagt ctgcaataga ttttcacccc ttgtttgtgg
    56641 tataatgaaa cgatacgata gaaagaataa tgaacaatat gactgattta aaagcaattc
    56701 aggctcgtag tctggagatg gctgaatatt ttgtggtctt ttgtaaagaa catgatttgc
    56761 tctgttatct ctgtggcgga ggcgctattg gtgcccttcg aaacaaggga tttattcctt
    56821 gggacgacga cctagacttt tttatgcctc gtaaagatta tgagaaatta gcagaattat
    56881 ggcctcgtta tgcagatgaa cgttatttct tgtcaaagag tcacaagaat tttgttgatc
    56941 gtaatctttt tattaccatt cgtgacaagg aaaccacctg tatcaagcct tatcagcagg
    57001 atttggattt gccacatggt ctggccttgg atgttttgcc tttggattat tatccgaaaa
    57061 atccagctga gcggaaaaaa caggttcgtt gggccttgat ttattcactc ttttgtgcgc
    57121 aaactattcc agaaaagcat ggtgctctca tgaaatgggg aagtcgcatt ttactgggtt
    57181 tgactccaaa atctctccgt tatcgcatct ggaaaaaagc tgagaaagaa atgactaagt
    57241 atgatttggc tgattgtgat ggcattacag aattatgctc aggtcctggc tacatgagaa
    57301 acaagtaccc aatcacatct tttgaagaca atcttttctt gccatttgaa ggaacagaga
    57361 tgcctattcc aatcggctat gatgtctatc tcagaactgc ttttggggat tatatgacgc
    57421 ctccaccagc agacaagcag gtaccgcatc atgatgctgt catcgctgat atggataagt
    57481 cttatacaga atacaaggga gaatatggtg gctaagaaaa aaatcttatt ttttatgtgg
    57541 tctttttctc ttggaggtgg tgcagagaag attctatcaa ccattgtttc aaatctggat
    57601 ccagaaaagt atgatattga tattcttgaa atggagcact ttgacaaggg atatgaatct
    57661 gttccaaagc atgtacgcat tttaaaatcc cttcaagatt atcgccaaac cagatggtta
    57721 cgagcttttt tgtggagaat gagaatttat tttccaagac tgactcgtcg tttgcttgta
    57781 aaagatgatt atgatgttga agtttctttt accattatga atccaccact gttgttctct
    57841 aaaagaagag aagtcaagaa gatatcttgg attcatggaa gtattgaaga acttcttaag
    57901 gatagctcta aaagagaatc acatagaagc cagttggatg ctgcgaatac aattgtaggg
    57961 atttcaaaaa agaccagcaa ttctatcaag gaagtttatc cagattatgc ttctaaatta
    58021 cagacaatct acaatggata tgattttcag actattctag aaaaatctca agagaagatc
    58081 gatatcgaga ttgctcctca aagtatctgt actatcggac ggattgagga aaataagggt
    58141 tctgaccgtg tagtggaagt gatacgatta ttacaccaag agggaaaaaa ctatcatctc
    58201 tattttatcg gggctggtga tatggaagag gaactgaaaa aacgagtcaa agagtatgag
    58261 attgaggact atgtacattt ccttggttat caaaaaaatc cttatcagta tttatctcag
    58321 acgaaagttc tcttgtctat gtctaaacaa gaaggctttc ctggagtgta tgtggaggcc
    58381 ttgagtctgg gactcccttt tatctctacg gacgttggag gggctgagga attatcccaa
    58441 gaaggacgat ttggacaaat cattgagagc aatcaagagg cagctcaggc gattactaat
    58501 tacatgactt ctgcctcaaa ctttaatgtc gatgaggcta gccaattcat tcaacaattt
    58561 acaattacaa aacaaatcga acaagtagaa aaactattag aggagtagca tggaaactgc
    58621 attaattagt gtgattgtgc cagtctataa tgtggcgcag tacctagaaa aatcgatagc
    58681 ttccattcag aagcagacct atcaaaatct ggaaattatt cttgttgatg atggtgcaac
    58741 agatgaaagt ggtcgcttgt gtgattcaat cgctgaacaa gatgacaggg tgtcagtgct
    58801 tcataaaaag aacgaaggat tgtcgcaagc acgaaatgat gggatgaagc aggctcacgg
    58861 ggattatctg atttttattg actcagatga ttatatccat ccagaaatga ttcagagctt
    58921 atatgagcaa ttagttcaag aagatgcgga tgtttcaagc tgtggtgtca tgaatgtcta
    58981 tgctaatgat gaaagcccac agtcagccaa tcaggatgac tattttgtct gtgattctca
    59041 aacatttcta aaggaatacc tcataggtga aaaaatacct gggacgattt gcaataagct
    59101 aatcaagaga caaattgcaa ctgccctatc ctttcctaag gggttgattt acgaagatgc
    59161 ctattaccat tttgatttaa tcaagttggc caagaagtat gtggttaata ctaaacccta
    59221 ttattactat ttccatagag gggatagtat tacgaccaaa ccctatgcaa agaaggattt
    59281 agcctatatt gatatctacc aaaagtttta taatgaagtt gtgaaaaact atcctgactt
    59341 gaaagaggtc gcttttttca gattggccta tgctcacttc tttattctgg ataagatgtt
    59401 gctagatgat cagtataaac agtttgaagc ctattctcag attcatcgtt ttttaaaagg
    59461 ctatgctttt gctatttcta ggaatccaat tttccgtaag gggagaagaa ttagtgcttt
    59521 ggccctattc ataaatattt ccttataccg attcttatta ctgaaaaata ttgaaaaatc
    59581 taaaaaatta cattagaacg ggggtgacca agtgattgat gggaaacgat tattatttag
    59641 tttgaccata gtcagttata ccttgacgct agtaagtgga attgtgtatc tgtttaataa
    59701 taataatgtt agcttacttt ctactttatt gttcttgttg gttagtagct taattgcttg
    59761 ttggaatgat atcaagtatt acttaatcca ttttattttc tatttaacca tttttgtatt
    59821 tctggtatca agaccgacca ttgattattt tagggatggt gctttggata cctatcatcc
    59881 aatagcctat cgttttgcct ttatagttgt catggtttcg attctgggct tgaccacagg
    59941 aggcgtcctg gctcgttact tcatagctag gaagaaaata aaagtagcaa atataggaaa
    60001 ttctctaaaa gaggtttata tcaagcggtt acgctttgta tcactaggag tttttcttct
    60061 aacttatcct ttctatttca ttcggttatt tgaacggctc ttgtatcgtt tgcagacttc
    60121 ctactatgcc tactatgcaa attttgaaag taaactgcct tattttacct acattttgtc
    60181 tacctttacg gtctatgcaa tgtgtatgta tctggcaacc aagccaaaga aattgcaggc
    60241 cacagcagtg cttgtctcct ttattgcagc taatactatt catttggcaa ttgggacacg
    60301 aaatcccttt attttaagta ttttatttgc ttttgtttat tactttatgc gggagcaaac
    60361 tgaaaaagga aaatggattg ggtttaaaga aaagttagcg atttttgtag gttctcctat
    60421 tctcatgtta gcgatgggag tactcaatta tgtacgggat aatgtccaag tttcccatac
    60481 aggtttctgg gatatcttac ttgactttat ctataaacaa gggactagtt ttggtgttct
    60541 ggctcgaggt tttctattta acagtagcct cccttaccga gatttccgta attttacttt
    60601 tggtcctgtt cttgattatt ttgcaagggg gagtttggga gccattttcg gaggaaaagc
    60661 ctttgaacat acaaccaata gtgtggaact agctattgat agtaatagtt atgcccacaa
    60721 tctatcctat cttgtcttga acaaggaata cttgaaaggg catggtatcg gaagtagtta
    60781 tatcatggag ttgtataccg actatggtat gattggagtc tttctgctta gtttcttact
    60841 cggcgtatta tttatagcca tgctgcaagt agcctatcgc tcaaggacaa tcctatttgc
    60901 tttatcccta ctcatcttga ataatctatt ctttatgcca agaagcagct tttcagaaag
    60961 tttcttcaat ttatttacaa tgcaattctg gggaattgtt cttgtgatta tatttgtagc
    61021 aaaaatgctt acaaaggaaa actagtatct actaaacaaa ggagaaaaaa atcatgtttg
    61081 aacattattc agtagctgat ttgtttgcaa atctttataa aaagcgaaaa gcaaatattt
    61141 tagctctcat cgctttattt gctctcattg ctgtaccatt tacaattaaa gcagttagga
    61201 ataaaaatac tgtcaaagat acaacaagtt attcaactta tcttatctat aaaatcactc
    61261 ctccaaaaga gtcggccaaa acgattttga atcatcaaat tggtggttat agtgattttt
    61321 atgggaaatt gattgatggt aatttgaatg gagcttatct tttcaatgat gtagaaccca
    61381 gtgagttgaa aaaaattgcc agtgaattag acacgacaga aacaaccttg aaaaattcaa
    61441 cgaatgacta ttggtggaaa aaattgaccg tctactatat gattgacgat gcaggggttg
    61501 gtgtgaaaat tttgacatca agtaaagatg ccaatgactt gttagagaaa aaaattgatg
    61561 ggttgattga gaaatttaaa catgcttatg caaatgtgaa aattgaaaaa ctggaaacca
    61621 tcaactctaa agaattgaac gcaaatggtg aaacagcgct tggcttaaat gtgaaaaatc
    61681 tgattcttcg tttagttgtt attggagtgg tttgtgtgat tttggttgtg atgggaaatg
    61741 tgttagttta tctctttaat ccaacaatca atagagtagg tgatttttct cagtatcaaa
    61801 ttgattttgt aacagagatt acaacaattg ctaacctagc agatgttttg tcatacaaaa
    61861 atactggaca ggaattgacc atcgttagct caaataaagc tatcctagat aaattgaaac
    61921 agagtcaaga agctttaaaa ggaatgcatt ttgtagattt acaggatgta tcatctcttt
    61981 tggaaagaga tacagtcctt cttgttgaag agtacggagt gactcgttat aagaaatttg
    62041 agcaaagtct tcaaattctc agaaacttaa atcgttctat cctcggtgta gcaaccttta
    62101 aattataagt attctgatgt ataaggtctt caaagtcggc taagagccga ttttgaaggc
    62161 tttttctatc tgtctgcaga aattttcttt tgataaaatc gtaaaaatct agtataatag
    62221 atagaactga aagtatgagg ttactagcaa tgaaaatgaa acaaattagt gatacaactt
    62281 taaaaatcac gatgtcttta gaggatttga tggatcgtgg aatggagatt gctgactttc
    62341 tcgttcctca agaaaaaaca gaagagttct tttatgctat cttggatgag ctagagatgc
    62401 ctgatagctt tctggataca ggcatgttga gcttccgtgt gactccaaaa cctgataagg
    62461 tagatgtctt tgtgaccaag tcaaagattg accaaaatct agattttgaa gacttatcgg
    62521 atttgccaga tatggaagaa ttggctcaaa tgtctccaga tgaatttatc aaaaccctgg
    62581 aaaaaagcat cgcagacaaa accaaggatg atatcgaagc cattcaatct cttgagcaag
    62641 ttgaagccaa ggaagaagag caagagcagg ctgaacaaga agctgagagt aagaaagaac
    62701 cttacatcta ctacatcctt tcttttgcta agttggctga cttggtagct tttgccaaga
    62761 cagtgacttt tgaaatggaa acttctgaac tctacaaaat gaacgagcgc tattatttga
    62821 ccattttagt ggatattgaa aatcatccaa gcccatatcc agcttggctg ttggcccgta
    62881 tgcgcgagtt tgcagaggat agtgatatca gtcgctcagt cttacaagag tatggtcaag
    62941 tcttgatgag tcacgatgca gtgctcaatc tgcaaaaaat cggctaatcc tttctggaaa
    63001 gctatttcag attttaagaa gagcgaatcg tctgattcgt tttttctttt tatactgaaa
    63061 tagtgattta ctataatagg aattttcaca aaattctgtt ataatggcta tattagaaaa
    63121 tttcgaggag ataaagatga cagttaaaat tgctttacta ggatttggta ccgttgcaag
    63181 tggtgtgcct ttcctcctaa aggaaaatgg aggaaaaatc aatcaatcag cacattcaga
    63241 tatcaaagtt gctaaggtat tggtcaagga tgaagatgaa aaaaatcgct tgcttgcagc
    63301 agggaatgac tttaactttg taaccaatgt ggatgatatt ttatcagacc aggatattac
    63361 tatcgtagtg gaattgatgg ggcgtattga gcctgctaaa acctttatca ctcgtgcctt
    63421 ggaagctgga aaacacgttg ttactgctaa caaggacctt ttagctgtcc atggcgcaga
    63481 attgctagaa atcgctcaag ctaacaaggt agcactttac tacgaagcag cagttgctgg
    63541 tgggattcca attcttcgta ctttagcaaa ttccttggct tctgataaaa ttacgcgcgt
    63601 gcttggagta gtcaacggaa cttccaactt catggtgacc aagatggtgg aagaaggctg
    63661 gtcttacgat gatgctcttg cggaagcaca acgtctagga tttgcagaaa gcgatccgac
    63721 gaatgacgta gatgggattg atgcagccta caagatggtt attttgagcc aatttgcctt
    63781 tggcatgaag attgcctttg atgatgtagc ccacaaggga atccgcaata tcacaccaga
    63841 agacgtagct gtagctcaag agcttggtta cgtagtgaaa ttggttggtt ctattgagga
    63901 aacttcttca ggtattgctg cagaagtgac tccaaccttc ctacctaaag cgcacccact
    63961 tgctagtgtg aatggcgtaa tgaacgctgt ctttgtagaa tctatcggta ttggtgagtc
    64021 tatgtactac ggaccaggtg cgggtcaaaa accaactgca acaagtgttg tagctgatat
    64081 tgtccgtatc gttcgtcgtt tgaatgatgg tactattggc aaagacttca acgaatatag
    64141 ccgtgacttg gtcttggcaa atcctgaaga tgtcaaagca aactactatt tctcaatctt
    64201 ggctctagac tcaaaaggtc aggtcttgaa gttggctgaa atcttcaatg ctcaagatat
    64261 ttcctttaag caaatccttc aagatggcaa agagggtgac aaggcgcgtg tcgttatcat
    64321 cacacacaag attaataaag cccagcttga aaatgtctca gctgaattga agaaggtttc
    64381 agaattcgac ctcttgaata ccttcaaggt gctaggagaa taagatgaag attattgtac
    64441 ctgcaaccag tgccaatatc gggccaggtt ttgactcggt cggtgtagct gtaaccaagt
    64501 atcttcaaat tgaggtctgc gaagaacgag atgagtggct gattgaacac cagattggca
    64561 aatggattcc acatgatgag cgtaatctct tgctcaaaat cgctttgcaa attgtaccag
    64621 acttgcaacc aagacgcttg aaaatgacca gtgatgtccc tttggcgcgc ggtttgggtt
    64681 cttccagctc ggttatcgtt gctgggattg aactagccaa ccaactgggt caactcaact
    64741 tatcagacca tgaaaaattg cagttagcga ccaagattga agggcatcct gacaatgtgg
    64801 ctccagccat ttatggtaat ctcgttattg caagttctgt tgaagggcaa gtctctgcta
    64861 tcgtagcaga ctttccagag tgtgattttc tagcttacat tccaaactat gaattacgta
    64921 ctcgcgacag ccgtagtgtc ttgcctaaaa aattgtctta taaggaagct gttgctgcaa
    64981 gttctatcgc caatgtagcg gttgctgcct tgttggcagg agacatggtg accgctgggc
    65041 aagcaatcga gggagacctc ttccatgagc gctatcgtca ggacttggta agagaatttg
    65101 cgatgattaa gcaagtgacc aaagaaaatg gggcctatgc aacctacctt tctggtgctg
    65161 ggtcgacagt tatggttctg gcttctcatg acaagatgcc aacaattaag gcagaattgg
    65221 aaaagcaacc tttcaaagga aaactgcatg acttgagagt tgatacccaa ggtgtccgtg
    65281 tagaagcaaa ataaagaata gaagatagga tggggaaact cttgaccaga gggtttcata
    65341 tcctttttgt gaaaagaagt ttatactcaa tgaaaatcaa agagcaaact aggaagctag
    65401 ccgcaggctg ctcaaaacag tgttttgagg ttgtggatag aactgacgac gtcagctcaa
    65461 gacactgttt tgaggttgca gatagaactg acgacgtcag ctcaagacac tgttttgagg
    65521 ttgcagatag aactgacgac gtcagtaaca tatatacggt aaggtgacgc tgacgtggtt
    65581 tgaagagatt ttcgaagagt attagttaaa aacgtgataa aggagaaata aaaatgacag
    65641 aaatttatct agcaggtggt tgtttttggg gcctagagga atatttttca cgcatttctg
    65701 gagtgctaga aaccagtgtt ggctacgcta atggtcaagt cgaaacgacc aattaccagt
    65761 tgctcaagga aacagaccat gcagaaacgg tccaagtgat ttacgatgag aaggaagtgt
    65821 cactcagaga gattttactt tattatttcc gagttatcga tcctctatct atcaatcaac
    65881 aagggaatga ccgtggtcgc caatatcgaa ctgggattta ttatcaggat gaagcagatt
    65941 tgccagctat ctacacagtg gtgcaggagc aggaacgcat gctgggtcga aagattgcag
    66001 tagaagtgga gcaattacgc cactacattc tggctgaaga ctaccaccaa gactatctca
    66061 ggaagaatcc ttcaggttac tgtcatatcg atgtgaccga tgctgataag ccattgattg
    66121 atgcagcaaa ctatgaaaag cctagtcaag aggtgttgaa ggccagtcta tctgaagagt
    66181 cttatcgtgt cacacaagaa gctgctacag aggctccatt taccaatgcc tatgaccaaa
    66241 cctttgaaga ggggatttat gtagatatta cgacaggtga gccactcttt tttgccaagg
    66301 ataagtttgc ttcaggttgt ggttggccaa gttttagccg tccgatttcc aaagagttga
    66361 ttcattatta caaggatctg agccatggaa tggagcgaat tgaagttcgt tctcgttcag
    66421 gcagtgctca cttgggtcat gttttcacag atggaccgcg ggagttaggc ggcctccgtt
    66481 actgtatcaa ttctgcttct ttacgctttg tggccaagga tgagatggaa aaagcaggat
    66541 atggctatct attgccttac ttaaacaaat aaaacagaga gtggggcttc ccactttctt
    66601 catttctaga atatgaatag aagggattta tgaaacacct attatcttac ttcaaaccct
    66661 acatcaagga atcaatttta gcccccttgt tcaagctgtt agaagctgtt tttgagctct
    66721 tggttcccat ggtgattgct gggattgttg accaatcttt acctcaggga gatcaaggtc
    66781 atctctggat gcagattggc ctgctcctta tctttgcagt aattggcgtt ttagtggcct
    66841 tgatagctca attttactca gcaaaggcag cagtaggttt tgctaaggaa ttgacaaacg
    66901 atctttatcg tcatattctt tccttgccca aggacagcag agaccgtctg acaacttcta
    66961 gtttggttac tcgcttgact tcggatacct accagattca gactggtatc aatcaattcc
    67021 tgcgtctctt tttacgagcg cccattatcg tttttggtgc catttttatg gcttatcgaa
    67081 tctcagctga gttgactttc tggttcttag tcatggttgc cattttgacc attgtcattg
    67141 tagggttatc tcgattggtc aatcctctct acagtagtct cagaaagaaa acggaccaac
    67201 tggttcagga aacgcgccag caattgcaag ggatgcgggt tattcgtgct tttggtcaag
    67261 aaaaacgaga gttacagatt tttcaaaccc ttaaccaagt ttatgctaga ttacaagaaa
    67321 agacaggttt cttgtctagt ttattaatac ctctgaccta tctgattgtc aatggaactc
    67381 ttctcgttat tatctggcaa ggctatattt caattcaagg aggagtactc agtcaaggtg
    67441 ctctcattgc tcttatcaat tacctcttac agattttggt ggaattggtc aagctagcca
    67501 tgctgatcaa ttccctcaac cagtcctata tctcagccaa gagaatcgag gaggtctttg
    67561 cggaatctcc cgaaaacatc cattcagaat tagaacaaaa gcaagttacc agtggtcggg
    67621 ttttacaagt ccaagaattg acttttacct atcctgatgc ggcccagcct tctctgagag
    67681 acatttcctt tgatatgact caaggacaaa tccttggtat cattgggggg actggttctg
    67741 gtaaatcaag cttggtgcaa ctcttacttg gactttatcc agtagacaag gggaacattg
    67801 acctttatca aaatggacgt agtcctctta atttggagca gtggcggtct tggattgcct
    67861 atgtacctca aaaggtcaaa ctctttaagg gaactattcg ttccaacttg actttaggtt
    67921 taaatcaaga agtatctgac cagaaactct ggcaggcctt ggagattgcg caagctaagg
    67981 attttgtcag tgaaaaggaa ggacttttgg atgccctagt tgaggcaggg gggcgaaatt
    68041 tctcaggtgg acaaaaacaa aggttgtcta tcgcccgagc agtcttgcgc caagctccgt
    68101 ttatcatcct agatgatgca acctcggcac tggataccat tacagagtcc aagctcttga
    68161 aagctattag agaaaatttt ccaaacacga gcttaatttt gatctctcaa cgaacctcga
    68221 ctttacaaat ggcggaccag attctcctct tggaaaaagg tgagttgcta gctgttggca
    68281 agcacgatga cttgatgaaa tccagccaag tctatcgtga aatcaatgca tcccaacatg
    68341 gaaaggagga ctagaatgaa acgacaaact gtaaaccaga cgctcaaacg tttagccgta
    68401 gatttagcaa accatccctt cctccttttc ctagcctttc taggaactat tgcccaagtt
    68461 ggcttatcaa tttacctacc tattctgatt gggcaggtca ttgaccaagt cctagtggct
    68521 ggttcatcac cagttttttg gcagattttt ctccagatgc tcttggtggt aataggaaat
    68581 actctggtac aatgggccaa tcctctcctc tataatcgtc taatcttctc ttataccaga
    68641 gatttacggg agcgaatcat ccataaactc catcggttac cgattgcctt tgtagatagg
    68701 caaggtagtg gagagatggt tagtcgtgta accacggaca tcgaacagtt ggcagctggc
    68761 ttgaccatga tttttaacca atttttcatt ggtgttttga tgattttggt tagtattcta
    68821 gccatgctcc aaattcatct cctcatgact ctcttagtct tgctgttgac gccactgtcc
    68881 atggtgattt cacgctttat tgccaagaga tcctatcatc tcttccagaa gcaaacagag
    68941 acgaggggaa ttcagactca gttgattgaa gaatcgctta gccagcagac tataatccag
    69001 tccttcaatg ctcaaacaga atttatccaa agattgcgtg aggctcatga caactactca
    69061 ggctattctc agtcagccat cttttattct tcaacggtca atccttcgac tcgctttgta
    69121 aatgcactca tttatgccct tttagctgga gtaggagctt atcgtatcat gatgggttca
    69181 accttgaccg tcggtcgttt agtgactttt ttgaactatg ttcagcaata caccaagccc
    69241 tttaatgata tttcttcagt gctagctgag ttgcaaagtg ctctggcttg cgtagagcgt
    69301 atctatggag tcttagatag ccctgaagtg gctgaaacag gtaaggaagt cttgaccagt
    69361 gaccaagtta agggagctat ttcctttaaa catgtctctt ttggctacca tcctgaaaaa
    69421 attttgatta aggacttgtc tatcgatatt ccagctggta gtaaggtagc catcgttggt
    69481 ccgacaggtg ctggaaaatc aactcttatc aatctcctta tgcgttttta tcccattagc
    69541 tcgggagata tcttgctgga tgggcaatcc atttatgatt atacacgagc atcattgaga
    69601 cagcagtttg gcatggtgct tcaagaaacc tggctcacac aagggaccat tcatgataat
    69661 attgcctttg gcaatcctga agccagtcga gagcaagtaa ttgctgctgc caaagcagct
    69721 aatgcagact ttttcatcca acagttgcca cagggatacg ataccaagtt ggaaaatgct
    69781 ggagaatctc tctctgtcgg ccaagctcag ctcttgacca tagcccgagt ctttctggct
    69841 attccaaaga ttcttatctt agacgaggca acttcttcca ttgatacacg gacagaagtg
    69901 ctggtacagg atgcctttgt aaaactcatg aagggccgca caagtttcat cattgctcac
    69961 cgtttgtcaa ccattcagga tgcggattta attcttgtct tagtagatgg tgatattgtt
    70021 gaatatggta accatcaaga actcatggat agaaagggta agtattacca aatgcaaaaa
    70081 gctgcggctt ttagttctga ataagccatt ctcttttgaa agtttatgga cgaaaaaagt
    70141 tgccttcgag tgactttttt gttacaatag ctagaaaaat tgttcactgt aatactcaat
    70201 gaaaatcaaa gagcaaacta ggaagctagc cgtaggttgc tcaaaacact gttttgaggt
    70261 tgcagataga actgacgaag tcagctcaaa acactgtttt gaggttacag atagaactga
    70321 cgaagtcagt aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac
    70381 ttgtctttta gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg
    70441 tgatcaagat ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt
    70501 ctatgtcggt caagataagc cagcgttttt agagcaagct gagcagatta tagactatca
    70561 gggagcttgg attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct
    70621 gagagggatc cgagatgaca gcaatctcca tgaatggctc aatgactata tttggccagc
    70681 agaatctgag tttactcccg acatgactac caatgcggtc aaagaagccc tgacagagat
    70741 gctccagtca ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca
    70801 gcaaatttat caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt
    70861 ttcttcagag acagaaacaa ctgctgagac tataagtaga actcgatcca tcatagacga
    70921 aatcttaaaa tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag
    70981 ctgcagtaga gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct
    71041 ccatgtccat gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa
    71101 acgccccctt gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca
    71161 cggggtcgaa ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc
    71221 ccacaatcct atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca
    71281 aaaagcggga gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga
    71341 tatgtttgag gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag
    71401 ccagtttcca atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg
    71461 aatggaaaat cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca
    71521 accacaaggg aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc
    71581 agttaaatct agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg
    71641 tcaagtcctg acagtagaac tttaaaagaa aaattacgaa aaattttaaa aaaagtttgc
    71701 aaaaatcttg cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc
    71761 taagacagta ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa
    71821 aaagaagcgt attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc
    71881 cccaagcaaa ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa
    71941 agcggaacta gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt
    72001 agacgctcgt ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag
    72061 cgaagttgag tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg
    72121 tcttgaagat cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga
    72181 tgttatcgca ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat
    72241 taaaggtggt gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac
    72301 tcttccaaac cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg
    72361 caacgttgct cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta
    72421 agctacacag cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga
    72481 ggaaataaca atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat
    72541 ccttgaattg aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc
    72601 tcctgtagct gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga
    72661 cgttgaattg acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat
    72721 cactggtctt ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa
    72781 agaaggcgtt gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc
    72841 ttcagttact cttaaataat agagtatcgc aatttgattg cggaatccct atttaccagt
    72901 ctttgagagc gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa
    72961 ttctttggca ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc
    73021 ctttttttgt gtttcggagg taattatgca aaaggaagga cagtcatcac gtcaattcgt
    73081 gaagagtcat ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga
    73141 tgaaatggaa caagtaggtt taatccgatt tgatgaattt ggaaatgttg gaattttagt
    73201 cttggaggga caataatgaa gcgtattacc gctaatcaat atcagacatc agagcgttat
    73261 tataagctcc ccaaactttt atttgagagt gaacggtata agaatatgaa actggaggtt
    73321 aaggtggttt actcagtttt aaaagatcgg ttggagttgt ctttgagcaa aggttggatt
    73381 gatgaggatg gggctattta tttgatttat tccaattcaa atttgatggc acttttaggc
    73441 tgttcaaagt caaaattact ctccatgtga gtttgaagtg acatttttag atgattacca
    73501 taaaaaacat aactacccac tattttacga atcctatctt caaaacgtta tggaattcct
    73561 tgaaagtcaa gacataaaga atggggttga tgcctttgta gatgatcatc aaaatctcgt
    73621 ttttgtttta tatggacaag gctatcgagc cgagggaaaa gagggaatac ttacaaccca
    73681 agtaactgta aaagcttatg atgaagacaa gaaaccgatt aacttcgcaa atttattaga
    73741 ttccttaatt tattagattc cttaatcgtc tcagaatatc aaatggaacc gaatctttgg
    73801 gaggtctccc atgattgatc tctatctaag taaaaataga caaagaaatc aacttctttt
    73861 agatttcttc caaaactatg gcatagaggt atcttgtcat tcagtttctg aaatgacaaa
    73921 ggacaaatta attgagatga tgagctattc ttcagattgt tttgagtttt tatctcccaa
    73981 tttattacga tttaagaacc gtgacaatct aagattaacg gatttcgttg agataatttt
    74041 aaaaaatcct gaactaacca tcagacttcc tcttgcggtt tcaaataagc gagtttatcc
    74101 aagtctgaat ttggaagagg ctagagctct attgccaaga gatacgaaac aattgattta
    74161 catggcgcaa acacattatt tatctaacta aaggagaagc aatatggctg aacgattttg
    74221 ggagaacttg tccattattt tggctgaaag aaatatcagc tggattgagt taaccagaaa
    74281 aatgtttgcg ggagagtttc actatccaag tgaattgaat cgtttgtatc aaaagattcg
    74341 ccactagaag atggaacaat gaatgcctca aagtccatgg gtagaaagga ttgtgcaggt
    74401 attagattta gattatgaag atttatttcg gaggtaacta tgaaaagaat aattccagtt
    74461 tatatattcc aacaagtaaa tgtcctattg gtatctctat acttattgaa atttctttgt
    74521 atcggtgagt taactatact acagattctc tatggttcgt cactcatttc ttttttatgg
    74581 atgtatggcc aacgcaaaca agcgcataag gtcaatatga aatctaggat gaaatggctt
    74641 ggtgttgaat ttgttagcct actgattata agtctatgtt ttagtctgat tcatgctcaa
    74701 ggaagcacga atcaagcaaa cttaattggc cttcaacatc aaattccttg gttttcattt
    74761 ttattgttct taatcaatgc gagtatggtt gaagaatttc tgtatcgaga aattttatgg
    74821 aatttggtca gaaaattaga tatcagagtt gctttgacaa gtgttttatt tgccttagca
    74881 catcatacag gaaccattct agcttggtgt ttgtatgttt cacttgggat gtttttaggt
    74941 atggtgcgct ataaatctga cttatggggc agtatgggac tacatttggt gtggaaccta
    75001 ctagtttata gtttgctgct tttttaaaat aggtgacctg atttttaggt aacttctaaa
    75061 actaacttcc agttttggga gagagatgga agttactttg aaaagttacg gaaacattat
    75121 tttctatgtg acaacattgt ataattgctt gcattttact ggtggagaga gtataatgag
    75181 ggtggataaa gtacttaatc ccaaaaattt aaataggagg agctagctat ggcagaagaa
    75241 gtattaaatc ttcaattagt atctgttcaa gttgacgaaa cagatgaagt tgatggaatg
    75301 cgatttagta cattcagtac aaatcgttgc ggtaactgga gtgcttttag ttgggaaaat
    75361 tgttaattca tttaaattgt aaactttaga gattctctgg agttatggat gtcgttccaa
    75421 tatgtgcacg ttggaatgtt agtgcttata tggggagaat ccaaaggatt ctcccttttt
    75481 atttaaataa gtctgtctag ctatagatat attaagtttg ataaaatttc ttggagattt
    75541 tgttatggat tataatttca atttggagca tcctttcttt ttcactaata atgattatag
    75601 tacagatact agcataaagt accaagtaag tctgcctttt aattggcacg aagtaatgaa
    75661 taatgatgag tgggtttatc aataccctat tggaaaattt gttgaaagac aagggtggaa
    75721 aatacacatt agttcagagt ataacagttc acatgaattg ttacaagatg tagcaaaaat
    75781 ttgccatgaa atgcgaattc catttaaaca tcttagtaca gaagacaaat ttatcatgcg
    75841 aaacgggaaa ttggttagtc gaggattttc tggtaaattt attacatgtt atccaaatca
    75901 aaatgaatta gagtcggttt tgcaaaggtt agaaagtgcc ttaaagcaat ataatgggcc
    75961 atatatttta agcgataaac gttgggatga agcaccaata tatctgaggt atggtgtgtt
    76021 taggccgtca agggatgatg aaaagaaggt tgctattgat gaattaattg ttggcgatga
    76081 agttgttaaa gatgaacgtt taccagtatt taaaattcca aaaggtatag tgccccctga
    76141 ctttttgaat aaatggcttg acaagaaaga taaaaaacag ggagactttc cctttattat
    76201 agataatgca attagatttt caaacagtgg tgggatatat aatgctaggc taaaagaaga
    76261 tgggaaaaaa ataattttaa aagaggctag accgtataca ggtctaggat ttgatggtac
    76321 ttattcttca gagaaattag cttcggagtg caaagcacta aaaattctaa atgaatggag
    76381 tgagacgcct aaaatatact ggcacggtaa gatctgggag cacaccttct taggaattga
    76441 acatatgaag ggcgttccac taaatagatg ggttaccaat aattttcctt tatatgaagt
    76501 tgttgataag accaaagatt atctattgag agtttcaaag atagtagaaa aactcatcga
    76561 tttaacgaat aagtttcatt ctgaaattga gagggtttac gctaacttat ggacagtggc
    76621 gtaaagaatt tcaatcaaga ttcttcccag ttcattatta tggtctgaat tttaatcaag
    76681 gaattgcgtt ttcagattta gctatccttt ggagttatca acaactagct aagaaagtaa
    76741 aaaatttcaa gtttgatgac tattatgaga ttcgaacaca ggttattaat gaggcagtaa
    76801 ataattttaa gaaatcgtcc ctttctggtc tttttgatgg taaaattggt acaatctggc
    76861 tcatttatga atttggggag atagatcggg cagttgaact ttttacaact cattttatag
    76921 agatatttga gaattcacaa aataaaaatt tatatagtgg gcaggtaagt attgacttct
    76981 catttaagtc accatttagg gtattattaa caggaacttc tggcagtggg aaaacaacga
    77041 ttttaaattt aattaatggt tctttaaagc cacaaaaagg ttatgtaaat ttgttatcac
    77101 atgggaaaaa gagttcagat tcaataccaa cagttgatca gacaccatat atttttgaca
    77161 ctactattcg tgagaacgta actttatttc aaaatgaata tttttcagat gatcagataa
    77221 ttgaggtgtt aaaaaaggta aatctatatg aagaattaga aaagatagat atactaaatt
    77281 atcaatgtgg tgaaaatggt agtaatttgt ctggaggtca aaaacaaaaa atagctttag
    77341 ctagagctct gattagaaat aataaagtgt acttatttga cgaaatatca gctaatttag
    77401 ataatgataa ttcaaattcc atacatgata ttctgttcaa tttaggtatt tcatttattg
    77461 aagtttcaca tcattatgac ttaaatgaca agagatacac tgatatatat aaattggaaa
    77521 atggaacact tttcaaaatt aagtgattgg aggcaagaat atggataaag attatatatt
    77581 aaaagtgaaa gggctgtatc atcaattttt actaggaaat aataaaacgt tgcaagtgct
    77641 gaaaaatgtt tctctttctg cttcgagagg agaatttata agtattctag gaattagtgg
    77701 ttctggaaag tcaactttat taaaatgtat ttctagtttg cttgaaccaa caagtgggga
    77761 agtaatttta aatggaatca acccctataa aatcagaaat gcaaaattgt caagtataag
    77821 acgtaacgaa gtatctttta tatttcaagc atacaattta ataccttccc tgccggtaat
    77881 agaaaatata gcacttcctt tgcgattatc acaaaaaaaa ttaactatta aaaatgtaga
    77941 aaacttactc aaaagaatga agtttaatgc tggcttaaac gattttgttg gaactctgtc
    78001 tggtggagaa caacagaagg ttgctatagc tagagcggtt attgctgata gtgatataat
    78061 atttgctgat gagccaactg gggctttaga cagcgtttct cgtgaagtaa tttttgaatt
    78121 attgagagag ttagtagggg cgggtaagtg tgtaattatg gtaacgcacg atatagaatt
    78181 ggcctcgaaa actgatcgtg cattaatatt gaaagatgga aaaattttca aagaacttca
    78241 tagacctagc ggggaagagt tgtataaaat cttagaggta caatcaacta cggaggaata
    78301 gagatgctca gattagttta ctatcaattt ttacataata agaaacaatg gttaggcgtt
    78361 tcaccagtaa tttttgtttc gagtttagtt atgggattgg ctgttaatgg ggtaattaat
    78421 gttgagaata attcgcaagt atttgtcgga cttccagatc ctaaaccaat ttttatgttt
    78481 ccgatagtat tcggaggagt aacattattc tttgtgctct ctaacataat aaatatgttg
    78541 gttgaaattt ttagagatga ttacgaactt ttggaggtgt tgggagcaag tcgccttcaa
    78601 ctatcatttc ttgtgggggg acagattttt atcatttcct cgattattag ttttattgca
    78661 tatctatgct ctatatttgt tacgtcaaat tattattatt ttttacaata ctttttcggg
    78721 gaaaatatat tacctgatat ccaatttcaa acgagtgctg ttggatgtat cattacagta
    78781 gtgttgattt catttttagc ctttctaagt ggttgctttt atacgttcaa gaagattaga
    78841 aataggaaga gttctaaaat aaggcatgtt ctttcaatag taaaaagaat actgctattg
    78901 gctggtttta gtgttatctg gttgctttct ttgcaacaaa ttttccaaga tagcacaatt
    78961 ttagcgaagg cccagataat attcaatatt gtaatcttag atattgtgat tatttatcaa
    79021 ttatctcctt ttatacagtc atgtttt
//
LOCUS       DBJKQU010000005        66477 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.005, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000005 DBJKQU010000000
VERSION     DBJKQU010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 66477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66477
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.005"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..354
                     /locus_tag="ACSUUC_000362"
     CDS             <1..354
                     /locus_tag="ACSUUC_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HHQ8053656.1"
                     /translation="QVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQA
                     SMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNNKRIKVK
                     LKGLSPVQYRTKSFG"
     gene            complement(397..1038)
                     /gene="plsY"
                     /locus_tag="ACSUUC_000363"
     CDS             complement(397..1038)
                     /gene="plsY"
                     /locus_tag="ACSUUC_000363"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HHQ8053657.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1174..3117
                     /gene="parE"
                     /locus_tag="ACSUUC_000364"
     CDS             1174..3117
                     /gene="parE"
                     /locus_tag="ACSUUC_000364"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HHQ8053658.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3132..3336
                     /locus_tag="ACSUUC_000365"
                     /pseudo
     CDS             3132..3336
                     /locus_tag="ACSUUC_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            3537..6008
                     /gene="parC"
                     /locus_tag="ACSUUC_000366"
     CDS             3537..6008
                     /gene="parC"
                     /locus_tag="ACSUUC_000366"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HHQ8053659.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLV
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6140..7162
                     /locus_tag="ACSUUC_000367"
     CDS             6140..7162
                     /locus_tag="ACSUUC_000367"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HHQ8053660.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7218..7922
                     /locus_tag="ACSUUC_000368"
     CDS             7218..7922
                     /locus_tag="ACSUUC_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HHQ8053661.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            7987..8676
                     /locus_tag="ACSUUC_000369"
     CDS             7987..8676
                     /locus_tag="ACSUUC_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HHQ8053662.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8673..9596
                     /locus_tag="ACSUUC_000370"
     CDS             8673..9596
                     /locus_tag="ACSUUC_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HHQ8053663.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9611..10255
                     /gene="pcp"
                     /locus_tag="ACSUUC_000371"
     CDS             9611..10255
                     /gene="pcp"
                     /locus_tag="ACSUUC_000371"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HHQ8053664.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10423..10653
                     /locus_tag="ACSUUC_000372"
     CDS             10423..10653
                     /locus_tag="ACSUUC_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HHQ8053665.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10703..10783
                     /locus_tag="ACSUUC_000373"
     tRNA            10703..10783
                     /locus_tag="ACSUUC_000373"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10737..10739,aa:Tyr,seq:gta)
     gene            10793..10864
                     /locus_tag="ACSUUC_000374"
     tRNA            10793..10864
                     /locus_tag="ACSUUC_000374"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10825..10827,aa:Gln,seq:ttg)
     gene            11026..12228
                     /gene="rpsA"
                     /locus_tag="ACSUUC_000375"
     CDS             11026..12228
                     /gene="rpsA"
                     /locus_tag="ACSUUC_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HHQ8053666.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(12313..13639)
                     /locus_tag="ACSUUC_000376"
                     /pseudo
     CDS             complement(12313..13639)
                     /locus_tag="ACSUUC_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            13833..14330
                     /locus_tag="ACSUUC_000377"
     CDS             13833..14330
                     /locus_tag="ACSUUC_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HHQ8053667.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            14330..15985
                     /gene="dnaX"
                     /locus_tag="ACSUUC_000378"
     CDS             14330..15985
                     /gene="dnaX"
                     /locus_tag="ACSUUC_000378"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HHQ8053668.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            16013..16207
                     /locus_tag="ACSUUC_000379"
     CDS             16013..16207
                     /locus_tag="ACSUUC_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HHQ8053669.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            16357..17127
                     /gene="sufC"
                     /locus_tag="ACSUUC_000380"
     CDS             16357..17127
                     /gene="sufC"
                     /locus_tag="ACSUUC_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HHQ8053670.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            17155..18417
                     /gene="sufD"
                     /locus_tag="ACSUUC_000381"
     CDS             17155..18417
                     /gene="sufD"
                     /locus_tag="ACSUUC_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HHQ8053671.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKDAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            18428..19654
                     /locus_tag="ACSUUC_000382"
     CDS             18428..19654
                     /locus_tag="ACSUUC_000382"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HHQ8053672.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDRVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            19641..20081
                     /gene="sufU"
                     /locus_tag="ACSUUC_000383"
     CDS             19641..20081
                     /gene="sufU"
                     /locus_tag="ACSUUC_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HHQ8053673.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            20135..21547
                     /gene="sufB"
                     /locus_tag="ACSUUC_000384"
     CDS             20135..21547
                     /gene="sufB"
                     /locus_tag="ACSUUC_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HHQ8053674.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(21778..23019)
                     /gene="pbp3"
                     /locus_tag="ACSUUC_000385"
     CDS             complement(21778..23019)
                     /gene="pbp3"
                     /locus_tag="ACSUUC_000385"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HHQ8053675.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIEQI
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            23122..24231
                     /gene="cozE"
                     /locus_tag="ACSUUC_000386"
     CDS             23122..24231
                     /gene="cozE"
                     /locus_tag="ACSUUC_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HHQ8053676.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGVFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            24877..25224
                     /gene="ssrA"
                     /locus_tag="ACSUUC_000387"
     tmRNA           24877..25224
                     /gene="ssrA"
                     /locus_tag="ACSUUC_000387"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(25394..25481)
                     /locus_tag="ACSUUC_000388"
     tRNA            complement(25394..25481)
                     /locus_tag="ACSUUC_000388"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(25445..25447),aa:Ser,seq:gga)
     gene            25643..26383
                     /locus_tag="ACSUUC_000389"
     CDS             25643..26383
                     /locus_tag="ACSUUC_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHQ8053677.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            26380..27291
                     /gene="pfkB"
                     /locus_tag="ACSUUC_000390"
     CDS             26380..27291
                     /gene="pfkB"
                     /locus_tag="ACSUUC_000390"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HHQ8053678.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSDGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            27288..29240
                     /locus_tag="ACSUUC_000391"
     CDS             27288..29240
                     /locus_tag="ACSUUC_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HHQ8053679.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            29377..31629
                     /locus_tag="ACSUUC_000392"
     CDS             29377..31629
                     /locus_tag="ACSUUC_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HHQ8053680.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAVFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKEIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(31673..32107)
                     /locus_tag="ACSUUC_000393"
     CDS             complement(31673..32107)
                     /locus_tag="ACSUUC_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HHQ8053681.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
     gene            32270..34354
                     /locus_tag="ACSUUC_000394"
     CDS             32270..34354
                     /locus_tag="ACSUUC_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHQ8053682.1"
                     /translation="MFEIRNLSLSFAGRRLLEPTDLIFERGKVYTIYGKSGVGKSSLL
                     NKIGLLSATDPSVSYFFDGKEIDIENKKSVSVFIAEEVAFVFQGRNLINDLTVFENLR
                     LALNFYDLSPDEIESKIDTVLADLQISSLKHAYPEDLSGGEEQRVAIARALVTGKTLI
                     LADEPTSSLDKENREKISALLIDLAHKYHKIVLIVSHDEAMIAIGDVQLHFKDHKLVG
                     NCLILNSDEGIKDSKKWSSCLSSSHTKLSVLKHRRPFLPRLLAFFISLVVAIAVTSIN
                     FQSLFADKYHQLVNNSLENGFLVINDSLHLQTTKVLDDFLSFDKEEITSISTSQNIQT
                     VNPYIEFLSLGMTFDNSKDYSQLQKNFQPTLTIDGQTRSLTRNFSIQPLYQTNTTQRQ
                     IEYFDRSNEKGIYLSEQFISDEKLPNIVSGTTVTLTFYIPISLYESSIEKEGNILKGD
                     GGLFVKVDKTYPVLGIVKKSYPFEYSPYGNTLFMNIAEMEELQNEAIQQHPMTKMALD
                     GFPLKSWMPSAIHVLLKDSGAIPEELSRIRAISSQITILSSYENYEEFNKGLTYIRQF
                     LMLLSLVLLILVIAVLSFVFFLLNRPRRFEVGILKSLGYSTQNIVWLFLKELIGYGKT
                     ISILASCLLVILSILAMQVLKLEISDVFKFYLTSVFTLIGLSVSVLIISGLLPIYTTC
                     RQTVVDTIRKNG"
     gene            34364..34741
                     /locus_tag="ACSUUC_000395"
     CDS             34364..34741
                     /locus_tag="ACSUUC_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053683.1"
                     /translation="MKHKIMKKIIVVVFAIPWLTFLSQVHADYVSKSSSLDGYSLVGL
                     NVLNVTFNASGYSDTYSGSVSNMYFTDWAWFPNTISNRSTWKSSIPYGQRANGTVHIG
                     VGVNSPWGAVNLWGGQNYFSLDF"
     gene            34901..36043
                     /locus_tag="ACSUUC_000396"
     CDS             34901..36043
                     /locus_tag="ACSUUC_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HHQ8053684.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEVLEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            36052..37266
                     /gene="thiI"
                     /locus_tag="ACSUUC_000397"
     CDS             36052..37266
                     /gene="thiI"
                     /locus_tag="ACSUUC_000397"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HHQ8053685.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            37401..38214
                     /locus_tag="ACSUUC_000398"
                     /pseudo
     CDS             37401..38214
                     /locus_tag="ACSUUC_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            38236..38975
                     /locus_tag="ACSUUC_000399"
                     /pseudo
     CDS             38236..38975
                     /locus_tag="ACSUUC_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            38988..40154
                     /locus_tag="ACSUUC_000400"
     CDS             38988..40154
                     /locus_tag="ACSUUC_000400"
                     /EC_number="6.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HHQ8053686.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(40645..42315)
                     /locus_tag="ACSUUC_000401"
     CDS             complement(40645..42315)
                     /locus_tag="ACSUUC_000401"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HHQ8053687.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVDAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWGKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            42545..43234
                     /gene="coaB"
                     /locus_tag="ACSUUC_000402"
     CDS             42545..43234
                     /gene="coaB"
                     /locus_tag="ACSUUC_000402"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HHQ8053688.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            43246..43797
                     /gene="coaC"
                     /locus_tag="ACSUUC_000403"
     CDS             43246..43797
                     /gene="coaC"
                     /locus_tag="ACSUUC_000403"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HHQ8053689.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            43781..44344
                     /locus_tag="ACSUUC_000404"
     CDS             43781..44344
                     /locus_tag="ACSUUC_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHQ8053690.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGITLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            44626..45153
                     /locus_tag="ACSUUC_000405"
     CDS             44626..45153
                     /locus_tag="ACSUUC_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHQ8053691.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            45165..45680
                     /locus_tag="ACSUUC_000406"
     CDS             45165..45680
                     /locus_tag="ACSUUC_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HHQ8053692.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(45677..46144)
                     /locus_tag="ACSUUC_000407"
     CDS             complement(45677..46144)
                     /locus_tag="ACSUUC_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HHQ8053693.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(46217..46705)
                     /locus_tag="ACSUUC_000408"
     CDS             complement(46217..46705)
                     /locus_tag="ACSUUC_000408"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8053694.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            complement(46671..47234)
                     /locus_tag="ACSUUC_000409"
     CDS             complement(46671..47234)
                     /locus_tag="ACSUUC_000409"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8053695.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            complement(47244..49232)
                     /gene="uvrB"
                     /locus_tag="ACSUUC_000410"
     CDS             complement(47244..49232)
                     /gene="uvrB"
                     /locus_tag="ACSUUC_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HHQ8053696.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(49309..50262)
                     /locus_tag="ACSUUC_000411"
     CDS             complement(49309..50262)
                     /locus_tag="ACSUUC_000411"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHQ8053697.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAIVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            50432..52597
                     /locus_tag="ACSUUC_000412"
     CDS             50432..52597
                     /locus_tag="ACSUUC_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HHQ8053698.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            52597..53337
                     /locus_tag="ACSUUC_000413"
     CDS             52597..53337
                     /locus_tag="ACSUUC_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053699.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            53486..54973
                     /gene="zwf"
                     /locus_tag="ACSUUC_000414"
     CDS             53486..54973
                     /gene="zwf"
                     /locus_tag="ACSUUC_000414"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HHQ8053700.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(55019..56296)
                     /gene="ftsY"
                     /locus_tag="ACSUUC_000415"
     CDS             complement(55019..56296)
                     /gene="ftsY"
                     /locus_tag="ACSUUC_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HHQ8053701.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(56300..57118)
                     /locus_tag="ACSUUC_000416"
     CDS             complement(56300..57118)
                     /locus_tag="ACSUUC_000416"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHQ8053702.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            complement(57118..57912)
                     /locus_tag="ACSUUC_000417"
     CDS             complement(57118..57912)
                     /locus_tag="ACSUUC_000417"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHQ8053703.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            complement(57909..61448)
                     /gene="smc"
                     /locus_tag="ACSUUC_000418"
     CDS             complement(57909..61448)
                     /gene="smc"
                     /locus_tag="ACSUUC_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HHQ8053704.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRVGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVYNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            complement(61439..62137)
                     /gene="rnc"
                     /locus_tag="ACSUUC_000419"
     CDS             complement(61439..62137)
                     /gene="rnc"
                     /locus_tag="ACSUUC_000419"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HHQ8053705.1"
                     /translation="MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            complement(62320..62391)
                     /locus_tag="ACSUUC_000420"
     tRNA            complement(62320..62391)
                     /locus_tag="ACSUUC_000420"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(62356..62358),aa:Arg,seq:ccg)
     gene            complement(62455..63441)
                     /locus_tag="ACSUUC_000421"
     CDS             complement(62455..63441)
                     /locus_tag="ACSUUC_000421"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HHQ8053706.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            complement(63616..64932)
                     /locus_tag="ACSUUC_000422"
     CDS             complement(63616..64932)
                     /locus_tag="ACSUUC_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HHQ8053707.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IVVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            complement(64919..>66477)
                     /locus_tag="ACSUUC_000423"
     CDS             complement(64919..>66477)
                     /locus_tag="ACSUUC_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HHQ8053708.1"
                     /translation="YEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTKLLCIYTEGD
                     PFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKLGTMLFEYSK
                     LFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEIAKELTDGNE
                     DQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKETQLIGGQDN
                     FDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLPSKYVYELYK
                     DKNYNKQEYYKSGGKTVLETLRKRFGLKDYISPEEVETDKKFVFIIDEINRGEISKIF
                     GELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDRSVDTFDFAM
                     RRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSHYHIGPSYFL
                     KLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQKDQAVADDN
                     EGDENDDADY"
BASE COUNT        19755 a        13118 c        13591 g        20013 t
ORIGIN      
        1 caagtacaaa caatgttgga acaggcattc acagagaagc actacgagaa tacgattctc
       61 catagtgacc aaggctggca atatcaacac gattcttatc atcagtttct tgagggtaag
      121 ggaattcaag catccatgtc acgtaagggt aacagcccag acaatggtat gatggagtcc
      181 ttctttggga ttctgaaatc ggaaatgttt tacggttatg agaagtcgtt tcagtcgctt
      241 aagcaattgg aacaagccat tgtagactat attgattact acaacaataa acgaattaag
      301 gtaaaactaa aaggacttag ccctgtgcaa tacagaacta aatccttcgg ataaattaat
      361 tgtctaactt tttggggtca gtacagaact ggcgttttat tttttaggat cttgatgggt
      421 taggttcaat ccccaaggga ccaaattttc agttttattt ttgatacgag ctatattgtc
      481 cttatgacga atgataatca aactagcaag tgctaagata atagcgatga agagagagtc
      541 atagttactc aggataaaac caaaaagtgg aaagagcaga accccgataa cagccgcgat
      601 cgatgctgtg acactagaca gtgaaatcat actgccaaga tagagagctc caaagaagat
      661 aatcgcaagg tagagacaga agataggcgc aaatccgaaa atcactccag cactggttgc
      721 gacagcctta ccacctttaa atcctgcaaa tatagggaag gtatggccga taacagccaa
      781 aagtccaaag atgagaggag aaacgccttg tagatgaaaa ataatcggaa gcagcgttgc
      841 tagggttcct ttgaaaaagt caatcacaaa ggttgccata ccagctttct tacctaaaat
      901 gcggaaggtg ttggtcgttc cagtgttacc agaaccatgc tcgcgtagat tgatttgaaa
      961 gaatacttgt ccaatccaga gaccagatgg aatcgaaccc agcagatagg ctaggattaa
     1021 taaaactatt gtaatcatac tcctattata tcatgaattg ggaaagaaaa gcagagaatc
     1081 tctgctgaaa ttgtcacatc ggagaaagaa aaattttgca aaatccttgg aaaacctgta
     1141 gaatagtaaa gatgaacgaa taggaggttc cttgtgtcaa aaaaggaaat caatattaac
     1201 aattataatg atgatgctat tcaggtgcta gaagggttgg atgcggtccg aaaacgtcca
     1261 gggatgtata ttggatcgac cgatggcgct ggtcttcatc acctagtttg ggaaatcgtt
     1321 gataatgcag tcgatgaagc cttgtctggg tttggtgatc gtattgatgt aactatcaat
     1381 aaagacggta gtctaacggt tcaagaccat ggacgtggga tgccgacagg tatgcacgct
     1441 atgggaattc caactgttga ggttatcttt accattcttc atgccggagg gaaattcggt
     1501 caaggtggct ataagacatc aggtggactt cacggagtgg gttcttccgt tgttaacgcc
     1561 ctttctagct ggttagaagt tgaaattacc cgtgatggcg cagtttacaa gcaacgtttt
     1621 gaaaatggtg gaaaacctgt cacgactttg aagaaaatcg gtacagcacc caagtctaaa
     1681 acaggcacca aagttacttt tatgcctgac gcgactatct tttctacgac agatttcaag
     1741 tacaatacca tttcagagcg ccttaatgaa tcagcctttc tcttgaaaaa tgtgaccttg
     1801 tctttaacgg acaagcgaac agatgaagcg attgagttcc actatgagaa tggagtacaa
     1861 gattttgttt cttatctcaa cgaagataag gaaatcttga cgccagttct ttactttgaa
     1921 ggggaagaca atggttttca agtggaagta gccctccagt acaatgacgg attctcagat
     1981 aacattctat cctttgtcaa taacgttcgc accaaggacg gtggaacgca cgagacagga
     2041 ctcaagtctg ccattaccaa ggtcatgaat gactatgcac gtaaaacagg tcttctcaag
     2101 gaaaaagata aaaaccttga aggttcagac tatcgtgagg gactagcggc cgttctttct
     2161 atcttagttc ctgaagaaca cttgcagttt gaaggacaga ccaaggataa actaggaagc
     2221 cccctagctc gcccagttgt ggatggaata gtggctgata agttgacctt tttccttatg
     2281 gaaaatgggg aattagcttc taacctcatc cgcaaggcta tcaaggcccg tgatgctcgt
     2341 gaagcagcac gtaaggcgcg tgatgagagc cgaaatggga agaaaaacaa gaaagataag
     2401 ggcttgttgt ctgggaaatt gaccccagcc caatctaaga atcctgctaa gaatgaactc
     2461 tatctagttg agggggactc tgccggtggt tctgccaaac aaggtcgtga ccgcaagttc
     2521 caggctattc tacctcttcg tggtaaggtt gtcaatacag ccaaggccaa gatggcggat
     2581 atcctcaaaa atgaagagat caataccatg atttatacca ttggtgcggg tgttggagca
     2641 gacttctcta ttgaagatgc caactatgat aagatcatta tcatgaccga tgcggatacc
     2701 gacggtgccc atatccagac cttgctcttg acatttttct accgttacat gcgtccgcta
     2761 gtcgaggcag gtcatgtcta tattgccctc ccacctcttt acaagatgtc caaaggtaaa
     2821 ggcaagaaag aagaagtggc ctacgcttgg acggacggag aactagaaga actccgtaaa
     2881 cagttcggta aaggcgctac cctccaacga tacaaaggac ttggtgagat gaatgcggac
     2941 cagctctggg aaacaaccat gaacccagaa acacgtaccc tcatccgtgt cacaattgaa
     3001 gatttagcgc gcgccgaacg ccgcgtcaat gttctcatgg gagataaggt agaaccacgc
     3061 cgtaaatgga ttgaagataa tgtcaagttt acgctagaag aagcgacagt gttttaatga
     3121 aagaaaataa tatgttagta aactggaaat tagagtcgga tgtgaatgac tatgtgaaaa
     3181 agcagtttga aaatcttggt ttgaaaaaat tgcaggatta ttaatgaaga atctgctatg
     3241 agtgcttatc tcaaagaggc gtttaaggga gcggctaaga cacaaactaa gactaatttt
     3301 ggaaaaccat attttcatat tgaaaaatac aaacaggata gtttggttac ttatcgtaac
     3361 tgaacacggg acgaattccc gtaaaatatc ttttactgca taaaaaccta ctctacattc
     3421 tttgaaagga gttgaacacg ccctagatac tgtgtgaaaa agataaattc tcttgtgagt
     3481 ttgcttactt caagaatttt ctattttcac ttggtatttt atgggctttg tatcttatgt
     3541 ctaacattca aaacatgtcc ctggaggaca tcatgggaga gcgctttggt cgctactcca
     3601 agtacattat tcaagaccgg gctttgccag atattcgtga tgggttgaag ccggttcagc
     3661 gccgtattct ttattctatg aataaggata gcaatacttt tgacaagagc taccgtaagt
     3721 cggccaagtc agtcgggaac atcatgggga atttccaccc acacggggat tcttctatct
     3781 atgacgccat ggttcgtatg tcacagaact ggaaaaatcg tgagattcta gttgaaatgc
     3841 acggtaataa cggttctatg gacggagatc ctcctgcggc tatgcgttat actgaggcac
     3901 gtttgtctga aattgcaggc taccttcttc aggatatcga gaaaaagaca gttccttttg
     3961 catggaactt tgacgatacg gagaaagaac caacggtctt gccagcagcc tttccaaacc
     4021 tcttggtcaa tggttcgact gggatttcgg ctggttatgc cacagacatt cctccccata
     4081 atttagctga ggtcatagat gctgcagttt acatgattga ccacccaact gcaaagattg
     4141 ataaactcat ggaattcttg cctggaccag acttccctac aggggctatt attcagggtc
     4201 gtgatgaaat caagaaagct tatgagactg ggaaagggcg cgtggttgtt cgttccaaga
     4261 ctgaaattga aaagctaaaa ggtggtaagg aacaaatcgt tattactgag attccttatg
     4321 aaatcaataa ggccaatcta gtcaagaaaa tcgatgatgt tcgtgttaat aacaaggtag
     4381 ctgggattgc tgaggttcgt gatgagtctg accgtgatgg tcttcgtatc gctatcgaac
     4441 ttaagaaaga cgctaatact gagcttgttc tcaactactt atttaagtac accgacctac
     4501 aaatcaacta caactttaat atggtggcga ttgacaattt cacacctcgt caggttggga
     4561 ttgttccaat cctgtctagc tacatcgctc accgtcgaga agtgattttg gcgcgttcac
     4621 gctttgacaa agaaaaggct gagaaacgtc tccatatcgt cgaaggtttg attcgtgtga
     4681 tttcgatttt ggatgaagtc attgctctta tccgtgcttc tgagaataag gcggacgcca
     4741 aggaaaacct caaagttagc tatgatttta cggaagaaca ggctgaggct atcgtaactt
     4801 tgcaactgta ccgtttgacc aataccgatg tggttgtctt gcaggaagaa gaagcagagc
     4861 ttcgtgagaa gattgctatg ctggtggcta ttatcggtga tgaaaggact atgtacaatc
     4921 tcatgaagaa agaacttcgt gaggtcaaga agaaatttgc aactcctcgt ttgagttctt
     4981 tagaagacac tgcgaaagca attgagattg atacagctag tcttatcgct gaggaagata
     5041 cctacgtcag cgtgaccaag gcaggttaca tcaagcgtac cagtccacgt tcctttgcgg
     5101 cttccacctt ggaagaaatt ggcaagcgtg atgatgaccg tttgattttt gttcaatctg
     5161 ccaagacaac ccagcacctc ttgatgttca caagtcttgg aaatgtcatc tacagaccaa
     5221 tccatgagtt ggcagatatt cgttggaagg acatcggaga gcatctgagc caaaccatca
     5281 caaactttga aacgaatgaa gcaatccttt atgtggaagt actggatcag tttgacgatg
     5341 cgacaaccta ctttgcagcg actcgccttg gtcaaatcaa acgggtagag cgaaaagaat
     5401 tcactccatg gcggacctat agatctaagt ctgtcaagta tgctaagctc aaagacgata
     5461 cagatcagat tgtagcagtg gctccgatta aactagatga tgttgtcttg gttagtcaaa
     5521 atggttatgc cctgcgtttc aatatcgaag aggttccggt tgtcggtgct aaggcagcag
     5581 gtgtcaaggc tatgaatttg aaagaagatg atgtcctcca atctggcttt atctgtaata
     5641 cttcgtcctt ctacctcttg acccagcgtg gaagcttgaa acgtgtttcc attgaggaaa
     5701 ttctagcaac cagccgtgcc aaacgaggat tacaagtctt gcgtgagttg aaaaacaaac
     5761 cgcatcgtgt cttcttggca ggagcagttg cagagcaagg atttgttggc gatttcttca
     5821 gtacggaagt ggatgtgaac gaccaaactc tgcttgtcca atccaataaa ggaacaatct
     5881 atgaaagccg attgcaagac ttgaacttgt cagaacgcac tagcaatgga agcttcattt
     5941 ctgacacgat ttcagatgaa gaagtttttg acgcttatct tcaggaagta gttactgaag
     6001 ataaataagt gaaatgaaga atcagttcta agagctggtt tttattggag aaattttctg
     6061 aaaattacaa aatatacttg ctattttaga aaaatagtgt agaatataag aaataggttt
     6121 ttagaataag gagtggaata tgacagtaac gattgattgg gaaaacctcg gtttttccta
     6181 tatgaaatta ccttatcgct atcttgctca tttcaaaaat ggacaatggg atcaaggaga
     6241 gcttacagag gatgcaactt tgcatatttc agagtcttct ccaagtcttc actatggaca
     6301 acaagcattt gaaggtttga aagcttatcg tactaaggat ggcagtgttc aactgttccg
     6361 tcctgatgaa aatgctaaac gcctgcaacg tacatgtgac cgtctcttga tgccacaagt
     6421 tccgacagac atgtttgtag aagcttgtaa agcagttgtc cgtgcgaatg aagaatacgt
     6481 accaccatac ggaataggtg gaaccttata tcttcgccct cttttgattg gtgtcggaga
     6541 tattatcggg gtaaaaccgg cagaagaata cattttcacc atctttgcta tgccagttgg
     6601 aaattacttt aaaggtggtt tggtcccaac caacttcttg attcaggatg agtacgaccg
     6661 tgcagcacca aatggtacag gtgcggctaa ggttggtgga aactatgctg caagtctctt
     6721 accaggaaaa atggccaagt cacgtcattt ctcagatgtt atctatctgg acccatcaac
     6781 tcatacaaag attgaagaag tcggatcagc taacttcttt ggaattacag ctgataatga
     6841 atttgtaaca ccattgagtc catctatctt gccatctatt accaagtatt ccttgcttta
     6901 tttggcagaa catcgcttgg gattaactcc tattgagggt gatgttccaa ttgataatct
     6961 tgaccgtttt gtagaggcag gtgcctgtgg tacagcagcg gttatttctc caattggagg
     7021 tattcaacat ggtgatgatt tccatgtatt ctatagtgaa acagaagtag gtcctgtgac
     7081 gcgtaaatta tataatgaat tgacgggtat tcagtttggc gatattgaag cgccagaagg
     7141 ttggattgta aaagtagatt aaaataaacc aaaggagatt ttttatgaaa tagaaaaagc
     7201 ggctcttaac agcaggagtg gtcctgagca cgtcagctat tttagtggct tgtggaaaaa
     7261 ctgataaaga agcagatgca ccgacaacat tttcttatgt ctatgcagta gatccagcat
     7321 cattgggcta cagtatagcg actcgaacat cgacgacaga cgttattgga aatgttattg
     7381 atggtttgat ggaaaatgat aaatacggca atgttgctcc ttctcaaaaa gactatgatt
     7441 tgaatagtac aggatgggct ccaagctatc aagatccagc gtcttacttg aatattatgg
     7501 atccaaaatc tggttctgcc atgaaacacc ttggcattac gaaaggaaaa gataaggatg
     7561 ttgtagctaa acctggtttg gataaatata agaaattgtt agaagatgct gtttctgaga
     7621 ccactgacct agagaagaga tatgaaaaat atgccaaagc tcaagcttgg tcgacagata
     7681 gttcattatt gatgccaaca gcttcatctg gtggttctcc agttgtaagt aacgtagtac
     7741 cattctcaaa accatactca caagttggta ttaaggggga accatatatc tttaaaggaa
     7801 tgaaattgca aaaagatatt gttacaacaa aagaatataa cgaggttttt aaaaaatggc
     7861 aaaaagaaaa attggaatcc aatagcaaat accaaaaaga actagaaaaa tacattaaat
     7921 aaggaatggt attgatcttg ataaaatttt taaaatactg tcattttgaa tataaaggag
     7981 tttgatatgg agtggattag attaatagga atagcaatca ttgttgtggg ttttatttta
     8041 aaatttgata caattgcaac agtagtctta gctggtttgg ttacagcttt agtttcaggt
     8101 gtttctctcg ttgaattttt ggagattttg ggaaaagaat ttagcaatca gcgagtgctc
     8161 acgattttta tggttacctt gcctcttgtg gggctgtcag aaacctttgg actcaagcaa
     8221 cgatcaatcg atttgattcg aaagattaaa ggtctgacag ttggaaactt ctatacagtt
     8281 tatttcttta ttcgagagtt agctggtttc ttttcaattc gtctaggagg acaccctcag
     8341 tttgtcagac ctttggttca acctatggga gaagcagctg cagagtctca attaggtaga
     8401 aagttaacag aggttgaaga tgagacaata aaagcgcgtg cggctgcgaa tgaaaatttt
     8461 ggaaatttct ttgctcaaaa tacgtttgta ggtgctgggg gagtcctctt gataggggga
     8521 acattagatc agttaggcta tgaaagcaat tatgcaggga ttgcttctac atctattatt
     8581 gttgctgtta taacacttat tgtagtgggg atttacaatt atttatttga taaaaaattg
     8641 atatcaaaaa agactagggg aggagaacaa aaatgacaga gttggcaaag caactattag
     8701 agttgaccta tattgtgatt ggttgtcaat ttctccatac agcctattgt agttataaag
     8761 ataaaacaaa cccagttcga cttgggacat ctgcattttg gactctattg tctattacgt
     8821 ttataggtgg ttcctatatg ccaaatatga gtattggtat tattgtaatc ctattatcgc
     8881 tgttaacatt gtttaagcaa gtccgtatcg gaaccttgcc atccttagat gaaatgaaag
     8941 ccaatattga atctaacagg ttgaaaaata aaatttttat tccagttatg ctgatggcaa
     9001 tacttgcgtt ggtcttagcg caaatgattc cagaatttag caagatttcg attagccttg
     9061 ccgccttgtt tgctacaatt tctgttcttg tgattaccaa tagtcaccct aagagtctgt
     9121 tatcagaaaa taatcgaatg actcagcaag tttcaacaag tgggattgtt cctcaattat
     9181 taggggcttt gggggctatt tttactgtag caggtgttgg tgatgttatc tctcatctga
     9241 ttagcggtat tgttccttca gatagtcgct ttataggagt tttggcttat gttcttggaa
     9301 tggttctatt cacaatgatt atgggaaatg cttttgcagc attcaccgtt attacagcag
     9361 gtgttggagt tccctttgta tttgctctgg gagctaatcc aattgtggct ggtgctcttg
     9421 ccatgacagc aggttattgt gggaccttat tgaccccaat ggctgctaat tttaacgctc
     9481 taccagcagc attgatggat atgaaagatc agaatggcgt tataaaggct caagcaggtg
     9541 ttgctctagt aatgattgtt attcacatat tcttaatgta ctttctcgca ttttagtaaa
     9601 ggaaaataaa atgaaaatat tggttacagg ttttaatcct tttggaggtg aaaagattaa
     9661 tccagctttg gaggctgtaa aattattacc atctgagatt aatggggctg aagttcgctg
     9721 ggtagaaatt ccaacggttt tttataagtc gtcagaagtt ttagaggcag aaatattacg
     9781 atatcaacca gatgctgtac tttgtattgg acaagcaggc ggcaggaccg gcttaacacc
     9841 tgaacgagtg gctattaatc aagatgatgc tcgcatacct gataacgaag gcaatcaacc
     9901 aattgataca ccgattcgta ttgatggagc atcggcctat tttagtagtt tacctatcaa
     9961 agcgatggta caagctatca aaaaacaggg acttccggca gttgtatcca atagtgcagg
    10021 aacctttgtt tgcaatcatt tgatgtacca agctctttat ttagtggata aaaaattccc
    10081 taatatgaga gcaggtttca tgcatattcc atatatgatg gaacaagtag taaataagcc
    10141 gaatactgca ggaatgagtc tatgtgatat tgtaagaggc atagaggtag ctattgaagc
    10201 tattgtagac tacaaagata aggatttgca gttagtaggc ggtgagactc actgataacc
    10261 taaaaaggat agtcaattat gcttgtttac taactattaa ctatgctaaa tcaattgagg
    10321 ttgtttacat aaaactctat atcagagaag cctgatatag agttttttct tgctagtttt
    10381 aggattttct tgtaaaatag aaaaagtgaa gagaggtatg aaatgagcaa gaaagataaa
    10441 aaaatcgaaa ttcaagtagc ggatgccaaa gttaatgttg gtaaagacag ttttgaaggt
    10501 tatacattga ctatcggtaa aaaagttatc ggagaaattg ccgaattaga cggacaattt
    10561 gccattataa agaatgggaa tgtcgatagt ttttataaaa aattggaaaa agctgtggaa
    10621 attttgattg aaaattataa tttagcaaaa taagtcttgt ttttttgaaa ttttcatgat
    10681 ataatagtcc atgttgattg taggagagat agcgaagagg ctaaacgcgg cggactgtaa
    10741 atccgctcct tcgggttcgg gggttcgaat ccctctctct ccatttcatt aatggggtat
    10801 agccaagcgg taaggcaagg gactttgact ccctcatgcg ttggttcgaa tccagctacc
    10861 ccagttctta ggtaataatc aagatagaaa gcaaaatatc ttagggtatt ttatttttat
    10921 aattgaaaga cgtgaatgat atgaacatgt ccttgcgggt gcttaggaaa aaaattataa
    10981 gtatgtcaag tttaagaaaa acttgattgt tggaggattt tttagatgaa cgaatttgaa
    11041 gatttgctaa atagcgttag tcaagttgag actggtgatg ttgttagtgc tgaagtattg
    11101 acagttgatg cgactcaagc taacgttgca atctctggaa ctggtgttga aggtgtcttg
    11161 actcttcgcg aattgacaaa cgatcgtgat gcagatatca atgactttgt taaagtagga
    11221 gaagtattgg atgttcttgt acttcgtcaa gtagttggta aagatactga tacagttaca
    11281 taccttgtat ctaaaaaacg ccttgaagct cgcaaagcat gggacaaact tgttggtcgc
    11341 gaagaagaag ttgttactgt taaaggaacg cgtgccgtta aaggtggact ttcagtagaa
    11401 tttgaaggtg ttcgtggatt tatcccagct tcaatgttgg atactcgttt cgtacgtaac
    11461 gctgagcgtt ttgtaggtca agaatttgat actaaaatca aagaagttaa cgctaaagaa
    11521 aaccgcttca tcctttcacg tcgtgaagtt gttgaagcag ctactgcagc agctcgcgct
    11581 gaagtattcg gtaaattggc tgttggtgat gttgtaactg gtaaagttgc tcgtatcaca
    11641 agcttcggcg ctttcatcga ccttggtggt gttgacggat tggttcactt gactgaattg
    11701 tcacatgaac gtaacgtatc accaaaatca gttgtaactg ttggtgaaga aattgaagtg
    11761 aaaatccttg atcttaacga agaagaagga cgtgtatcac tttcacttaa agcaacagta
    11821 ccaggaccat gggatggcgt tgagcaaaaa ttggctaaag gtgatgtagt agaaggaaca
    11881 gttaaacgtt tgactgactt cggtgcattt gttgaagtat tgccaggtat cgatggactt
    11941 gttcacgtat cacaaatttc acacaaacgg attgaaaatc caaaagaagc tcttaaagtt
    12001 ggtcaagaag ttcaagttaa agttcttgaa gttaacgcag atgcagaacg cgtgtcactt
    12061 tctattaaag ctcttgaaga acgtccagcc caagaagaag gacaaaaaga agaaaaacgt
    12121 gctgctcgtc cacgtcgtcc aagacgtcaa gaaaagcgtg atttcgaact tccagaaaca
    12181 caaacaggat tttcaatggc tgatttgttt ggtgatatcg aactttaatc aaattgaaaa
    12241 ttcacaaaat cctttgttta ctaaacaagg gatttttctg gctctttgtc aactgtagtg
    12301 ggttgaagtc agctaagctt gagaaaggac aaatttcgtc ctttcttttt tgatgttcaa
    12361 agcgataaaa atccgttttt tgaagttttc aaagtttcga aaaccaaagg cattgcgctt
    12421 gataagtttg atgagattat tggtcgcttc cagtttggca ttagaatagt gtagttgaag
    12481 ggcgttgata atcttttctt tatctttgag gaaggtttta aagacagtct gaaaaatagg
    12541 atgagactgc ttaagattgt cctcaataag tccgaaaaat ttctctggtt ccttattctg
    12601 gaagtgaaac agcaagagct gatagagctg atagtggtgt ttcaagtctt gtgaatagct
    12661 caaaagcttg tctaaaatct ctttattggt taaatgcata cgaaaagtag gacgataaaa
    12721 tcgcttatca ctcagtttac ggctatcctg ttgtatgagc ttccagtagc gcttgatagc
    12781 cttgtattca tgggattttc gatgaaactg attcatgttt tgaacacgca cacgactcat
    12841 agcacggcta agatgttgca caatgtgaaa gcgatcaaga acgattttag cattcgggag
    12901 tgaaacagtc tgggagactg tttcagcctg agcctagaaa tttgaaagcg aagctgttta
    12961 gccaagtcat agtaagggct aaacatatcc atagtaataa ttttgacgcg acatcggaca
    13021 gctctatcgt agcgaagaaa gtgatttcga atgatagctt gtgttcttcc ctcaagaaca
    13081 gtgatgatat tgagattgtt aaaatcttgc gcaatgaagc tcatctccat ctcccgattg
    13141 aaacagtcac tccccggact gtttcaacgt cccaggacat aatctcagga agacgcgaaa
    13201 aatcatgctc aaagtgagaa tcattgagct tgcgaatgac agttgaagtt gagatggaaa
    13261 gctgatgggc aatatcagtc atagaaatct tttcaattaa cttttgagca attttttggt
    13321 tgatgatacg agggatttgg tgatttttct ttaccagggg agtctcagca accatcattt
    13381 ttgaacagtg atagcacttg aaacggcgtt ttctaaggag aattctagaa ggcataccag
    13441 tcgtttcaag ataaggaatt ttagaaggtt tttgaaagtc atatttcttc atttgacttc
    13501 cgcactcagg acaagatgga gcttcatagt ccagtttggc gatgatttcc ttgtgtgtat
    13561 ccttattgat gatgtctaaa atctggatat tagggtcttt aatgtctagt aattttgtga
    13621 taaaatgtaa ttgttccata tgaatctttc taatgagttg tttgatcgct tttcattata
    13681 ggtcatatgg gacttttttt ctacacaaaa ataggctcca taatatccat aggggattta
    13741 cccactacaa atattataga gcccaaaatc ctttgtttac taaacaaggg atttttcttt
    13801 tgtctctgct ccttttttga tataatagtt ctatgttaaa atcagaaaaa caatcacgtt
    13861 atcaaatgtt aaatgaagaa ttgtccttcc tattggaagg cgaaaccaat gttttggcta
    13921 atctttccaa cgccagtgct ctcataaaat cacgttttcc taataccgta tttgcaggct
    13981 tttatttgtt cgatggaaag gaattggttt taggcccctt ccaaggaggt gtttcctgca
    14041 tccgtattgc actaggcaag ggtgtttgtg gtgaggcagc tcactttcag gaaactgtta
    14101 ttgttggaga tgtgacgacc tatctcaact atatttcttg tgatagtcta gctaaaagtg
    14161 aaattgtggt gccgatgatg aagaatggtc agttacttgg agttctggat ctggattctt
    14221 cagagattga ggattacgat gctatggatc gagattattt ggaacaattt gtcgctattt
    14281 tgcttgaaaa gacagcatgg gactttacga tgtttgagga aaaatcttaa tgtatcaagc
    14341 actttatcga aaatatagaa gtcaaaactt ctcccagtta gttggtcaag aagttgtggc
    14401 taagactctt aaacaagcgg tggagcaaga gaaaataagt cacgcttatc ttttttctgg
    14461 tcctcgtgga acgggaaaaa ccagtgttgc taaaatcttt gccaaggcta tgaactgtcc
    14521 caatcaagtg ggtggcgaac cttgcaataa ctgctatatt tgtcaagcag tgacggacgg
    14581 tagtttagaa gatgtcattg aaatggatgc agcttctaat aatggggtag atgaaattcg
    14641 cgaaattcgt gataaatcta cctatgcgcc tagccttgct cgttataagg tttatatcat
    14701 agatgaggtt cacatgctgt ctacaggggc ttttaatgcc ctcctaaaga cgctggaaga
    14761 accaacacag aatgtagtct ttattttggc cactactgaa ttgcacaaga ttcctgctac
    14821 tattctatcc cgtgtgcaac gttttgagtt taaatcaatt aagacacagg atattaagga
    14881 acatattcac tatatcttag aaaaagaaaa tatcagttct gaaccagagg ctgtggaaat
    14941 cattgccaga cgggcggaag gtggaatgcg ggacgccttg tctattttgg atcaagccct
    15001 gagtttgaca cagggaaatg agctgacgac tgctatctct gaagaaatta ctggcaccat
    15061 tagcctatca gccttggatg attatgtggc ggccttgtct caacaggatg ttcccaaagc
    15121 tttgtcttgc ttgaatcttc tttttgacaa tggtaagagc atgactcgtt ttgtgaccga
    15181 tcttttgcac tatttaagag acttgttaat tgttcaaaca gggggagaaa atactcatca
    15241 tagttcagtc tttgtagaaa atttggcact tcctcaaaaa aatctgtttg aaatgattcg
    15301 cttagcaaca gtgaatttag cagatattaa gtctagtttg cagcccaaga tttatgctga
    15361 aatgatgacc gtccgtttgg cggaaatcaa gcccgaacca gctctatcag gagcggttga
    15421 aaatgaaatt gctacgctga gacaggaagt tgcccgtctc aaacaagagc tttctaatgc
    15481 aggtgcggtt cctaaacaag ttgcaccagc tcctagtcga ccagctacgg gcaaaacagt
    15541 ctatcgtgtc gatcgcaata aagtgcaatc tatcttacaa gaggccgtcg aaaatcctga
    15601 tttagcacgt caaaatctaa ttcgtttgca gaatgcctgg ggagaggtaa ttgaaagtct
    15661 aggtgggccg gacaaggctc tgctagttgg ttctcaaccg gttgctgcca atgaacacca
    15721 tgctattctt gcttttgagt ctaacttcaa tgctggtcaa actatgaaac gagacaatct
    15781 caataccatg tttggtaata tcctcagtca ggcggcaggt ttttcacctg agattttagc
    15841 tatttccatg gaggaatgga aagaagttcg cgcagccttt tcagccaaag ccaaatcttc
    15901 tcaaactgaa aaagaagtag aagaaagcct gattccagaa ggatttgaat ttttggctga
    15961 taaagtgaag gtagaggaag actaaagaaa gatttcatga tacaataagt ttatgaataa
    16021 acaacaattt attattatgg cgctatttac agctgctgag acctattttt tcaatgaagc
    16081 ctggatgact ggccgctata ttatggcagc cttttgggca attttactct ttagaaattt
    16141 ccgagtcagt tatgtgatgg gtaaaattgt tgatgtcatc gatcagcatt ttaataggaa
    16201 agactagccc tcagcttcca gacaaaatca aagcctttta ggcttttttt tgttatacta
    16261 gaaaagtata tttatagaat ttttgctcta tttctgggga aatcagacgt ttttctagta
    16321 agtactgtaa aagttttgaa aaagaaagga actatcatgt cagtaataga gatcaaagat
    16381 cttcacgttg agattgaagg aaaagaaatt ttaaaagggg ttaacctgac cctgaaaaca
    16441 ggagaaattg ccgctatcat gggaccaaat ggtacaggta aatcgactct ttctgccgct
    16501 atcatgggaa atccaaacta tgaagtaact aaaggtgaag ttttgtttga tggcgtaaac
    16561 atccttgagt tggaagtgga tgagcgtgcg cgtatgggac ttttccttgc tatgcaatac
    16621 ccatcagaaa tccctggaat taccaatgct gagtttcttc gtgccgctat gaatgcgggt
    16681 aaagaagatg atgagaagat ttcagttcgt gagtttatta ctaagctaga tgaaaaaatg
    16741 gaattgctca acatgaaaga agaaatggca gagcgttacc tcaacgaagg cttctctggt
    16801 ggtgagaaaa aacgcaatga aattcttcaa cttttgatgt tggagccaac atttgctctt
    16861 ttggacgaga ttgactcagg tcttgatatt gacgctctta aagttgtgtc taaaggtgtc
    16921 aatgccatgc gtggtgaagg ttttggtgct atgatcatca ctcactacca acgtcttttg
    16981 aactatatca cacctgatgt ggtacacgtg atgatggaag gtcgtgttgt cctttctggt
    17041 ggtccagaat tggctgcgcg tttggaacgt gaaggatacg caaaactagc tgaagaactt
    17101 ggctacgact acaaggaaga attgtaattc cctcgtatct tttaggagaa gtaaatgact
    17161 agagaaaata ttaaactttt ttcagaaatg cacgctgaac caagctggtt ggctgatctc
    17221 cgtcaaaaag cttttgacaa gattgagact ttggaattac cagttattga gcgtgtcaaa
    17281 ttccaccgtt ggaatctggg tgatggaacg attacagaaa atgagccatc agcaaatgtt
    17341 ccagatttca cagctttaga tcatcacttg aagttggtgc aagtaggaac tcaaactgtt
    17401 ttcgaacaaa ctccagttga gttagctgaa cagggtgttg tcttcacaga ctttcactca
    17461 gctttagaag aaattccaga gctgatcgaa gaattcttca tgtcatctgt taagtatgat
    17521 gatgacaagt tggcggctta ccacacagct tactttaaca gtggtgctgt actctatatt
    17581 ccagataacg tagaaatcac agagccaatt gaaggaattt tctaccaaga tagcgatagc
    17641 aatgtgccgt ttaacaagca tattatgatt atcgctggta aaaattctaa gattagttat
    17701 ctggagcgtt tagagtcacg cggtgaagga agtgacaaag taactgccaa tatcacagtg
    17761 gaagtgattg cacgttctgg tgcgcaagtc aagtttgctg ctatcgaccg tctaggtgaa
    17821 aacgtcactg cctacattag ccgtcgtggt aaattaggca acgatgcaag tattgactgg
    17881 gctatcggtg tcatgaacga aggaaatgtc gttgctgatt ttgatagtga cttgattggt
    17941 aatggtagcc atgctgacct caaggttgta gctctttcaa gtggtcgtca ggtacaaggg
    18001 attgatactc gtgtaactaa ctatggctgc aactctatcg gaaatatcct acaacatggg
    18061 gttatccttg aaaaagcaac tttgactttc aatggtatcg gccacatcat caaggatgct
    18121 aagggagcag atgcgcaaca agagagccgt gttctcatgc tttcagacca agcgcgttca
    18181 gatgctaacc caattctttt gattgatgaa aatgatgtca ctgcaggaca cgcagcgtct
    18241 atcggacaag ttgatccaga agacatgtat tacctcatga gtcgtggatt ggataaggca
    18301 actgcagagc gtttggttgt tcgtggtttc cttggatctg ttatcgtgga gattccagtc
    18361 aaggaagttc gtgatgaaat gattgcaact atcgaagaga aattgtcaaa acgctaaggg
    18421 gaagcctatg ttagatgtag aagcgattcg caaggatttt ccaattttag atcagattgt
    18481 caatgatgaa cctctggtct atctggacaa tgctgcgacg acacaaaaac cactagtagt
    18541 tctgaaagct attaacagtt actatgagca ggacaatgcc aatgttcacc gtggtgtcca
    18601 taccttagcg gaacgagcga cagcttctta tgaagctgct cgtgaaacca ttcgtaagtt
    18661 tattaatgca ggctctacaa aggaagttct ctttaccaga ggaacgacaa ccagccttaa
    18721 ctgggtggca cgctttgctg aggaaattct cgctgaggga gaccgggtct tgatttcagt
    18781 aatggaacac cattctaata tcattccatg gcaggaagct tgtcgaaaga ctggagcaga
    18841 gcttgtctat gtctatctta aagacggtgc cttggatatg gaggatttgc gagctaaatt
    18901 gactgataag gttaaatttg tttccctagc tcatgcctcc aatgttcttg gtgtggtcaa
    18961 tccgatcaag gaaatcactc aattagccca ccaagttggg gcaattatgg tagtggatgg
    19021 tgctcaatct acacctcata tgaagattga tgtccaggac ttggatctgg actttttcgc
    19081 cttttcgggt cacaagatgg ctggtccgac tggtatcggt gtcctttacg gcaaagaaaa
    19141 gtatcttgag caaatgtctc cagtagaatt tggcggcgag atgattgatt ttgtctacga
    19201 gcaatttgct agttggaagg aattgccttg gaaatttgag gctggaacgc caaatatggc
    19261 aggagctatt ggacttgcga ctgcagttga ttatctggaa aagattggta tggatgccgt
    19321 tgaagctcat gaacaggaat tgattgcgta cgtctatcca aaactgcagg caattgaggg
    19381 attgaccatt tacggttctc aggatttggc tcaacgttcg ggtgttattg cctttaacct
    19441 aggtgatctc catcctcacg atcttgcgac ggctctggat tatgaaggag tggctgttcg
    19501 tgctggtcac cattgtgcgc aacccttgct tcagtatttg gaagtcccag caacagctcg
    19561 tgcaagtttt tatatctaca ataccaaggc agattgcgac aaactagtcg atgccctaca
    19621 aaagacaaag gagtttttca atggcacttt ctaaactaga tagcctttat atggcagtgg
    19681 tagcagacca ttcgaaaaat ccacatcacc aagggaagtt agaagatgct gagcaaacca
    19741 gtctcaacaa tccgacttgt ggggatgtca tcaacctctc tgtcaagttt gatgcagagg
    19801 accgtttgga agatattgct tttctaaatt caggatgcac gatttcaact gcttctgcta
    19861 gtatgatgac agatgccgtt ttaggaaaaa ccaaacaaga aattttagaa ctggcgacta
    19921 ttttttctga aatggttcaa gggcaaaaag atgagcgtca aggccaactt ggagacgcgg
    19981 cattcttgtc aggtgttgcc aaattccctc aaagaatcaa gtgtgcaacc ctagcttgga
    20041 atgcccttaa gaaaacaatt gaaaatcaag aaaaacagta agacaagttt cttttgtctt
    20101 atgaattatt agaaatgaag aaagaaagga tactatggct gaagaaagag tagaaccaaa
    20161 accaattgac cttggtgaat ataaatttgg tttccatgac gatgtagagc ctgtcttatc
    20221 gacaggaaaa ggactcaacg aaggtgttat tcgtgaatta tctgctgcta agggtgagcc
    20281 tgagtggatg ttggagttcc gtttgaagtc ttatgaaacc ttcaaaaaaa tgcccatgca
    20341 aacttgggga gcagacttgt cagagattga ctttgatgac ttaatctact accaaaaacc
    20401 atctgacaaa ccagcccgtt cttgggatga tgtacctgaa aagattaaag aaacctttga
    20461 acgtatcggg attccagaag ctgaacgtgc ttatttagca ggggcttctg cccagtacga
    20521 gtcagaagtg gtttaccaca acatgaagga agagttccaa aaattaggta ttatctttac
    20581 agatacagat tccgcactca aggaataccc agacttattt aaacaatact ttgcgaagtt
    20641 ggtaccgccg acagataaca agttggcagc cctcaactca gcagtatggt cgggtggaac
    20701 ttttatctac gtgccaaaag gtgtcaaggt agatattcca cttcaaactt atttccgtat
    20761 caataacgaa aatataggtc agttcgaacg taccttgatt atcgttgatg agggagcaag
    20821 cgtccactac gtagaaggat gtacagcacc aacatattca agcaatagct tacacgctgc
    20881 cattgtagaa atttttgctt tggacggagc ttatatgcgt tatacaacta tccaaaactg
    20941 gtctgataac gtctataact tggtaacaaa gcgtgctaag gctcaaaagg atgccactgt
    21001 tgagtggatt gatggaaact tgggtgccaa aacgactatg aaatatccat ctgtttacct
    21061 tgatggagaa ggagcgcgtg gtaccatgct ctctatcgcc tttgctaatg cagggcaaca
    21121 ccaagacacg ggtgctaaga tgattcacaa tgctccacat accagctcgt ctattgtgtc
    21181 taaatccatc gctaaaggtg gaggaaaggt tgactaccgt ggacaagtca cctttaacaa
    21241 gaactctaag aaatctgttt cccacattga atgtgatacc attatcatgg atgacttgtc
    21301 agcatcagat actattccat ttaatgaaat tcacaactcg caagtggctt tggaacacga
    21361 agccaaagta tctaagattt cagaagagca attgtattat ctcatgagcc gtggattgtc
    21421 agaatctgag gcaactgaaa tgattgtcat gggatttgta gaacccttta caaaagaact
    21481 tccaatggaa tacgcagttg agctgaaccg cttgattagc tatgaaatgg agggatcagt
    21541 tggataaaat ttgattttat actcttcgaa aatctcttca agccacgtca gcatcgcctt
    21601 accgtatgta tggttactga cttcgtcagt ttcatctaca acctcaaaac agtgttttga
    21661 gcaacctgcg gctagcttcc tagtttgttc tttgattttg agtattagat ttactcaaaa
    21721 tcaaggattt tgaagatgaa cttgtatcaa aaaatcgcgg tttaaaatcg cgatttttta
    21781 taatttctcg ttaacaaagc ggacaaactg attccaccaa acttttaaga agaaggcttt
    21841 ttcaattttc ttgtctgcta ccatttcgaa actagggcgc tctgtggtga tgtaaccttg
    21901 accaatcaag tccttgtctt cataagtcaa atggccaacc actgttccag cttcaagtgg
    21961 tgctgggatt gctttggaat caggtgtgaa ttgaacagat tgggaagatt gattcccaat
    22021 ctgttcgatt agatagatat cctctggagc cactgcagtt actgtatctt cttttccatc
    22081 ttgtacaggg gctttgctat cttgataggc atcgccttgt tgaacgattt tgcgaagtgt
    22141 aaatgtagaa gaaatataat ccattaggga agatgtagct gtaaatcgag cgtaaggatt
    22201 attgtcttga tgatctgcat ttaaaacaac tgtgatgact ctcatgcctt tttcgacagt
    22261 agtaccaaca aaagactctc cagccttatc tgttgttcct gtttttagcc catcaaaacc
    22321 accacggtaa gcaggcatac cttctaacat gtagttggtt gaagtgattg tcatcccagc
    22381 aaaagtagaa gaaggttttt tggtgatttc taagacttgt gggtattttt tgatgaggtt
    22441 gcgagcaacg atagcgacat cataagcact aagcttattt tcctcatctt ttttagaacc
    22501 tgggtaaatg ttatccccta gagtttcatt gttaagacct gtcgtattga caacagtggc
    22561 atcctgaatt ccccattcca agagttttgc ccgcatcata tcgacgaaat ctttttctga
    22621 gccagcaatt ttctcagcta gggcaatagc ggcgctgttg gcactagata ccagagttgc
    22681 ttcaagcaac tcttcgacag tataattacg ggcctccata ggaatattac tggcttcaga
    22741 atttgtcgtc aattgataag gataatcaga aatatctaca ggagtggaga gggtaatact
    22801 tccgttttcc aaagcttcat agaccagata aacagtaatc aattttgtta tggaagcaat
    22861 ttcgacaggt tgcgttgcat ccttctcata gagaatttta ccagtatttg cctcaacagc
    22921 aatcgcatgt ttagcggcaa tggtaaaatc ttgagcaaca gcagtagaag caccccctaa
    22981 aagagagaca gttaacaaag ttaaaaatat ttttttcata gtagtcttat tctatcataa
    23041 agaaaaaaaa tattcttgct ttaataattc atctgttaag ctttttgaaa atatggtaaa
    23101 ataaagtgag ggaggtaact catgtttcgt agaaataaat tatttttttg gaccacagaa
    23161 attttactct taaccatcat cttttaccta tggagacaga tggggtcttt gattaaccct
    23221 tttgttagcg tgcttaatac aattatgatt ccatttttat taggggtctt tctttattat
    23281 ttgacaaacc ctattgttac tttcttaaat aaagtctgta aactcaatcg tttgcttggt
    23341 attttaatta ccttgtgtac tttggtctgg ggaatggtca taggtgttgt ctatctctta
    23401 cctattttga ttaatcagtt atctagtttg attatatcta gtcaaactat ttatagtcga
    23461 gtacaagact taatcataga cttatctaat tatcctgcgc tccagaattt ggatgtagaa
    23521 gctacaattc agcagttaaa cttatcctat gttgatattc ttcaaaatat cctaaatagc
    23581 gtatcaaata gtgtggggag cgtcttgtca gctcttatca gtactgtttt gattttgatt
    23641 atgactccag tttttttggt ttatttctta ttagatggac ataaattctt gcccatgctt
    23701 gaaagaacga ttctaaagag ggatcgcttg catattgcag gcttattaaa gaatttaaat
    23761 gcgacgattg ctcgctatat tagtggagtt tcgattgacg caatcattat aggttgttta
    23821 gcttatattg gctatagtat tattggttta aaatatgctt tagtttttgc cattttttct
    23881 ggtgtagcca atttaattcc ttatgtgggg ccaagtattg gtttgattcc tatgatcatc
    23941 gcaaatatat tcactgatcc ccatagactg ctgattgcag tgatttatat gcttgttgtt
    24001 cagcaggtag atggcaatat cttatatcct cgaatcgtag gaagtgttat gaaggttcat
    24061 ccaatcacga ttttagtttt acttttgttg tcaagcaata tttatggtgt agttggaatg
    24121 attgtcgcag tgccaaccta ttctatcttg aaagaaattt ctaagttctt atcccgtttg
    24181 tatgaaaatc ataaaataat gaaagaacga gaaagagaat tagctaagta aaagtcagga
    24241 gaaccctgat ttttctttac tggaagtggc ctttagatta gaagactgaa aataagttaa
    24301 agtcttaaac taattttcac agctaagaat agtagaagtt aatctgataa aaatcgaaaa
    24361 aaccagtgga attctgtgtc agggtaagtt ccactggttt tcatagtcta ttaaagttcg
    24421 aatgaaacct atttatagta gattgaaact agaatagtac acctctaatt ctaaaacatt
    24481 gttagaaatc gatttgactg tcctgatcta ttcgtcctat tcttatttca ttttactata
    24541 ttttggtgca ataagtgaaa agtagtccga ataatataag gattgatttt atagttttta
    24601 aactcaaatg aattaaaata aagagagtac gaaaattctc atctgaaagt attttagaat
    24661 aattctcttc gtgaatttct tcaaaacaga tagcttcatc ttaggtatgt gttaattgga
    24721 tttcgtaagc tctatttaca atcgtaaagt tatgcactga gaaagttgta gttagtcttc
    24781 cagtttgcta aatttctcga atagtatctt ttttaggtat gtgatttctt tttgcatttt
    24841 tgagttagat aaggtataat ggttttattg tcttttgggg tcgttacgga ttcgacaggc
    24901 attatgaggc atattttgcg actcgtgtgg cgacgtaaac gctcagttaa atataactgc
    24961 aaaaaataac acttcttacg ctctagctgc ctaaaaacca gcaggcgtga cccgatttgg
    25021 attgctcgtg ttcaatgaca ggtcttatta ttagcgagat acgattaagc cttgtctagc
    25081 ggcttgataa gagattgata gactcgcagt ttctagactt gagttatgtg tcgaggggct
    25141 gttaaaataa tacataacct atggttgtag acaaatatgt tggcaggtgt ttggacgtgg
    25201 gttcgactcc caccggctcc attattcctt tgcattcttt tgcattcctt ggtaaaacgt
    25261 tgttaaatca acgtttttta tttttatctt tggtattcct ttgcattctt ttgctaaaaa
    25321 gggagtcaca aacagaccct attttaaaaa aggatacaac atttgttgca tcctaaaaat
    25381 aatctttttt cgacggaaga catgggattc gaacccacgc acgctattac acgcctaccg
    25441 cgtttccaac acggcctctt aagcctcttg agtaatcttc caatacttac tcaaatagtc
    25501 taccataaag gctcttatct tgcaataaaa attctagaaa taagaaaaat gatagatttt
    25561 gaaagaaaat gataaaaaat gcttgacttc gaaataaagt atggtagaat gaatagtgta
    25621 aacgataaca ggaggtgatt cagtgttaaa aacagaacgt aaacaactga ttctagagga
    25681 gttaaatcaa catcatgtag tttctctaga aaaattagtt agtttgctag aaacgtcaga
    25741 atcaacggtt cgaagagact tggatgagtt ggaagcggaa aacaagcttc gtcgtgtgca
    25801 tggtggagca gaactccccc actccttaca ggaagaagaa accattcaag aaaaatctgt
    25861 caaaaacctt caagaaaaga agttgctggc tcagaaagca gcctctctca ttaaagaaaa
    25921 agatgtcatc tttatcgatg ctggaacaac aactgctttt ttgattcatg aattggtcaa
    25981 taagaatgtt acagttgtga ccaactccat tcaccatgcc gctcagttgg ttgaaaagca
    26041 gattccaact gtcatggttg gaggaaacgt caagacggcg acagatgcta gtatcggggg
    26101 cgttgctctt aaccagatta accaattgca ctttgaccgt gcctttatcg gaatgaatgg
    26161 tgttgacgat ggctattata cgactcctga tatggaggag ggagctgtga aaagagctat
    26221 tttggagaat gccaagcaga cctacgtctt ggtggattcg tcaaaaattg gacaaacttg
    26281 ctttgccaag gtagcaccac tcaaacgcgc tatcgttatc actagtcaag ggcatgagct
    26341 cttgcaggtt attaaggaga aaacggaggt aatagaagta tgatttatac agtcacactc
    26401 aatccatcca ttgactatat cgttcgtttg gaccaagtca aagttggtag tgtaaatcgt
    26461 atggacagtg atgataagtt tgctggtggg aaaggaatca atgtcagccg tgtcttgaaa
    26521 cgtttgaata taccaaatac agcgacggga tttatcggtg gctttactgg taaatttatc
    26581 acagatactt tagcagagga agaaatcgag acacgttttg tccaggtggc agaagatact
    26641 cgtatcaatg ttaaaatcaa agcagaccaa gaaacagaaa tcaacggaac gggtccaact
    26701 gttgaatcgg ttcagctaga agaattgaaa gctattttat ctagtctgac agcagaagat
    26761 acagttgtct ttgcaggttc aagtgctaaa aatctaggca atgttatcta taaggatttg
    26821 atttccttga cgcgccagac tggtgcgcaa gtggtctgtg actttgaagg acagacctta
    26881 attgatagtt tggactacca gcctcttctt gtaaaaccaa acaatcatga acttggagcg
    26941 atttttgggg ttaaactcga aagtttagat gaaattgaga aatacgctcg tgagttactg
    27001 gctaagggtg ctcaaaatgt tattatctct atggctggtg atggtgccct tcttgtcaca
    27061 tctgatggag cttacttcgc taaaccaatc aagggaacag tcaaaaattc agttggagct
    27121 ggtgattcta tggttgctgg attcacaggt gaatttgtca aatcaaaaga cgcagtagaa
    27181 gccttcaaat ggggagtggc ttgcggaacg gcaactacct tctcagatga cttggcaacg
    27241 gcggaattta ttaaagaaac atatggaaaa gttgaggtag aaaaacgatg aaaattcaag
    27301 acctattgag aaaagatgtc atgttgctag atttgcaggc aactgaaaaa acagctgtca
    27361 tcgacgagat gattaaaaat ttgacagacc acggttatgt aacagatttt gaaacattta
    27421 aagaaggcat tttggcgcgt gaagctttga cttctactgg tttgggtgat ggaatcgcaa
    27481 tgcctcacag caaaaacgct gctgtcaaag aagcgacagt tctatttgct aagtcaaata
    27541 agggtgttga ctacgagagc ttggatggac aagcaactga cctcttcttc atgattgcag
    27601 ctccagaagg tgccaatgat actcacttgg cagccttggc agaattgtct caatacttga
    27661 tgaaagacgg ttttgcagac aaacttcgtc aagcaacatc tgcagaccaa gttatcgaac
    27721 tttttgacca agcttcagaa aaaactgagg aacttgttca agcacctgct aatgactctg
    27781 gtgactttat cgtagctgtt acagcttgta caacaggtat tgcccacact tacatggccc
    27841 aagaagccct tcaaaaagta gctgctgaaa tgggggttgg tatcaaggtc gaaaccaacg
    27901 gtgctagcgg tgttggaaat caactaactg cagaagatat ccgtaaggct aaagctatta
    27961 tcattgcagc agacaaggcc gttgaaatgg atcgatttga tggaaaacca ttgatcaatc
    28021 gtccagttgc tgacggtatc cgtaagacag aagagctaat taacttggct ctttcaggag
    28081 atactgaagt ctaccgtgcc gctaatggtg ccaaagctgc aacagcctct aacgaaaaac
    28141 aaagccttgg tggtgccttg tacaaacact tgatgagtgg tgtatctcaa atgttaccat
    28201 tcgttatcgg tggtggtatc atgattgccc ttgccttctt gattgacggt gctttgggtg
    28261 ttccaaatga aaaccttggc aatcttggtt cttaccatga gttagcttct atgttcatga
    28321 aaattggtgg agctgccttt ggtttgatgc ttccagtctt tgcgggttat gttgcctact
    28381 ctattgctga aaaaccgggt ttggtagcag gtttcgtggc tggtgctatt gccaaagaag
    28441 gttttgcctt tggtaaaatt ccttatgccg caggtggtga agcaacttca actcttgcag
    28501 gtgtctcatc tggtttccta ggtgcccttg ttggtggatt tatcgcaggt gccttggttc
    28561 ttgccatcaa gaaatacgtt aaagttcctc gttcactcga aggtgctaaa tcaatccttc
    28621 tattgccact tcttggaaca atcttgacag gatttgttat gctagctgtg aatatcccaa
    28681 tggctgcaat caacactgct atgaatgact tcctaggcgg tcttggagga ggttcagctg
    28741 tccttcttgg tatcgtcctt ggtggaatga tggctgttga catgggtgga ccagttaata
    28801 aagcagctta tgtctttggt acaggtacgc ttgcagcaac tgtttcttca ggtggttctg
    28861 tagccatggc agcagttatg gctggaggaa tggtgccacc acttgcaatc tttgtcgcaa
    28921 ctcttctttt caaagataaa tttactaagg aagaacgtaa ctctggtttg acaaacatca
    28981 tcatgggctt gtcatttatc actgagggag cgattccatt tggtgccgct gacccagctc
    29041 gtgcgattcc aagcttcatc cttggttcag cagtagcagg tggactcgtt ggtcttactg
    29101 gtatcaaact catggcgcca cacggaggaa tcttcgttat cgcccttact tcaaatgctc
    29161 tcctttacct cgtttctgtc ttggtaggag caatcgtaag tggtgtggtt tatggttacc
    29221 tacgcaaacc acaagcataa aaaatagaaa aatgaaaaga ttggaccgtt tggtgcagtc
    29281 tttttctctt cccgaaatgc ctgtgaaata tggtataata gaagaatggc aaacaagaat
    29341 acaagtacaa caagacggag accgtctaaa gcagaactgg aaagaaaaga agcgattcaa
    29401 cgaatgttga tttcattagg aattgcgatt ttattgattt tcgcagtctt caaattaggg
    29461 gctgcaggta taacccttta taatttaatt cgcttgctag tgggtagcct agcttatctg
    29521 gcgatattcg gcctattaat ctatctcttc tttttcaagt ggatacgaaa acaggaagga
    29581 ctcttatctg gctttttcac catatttgct ggcttactct tgatttttga agcctacttg
    29641 gtttggaaat atggtttgga caagtccgtt ctaaaaggga ccatggctca ggttgtgaca
    29701 gatctgactg gttttcgaac gactagcttt gctggagggg gcttgatagg ggtcgctctt
    29761 tatattccaa cagcctttct cttttcaaat atcggaactt actttattgg ttctatcttg
    29821 attttagtgg gttctctcct agtcagccct tggtctgttt acgatattgc tgaatttttc
    29881 agtagaggct ttgccaaatg gtgggaaggg cacgagcgtc gaaaagagga acgctttgtc
    29941 aaacaagaag aaaaagctcg ccaaaaggct gagaaagagg ctagattaga acaagaagag
    30001 actgaaaaag ccttactcga tttgcctcct gttgatatgg aaacgggtga aattctgaca
    30061 gaggaagctg ttcaaaatct tccacctatt ccagaagaaa agtgggtgga accagaaatc
    30121 atcctgcctc aagctgaact taaattccct gaacaggaag atgactcaga tgacgaagat
    30181 gttcaggtcg atttttcagc caaagaagcc cttgaataca aacttccaag cttacaactc
    30241 tttgcaccag ataaaccaaa agatcagtct aaagagaagg aaattgtcag agaaaatatc
    30301 aaaatcttag aagcaacctt tgctagcttt ggtattaagg taacagttga acgggccgaa
    30361 attgggccat cagtgaccaa gtatgaagtc aagccggctg ttggtgtaag ggtcaaccgc
    30421 atttccaatc tatcagatga cctcgctcta gccttggctg ccaaggatgt ccgaattgaa
    30481 gcaccaatcc ctgggaaatc tctaatcgga attgaagtgc ccaactccga tattgccact
    30541 gtatctttcc gagaactatg ggaacaatcg caaacgaaag cagaaaattt cttggaaatt
    30601 cctttaggga aggctgttaa tggaaccgca agagcttttg acctttctaa aatgccccac
    30661 ttgctagttg caggttcaac gggttcaggg aagtcagtag cagttaacgg cattattgct
    30721 agcattctca tgaaggcgag accagatcaa gttaaattta tgatggtcga tcccaagatg
    30781 gttgagttat ctgtttacaa tgatattccc cacctcttga ttccagtcgt gaccaatcca
    30841 cgcaaagcca gcaaggctct gcaaaaggtt gtggatgaaa tggaaaaccg ttatgaactc
    30901 tttgccaagg tgggagttcg gaatattgca ggttttaatg ccaaggtaga agagttcaat
    30961 tcccagtctg agtacaagca aattccgcta ccattcattg tcgtgattgt ggatgagttg
    31021 gctgacctca tgatggtggc cagcaaggaa gtggaagatg ctatcatccg tcttgggcag
    31081 aaggcgcgtg ctgcaggtat ccacatgatt cttgcaactc agcgcccatc tgttgatgtc
    31141 atctctggtt tgattaaggc caatgttcca tctcgtgtag catttgcggt ttcatcagga
    31201 acagactccc gtacgatttt ggatgaaaat ggagcagaaa aacttcttgg tcgaggagac
    31261 atgctcttta aaccgattga tgaaaatcat ccagttcgtc tccaaggctc ctttatctcg
    31321 gatgacgatg ttgagcgcat tgtgaacttc atcaagactc aggcagatgc agactacgat
    31381 gagagttttg atccaggtga ggtttctgaa aatgaaggag aattttcgga tggagatgct
    31441 ggtggtgatc cgctttttga agaagctaag tctttggtta tcgaaacaca gaaagccagt
    31501 gcatccatga ttcagcgtcg tttgtcagtt ggatttaacc gtgcgacccg tctcatggaa
    31561 gagcttgaga tggcaggtgt cattggtcca gctgaaggta ccaagccaag aaaagtattg
    31621 cagcaataaa aaatagcttc tttccaagtt tggaaggagg ctattttagt gattattgat
    31681 tagttttatt ttccgaagtt ggggtattgg actgtttttc gttttcagta gcaggtttac
    31741 ttggagtagg agcaggagta gaagaatcct gagttgatgt tttctgctct tcttttttct
    31801 cttccttgac gctggatttt ggcgtttctt cttgttgtgt tttttcttga gaagtcttat
    31861 tttccttatt gggactagta ttttcctgag gggattcctt ttgaatttct ttgacaattg
    31921 ttgtcgtctg gcttgttgta ggttcctttt tagtattttt gttattatcc aaggcgttca
    31981 taatcgtgat actagcggta atcaagccaa ggatactagc gatagtcgca acggtttttt
    32041 gaaagactgt aaagcctttt ttgatgtgtt ctgtttttgg ttttgaagtt ctacgataat
    32101 tagacataca ttctctcctt taattaaaat ttattatacc tcatttcttt aaaaaaatct
    32161 taaaaaaaga ggagattttt ctacacgaac ttcagtaatt agttgaaata aaatatgact
    32221 tatgatataa caaaataaag aaagcgattt caaaaaagga gggcgttata tgttcgaaat
    32281 tagaaatttg agtctctctt ttgcaggcag gcggttgcta gagccaacag atttgatatt
    32341 tgaaagggga aaagtatata caatatatgg gaagtcaggc gtaggaaagt cttctttact
    32401 gaataaaatt ggtttgctct ctgctacgga tcctagtgtt tcttatttct tcgatggaaa
    32461 agagattgat atcgaaaata agaaatcagt ctctgtcttt atagctgaag aagttgcctt
    32521 tgtatttcag gggcgaaatc taataaatga tttgaccgta tttgaaaatt taagactagc
    32581 tttaaacttt tatgacttga gtccagatga aatagaaagc aaaattgata cagtattggc
    32641 ggatttacag atttcttctt taaagcatgc ttatccagaa gatttatccg gtggtgaaga
    32701 acaacgagtg gcaatcgcaa gagccttagt tacaggaaag actctcatct tagctgatga
    32761 accaacaagt tctttggata aagaaaatag agaaaaaatc tccgccttgt taattgattt
    32821 agctcacaaa tatcataaaa ttgtattgat tgtttcgcat gatgaggcga tgattgcaat
    32881 aggagatgtt cagcttcatt ttaaagacca taaattagtt gggaattgtc ttattttgaa
    32941 ttctgatgaa gggataaagg attctaagaa gtggtcctcc tgtttgtcgt cttctcatac
    33001 gaagctatcc gttttgaaac atagaaggcc ttttttacct agattattag cgttttttat
    33061 ctctcttgta gttgctatag cagtaacctc tattaacttt cagtccttat ttgcagataa
    33121 gtatcaccaa ctggtgaaca actcactcga aaatggcttc ttggtgatta atgattcgct
    33181 tcatttacaa actacaaaag tgttggatga ttttctcagt tttgataagg aggaaatcac
    33241 ctcaattagc acaagtcaga atattcaaac cgtcaatcct tatatagagt ttctctcttt
    33301 gggtatgacg tttgataatt caaaagacta ttcacaactt caaaagaact ttcagccaac
    33361 tttgactatt gatggtcaga ccagaagctt gacaagaaat ttttcaattc aacccttgta
    33421 tcagacaaat acaacacaga ggcagataga gtattttgat aggagcaatg aaaaagggat
    33481 ttatctatct gagcaattca tttcagatga aaaattacca aatatagttt cgggaactac
    33541 cgtgacactg actttttata ttccaatttc tttatatgaa tcaagtatag agaaagaggg
    33601 gaatatattg aaaggagatg gcggtttatt tgtcaaagtg gataaaacat atcctgtttt
    33661 agggattgtt aaaaaaagtt atccgtttga atattcccct tatgggaaca ccctatttat
    33721 gaatattgct gaaatggaag aattgcaaaa tgaagcaatt caacagcatc ccatgacgaa
    33781 gatggcttta gatggttttc ctttgaaatc atggatgccg agtgcgattc atgtgttact
    33841 aaaggatagc ggtgctattc ctgaagaatt gagtagaata agagcaatct cttcacaaat
    33901 tactatttta tcatcatatg aaaactacga agaatttaat aaaggactca cctatatcag
    33961 gcaattttta atgttgctat ccctagtctt actcatcctt gtcatcgcag tattgtcctt
    34021 tgttttcttt ttgctcaatc gtcctcgacg ctttgaagta gggattttaa aatctttggg
    34081 atacagtact caaaatattg tttggctttt cttaaaagaa ttaattggtt atggtaaaac
    34141 aatttcgata ttagcaagtt gtttactcgt cattctttcc attttagcaa tgcaagtgct
    34201 taaattggaa atttcagatg tttttaaatt ctatctaact tccgttttca ccttaattgg
    34261 attatcagtc tcagtactga taataagtgg cttactacct atatacacaa cttgtaggca
    34321 aacagttgtc gatactatcc gaaagaatgg atgaggtgat atcatgaaac ataagataat
    34381 gaaaaaaata atagtggtag tgtttgctat cccatggtta acatttttaa gtcaagtaca
    34441 tgcagattat gtaagtaagt ctagttcttt agacggttat agcttggtag gcttgaatgt
    34501 tcttaatgtg acttttaatg cttctggcta ttctgatact tatagtggca gtgtgtcaaa
    34561 tatgtatttc actgactggg cttggtttcc taatacgata agtaatcgtt ccacttggaa
    34621 aagttcgatt ccatatggtc aacgcgcaaa tggtacagtc catataggtg taggagtaaa
    34681 ttcgccttgg ggagcggtta atctctgggg cggacaaaat tacttttctt tagattttta
    34741 acagaaataa tcaaagttag atagaatgaa taagaatgct cttgatgatg gtatcaagag
    34801 tattttatgt tattcagatt aatgcaaaca ttgccctttc ttgtcgcagg ctccgtttca
    34861 tgatacaata gaaggagtga ttttagaaag cgtgagaaac atgatttact ttgataattc
    34921 ggcgacgacc aggccctatc cagaagccct tgaaacctat atgcaggtgg cttcaaaaat
    34981 tttaggaaat ccatctagtc tccatcgttt gggagaccag gcaacacgaa ttttagatgc
    35041 ttcccgtcaa cagattgcag atttaatcgg taagaaaagt gatgaaatct tctttacatc
    35101 tggtgggaca gaaggggata actggatcat caagggagta gcatttgaaa aagcccagtt
    35161 tggcaagcac atcatcgtat cagccattga acatccagca gttaaggaat cagccctctg
    35221 gttgaaagct caaggttttg aagtggattt tgctccagtt gataacaaag gatttgtgga
    35281 tgttgaggtg ctagaagatt tgataagacc tgatacgacc ctcgtttcca tcatggcagt
    35341 taacaatgaa attggctctg ttcagcccat tgaggctatt tcaaaactat tggcagacaa
    35401 gccaactatt tccttccacg ttgatgcggt tcaggcgctt gccaagattc cgactgaaaa
    35461 gtatctgaca gaacgagtgg atttcgcgac tttctctggt cacaagttcc acggaatccg
    35521 tggtgttggt tttatctata tcaagtctgg caagaagatt acgcctcttt taacaggtgg
    35581 tggtcaggaa cgtgattacc gttcgacaac tgaaaatgtg gcaggaattg cagcgaccgc
    35641 taaggctctc cgtttatcta tggaaaagct agatatcttt aggagcaaga ctgggcagat
    35701 gaaggcagtg attcgtcaag cacttctgga ctatccggat atatttgtct tttcagatga
    35761 ggaagacttc gcccctcata ttctgacttt tggaatcaag ggtgttcgtg gtgaggtcat
    35821 tgttcacgcc tttgaagact atgatatttt catctcaacg acctcggctt gttcgtccaa
    35881 ggctgggaaa ccagccggaa ccctgattgc tatgggagtg gacaaggata aggctcagtc
    35941 agctgtgcgt cttagtctag accttgaaaa tgatatgagt caggtcgagc agttcttgac
    36001 caagctaaaa ttaatttaca atcaaactag aaaagtaaga taggagcatt catgcagtat
    36061 tcagaaatta tgattcgcta cggtgagctg tcaaccaagg gcaaaaatcg tatgcgtttc
    36121 atcaataaac ttcgcaataa tatttcagac gttttgtcta tctatcccca agttaaggta
    36181 acagcagatc gcgaccgtgc ccacgcttac ctcaatggag cagattacac agcagtagca
    36241 gaatcgctca aacaagtatt tggaattcaa aacttttccc ctgtttataa ggttgaaaaa
    36301 tctgtagaag ttctgaagtc tgctgtccaa gagattatgc aggacatcta caaggaaggc
    36361 atgaccttta aaatctctag caagcgtagc gaccacacct ttgaattgga cagtcgtgaa
    36421 ctcaaccaaa cgcttggagg ggctgtattc gaagccattc caaacgtaca agctcaaatg
    36481 aaaagtcctg acatcaatct tcaggtggag atacgtgaag aagcagccta tctttcttat
    36541 gaaaccgttc gaggggcagg tggattacca gtgggaactt ctggtaaggg catgctcatg
    36601 ttgtcagggg gaatcgattc ccctgtagct ggctatctag cgcttaaacg aggggtagat
    36661 atagaggcag ttcactttgc cagcccacct tacacgagtc ctggtgctct taaaaaagcc
    36721 caagatttga cccgtaaatt aaccaaattt gggggaaata tccagtttat cgaagttcct
    36781 tttacagaga ttcaagagga aatcaaagcc aaagcgccag aagcctacct tatgaccttg
    36841 acgcgtcgtt ttatgatgcg tattactgac cgtattcgtg aggtacgaaa tggtttagtt
    36901 atcatcaatg gggaaagtct aggtcaagta gccagccaaa cccttgaaag tatgaaggct
    36961 atcaatgctg ttaccaacac tcccatcatt cgtcctgtgg ttaccatgga caagttggaa
    37021 atcattgaca tcgcccagga aatcgatacc tttgacattt caatccaacc gtttgaagac
    37081 tgttgtacca tttttgcacc agatcgtcca aaaacaaatc ctaaaattaa gaatgcggag
    37141 cagtacgaag cgcgtatgga tgttgaaggc ttggttgagc gagcagtggc tggaatcatg
    37201 attactgaaa tcacacctca agccgaaaaa gatgaagttg atgacttgat tgacaatctg
    37261 ctctaattca gaaaatccaa aagaatagcg aaaatcagta aaaaaagtta gttttttctc
    37321 taaaaacagg taaaaaacta acttttttta tttttatgat ataatgatat aaaattttga
    37381 atatagagag ttttctgaca atgaatcaat cctactttta tctaaaaatg aaagaacaca
    37441 aactcaaggt tccttataca ggtaaggagc gccgtgtacg tattcttctt cctaaagatt
    37501 atgagaaaga tacagaccgt tcctatcctg ttgtatactt tcatgacggg caaaatgttt
    37561 ttaatagcaa agagtctttc attggacatt catggaagat tatcccagct atcaaacgaa
    37621 atccggatat cagtcgcatg attgtcgttg ctattgacaa tgatggtatg gggcggatga
    37681 atgagtatgc ggcttggaag ttccaagaat ctcctatccc agggcagcag tttggtggta
    37741 agggtgtgga gtatgctgag tttgtcatgg aggtggtcaa gccttttatc gatgagacct
    37801 atcgtacaaa agcagactgc cagcatacgg ctatgattgg ttcctcacta ggaggcaata
    37861 ttacccagtt tatcggtttg gaataccaag aaaaaattgg ttgcttgggc gttttttcat
    37921 ctgcaaactg gctccaccaa ccgctatatc gagtgccaga aactatcgcc tgaccaacgc
    37981 atcttcatct atgtaggaac agaagaagca gatgatacag acaagacctt gatggatggc
    38041 aatatcaaac aagcctatat cgactcgtcg ctttgctatt accatgattt gatagcaggg
    38101 ggagtacatc tggataatct tgtgctaaaa gttcagtctg gtgccatcca tagtgaaatc
    38161 ccttggtcag aaaatctacc agattgtctg agattttttg cagaaaaatg gtaagttaag
    38221 aaaggaaaaa acgaaatgca tattgaacat cttagccact ggagtggtca tcctaaccgt
    38281 gaaatgtacc ttaaccgtta tggacatggt gggattccag ttgtggtctt tgcttcatca
    38341 ggtggtagtc acaacgaata ctatgatttt ggcatgattg atgcctgtgc ttcctttatc
    38401 gaggaaggcc gtgtccagtt ctttacccta tctagtgtgg atagtgagag ctggttggct
    38461 acttggaaaa atgctcatga ccaagcggaa atgcaccgtg cctacgaacg ttatgtgatt
    38521 gaggaggcca ttcttttatc aagcacaaga caggttagtt tgatggcatg atgacgacag
    38581 gttgctctat gggagcctat catgcactca atttcttcct ccagcatcca gatgtcttta
    38641 ccaaagtgat tgctctcagt ggtgtttacg acgcacgttt ctttgtcggt gattactaca
    38701 acgatgatgc tatttaccaa aactcgccag tagattatat ttggaaccaa aacgatggct
    38761 ggtttattga ccgttaccgt caggcagaga ttgtgctgtg tacggggctt ggagcctggg
    38821 aacaagatgg tttaccatcc ttttacaagc tcaaagaagc ctttgaccag aaacaaattc
    38881 cagcctggtt tgctgaatgg ggacatgatg tcgcccacga ctgggaatgg tggcgtaaac
    38941 aaatgcctta tttcctcggt aatctctatt tataaaagga gttacctatg aattaccttg
    39001 ttatttctcc ctactatcca caaaactttc aacagtttac catcgaacta gctaataaag
    39061 gcatcacagt cttgggaatt ggtcaagagt cttacgagca attggatgag cccttgcgca
    39121 atagcttgac cgagtatttt cgtgttgata atcttgagaa catagatgaa gtcaaacgtg
    39181 cagttgcttt tctcttttat aaacatggtc caattgaccg catcgagtct cacaatgaat
    39241 actggcttga gctagacgca acactcagag aacaattcaa tgtttttggt gccaaaccag
    39301 aggatctcaa aaagacgaaa tataagtctg aaatgaagaa acttttcaaa aaagcaggtg
    39361 ttcctgtggt acctggagct gttatcaaga cggaagcaga tgttgatcaa gcagtgaaag
    39421 aaatcggtct tccaatgatt gccaaacctg ataatggagt gggagcagcc gcaaccttta
    39481 aacttgagac agaagacgat atcaatcact tcaagcaaga atgggaccat tcaacccttt
    39541 atttctttga aaaatttgtc acttccagcg aaatctgtac ctttgacggg ctcgtggaca
    39601 aggatggaaa gattgtcttc tcaacaacct ttgactacgc ctatacaccg cttgacctca
    39661 tgatttataa gatggacaat tcttattatg tgctcaagga tatggatcct aaactgcgca
    39721 agtatgggga agcaattgtc aaagaatttg gtatgaaaga acggtttttc catattgagt
    39781 tcttccgtga gggggacgat tatattacca tcgagtacaa taaccgccct gcaggtggtt
    39841 ttaccattga tgtttataac tttgctcatt ccttggacct ttatcgtggc tatgcagcta
    39901 ttgtcgcagg agaggagttc ccggcgtcag actttgaaac tcagtattgt ttggctactt
    39961 ctcgccgtgc aaatgctcac tatgtttatt cagaagagga tttgcttgcc aaatatagcc
    40021 agcagttcaa ggttaaaaaa gtcatgccag ctgccttcgc ggaacttcaa ggagattacc
    40081 tgtatatgct gacaactccg agtcgacaag aaatggatca gatgattgct gatttcggac
    40141 aacgtcaaga ataagaacta tcggattaag gaaattcact cccttaatcc ttttgttttg
    40201 tctggtaaaa aataagagca tcctaacaag gtagctatca taaaacttgt tcgataacta
    40261 tttgaagcag gattaggtgg ctagaaattg aattttaaca tttcaattta gtcatagtat
    40321 tgtgttttcg tatccttaaa tcagctaaaa ggatccatga cgacacctat acgatatagt
    40381 tttcaggata ccaaaccagt ctattaatac tcaatgaaaa tcaaagagca aactaggaag
    40441 ctagccgcag gttgctcaaa acactgtttt gaggttgtgg atagaactga cagagtcagt
    40501 atcatatacc tacggcaagg tgaagctgac gtagtttgaa gagattttcg aagagtataa
    40561 atcttattga tgaactgctt gcagtctgag aaaaaatgag cttggatatt atttccaaac
    40621 tcacttaaag tcaatttcaa tccactagaa caagcctagt acagttccat cgctttcaac
    40681 atccatgttg agagctgctg gacgttttgg aagacctggc atggtcataa catcaccagt
    40741 taaggcaacg atgaagcctg cacctaattt tggtaccaat tcacgaatgg taatttcaaa
    40801 gttttctggt gctccaagcg catttggatt gtctgagaaa ctgtattgag ttttagccat
    40861 acaaattggc aatttgcccc aaccattttg aacgatttga gcaatttgtg tttgagcttt
    40921 cttctcaaag ttcactttgc taccacgata gatttcagtg acaatttttt caatcttttc
    40981 ttggacagaa aggtcattat cgtacaaacg tttatagtta gctggatttt cagcaattgt
    41041 cttaacaact gtttcggcaa gtgctactcc accttctgct ccatcagccc agacactagc
    41101 caattcaact ggtacatcga ttgaggcaca gagttctttt aaggctgcaa tttcagcttc
    41161 tgtatcagat acaaattcgt taatagctac aactgctgga ataccgaact tacggatatt
    41221 ttcaacgtgg cgtttcaagt tagcaaaacc tgcacgaact gcatctacat tttcttcagt
    41281 cagagcgtct ttagccacac caccattcat cttaagggca cgaagggttg cgacaataac
    41341 aactgcatct ggagatgttg gcaagtttgg tgtcttgata tcaaggaatt tctcagcacc
    41401 aaggtccgca ccaaaaccag cttcagtaac agtgtaatca gccaagtgaa gggctgttgt
    41461 cgtcgccaaa acagagttac agccatgagc gatattggca aatggaccac cgtgtacaaa
    41521 ggcaggtgta ccgtaaattg tctgaaccaa gtttggctta atagcatcct tcaaaatcaa
    41581 agccaaggca ccctcaacct gcaaatcacc tacagaaaca ggcgtacggt catagcgata
    41641 accaataacg atattcgcca aacgacgttt caagtcctcg atgtccgttg ccaagcaaag
    41701 aattgccatg atttctgaag caactgtaat atcaaaacca tcctcacgtg gaataccgtt
    41761 tagaggacca ccaagaccaa cagtcacatg gcggagcgca cggtcgttca agtccacaac
    41821 gcgtttccag aggatacgac gttgatcaat tcccagctca ttcccttggt gcaagtggtt
    41881 gtcaatcaag gcagaaaggg cattgttggc agttgtaata gcatgcatat ctccagtaaa
    41941 gtggaggttg atgtcttcca ttggcagaac ttgtgcatac ccaccaccag cagcaccacc
    42001 cttgatcccc atgactggac caagagacgg ttcgcggata gcaatcatgg ttttcttgcc
    42061 aatcttgttc aaggcatccg caagaccaat ggtaagcgtc gactttcctt cacctgcagg
    42121 tgttgggttg atggcagtaa ccaagatcaa tttaccaact ggattgctct caactgcacg
    42181 aattttatca aagctgagtt tagccttgta ctttccgtac aactccaaat cgtcgtaaga
    42241 aataccaagt ttctctacaa catcaacaat tggcttcaac tcaatactct gtgcgatttc
    42301 aatatctgtt ttcattcaaa attcctctaa cctcttatat gataattcat tatatcacaa
    42361 aacaagattt ttaacatcct aaaactctct aaacgttcgt aaatatctct gtttttaagg
    42421 cttttagagt cctttcttaa attttatatg gctttatagt ttgaaactat agtaaatctt
    42481 cgtttttacc aaaaatttat cactttcatt ttacttaccg cttatttttg tgtacaatag
    42541 tgctatgaaa attttagtta catcgggcgg taccagtgaa gctatcgata gcgtccgctc
    42601 tatcactaac cattctacag gtcacttggg gaaaattatc acagagactt tgctttctgc
    42661 agggcatgaa gtttgtttaa ttacgacaaa acgagctctg aagccagagc ctcatcctaa
    42721 cctaagtatt cgagaaatta ccaataccaa ggaccttcta atagaaatgc aagaacgtgt
    42781 tcaggattat caggtcttga tccactcaat ggctgtttct gactacactc ctgtttatat
    42841 gacagggctt gaggaagttc aggctagctc caatctaaaa gaatttttaa gcaagcagaa
    42901 tcatcaggcc aagatttctt caactgatga ggttcaggtt ttgttcctta aaaagacacc
    42961 caaaatcata tccctagtca aggaatggaa tcctactatt catctgattg gtttcaaact
    43021 gctggttgat gttaccgaag atcatctggt tgacattgca cgaaaaagtc ttatcaagaa
    43081 tcaagcagat ttaatcatcg cgaatgacct gactcaaatt tcagcaggtc agcaccgagc
    43141 tatatttgtt gagaaaaatc agcttcaaac agtccagact aaagaagaaa ttgcagaact
    43201 cctccttgaa aaaattcaag cctatcattc ttagaaagga aaactatggc aaacattctc
    43261 ttggctgtaa cgggttcaat cgcctcttat aagtcggcag atttagtcag ttctctaaaa
    43321 aaacaaggcc atcaagtcac tgtcttaatg actcaggctg ctacagagtt tatccaacct
    43381 ttgacactac aggtactctc acagaatcct gtccacttgg atgtcatgaa agaaccctat
    43441 cctgatcagg tcaatcatat cgaacttgga aaaaaagcag atttatttat cgtggtacct
    43501 gcaactgcta acactattgc aaaactagct cacggatttg cggacaacat ggtaaccagt
    43561 acagctctag ccctaccaag tcatattccc aaactaatag ctcctgctat gaatacaaaa
    43621 atgtatgacc atccagtaac tcagaataat ctgaaaacat tagaaaccta cggctatcag
    43681 ctgattgctc ctaaggaatc cctactagct tgtggagacc acggacgagg agctttagct
    43741 gacctcacaa ttattttaga aagaataaag gaaactatcg atgaaaaaac gctctaatat
    43801 tgcacccatt gctatctttt ttgctaccat gctcgtgata cactttctga gctcacttat
    43861 ctttaacctt tttccatttc caatcaaacc gaccattgtt catattcctg tcattattgc
    43921 cagcattatt tatggtccac gagttgggat tacacttgga tttttgatgg gattacttag
    43981 cttgacggtt aacacgatta cgattctacc gacaagctac ctcttctctc ccttcgtacc
    44041 aaacggaaac atctactcag ctatcattgc catcgtccca cgtattttga ttggtttaac
    44101 tccttactta gtctataaac tgatgaaaaa caagactggt ctgattttag ctggagccct
    44161 tggttccttg acaaatacta tctttgtcct tggaggaatc ttcttcctat ttggaaatgt
    44221 ttataatgga aatatccaac ttcttctggc aaccgttatc tcaacaaatt caattgctga
    44281 attggtcatt tctgcaattc taaccctagc cattgttcca cgactacaaa ccttgaaaaa
    44341 ataaaaacaa tctccgcttt caaacctgaa ggtggagatt ttgctctata cagtttcttt
    44401 ttaatgaaat ctttactata gtaaaacgaa ataagaacag gacaaatcga tcaggacagt
    44461 caaatagatt tctaacaatg ttttagaagt agaggtggac tattctagtt tcaatctact
    44521 ataactttta actaaaaaat gatctataaa cccaagtaaa ttcttgcttt attgtctggt
    44581 ttattgtacc atactagtgt atatgcagtt aaaaaggaga ttcttgtgaa tacacggaaa
    44641 aagacacaat ttatgacaat gacagccctt ttaacggcta ttgcgatttt gattccaatt
    44701 gttatgcctt tcaagattgt cattccacct gcttcctata ctttggggag ccacatcgct
    44761 atttttatag ccatgttctt gtcgcccttg atggcagttt ttgtcatcct agcctctagt
    44821 tttggatttt tgatggctgg ctatcccatg gttatagttt ttcgggcttt ttcccatata
    44881 tcttttggtg ctttaggagc tctttaccta caaaaattcc ccgataccct agataaacca
    44941 aaatcttcct gggttttcaa ttttgttttg gctgttgttc atgcccttgc tgaagtatta
    45001 gcctgtgtcc ttttttacgc aacttcgggt accaatgtag aaaacatgtt ctatgttcta
    45061 tttgtactag ttggatttgg cacaattatc catagtatgg tagactatac attagcacta
    45121 gctgtctata aagtgcttcg aaaacgccgt taaaaggaaa agctatgaca aaagatcgca
    45181 aacaagccct gctccaactc ttgaaagaag ctcctaaagc ccttaatggc caaagtttgg
    45241 cggaacattt tcatgtcaca cgtcaggtca ttgtgcagga cattgcaatt ttgagagccg
    45301 atggcgctcc tatcctatcc accaatcgtg gctacatcta taagcaaatt gataccaatc
    45361 cttatgttca caaacttttc aaagtgaaac atgaagttga agaaatcggt caggaactcc
    45421 ttgctattgt cgataatggt gggcatgtcc agaatacttt gattgaccat cccgtttatg
    45481 gagaaattga aaccttgctt aaactgtctt gccgccgaga cgttcaacat tttctagaac
    45541 aagtcgagca ttctgatttt aaacctttat ctgaattgac agatggtgtc cattaccacc
    45601 tagtcgaagc cgaaacacaa caagacctcc actatatcga ggaggccttg gatcagctag
    45661 gttatttagt aaaggattag aaaattttct tttcccaatc gtcttctgta cggcgagggt
    45721 agaaaaattc agatttgtcc gatgcttcca tcatctccat caaaggtagc atatcatagg
    45781 ccagatccaa gtttggaatc tggtcttttt gcacccaaga aacttctcct tcatctgaag
    45841 agcgaagggt accagagaac tcagttgcct tataacaaac gacaatatag cgcccacctg
    45901 tatctagtgg ccaattttta atgccgacaa gttgaggatt ttggatagtc aaccctgttt
    45961 cttcatagat ttcacgaatg acagactctg cgaaagattc gccattttct acatggcctc
    46021 ctggaaaggc ataaccagac cagcgattag tttcaggagc gcgatactgc atcaccacgc
    46081 gctgagcttc gagatcttca atcagacaaa tatttgttaa aatcgttaat tgtgctcgag
    46141 acataaattt actcactttc taatttatta aatttttaga cttgatacca gtaccattag
    46201 cttctacttt ttaaaattat ttagaataga ataccatccg tttttccttt atgggctttc
    46261 caagttcaag tatcttttct tgttcatcaa aagtaaagcc cattttttga tagaaagcaa
    46321 ttgcgcgctt attatctttc aatacccata agaaaatttc agaaaaatga ttaagagcaa
    46381 tcaaagctgc ttttattaac ttttgtgcga taccttttcc ataatagtct tttaaaacat
    46441 ataaagcaat aatttcgcca gcttgaatag tctcatcacg aaagttgcca taactgataa
    46501 aaccaactac cttcatacca tccatcgcaa tcaatgtatt ttctggatac ttttgactaa
    46561 agaatcgaca tctttctaat gtcattgtct cctgaaattc tgcaggcaaa aggccatcat
    46621 aagcctctct ccacgtttgc cagtgaacaa ggggcttacc ttctatctct tcaggagttt
    46681 ccattgattt gataataacc gtcatttgtt ttctcccagt cttctctcaa aataccatat
    46741 ttaatactat caaaatattt accttgataa taacgaactt ttggaatatg agcttctttt
    46801 ttcattctta atttttcagc aagtttcatc ataccaagat tccctgacca agttgtcaaa
    46861 cccagatgct ccaactccaa gtaatcctga aacgtcctat ctatccactg caacatagca
    46921 actttcccaa taccagtgtt ccagaatttt ttatcataaa taccaattcc caattccatc
    46981 catcttgttt gtttacatac ccaataacgc gaaacagtcc caactagttt atcatcaaca
    47041 aaaataccaa ggcgatttga gttgcttaaa atggattctg atttttgtag ttcgaattct
    47101 ttaaaatttg aaaaatactg ataatcatca taatagggag catcatactg tttccaaact
    47161 ggattaagtt gtgaataagc catttcccat aaagacatca aatcttctct ctttaacttt
    47221 cttaaataaa tcatactatt cccctaatcc aaggccttga cttccaacat catatcacgg
    47281 atctgagccg ccagttcaaa gtcaagtact tcgacggctt cttgcatttg tttttctagt
    47341 ttcttgacga gttctttgcg ctcttgtttg ttgaggctat tgatgtcgac ttccttgtcc
    47401 tcttccttag caactgcctt ggtcacagca atcaggtcac ggatttcttt cttgattgtc
    47461 tgtggtacga taccatgctc ttcattatag gccatctgaa ttttccgacg gcgggcagtt
    47521 tcatcgatag cacgttgcat agactgggta accgtgtctg catacatgat gacatggcct
    47581 tcactgttac gagcagcacg tccaatagtc tggatgagtc cacgttcgtt gcgaaggaaa
    47641 ccttccttgt cagcatcgag aatagctacg aggctcactt caggaacgtc aattccttca
    47701 cggagcaggt taattccgac caagacatca aagacaccca agcgcaggtc acggataatc
    47761 tccgtccgtt ccaaggtctt gatatccgag tgcatgtact taaccttgat acccatttcc
    47821 ttgaagtagt cggtcaagtc ctctgccatt ttcttggtca aagttgtgat aaaggtacgc
    47881 tcattttttt caacgcgggc attgatttca cccaagaggt catcaatctg tcccatagtc
    47941 ggacggactt ccacctctgg atccaagagt cccgttggac gaatgatttg ctcaatcact
    48001 gtctcggtct gttcattttc atagtcacca ggtgtcgctg aaacgtaaac aatctgatga
    48061 acgtgactct caaactcctc ccgacggaga ggacgattgt ccaaagcaga cggcaaacgg
    48121 aaaccataat taaccagcat ttctttacgc gaacggtctc cattgtacat gcccttgatt
    48181 tgccctatgg tcatatgact ctcgtcaatc ataatcaaga aatcatctgg gaagaagtcg
    48241 agaagcgtat aaggaggctc tccttcgctc cgtccatcca tgtggcgaga ataattttca
    48301 accccattgg tatagcccat ctcacgcaac atttcgatat catactctgt ccgctgtttc
    48361 aaacgctggg cttcaagcag tttaccttcc ttttcaaaga cagctaattg ttcttccaac
    48421 tcggcctgaa tctttgcaat ggcaacttcc atgtggtcgt cattggtcac aaagtgtgtc
    48481 gctgggaaaa tcgctaaatg atccacttct cccaacacct gacctgtcag agcctcaact
    48541 tcacgaatac ggtcaatttc gtctccaaaa aattctactc gaaaggcatg ttcatctcgg
    48601 gaagctggga aaatctctac cacatcccca cgaacgcgaa atcttccgcg ttggaaatca
    48661 atatcattgc gttcaaactg aatatcgacc aagtcattca agagtttatc acgagaaatc
    48721 tctagaccag gacggagact aacgacacta tcagcgtatt ccttgggcga acccaaacca
    48781 tagatacaag agactgaggc cacgacaata acatcattac gctccaaaag ggctgaggta
    48841 gctgagtggc gaagcttgtc aatctcgtca ttgacagaac tatccttctc aatataggta
    48901 tcgctagaag ggacataggc ctctggctgg taataatcat agtaggatac gaaatactca
    48961 actgcatttt cagggaaaaa ttccttaaac tccccataga gctgaccagc cagagtttta
    49021 ttgtgggcaa taaccagagt tggtttattg actttagaaa tgacctgact catagtatag
    49081 gtcttccctg ttccagtcgc ccccatcaga atctgagctt tttctccccc ctcaatgtta
    49141 tccaccaact gctcgatagc ttggggttga tctcctgatg gttgatattt tgatactagt
    49201 ttaaattgat tatctgtaat gtgattgatc ataagaatcc tctctccatg tgctattcct
    49261 attttagcat acttatagta ttttcacgaa gaaaaggacg gaccgaagtc acatcctttc
    49321 attttctttc tttaatttat tagcaagata gacaatcagc agtagtaata ccagacttgt
    49381 cataatggaa ccttctatgc caaaagaacc acctgataac caatcttgat tgccttgtgg
    49441 taaaaaggtc atcagagacg ttcctgacgg ttgaccacta actaaaatcc caaagagatt
    49501 accctgagca aaattccaag caccatgaat acctgcaaca ccccaaactg tatcagtttt
    49561 gagaaggtaa agagccatgg caactccgaa taaaaagaga tttactagag atagaggggt
    49621 gaggccagaa ttgcccatat gaagcagggt aaagaacagg ctagatataa gaatagctag
    49681 ttttagattg gttcttgagg ccaattgagg aagtagccaa gcacgggcca ccacttcttc
    49741 tgctgtcccc tgtaaaatcc aaaatgggat agtaaagacg acaaaggcaa gagaataagg
    49801 attcaagtga atggattcca aacgatattg acctaagacc accaaaccta acaaggtcag
    49861 aagaaaaagt gccagaccta gactaaatcc tttcagaaga ttgctgaggc aattctctct
    49921 ataaaatccc aaggttcgaa taggtctttt ctcaactttt cttgtccatc tgaacacagt
    49981 gttaagaata aaaccaaagg ccagtaatcc taaaattaaa cgaaagtcac ttgttttatc
    50041 cgtcaagctc tgatgcaagg tctgcaagta ggttgcaaga ttttgaccag cctctccaaa
    50101 atttctagca agtccgatga gagctaacaa gccaatacca tacaaagtaa aagccacaaa
    50161 ctctcctatg aagacaaaaa caatggctaa caaggggctt gtgtaaatgt ttaaactcat
    50221 ttttgaagct tggaagtctt taaatattct tttgttcttc atatccccgt cctcttttct
    50281 tctatatata ctattattat agcacttttt aatagcaatt caagaaaagg aaaaaatcaa
    50341 tgttatattt tctgacacga aaaatataaa aatttgcctt tttttacttt ttctgatata
    50401 atgagagaat attcggaaaa ggagactaaa aatgaagaaa aaatttctag catttttgct
    50461 aattttattc ccaattttct cattaggtat tgccaaagca gaaacgatta agattgtttc
    50521 tgataccgcc tatgcacctt ttgagtttaa agattcagat caaacttata aaggaattga
    50581 tgttgacatt attaacaaag tcgctgagat taaaggctgg aacattcaga tgtcctatcc
    50641 tggatttgac gcagcagtca atgcggttca agctgggcaa gccgacgcta tcatggcagg
    50701 gatgacaaag actaaagaac gtgaaaaagt cttcaccatg tctgatactt actatgatac
    50761 aaaagttgtc attgctacta caaagtcaca caaaattagc aagtacgacc aattaactgg
    50821 caaaaccgtt ggtgttaaaa acggaactgc cgctcaacgt ttccttgaaa caatcaaaga
    50881 taaatacggc tttactatta aaacatttga cactggtgat ttaatgaaca acagcttgag
    50941 tgctggtgcc atcgatgcca tgatggatga caaacctgtt atcgaatatg ccattaacca
    51001 aggtcaagac ctccatattg aaatggatgg tgaagctgta ggaagttttg ctttcggtgt
    51061 gaaaaaagga agtaaatacg agcacctggt tactgaattt aaccaagcct tggctgaaat
    51121 gaaaaaagat ggtagtcttg ataaaattat caagaaatgg actgcttcat catcttcagc
    51181 agtgccaact acaactactc tcgcaggatt aaaagctatt cctgttaagg ctaaatatat
    51241 cattgccagc gattcttctt ttgcaccttt tgttttccaa aattcaagca atcaatacac
    51301 tggtattgat atggaattga ttaaggcaat cgctaaagac caaggttttg aaattgaaat
    51361 caccaaccct ggttttgatg ctgctatcag tgctgtccaa gctggtcaag ccgatggtat
    51421 catcgctggt atgtctgtca cagatgctcg taaggcaact tttgacttct cagaatcata
    51481 ctacactgct aataccattc ttggtgtcaa agaatcaagt aatattgctt cttatgaaga
    51541 tctaaaagga aagacagtcg gtgttaaaaa cggaactgct tctcaaacct tcctaacaga
    51601 aaatcaaagc aaatacggct acaaaatcaa aacctttgct gatggttctt caatgtatga
    51661 cagtttaaac actggtgcca ttgatgccgt tatggatgat gaacctgttc tcaaatattc
    51721 tatcagccaa ggtcaaaaat tgaaaactcc aatctctgga actccaatcg gtgaaacagc
    51781 ctttgccgtt aaaaaaggag caaatccaga actgattgaa atgttcaaca acggacttgc
    51841 aaaccttaaa gcaaacggtg aattccaaaa gattcttgac aaatacctag ctagcgaatc
    51901 ttcaactgct tcaacaagta ctgttgacga aacaacgctc tggggcttgc ttcaaaacaa
    51961 ctacaaacaa ctccttagcg gtcttggtat cactcttgct ctagctctta tctcatttgc
    52021 tattgccatt gtcatcggaa ttatcttcgg tatgtttagc gttagcccat acaaatctct
    52081 tcgcgtcatc tctgagattt tcgttgacgt tattcgtggt attccattga tgattcttgc
    52141 agccttcatc ttctggggaa ttccaaactt catcgagtct atcacaggcc aacaaagccc
    52201 aattaacgac tttgtagctg gaaccattgc cctctcactc aatgcggctg cttatatcgc
    52261 tgaaatcgtt cgtggtggta ttcaggccgt tccagttggc caaatggaag ccagccgaag
    52321 cttgggtatc tcttatggaa aaaccatgcg taagattatc ttgccacaag caactaaatt
    52381 gatgttgcca aactttgtca accaattcgt tatcgctctt aaagatacaa ctatcgtatc
    52441 tgctatcggt ttggttgaac tcttccaaac tggtaagatt atcattgctc gtaactacca
    52501 aagtttcaag atgtatgcaa tccttgctat cttctatctt gtaattatca cacttttgac
    52561 tagactagcg aaacgcttag aaaagaggat tcgttaatgg caaaattaaa aattgatgta
    52621 aatgatttac acaagcacta tggaaaaaat gaagtcctaa aaggaattac gactaagttc
    52681 tatgaaggag atgttgtttg tatcatcggt ccttcaggtt ctggtaagtc aactttcctc
    52741 cgtagcctca atcttttaga agaagtcact agcggtcaca tcactgtgaa cggctatgat
    52801 ttaactgaaa aaacaaccaa tgttgaccac gtccgtgaaa atatcggcat ggtattccaa
    52861 cacttcaacc tcttccctca tatgtctgta ttggacaaca tcacctttgc tcctattgag
    52921 cacaagttga tgactaagga agaagctgag aaattgggaa tggagttgct tgaaaaggtt
    52981 ggactagcag ataaagctaa tgccaatcca gatagcctat caggtggtca aaaacaacgt
    53041 gtggccatag ctcgtggcct agcaatgaat ccagacatca tgctcttcga tgaaccaact
    53101 tctgcccttg accctgagat ggttggagac gtacttaacg ttatgaagga attggctgag
    53161 caaggcatga ccatgattat cgtaacccat gagatgggat ttgctcgtca ggttgccaac
    53221 cgcgttatct ttactgcaga tggcgagttc cttgaagacg gaacacctga ccaaatcttt
    53281 gataacccac aacaccctcg tctgaaagag ttcttagata aggtcttaaa cgtctaaact
    53341 caaactgtaa ggatttcctt gcagtttttc tacctcgtat tggaattttt gatttttcgg
    53401 aaaattatgt tagaattaag tttatgaaat gaggtttcct catacctagc aagactagga
    53461 ataaaaatag aaattaggta gctagatgtc atctaaggtt attgttacaa ttttcggtgc
    53521 gagtggagac ctggctaaac gcaagctcta cccttccctt tttagactat ataaatccgg
    53581 caatctttcc aagcactttg ccgttattgg aactgcccgt agaccttgga gtaaggaata
    53641 ttttgaatct gtagttgtcg agtccatcct tgatttggca gatagtaccg agcaagccca
    53701 agaatttgct agccacttct actatcaaag ccatgatgtc aatgattcgg aacattatat
    53761 tgctttgcgt caattacaag ctgagcttaa tgaaaaatac caagctgaac acaataagct
    53821 cttcttcttg tctatggcac ctcagttctt tggaaccatt gccaaacacc tcaaatctga
    53881 aaacattgtc gatggcaaag gttttgagcg cttgatcgtt gaaaaaccat ttggtacaga
    53941 ttacgcaact gcaaacaagt tgaatgacga actcctagca acatttgacg aagaacaaat
    54001 tttccgtatc gaccattatc ttggtaagga aatgatccaa agcatctttg cagttcgctt
    54061 tgcaaacttg atttttgaaa acgtttggaa caaggatttt atcgacaatg ttcaaattac
    54121 ctttgcggag cgcttgggtg tagaagaacg tggtggctac tatgaccaat ccggtgccct
    54181 ccgtgacatg gtccaaaacc acactctaca acttctttcg ctcctcgcca tggacaaacc
    54241 agcaagcttc acaaaagacg agattcgtgc tgaaaagatt aaggtcttta aaaacctcta
    54301 tcatccaact gatgaagaac tcaaagaaca ctttatccgt gggcaatacc gctctggtaa
    54361 gattgatggc atgaaataca tctcttatcg tagcgagcca aatgtgaatc cagaatcaac
    54421 aactgaaacc tttacatctg gtgccttctt tgtagacagc gatcgattcc gtggtgttcc
    54481 tttctttttc cgtacaggta aacgactgac tgaaaaagga actcatgtca acatcgtctt
    54541 taaacaaatg gattctatct ttggagaacc acttgctcca aatattttga ccatctatat
    54601 tcaaccaaca gaaggcttct ctcttagcct aaatgggaag caagtaggag aagaatttaa
    54661 cttggctcct aactcacttg attaccgtac agatgcgact gcaactggtg cttctccaga
    54721 accatacgaa aaattgattt atgatgtcct aaataacaac tcaactaact ttagccactg
    54781 ggatgaagtt tgtgcgtcat ggaagttgat tgaccgtatt gaaaagctct gggctgaaaa
    54841 tggtgcccca cttcatgact ataaagctgg aagcatggga cctcaagcca gctttgacct
    54901 acttgaaaaa ttcggtgcca aatggacttg gcaaccagat atcacctatc gtcaagatgg
    54961 tcgcttagaa taaaaaaatt tcctgcaagt ttatgccttg caggattttt gcttctgatt
    55021 agattaaacc ttccaagaga cctttcataa agttttctga gttaaactct ccaatatcat
    55081 cgattttttc accaaaacca atcaatttta caggaatatt gagttcttca cgaatggcta
    55141 gaaccacacc tcctcgagca gttccatcaa tcttagtcaa aacaattccc gttaaaggtg
    55201 tgattttcga aaattctttg gcctgtacta gggcattttg acctgttgat gcatcaagtg
    55261 ccaagaaggt ttcatgtggt gcttctggca caacacgttt gataatacga ccaatctttt
    55321 ccaactcagc cataaggtta tccttatttt gcagacgacc agcagtatca atcatgagaa
    55381 tatcgatacc ttcagccacg gcacgttcca taccatcaaa gaccacgctg gctggatcag
    55441 ctttttcagg tccagttact actggaacat ctactcgtcg gccccattca gctagctgag
    55501 ctactgcacc cgcacggaag gtatctgctg caaccagcat gaccttctta ccagcttgtt
    55561 tgtagcggtg ggctagtttt ccgatagaag ttgttttccc aacaccattc acaccaacaa
    55621 agagcataac tgtcaagtta tcttggaagt ggatgctttc atcgtagcta ccatcctttt
    55681 cataaagctc aaccaatttc tcaatgatga cacgacgaag tgcatcaggt ttcttggcat
    55741 tttcaagctt ggcttcgtaa cgtagttcct ccgttaagtt agaagcgact tggacaccaa
    55801 catcactcat aatcagcagt tcttccagtt cctcgaaaaa ttcttcgtca acagagcgga
    55861 agttagcaaa gaaggcattc aagcgggcac cgaaacctgt acgagttttc ttaagactgc
    55921 ggtcatattt ttcctgaacg gtttcttctg cttgaggcct ttctggttca agaacttcag
    55981 aattattttc ttctatagtc tctagaaact cagtattccc ttcttctgag tgtggaaatt
    56041 cttcgacttc tttttgagaa acttctacaa ctggctctaa atccagactt tcttcaactg
    56101 tgtcttggat ttcctcttct tggaacacag cttgttcaac aatttcaacc tctgcttctt
    56161 cctgagaaac ttcctcaact tctgtgaagg taggatcaac atcttcagac aaatcaagat
    56221 tttccagagc ttcttttaca acttcttcga ttttaggttc ttcttttttt ccgaatagac
    56281 ggtcaaacaa tcccatatct tagttctcct ttagcacata ttcttcgata gcccaggcga
    56341 cagcttcctc atcgttggtc atcggcgtca ctacatttgc ggctgccttt acttcaggaa
    56401 cagcgttttg catagcaaca ccaagacctg cccattcaat catagagagg tcattggcct
    56461 cgtcaccaca agccatcact tgactttggt cgattccaag atggctgatt agttttgcca
    56521 aacctgttgc tttatgaaca ttctttggtg accattctag caacatttca cgtgatttaa
    56581 agatttcata ttggtcaaac aattctggag aaatcttctg aatggctgca tccaagggtt
    56641 cttgagcaaa ggcagtcacg catttgttgt aggtcatttg actagataag tcttcaaagt
    56701 ccactggaac aaaggtcaaa gctggattga atttggcata aagactttct tggtccgatt
    56761 ggatttgata aactgttcct tctgagatgg catcaagagg cagtgataat ttctctgttt
    56821 cttcatacaa acgtgccaca tcatcatatg aaaagactgt tttatcaagg atttctcctg
    56881 tatttttctg aactaatcca ccattaaaag taatggtata ctcatcttcc tgaccgtcag
    56941 tccctaactc atggagaaag aaatccatgg cttttaaggg acgaccagtt gtcaatacga
    57001 ccttgatacc acgatcacgc gcagctttca aggtttcctt ggtacgatcc gtcagccttt
    57061 tatcagtagt cagcaaggtc ccgtccaagt ccaatgcaat caattttata tctgccatta
    57121 taagccctcc atataagcta taaccgaccg ttccttatgg tgaccaatca cagtctttgc
    57181 taattctaaa atttcaggtc gtgcattttc aggagctaca ggatgtccca caacctgcat
    57241 catatgtaag tcattaagat tgtctccaaa agccatgacc tgatccattg tgataccaag
    57301 ttttttagct aattcaacaa tagctacacc cttatcgaca tagtccagaa caatatcaat
    57361 agattcaaag ccagttgtca tggccttaac accagggaca tgttcattaa cccaagcttc
    57421 accagcttct agcgtttctt ctgtgaagtt ggttgtaaat ttgaaaatgt catctgtgat
    57481 atcttccaaa ctcgctactt tttggatatt ttcattataa tgctgactca ctttcaaata
    57541 ggtctcatca accgtatcta gaacatatga acccttctta cccgtcaaga gcagtttatt
    57601 gatatctaca taaggtgacg ttttcagctt ttcaaaagtt gccagataaa agtcacgaga
    57661 catagtcgct tcatacaagt cctgaccttg atactctacc aaactgccat tttccgcgat
    57721 gaaaataatg tcatcacgaa catcagcaaa taatttttcc agagacagaa atccccgacc
    57781 cgaagccacc gcaaagtaaa tccctttttc cttgtaggaa gccaagagag acttgagacg
    57841 atccatatca aagcgtccat tcccatctag gaaggttccg tccatatccg ttgctactag
    57901 tttaattgtc atccttcaat actttctaaa tcttttaact taactgaaac aatctttgaa
    57961 acacccgatt cttgcatggt cactccatag atggaatcag ccgctgccat ggttccctta
    58021 cggtgggtta caacgataaa ctggctgtcc ttgtcaaagc ggttgaggta atccccaaaa
    58081 cgtttaacat tggcttcatc cagcgcagct tccacctcat ccaagatgac aaaaggaatg
    58141 gtcttgacac gaataatgga gaaaagcaag gcaagagccg atagagcttt ttcaccacca
    58201 ctcatgaggt taagcgactg gattttctta cctggaggtt gaacagaaat ctccacacca
    58261 gctgttaaaa ggtcgccctc agtcaatatc aagtctgcct gacctccgcc aaacatctgc
    58321 ttgaaggtca ctttaaagga ctcacgaata gcttcaaagg ttgatttaaa gcgttccttg
    58381 acctcatcat tcatctctgt aatggtttca aggagcagat ttttcgctga caaaatatca
    58441 tctcgctgac tatttagaaa gtccagacgg ttgtaaactt cttcgtactg gtcaatagct
    58501 tccaagttga caggtcccaa tgagcgaata gccttctcta aatcctgcac ctcttgctct
    58561 gccagattga ggttttccaa ttcatgtgcc ttttctagtg cttcagtata gctaatctgg
    58621 tactggtctg ttaattgatt ttgtagatgg cgcaagcgct cgctgacctt ttctttcttg
    58681 gcttcagcac gtgtttgctt gcgaatccac tcctcattct gctggcgagc ttgatccaag
    58741 tgactggcaa tatcatccag ttgaccttct atatcatcca actcaaactg cttgcgaatc
    58801 aaaccttgtt ggagatttgt tttctgagtt ttggattctt ccgcctgttg actgagcaat
    58861 tctgtatcaa ccttctcaag attgtcaact ttttcttgga gcatgcgctg aatttcttct
    58921 tgttcgatat taagattgtc caattccttg cctaaacgct caatatcagc tacttcataa
    58981 cgtttttgcc cttgcagttc tgtcttaagc aagcgagctt gcgccacctc ttcctgcaaa
    59041 ttttgatagc gttcttggat ggcgttttta ttagacttaa tttcttcaat ctcagcttcc
    59101 agattttgct tttcactggc gatagtagca aggctctctt gacatttttc cttatccgct
    59161 tgccaatctc cctcagaaag acgatctatt tcctcttctt ggagtttcca aagagtttcc
    59221 agttcttcaa cttgctgact agtttgctga taagcgaggg acaagccttg ctcctgaata
    59281 cgtgcctgct ctccttgaga tttgatggct tctaatcttt ctgtcaatgc agccatctgg
    59341 tcttgcaagg tcttcaaagc cgcttcttct gaacccaagc ttgcttcatc tgcagcaatt
    59401 tctttttgta attgctccag ttctggcttg atgaaaatac tgttattttg gcgattggca
    59461 ccacccgcat aggaaccacc cgtgcgtaat tctgtcccat ccaatgtcac catacgaacc
    59521 tgataacgaa cttgtcgagc agcttcacgc gcatgttcta cggtatcaaa gatagccgtc
    59581 gtagctagca agttcttgaa aatggcttcc agtctagtat caaaagtcac caactcatct
    59641 gccatcccaa ggaaacctgg gcttacagcg atagcatctt ggttctgact agaaatcgta
    59701 cgcgccttaa tagtggtcaa aggaagaaag gttgcacgac cgactctgtt tcgtttgagg
    59761 aaatcaatag ctttggttgc cgactcttca tcttctacga tgatatgctg gctacttgcc
    59821 cctaaggcaa tctctagggc agtttgataa taaacatcaa aggtcagatg ctcactgact
    59881 gcaccaataa tcccacctag gcgatctttt tcttggagaa cactcttaac acctgcataa
    59941 aagttactat gatttctcag gatattttcc aaactttgag ctctggcctg cttgtttttg
    60001 agactatcca gacggtcaaa gagttgactt tgttgagctt gataggaagt tttctgctcc
    60061 tcttgctcct tggcaatagc ttgatagtca gccaataatt tctgaacctg caccttggca
    60121 gtttcaagct cgtctttttg ctgactagcc ttctctttag ctgtagctaa ttgctctttc
    60181 agcttttcta gttgatctgc ttgtttttga gaaagctgac gactattttc caactcattc
    60241 tcaatacggg tcaactggtt tgagacatcc gcttcttctt gtaaaagagc tacaaagcgt
    60301 tcacgtaaga gctcaatcat ctgatcagga tcgtctgaga aagccagcaa ttcagcttct
    60361 aaacgattga gtttttgatt attttggact agatttccct ctaacagagc taaagagctt
    60421 tctttatcat acttttcttt gctgagtgaa tttctcttat cctccaaagc agccaaacga
    60481 gcttgtgcct cctgttgatt cagggccact tgctcggact ccagtttcga tagggctaat
    60541 tttctttcta aatcactaat cagactagtc aagtccatca aactgccttg gtctttggcc
    60601 atttcagcct gtaaatcttg gcgttgcttt ttaagagttt gattttcttc ttctaatttt
    60661 tcacgctttt ggtaataact catcaagagt tcttgaacct gagccaactc ttcttctgtc
    60721 gactctagtt ctgccttatt ttccttgatt tgagcaacca gaacgtctaa ataaatagcc
    60781 ttacgttgtc cttccaagtc taaaaactta cgggcattct cagcttgctt ctcaagaggc
    60841 ttgatttgat tatccaactc gtagataatg tcctctaagc ggtccagatt atcctgagtt
    60901 tgctgcagtt tactctcggt ttcttttctg cgagtcttgt attttaaaac tccagcagct
    60961 tcttcaaaaa tagctcgtcg ttcctcaggc ttggaattaa aaatctcctc aaccttccct
    61021 tgggaaataa tagagaagga atctcgtccc aatccagtat ccaagaagag gtcatgaata
    61081 tcacgcagac ggactttctt gccgtcaatc ttgtattcgc tatctccact acgatagata
    61141 tggcgttcca ccctgatttc ttgacctgca tccttgataa atccgtcatg attatccaga
    61201 gtcacaacta cagaagcata attgagcggt ttgcgacttt ctgttccagc aaagatgaca
    61261 tccggcatct tgcccccacg gagactcttg acactagact cccccaaagc ccaacgcaga
    61321 ctttctgtaa tattggactt tccagatcca ttgggtccaa caactgccgt cacaccttgg
    61381 tcaaaaacga ccttggtctt atcagcaaaa gacttgaacc cctgaatttc gatttccttt
    61441 aaatacatga atccagccct ttctcaacgg catttttggc agcttcctgc tctgctaatt
    61501 tcttagaacg accttggcct tgaccgatgc tcttaccttc aacaagaact tctacatcaa
    61561 agaccttatc gtgagcaggc cctgtttcag aaatcacttg ataacgaata gccacatcac
    61621 cattgacctg aagcaactct tggagatggg ttttatagtc tgtaatcatc tcaaattcgc
    61681 ctgcttctac cttaggaatc ataacttggt agataaattc cttgaccttt gccacatcct
    61741 tatccaaaag aagggcacca agaaaggctt caaaggcatc accaagaatg gtgtcacgat
    61801 tgcgaccacc agatttttct tcccctttac ccaacttgat aaactggtca aactggcaat
    61861 cacgcgcaaa accagctaaa ctctcctcac ggacaatcat agcacggagt tttgataggt
    61921 caccttcagg ctttttagga tattttttat atagatattc tgaaatcaat aactgtagaa
    61981 cagcgtctcc taaaaattcc aagcgttcat tgtgtgaaat ttttaagagg cggtgctcat
    62041 tggcataact cgtatgagta aaggcagttt ccagtaactt tttgtctgca aattcgattt
    62101 caaaatgatt ctttagtaca gtttgtaatt ctttcatacc aacttctttc taactgataa
    62161 tagtcctttt tattatatca aaaaaagccc cctgagtcac tctaaaacgg gactggaaag
    62221 catttgggaa ttctttagac agagattctc agttttagcg gcaaatttgg gtcaggataa
    62281 agaaaaaagc cctattaaag gctttttagg atgtttacat ccaccctgag ggaatcgaac
    62341 ccccatctca agaaccggaa tcttacgtga tatccattac actaagggtg gaaacttgtt
    62401 ttattataac agaaatttgc tctaataaca agttttttgg tcaaagaccc cgtcttagtg
    62461 ggaagcatcc ccattccaga tggagttttt cacgatcaca taatcaacgt gtttaaggtc
    62521 agcaacctga cgtccacctg cataagaaat agcactttga aggtcttgtt ccatctcagt
    62581 taaagtgtct tgcagatgac ctttagcagg aagcaagata cgtttgcctt ccacattttt
    62641 gtaagcacct ttctgatatt gtgaggctga accataatat tctttgaact gttcaccatc
    62701 gacttcaatc gttttccctg gactttcaat gtgtcctgca aagagggaac caatcatgat
    62761 catgctagca ccgaagcgga tagacttggc aatatcaccg tgagtacgaa ttcctccatc
    62821 agcgataatc ggtttacgcg cagccttggc acaccagcgt agagcagcca actgccaacc
    62881 acctgtacca aaaccagtct taaccttggt gatacaaacc ttaccaggac cgattccgac
    62941 cttagtagca tctgcaccag cattttccaa ttcacgcaca gcttctggtg ttcccacatt
    63001 tccagcaatg acaaaggtat ctggcaattc tttcttgatg tgttgaatca tagaaatcac
    63061 gctatccgca tgaccatgag caatatcaat agtgatatac tcaggagcat cagccttgag
    63121 ctggctaaca aaatcatact cataatcctt aacaccgaca gatatggaag caatgagccc
    63181 ttgatcgtgc attcgtttaa taaaaggaat gcgtcctgcc tcatcaaaac ggtgcataat
    63241 gtagaagtaa ccacctttag ccagttgctc tgctacattt tcatccaaaa tcgtctgcat
    63301 attcgctggc acaacaggta gtttaaaggt gtgatttcct aaagtgacac ttgtatccgc
    63361 ttctgcacgg cttttaatga cacatttatt tggaatcaat tgaatatctt cgtaatcaaa
    63421 aattggaaat tcatttaaca tatcgatgtc tcgtttcttt tgtaatgacc tacctatgct
    63481 ctcgcatcac tacgcctttt ccgacgtttc cttaatttat tataaaccaa agtacagttt
    63541 ttgtcaaatt attttatgaa ttaaaatata ttgttcggat tttgcttgtg ttaaaaataa
    63601 aagaaagagg ggaaattatt ttctccccac ttcttcatca ataatcgctt taaaattttc
    63661 ttctgaattt tccatcattt tacaaaatgc actataagat gaagacttct gaggaatttg
    63721 gatagaccat ttcttcaaca aagctccata acctgctagg tttcctatct cattatcaat
    63781 gaccttgtcc ttgctcggaa aaacaagtcc agccttctca gcttttaaaa tataagaata
    63841 ggaaatcagc tggaataagt cctcacggtt gattcctttt tcagtcaatt ccagtttttt
    63901 atattttgca tctagaacaa tctttcgttc tctgtcataa aaatctggat atacttttcg
    63961 tttcccaaca gaaaatactg aaattccatc cgtcttatcc ttatttctgg gatgtacaaa
    64021 accttttggc aacaaggtgt aaacatactc ttcccaaagc caggcaacat caaagagaat
    64081 accatagatt ttttgatctt gataccctaa accgtgcttt tcttggttta ggatcatcag
    64141 acaaagttct tgtaagtttc tgtactcgtg aaagtatgca tgacgtatag gtttagattg
    64201 atttctccga gtaatcttag cacgatcagc tagtttataa gagggcgtta cacgcacgat
    64261 ttcagatacg ttttcacgac tagttgagag attatctagt accccttgac caatgctttt
    64321 ctgattctta atgtattcaa tagtgtgacg gaccaactgc atgaggggat tatcataggt
    64381 gaactctctc gttgtgtagg caatatttcc cgtgaaagga agatttttct tgagatggtt
    64441 tcttacaaca atcactccct taacattact gtcgttatga gaaaatcgat gatattcctt
    64501 ataaagacct tttcgaatag cagcttgtag atacttgggg aagagataca tcaaaagttg
    64561 ataaagcctc tcttcacgag acaaagcaac atctaaacta gtgagattga tataaagaac
    64621 cttgtttaag agataatgca aaaaatggtc attactctca tcagaaaatc gtgaggaaat
    64681 cgttaatctt tcctgaccat atccaagaaa accaatcacg ttccctgtct tgattttctg
    64741 attgactgtt tcaaaaatct tttgatcctt atccaaatca ggagtatgag tcaaatcatt
    64801 tggaaaaatg aaaatacgtt catcttggga tagactttcc aaggttctgt ctaaaagaag
    64861 attgcttagt ttaggatatt cttcaacaaa tttttcttta ataatcttgt gttgattatc
    64921 agtaatccgc atcatcgttt tcatcacctt cattgtcatc agctactgcc tgatcttttt
    64981 gctcattatt tgtcagttca aatgcttttt tcaaagtttc caaagtttca acctcatcat
    65041 aagaacctcg caagtagtct tctaggagag gcttaatata atcagaccag agtaattcat
    65101 agtcaaaatc tacatccttc aacttaagaa aataacttgg tccaatatga taatgactgt
    65161 ttaattcctg aacattttcg atagcagcgt tcaagtttct tagacgaatt tttgcttctt
    65221 ctgcatggat attcagctct ttatccaaca tgccaacttg accctcggca gtaacttcaa
    65281 caaaacgaaa acgacgacgc atagcaaaat caaaggtatc cactgaacga tcaatatcat
    65341 tcatagttcc gatgatgtaa acattttcgg ggatatagaa cttttcatca gtttcgtgta
    65401 gatttgcata ttgggtagaa acacttcctt tttcaccacg atagccaggg tcgatagaaa
    65461 aaaagagttc gccaaaaatc ttagaaatct ccccacgatt gatctcatcg atgatgaaaa
    65521 caaatttctt gtctgtttca acctcttctg gagaaatata gtctttcaaa ccaaatctct
    65581 ttctcaatgt ttctaggaca gtttttccac cacttttgta gtattcttgc ttattataat
    65641 ttttatcttt atacaactcg taaacatatt tgctaggtag tgaccatcct ggaacaccac
    65701 tatcataatt tactgacaaa ttttgtctac tattaacaga taagtaagat gtttttgtta
    65761 tatattcttt ttcttcagca acatttatat attctaagta agaatcccaa gcctcatcaa
    65821 aattatcttg tcctccaatc aattgggttt cttttgcttt ctgacaaaaa tctttaaaaa
    65881 taccgtcctg tagcctaaac tcaatagctc catccccatt tgatactggt cttaaacctt
    65941 ctacaaaatc cgtataatca taggatgggt gaaattgtac aaatccgatt tggtcttcgt
    66001 taccatccgt taattctttg gcaatttctt tagcaagata agtctttcct gtgccaggag
    66061 caccacgaag gataaggttt ggagacttta atagagattg agttaattga tgactaaaat
    66121 tgtttgatga atccattgta ctattgtctt ccttattttc cataaaaagc ttagaatact
    66181 caaaaagcat agttcctaat ttcgatggct ccaactcagg ataagttttg gacaccagtt
    66241 caattatttt atgattttgc agataaggtc caccttgatt tgtctgagaa acaaagtggt
    66301 tccaaaattc tttctgacta ttaatattta caccaaagaa aggatctccc tcagtataga
    66361 tacaaagtaa ttttgtcacc atagcagaac gaccaataaa ttcatttgtt gatcttttca
    66421 tatcaaaaat aggattttca aagttaaaac gaataccttc tttgataatt tcataca
//
LOCUS       DBJKQU010000006        64795 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.006, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000006 DBJKQU010000000
VERSION     DBJKQU010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 64795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64795
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.006"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            144..800
                     /locus_tag="ACSUUC_000424"
     CDS             144..800
                     /locus_tag="ACSUUC_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HHQ8053709.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            790..1113
                     /locus_tag="ACSUUC_000425"
     CDS             790..1113
                     /locus_tag="ACSUUC_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HHQ8053710.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            1217..2047
                     /locus_tag="ACSUUC_000426"
     CDS             1217..2047
                     /locus_tag="ACSUUC_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HHQ8053711.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2201..3055
                     /locus_tag="ACSUUC_000427"
     CDS             2201..3055
                     /locus_tag="ACSUUC_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HHQ8053712.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3155..4528
                     /locus_tag="ACSUUC_000428"
     CDS             3155..4528
                     /locus_tag="ACSUUC_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHQ8053713.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVSMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4521..5582
                     /locus_tag="ACSUUC_000429"
     CDS             4521..5582
                     /locus_tag="ACSUUC_000429"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053714.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            5584..6276
                     /locus_tag="ACSUUC_000430"
     CDS             5584..6276
                     /locus_tag="ACSUUC_000430"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HHQ8053715.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIVIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6306..6875)
                     /locus_tag="ACSUUC_000431"
     CDS             complement(6306..6875)
                     /locus_tag="ACSUUC_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HHQ8053716.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPTPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7010..7624
                     /locus_tag="ACSUUC_000432"
     CDS             7010..7624
                     /locus_tag="ACSUUC_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HHQ8053717.1"
                     /translation="MGRFLDFVFNRFFLGMIATALFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7602..9272
                     /locus_tag="ACSUUC_000433"
     CDS             7602..9272
                     /locus_tag="ACSUUC_000433"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHQ8053718.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9284..10570
                     /locus_tag="ACSUUC_000434"
     CDS             9284..10570
                     /locus_tag="ACSUUC_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHQ8053719.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10622..11155
                     /locus_tag="ACSUUC_000435"
     CDS             10622..11155
                     /locus_tag="ACSUUC_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8053720.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11233..11703
                     /gene="nrdI"
                     /locus_tag="ACSUUC_000436"
     CDS             11233..11703
                     /gene="nrdI"
                     /locus_tag="ACSUUC_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HHQ8053721.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKRIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11996..13258)
                     /locus_tag="ACSUUC_000437"
     CDS             complement(11996..13258)
                     /locus_tag="ACSUUC_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HHQ8053722.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIEKAG"
     gene            complement(13568..14026)
                     /locus_tag="ACSUUC_000438"
     CDS             complement(13568..14026)
                     /locus_tag="ACSUUC_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HHQ8053723.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14023..14463)
                     /locus_tag="ACSUUC_000439"
     CDS             complement(14023..14463)
                     /locus_tag="ACSUUC_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HHQ8053724.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14819..16768
                     /gene="mutL"
                     /locus_tag="ACSUUC_000440"
     CDS             14819..16768
                     /gene="mutL"
                     /locus_tag="ACSUUC_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HHQ8053725.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVDQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17093..17560)
                     /gene="ribH"
                     /locus_tag="ACSUUC_000441"
     CDS             complement(17093..17560)
                     /gene="ribH"
                     /locus_tag="ACSUUC_000441"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HHQ8053726.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17561..18766)
                     /locus_tag="ACSUUC_000442"
     CDS             complement(17561..18766)
                     /locus_tag="ACSUUC_000442"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HHQ8053727.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRIDDLIQFSKKHNIPLITIKELQEYRKAYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKIIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18786..19421)
                     /gene="ribE"
                     /locus_tag="ACSUUC_000443"
     CDS             complement(18786..19421)
                     /gene="ribE"
                     /locus_tag="ACSUUC_000443"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HHQ8053728.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19406..20506)
                     /gene="ribD"
                     /locus_tag="ACSUUC_000444"
     CDS             complement(19406..20506)
                     /gene="ribD"
                     /locus_tag="ACSUUC_000444"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HHQ8053729.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGSHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMTMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20640..20754)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            20911..21504
                     /gene="ruvA"
                     /locus_tag="ACSUUC_000445"
     CDS             20911..21504
                     /gene="ruvA"
                     /locus_tag="ACSUUC_000445"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HHQ8053730.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKIAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21514..22077
                     /locus_tag="ACSUUC_000446"
     CDS             21514..22077
                     /locus_tag="ACSUUC_000446"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008725 - DNA-3-methyladenine glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HHQ8053731.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22074..22751
                     /locus_tag="ACSUUC_000447"
     CDS             22074..22751
                     /locus_tag="ACSUUC_000447"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHQ8053732.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(22888..23919)
                     /locus_tag="ACSUUC_000448"
     CDS             complement(22888..23919)
                     /locus_tag="ACSUUC_000448"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 family peptidase"
                     /protein_id="HHQ8053733.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(24174..24857)
                     /locus_tag="ACSUUC_000449"
     CDS             complement(24174..24857)
                     /locus_tag="ACSUUC_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HHQ8053734.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24869..25813)
                     /locus_tag="ACSUUC_000450"
     CDS             complement(24869..25813)
                     /locus_tag="ACSUUC_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HHQ8053735.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            25945..28776
                     /gene="uvrA"
                     /locus_tag="ACSUUC_000451"
     CDS             25945..28776
                     /gene="uvrA"
                     /locus_tag="ACSUUC_000451"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HHQ8053736.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28769..29830
                     /locus_tag="ACSUUC_000452"
     CDS             28769..29830
                     /locus_tag="ACSUUC_000452"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HHQ8053737.1"
                     /translation="MNKRVQAFLVKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLFPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            29962..30360
                     /gene="spx"
                     /locus_tag="ACSUUC_000453"
     CDS             29962..30360
                     /gene="spx"
                     /locus_tag="ACSUUC_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HHQ8053738.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30426..30995
                     /locus_tag="ACSUUC_000454"
     CDS             30426..30995
                     /locus_tag="ACSUUC_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HHQ8053739.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLVGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            31082..31348
                     /locus_tag="ACSUUC_000455"
     CDS             31082..31348
                     /locus_tag="ACSUUC_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HHQ8053740.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31352..31771
                     /gene="ruvX"
                     /locus_tag="ACSUUC_000456"
     CDS             31352..31771
                     /gene="ruvX"
                     /locus_tag="ACSUUC_000456"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HHQ8053741.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31787..32092
                     /locus_tag="ACSUUC_000457"
     CDS             31787..32092
                     /locus_tag="ACSUUC_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HHQ8053742.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32552..33802
                     /locus_tag="ACSUUC_000458"
     CDS             32552..33802
                     /locus_tag="ACSUUC_000458"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HHQ8053743.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33886..34344
                     /locus_tag="ACSUUC_000459"
     CDS             33886..34344
                     /locus_tag="ACSUUC_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HHQ8053744.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPVAQQQVQQPAQQ
                     NTNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESD
                     GDQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            34490..36022
                     /gene="cls"
                     /locus_tag="ACSUUC_000460"
     CDS             34490..36022
                     /gene="cls"
                     /locus_tag="ACSUUC_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HHQ8053745.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            36280..37818
                     /locus_tag="ACSUUC_000461"
     CDS             36280..37818
                     /locus_tag="ACSUUC_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HHQ8053746.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMDVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37938..40145
                     /gene="nrdD"
                     /locus_tag="ACSUUC_000462"
     CDS             37938..40145
                     /gene="nrdD"
                     /locus_tag="ACSUUC_000462"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HHQ8053747.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKGENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            40157..40297
                     /locus_tag="ACSUUC_000463"
     CDS             40157..40297
                     /locus_tag="ACSUUC_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053748.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40341..40847
                     /locus_tag="ACSUUC_000464"
     CDS             40341..40847
                     /locus_tag="ACSUUC_000464"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8053749.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGLWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVKR
                     YWIEVANE"
     gene            40840..41430
                     /gene="nrdG"
                     /locus_tag="ACSUUC_000465"
     CDS             40840..41430
                     /gene="nrdG"
                     /locus_tag="ACSUUC_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HHQ8053750.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41427..42044
                     /locus_tag="ACSUUC_000466"
     CDS             41427..42044
                     /locus_tag="ACSUUC_000466"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase family protein"
                     /protein_id="HHQ8053751.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42311..42619
                     /gene="rpsJ"
                     /locus_tag="ACSUUC_000467"
     CDS             42311..42619
                     /gene="rpsJ"
                     /locus_tag="ACSUUC_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HHQ8053752.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42835..43461
                     /gene="rplC"
                     /locus_tag="ACSUUC_000468"
     CDS             42835..43461
                     /gene="rplC"
                     /locus_tag="ACSUUC_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HHQ8053753.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43486..44109
                     /gene="rplD"
                     /locus_tag="ACSUUC_000469"
     CDS             43486..44109
                     /gene="rplD"
                     /locus_tag="ACSUUC_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HHQ8053754.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            44109..44405
                     /locus_tag="ACSUUC_000470"
     CDS             44109..44405
                     /locus_tag="ACSUUC_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HHQ8053755.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44423..45256
                     /gene="rplB"
                     /locus_tag="ACSUUC_000471"
     CDS             44423..45256
                     /gene="rplB"
                     /locus_tag="ACSUUC_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HHQ8053756.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45360..45641
                     /gene="rpsS"
                     /locus_tag="ACSUUC_000472"
     CDS             45360..45641
                     /gene="rpsS"
                     /locus_tag="ACSUUC_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HHQ8053757.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45653..45997
                     /gene="rplV"
                     /locus_tag="ACSUUC_000473"
     CDS             45653..45997
                     /gene="rplV"
                     /locus_tag="ACSUUC_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HHQ8053758.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            46010..46663
                     /gene="rpsC"
                     /locus_tag="ACSUUC_000474"
     CDS             46010..46663
                     /gene="rpsC"
                     /locus_tag="ACSUUC_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HHQ8053759.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46667..47080
                     /gene="rplP"
                     /locus_tag="ACSUUC_000475"
     CDS             46667..47080
                     /gene="rplP"
                     /locus_tag="ACSUUC_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HHQ8053760.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            47090..47296
                     /gene="rpmC"
                     /locus_tag="ACSUUC_000476"
     CDS             47090..47296
                     /gene="rpmC"
                     /locus_tag="ACSUUC_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HHQ8053761.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47321..47581
                     /gene="rpsQ"
                     /locus_tag="ACSUUC_000477"
     CDS             47321..47581
                     /gene="rpsQ"
                     /locus_tag="ACSUUC_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HHQ8053762.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47607..47975
                     /gene="rplN"
                     /locus_tag="ACSUUC_000478"
     CDS             47607..47975
                     /gene="rplN"
                     /locus_tag="ACSUUC_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HHQ8053763.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            48053..48358
                     /gene="rplX"
                     /locus_tag="ACSUUC_000479"
     CDS             48053..48358
                     /gene="rplX"
                     /locus_tag="ACSUUC_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HHQ8053764.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48382..48924
                     /gene="rplE"
                     /locus_tag="ACSUUC_000480"
     CDS             48382..48924
                     /gene="rplE"
                     /locus_tag="ACSUUC_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HHQ8053765.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48942..49211
                     /gene="rpsN"
                     /locus_tag="ACSUUC_000481"
     CDS             48942..49211
                     /gene="rpsN"
                     /locus_tag="ACSUUC_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HHQ8053766.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49496..49894
                     /gene="rpsH"
                     /locus_tag="ACSUUC_000482"
     CDS             49496..49894
                     /gene="rpsH"
                     /locus_tag="ACSUUC_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HHQ8053767.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            50086..50622
                     /gene="rplF"
                     /locus_tag="ACSUUC_000483"
     CDS             50086..50622
                     /gene="rplF"
                     /locus_tag="ACSUUC_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HHQ8053768.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50706..51062
                     /gene="rplR"
                     /locus_tag="ACSUUC_000484"
     CDS             50706..51062
                     /gene="rplR"
                     /locus_tag="ACSUUC_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HHQ8053769.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            51080..51574
                     /gene="rpsE"
                     /locus_tag="ACSUUC_000485"
     CDS             51080..51574
                     /gene="rpsE"
                     /locus_tag="ACSUUC_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HHQ8053770.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51588..51770
                     /gene="rpmD"
                     /locus_tag="ACSUUC_000486"
     CDS             51588..51770
                     /gene="rpmD"
                     /locus_tag="ACSUUC_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HHQ8053771.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            51915..52355
                     /gene="rplO"
                     /locus_tag="ACSUUC_000487"
     CDS             51915..52355
                     /gene="rplO"
                     /locus_tag="ACSUUC_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HHQ8053772.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52368..53678
                     /gene="secY"
                     /locus_tag="ACSUUC_000488"
     CDS             52368..53678
                     /gene="secY"
                     /locus_tag="ACSUUC_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HHQ8053773.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53829..54467
                     /locus_tag="ACSUUC_000489"
     CDS             53829..54467
                     /locus_tag="ACSUUC_000489"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HHQ8053774.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54584..54802
                     /gene="infA"
                     /locus_tag="ACSUUC_000490"
     CDS             54584..54802
                     /gene="infA"
                     /locus_tag="ACSUUC_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HHQ8053775.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54827..54943
                     /gene="rpmJ"
                     /locus_tag="ACSUUC_000491"
     CDS             54827..54943
                     /gene="rpmJ"
                     /locus_tag="ACSUUC_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HHQ8053776.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54961..55326
                     /gene="rpsM"
                     /locus_tag="ACSUUC_000492"
     CDS             54961..55326
                     /gene="rpsM"
                     /locus_tag="ACSUUC_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HHQ8053777.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55344..55727
                     /gene="rpsK"
                     /locus_tag="ACSUUC_000493"
     CDS             55344..55727
                     /gene="rpsK"
                     /locus_tag="ACSUUC_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HHQ8053778.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55770..56705
                     /locus_tag="ACSUUC_000494"
     CDS             55770..56705
                     /locus_tag="ACSUUC_000494"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HHQ8053779.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56717..57103
                     /gene="rplQ"
                     /locus_tag="ACSUUC_000495"
     CDS             56717..57103
                     /gene="rplQ"
                     /locus_tag="ACSUUC_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HHQ8053780.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57368..57634
                     /locus_tag="ACSUUC_000496"
     CDS             57368..57634
                     /locus_tag="ACSUUC_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HHQ8053781.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57644..58981
                     /locus_tag="ACSUUC_000497"
     CDS             57644..58981
                     /locus_tag="ACSUUC_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HHQ8053782.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59225..59917
                     /locus_tag="ACSUUC_000498"
     CDS             59225..59917
                     /locus_tag="ACSUUC_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HHQ8053783.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(60020..61665)
                     /locus_tag="ACSUUC_000499"
                     /pseudo
     CDS             complement(60020..61665)
                     /locus_tag="ACSUUC_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(61655..62746)
                     /locus_tag="ACSUUC_000500"
                     /pseudo
     CDS             complement(61655..62746)
                     /locus_tag="ACSUUC_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62759..63880)
                     /locus_tag="ACSUUC_000501"
                     /pseudo
     CDS             complement(62759..63880)
                     /locus_tag="ACSUUC_000501"
                     /inference="COORDINATES: protein motif:HMM:NF024808.6"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(64467..>64795)
                     /locus_tag="ACSUUC_000502"
     CDS             complement(64467..>64795)
                     /locus_tag="ACSUUC_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HHQ8053784.1"
                     /translation="KHKKVTGVFNQMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDA
                     EKFATLFNSLNIDQVQLLPFHQFGENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNH
                     HINCYF"
BASE COUNT        19433 a        12140 c        14302 g        18920 t
ORIGIN      
        1 acgaaacaat tgctaaaaca tttatagaaa ttaattttac tttcccaatc gatttgttca
       61 tatcttattt caatccatta tattaagaca atatgaggag aaagatgaaa gaaaaaggat
      121 tttaggaggg ggtgcaggca gtcatgccaa cggctcttgg ttatgtcagt atcggcctgg
      181 cctgtggaat tatcggtgcg ccctatgtga cacctgttga gatgggcttg atgagtctct
      241 ttgtttatgc tgggagtgcc cagtttgcca tgttggcact gattgtggtt caagctcctg
      301 tggcagctat tgctatgacg gtttttctaa tcaacttgcg tctctttttg ttgagtttac
      361 acgcatcgac ttatttccgt cataccagtc tttggtacaa tatcggtatg tctagtatct
      421 tgacagatga gacctatggc gttttgatgg gtgaattggc ccatacagac aaggtaaatc
      481 ctatgtggat gcacggaaac aatcttaaca gctatgtggc ttggtttgtg gggacagtag
      541 tcggaacggc tctgggtggc ctgctaccaa atccagaaat ctttggcttg gattttgccc
      601 tggttgggat gtttattggt atttttgctt cgcaatttca gattatgcaa agacggattc
      661 ctgtccgcaa tctgctcatt atcctagcag ttgttgcggt gtccttcttt ttgctcttga
      721 cagtggtgtc tcagtcacta gctgttctgt ttgcgacgct acttggttgt agcatggggg
      781 tggttttaga tggtcagtaa gtatctttta ttagcagtta ttttctctgg cttggtgact
      841 tggattctcc gtatgattcc cttcatctta gtcaagtata agggcttgcc tgcaatcgtt
      901 gagcgttttt tgaagttctt gcccgtttcc attatctttg ccttgattct ttcaagcgta
      961 gtgacaggta aggttgggag ccttcctcaa attaaatggc tagacttctt agccgtcttt
     1021 ccaacagctt gggtagcctt tcgctaccgc aatctagtcg gtacggttct ctttggagta
     1081 gtcttgattg ccgtcttgcg tttggtcttt taaataagtc ataaagaaaa cttatcacag
     1141 agatagatat catataatgg cgtaattact ttttttctga taagattata aggtattcta
     1201 ttttggagga aatgacatga aaaaaatcgt taaatactca tctcttgcag cccttgctct
     1261 tgttgctgca ggtgtgcttg cggcttgctc aggtggtgct aagaaagaag gacaagcagc
     1321 tagcaagaaa gaaatcatcg ttgcaaccaa tggatcacca aagccattta tctatgaaga
     1381 aaatggcgaa ttgactggtt atgagattga agtcgttcgc gctatcttta aagattctga
     1441 caaatatgat gtcaagtttg aaaagacaga atggtcaggt gtctttgctg gtcttgacgc
     1501 tgaccgttac aatatggctg tcaacaatct tagctacact aaagaacgtg cggagaaata
     1561 cctctatgcc gcaccaattg cccaaaatcc taatgtcctt gtcgtgaaga aagatgactc
     1621 tagtatcaag tctctcgatg atatcggtgg aaaatcgacg gaagtcgttc aagccactac
     1681 atcagctaag cagttagaag catacaatgc tgaacacacg gacaacccaa ctatccttaa
     1741 ctatactaag gcagacttcc aacaaatcat ggtacgtttg agcgatggac aatttgacta
     1801 caagattttt gataaaatcg gtgttgaaac agtgatcaag aaccaaggtt tggacaactt
     1861 gaaagttatc gaacttccaa gcgaccaaca accgtacgtt tacccacttc ttgctcaggg
     1921 tcaagatgag ttgaaatcat ttgtagacaa acgcattaaa gaactctaca aagacggaac
     1981 gcttgaaaaa ttgtctaaac aattcttcgg agatacttat ctaccagcag aggctgatat
     2041 taaataattt cttgaaatca tccattctga gtaagatggg tgatttctca gtttttaggg
     2101 atatagtttt aaactatata tctgattatc taataacaat ttgtgaaatc aaacaaattg
     2161 tgagatacta gtacggtatt atttttaagg agaaagaatc atgaaaatca aaaaatggct
     2221 tggcctagca gcccttgcta cagtcgcagg tttggctctt gcagcttgcg gaaactcaga
     2281 aaagaaagca gacaatgcaa caactatcaa aatcgcaact gttaaccgta gcggttctga
     2341 agaaaaacgt tgggacaaaa tccaagaatt ggttaaaaaa gacggaatta ccttggaatt
     2401 tacagagttc acagactatt cacaaccaaa caaagcaact gctgatggcg aagtagattt
     2461 gaacgctttc caacactata acttcttgaa caactggaac aaagaaaacg gaaaagacct
     2521 tgtagcgatt ggagatactt acatctctcc aatccgcctt tactcaggtt tgaatggaag
     2581 tgccaacaag tacactaaag tagaagacat cccagcaaac ggagaaatcg ctgtaccgaa
     2641 tgacgctaca aacgaaagcc gtgcgcttta cttgcttcaa tcagctggct tgattaaatt
     2701 ggatgtttct ggaactgctc ttgcaacagt tgccaacatc aaagaaaatc caaagaactt
     2761 gaaaatcact gaattggacg ctagccaaac agctcgttca ttgtcatcag ttgacgctgc
     2821 cgttgtaaac aataccttcg ttacagaagc aaaattggac tacaagaaag cacttttcaa
     2881 agaacaagct gatgaaaact caaaacaatg gtacaacatc attgttgcga aaaaagattg
     2941 ggaaacatca cctaaggctg atgctatcaa gaaagtaatc gcagcttacc acacagatga
     3001 cgtgaaaaaa gttatcgaag aatcatcaga cggtttggat caaccagttt ggtaataaga
     3061 aacagggagg tgggagagag aattccacct cttgcttttg tatagagcac ggagtgtaaa
     3121 gaagactatt cgttcataga aaggtagaga gaatatggtt tttcctagcg aacaagaaca
     3181 gattgaaaaa tttgaaaagg atcatgtagc ccagcattat tttgaggttt tacgtacctt
     3241 gatttctaag aaatcagtct ttgcccagca ggttggactc aaggaagtcg caaattatct
     3301 gggtgagatt ttcaagcgtg ttggagctga agtggagatt gatgagagct atacagcgcc
     3361 ctttgtcatg gcacatttca agagttcgcg tccagatgcc aagaccttga ttttctataa
     3421 ccactatgac actgtgccag cggatgggga tcaggtctgg acagaggatc cttttacgct
     3481 ttcggtccgc aatggcttca tgtatgggcg tggggttgat gacgacaagg gtcatatcac
     3541 agctcgcttg agtgctttga gaaaatatat gcagcaccat gatgatttac ctgtcaatat
     3601 cagctttatc atggagggag cggaggaatc ggcttcaaca gacctagata agtatttgga
     3661 aaagcatgca gacaaactcc gtggggcgga tttgttggtc tgggaacaag ggaccaaaaa
     3721 tgccttggaa cagctggaaa tttctggtgg caataagggg attgtgacct ttgatgccaa
     3781 ggtaaaaagc gctgatgtgg atatccactc gagttatggt ggtgttgtgg aatcagctcc
     3841 ttggtatctc ctccaagcct tacagtctct tcgtgctgcg gatggccgta tcttggttga
     3901 aggcttgtac gaagaagtac aagagcccaa tgaacgagaa atggccttgc tagaaactta
     3961 tggtcaacga aacccagagg aagttagtcg gatttatgga ttggagttgc ctctcttaca
     4021 ggaggagcgg atggcctttc taaaacgttt ctttttcgag ccagcgctta atatcgaagg
     4081 aatccagtct ggttatcaag gtcagggtgt taagactatt ttacctgcag aagccagtgc
     4141 caagctagag gttcgtctgg ttccgggtct agaaccgcat gatgttctgg aaaaaattcg
     4201 gaaacaacta gacaaaaatg gctttgataa ggtagaatta tactatacct tgggagagat
     4261 gagctatcga agcgatatga gcgcaccagc cattctcaat gtgatcgagt tggccaagaa
     4321 attctatcca cagggcgttt cagtcttgcc gacgacagcg gggacaggac ctatgcatac
     4381 ggtctttgat gccctagagg tatcaatggt tgcattcggt ctaggaaatg ccaatagccg
     4441 agaccacggt ggagatgaaa atgtgcgaat cgctgattat tacacccata tcgaattagt
     4501 agaggagctg attagaagct atgagtagag atattatcaa gttagatcag atcgatgtga
     4561 cttttcacca aaagaagaga accattacag cggttaagga tgtgaccatt cacatccaag
     4621 aaggggatat ctacggaatc gttggatatt ctggagcagg aaaatcaacc cttgtacggg
     4681 tgattaacct cttgcaaaaa ccatctgcag ggaaaattac cattgacgac gatgtgattt
     4741 ttgatggtaa ggtcaccttg acggcagagc agttgcgtcg taaacgtcaa gatatcggga
     4801 tgattttcca gcattttaac ctgatgagcc aaaagacagc agaggagaat gtagcctttg
     4861 cccttaaaca ctctggactc agcaaggaag aaaagaaggc taaagtagct aagttgttgg
     4921 acttggttgg tttggcagat cgtgctgaaa actacccttc acaactatct ggagggcaaa
     4981 aacagcgtgt ggcaattgcg cgtgccttgg ccaatgatcc aaaaatcttg atttcagacg
     5041 agtcaacttc tgcccttgac cctaagacaa ccaagcagat tttggccttg ttgcaagatt
     5101 tgaaccaaaa attaggcttg actgttgtct tgattacgca tgaaatgcag attgtcaaag
     5161 acattgccaa ccgtgtggcg gttatgcagg atgggcattt gattgaagag ggtagtgtgc
     5221 ttgaaatctt ctcaaaccct aaacaacctt tgactcaaga ctttatctca acagctacag
     5281 gtattgacga agccatggtc aaaatcgaga agcaagaaat cgtggaacac ttgtctgaaa
     5341 acagtctctt ggtgcaactc aagtacgctg gagcttcaac agacgagcca cttttgaatg
     5401 aattgtacaa gcattaccaa gtaatggcta atattctcta tgggaatatc gaaattctcg
     5461 atggtactcc tgttggagaa ttggtggtgg tcttgtcagg tgaaaaagca gcgttggcag
     5521 gtgcccaaga agctattcgc caagcaggtg tacaactaaa agtattgaag ggaggacagt
     5581 aagatggaat cattgattca aacctattta ccaaatgtct ataaaatggg ttgggctggt
     5641 caggcaggct ggggaacggc tatctactta actctttata tgacagttct ttccttcatt
     5701 atcggaggct tcttggggct agtggcaggt ctctttctcg tcttgacagc gccaggtggt
     5761 gtcttggaga ataaagtcgt attctggatt ttagacaaaa ttacctcaat ttttcgtgcg
     5821 gttcccttta tcatcctctt ggcaatcttg tcaccacttt ctcacttgat tgttaaaaca
     5881 agtatcgggc caaatgcagc ccttgtccca ctttcttttg cagtttttgc cttctttgcc
     5941 cgtcaggtgc aggttgtctt ggctgaattg gatggcggtg tcattgaggc ggctcaagcg
     6001 agcggagcga ctttctggga catcgtgggt gtttacctat cagaaggtct tccagatttg
     6061 atccgtgtga cgactgtgac cttgatttcc cttgttgggg aaacagctat ggccggtgcg
     6121 gttggagctg gtggtatcgg taacgtagcc atcgcttatg gatttaaccg ctacaatcac
     6181 gatgtgacca tcttggcaac catcgttatc attttgatta tctttgcaat ccaattctta
     6241 ggagatttct tgactaagaa attgagccat aaataaaaaa gagccgtgtg gctcttttta
     6301 actgatcaga ttttctgggc aaatttttta ctcaaggctt gtccaatcaa ggcacccact
     6361 agggctccga tgacaatact tgcgataaat agaaggacag ttccaggggt tggagtgacc
     6421 atgatacggt cgatatattc ttgggatttt cctcttgcca gaagagtagc catataggct
     6481 ttgggcgcaa tccacataag caagattggt cctgttgtac taaaggcgaa aataatgaaa
     6541 gaaaggaagt tctttgtttt gtccttgtat tttcctaaat gagctactcc atctgctagg
     6601 aggccacaga taattccagg aaggaaggaa ccagcaccgt gtttagttcc caagaaaaag
     6661 agggcaatga caaggccgat agtggtaatg gctccaaagc gcggaacttt tgcgactagg
     6721 atcatataga cgctaccgcc gacaagggca gtaaaggcag gcgcataaaa catgtttcca
     6781 gtttggtcaa agagattgcc caaaaggaca ccaatcccca tgcagaggaa gtaaagaact
     6841 gcaaaaagca gtgtagttaa gatagatttc ttcatgaatt gtctcctgat aattttttca
     6901 caattctcat tttatcatgg tttggtggga ttgtaaatgg atactagaag tttttgaaaa
     6961 cgcttgaaat atgatataat ggtttcatag ttatttttag gggaatatca tgggtagatt
     7021 tttagacttt gtctttaatc gtttcttttt agggatgatt gcgacagcct tattttggct
     7081 attaacttta gcaggaggga ttatccttgg tctagcgccg gctagtgcca ccttgatgag
     7141 cttatatgca gaacatggtt atagctttcg ggaatacagt ttgaaggagg cttggtctct
     7201 ttacaagcaa aattttgtct caagcaacct gattttctat agctttttag gtgtgggtct
     7261 agttttgacc tatggtttgt atctcttggt gcaattgcct catcagacca ttgttcattt
     7321 gattgcgacc cttttgaatg tcctagtagt tgccctgatc tttttggctt atacagtatc
     7381 tttaaaatta caagtttatt ttgccttgtc ctatcgaaat agtctcaaat tatccttgat
     7441 tggcatcttt atgagtctag cagctgtggc taaggttctc cttgggactg tgctacttgt
     7501 agcaattggt tattatatgc ctgccctgct attttttgta ggaattggga tgtggcattt
     7561 ctttatcagt gatatgttgg aacctgtcta tgaaatcatc catgaaaaat tggcgacaaa
     7621 atagaatgaa gcagttttgg ctacatacgc ttctaagaac ctatagttca gtgatgatca
     7681 ttatcattgc gagttttgca atcttactct cttacgctga ctgggattca cgtgaaaagg
     7741 aagcccagag agtagcccag cgtgtaactg ctagaacagt gagtgaaatt gaatattacc
     7801 atagagagtc aacccagata gctcaggctt tagttgaaaa tcaagctcgt atcgagggaa
     7861 tctataaata ctttagcctt agcatgccag actattttta ctggcaatta gagcggaaag
     7921 cttcgcctta tatatcagtc tctctgtatg aaaatgttga tgacctctat gttcgaaatg
     7981 attttgtaac tggggtggcc attgcttttc aagattacaa ggaagtctat gtttctacta
     8041 aagacaaacg tagtggagaa aaaatcaggg ctgaggattt caaaccagca ggaaatagtt
     8101 ttgccattcc ggtgtcagat ccagtgtcag atcaagattt aggagtgatt tacatctcct
     8161 tggatcctgc tgttttatac catgccattg ataatactag aggtcatact ccgatggcag
     8221 taacagtgac ctcacctttt gatacggaga tttttcatat tggtgagaca gttgataagg
     8281 agagtgaaaa ttggctagtt ggcttaactt ctcatggata tcaggttcag gtggcagttc
     8341 ctaaaaactt tgttttacaa ggaacagtga ctagctctgc tttgattgtg ggtttgagcc
     8401 ttctctttat tgtcattctt tatctgactt tgaggcagac ttttgctaat taccaaaagc
     8461 aggtagtgga tttagtagaa tccattcaag tcattgctca aggcgaagag gggcgtcgga
     8521 ttgacatttc cgagaaagat caggaattgc tcctaatcgc ggagacgacc aatgatatgt
     8581 tggatcgatt ggaaaagaat atccatgata tttaccagtt agaactcagt caaaaagatg
     8641 ccaatatgcg ggccttgcag gcgcaaatca accctcactt catgtataat acgctggagt
     8701 tcttgcgcat gtacgcagtc atgcagagtc aagatgagtt ggcagatatc atttatgaat
     8761 tcagtagtct cttgcgtaac aatatttccg acgaaagaga gaccctcctc aaacaggaat
     8821 tagaattttg ccgtaaatac agctatctct gcatggttcg ctatcccaag tccattgcct
     8881 atggtttcaa gatagatcca gagttagaga atatgaagat tcccaagttt accttgcaac
     8941 cgctggtaga aaattatttc gcgcatggtg ttgaccacag gcggacagat aatgtgatta
     9001 gcatcaaggc tcttaaacag gatggttttg tggaaatttt ggtggtcgat aatggtagag
     9061 gaatgtcggc tgaaaagttg gcaaatatcc gagaaaaatt aagtcagaga tattttgaac
     9121 accaagccag ctacagtgat caaaggcagt ctatcgggat tgtcaatgta cacgagcgtt
     9181 ttgtgctcta ttttggagac cgctatgcca ttacgataga gtctgcagag caagccggtg
     9241 ttcagtatcg tattacaatt caagatgagt agaaagggag aaaatgtata aagtattatt
     9301 agtagatgat gagtacatgg tgacagaagg tctgaagcgt ttgattccct ttgataagtg
     9361 ggatatggag gtcgtcgcaa cagccagtca tgccgatgaa gctctagaat atgttcagga
     9421 aaatcctgtc gatgtcatca tttccgatgt caatatgcca gacaaaacag ggcttgatat
     9481 gattcgggag atgaaagaga tcttaccaga tgctgcttat atcctgctct caggttacca
     9541 ggagtttgat tatgtaaaaa gagcaatgaa ccttagtgtg gtggactatt tggtcaagcc
     9601 tgttgataag gtagagctgg gaaatctgct ggagaagatt gcaggtcagc tcggcgagag
     9661 agggaagaaa agtcagactc ttagtcaaga attagacgag gctggatttg ttagttattt
     9721 aggggataag gagaattggt ggataggtct atccaaggaa aaacaaggtt ccttcaccat
     9781 tccctactat gtcttgggtc aagactggca gattttcatt tctgaccaac ccctagatgg
     9841 tttagtcgtt acaccttttg aagctcctta tcaagaacac tttgaacgct ggaagctgaa
     9901 tgctgagaaa accctctttt acggctctgt aaatctgcag cagtctgaga gtctctttgc
     9961 ctattacgaa ccgatttata gggttatcat tcagggaaat ctcaatcaaa tcgtagaaga
    10021 gttaaatctc ttggagaagg tagttcttga aaatacgccg cgtgttccga ttactaaaca
    10081 gctttttatt cagtttgtca tggatgtttt ccatttattt gaacatctca aagctgatga
    10141 cctgacagac atcgtcaaaa ccattcatgc tattcaatcc ttcgatgaat tggttcctta
    10201 tatcaaggaa actctgagca gctttttcgg tcaataccgt atgaatgaaa atgtggtcag
    10261 tgtgctggaa gtcattggtc gtgattacca aaaagagctt tccctcaagg atatcagtaa
    10321 ggctctcttt atcaatcctg tctatctagg gcagttgatt aagcgtgaaa ccgattcgac
    10381 ttttgcagag ttactaaaca aacaacgtat taaggctgcc caacaacttt tgctttcaac
    10441 tagtgacagc atcgaagata tttgttatgc tgttggttac agtaaccttg gatatttcta
    10501 taaagttttc cgaaaattgt gcggaaaatc gccaaaagcc taccgaaaac aggtagaaac
    10561 tatactataa aatttgtatt cctttacaaa aggtgctata atattatcag gaggttctat
    10621 catgaaaaag aaaccaattt atctatgggt cttgctaatc ttgtctgccc ttatttcagt
    10681 tccgtctctg tttggaattg tgagtccctt gcctagtaaa gaagcccttc gtgctgctca
    10741 gaaacaagtt gcaggggtca atgctcagca attagaagac cagcttaatt atacctatag
    10801 agtagcagaa gcatctcatt ctatttttaa tgttgctttg attgtgctat ctactatttt
    10861 agtggtcgta gcgattgtct tccttgttcg taaaaatttg caatatgcaa actatactta
    10921 cgttggctat gttttgttag ctattattgg ttcgatttat ggctatgttg gtttacaaga
    10981 cgctgtgcag ttggttcaag atgagagcat gcgtttgaca gtgagtattg gttcaaaagc
    11041 tgttagcatt ttctatatcg tcatcaatgt tctcttccta gcccttgtct tctataagat
    11101 gtggcgacaa cagaaagcct tggcagagga agaggaaaca gaagagcttg cctaagtatt
    11161 gacaaaaaag aactatcaag atacaatctt ggtagttgtt ttttgattat agataaaatc
    11221 atggaggtac atatgaagac aatttcttta gtttatatta gtttgagtgg caacactgaa
    11281 agttttgtga cgcgcttgaa agactatctc ttgtcccagt acaaaaggat tgaggttcaa
    11341 aagattcata tcaaggattt ggtcaaggaa ggcaaaaatt tctatgaaat ggaccatccc
    11401 tatgtcgctt ttttgccgac ctatctcgaa ggtgggaatg gcgtggataa cggagatgtt
    11461 gagattttga cgacaccggt gggagatttt attgcctatg gtaacaatgc tagtaagtgt
    11521 tttggtgtgg ttgggtcagg aaatcgtaac tttaataacc aatactgcct aacagccaag
    11581 caatacagtc aacgctttgg cttccctgta ttggctgact ttgaaatgcg aggcatgctg
    11641 gaagatatca aacatgtcgc agctattatc gcagatttgt atgagttgga aaaggagaat
    11701 taatactcaa tgaaaatcaa agagcaaact aggaagctag tcgcaggttg ctcaaagcac
    11761 agctttgagg ttgcagatag agctgacgtg gtttgaagag attctcgaat agtataaagt
    11821 tcttataaga ggtggttgaa gttgttcaac tgttttttga gtataaacag tctttaagaa
    11881 cgtaaaaaag cataagttca ggtcttcaaa accttgttct tatgcttttt atcatagaaa
    11941 tatttgctga attttctctt gaaatgaaac cttatcttca tctcgcgctt gtcccttacc
    12001 ctgctttttc gattgcgagt gcgtagataa agaagatggc gaagccaaag aggaaaatca
    12061 atcccgcaat ggcaaggtgt ttgagccaag aaggaagatt tttgttttca cgcgttacca
    12121 aggcgtaatt caaaagagca aagaaaggtg ttgtcaggaa agatccaatc atggcaaagc
    12181 ggagcatggt tgaaacctga ccagcgaaga acttgataat gacgataccg atgatagcag
    12241 tgatggtcat ccagatgttc aaagatttac gattgtcctc tttttgactg attagcagtc
    12301 ggagagattc ctgattaacg cgagaatagc catcgataac agttataact gttccaaaga
    12361 tacagaggaa ggcaataaag gtaatcaagt aacgggacca ttcgccaaga acagaggcat
    12421 acatgcccac gaattgagag atgtatttgg ctgaagcagc ttcaaccgcc tgccctgtag
    12481 gatactgaat cagtgctccc agtgccacaa agaagacggc taggatagct gttccaatat
    12541 aaccagtgtt aaagtcaaac agagcgtctt ctgtgttaaa gttgacggtc tttctctttt
    12601 cagctgacca aagtgaattg atggctgaaa tttcaatagg agccggcatc catcctagga
    12661 gggagacgat gaagggcaga gctgccattt gccaaggtgt cttctcgaca aaatcagaac
    12721 tgtattctgg atgcttgacc gctgctatga taactgccag aacagtcgca atggttaagg
    12781 cagacataat ccatttgacc atgccgtcta aaagtttgta gcctccaaag agtagcatag
    12841 cccaaatgat tgcaacgaga atgagggacc actgagtaat gctaagtcca atcattggga
    12901 aggcactggc gatgatagct gagcacagaa tggcaacacc agccgtgttg accatagccg
    12961 aaaagacatt gaggataaag aaaatccaga gatagagttt tcctttttcg gcataacctt
    13021 caaccaaagt ctttccagta tcagctgtgt attcagcacc aaaacggaaa aatggatatt
    13081 taaagacatt ggctaagatg accaagagaa gtagagacca accgtaagaa ccgccagctt
    13141 gagttgagga tacaatgtgg gaacctccaa cagcggcagt tgccattagg attccaggtc
    13201 ccattgcttt tagcttgctt gcccaggttg attgatttaa ggaaatagct tgcgacatga
    13261 taaatactcc tttttgaatt ttcagaataa tctgtatatg taatctatat tctacaaaaa
    13321 attttggaaa aatgcaagaa tattttgaaa aaagatagaa aatttacaaa gaaaatctga
    13381 aataactgtt atgatatagc atattgaaac tagaatagta cacctttgct tctaaaacat
    13441 tgttagaaat cgatttgact gtcctgatcg atttatcctg ttcttatttc atttcactat
    13501 agtaaggtgc agcaggataa agaaaaaccg agaagtttct ttctcggatt tgcttattat
    13561 gaggtttcta ttttctatgc tccaagagtt gattgatgtg atctactttt ttagcctctc
    13621 ttttatagag aatagcccag atgatgagat agacaatcgc aaactcgata atgagctgga
    13681 ggtagaaaat ccagtggaaa gggaaccaac cagcaagagt tgctagtggg acaaagccag
    13741 ccagcataag gaagaaatga gtcagagtgg cacgaagcat gctccagtca cggctgaata
    13801 agcggttgcc aaagttgaag agcataccga tggctgccca gataagtgtg cagtagagca
    13861 agaccagggc accgtgaacc tgatgctgat ccatcacttg gccgatgaga gagtagggat
    13921 ttagtggtgc gtaggtattt ggtgcataaa tgagtgaaaa gaggatggag aggatgaggc
    13981 cgataagaac accggcagct gcatcgtgaa atacttgttt tttcatagtt ctaatttctc
    14041 cttgatggtt tttagataac ggcgtgaaga gtaggtgaag ctttcgtttt ttaagaaaat
    14101 ttctaccaga ccgtttggcg tgagcttgag gtgagagatg gaatcgatat tgatgatttc
    14161 tgattgggaa atttggataa aattgcttgg caagagttta agaacctgat agagtcgcaa
    14221 atcaatgctg taggtctgac tcgcggtttc tgctagaacc ttccgattct ctatatagaa
    14281 gcgctgaatc ttgccaatct caactagata gacctgatca tcgattttcc ctttgatttt
    14341 ttctctttgg tccagatttt ctgcgaactc gatgactttc tggactttat ctgtcggctg
    14401 aggtgcttgg acaatcagct tttcctcctc gtaagtctca ctaatctgta gttctacttt
    14461 cataaatttc tctccttgtt tttcatacaa aattaatctc acttcttgta cacctttatt
    14521 aatactcttc aaaaatctct tcaaaccacg tcagcgtcgt cttgccatag gatagttgtt
    14581 gactttgtca gttttatcta caacctcaaa acagtgtttt gaactgtctg cgcctagctt
    14641 tctagtttgc tctttgattt ttattgagta taccactatt ttactccctc tggcaaggga
    14701 ctttgtctat gtggagggat tgggctccta tgtggtggag cttttctgtt ctttctgaaa
    14761 tatggtataa tagcactaat taatttctag gaaaatagat acagaaaggg gctgaaagat
    14821 gtctcatatt attgaattgc cagagatgct ggcaaaccaa atcgcggctg gagaggtcat
    14881 tgaacgtcct gccagtgtgg tcaaagagtt ggtagaaaat gccattgacg cgggctctag
    14941 tcagattatc attgagattg aggaagctgg tctcaagaag gttcaaatca cggataacgg
    15001 tcatggaatt gcccacgatg aggtggagtt ggccctgcgt cgccatgcga ccagtaagat
    15061 aaaaaatcaa gcagatctct ttcggattcg gacgcttggt tttcgtggtg aagccttgcc
    15121 ttctattgcg tctgttagtg tcttgactct gttaacggcg gtggatggtg ctagtcatgg
    15181 aaccaagtta gtcgcgcgcg ggggtgaagt tgaggaagtc atcccagcga ctagtcctgt
    15241 gggaaccaag gtttgtgtgg aggatctctt tttcaacacg cctgcccgtc tcaagtatat
    15301 gaagagccag caagcggagt tgtctcatat cattgatatt gtcaaccgtc tgggcttggc
    15361 ccatcctgag atttctttta gcttgattag tgatggcaag gaaatgacgc ggacagcagg
    15421 gactggtcaa ttgcgccaag caatcgcagg gatttacggt ttggtcagtg ccaagaagat
    15481 gattgaaatt gagaactctg acctagattt cgaaatttca ggttttgtgt ccttgcctga
    15541 gttgactcgg gctaaccgca attatatcag cctcttcatc aatggtcgtt atatcaagaa
    15601 cttcctgctc aatcgtgcta ttttggatgg tttcggaagc aagcttatgg ttggacgttt
    15661 tccactggct gtcattcaca tccatatcga cccttatcta gcggatgtca atgtgcatcc
    15721 aactaagcaa gaggtgcgga tttccaagga aaaagaactg atgaccctgg tttcagaagc
    15781 tattgcaaat agtctcaagg aacaaacctt gattccagat gccttggaaa atcttgccaa
    15841 atcgaccgtg cgcaatcgtg agaaggtgga tcaaactatt ctcccactca aagaaaatac
    15901 gctctactat gagaaaactg agccgtcaag acctagtcaa actgaagtag ctgattatca
    15961 ggtagaattg actgatgaag ggcaggattt gaccctgttt gccaaggaaa ccttggaccg
    16021 attgaccaag ccagcaaaac tgcattttgc agagagaaag cctgctaact acgaccagct
    16081 agaccatcca gagttagatc ttgctagcat cgataaggct tatgacaaac tggagcgaga
    16141 agaagcatcc agcttcccag agttggagtt tttcggacaa atgcacggga cttatctctt
    16201 tgcccaaggg cgagatggac tttacatcat agatcagcac gctgctcagg aacgggtcaa
    16261 gtacgaggag taccgtgaaa gcattggcaa tgttgaccag agccagcagc aactcctagt
    16321 gccctatatc tttgaatttc ctgcggatga tgccctgcgt ctcaaggaaa gaatgcctct
    16381 cttagaggaa gtgggcgtct ttctagcaga gtacggagaa aatcaattta ttctacgtga
    16441 acatcctatt tggatggcag aagaagagat tgaatcaggc atctatgaga tgtgcgacat
    16501 gctccttttg accaaggaag tttctatcaa gaaataccga gcagagctgg ctatcatgat
    16561 gtcttgcaag cgatctatca aggccaatca tcgtattgat gatcattcag ctagacaact
    16621 cctctatcag ctttctcaat gtgacaatcc ctataactgt cctcacggac gtcctgtttt
    16681 ggtgcatttt accaagtcgg atatggaaaa gatgttccga cgtattcagg aaaatcacac
    16741 cagtctccgt gagttgggga aatattaaaa gtataaaaaa gtctgggaaa aattttcaaa
    16801 atcagaaaaa cgcataaaat caggtgttca aaaaccttga ttttatgcgt tttatcatag
    16861 aaatatttac ttcatttttt cctaattctt ttcgaaactc tttttaaacg acgtcagttt
    16921 tatcagtaat ctcaaaacag tgttttgagc taattttgcc agttttgtct gtaacatcga
    16981 agttgtgttt taccactctg cgactggttt cctagtttgc tctatgattt tcacagagta
    17041 ttaaattgcg attttgccaa gtttctttat tcgtctaaaa gtagagtctg ttctatgcgt
    17101 ctaatgtacg aattaggttg accatttcaa tagctccttg tgcacactca gaacccttat
    17161 ttcctgcttt agtaccagct cgttctatgg cttgttcaat tgtatctgtc gttagcacac
    17221 caaacataac aggaatttcg ctatttaaac tgatttgggc gattccctta gatacctcgc
    17281 tacatacata atcataatga cttgtattcc ctctaatgac agctcccaag cagataattg
    17341 catcatattt tttacttttt gccatttttg atgcaatcag tggtatttca aaagctcctg
    17401 gaacccaggc tacctctata tctttctcgt ttacattctc tcttttgaga ttatctagtg
    17461 ctccagataa taattttgaa gttataaatt cattaaatct cgctacaaca atacctattt
    17521 taatattgtt tgctactaaa ttaccttcat aagtgttcat ttatttttcc tccatattta
    17581 aaatgtgacc cattcgattt ttctttgttt ctaaataaaa actatcgtaa ggattggctt
    17641 ctatttcgat tgatattcta ctggaaatgg taattccata tttttctaac tgttcaacct
    17701 tgtcaggatt atttgtcagt aaatgaagtg actgaagtcc cagatcttta agcatttgtg
    17761 ctccaatatg atattctctt aaatcacctt caaagcctaa tgcaagattg gcatcaagcg
    17821 tatccatgcc ttgatcttgt aaatgatagg cttttaattt attgataagt ccaattcctc
    17881 gtccctcctg tcgcaagtaa agtaagacac ccgaaccatt ctcaacaatt attttcatag
    17941 ctttatcgaa ttgctgtcca caatcgcaac gtaaagagcc taaaacatct cctgttaaac
    18001 attcggagtg gacccgacat aatacattgg cttcatcctc tatgtttccc ataataagag
    18061 caagatgatg ttccccattt agtttatcta tatagctaat tgctttgaaa ttaccgtatc
    18121 tagtaggcat attgacagtt gaaactcgtt ctaccagctg atcatatgct tttctatatt
    18181 cttgtaattc tttgatggta attagtggaa tgttgtgttt cttcgagaac tgaattaaat
    18241 catctattct catcattttg ccatcatgat tcattatttc acaacatagg ccacactctt
    18301 ttagtccagc taattttaat aaatcaacag ttgcttctgt gtgtccattt ctttctagaa
    18361 caccaccttt ttttgcaatt aaaggaaaca tgtgtcctgg cctgcgaaaa tcagagggtg
    18421 ttatatcttc agctacacac atacgtgcgg tcagtcctct ctcctcggca gaaatacctg
    18481 tggtcgtttc tttataatca attgaaactg taaaagcagt cttatgatta tctgtattgt
    18541 tttcaaccat aggtgaaagc attaattgat tagctaaact ttcgctcata ggcatacaaa
    18601 ttaatccttt ggcataagta gccataaaat taacattttc tgttgtagct gcttgtgcag
    18661 aacaaattaa gtctccttca ttttctctat ccttgtcgtc tataacaaga acaagtcgtc
    18721 ccttctgcaa tgcttctaat gcttcttgta tttttcgata ttccattgac tgattatcct
    18781 ttctgctaaa atccattttg atataatagt tccttcgata tttctgattt tggagagtta
    18841 tccatcagtt tttgcacata tttacctaag atatcatttt caagatttac tgtactcccg
    18901 acttgtttac tcttaagaat ggtttgtttc aaggtatgag ggataacaga tactgaaaag
    18961 tttactttgg agactttagc gacagtcaga ctaatgccgt caattgtaat agatcctttt
    19021 tcaactatta aatctaaaat ttctttttgt gtgttgattt gataccatac agcattatca
    19081 tcttttttta ttgacgagat ttttcctgta ccatcaatgt gtcctgtaac gacgtgaccc
    19141 ccaagtcgac cgttgacaga taaggctctt tctagattca cctcacttcc atgttttaat
    19201 agagtaagag ctgttcgact ccatgtttca ttcattacat caactgtaaa ggattgatga
    19261 ttgaaatgag taactgtaag acagatacca tttactgcta tactatcgcc taaatggata
    19321 tccgttaata tttttgaggc tttaattgat agtttacaat tacgagagtc tttctgtatt
    19381 ctttcaactt ttccgatttc ttcaattatt cctgtgaaca tggataaatc acttcacttt
    19441 ctatgagata gtcatttcct atttgagaaa aagcataagg tttcaatcta atagcgtcat
    19501 ttggcaaaga aatgccttca cctccgacag gaaacttggc actgcctcca aaaatttttg
    19561 gtgcaatata tattttcagc tcatcaacaa tttgttgttc caaagcactc caattcatta
    19621 gactgccccc ttctagaact aggctatcaa tctgcatgtt tcctagatgt tgcattaaac
    19681 tcgataagtc tatatgattg ccttttttct ttatggaaag tatttcacag ccatgatttt
    19741 gatatagctt cattttattt ttgtcttcag aggaagtggc aatgtaagtt ttaatatcat
    19801 ttgctgtttt tacgatttta gaggtaagag gagttcgtaa atgtgtatcg catatgatac
    19861 ggataggatt tttcccttcc tccaatctac atgtcagcaa aggatcgtct tgaataacag
    19921 tattgactcc caccataatt gcactaacat ggtgtcgtaa ctgatgcaca tgctttcttg
    19981 cctcttcttc agtaatccat ttggattgat ttgttttagt ggctattttt ccatccattg
    20041 tcattgcata tttcataaaa acatagggta catgctgggt aatatacttt ctaaaacttt
    20101 ttattaagtt aagacactca ttttctaaaa ttccaacagt aacttgaaga ttattttcct
    20161 caagtatctt tactcctttt ccagatacaa taggattaca gtctaggctt ccaatgacta
    20221 ctcttgtaat accactatcg attatagcat ctatacaagg aggtgttttc ccgaagtgac
    20281 aacagggttc aagtgttaca taaagcgtcg ctccgacagg ggattctcta cagtttttaa
    20341 gagcatttct ctcagcatgt gagccaccaa aaaactcatg ataaccttgt ccgatgatgt
    20401 gattatcttt tacaataact gcgccgacca taggattggg attgacgtaa ccagcccctt
    20461 tttgtgccag ttttattgct aatttcatat attttgaatc gctcatctca ctacctccaa
    20521 aaaaatatac cttgaatagg agactactca aggcatacaa aagaaaactt atgcgattaa
    20581 caaaaatgct ctgaaatgac aagtaatcat ttcagagcac gcaaaaagca caaatatact
    20641 tttatcttct ttcatccaga ctatactgtc ggctttggaa tttcaccaaa tcatgccttt
    20701 cggctcgtgg gctataccac cggtagggaa ttgcaccctg ccctgaagat agttattcaa
    20761 ttacagatga ttatagtact taattttgaa tatgtcaaca gataaatacc gattgttttt
    20821 gatatactgt atttgtgata atcgattctc gctcctcgga taaagaaaat atgatatact
    20881 agataaacga aataagagag aaggaacact atgtacgcat atttaaaagg aatcattacc
    20941 aaaattactg ccaaatacat tgttcttgaa accaatggta ttggttatat cctgcatgtg
    21001 gccaatcctt atgcctattc aggtcaggtt aatcaggagg ctcagattta tgtgcatcag
    21061 gttgtgcgtg aggacgccca tttgctttat ggatttcgct cagaggatga gaaaaagctc
    21121 tttcttagtc tgatttcggt ctctgggatt ggtcctgtat cagctcttgc tattatcgct
    21181 gctgatgaca atgctggctt ggttcaagcc attgaaacca agaacatcac ctacttgacc
    21241 aagttcccta aaattggcaa gaaaacagcc cagcagatgg tgctggactt ggaaggcaag
    21301 gtagtagttg caggagatga ccttcctgcc aagatcgcag tgcaagcaag tgctgaaaac
    21361 caagaattgg aagaagctat ggaagccatg ttggctctgg gctacaaggc aacagagctc
    21421 aagaaaatca agaaattctt tgaaggaacg acagatacag ctgagaacta tatcaagtcg
    21481 gcccttaaaa tgttggtcaa ataggagcag agaatgacaa aacgttgttc gtgggtcaag
    21541 atgaccaacc cactctacat cgcctatcat gatgaggagt ggggccagcc cctccatgat
    21601 gaccaagcgt tgtttgagtt gttgtgtatg gaaacctatc aggcaggcct gtcttgggaa
    21661 acggtactca acaaacgcca agctttccga gaagcctttc atagctatca aattcactca
    21721 gtcgcagaga tgactgacac tgaattggaa gccatgctgg agaatccagc tatcattcga
    21781 aatagagcca agatttttgc tacacgcgct aacgcccaag cctttctaca gttacaggca
    21841 gagtacggct cttttgatgc ctatctttgg tcttttgttg aggggaaaac tgtcgttaac
    21901 gatgttcctg attatcgcca agccccagct aaaacaccct tatctgagaa attagccaaa
    21961 gatctcaaaa aacgagactt caagttcaca ggcccagtcg ccgtattgtc ttttctacag
    22021 gctgcagggc tagttgatga ccacgagaat gattgtgagt ggaaaggtct taaatgatgt
    22081 ctaacaaaaa taagggaatt ctgatttttg cgattctcta tacagtcctc tttgtgtttg
    22141 atggcgttaa attgctggct tctttaatgc catctgccat tgcaaattat cttgtttatg
    22201 tagttttagc tttatatggc tccttcttgt tcaaggatag attgatccaa caatggaagg
    22261 agattagaaa gactaaaaga aaattcttct ttggagtctt aacaggatgg ctctttctca
    22321 ttctgatgac tgttgtcttt gaatttgtat cagagatgtt gaagcagttt gtgggactag
    22381 atggacaagg tctaaatcag tctaatattc aaagtacctt tcaagaacaa ccactactga
    22441 tagctgtttt tgcttgtgtc attggacctc tggtagaaga attatttttc cgtcaggtct
    22501 tattgcatta cttgcaggaa cggttgtcag gtttactaag cattattctg gtaggacttg
    22561 tttttgctct gactcatatg cacagtttgg ctctatcaga gtggattggt gcagttggtt
    22621 acttaggtgg aggccttgcc ttttctatta tttatgtgaa agaaaaagag aatatctact
    22681 atcccctact tgttcacatg ttaagcaaca gcctctcctt aatcatttta gctatcagta
    22741 tagtaaaatg aaatgagaac aggacaaatc gatttctaac aatgttttag aagtagaggt
    22801 gtactattct agtttcaata tactgtaata tgtgatgaaa atgccagtaa tgataccgag
    22861 aaaaaagctg agaaactttt cccagcttta tttgttatag tcaaagagaa tgacttgttc
    22921 ctgtgcatct acatgagcat ggaccccaaa gggtacaatt gctcttggag ttgcgtggcc
    22981 gacattcaga ttatagacaa tcgggatatt gctgtcaatg atatccaata gtgcctcttt
    23041 atagtcgtca tggaaagttt catccatagg ttttccgacc aagagtccat tgatgaccgc
    23101 gaatatgcca gtgtccttta aagttagcaa catctttttg aagtcttctg gcttaggctt
    23161 ttcttcgctt gtttcgagca agaggatttt cccttcccag tctgacaagt cagggaaaag
    23221 tttgtatttt tggcagagtt ccgtgctatc tgcgtatcga gagttgtcaa agatatcgta
    23281 gagggattcg aggcaaccac cgaggatttt cccctcgaac tgagcacttc cttgcaacaa
    23341 gtcaaaacct gtatttgtat gactgacacg aggtgttccc agggccgtgg gactaaaatc
    23401 agttcgttcc tcataccaaa cgtcactagg gcggatttct gaaattcttc ccgtctcaat
    23461 caattcttta aagtagtgaa ggctataggc tagcatttct ttgtctaatt cacaaatgtc
    23521 tgctaaaaag gattgaccat aaaaagtctt gattcctaat ttatgcaaca tgaggtggtt
    23581 catggttgta tccgagaagc caagaaaaat tttttgtttg ataacctttt ggagttggtc
    23641 attttcaaaa agataaggta gcaagcgata ggtatcgtct ccaccgatgg cacataggat
    23701 catgtcgatg ctatcatcag aaaaggcatg aatcaaatcc tctgcacgag cttcaggatg
    23761 gtccttgata aagtctaatc cttttaacga atggggcaaa aagatgggat tgagtcccag
    23821 atccttgaga cgttggatac ccaagtccac ttcgtgtttg acaaaatcct ctccgataat
    23881 gccactagat aaactaacaa taccaatagt agaaaccata tctcatcctc ctagaaatag
    23941 attgagccta ttttatcaca aaatataaga gaaagctatg tgggatttca gaagaatact
    24001 tttaatactc ttcgaaaatc tcttcaaacc acgtcagttt tatctgcaac ttcaaagctg
    24061 tgctttgagc aacctgcagc tagcttccta gtttgctctt tgattttcat tgagtacaac
    24121 tcaaaaaagt aagtgaaaaa gcaaccgcac ctgcagttgc ttttatcgtt ttcttattct
    24181 tgatagcgtg ttggtcctgc acttgcacta cggatattca agcgtttctt gagatagaag
    24241 cgaagggcta ggagggctgc tccaataata gctagtggca atggatccag tactgggtta
    24301 aggctagctg gtaggaagct tgttgcaaag aagacaagca accaaaggaa catagaagct
    24361 aggataacta gtacagattt ccagaaaggt ggacgttgac tgcgatccat atctggtcca
    24421 tagtattggt aaacaaagta gtacatcaag tagaaggcaa atccaccaac cagtccaact
    24481 aatagaagag taatcaatcc atagccgaaa gcttgatctg ccgcaaagaa ggttgtgagg
    24541 gcgctgacaa gggcaaagag gctagtgatg aaaagagctg agtccataat catcagtttt
    24601 ggatcatcat tttcttttgg atgctctttt tcgtactgct ctttgacagt gaagctatga
    24661 gcccaatgag ttggtgcgcc gtatagggaa cgggcagttg tacctttaga ttgctcctca
    24721 aggatttggg gaatgacttc ctcaaaaata gtctggattt cagcgtctgt tttcccatct
    24781 ttgatgaatt gttgggtagc aatgtggaca aactcttggt ttttcttagt taatttttgt
    24841 agatcaattt gagacatagg aactcctctt agaaccattt tttatggatg agatagagag
    24901 tgagcgagac actcatagca aaggcgataa agacgattaa ccagaaggca tttggctctc
    24961 cgtttagggg aatttcatta tccttaaagt tcatcccgta ggcagaaaag accatggttg
    25021 ggatggacat gacgatggtc acaagggcca aggttttcat gatgttgttc tggttgttag
    25081 aaatgataga ggcaaaggtc tctgtcatag aatgcaagac gtttccataa atatctgcca
    25141 tctcgatggc ctgttgggtt tcaatcaggg tgtcttcaag caggtcttcg tcctcaaggt
    25201 atttcttgat attgctggtt gaactggtca atttcttaat cacgcgctca tttgttttga
    25261 gggaggcctt gaaatagacg atagtttttt ccaattccat gagctcaatc aattcttcat
    25321 tacgagttga ttgatgcagt tgactttcga tttgttcact cttgcggtcg attgaacgaa
    25381 gggctgttag gtaaagctct gcattgcgat aaagaatttg aaagataaaa cgtgaacgca
    25441 tgaaggtata gaaattacgc aatcgacggt tgataaagac atcaaggaca ggtagtggtt
    25501 ccaaacacgt agtgataatg gtttcctcag tgatgataat accaagcggg atggttacgt
    25561 agtaggtgcg gttatttctt tcctccgtga ccggcacgtc tacgataatc agggtatact
    25621 cgtcttcaat ggtaatacga gacatttctt ccgcatcgag cggtgctcga aggtcggcaa
    25681 tatcaatatc gaaggtgttg gcgatttcga gtgattcatt ttgagtcgga ttgacgagat
    25741 tgatccaagt acccggttca agcgtatcga tctctttaaa ttcagttgtt gtagagagaa
    25801 aaacttgttt catatccctt atcctttctc atttttcaga ttttttcaca ctgtactatt
    25861 atactacaaa atcggccttt tgggtaatag aatctcactt tttttggtat aatggtaagc
    25921 aataatggac taggaagaac aaagatgcaa gataaaattg tcattcatgg ggcgcgtgcc
    25981 cataatttaa aaaatattga tgtggagatt ccgcgagaca agttggttgt cgtgactggc
    26041 ttgtcaggtt cagggaagtc cagtctggct tttgatactc tctatgcgga gggacaacgt
    26101 cgctatgtag agagtttgtc cgcctacgct cgtcagttct tgggaaatat ggaaaaacca
    26161 gatgtagatg ccattgatgg tctcagccca gctatttcca tcgaccagaa aacgactagt
    26221 aaaaatcctc gctcgacggt gggaacgacg actgaaatca atgactatct gcgtctcctc
    26281 tacgcacgtg tggggacgcc ttactgtatc aacggacatg gagctatcaa tgcttcttct
    26341 gtggagcaaa tcgttgataa ggttttggag ttacctgaac gccagcgctt gcagatcttg
    26401 gctcctgtca tccgcaagaa aaaaggccaa cataagagtg ttatcgagaa ggttcagaaa
    26461 gacgggtatg ttcgtgttcg tgtggatggg gaagtctatg atgtgaccga agtgccagag
    26521 ttgtctaaga gcaagcaaca caatatcgat gtcgtggttg accgtattgt tatcaaggag
    26581 ggcattcgta gtcgtctctt tgattccatt gaggctgccc ttcgtattgc agaaggttat
    26641 gtcattatcg acaccatgga cgattcggag ttgctcttct ctgagcatta tgcctgtcca
    26701 gtttgtggtt ttactgtccc agagttagag cctcgtctct tctctttcaa tgctcctttt
    26761 ggctcttgta gtgagtgtga cggcttgggc atcaagctgg aggtggatac tgatttggta
    26821 gtgccagatg ccagcaaaac cttacgtgag ggagcgctag caccttggaa tcctatctca
    26881 tccaactact atccaaacat gttagagcag gccatgaaag tctttggagt ggctatggat
    26941 aagccttttg aggacctgtc agaagaagat aagaacttga ttctctatgg gtcagatggt
    27001 aaggaattcc atttccacta tgagaatgaa tttggtggcg tgcgcgatat cgacattccg
    27061 tttgagggag ttatcaataa tatcaaacgt cgttaccatg aaaccaatag cgattacact
    27121 cgcactcaga tgcgtctcta catgaatgag ctgacctgcg gaacctgtca aggctatcgt
    27181 ctcaatgacc aggccttgtc tgtccgtgtg ggcggccagc aagggccaca tattggagaa
    27241 atctcagacc tgtctatcgc tgaccacttg gacttggtga gccagttaac tttgtctgaa
    27301 aatgaagcca tcattgctcg tcccattctc aaggaaatca aggatcgttt gaccttcctt
    27361 aataatgtgg gtcttaacta tctaaccctg tcacgttcag caggaaccct ttcaggtggg
    27421 gaaagtcagc gcattcgttt ggcaacccag attggttcca acctatcagg cgtcctctat
    27481 atcctagacg agccgtcaat cggtcttcac cagagggaca atgaccgcct gattgccagt
    27541 ctgaaaaaga tgcgtgactt gggcaatact cttatcgtgg tggaacacga cgaagatacc
    27601 atgcgtgaag ctgattatct gattgacgtt ggtcctggtg ccggtgtttt tggtggtgag
    27661 attgttgcag caggtacacc taagcaagtg gctcgcaaca gcaagtctat cacaggtcag
    27721 tacttgtcag gcaaacgtgt catcccagta ccagaagagc gccgtgtcgg aaatggtcgt
    27781 tttattgaag tgataggagc gcgtgagaac aacttgcaaa atgtcacggc tcgctttcca
    27841 ctaggaaaat ttatcgcagt gacaggtgtg tcgggttcag ggaaatcgac tctaatcaac
    27901 agcattctca aaaaagccat tgctcagaag ctcaaccgta attcagacaa acctggtaag
    27961 tttaagacta ttacagggat tgagcatgtc gaccgtttga ttgatattga ccagagccct
    28021 atcggacgga cgccgaggtc taacccagct acctatacag gagtttttga cgatatacgt
    28081 gacctttttg ctcagacaaa tgaagccaag attcgaggct acaagaaggg gcgcttcagt
    28141 ttcaacgtca agggaggtcg ctgtgaagct tgctcaggtg acgggattat caagattgag
    28201 atgcacttct tgccagatgt ttatgtggct tgtgaagttt gccacggaac ccgctataac
    28261 agtgaaaccc tagaagttca ctacaaggaa aagaatattt cgcaggtctt ggatatgacg
    28321 gtcaacgatg cggtagaatt tttccaacac attccgaaaa ttcaacgcaa actccagacc
    28381 atcaaggatg tagggctagg ctatgtgacc ttgggacagc cagctaccac cctttctggg
    28441 ggagaagccc aacgtatgaa gttagctagc gaactccaca aacgctcgac aggaaaatct
    28501 ttctacattc tggatgagcc gacgacaggg cttcatacag aggacattgc tcgcctgctc
    28561 aaggttttag ctcgctttgt agacgatggc aatacagtcc tcgtcatcga gcacaatctg
    28621 gatgttatca agacggcaga ccatatcatt gacttgggac ctgagggcgg tgtcggtggt
    28681 ggaaccatca tcgtaacagg aactccagaa gaagtagctg ccaacgaagc cagctataca
    28741 ggacactatt tgaaaggaaa gttacatcat gaataaacgc gtacaagcat ttctagttaa
    28801 aatgcaagaa aaagaactag atggtgtcat catcaacaat cttaaaaacg tctattattt
    28861 gactggtttt tggggctcaa acggaacagt ctttatcagc cgtgaccgtc aggtcttagt
    28921 gacagactct cgctatatca tcgcagctaa gcaagaaacc agtggttttg agattgtggc
    28981 tgatcgtgat gaattggctg tcattgcagg aattgttaag gacatgggct tgactcgtat
    29041 cggttttgaa gatgagattt cagtgtctta ttaccaccgt atgcaggcag cttttgcagg
    29101 tttggacttg tttccgcaaa ctcagtttgt ggaaggtctt cgtatgatta aggatgaggc
    29161 agagattgca gcgattcgca aggcttgttc tatctcagac caagctttcc gcgatgcgct
    29221 tgactttatc aaaccaggaa aaactgaaat tgagattgcc aacttccttg acttccgcat
    29281 gcgtgagttg ggagcatctg gcttatcttt tgatacgatc ctagctagcg gtatcaattc
    29341 ttctaaaccc catgcccatc caatgcacaa accagtggag ttgggagaag ccattaccat
    29401 ggacttcggc tgtctctatg accactatgt cagtgatatg acccggacta tctatctagg
    29461 gcatgttagc gatgagcagg cagagattta caatacggtt ctaaaagcta accaagcctt
    29521 gattgaccaa gctaaggcag gcttaggttt ccgtgacttt gacaaaatcc ctcgtgatat
    29581 tatcattgag gcaggttatg gcgactactt tactcacggc attggccacg gtattggtct
    29641 ggatatccat gaggaaccct actttagcca gacttctaca gaaactatta agacaggtat
    29701 ggccttgacc gatgaaccag gtatctatat cgaaggcaaa tatggcgttc gtatcgagga
    29761 tgatatcctg attacagaga caggttgtga attattgacc ctagctccaa aagagttgat
    29821 agtcatttag ttgtttgtca agaaaaaagt acgaaaatga cgaaaaaagt caaaaaaaat
    29881 taaaaatagg tcgcaagtcg gatgtttttt atggtataat agactaaact gatagtaaca
    29941 tgtagcgaaa ggggtaggta catgattaaa atttatacag tctcaagttg tactagctgt
    30001 aaaaaagcaa aaacctggct caatgcccac cagttaagtt ataaagaaca aaaccttggt
    30061 aaagaaggaa ttacgagaga agaattactg gatattctaa ccaaaacaga taacggaata
    30121 gccagcatcg tttcgtctaa aaatcgctat gccaaagccc ttggagtgga tattgaagat
    30181 ttgagtgtca atgaagttct caatctgatt atggaaacac cgagaatttt aaagagccca
    30241 atccttgtag atgaaaaacg cctgcaagtt ggctacaagg aagacgatat tcgtgccttc
    30301 ctaccacgct ctgtccgtaa tgtagaaaat gcagaagcac gtttacgtgc agctctataa
    30361 acatcaaggc tgggagcaat tcccagtctt attctatttt aatttcaaaa agaaagaaga
    30421 aagaaatgaa aaaaatagtt cttgttagtc tagctttcct ttttgtcctg gttggttgcg
    30481 gacagaaaaa agaaactgga ccagctacaa aaacagaaaa ggatacgctt cagtcggcat
    30541 tgccagttat tgaaaatgcc gagaagaata cagttgtaac caagactttg gtcttgccca
    30601 agtcagatga tggtagccag caaactcaaa ccattacata caaggacaag acttttttga
    30661 gcttaacgat tcaacaaaaa cgtccagttt ctgatgagtt gaagacttat attgaccaac
    30721 atggagtgga agaaactcaa aaagctcttc ttgaagcgga ggagaaggat aagtctatca
    30781 ttgaagctcg taaattggta ggtttcaaac ttgaaacaaa actattgagc gcaacggaac
    30841 ttcaaacaac gactagtttt gattttcaag ttctggatgt caagaaggct tcccagttgg
    30901 aacatctgaa gaatattggt ttggaaaatc ttttgaaaaa tgaaccaagc aaatatattt
    30961 cagacagatt ggcaaatggt gcgacagaac agtagaaaat ccaaataaat agactgcctg
    31021 aattgtagaa ggtaaggaat tatgctataa tggtactatt ctaaggaaag agggtgttag
    31081 aatgggattt actgaagaaa cagtacgttt taaattggac gattccaata aaaaagaaat
    31141 tagcgaaact ttgacagatg tttatgcttc gttgaacgat aagggttaca acccaattaa
    31201 ccaaatcgta ggttacgtat tgagtggaga ccctgcctac gttcctcgtt ataataatgc
    31261 acgaaatcaa atccgtaagt atgagcgtga tgaaatcgtt gaggaattgg ttcgctacta
    31321 cctcaaagga caaggagtcg atctataacc tatgagaatt atgggattgg acgtcggttc
    31381 aaaaacggta ggggtggcga ttagcgatcc gcttggtttt acagctcaag ggcttgaaat
    31441 catccagata aatgaagaac aaggccaatt tggttttgac cgcgttaagg aattggttga
    31501 tacttacaag gtggaacgat ttgtagtggg cttgcctaaa aacatgaaca atacaagtgg
    31561 accgcgcgta gaagctagtc aagcctacgg agcaaagcta gaagagtttt ttggtttacc
    31621 agtagactat caggatgaac gcttgacaac agtggctgct gagcgcatgt tgattgaaca
    31681 agcagatatc agtcgcaata agcgcaagaa agtcattgat aagttagcag ctcagctgat
    31741 tttacaaaat tatttagata gaaaatttta atataaagga gaggctatgt cacacgatca
    31801 taaccacgac cacgaagaac gtgaactaat cacactagta gatgagcaag gaaatgaaac
    31861 cttgtttgaa atccttttga caattgatgg aaaagaagaa tttggtaaaa actatgttct
    31921 tctagtacca gttaacgcag aagaagacga agacggacaa gttgaaatcc aagcttactc
    31981 attcatcgaa aacgaagatg gaacagaagg cgaattgcaa ccaatcccag aagactcaga
    32041 agacgaatgg aacatgattg aagaagtctt caacagcttt atggaggagt gatacagtct
    32101 gggagactgt atcagcccaa ctcccagaaa tggggaagag ttggaacatc cagtggatgt
    32161 ttttagccca gttcctttaa ataagagaga actggtaagt ccgggggacg tttttagcct
    32221 gacgctaaaa ataaaaacag tcagtaagtt cgggggatgt tttagcccag ctccttgaaa
    32281 taagatagag ctggtaagtc tgagaaactg tatcagccca actcccagaa atggggaaga
    32341 gttggaacgt ccagtgaaca tttttacccc aactcttaga aattgagaag agttggaaca
    32401 tctagtggat gtttttagcc catattcaca ttcatagtag ctagttatta gctaaccagg
    32461 taagaggtcg ggacgaaaat cctggccttg tttttattag taaccatact ttaatgcgat
    32521 aattgattgg acttttgtca aggagatgtg tatgtttgaa gtagaagaat ggctccatag
    32581 tcggattggt ttgaattttc gatcaggttt gggccgaatg cagcaagcgg tggatttgtt
    32641 aggaaatcct gagcagtctt accctattat ccacgtaaca gggactaatg ggaaaggatc
    32701 taccattgct tttatgaggg aattatttat ggggcatggc aaaaaagttg cgacctttac
    32761 ctcccctcat atcgtctcta tcaatgaccg aatctgcatt aatgggcaac ctatagcaga
    32821 cgcagacttt atccgtttga ctgatcaggt caaggagatg gagaaaacgc ttctgcaaac
    32881 tcctgcccag ttgtcctttt ttgaattgct gaccttagtt gcttttcttt attttaggga
    32941 gcaagaggtg gatttggttt tattagaagt gggaattggt ggcttacttg acacgaccaa
    33001 tgtggtaact ggagagcttg ctgtcatcac ctccattggg cttgaccatc aagaaacctt
    33061 gggtgatagt ctagaagcaa ttgcagagca gaaagctggt attttcaagg ctggtaaaaa
    33121 ggcagtgatt gcgaaattgc ctccagaagc tagacttgtc tgtcagaaaa aagctgaatc
    33181 tttagctgtt gacctttatc aggcaggtca agatttttca gtgctgaatg gtgatttttc
    33241 aagctcttta ctaaatcttt cacagctgaa cataggctta gaaggagcct atcagcagga
    33301 gaatgcggcc ttggcgttgc aaacttttct tctttttatg ggagaaagaa aggaagctat
    33361 tgatgaacag gctgtaagaa aggccttgga acagacccat tgggctggtc gcttggagcg
    33421 tattcgccca cagatttact tggatggtgc tcataacctc cctgccttga ctcgcttggt
    33481 tgagtttatc aaagaaaaag agcaggaagg ctatcgacct caaatcctct ttggatcctt
    33541 gaaacgtaag gattatcaag ggatgttggg ttatctgact gaaaatttac ctcaagtgga
    33601 actcaaaatg accggctttg actatcaagg gtctttggac gagacagatg taacaggtta
    33661 ccatgtaatt ccctcttacc gagaatttat cagcagtttc gaagaaaggg cagacgctca
    33721 agacttgctg ttcgttacag ggtctctcta ttttatctca gaagtacggg gctacctgct
    33781 ggaccgtgag cagataaatt gacccccttg tttgaacttg ttatactagg ggaattgctg
    33841 gttagagaaa atttctctaa attggtagca gaaaggaaat tcatcatgaa attaaaaaga
    33901 ttcacacttt ctcttgcttc tctagcaagt tttagtctct tagtagcttg ttcacaaaga
    33961 gctcaacagg ttcaacagcc tgttgctcag cagcaggtcc aacagcctgc tcaacagaat
    34021 accaatactg caaatgcagg aggtaaccaa aatcaagcgg ctccagtaca aaaccaacct
    34081 gttgctcaac cgaccgatat tgatgggact tatactggtc aggatgacgg agaccgtatc
    34141 actttagtgg taactggaac gactggtaca tggactgagc tcgaatctga cggggatcag
    34201 aaagtcaaac aggttacatt tgattcagca aatcaacgca tgattattgg cgatgatgtc
    34261 aaaatttaca ctgtaaacgg taatcaaatc gtcgtagatg atatggatag agacccatcg
    34321 gaccaaatcg ttttaactaa ataagactat gcaagtagaa agggctggat ttttcagcct
    34381 ttttactttt acctagaaaa taatcataaa tacttgcctt ctaccgaata cctgcgttat
    34441 actagtatca attacttgtt tttagcattc aaactatcaa ggaggggata tgaaatatag
    34501 gaaatttcaa ttattgatgt ccaagtatgg ctttagtctt tcgattatgc tacttgaact
    34561 ttgtcttgtt tttggtctct ttctttattt aggacgcatg gctcccattt tatggattac
    34621 tgtcctcatt ctactgagta tcatcacaat catttcgata gtcaaccgta atacgactcc
    34681 tgagaataag gtaacctggt tgttagtagc ctttgtgcca gtatttggtc ccttgctcta
    34741 tctgatgttt ggtgaaaggc gattgtccaa aaaagaaatc aaacaactga agaagctagg
    34801 ctctatgcat ttccaagaag caaatagcca gctactaaaa gagaaattaa aagaaagtga
    34861 caaggcagct tatggagtca tcaagtcctt attgagtatg gataccaatg ctgacatcta
    34921 tgatcaaact gcctctacat tttttcctaa cggagaagct atgtggaaaa agatggtaga
    34981 agatcttaaa aaggctgaga aatttatttt cttggaatat tacattatag aagaaggttt
    35041 gatgtggaat cgcatactag atatactaga gcaaaaggta gctcagggtg tagaggttaa
    35101 gatgctctat gatgatatcg gctgtatggc tactttaaca ggagattatg cacatcgact
    35161 tcgtcagctg ggcatcgagg cccataaatt caataaagtt attcctcgtt tgacagtggc
    35221 ttataataac agagatcata gaaaaatatt gattgttgat ggtcagatag cctatactgg
    35281 tggggtcaat ctggcagatg agtacattaa ccacgtcgag agatttggtt attggaagga
    35341 tagtggaatt cgcttagacg gactagcagt aaaagctctg acacgcttat ttttgaccac
    35401 ttggtacatt aatcgaggag aaattagtga ttttgatcaa tatcatttag aaaatcattc
    35461 tatcccgagt gacggtttaa ccattccata cggaagtgga cccaagccaa tttttcgagc
    35521 gcaggtaggg aaaaaagttt atcagagttt aatcaatcaa gcaacagaat cggtctatat
    35581 tacgacacct tatttgatta tagattatga tttaacagag acaatcaaaa atgcagctat
    35641 gagaggggtc gatgttcgaa ttatcacccc ttacatacca gataagaagt tcattcagtt
    35701 agtcacgaga ggagcttatc ccgaccttct ttctgctggt gttcggattt atgagtatag
    35761 tccaggtttt attcatagta agcagatgtt ggtagacgaa gattttgcgg tggtggggac
    35821 aatcaatctc gactaccgga gcttggtaca ccattatgaa aatgcagtct tactctataa
    35881 aactccttct ataagggaaa tcgcccgaga ttttcgaaat atatttgcag attctcagga
    35941 agtctatcct cattctatca aaacgagctg gtatcaaaag cttgtaaaag aaatcgccca
    36001 gctattcgcc cctatcttat aagaaatcta gaacttagga tacaaaccag acctattttt
    36061 cttgtctttt acgaatagaa agaaagagga ggggaattca tgctaactaa ggaagaagtg
    36121 aatgatatga ttgagttcaa acagacacat ttacaccgct ttcgggaaat tgaaaccttt
    36181 gtgaaactat gcaaaaaatc actcaaacag ccatcgcaag ctgacaatcc taggactttt
    36241 tgatatacta agacagataa attgaacagg agaaacgata tgagtgtgta tggtagagta
    36301 gaagaagttc ataaggagaa tcgtgaacct ctagaatacc aaatcgaaca agaatcgcat
    36361 catcgtgaat caagtcgtct tcctttggtg aaaattttac tatggagtac gcttgtaacg
    36421 gggataactc taggagtacc gctattactc gacttaatga gtgcacaaga agtgcaggat
    36481 ttttatgcag gttgggcgct tcatcagaca gggaagattt acagcgacta ttatggaagt
    36541 caaggtttgc tttattattt gctgacttac gtgagtcagg gcggattttt ctttgccatc
    36601 tttgagtggt tagccttggt agcaggagga tttttccttt ttagatcagc ggacaccttg
    36661 acagagcaag gagaccaagc tggacatctg gtgactattt tttacatgct agttacaggt
    36721 cttgcttttg gtggaggcta tgcgactctt ttagcgcttc ctttcttatt cgcagccttt
    36781 agtttagttg cggcttacct aagcaatcca agccatgata agggatttgt acggattggg
    36841 ctagctttgg caggcggatt tttctttgct cccttatcat cgctcctgtt tattgctgta
    36901 gtgagtttag gcttgttggt ctttaacctt gggcatagac gctttgcgca tgggttttat
    36961 cagtttcttg cagtggcttt aggtttttca cttgtctttt atccaactgc ctactatagt
    37021 gctgcaacag gaagttttgg ggatgcgatt agtggtattc gttatcctat tgacagtatt
    37081 cgctttgatt ttacttctaa aattttagag aatatgtttt tttatggctt gttgtccctt
    37141 ggtttgggat ttgtggtttg tatcttttta ggtctctttc aatccaaacc ctttaaacta
    37201 tacgtcattt cggttcctgc aagtcttgtg gtaattttag gtttgatttt acttttcttt
    37261 tcacaagagc ctctgcacgc ttcttatttg atggacgtct tccctgtttt cctactttta
    37321 ttggtaacca atattaagag tcaacagagg gggcgtagtg ctagaagaag ccgaagagaa
    37381 acgccagtta gcctatggag tcgtttcttc aaaggaaatc tatatctgct agtttttggg
    37441 tttgtctatc ttttgtctgt tccttttttg atgaagtttg tcctttatcc agtaccttat
    37501 caagaacgta atcgtcttgc tgatttggta aaagaggaga caaatacgga agatgctatc
    37561 tatgcatggg atgatactgc gactctttat cgtaagagtg agcgcttgtc gccatcggcg
    37621 attttgtccc cgttgcacta tacagcaact gaggaaaatc gtaataagtt acttaatgac
    37681 ttgaaagaaa aacaacctaa ggtgattgtg gtaaatgaca aggtggtagt ctggtctgaa
    37741 gtggaaacac tcttaaaaga aaattaccaa caagtaaaga ctgattactc agagtttaaa
    37801 gtctataaaa ttaaataacc aaatcaatat cttgtgtatt tttaaaaatt ttaggatttt
    37861 taacacaaga tattgatttt tctttttaga gtggtataat actttttaga aagaacattt
    37921 tagaaaagag catgcgtatg attgcactag aagaaaaaat tacaattttg ccaactctct
    37981 tcgtcgagaa acgagatggg agacgtgttg tatttgatgt ggacaagatt gacaaggctc
    38041 tccacaaggc ggctgacaag gttatggatg tgacacccct ggttgaaaaa cgcctcaatg
    38101 atctgactga gcgaattatt acagaaattc atagtcgctt tccacaggga attaagattt
    38161 acgaaattca aaatatcgta gaacatgaac tccttgaagc caaagaatat gcactggctg
    38221 aggagtatat tacttatcgg acacagaggg attttgagcg ctcaaaagcg acggatatca
    38281 actttagtat tcataaactt ctcaacaaag accagacagt tgtcaatgaa aatgctaata
    38341 aagacagtga tgtctttaac actcagcgtg atttgacagc agggattgtt gggaaatcaa
    38401 tcggactgca aatgcttcct aagcacgtag ccaatgccca ccaaaagggg gatatccact
    38461 atcacgattt ggactacagt ccctataccc ctatgaccaa ctgctgtttg attgatttta
    38521 agggtatgtt ggaaaatggt tttaagattg gaaatgcaga ggtagagagt cccaagtcta
    38581 tccagactgc gacagcacag atttctcaaa tcattgccaa cgttgcttct agccagtacg
    38641 gtggctgttc agctgaccgt atcgatgaaa ttttggcgcc ttatgcagag aagaactatc
    38701 aaaaacatct caaagatgca gaagagtggg tattgcctga aaaacgggaa gattacgctt
    38761 ggaagaaaac gcaaaaggac atctacgatg ccatgcaatc tcttgagtat gaaatcaata
    38821 ctctcttcac ttcaaatgga caaacacctt ttacttcgct aggttttggt ctgggaacca
    38881 gtcgttttga acgagaaatt caaaaagcta ttttaaacat tcgcatcaag ggtcttggtt
    38941 cagaacaccg tacggctatc tttcctaaac ttattttcac tctgaaaaga ggacttaatt
    39001 tagaggaagg aactcccaac tacgacatca agcagttggc tcttgagtgt gcaaccaaac
    39061 ggatgtatcc agatgtttta tcttacgata agattgttga cttgacagga tccttcaagg
    39121 tgcctatggg ttgccgttct ttcctccaag gatggaaggg tgaaaatggt gtagaagtca
    39181 attcaggtcg catgaatctg ggtgttgtga cggttaatct gcctcgtatc gctcttgagt
    39241 ctgaaggtga tatgaataag ttctgggaaa tcttcaacga gcgaatgaat atcgcagaag
    39301 atgctcttgt ttaccgtgtc gaacgcacta aagaggcgac accagcaaat gctcctattc
    39361 tttatcagta tggtgctttt ggccatcgtc taggtaaaga agaaagtgtt gaccagctct
    39421 ttaagaatcg tcgtgcgacc gtttcgctgg gctatatcgg cttgtatgaa gtagcgacag
    39481 ttttctttgg taacagctgg gaaagtaatc cagatgctaa ggaattcacg ctagacatca
    39541 ttcacgatat gaaacgccgt gtagaagagt ggtcagacca atatggctac catttctcta
    39601 tctactcaac accatccgaa agtctgacag accgtttctg ccgactagat atagacaagt
    39661 ttggctctat tcctgatatc acagacaagg aatactacac caactctttc cactacgatg
    39721 ttcgtaaaaa tccaacaccg tttgaaaaat tggactttga gaaagtctat ccagaagcag
    39781 gtgcgtcagg tggtttcatc cattattgtg agtatccagt ccttcagcaa aatccaaagg
    39841 ccttggaagc tgtctgggat tatgcttatg accgtgtagg ctatctaggc accaatactc
    39901 cgattgaccg ttgctacaag tgtgactttg aaggggattt tgaaccaact gagagagggt
    39961 ttgcttgtcc aaactgtggc aatagcgacc ctaaaacagt agatgtggtg aagcgaactt
    40021 gtggctacct aggtaatcct caagcaagac cgatggtcaa cgggcgtcac aaggaaatcg
    40081 ctgcgcgtgt caaacatatg aatggttcaa cgattaaaat agctgggcat caagtaacaa
    40141 attagaaaga aatgaaatgg gaaaatatca actagacgat aaggggcgcg cacaagtgac
    40201 ccgttatcac gagaaacact ctaaaggtgg agctggtaag aaagaacgct tgcttagctt
    40261 cagagaacaa tttttaaaca agaacaagaa aaaataaaag tgagagccag ctctcgcttt
    40321 tctcatagtg ggaggtaagg atggaattac gcagaccaag attagcggat aagaaagctg
    40381 ttttagatat gatgacagag tttgaaaaat ttcagtcgcc tcacgacggc ggtttatggg
    40441 atacagagaa ctttgtgtat gaagactggt tagaaagcaa tcaggaacag gaaatgggga
    40501 ttaatctgcc tgaaggatgg gttcctgcaa ttcagttagt ggctttttct gagaaaggtc
    40561 aagcagttgg atttcttaat ctccggttgc gcctcagtaa ctttctacta gaagaaggtg
    40621 gccacattgg ctactccatt cgtccatctg aaagaggcaa gggttatgca aaagagactc
    40681 tccgtcaggg cttgcaagtt gctaaggaaa agaacatcaa gaaagctctg gtgacctgta
    40741 gcgtgaataa tcctgctagc agagcagtca ttctagcaaa tggtggaata tttgaggatg
    40801 ctcgcaatgg agtcaagcgt tattggatag aggtagcgaa tgaataatcc aaaaccacaa
    40861 gaatggaaaa gcgaggaact tagtcaaggt cgtatcattg actacaaggc ctttaacttt
    40921 gtggacggcg aaggcgtgcg taactctctc tatgtatcag gctgtatgtt tcactgcgag
    40981 ggatgttata atgtagcgac ctggtccttc aatgcaggca ttccctatac agctgagttg
    41041 gaagaacaga ttatggcaga tcttgcccag ccttatgttc aggggttaac cttactagga
    41101 ggggagcctt ttcttaatac tgggattctc ttgccacttg ttaagcggat tcggaaggaa
    41161 ttgccagaca aggacatctg gtcctggacg ggctacactt gggaagaaat gatgttggaa
    41221 actccagata aactggaact cttgtcactg attgacattc ttgtcgatgg aagatatgat
    41281 cgaactaaga gaaatcttat gctccagttt cgaggttcgt ccaaccaacg aattatcgat
    41341 gtgcaaaaat cgctcaaaag tgggcaagta gtgatttggg acaagctcaa tgacggaaaa
    41401 gaaagctatg aacaggtgaa gagagaatga agaaaaaaga cttagtagac caactagtct
    41461 cagagatcga gacggggaaa gtcaggacac tgggaatata cggtcatgga gcttcaggta
    41521 aatcaacctt tgcacaggaa ttgtaccaag ctttagattc tactacagta aatttgctag
    41581 agacagatcc ttatatcacc tcaggacgcc atctggtagt acccaaggac gcgccgaatc
    41641 aaaaggtgac agccagtctg ccagtggcgc atgaactgga gagtttgcag agagatatcc
    41701 ttgccttgca ggcgagtatg gatgtcttga caattgaaga accttggaag gctagtgagg
    41761 ttttgtctgg agccaaacca attttgattg tcgaagggat gtctgttggc tttctaccca
    41821 aggaactctt tgaaaaaacc atctgtttct acacggatga ggagaccgaa ttaaagcgac
    41881 gccttgctag agatacgact gtgagaaatc gcgatgcatc ctttatattg gctagccatc
    41941 agatgagacg ggagcagtat ctgcgatact ataaagaaac tgagtctaag gcggatatct
    42001 tagtggacca atcagaagat aaatttgatg tcaagaggac ttaacttatg tatagaagaa
    42061 atatagaaga aaatccctaa ttttagaaag aaaaagtagg aaaacagttt catcccaaaa
    42121 aaacgaaaaa acagcaacaa atcccttgca atcgcagggg ctttgtgtta ttctattatg
    42181 gtgctgtaaa ttacagcctt agttttgatg caagaggttg cgacacgctc ggttgcattg
    42241 ccacgcaaca ccgcgtcggt tttcttgtgg agctagccta ttatcttaaa tagacgaaaa
    42301 ggagaaaaag atggcaaaca aaaaaatccg tatccgtttg aaagcttacg aacaccgtac
    42361 gcttgacaca gcggctgcaa aaatcgtaga atcagctact cgtacaggtg cacaagttgc
    42421 gggtccaatc ccacttccaa ctgaacgtag cctctacaca atcattcgtg cgactcacaa
    42481 atacaaagac tctcgcgaac aatttgaaat gcgtacacac aaacgtttga tcgatatcgt
    42541 taacccaact caaaaaacag ttgatgcctt gatgaaattg gatcttccaa gtggtgtaaa
    42601 cgtagaaatc aaactttaat ctaaaatata aaagagcaga ggctggtgtt tcaatctaat
    42661 tgaacacggg ctaaactcgg tgtgaaaaag ataaacttcc tagtgtctgc tagacactgc
    42721 gtcagtttcc tattttgacg ttgagtttga cgtcctttgt atcttagact tgagcataaa
    42781 aaacgctcgt taaaaacttt ttgaataaaa atatagaaaa ggaactattt tctcatgaca
    42841 aaaggaatct tagggaaaaa agtgggaatg actcaaatct tcactgaagc tggcgaattg
    42901 atccctgtaa cagttattga agcaactcca aacgttgttc ttcaagttaa aactgttgaa
    42961 acagacggat acaacgctat ccaagttggt ttcgatgaca aacgcgaagt attgagcaac
    43021 aaacctgcta aaggacatgt agcgaaagct aacacggctc ctaagcgctt cattcgtgaa
    43081 ttcaaaaacg ttgaaggctt ggaagttggc gctgaaatca cagttgaaac attcgcagct
    43141 ggagatgttg ttgacgtaac gggtacttct aaaggtaaag gtttccaagg tgttatcaaa
    43201 cgccacggac aatcacgtgg accaatggct cacggttctc gttaccaccg tcgtccaggt
    43261 tctatggggc ctgttgcacc taaccgcgta ttcaaaggta aaaaccttgc aggacgtatg
    43321 ggtggcgacc gcgtaacaat tcaaaacctt gaagttgtac aagttgttcc agaaaagaac
    43381 gttatcctta tcaaaggtaa cgtaccaggt gctaagaaat ctcttatcac tatcaaatca
    43441 gcagttaaag ctggtaaata ataaagaaag gggaaatcag tcacaatggc aaacgtaaca
    43501 ttatttgacc aaactggtaa agaagctggc caagttgttc ttagcgatgc agtatttggt
    43561 atcgaaccaa atgaatcagt tgtgtttgat gtaatcatca gccaacgcgc aagccttcgt
    43621 caaggaacac acgctgttaa aaaccgctct gcagtatcag gtggtggacg caaaccatgg
    43681 cgtcaaaaag gaactggacg tgctcgtcaa ggttctatcc gctcaccaca atggcgtggt
    43741 ggtggtgttg tcttcggacc aactccacgt tcatacggct acaaacttcc acaaaaagtt
    43801 cgtcgcctag ctcttaaatc agtttactct gaaaaagttg ctgaaaacaa attcgtagct
    43861 gtagacgctc tttcatttac agctccaaaa actgctgaat ttgcaaaagt tcttgcagca
    43921 ttgagcatcg attctaaagt tcttgttatc cttgaagaag gaaatgaatt cgcagctctt
    43981 tcagctcgta accttccaaa cgtgaaagtt gcaactgcta caactgcaag tgttcttgac
    44041 atcgcaaata gcgacaaact tcttgtcaca caagcagcta tctctaaaat cgaggaggtt
    44101 cttgcataat gaatttgtat gatgttatca aaaaacctgt catcactgaa agctcaatgg
    44161 ctcaacttga agcaggaaaa tatgtatttg aagttgacac tcgtgcacac aaacttttga
    44221 tcaagcaagc tgttgaagct gctttcgaag gtgttaaagt tgccaatgtt aacacaatca
    44281 acgtaaaacc aaaagctaaa cgtgttggac gttacactgg ttttactaac aaaactaaaa
    44341 aagctatcat cacacttaca gctgattcaa aagcaatcga gttgtttgct gctgaagctg
    44401 aataatctaa ggaggaaata tcgtgggaat tcgtgtttat aaaccaacaa caaacggtcg
    44461 ccgtaatatg acttctttgg atttcgctga aatcacaaca agcactcctg aaaaatcatt
    44521 gcttgttgca ttgaagagca aggctggtcg taacaacaac ggtcgtatca cagttcgtca
    44581 ccaaggtggt ggacacaaac gtttctaccg tttggttgac ttcaaacgta ataaagacaa
    44641 cgttgaagca gttgttaaaa caatcgagta cgatccaaac cgttctgcaa acatcgctct
    44701 tgtacactac actgacggtg tgaaagcata catcatcgct ccaaaaggtc ttgaagtagg
    44761 tcaacgtatc gtttcaggtc cagaagcaga tatcaaagtc ggaaacgctc ttccacttgc
    44821 taacatccca gttggtactt tgattcacaa catcgagttg aaaccaggtc gtggtggtga
    44881 attggtacgt gctgctggtg catctgctca agtattgggt tctgaaggta aatatgttct
    44941 tgttcgtctt caatcaggtg aagttcgtat gattcttgga acttgccgtg ctacagttgg
    45001 tgttgtcgga aacgaacaac atggacttgt aaaccttggt aaagcaggac gtagccgttg
    45061 gaaaggtatc cgcccaacag ttcgtggttc tgtaatgaac cctaacgatc acccacacgg
    45121 tggtggtgaa ggtaaagcac cagttggtcg taaagcacca tctactccat ggggcaaacc
    45181 tgctcttggt cttaaaactc gtaacaagaa agcgaaatct gacaaactta tcgttcgtcg
    45241 tcgcaacgag aaataatatt aaactagtcg cttaagcaac tagtaaatcc gccagctcgg
    45301 tagcgctcca taggagtgca agccgctgtg gtacaacatt taaaggagaa aatataaaaa
    45361 tgggacgcag tcttaaaaaa ggacctttcg tcgatgagca tttgatgaaa aaagttgaag
    45421 ctcaagctaa cgacgaaaag aaaaaagtta ttaaaacttg gtcacgtcgt tcaacgatct
    45481 tcccaagttt cattggttac actattgcag tttatgacgg acgtaaacac gtacctgttt
    45541 acatccaaga agacatggta ggccacaaac ttggtgaatt tgcaccaact cgtacttaca
    45601 aaggtcacgc tgcagacgac aagaaaacac gtagaaaata aggagaacat aaatggcaga
    45661 aattacttca gctaaagcaa tggctcgtac agtacgtgtt tcacctcgta aatcacgtct
    45721 tgttcttgat aacatccgtg gtaaaagcgt agccgatgca atcgcaatct tgacattcac
    45781 tccaaacaaa gctgctgaaa tcatcttgaa agttttgaac tcagctgtag ctaacgctga
    45841 aaacaacttt ggtttggata aagctaactt ggtagtatct gaagcattcg caaacgaagg
    45901 accaactatg aaacgtttcc gtccacgtgc gaaaggttca gcttcaccaa tcaacaaacg
    45961 tacagctcac atcactgtag ctgttgcaga aaaataagga ggtaaaatcg tgggtcaaaa
    46021 agtacatcca attggtatgc gtgtcggcat catccgtgat tgggatgcca aatggtatgc
    46081 tgaaaaagaa tacgcggatt accttcatga agatcttgca atccgtaaat tcgttcaaaa
    46141 agaacttgct gacgcagcag tttcaactat tgaaatcgaa cgcgcagtaa acaaagttaa
    46201 cgtttcactt cacactgcta aaccaggtat ggttatcggt aaaggtggtg ctaacgttga
    46261 tgcactccgt gcaaaactta acaaattgac tggaaaacaa gtacacatca acatcatcga
    46321 aatcaaacaa cctgatttgg atgctcacct tgtaggtgaa ggaattgctc gtcaattgga
    46381 gcaacgtgtt gctttccgtc gtgcacaaaa acaagcaatc caacgtgcaa tgcgtgctgg
    46441 agctaaagga atcaaaactc aagtatcagg tcgtttgaac ggtgcagata tcgcccgtgc
    46501 tgaaggatac tctgaaggaa ctgttccgct tcacacactt cgtgcagata tcgattacgc
    46561 ttgggaagaa gcagatacta catacggtaa acttggtgtt aaagtatgga tctaccgtgg
    46621 tgaagttctt ccagctcgta aaaacactaa aggaggtaaa taaccaatgt tagtacctaa
    46681 acgtgttaaa caccgtcgtg agttccgtgg aaaaatgcgc ggtgaagcaa aaggtggaaa
    46741 agaagtagca ttcggtgaat acggtcttca agctacaact agccactgga tcactaaccg
    46801 ccaaatcgaa gctgctcgta tcgccatgac tcgttacatg aaacgtggtg gtaaagtttg
    46861 gattaaaatc ttcccacaca aatcatacac tgctaaagct atcggtgtgc gtatgggatc
    46921 tggtaaaggg gcacctgaag gttgggtagc accagttaaa cgtggtaaag tgatgttcga
    46981 aatcgctggt gtatctgaag agattgcacg tgaagcgctt cgacttgcta gccacaaatt
    47041 gccagttaaa tgtaaattcg taaaacgtga agcagaataa ggagaaggca tgaaacttaa
    47101 tgaagtaaaa gaatttgtta aagaacttcg tggtctttct caagaagaac tcgcgaagcg
    47161 cgaaaacgaa ttgaaaaaag aattgtttga acttcgtttc caagctgcta ctggtcaatt
    47221 ggaacaaaca gctcgcttga aagaagttaa aaaacaaatc gctcgtatca aaacagttca
    47281 atctgaagcg aaataataga ctagggaagg agaaatttca atggaacgca ataatcgtaa
    47341 agttcttgtt ggacgtgttg tatctgacaa aatggacaag acaatcacag ttgtagttga
    47401 aacaaaacgt aaccacccag tctatggtaa acgtattaac tactctaaaa aatacaaagc
    47461 tcatgatgaa aacaatgttg ccaaagaagg cgatatcgta cgtatcatgg aaactcgccc
    47521 gctttcagct acaaaacgtt tccgtcttgt agaagttgtt gaagaagcgg tcatcatcta
    47581 atcaaacctg aaaggagaaa actgaaatga ttcaaacaga aactcgtttg aaagtcgcag
    47641 acaacagcgg tgctcgcgaa atcttgacta tcaaagttct tggtggttca ggacgtaaat
    47701 ttgcaaacat cggtgatgtt atcgtggcat ctgtaaaaca agctactcct ggtggtgcgg
    47761 ttaaaaaagg tgacgttgtt aaagcagtta tcgttcgtac taaatcaggt gctcgtcgtg
    47821 ctgatggttc atacatcaaa tttgacgaaa acgcagcagt tatcatccgt gaagacaaaa
    47881 ctcctcgcgg aacacgtatc tttggcccag ttgcacgtga attgcgtgaa ggtggtttca
    47941 tgaagatcgt gtcacttgct ccagaagtac tttaattttt aggaacaaac tagtccccta
    48001 gcttcaagct agggtgccct tatgggcgta agaaaaatca aggagaaacc taatgtttgt
    48061 aaaaaaaggc gacaaagttc gcgtaatcgc tggtaaagat aagggaacag aagctgttgt
    48121 ccttactgcc cttccaaaag taaacaaagt tatcgttgaa ggtgttaaca ttgttaagaa
    48181 acaccaacgt ccaactaacg agcttcctca aggtggtatc atcgagaaag aagcagctat
    48241 ccacgtatca aatgttcaag ttttggacaa aaatggtgta gctggtcgtg ttggttacaa
    48301 atttgtagac ggtaaaaaag ttcgctacaa caaaaaatca ggcgaagtgc ttgattaatc
    48361 acgaaggaaa ggagaagtat aatggcaaat cgtttaaaag aaaaatatct taatgaagta
    48421 gttcctgctt tgacagaaca attcaactac tcatcagtga tggctgtgcc taaagtagat
    48481 aagattgttt tgaacatggg tgttggtgaa gctgtatcaa acgctaaaag ccttgaaaaa
    48541 gctgctgaag aattggcact tatctcaggt caaaaaccac ttatcactaa agctaaaaaa
    48601 tcaatcgccg gcttccgtct tcgtgaaggt gttgcgatcg gtgcaaaagt tacccttcgt
    48661 ggtgaacgta tgtacgaatt cttggataaa ttggtatcag tttcacttcc acgtgtacgt
    48721 gacttccacg gtgtcccaac aaaatcattt gatggacgcg ggaactacac acttggtgtg
    48781 aaagaacaat taatcttccc agaaatcaac ttcgatgacg ttgacaaaac tcgtggtctt
    48841 gacatcgtta tcgtaacaac tgctaacact gacgaagagt cacgtgcatt gcttacaggc
    48901 cttggaatgc cttttgcaaa ataatatagg aggtaaatct aatggctaaa aaatcaatgg
    48961 tagctagaga ggctaaacgc caaaaaattg ttgaccgtta tgctgaaaaa cgtgctgcat
    49021 taaaggcggc aggggactac gaaggtttat ctaaattacc tcgcaacgcc tcaccgactc
    49081 gtttacataa tcgttgtagg gttacggggc gcccacattc agtttaccgc aaatttggtc
    49141 tgagtcgtat cgcttttcgc gaacttgcgc ataaaggtca aattcctggt gtaacaaaag
    49201 catcttggta atttaagata tcaagagcgt caaaactcca agtaaaaata ggaaacttga
    49261 cgaagaaact aaagtttcta ggaaagttta tctttttcac acagagttta gcccgtgttc
    49321 aattgggctt gccaatttga acacgagcta cagctttggc aaaaaagacc aatttgcttt
    49381 ggagcattgc ttctgcatta aattgtctat ttttgctcgt gctgttacgc tctttgtatc
    49441 atgtattaac tagcaagtgc aacttgcaaa ctactagtaa gaggagaaaa acaaaatggt
    49501 tatgactgac ccaatcgcag acttcctaac tcgtattcgt aatgctaacc aagctaaaca
    49561 cgaagtactt gaagtacctg catcaaacat caaaaaaggg attgctgaaa tccttaaacg
    49621 cgaaggtttt gtaaaaaacg ttgaaatcat tgaagatgac aaacaaggcg tcatccgtgt
    49681 atttcttaaa tacggaccaa atggtgagaa agttatcact aacttgaaac gtgtttctaa
    49741 accaggactt cgtgtctaca aaaaacgtga agaccttcca aaagttctta acggacttgg
    49801 aattgccatc ctttcaactt ctgaaggttt gcttactgat aaagaagcac gccaaaagaa
    49861 tgttggtggt gaggttatcg cttacgtttg gtaaaatcaa gatacaaagc tcgtaaagaa
    49921 caaagcaaaa ttaggaagtt ggagaagttt gtttacaaac aagccaactt atctattttg
    49981 cacagttctt agagcgtgtt cagttcagct cttgaactaa ataagtatct gaaccccgtg
    50041 aaaactggcc gttctggcct gacaatctaa caggagaaaa taaacatgtc acgtattggt
    50101 aataaagtta tcgtgttgcc tgctggtgtt gaactcgcta acaatgacaa cgttgtaact
    50161 gtaaaaggac ctaaaggaga acttactcgt gagttctcaa aagatattga aatccgtgtg
    50221 gaaggtactg aaataactct tcaccgtcca aacgattcaa aagaaatgaa aactatccac
    50281 ggaactactc gtgccctttt gaacaacatg gttgttggtg tatcagaagg attcaagaaa
    50341 gaacttgaaa tgcgtggggt tggttaccgt gcacagcttc aaggatctaa acttgttttg
    50401 gctgttggta aatctcatcc agacgaagtt gaagctccag aaggaattac ttttgaactt
    50461 ccaaacccaa caacaatcgt tgttagcgga atttcaaaag aagtagttgg tcaaacagct
    50521 gcttacgtac gtagccttcg ttcaccagaa ccatataaag gtaaaggtat ccgttacgtt
    50581 ggtgaattcg ttcgccgtaa agaaggtaaa acaggtaaat aatgttgagt ggttgatcat
    50641 caaccaccaa cctattttcc aactttgtgc atagcacacg atttaaaact aaagaggtga
    50701 aaactgtgat ttcaaaacca gataaaaaca aactccgcca aaaacgccac cgtcgcgttc
    50761 gcggaaaact ctctggaact gctgatcgcc cacgtttgaa cgtattccgt tctaatacag
    50821 gcatctacgc tcaagtgatt gatgacgtag cgggtgtaac gctcgcaagt gcttcaactc
    50881 ttgataaaga agtttcaaaa ggaactaaaa ctgaacaagc cgttgctgtc ggtaaactcg
    50941 ttgcagaacg tgcaaacgct aaaggtattt cagaagtggt gttcgaccgc ggtggatatc
    51001 tatatcacgg acgtgtgaaa gctttggctg atgcagctcg tgaaaacgga ttgaaattct
    51061 aataggagga cactagaaaa tggcatttaa agacaatgca gttgaattag aagaacgcgt
    51121 agttgctgtc aaccgtgtta caaaagttgt taaaggtgga cgtcgtcttc gtttcgcagc
    51181 tcttgttgtt gttggtgacc acaatggtcg cgtaggattt ggtactggta aagctcaaga
    51241 agttccagaa gcaatccgta aagcagtaga tgatgctaag aaaaacttga tcgaagttcc
    51301 tatggttgga acaacaatcc cacacgaagt tctttcagaa ttcggtggag ctaaagtatt
    51361 gttgaaacct gctgtagaag gttctggagt tgccgctggt ggtgcagttc gtgccgttgt
    51421 ggaattggca ggtgtggcag atattacatc taaatcactt ggttctaaca ctccaatcaa
    51481 cattgttcgt gcaactgttg aaggtttgaa acaattgaaa cgcgctgaag aaattgctgc
    51541 ccttcgtggt atttcagttt ctgatttggc ataagaaagg ggataaaatg gctcaaatta
    51601 aaattacttt gactaagtct ccaatcggac gcattccatc acaacgtaaa actgttgtag
    51661 cacttggact tggcaaattg aacagctctg ttattaaaga agataacgct gctatccgtg
    51721 gtatgatcac agcagtatct cacttagtaa cagttgaaga agtaaactaa tgaagtttta
    51781 ggggatgtgc actgtaccat cccctaaaac tagatatagt catctatgat gacatcgtat
    51841 aggcgagttg atgggggaga caaccttttc tcccttatcg gcgctagcat tttacaaaag
    51901 aggagaaaat aaaaatgaaa cttcatgaat tgaaacctgc agaaggttct cgtaaagtac
    51961 gtaaccgcgt tggtcgtggt acttcatcag gtaacggtaa aacatctggt cgtggtcaaa
    52021 aaggtcaaaa agctcgtagc ggtggcggag ttcgccttgg ttttgaaggt ggacaaactc
    52081 cattgttccg tcgtcttcca aaacgtggat tcactaacat caacgctaaa gaatacgcaa
    52141 ttgtgaacct tgaccaattg aacgtctttg aagatggtgc tgaagtaact ccagttgttc
    52201 ttatcgaagc aggaattgtt aaagctgaaa agtcaggtat taaaattctt ggtaacggtg
    52261 agttgactaa gaaattgact gtgaaagcag ctaaattctc taaatcagct gaagaagcta
    52321 tcactgctaa aggtggttca gtagaagtca tctaagagag gtgacctatg ttttttaaat
    52381 tattaagaga agctcttaaa gtcaagcagg ttcgatcaaa aattttattt acaattttta
    52441 tcgttttggt ctttcgtatc ggaactagca ttacagttcc tggtgtgaat gccaatagct
    52501 tgaatgcttt aagtggatta tccttcttaa acatgttgag cttggtgtcg gggaatgccc
    52561 taaaaaactt ttcgattttt gccctaggag ttagtcccta tatcaccgct tctattgttg
    52621 tccaactctt gcaaatggat attttaccca agtttgtaga gtggggtaaa caaggggaag
    52681 taggtcgaag aaaattgaat caagctactc gttatattgc tctagttctc gcttttgtgc
    52741 aatctatcgg gattacagct ggttttaata ccttggctgg agctcaattg attaaaactg
    52801 ctttaactcc acaagttttt ctgacgattg gtatcatctt aacagctggt agtatgattg
    52861 tcacttggtt gggtgagcaa attacagata agggatacgg aaacggtgtt tccatgatta
    52921 tctttgccgg gattgtttcc tcaattccag agatgattca gggcatctat gtggactact
    52981 ttgtgaacgt cccaagtagc cgtatcactt catctatcat tttcgtaatc attttgatta
    53041 ttactgtatt gttgattatt tactttacaa cttatgttca acaagcagaa tacaaaattc
    53101 caatccaata tactaaggtt gcacaaggtg ctccatctag ctcttacctt ccgttaaagg
    53161 taaatcctgc tggagttatc cctgttatct ttgccagttc gattactgca gcgcctgcgg
    53221 ctattcttca gtttttgagt gccacaggtc atgattgggc ttgggtaagg gtagcacaag
    53281 agatgttggc aactacttct ccaactggta ttgccatgta tgctttgttg attattctct
    53341 ttacattctt ctatacgttt gtacagatta atcctgaaaa agcagcagag agcctacaaa
    53401 agagtggtgc ctatatccat ggagttcgtc ctggtaaagg tacagaagaa tatatgtcta
    53461 aacttcttcg tcgtcttgca actgttggtt ccctcttcct tggtgtgatt tccattttac
    53521 cgattgcagc taaagatgta tttggtcttt ctgatgttgt tgcctttggt ggaacaagtc
    53581 tcttgatcat tatctctaca ggtatcgaag gaatcaagca attggaaggt tacctattga
    53641 aacgtaagta tgttggtttc atggacagaa cagaataaaa gtatttactg aatcagtaaa
    53701 tgctgaggga gtggaggttt aaactctgac atttgtaaga gttggatctc ccctcttcta
    53761 ttttgttttt aaataggggt gaaaagactt tttgcttcta tttaaaaata aaataaggag
    53821 atcaaatcat gaatcttttg attatgggct tacctggtgc aggtaaggga actcaagcag
    53881 caaaaatcgt agaacaattc catgttgcac atatctcaac aggtgatatg ttccgcgctg
    53941 caatggcaaa tcaaactgaa atgggtgttc ttgctaagtc atatattgac aagggtgaat
    54001 tggttcctga cgaagttaca aatggaatcg taaaagaacg tctttcacaa gatgatatta
    54061 aagaaacagg attcttattg gatggttacc cacgtacaat tgaacaagct catgccttgg
    54121 acaaaacatt ggctgaactt ggcattgaac tagaaggtgt tatcaatatt gaagtgaacc
    54181 ctgacagcct cttggaacgt ttgagtggcc gtatcatcca ccgcgtaact ggagaaactt
    54241 tccacaaggt ctttaaccca ccagttgact ataaagaaga agattattac caacgtgaag
    54301 atgataagcc tgagacagta aaacgtcgtt tggatgttaa tattgctcaa ggagaaccaa
    54361 tcattgctca ctaccgtgcc aaaggtttgg ttcatgacat cgaaggtaat caagatatca
    54421 atgatgtctt ctcagatatt gaaaaagtat tgacaaattt gaaataaagc gtttttcata
    54481 cttgcaaaaa ttcgctacaa atgttatact gaaatagtct gacttataat tgttgtctct
    54541 gtgtctagag gcatcgaatc gaaatttatg gaggtgcttt tgcgtggcaa aagacgatgt
    54601 gattgaagtt gaaggcaaag tagttgatac aatgccgaat gcaatgttta cggttgaact
    54661 tgaaaatgga catcagattt tagcaacagt ttctggtaaa attcgtaaaa actatattcg
    54721 tattttagcg ggagatcgtg ttactgtcga aatgagtcca tatgacttga cacgtggacg
    54781 tatcacttac cgctttaaat aatcgaaaaa cttggaggga taagaaatga aagtaagacc
    54841 atcggtcaaa ccaatttgcg aatactgtaa agttattcgt cgtaatggtc gtgttatggt
    54901 aatttgccca gcaaatccaa aacacaaaca acgtcaagga taagatagaa aggagaaaac
    54961 atggctcgta ttgctggagt tgatattcca aatgacaaac gcgtagtaat ctcattgact
    55021 tatgtttatg gtatcggact tgcaacatct aagaaaattt tggctgctgc tggaatctca
    55081 gaagatgttc gtgtacgtga tcttacatca gatcaagaag atgctatccg tcgtgaagtg
    55141 gatgcaatca aagttgaagg tgaccttcgt cgtgaagtaa acttgaacat caaacgtttg
    55201 atggaaatcg gttcataccg tggtatccgt caccgtcgtg gacttcctgt ccgtggacaa
    55261 aatactaaaa acaacgctcg cactcgtaaa ggtaaagctg ttgcgattgc tggtaagaaa
    55321 aaataatata ggaggtaaaa gtcttggcta aaccaacacg taaacgtcgt gtgaaaaaga
    55381 atatcgaatc tggtattgct catattcacg ctacatttaa taacactatt gttatgatta
    55441 ctgatgtgca tggtaatgca attgcttggt catcagctgg tgctcttggt ttcaaaggtt
    55501 ctcgtaaatc tacaccattc gctgctcaaa tggcttctga agctgctgct aaatctgcac
    55561 aagaacacgg tcttaaatca gttgaagtta ctgtaaaagg tccaggttct ggtcgtgagt
    55621 cagctattcg tgcgcttgct gccgctggtc ttgaagtaac agcaattcgt gatgtgactc
    55681 cagtgccaca caatggtgct cgtcctccaa aacgtcgccg tgtataatca tcgcattaca
    55741 ctgcttttcg tttaagaggg agtaactaaa tgatcgagtt tgaaaaacca aatataacaa
    55801 aaattgatga aaataaagat tatggcaagt ttgtaatcga accacttgaa cgtggctacg
    55861 gtacaactct tggtaactct cttcgtcgtg tacttctagc ttctctacca ggagcagctg
    55921 tgacatctat caacattgat ggtgtgttac atgagtttga cacagttcca ggtgttcgtg
    55981 aagacgtgat gcaaatcatt ctgaacatta aaggaattgc agtgaaatcg tacgttgaag
    56041 acgaaaaaat catcgaactg gatgttgaag gtcctgctga agtaacagct ggtgacattt
    56101 tgacagatag cgatattgaa attgtaaatc cagatcatta tctctttaca attggtgaag
    56161 gttcttctct aaaagcgact atgactgtta acagtggtcg tggatatgta cctgctgatg
    56221 aaaataaaaa ggataatgca ccagttggaa cacttgctgt agattctatt tatacaccag
    56281 ttacaaaagt caactatcaa gtggaacctg ctcgtgtagg tagcaatgat ggtttcgaca
    56341 aattaaccct tgaaatcttg acaaatggaa caattattcc agaagatgct ttagggcttt
    56401 cagcacgtat tttgacagaa catcttgatt tgtttacaaa tcttactgag attgctaagt
    56461 caactgaagt gatgaaagaa gctgatactg aatctgacga ccgtatttta gatcgtacga
    56521 ttgaggaact ggacttgtct gtgcgttcat acaactgttt aaaacgtgcc ggtatcaata
    56581 ctgtgcatga tttgacagaa aaatctgaag cagagatgat gaaagtacga aatcttggac
    56641 gcaagagttt ggaagaagtg aaactcaaac tcattgattt gggtcttgga ttaaaagata
    56701 aataaaggag gaatacatgg cttaccgtaa actaggacgc actagctcac aacgtaaagc
    56761 aatgcttcgc gatttgacaa ctgacctttt gatcaacgaa tcaatcgtga caactgaagc
    56821 tcgtgctaaa gaaatccgta aaactgttga aaaaatgatt actctaggta aacgtggtga
    56881 tttgcatgca cgtcgtcaag cagctgcttt cgtacgtaat gaaatcgcat ctgaaaacta
    56941 tgatgaagca actgataagt acacttctac tacagcactt caaaaattgt tctcagaaat
    57001 cgcacctcgt tatgctgaac gtaacggtgg atacactcgt atccttaaaa ctgaaccacg
    57061 tcgtggtgat gcagcgccaa tggcgatcat cgaattagta taaaatcatc aattttgttg
    57121 agtgttatga tgatggagtc ttgtgctctt agtctagctc tggtctaccg ctaggatttc
    57181 ggtcctagcg ggaacactca tcataagttg ggatagtaga cgcttgttta cgaaattgtt
    57241 tttttcttaa gaacaacttc gtaagcaggc gtttttgagt attttcgtta gaattatgct
    57301 atactatttg aaaagaatcc tgtttaatgt taaggtttct tattttaaga agaattggag
    57361 tttacttatg aaagccatta taactgttgt tggtaaagat aaatctggaa ttgttgcagg
    57421 tgtttctggt aaaattgcag aattaggatt gaatattgac gatatctctc aaactgtctt
    57481 ggatgaatat tttacgatga tggctgttgt atctagtgat gaaaagcaag attttaccta
    57541 tcttcgtaat gaatttgaag cttttgggca aactttgaat gtaaaaatca atattcagag
    57601 tgcagcgatt ttcgaagcta tgtataatat ctaggaggtc atcatggata ttagacaagt
    57661 tactgaaacc atcgccatga ttgaggagca aaacttcgat attagaacca ttaccatggg
    57721 gatttctctt ttggactgta tcgatccaga tatcaatcgt gctgcggaga aaatctatca
    57781 aaaaattacg acaaaggcgg ctaatttagt agctgttggt gatgaaattg cggctgagtt
    57841 gggaattcct atcgttaata agcgtgtatc ggtgacacct atttctctga ttggggcagc
    57901 gacagatgcg acggactacg tggttctggc aaaagcgctt gataaggctg cgaaagagat
    57961 tggtgtggac tttattggtg gtttttctgc cttagtacaa aaaggttatc aaaagggaga
    58021 tgagattctc atcaattcca ttcctcgcgc tttgactgag acggataagg tctgctcgtc
    58081 agtcaatatc ggctcaacca agtctggtat taatatgacg gctgtggcag atatgggacg
    58141 aattatcaag gaaacggcaa atctttcaga tatgggagcg gctaagttgg ttgtattcgc
    58201 taatgctgtt gaggacaatc catttatggc gggtgccttt catggtgttg gggaagcaga
    58261 tgttatcatc aatgtcggag tttctggtcc tggtgtggtg aaacgtgctt tggaaaaagt
    58321 tcgtggacag agctttgatg tagtagccga aacagttaag aaaactgcct ttaaaatcac
    58381 tcgtatcggt caattggttg gtcaaatggc cagtgagaga ctgggtgtgg agtttggtat
    58441 tgtggacttg agtttggcac caacccctgc gattggagac tctgtggcac gtgtccttga
    58501 ggaaatgggg ctagaaacag ttggcacgca tggaacgacg gttgccttgg ccctcttgaa
    58561 cgaccaagtt aaaaagggtg gagtgatggc ctgcaaccaa gtcggtggtt tatctggcgc
    58621 ctttatccct gtttctgagg atgaaggaat gattgctgca gtgcaaaatg gctctcttaa
    58681 tttagaaaaa ctagaagcta tgacggctat ctgttctgtt ggattggata tgattgccat
    58741 cccagaagat acgcctgctg aaaccattgc ggctatgatt gcggatgaag cagcaatcgg
    58801 tgttatcaac atgaaaacaa cagctgttcg tatcattccc aaaggaagag aaggcgatat
    58861 gattgagttt ggtggtctat taggaactgc acctgttatg aaggttaatg gggcttcgtc
    58921 tgtcgacttc atctctcgcg gtggacaaat cccagcacca attcatagtt ttaaaaatta
    58981 agaaaatagg agaaatttta agttctattt aagattagat gtgtatacta taatcattaa
    59041 ataaagacct cctaatatta tttgaaacag ataacactga attagtttga atttgatttt
    59101 catctaatat ctttatttaa tgaactccta aactttttca taataatctc cttcaaaagt
    59161 cgcctgtatg ggtggctttt attttatcat tcatgatata atagaagcaa acggaggacg
    59221 gaaaatggta aaagtacgat tgtatttggt acgtcatggc aagaccatgt ttaacacgat
    59281 tggtcgcgcg caaggttgga gcgatactcc cttaactgct gaaggtgaac gagggattca
    59341 agagttagga atcggtttgc gagaatctga tctacagttt gagcgcgctt attcgagtga
    59401 ttctggtcgt accattcaga ccatgggaat tatccttgaa gaacttggct tgcaggggaa
    59461 aatcccttat cgcatggaca agcgtatcag agaatggtgt ttcggtagtt ttgatggagc
    59521 ctatgatggc gatcttttca tgggcattat tcctcgtatc tttaatgtgg accacgttca
    59581 ccaattgtct tatgctgaac tggctgaggg cttggtagag gtcgatacag ctggttgggc
    59641 tgaaggctgg gaaaaactca gtggccgaat caaggaaggc tttgaaatga ttgcaaaaga
    59701 aatggaagat caaggtggag gtaacgccct tgttgtcagc catggaatga ctattggaac
    59761 cattgtttat ctgattaatg gcatgcatcc gcatggtcta gataatggta gcgtgacgat
    59821 tcttgaatat gaggacggtc agtttagggt tgaagttgtc ggtgaccgta gttaccgaga
    59881 gctaggatgt gagaagatgg aagaaggctc tatttaatca gtctagactt gcttgccatg
    59941 agctagggat ttgataagaa tatcaagata agaaaaaaca gccgagggca ctcctttcgg
    60001 ctgtttttga tgtggaaaac taaagtgtaa tgctattgct tttagagatt ttcataaaca
    60061 agagcaagga acctactgtt agaacagtca ggatagttga caaggctgcg gctacaccgt
    60121 aatttcctct gagaacctct gtataaatag ctacagtcat tgttcttgtt ttgacattgt
    60181 agaggaggat agaagtagag agttttgaaa tcattgtgac ccaagataag atggctccag
    60241 aaatgatacc agatagcatc attggagttg taatcttagc aaaggtattg agacgactac
    60301 ttcctaagct ttcagcagct tcttcaatac ttggtgctat ttgttgtaag ctagcaacag
    60361 atgagcgaat agtataaggt aatcttctga cagatagaga cataatcaag atgaaagcag
    60421 tccctgtaat cataagaaat ccacttccaa atagaccagt attgaaggaa gaaatgaagg
    60481 caatccctag aacggttcct ggtacaatat aaggtaccat actgaggctg tcaattaagt
    60541 ttgtaaacaa attccgtttt ctaacggcta ggtaggagat aaatgtcgca aatagaacaa
    60601 ctagaactaa ggcaatcaaa gggatacgaa tggtattgaa aatagcagat cccatacgat
    60661 tgaaagctac cttgtaactg tttggagaat aacctttaac agataccata cctgatgttt
    60721 ttaggaaaga ggtataaatt aagtagattt gaggtaaaac agagataaag ataattccgt
    60781 agactgttgc ataaatggca gctatttttc cttttgtagt ttttttaggc tcaattggat
    60841 ggagcagatt catgctgaaa ctgtagcggt ttgcaatgtg tttttggata aggaaaattg
    60901 ccaaggcaat gataatcgcc ataattgcaa aagcagaatt tcctccaacc tcgctaataa
    60961 attgggtata aatcaggaca gggaaagtcc gatatccttc gtcaatcaac ataggcgttc
    61021 caaagtctga gaatgctctc ataaatacaa gcaaggagct gctagtaagg ttggaactag
    61081 gagaggtaaa acaaccgtta cgatacgctt aaatccgaag gaccccatgc tttcagctgc
    61141 ttcaagtaga gaattgtcaa tactgttcat tgttccagca acatatagaa ataccagtgg
    61201 gaatagttgc agtgtaaaga caagtacaat tcctttgaat ccataaatat cgatagctgg
    61261 aagatgaagg gcatttgtca aaaatttagt gatgacctca tttcgtccca gcaagagaat
    61321 tcaggagtag gctcctacga aaggagctga catggaagca atgataatca atatttgtag
    61381 aaatttcttc cccttgaagt catacataga gaagagataa gctaataggg ttcctacaac
    61441 taaggaagtg atagtagcgg taatggaaac cttgaaactg ttgactagtg tctcagagta
    61501 gtaggcttta ctaaagaaag tgacaaaatt agctagtgag aattgtcctt catgtataag
    61561 tgcttgcttg agcacggtaa cgataggata aacgagaaag acaagatagg taagaaagat
    61621 gaagaaagag gaagctgtcc aaatatttag ttttttacat tccatggttg actcctttta
    61681 tcaggttttg ggaaccatct gcagaaaaga tgtttaattt ttgcgtattg attcgtagac
    61741 gaatacgatt gcctttttgt agttcttctt caaaagttga ttcttcacta acttaaattt
    61801 ttgaggcaaa acctgtctca atgaaatact ccgtatttag tccaagatag acgctatcgc
    61861 taatagttcc ttcgatatct ccagattcat ctttgataaa ctcttcggga cgaatgctta
    61921 catgaatagc ttgctcctca acctgatcaa gagctggcat tcgaagggca tagccatctg
    61981 aaaagacgat ataagcgccg tcgctccgtt tttcaagatt ggcagggata atatttgtgc
    62041 gtccgataaa ggttgccaca aactcattag ctggtttatg atagagttat tttggtcggc
    62101 cgatttgttg gatcacccca tctttcataa cagcaatttg gtctgaaata gccatggctt
    62161 cttcttggtc gtgggttaca taaacagttg taattcccac ttcgtgttgg atttctcgga
    62221 tggcttgacg catatccaag cgaagtttgg cctccagatt actaagtggc tcgtccatga
    62281 ggagaacact tggattaacc gctaaggcgc atgccaaggt gacacgttgt tgttgtccac
    62341 cactgagttt atcgggcttt cgatccgcat attgagcaat ttgcatgagt tcaagatact
    62401 tgttggtctg ttgaatcaat tcttcttttg gaaccttctt ttgcataaga ccaaaagcaa
    62461 cgttgtctcg gacagtcaaa tgtgggaaaa tagcgtagtt ttggaaaacc atcccgatat
    62521 tgcgtttgct gggttccata ttattgattt ttgtatcatc gaagtaaaat tctccacctt
    62581 cgatactgtt gaaacctgca atcatacgaa gaagggtcgt tttcccacat cctgaagctc
    62641 caagaagggt aaagagactt ccttttggaa ttgtaatgtt caaattctca ataacaggga
    62701 catcgtggta gatttttttg gcgttaataa tttcgatctc actcatagtg aacctctttt
    62761 actgtttaga ttggatatct gtaaagactt cgttgtattt cttaacgata tctgatttat
    62821 tcttgatgac ataatcataa tcttcagtga gtgttttgat tttgtcaatt ggtttcatgt
    62881 tttcgcttgt tttagcattt ttacgaacag gacggttagt agtggttgta ccaagtgtat
    62941 cttgtacttc ttgagagata ataaaatcga taaatttctt ggcattttcc atatttttag
    63001 attttttaac gatagcagca ctagcaggta ggaagacggt tccttctttt ggatagacta
    63061 ccttaatgtt agctccgtca tttaagagtt taactgctgg atcttcataa gagagactaa
    63121 cagtcatttc tccatcagcg actgctttat agacaccaga tgaacttaaa ccgattttat
    63181 agtatattga aactagaata gtacacatct acttctaaaa cattgttaga aatcgatttg
    63241 actgtcctga ttaatttgtc ctgttcttat ttcattttac tataccatca ataagtgtga
    63301 aaagatcttt tacataagac caagccttat catctttgta accaccttga gcttgtagca
    63361 tatttgttaa ttgagcaaag gcgctagaag agtttgctgg gtcagcagtt gcgatttttc
    63421 cttttagttc aggtttgaga aggtcgctat atccttcgat gttcatgcct ttagttaaat
    63481 cagggtggac gattaaaaca ctaccatcta gtgtataagg agtagagaag ccagttgtgt
    63541 tttgatattc tttgataaca ttatcatttt cttttgaaat atagttttca aagagttctc
    63601 cgtgggtagc atattgtgta taagaaccac caaagataat atcagctaca ggaacttctt
    63661 tttctgactc tagttttttg aaaagttctc cagtaccagc ttgaatcagt tctattttga
    63721 taccatattt ttcttcaaag gcaggaatag ttgctccaat taagccttct gagtttggtg
    63781 aataaacgac tagcgaacca ccgtctcctt tatcagatga actgtcatcg gcagattcat
    63841 tagaagaaca agcagcataa tacatccatt tctttttcat gatggatacc tccgttgtgt
    63901 tatttaagtt tattttaaaa caatgtaagc gtttttaaaa cctacaattc tattctatag
    63961 tgtattgaat ctataacagt acacattgac tgctaaaata tttctataaa ttaatttgac
    64021 tttcctgata gagatgttca catcttattt caattcacta tattagagta aaattctcta
    64081 caaaaaaaag aatagcctat tttactattt ttccgagtga tttcaattcc tttggggaaa
    64141 tatggagata ctttttaaat cctgacaaat ggttgtttct ttttctaaat cggtgatact
    64201 gtatcggaga atgcgcgtga ggtcacaaag gctgcgatag agcttctatg gagaatttct
    64261 ttttggagag attttttaaa ggaatgagac atccgctacc tccttggaag gtttttttgt
    64321 gataagtata gcagtttaaa aattctagag caaggtaaaa tagaaaaggt ttggctaaaa
    64381 ttttttagct aaaccttttg aaaagttaag tatgtattat agatgcttgt tatctgcaaa
    64441 tagctagagc atttcaagga aataaactag aaataacaat taatatggtg gttcagaaat
    64501 accttttgat aatcaataag atcttcagga tgaagtgcgt tgattccatc catttcatat
    64561 ttccgattta ataaacgata tttgttttca ccaaattgat gaaaagggag tagttgaact
    64621 tggtcgatat ttaatgagtt aaatagagta gcgaattttt ctgcatcctc taaactattg
    64681 ttaaaattag gaataactgg gattcttaaa acgatagttt tattttgtga aaaagcataa
    64741 tgaatgtttt taataatcat ttgattaaaa accccagtca cttttttatg tttta
//
LOCUS       DBJKQU010000007        63731 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.007, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000007 DBJKQU010000000
VERSION     DBJKQU010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 63731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63731
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.007"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(<1..916)
                     /gene="pavB"
                     /locus_tag="ACSUUC_000503"
     CDS             complement(<1..916)
                     /gene="pavB"
                     /locus_tag="ACSUUC_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HHQ8053785.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAV"
     gene            complement(1032..1442)
                     /locus_tag="ACSUUC_000504"
     CDS             complement(1032..1442)
                     /locus_tag="ACSUUC_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HHQ8053786.1"
                     /translation="MYYLPVDFYRYLIGREGQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            complement(1509..1610)
                     /locus_tag="ACSUUC_000505"
                     /pseudo
     CDS             complement(1509..1610)
                     /locus_tag="ACSUUC_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
     gene            complement(2037..2702)
                     /locus_tag="ACSUUC_000506"
     CDS             complement(2037..2702)
                     /locus_tag="ACSUUC_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HHQ8053787.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(2716..4095)
                     /locus_tag="ACSUUC_000507"
     CDS             complement(2716..4095)
                     /locus_tag="ACSUUC_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HHQ8053788.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            complement(4708..5472)
                     /locus_tag="ACSUUC_000508"
     CDS             complement(4708..5472)
                     /locus_tag="ACSUUC_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HHQ8053789.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(5689..6246)
                     /locus_tag="ACSUUC_000509"
     CDS             complement(5689..6246)
                     /locus_tag="ACSUUC_000509"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HHQ8053790.1"
                     /translation="MTSEYQKMIAGEFYRPSDPELRALAQASRQKQAAFNKEENPLKG
                     AEIIKTWFASTGKNLYINTRLMVDYGVNIHLGENFYSNWNLTMLDICPIRIGDNAMIG
                     PNCQFLTPLHPLDPQERNSGIEYGKPITIGDNFWTGGGVIVLPGVTLGNNVVAGAGAV
                     ITKSFGDNVVLAGNPARVIKEIPVK"
     gene            complement(6352..7206)
                     /locus_tag="ACSUUC_000510"
     CDS             complement(6352..7206)
                     /locus_tag="ACSUUC_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHQ8053791.1"
                     /translation="MTYEYQSHIYLAEAVLNVKDLVSQTVFYQQIIGLEILSQTDTEV
                     VLGLGGKALVHLIQAQEGGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEALYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEVLAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSRQFYQTVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLDPRKQVLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            complement(7562..13132)
                     /gene="zmpC"
                     /locus_tag="ACSUUC_000511"
     CDS             complement(7562..13132)
                     /gene="zmpC"
                     /locus_tag="ACSUUC_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease ZmpC"
                     /protein_id="HHQ8053792.1"
                     /translation="MSRKSIGEKRHSFSMRKLSVGLVSVTVSSFFLMSQGIQSVSADN
                     MESPIHYKYMTEGKLTDEEKSLLVEALPQLAEESDDTYYLVYRSQQFLPNTGFNPTVG
                     TFLFTAGLSLLVLLVSKRENGKKRLVHFLLLTSMGVQLLPASAFGLTSQILSAYNSQL
                     SIGVGEHLPEPLKIEGYQYIGYIKTKKQDNTELSRTVDGKYSAQRDSQPNSTKTSDVV
                     HSADLEWNQGQGKVSLQGEASGDDGLSEKSSIAADNLSSNDSFASQVEQNPDHKGESV
                     VRPTVPEQGNPVSATTVQSAEEEVLATTNDRPEYKLPLETKGTQEPGHEGEAAVREDL
                     PVYTKPLETKGTQGPGHEGEAAVREEEPAYTEPLATKGTQEPGHEGKATVREETLEYT
                     EPVATKGTQEPEHEGEAAVEEELPALEVTTRNRTEIQNIPYTTEEIQDPTLLKNRRKI
                     ERQGQAGTRTIQYEDYIVNGNVVETKEVSRTEVAPVNEVVKVGTLVKVKPTVEITNLT
                     KVENKKSITVSYNLIDTTSAYVSAKTQVFHGDKLVKEVDIENPAKEQVISGLDYYTPY
                     TVKTHLTYNLGENNEENTETSTQDFQLEYKKIEIKDIDSVELYGKENDRYRRYLSLSE
                     APTDTAKYFVKVKSDRFKEMYLPVKSITENTDGTYKVTVAVDQLVEEGTDGYKDDYTF
                     TVAKSKAEQPGVYTSFKQLVTAMQSNLSGVYTLASDMTADEVSLGDKQTSYLTGAFTG
                     SLIGSDGTKSYAIYDLKKPLFDTLNGATVRDLDIKTVSADSKENVAALAKAANSANIN
                     NVAVEGKISGAKSVAGLVASATNTVIENSSFTGKLIANHQDSNKNDTGGIVGNITGNS
                     SRVNKVRVDALISTNARNNNQTAGGIVGRLENGALISNSVATGEIRNGQGYSRVGGIV
                     GSTWQNGRVNNVVSNVDVGDGYVITGDQYAAADVKNASTSVDNRKADRFATKLSKDQI
                     DAKVADYGITVTLDDTGQDLKRNLREVDYTRLNKAEAERKVAYSNIEKLMPFYNKDLV
                     VHYGNKVATTDKLYTTELLDVVPMKDDEVVTDINNKKNSINKVMLHFKDNTVEYLDVT
                     FKENFINSQVIEYNVTGKEYIFTPEAFVSDYTAITNNVLSDLQNVTLNSEATKKVLGA
                     ANDAALDNLYLDRQFEEVKANIAEHLRKVLAMDKSINTTGDGVVEYVSEKIKNNKEAF
                     MLGLTYMNRWYDINYGKMNTKDLSTYKFDFNGNNETSTLDTIVALGNSGLDNLRASNT
                     VGLYANKLASVKGEDSVFDFVEAYRKLFLPNKTNNEWFKENTKAYIVEMKSDIAEVRE
                     KQESPTADRKYSLGVYDRISAPSWGHKSMLLPLLTLPEESVYISSNMSTLAFGSYERY
                     RDSVDGVILSGDALRTYVRNRVDIAAKRHRDHYDIWYNLLDSASKEKLFRSVIVYDGF
                     NVKDETGRTYWARLTDKNIGSIKEFFGPVGKWYEYNSSAGAYANGSLTHFVLDRLLDA
                     YGTSVYTHEMVHNSDSAIYFEGNGRREGLGAELYALGLLQSVDSVNSHILALNTLYKA
                     EKDDLNRLHTYNPVERFDSDEALQSYMHGSYDVMYTLDAMEAKAILAQNNDVKKKWFR
                     KIENYYVRDTRHNKDTHAGNKVRPLTDEEVANLTSLNSLIDNDIINRRSYDDNREYKR
                     NGYYTISMFSPVYAALSNSKGAPGDIMFRKIAYELLAEKGYHKGFLPYVSNQYGAEAF
                     ASGSKTFSSWHGRDVALVTDDLVFKKVFNGEYSSWADFKKAMFKQRIDKQDNLKPITI
                     QYELGNPNSTKEVTITTAAQMQQLINEAAAKDITNIDRATSHTPASWVHLLKQKIYNA
                     YLRTTDDFRNSIYK"
     gene            complement(13584..14797)
                     /locus_tag="ACSUUC_000512"
                     /pseudo
     CDS             complement(13584..14797)
                     /locus_tag="ACSUUC_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041867.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
     gene            complement(14914..15951)
                     /locus_tag="ACSUUC_000513"
     CDS             complement(14914..15951)
                     /locus_tag="ACSUUC_000513"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HHQ8053793.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            complement(16067..17233)
                     /locus_tag="ACSUUC_000514"
     CDS             complement(16067..17233)
                     /locus_tag="ACSUUC_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HHQ8053794.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESLATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            complement(17532..17936)
                     /locus_tag="ACSUUC_000515"
     CDS             complement(17532..17936)
                     /locus_tag="ACSUUC_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHQ8053795.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            complement(17943..18758)
                     /locus_tag="ACSUUC_000516"
     CDS             complement(17943..18758)
                     /locus_tag="ACSUUC_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHQ8053796.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            complement(18745..19650)
                     /locus_tag="ACSUUC_000517"
     CDS             complement(18745..19650)
                     /locus_tag="ACSUUC_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HHQ8053797.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            complement(19678..20154)
                     /locus_tag="ACSUUC_000518"
     CDS             complement(19678..20154)
                     /locus_tag="ACSUUC_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHQ8053798.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            complement(20151..21938)
                     /locus_tag="ACSUUC_000519"
     CDS             complement(20151..21938)
                     /locus_tag="ACSUUC_000519"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004565 - beta-galactosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 35 protein"
                     /protein_id="HHQ8053799.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            22286..23002
                     /locus_tag="ACSUUC_000520"
     CDS             22286..23002
                     /locus_tag="ACSUUC_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHQ8053800.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            23317..27255
                     /gene="strH"
                     /locus_tag="ACSUUC_000521"
     CDS             23317..27255
                     /gene="strH"
                     /locus_tag="ACSUUC_000521"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HHQ8053801.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(27310..28608)
                     /gene="purB"
                     /locus_tag="ACSUUC_000522"
     CDS             complement(27310..28608)
                     /gene="purB"
                     /locus_tag="ACSUUC_000522"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HHQ8053802.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(28671..28898)
                     /locus_tag="ACSUUC_000523"
     CDS             complement(28671..28898)
                     /locus_tag="ACSUUC_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HHQ8053803.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVKAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            complement(28908..29999)
                     /gene="purK"
                     /locus_tag="ACSUUC_000524"
     CDS             complement(28908..29999)
                     /gene="purK"
                     /locus_tag="ACSUUC_000524"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HHQ8053804.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            complement(29986..30474)
                     /gene="purE"
                     /locus_tag="ACSUUC_000525"
     CDS             complement(29986..30474)
                     /gene="purE"
                     /locus_tag="ACSUUC_000525"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HHQ8053805.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            complement(30504..30620)
                     /locus_tag="ACSUUC_000526"
     CDS             complement(30504..30620)
                     /locus_tag="ACSUUC_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HHQ8053806.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            complement(30877..32139)
                     /gene="purD"
                     /locus_tag="ACSUUC_000527"
     CDS             complement(30877..32139)
                     /gene="purD"
                     /locus_tag="ACSUUC_000527"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HHQ8053807.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            complement(32261..33808)
                     /gene="purH"
                     /locus_tag="ACSUUC_000528"
     CDS             complement(32261..33808)
                     /gene="purH"
                     /locus_tag="ACSUUC_000528"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HHQ8053808.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDMTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELSAN
                     GETTYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHM
                     NPCGIGQADNIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            complement(33833..34342)
                     /locus_tag="ACSUUC_000529"
     CDS             complement(33833..34342)
                     /locus_tag="ACSUUC_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HHQ8053809.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            complement(34426..34971)
                     /gene="purN"
                     /locus_tag="ACSUUC_000530"
     CDS             complement(34426..34971)
                     /gene="purN"
                     /locus_tag="ACSUUC_000530"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HHQ8053810.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            complement(34968..35990)
                     /gene="purM"
                     /locus_tag="ACSUUC_000531"
     CDS             complement(34968..35990)
                     /gene="purM"
                     /locus_tag="ACSUUC_000531"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HHQ8053811.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLVSSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            complement(36027..37469)
                     /gene="purF"
                     /locus_tag="ACSUUC_000532"
     CDS             complement(36027..37469)
                     /gene="purF"
                     /locus_tag="ACSUUC_000532"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HHQ8053812.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGKLKRHRDMGLLSEVFRNPANLDKLTGTGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEDRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSMTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            complement(37562..41287)
                     /locus_tag="ACSUUC_000533"
     CDS             complement(37562..41287)
                     /locus_tag="ACSUUC_000533"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HHQ8053813.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNVGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVAIVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELETALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEVANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            complement(41344..42051)
                     /gene="purC"
                     /locus_tag="ACSUUC_000534"
     CDS             complement(41344..42051)
                     /gene="purC"
                     /locus_tag="ACSUUC_000534"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HHQ8053814.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            complement(42221..43570)
                     /gene="comB"
                     /locus_tag="ACSUUC_000535"
     CDS             complement(42221..43570)
                     /gene="comB"
                     /locus_tag="ACSUUC_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HHQ8053815.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKEDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLINQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            complement(43583..45736)
                     /gene="comA"
                     /locus_tag="ACSUUC_000536"
     CDS             complement(43583..45736)
                     /gene="comA"
                     /locus_tag="ACSUUC_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HHQ8053816.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKEQKNGLFSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            complement(46323..46448)
                     /locus_tag="ACSUUC_000537"
     CDS             complement(46323..46448)
                     /locus_tag="ACSUUC_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HHQ8053817.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            complement(46451..46681)
                     /gene="blpU"
                     /locus_tag="ACSUUC_000538"
                     /pseudo
     CDS             complement(46451..46681)
                     /gene="blpU"
                     /locus_tag="ACSUUC_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
     gene            complement(46884..47184)
                     /locus_tag="ACSUUC_000539"
                     /pseudo
     CDS             complement(46884..47184)
                     /locus_tag="ACSUUC_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(47221..47454)
                     /locus_tag="ACSUUC_000540"
     CDS             complement(47221..47454)
                     /locus_tag="ACSUUC_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HHQ8053818.1"
                     /translation="MKEKEIFDSIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            complement(47460..48452)
                     /gene="plsX"
                     /locus_tag="ACSUUC_000541"
     CDS             complement(47460..48452)
                     /gene="plsX"
                     /locus_tag="ACSUUC_000541"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HHQ8053819.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETEVVAQTAREFSGE"
     gene            complement(48449..49219)
                     /gene="recO"
                     /locus_tag="ACSUUC_000542"
     CDS             complement(48449..49219)
                     /gene="recO"
                     /locus_tag="ACSUUC_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HHQ8053820.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(49216..50385)
                     /locus_tag="ACSUUC_000543"
     CDS             complement(49216..50385)
                     /locus_tag="ACSUUC_000543"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHQ8053821.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTSQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            50534..51544
                     /locus_tag="ACSUUC_000544"
     CDS             50534..51544
                     /locus_tag="ACSUUC_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HHQ8053822.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(51727..52164)
                     /locus_tag="ACSUUC_000545"
     CDS             complement(51727..52164)
                     /locus_tag="ACSUUC_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HHQ8053823.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(52249..54882)
                     /gene="polA"
                     /locus_tag="ACSUUC_000546"
     CDS             complement(52249..54882)
                     /gene="polA"
                     /locus_tag="ACSUUC_000546"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HHQ8053824.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            55138..56045
                     /locus_tag="ACSUUC_000547"
                     /pseudo
     CDS             55138..56045
                     /locus_tag="ACSUUC_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            56171..56452
                     /locus_tag="ACSUUC_000548"
                     /pseudo
     CDS             56171..56452
                     /locus_tag="ACSUUC_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(56586..57554)
                     /locus_tag="ACSUUC_000549"
     CDS             complement(56586..57554)
                     /locus_tag="ACSUUC_000549"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HHQ8053825.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(57699..58513)
                     /locus_tag="ACSUUC_000550"
                     /pseudo
     CDS             complement(57699..58513)
                     /locus_tag="ACSUUC_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(58538..59035)
                     /locus_tag="ACSUUC_000551"
     CDS             complement(58538..59035)
                     /locus_tag="ACSUUC_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HHQ8053826.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(59108..60469)
                     /gene="radA"
                     /locus_tag="ACSUUC_000552"
     CDS             complement(59108..60469)
                     /gene="radA"
                     /locus_tag="ACSUUC_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HHQ8053827.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLQQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(60483..60998)
                     /locus_tag="ACSUUC_000553"
     CDS             complement(60483..60998)
                     /locus_tag="ACSUUC_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HHQ8053828.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(61000..61443)
                     /locus_tag="ACSUUC_000554"
     CDS             complement(61000..61443)
                     /locus_tag="ACSUUC_000554"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HHQ8053829.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            complement(61503..61596)
                     /gene="ffs"
                     /locus_tag="ACSUUC_000555"
     ncRNA           complement(61503..61596)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACSUUC_000555"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(61629..62096)
                     /gene="tadA"
                     /locus_tag="ACSUUC_000556"
     CDS             complement(61629..62096)
                     /gene="tadA"
                     /locus_tag="ACSUUC_000556"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HHQ8053830.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(62297..63583)
                     /locus_tag="ACSUUC_000557"
     CDS             complement(62297..63583)
                     /locus_tag="ACSUUC_000557"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HHQ8053831.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
BASE COUNT        18673 a        15000 c        11787 g        18271 t
ORIGIN      
        1 taacagcttt ttcgacagtt tctttagcaa ctaatccatt gatgttgatg tctacatttt
       61 tagtagcaac tagattagtc aagtcagctt taccgtcttt atttccgtaa actttaacag
      121 tagctttata agtttgagta ccattagcgc gaagttgatc aattaaagct tgaccttgtt
      181 taccaacagt attgccattt aagtctactt catagaagta tttccctttt gttaatcctt
      241 caagaggagg taaagcagga tttttagcag taccattgtc agaccaagga gcattatccg
      301 aagcttttag taatagacga gttaacatac catcaccagc gaatagttca taagggatta
      361 cttggtttac accggcagtg aaaggacctt tcccttcagc tttttcaaga taagcagcag
      421 gaacatcgat gctgtctttt gtattttctt tcactccacc ttttacttgt tcaggagtag
      481 tttctgctgg acttgcttgt gtcccatcca catcagctgt atctacagtt tcttttaaga
      541 catctgttag ctctggattt ttttgagctt cttcatcttt ttcaaaaagt gtatccagac
      601 tagaagagtt tgtttcctcg ctcacttcag ttctttctgt aggtgtcgga agtgaattcg
      661 tatttccagt aacgccctca ggtttcgctt gagtgagaac ggtgtctcct ggtttttctg
      721 ataagtcacc ctctttcgtt cccgatgtct cttcaggtaa gacttgacct ggggtcggat
      781 tgaccacatc ggcacgtaca gaacttggct gaccaactag gacaaagaag ccactagcca
      841 caacaactga ggcaacaccg acactgagac ggcgaataga ccaacgagta tatctttgat
      901 ttggattgaa tttcatagga ttctccttag agtctttctt tatttgatga ctctagtata
      961 atctcctgaa attaaaaagg actaagaaaa agttaaaatt tttcttaaat ccctcttata
     1021 aaacacttat attaattaaa tccataaaca gatttggtga tttgatagac gacattggac
     1081 agtttgcgat ctggcaagac agaatgtttg gtcaaacggc tcaacatggt cttacgaata
     1141 gcctgaaaga cttctggatt tttctgctga atataggtcc acaattggcg tttttttgcc
     1201 agatgctccg ctgtttcaga tcggttgagc agggtactgg aaatcaccgt cgtgatttca
     1261 atatgattca gcagatattc tcgcattttg ggatgactca cttgggacaa atcaagctgg
     1321 tctaccaaga gtcgattgac cttgagttgc tggtcaatgc acttaatcat cacttgctca
     1381 ttgacagact ggccctcacg cccaatcaaa taacgataga aatcgacagg cagatagtac
     1441 atggtcttga cctgctgaag gggcgtaaag acaaagagat tatcgacata aaaagtatgt
     1501 tcaggcaatt agaactggct agcacgcaac aaatctgtcc gataaatcag cgagtgcatc
     1561 atgatatact ggcctttgga gaaatttccg acctggtccc agccaatcac tagcgactcc
     1621 acacagtaat gaagataggc tgctgcatta tagctagaaa tggcgataga caataacttc
     1681 ataatctgct cctttagggg actgattttt tcttatactc ttcgaaaatc tcttcaaacc
     1741 gcgtcaacat cgccttgccg tatagatgtt actgacttcg tcagttctat ctgcaacctc
     1801 aaaacagtgt tttgagctga cttcgtcagt tctatccaca acctcaaaac agtgttttaa
     1861 gcagcccgta gctagtttcc tagtttgatc tttgattttc attgagtatt actctctctt
     1921 gtcacttcct tctattttac cataaagtcc agcctttgaa gaacttttac tagaagacaa
     1981 ggggcttctg tctctatttg ccatcttggg catcaaaaaa gaggggtcat ccctctttac
     2041 gaattcaatg ctactagggt atccaaatac tggttgttga tgactgccaa aatataggta
     2101 tctgctttca agaggtcatc tggtccaaat tcaacatcca atggggaatt ttcctgctct
     2161 cggaaaccca aaatattcag attgtatttg ccacggaggt ctaatttact cagactttga
     2221 cctgcccaag actgaggaat tttcatctcc acgatagaca catttttatc caactgaaag
     2281 acatcaacac tattatggaa aagaatggtc tgtgctagag actgccccat ttcatactct
     2341 ggcgagataa ccgagtcagc tccaatcttt tctagcactt tcttagcggt ctgacttttg
     2401 accttagcaa taacagtcgg tacccccaaa ctcttacagt gcataaccgc aagcacactc
     2461 gactccagat tttcacctgt cgcgactaca acggtatcgc aggtatcaat ccctgctgat
     2521 ctcaataatt cttcatctgt gatgtcacca atcactccac gcgccaaaac tggctcaaac
     2581 tgattgatgc gctctgcgtg gtcatcaata gcgataatat tcatatcctg cttggctagg
     2641 gcagctagga cactgctccc aaaaattccc aagcccaaaa ttccaatcgt acgatctgac
     2701 atgctctttc ctttcttaac caatactaat atctgctttc atatagtgaa tcatatcttt
     2761 cttttctgga tggtaatctg ccaagctaac aaacaaggtc aagggaccaa ttcgtcccat
     2821 aaacataagt ggcatgataa cactgagagc caatttccca aggtcaggag tcagatttgc
     2881 cgttacacca actgtactaa gagctgaaat ggtttcaaat atgaggtgga taaagggagg
     2941 attgcctttg gctgttatcc ctagcagaat caatcctatt aagaagctca tcaaaaagat
     3001 aataaagaca ctaaaggatt tttgaaccgt tcgcggcgca atcgttcgtc tcgcaacatt
     3061 ggcatgaggc aagcctagaa gctcacttcg tgcaaagacc aagaggacaa aaaatgtcgt
     3121 aatcttgagt cccccagctg ttcctccagg tgccccacct agaaacatct gtaagatata
     3181 aatcaaaaga gtcacaggat gagcctgagt ataatctatc gtagaaaagc cagctgttcg
     3241 catcgtcact gtttgaaaaa agctaactaa aaccttatcg gcaacaggga gattgccaat
     3301 cgttccagca ttgttccact caagaaagag agtagttgcc gttccaaata acaacaaacc
     3361 tatagtcaac aatagtacaa gcttcgtatg aaagtgcaga cgtccttttt tctttcttcc
     3421 tacatgacca gccaaatcaa accagaccat aaaaccaagg ccgcctgtaa taattaagcc
     3481 tgcaatcacc agattgacca gtaaatcggt ctgaaaagca aataaactgg tgctccctaa
     3541 attatcaaaa ccggcattac agaaggctga gatcgctaga aaaatggaac taaaaagacc
     3601 acgtccccag ccaagttgag gaataaggcg aaaactaagc aaaatagctc ccaagctctc
     3661 aaccaaaaag gtcgtgagaa aaatagaata gacaaacttt ctcaaagatc gagtttctcc
     3721 ataactaaaa ctatcctgaa tagttgcacg gctacgaaga ctaagctttt gcttgctctg
     3781 gatatagaaa accccaataa aggtcatgag ccctagacca ccgatctgaa tcaagagcaa
     3841 acagattatt tgaccccaga tattataggt gtgagctact ggaagggttg agagacccgt
     3901 cacacagact gcagatacag cagtgaaaag atgatcaaaa taagtcgctc gtgagctttc
     3961 aacttggaca aagggcaagc tcaaaagaag agagcctagt aaaatgacca aggcaaaact
     4021 caaaaaaata cgacgggctg gcgataaacg agataagcct agctctattt tttccttaga
     4081 taatttgaat aacatgtttc cattgtacca taaaaagttc gaaatgactt agataggata
     4141 aggcaaaatc tactaacacc aaacctaaaa aatgccacct ttttattgat agcttaggca
     4201 agaacaatac ttgatagatg tgactatagg tcaaaaaagc aagacaggag cttttaacgc
     4261 cagctactct atatgctttt caggagaaaa tttctctttt tgattatagg caatgaaaac
     4321 caaggcatcg attagaaagc tagtcacagg ttgctcaaaa cactgttttg aggttgcaaa
     4381 tagaactgac gaagtcagct caaaacaccg ttttgaggtt gccggataag actgacgaag
     4441 tcagtaacat atacctacgg caaggtgaag ctgacctggt ttgaagagat tttcgaagag
     4501 tatcatttca tctcactcta aatcttatcg acataaaacg catagtgtca aagttttcat
     4561 cacctgatat gatacgtttt tctgatttta aagatttttc ccaacctcaa catgcctagg
     4621 acaagaggaa ggtgacctcg tttaaacata tttttgaaaa gtatgagcta gacattttat
     4681 gataaaacaa atcctttgcc agtacaacta aaggtggtga acacttgcta aactcagttc
     4741 tagcgcctta ttaaaagctt ccgagcccca gtcacgactg tcgtactggt ccaagtccgc
     4801 tagagaatct gctgtgaaca acaattcacc ccagagaacc ccacgcaatt gagctactgc
     4861 cgcaagagcg gaacactcca tctccacaac agcacagtct tcttccttgc gataagccac
     4921 cttttcagcc gtttctcggt aaaaaccatc tgtggaccag gtcatgactt cttcataagg
     4981 aatccctcta tcatccaaaa ctcgctcaat ggcagcaata gcctctggct gcatttccat
     5041 ataacgagaa ggtgccacat agtggtaact ggctccttca tctcgcagag cgcgaacagg
     5101 gactagaaag gcattttcct ctatatcagc taggacacca caggtcccag tagagataat
     5161 ctgctccaca ccatagccaa tcaaccaatc cataaactgg gctgctggag ctgaaccgac
     5221 aggagcctga accagacaaa tctcctcgtc cttgtagttc acgacataaa ctggataggt
     5281 cttggtggca gaaacaaatt cgccaacaca gttcgcccct acttccctcg catagcggtc
     5341 aatctcctca cctaaaaatg cataaacaca cttctttggc aactgcaagt ccagcccctc
     5401 gtgattgggc atgataaccg cctgaggatt gtcatcaaac tctaaaatag gaatcgcatg
     5461 tttctgaatc atagcctgcc tcctctaatt ttgtactatt gtatcaaaat ctgaccgagt
     5521 gtcaaggagg aagctgatga actgaggaga aaaacatccc acttacgaga tgctttgaac
     5581 ttgcttaatg aaacagactt gctaagagat agagtaggta aatgtgaact gggtaaaaaa
     5641 tgatgaaacc tacaaaaaag aaacaacccc agctgttcct ttttacttct atttaacagg
     5701 tatttcctta atcacgcgcg caggattgcc agctaggaca acgttgtcgc caaaagattt
     5761 ggtaattact gcccctgctc ctgcaacgac attatttccc agtgtcactc caggaaggac
     5821 aatgacgcca ccaccagtcc agaaattatc tccgattgtg ataggctttc cgtactcgat
     5881 acctgaattg cgttcctgtg gatctagtgg atggaggggt gtcaaaaact gacaattagg
     5941 accaatcata gcattgtccc cgatacgaat gggacagata tccagcatgg tcaagttcca
     6001 attagaataa aaattttccc ctagatggat gttgacaccg tagtccacca tcaagcgagt
     6061 gttgatgtaa agatttttcc cggttgaggc aaaccaagtc ttgatgattt cggctccctt
     6121 caaggggttc tcttccttgt taaaggcggc ctgtttttgg cgagaagcct gagctaaggc
     6181 tctcagttct gggtctgatg gacggtaaaa ctctcctgct atcattttct ggtattcgct
     6241 agtcatatta ttcttctcct tattccctac tatcatatca aattttccac gtatctgact
     6301 agaataagga gcactttcta caattgatgc tctaccttca tcacatacca tctatctagc
     6361 taaacgaata cgggtcacga tgccatctga gtctgtgatt tccaattgga tcgatgtcat
     6421 ccatttgatt ggtgcgtcaa cttcttgtgc tcgttgggca atcgttaaca gttcttcttt
     6481 atgtgcgact tcgatgacat agtaggctaa acctggtagg acttgtttac gcggatccag
     6541 accttttcct ccccattcgt tgactgctaa atgatgatgg tagtccccag ctgcgatcca
     6601 actagcacta ggcacactga atttatcctc gagccctaac accgtttgat aaaactgtct
     6661 ggactttcga ctatccttga cagaaagatg aatatgcccc attctcgtac cctctgctag
     6721 gataaaaggc tctactcttt cccccaactc atagatatcc tgagccgcaa ggacttcagt
     6781 caccccgata atacgtccat cttctcgaat atcccatgtg gaaactggct tatctcgata
     6841 gagttcaatg ccatttccct ccaagtcctc taagtaaagg gcctcactgt aaccgtgatc
     6901 tgcaccgcca acaagaggaa tctgtaaatc cgtcaggtgc ttcaagacat ccgccaaagc
     6961 ctttcgtgtc ggcaaaagaa tagccagatg gtaaagacca taatgttccc ttacttctcc
     7021 accctcttgt gcttgaatca agtgtaccaa ggcttttcct ccaagtccca gaacgacctc
     7081 tgtatccgtt tgagatagga tttctaaacc aataatctgc tgataaaaaa ctgtttgact
     7141 gaccaaatcc ttcacattta aaactgcctc tgctaaataa atgtggctct ggtattcata
     7201 tgtcataaat atttcctctt ttattgtaac tttaattatt acaactatta tataacttcc
     7261 ctcaagaaag tcaagccaga caacttgaag catcccactc agcaaaaaac aatcccagaa
     7321 aaaatcttct aggattgttt tgtatttatt ttactagact agcaaagtta tttctcaaat
     7381 caacattttc tgtgggattg aaatccacct tgtcaccatt ggtcgttgat gagttgaaga
     7441 tgattcctgc aatctgcatt caatcaaatc tctacatcga tccataagaa aaaggagtcg
     7501 atttgtcatc tgactcctca tccttacaag aaacactact caacaatgaa actctacaat
     7561 cttatttata tatagaattt ctaaagtcat ctgtagtgcg aagatatgca ttatagattt
     7621 tttgttttaa taaatgcacc caacttgctg gggtatgact cgttgcacga tctatattag
     7681 taatatcttt cgcagccgct tcattaatta attgttgcat ttgtgcagcc gttgttatag
     7741 ttacttcttt tgtactatta ggattaccta attcgtattg aattgttatt ggtttcagat
     7801 tatcttgttt atctatacgt tgtttaaaca ttgctttttt gaaatcagcc catgatgagt
     7861 actcaccatt gaatactttc ttaaatacta aatcatctgt cactaaagca acatctcttc
     7921 catgccatga tgagaatgtt ttgcttccgc tggcaaatgc ttctgctccg tactgattag
     7981 aaacataagg taggaatcct ttgtgataac ctttttccgc aagtaattca taagctattt
     8041 ttctaaacat aatatctcca ggagcacctt tcgaattgct tagcgctgcg tatacaggag
     8101 agaacatact tatagtatag tagccatttc gtttatattc tctattatca tcatagctac
     8161 gtctatttat gatgtcgttg tcgattaatg agtttaacga tgttaagtta gctacttctt
     8221 catctgttaa tggacggact ttatttcctg catgtgtatc tttattatgt ctagtatcac
     8281 gaacgtaata attttctatt tttctaaacc attttttctt aacatcatta ttttgagcta
     8341 atatcgcttt tgcttccatc gcatcaagtg tatacattac atcatatgat ccatgcatat
     8401 aactttgaag cgcctcatcc gaatcgaaac gttccaccgg attatatgta tgcaatctat
     8461 tcaaatcatc tttttctgct ttatataacg tatttaaagc taaaatatga gaatttacac
     8521 tatctacaga ttgcagtaaa ccaagtgcgt ataactccgc tcccaatcct tcacgtctac
     8581 catttccttc aaagtagatt gcagaatcag aattatgaac catttcatga gtataaaccg
     8641 acgttccata agcatctaat aatctatcta acacaaagtg cgttaaactt ccattcgcat
     8701 acgctcctgc actactatta tactcatacc atttcccaac aggtccgaag aattctttaa
     8761 tagagccgat gtttttatcc gttaaccttg cccaataagt tcttcctgtc tcatctttta
     8821 cattgaatcc atcataaact atcacagaac ggaaaagttt ttcttttgaa gcactgtcaa
     8881 gaagattgta ccaaatatca taatggtctc tatgcctttt cgctgctata tcaactctat
     8941 ttcttacata agttcgtaaa gcatctcctg aaagaataac tccatccaca ctatcacgat
     9001 atctttcata cgaaccgaat gcaagtgtag acatattcga tgaaatatac acagattctt
     9061 caggtaaagt tagtagtggt aataacatac tcttatgccc ccaacttggt gctgatattc
     9121 tatcgtaaac tcctaatgaa tattttctat cggctgttgg tgattcttgt ttttctcgta
     9181 cttctgcaat atcagacttc atttcgacta tatatgcctt tgtattttct ttaaaccact
     9241 cgttatttgt tttgtttggt aagaacagtt ttctatacgc ttctacgaag tcaaagactg
     9301 aatcttctcc ttttaccgat gcaagtttat tcgcatataa acctacagta tttgaagctc
     9361 tcaggttatc tagtccacta tttcctaatg cgacaatagt atccaacgtt gaagtctcat
     9421 tatttccgtt aaagtcaaac ttgtacgtag ataaatcttt tgtattcatt ttaccataat
     9481 taatatcgta ccaacggttc atataagtaa gacctagcat aaatgcttct ttgttatttt
     9541 tgattttctc acttacgtat tcaactacac cgtctcctgt agtattgatt gatttatcca
     9601 tcgctaatac ttttcttagg tgttctgcta tattagcttt aacttcttca aattgtctat
     9661 ctaagtatag gttatctaag gctgcatcat tcgctgctcc tagtactttt ttagtagctt
     9721 ctgagttaag tgttacattt tgcaagtcgc ttagtacgtt attcgttatc gctgtatagt
     9781 ctgaaacaaa tgcttctggt gtgaatatat attcttttcc tgtaacattg tattcgatta
     9841 cttgactgtt tatgaagttt tctttgaatg ttacatctag gtattctact gtattatctt
     9901 tgaaatgtaa cataacttta tttattgaat ttttcttatt attaatatcc gttactactt
     9961 catcatcttt catcggcaca acatctaaca attctgtagt gtaaagttta tctgttgtcg
    10021 ctactttgtt accatagtga actactaggt ctttattgta gaatggcatc agtttttcta
    10081 tgttgctata agctactttt ctttcagctt ctgctttatt tagtcttgta taatcaactt
    10141 ctcttagatt acgttttaaa tcttgcccag tatcatcaag agttactgtg attccataat
    10201 cagcaacttt cgcgtctatt tggtcttttg ataattttgt agcgaatctg tctgcttttc
    10261 tattatcaac tgatgtactt gcatttttca catctgctgc tgcgtattga tcaccggtga
    10321 taacataacc atctccaaca tctacgttac tcacaacatt atttactcga ccgttttgcc
    10381 acgtagatcc tactattcct ccgactctag aatatccttg accatttcgt atttctccag
    10441 tagcaaccga attagatatc aatgcaccat tttctaatct acctactatc cctccagctg
    10501 tttggttatt attgcgtgca ttagtagaga ttaaggcatc taccctaact ttattaactc
    10561 tcgaactatt tcctgttata ttacctacta ttcctccagt atcattttta ttactgtcct
    10621 ggtgatttgc gataagtttc cctgtaaacg agctgttttc tatcactgta tttgttgcgc
    10681 tcgctactaa tcccgcaaca gatttcgcac ctgagatttt tccttctact gcaacattat
    10741 taatattcgc gctattcgct gccttcgcca gcgctgcgac attttcttta ctatcagcag
    10801 aaacagtttt aatatccaaa tctctaactg tagcaccatt taatgtatca aataatggtt
    10861 ttttcaaatc ataaatggca tacgattttg ttccatcaga accgatcaag ctccctgtaa
    10921 atgcacctgt gagataactt gtctgcttat cgcctaagct cacctcatct gcggtcatat
    10981 ctgaagccaa tgtatagaca ccagacagat tgctttgcat ggctgttacc agctgtttaa
    11041 aggatgtgta aactcctggt tgctctgctt tagatttagc tacagtaaat gtgtaatcat
    11101 ctttgtaacc gtctgtacct tcttcgacaa gttgatcaac ggctaccgtc actttatacg
    11161 ttccatccgt attttctgta atagatttta caggtaggta catttctttg aagcgatctg
    11221 atttcacttt tacaaagtat ttagccgtat cagtcggcgc ttcacttaga cttaaatatc
    11281 tacgataacg atcattttct ttaccgtata attctactga atcaatatct ttaatctcta
    11341 ttttcttata ctctaattgg aaatcttgag ttgatgtttc agtattttcc tcattatttt
    11401 cacccaaatt ataagttagg tgtgttttaa ctgtatacgg tgtgtagtaa tctaaacctg
    11461 atattacttg ctctttggca ggattttcta tatccacctc tttaactagc ttgtctccat
    11521 ggaaaacttg cgtttttgca gaaacatatg ctgaggtagt gtctattaag ttataactta
    11581 cagttataga ttttttgttc tcaacttttg ttaagtttgt aatttctact gtaggtttaa
    11641 ctttcacaag tgttcctact ttaacgactt cgttgaccgg agctacttca gttcgtgaca
    11701 cttctttagt ttctacgaca ttaccattta cgatgtagtc ttcatattga attgtacgtg
    11761 tccctgcttg cccttgtcgt tcaatcttac gacgattttt cagaagtgtt ggatcctgaa
    11821 tttcttctgt tgtataagga atattctgga tttccgttct atttcgtgta gtgacctcta
    11881 aagccggaag ttcttcttct actgccgctt cgccctcatg ttcgggttct tgtgtgcctt
    11941 ttgtcgctac cggttccgtg tactctagag tctcttcgcg gactgtagct ttgccctcat
    12001 gacctggctc ttgcgtgcct ttcgttgcta acggttctgt gtaagctggt tcttcctcgc
    12061 gaactgcagc ttcaccttca tgtccgggtc cttgtgtacc tttggtttct agtggcttag
    12121 tgtagactgg taagtcttca cggactgcgg cttcaccctc atgaccgggt tcttgcgtgc
    12181 ctttggtttc caatggaagt ttatactctg gtcgatcatt tgtcgtcgcc aatacttcct
    12241 cttccgcact ctgcaccgtt gtagcagaca caggatttcc ttgttctggc actgttggtc
    12301 gaactacaga ttctcctttg tgatccggat tctgctcaac ttgacttgcg aatgaatcat
    12361 tagaagatag attgtctgct gctatagaag atttttctga aagtccatca tcccctgatg
    12421 cttcaccttg taaactaacc ttcccctgtc cttggttcca ttctaaatca gctgaatgaa
    12481 ctacatctga tgtttttgta gagtttggtt gactatctct ttgagcagag tatttcccat
    12541 caactgtcct tgaaagctct gtattatcct gtttcttagt tttgatataa ccaatatatt
    12601 gataaccttc gattttcaga ggctctggta aatgttcccc gactccgata gaaagctgac
    12661 tattataggc agataaaatc tggctggtca acccaaaagc actggccggc aacaattgaa
    12721 ctcccatgct agtcaacagc agaaaatgaa caagtcgttt ctttccattt tcccttttag
    12781 aaaccaataa aactaacaag ctcaatcctg cagtaaaaag gaaagtacca acagttgggt
    12841 taaaacctgt attcggtaaa aactgttgag atctataaac caagtaataa gtatcatctg
    12901 attcttcagc cagttgtgga agggcctcta ccagcaagga tttttcctcg tctgtcaatt
    12961 taccctcggt catatactta taatgaattg gactttccat attatcggcc gataccgatt
    13021 gaatcccttg actcatcaaa aagaaactag atacagtaac tgataccaat cccactgaca
    13081 actttctcat cgagaaacta tggcgtttct caccaatgct ttttcggctc atattaacct
    13141 cgctttttct atattcttta tatcaatcta tattttatag cataaaagta taaacataaa
    13201 aataatatag tatggaattt tctgagtact tttcaacaat tacttatcat tatacaataa
    13261 atcgatagaa atttctattg aaatatactt aaaaatattc tgcatactat aaaaaataca
    13321 gtaaattata acgataaaaa acagagataa catctcaaca agtaagtgtg gacttcagac
    13381 taattacagc attttttaaa ttagattacc gcttatgctt ttaatgggct ataaaatatt
    13441 agcttacaat agaaaagtct gaaattgagg cgacaagaat ccaatcttta taaatcaaaa
    13501 gaggccaatg ttcgccatca acctctttct tatcgttcat tctttttgct aagtaagatg
    13561 aatgctttac ctatggcctg agcctagttt acccattcac cattaccatt tacacggtaa
    13621 ccatctggtg ttgttgtgct cacagccaaa gctcctgaac cgtaggcata gtaccagtgt
    13681 ggtccgactt taaaccaacc tgtcttcatg atacctgctt cgtcaaggta ataccaagtg
    13741 ccattttcct tgtaccagcc tgtcttcata gctcctgagc cgtcaaagta gaaccatctg
    13801 ctaccatctg ttccccagcc tgtaaacata gcacctgaat tgctcaagta ataccagcta
    13861 ccagaaaatt ttacaaatcc agtctgcatg acacctaagt cattcaaata gtaccattta
    13921 ccatctgttt tcacccaacc tgtcttcaca tcaccagact catagaaata ccatttacca
    13981 ttagattcca cccaaccaga ctgatcagac gtagacgctc taaaatcttt cagtggtttt
    14041 tctacaaccg tagctttagt tttaactgtt gaaaggtttg aggcagtcac ttctgtacac
    14101 tgaacagcag aaccatatct accagccaat tcctctgaag aagcatcatc acctagagtt
    14161 tgagcaattg taatagcttt gtattgattg ttaggatttt taaaagctgc catccccatg
    14221 tgtgtaaatt tagggttaat tagcgactca tagtgaccag atttcccgtt gtctgaacca
    14281 ctattttttt ctccacataa tctgcttttt cagcacgcca ttgttcaata gcttttagaa
    14341 aaccgtcatg attccatgcc aaattttctc ccattatact attagaagtt ggaaaggcac
    14401 tccaaagatc tttgctagaa agacgggtat gatccatggt tatagatgct tctgtagctc
    14461 tggcaaaagc tgccttttct aggtcagttg accatttgat agggacatac ttatctacca
    14521 aaccttcgtc agccgcttct ttacagatag cattgatggc atccaaaata gattgttgat
    14581 gaggagccac aaattctcct ttgattccaa ccaaaacatt gccactagaa ggttttagca
    14641 cctctgaggt caatacattt tcatttttac catcagtagt ttgtgttgcc acaagtctgt
    14701 cgttcgcaaa aacatcattt gtcaaaactg ctccagccaa ggtcaaagcc aaggcactag
    14761 caaatacaat tttcttcgtt tctttcttac tccttattgt agtttgaata ttatattaac
    14821 agatagcttt caacgcttag ttatatcata ttttcctact atttgtctct gcgtacctat
    14881 tcctagctcc caaaagtagg cgcaatgact cttttacttc acaacaagtt cataacgtgt
    14941 cttactggtg aaggtttgac cagctttaag aatgacttgg cctttaaggt cactgtgaat
    15001 ggcatctggt aaagcttgcg cttcaagagc aatcccattg tgctgtagca ttggctgacc
    15061 tcctatgatg acactttcat ccacaaagtt tgctgtgtag accacaaagc aaggagcttc
    15121 tgtcttgaaa agcaggaagc gacctgaatt ttggtcataa aggaatccag cattgtcatg
    15181 gcctgcagga agggcaaatg gatgatccaa acctgatgcc agctggattt gctcatcttc
    15241 ttctgcaaag atatccttca acaaggtacc attgtagacg tgtttgacca catcacggtt
    15301 ggcttctgga gttttggcag gaacaccgtc aggagcgatt gagtaaatgc cctctgtgtt
    15361 tagttggaag acatgacggt caatcgtctg cgtgaaatca ccagacaagt tgaaatagct
    15421 gtggttggtt ggattgacca gcgtatcctg atcggtcgtt accttgtagc tgatttcata
    15481 ggcaccagtt tcttccaagt gataactgat ccaaatcttg agatttccag ggaaccctcc
    15541 tgtcccatct gtacgctctg tgtagagagt caagccatga tcgcttactt cttcaacttc
    15601 aaacaagctg gaatcccaac cagttgaacc actgtgatta cagttgctag cattattaac
    15661 ctcaaggtca taggtcttac cattgagctc aaaggtcgca cctgcaatac gacccgctac
    15721 aggacctaca cttgctccat gcttgggact attgcctaca taactatcaa agtcatcaaa
    15781 tcccaagata acattggcaa aatttccagc cttgtcaggt gcgacatagc gcaagatagt
    15841 cgcaccataa gtcataacct caagttggta gccaccgtct gtctcaaatc gataggccaa
    15901 gacatcctca ccctcaacat ttccaaatac acgctctgtg tatgctttca ttctgttctc
    15961 cttttactat ttctctcaag caaacaaacc atagaaagcg tactgacaat ctatggttta
    16021 tctgataatt tacaaatcct cttgtcaaga attcataaac actgtcttac ttttgatatt
    16081 cgtgaattat gacaccttgt actacacggt ttactgtacc tgtaggagac ggtgtatctg
    16141 gtttattttc taccttgagt gaagtcaata aagcaaagag ttgggcataa acgatgtaag
    16201 ggaagacacg gtaaatatca ttcaagacac cgccacaacc aagggccact tctttgacat
    16261 tttcaagacc aaaagcttga tcactcaaaa gcacaacacg acgagcaatc tggtcaccag
    16321 caacttcacg aaccaagtcc aagtcgtact tacgagtgta gtctgtcgtt gtaccaaaga
    16381 ccaaaacaac tgtattgtcg ttgataagag attttggacc gtgacggaag ccaactgggc
    16441 tttcatacat ggtcgcaact tgaccagcag ttaattccaa aatcttgagc tgagcttcat
    16501 gagcaagtcc aaagaaagga ccagcgccta gatagatgac acggttaaag tctaaatcaa
    16561 cgagctcttt gacatcttct gccttgtcta aaactttacg ggcaagacta gatacaactt
    16621 caaaacgttc agacttaaca gcaaattctg taggatcaaa gaccaagaga gttgtcaaca
    16681 tcatagacgt aaagctagaa gtcatggcaa atccagcatc attagagaca gctggttgca
    16741 agagcaagag attacgatca tcaccgtgag cttgaagagc caatttacca tctgctgcac
    16801 aagtaatcgt cacttgataa agctcatcca ccaaggattt ggccaaatca acagtcgcca
    16861 aactttcagg cgaattccca ctacgagcaa aagacacaag gacagttgcc acatcttttt
    16921 tcaaataggt tgctggattg gcaacgatat ctgttgtcgc aatagcattg aaattccatt
    16981 tgcgttcgtc atagacttcc ttaaaataag gtagcaaggt atctcccaca taagcagaag
    17041 tcccagcacc tgtcaagata accttaatat agtcatgttt atcagcgatt tcttgtagga
    17101 aggctgcaat ttcttcacgt tttgcttgat aaaattcaaa agcttctctc catacatcag
    17161 gctgttggta gatttcacgc gtagtgattt ctgcacccaa ttcgagcaag tcttcttttg
    17221 tataatgtag cattgagttc ctctttttct attaaatatg ggaatgggag taagctacat
    17281 tcccatgtat attctatata aaatgctcta acgattttca cgttgtcaca tgaattgaat
    17341 cgagttccaa ctaaaatctg taggaaacta gccgcaggct gctcaaagca ctgctttgag
    17401 gttgccggat aagactgacg aagtcagctc aaaacaccgt tttgaggttg ccggataaga
    17461 ctgacgaagt cagtaacata tacctacggc aaggcgacgt tgacgtagtt tgaagagatt
    17521 ttcgaagagt attattcatc ttcgtcatca tcgaagcccg ctaacaggtc attaactttc
    17581 acaatgcttt ctgcagcacg gctcttgtag tccgcatctg cgcctgtaag gctcgcattg
    17641 ataaattcaa tcaccattgg aagattcatc cctgcgtaaa ggtcaatatc acgaccttcc
    17701 atgatcaagc gactcaccac attacaaggt gtcccaccga gaagatccgc aaagactagg
    17761 aaatcatcca atccttcaat aacagcttca aatttagcag taaattcttc tgggccatct
    17821 tctggaagaa gagctactgt gtaaatgttg tcttgtgggc ccataatcat ttctgtgcta
    17881 cctctaagct cctcacagaa gcgaccatgg ctcaccaaaa ttaatgattt agtcataagg
    17941 aattacattc caagtgcaaa gtgaccaagg gcagaaagag ccaaagcaag tacgataata
    18001 ataccgatag ctttagtaga gttcatacct ttcttaccaa gcaaccagaa gataaaggca
    18061 gtaaagattg ctggaagcaa acgtgggaag atttggttca agatgtcttg gaaatcaatc
    18121 atcttttcac cgattggcaa cttgtaagaa atttcaaagt taatcactgt tgctacaaga
    18181 gcacccatca tgaagacacc aagtacagat gcagcgtcaa tcaaagctgt caaggtactt
    18241 tgcatgttgt tgataaggtt aaccccttct ttgtaagcaa attccaactg tttccaacgg
    18301 aagatgtcat acgctactgc aactgcaatc caaaggaaga tcccccaagg ttggccagcg
    18361 atagccatag ttgctgcgac tgaccccatg atagcaggta caagtgaacc aaagattgta
    18421 tccccaagag gagcgaatgg tcccatcaaa cctgtcttga taccgttaac ggcgtctttt
    18481 gaacctacac catctttttc ttccatggca aggtcaaaac cagcgataat ggtatggaag
    18541 aatggtgaag tattgaagaa ttgagtatga actttcatca tttctttcaa ttcaggagtt
    18601 ccatcaccat acattttacg caactgaggc aagatcatgt aaaggtaacc agaagcttgc
    18661 atacgttcgt agttccaacc taattggaaa gtaaacaagc tacgtttgtt gatttgatta
    18721 aaatcttctt ttgtaagttt gtaattagaa ttcgtcatct tcgatttccc cactttctga
    18781 tggtgtagaa ggtgctgcta cagctacttt ttggctattt ttgaagtgaa gcactgcaag
    18841 gaaaatacct acgatagaaa taccaatcat agacaaacct ttgaagttgt tcacgaaacc
    18901 aattttttca gcaacttcag caggaagagt acctacgata ccagcaacag cgccaccaag
    18961 acctgttaca tatgagtaaa gaacagtcaa catagctgtc aaaccaaatc ccatagcaag
    19021 gtagtgaagg ttacgtttaa ctggaaggta acgaagcaag attgcaaatc caagacctgg
    19081 aagcatacgt cctgcaagtg tcaagccatc tgcaacccat ttgtaggctt caacgaagtc
    19141 tactactgat tgtacaaagg caccaccaaa agcaagggca aagaagactg gaagggcacg
    19201 agatagagcc cacggaatcg caccaagcaa gtagttgcgt tcaatacctt tatagtcaaa
    19261 gcgttcgatt gcagcatcca cacggtgagc gaagaaggta gtagtcatac gaccaagaac
    19321 gtcgaagtaa gtcaagagag ctgctactgg tacagcgatt gtagtaatgg caagcggtgc
    19381 atcaattcct tgtgaaacag agaaggctgt cgcaagaacc gcaccagaag ttgcgtcgat
    19441 acgagaagca ccaccgaagg taccaacccc aagaacgaac agttgcaagt taccaccgat
    19501 aagtaaacca gtagtcacat ctcccatgat taaaccagta atgaaaccag caaatacagg
    19561 ggaacctgca gatgaaacga tcgtcaactc atcacagatt tgataagctg agtacaaagt
    19621 gagaagtaaa atttgccacc attgtatcat aacaatgacc tcctaaaaat ttttttccta
    19681 ttttaataag ctcaaaaagt ctgaaattgg atcatttgga accatctgag cagtaagttt
    19741 aacacctttt tctgccagtt tgtggaagtc ttccacatcc ttgtctacta cgttgataga
    19801 acgtgtaata gaacgagttt ctggtgtttg agacatattc ccaacattaa gggtttcaag
    19861 tggtacacct gcttctacca aaccaaggaa gcggtctggt ttacgagcca cgataaagag
    19921 acgttggcta tcgtatttgc cagcaagaat attggctgca gctttctcaa ctggcaaaat
    19981 actcaatttc acacctggtg gtgtcgcaag tttcaaacca ctcttttcaa tatcgttgtt
    20041 gacaacttcg tcgtctacaa ccataatgcg tgaaacattt agttttccag cccaaagatt
    20101 ggctacttgt ccgtggatca aacgtccatc aatacggcat cctacaattg tcataagttt
    20161 tcccccttta tatgttttag tgtaggttta cgagttaaat gaatctcttc tttatattga
    20221 ccttctgttt caaagataat gatgcggttg gcaccttcct tgagatagct atgagggata
    20281 taaagtgaga gagttgggcc aacgttccaa aaacgtccta gattctgccc attgacaaag
    20341 gcaaccccct taccaaactc agacaagtct aggtaagtat cttttggctc ttcgactgta
    20401 aagtcataag cgtaaaaggc tggttgtcct tgagtccatc cttttgaaaa atcaattttc
    20461 tcaggattgt ctagtgggag tggatagtgt ttccagttta gtaagaaatg cagatcctta
    20521 cagacccctg tccgaattcc cttacgttgc gtatccgcta agaacttatg cccatagttg
    20581 acacgcccca tattttctat caagatatct aacctagata gccctttctt tttaccttga
    20641 taaaaaatat cttccccaat ctctgtctga tattgagttt taacccactg accatcgaca
    20701 tacagctggg ccctatctcg accatcaatg atacgaagtc tttcttcttc tgcatcccag
    20761 tttgtttctg ttcgataaag taggtagcca taactttgtc ccagctcctc catcttttga
    20821 ggatagagac tttctacagg acttgacaag ctatctaagg tttcaaacaa agaaactttt
    20881 tcaactagtg gaatagcatc caactccata ctctctttgt agagtggttc caactgcgga
    20941 tactctgaaa aatgtgttgc catcatcttc ttgactgcaa gatatttagc agttggattt
    21001 ccttcttcat ccagaagggc atcgtaatca taagacgtaa cttgtggcag gtccaaagtt
    21061 cctcgagctg agcaaccatt catgaaacca aagtttgtac caccgtggaa catgtaaaga
    21121 ttgatagagc cttgttccaa aacctctcga actgcatctg ccaattcctt aggatcccgt
    21181 gtgataatcg gttctttcca gcgattgaac caaccatccc agaactccat acacatgagt
    21241 ggccatttct taccatgttc atcaaagaat tcctgcatct gcgaaaagtt gtaaggtgcc
    21301 ttagaaccaa agtttcctgt tacaaagagg tcctcttcaa ttaaggttcc agctttcaga
    21361 gtagctcgcc atggaccatc tgatgtaaag aggggacagg ttacgccaca ctcttccatt
    21421 agctgtcgaa tcgctctcag gtaagcctta tcttctccgt aagaaccata ctcattttca
    21481 acctgcatca tgagaatatt gccaccattg tccaacaaac gaggcaccag tcttggcaat
    21541 aactgatcat agtagcgacc aactgcctcg atatatgctg ggtcggatga gcgaattcgc
    21601 atgttcttgg tcaagagcca agctggtaag ccaccgaatt cccattccgc acagataaat
    21661 ggagacggac gcacaattgc gtagagaccc aaatcctgcg ctatttggag aaatttctct
    21721 aaatccagat caccttcaaa atgaaactca ccttcacgag gctcgtgtaa attccaagca
    21781 acataagtct ctaccgtatt aaaaccaaga gccttcaagt tatagagcga atgataccaa
    21841 tcctctggag gaaccctaaa ataatgaatg gcaccagata aaatcttaaa tgattttcca
    21901 tcgagataga aatcatctcg tatctcaaat cgtgtcataa aactaccttc cgaccgcgaa
    21961 agtttgcgct ttcatttgtt gttatattaa ttataaacca atctgtttga attgtcaata
    22021 gaaattgtcg ggatatttac tgcattttta ctattataca cacattcaat tagtttcaaa
    22081 catttttaga cccatttcaa acgctcttta aattcggaat ataggaccta aaataatttt
    22141 gtatagaata cattgataaa atatgagcaa tccctatatc gcttaatttt tcagactatt
    22201 attctaattt tttattcaaa agactactat ttttttcgct tttatggtaa aattttctat
    22261 ggagaaggaa aatagaggta aaaatatggc aattcccaaa tatcaataca taaaagacga
    22321 attaaaaaat aaaatcatct ctgggcagtt tagcagtgga gataaatttt acactgaagc
    22381 agaactcatt tcaatgtacg atgtcagctc tatcacagtt gttcgcgcct taaacgacct
    22441 tgccaaagat ggctatattg tccgccaaca aggaaaagga accttcgttt cacgtgcacg
    22501 caaacacaag cttgtagagt tttcagatat tgaactcttc aatgctaaag atgataaggt
    22561 aactgttctt tcaattgaac gcggaaacaa gcttgtttac ttggaaaaat tgggtctacg
    22621 tggcgatcaa ttctactaca agattgaacg tatccgcgaa tcaaacggtg tcgtttatat
    22681 ctaccataca tcctacatcc cagaacaata tatcaacgca aattatccaa accttgaata
    22741 ctatagttct atctataatc gtttcaagtt agactaccac attcacatga atgatgaaca
    22801 ctttgaagaa atcaacgaaa tagtctttcc aactccagaa catgcggctt cagtcctcgg
    22861 agtcgatgaa caattcccta ctgtcctaca aactaaaatc accaaactcg aatcaactgg
    22921 ccaagtttta gaatacagtg aaacttacaa acgatctgat tactacaaga ttaaatttat
    22981 ctcatgtgac cgtgatcact aagaagaaag cctgagctaa tcgcttgggc tttttctatg
    23041 cttattatac cacaccaaaa aggtagcgct tacctatttt tggaaaattc tataatttgt
    23101 ggaatatttt atagaaatag aaccaaaaat tatactagat atatatacgt attttttccg
    23161 accaatctga aatcttaagt ttaaatttta tattttttta tacttattat agttttttgt
    23221 catctcctct tgactctcgt taatataaga aataaaataa aggcgttgat ttatataatc
    23281 gctatcaata taacaatgca atcaggaggt tttgcaatga aacatgaaaa acaacagcgt
    23341 ttttctattc gtaaatacgc tgtaggagca gcttctgttc taattggatt tgccttccaa
    23401 gcacagactg ttgcagccga tggagttact cctactacta cagaaaacca accgaccatc
    23461 catacggttt ctgattcccc tcaatcatcc gaaaatcgga ctgaggaaac acctaaagca
    23521 gtgcttcaac cagaagctcc aaaaactgta gaaacagaaa ctccagctac tgataaggta
    23581 gctagtcttc caaaaacaga agaaaaacca caagaggaag ttagttcaac tcctagtgat
    23641 aaagcagaag tggtaactcc aacttctgct gaaaaagaaa ctgctaataa aaaggcagaa
    23701 gaagctagcc ctaaaaagga agaagcgaaa gaggttgatt ctaaagagtc aaatacagac
    23761 aagactgaca aggataaacc agctaaaaaa gatgaagcga aagcagaggc tgacaaaccg
    23821 gaaacagagg caggaaagga acgtgctgca actgtaaatg aaaaactagc gaaaaagaaa
    23881 attgtttcta ttgatgctgg acgtaaatat ttctcaccag aacaactcaa ggaaatcatc
    23941 gataaagcga aacattatgg ctacactgat ttacacctat tagtcggaaa tgatggactc
    24001 cgtttcatgt tggacgatat gagcatcaca gctaacggca agacctatgc cagtgacgat
    24061 gtcaaacgcg ccattgaaaa aggtacaaat gattattaca acgatccaaa cggcaatcac
    24121 ttaacagaaa gtcaaatgac agatctgatt aactatgcca aagataaagg tatcggtctc
    24181 attccgacag taaatagtcc tggacacatg gatgcgattc tcaatgccat gaaagaattg
    24241 ggaatccaaa accctaactt tagctatttt gggaagaaat cagcccgtac tgtcgatctt
    24301 gacaacgaac aagctgtcgc ttttacaaaa gcccttatcg acaagtatgc tgcttatttc
    24361 gcgaaaaaga ctgaaatctt caacatcgga cttgatgaat atgccaatga tgcgacagat
    24421 gctaaaggtt ggagtgtgct tcaagctgat aaatactatc caaacgaagg ctaccctgta
    24481 aaaggctatg aaaaatttat tgcctacgcc aatgacctcg ctcgtattgt aaaatcgcac
    24541 ggtctcaaac caatggcttt taacgacggt atctactaca atagcgacac aagctttggt
    24601 agttttgaca aagacatcat cgtttctatg tggactggtg gttggggagg ctacgatgtc
    24661 gcttcttcta aactactagc tgaaaaaggt caccaaatcc ttaataccaa tgatgcttgg
    24721 tactacgttc ttggacgaaa cgctgatggc caaggctggt acaatctcga tcaggggctc
    24781 aatggtatta aaaacacacc aatcacttct gtaccaaaaa cagaaggagc tgatatccca
    24841 atcatcggtg gtatggtagc tgcttgggct gacactccat ctgcacgtta ttcaccatca
    24901 cgcctcttca aactcatgcg tcattttgca aatgccaacg ctgaatactt cgcagctgat
    24961 tatgaatctg cagagcaagc acttaacgag gtaccaaaag acctgaaccg ttatactgca
    25021 gaaagcgtca cggccgtaaa agaagctgaa aaagctattc gctctctcga tagcaacctt
    25081 agccgtgccc aacaagatac gattgatcaa gccattgcta aacttcaaga aactgtcaac
    25141 aacttgaccc tcacgcctga agctctaaaa gaagaagaag ctaaacgtga ggttgaaaaa
    25201 cttgccaaaa acaaggtaat ctcaatcgat gctggacgca aatactttac tctgaaccag
    25261 ctcaaacgca tcgtagacaa ggccagtgag ctcggatatt ctgatgtcca tctccttcta
    25321 ggaaatgacg gacttcgctt tctactcgat gatatgacca ttactgccaa cggaaaaacc
    25381 tatgctagtg atgacgttaa aaaagctatt atcgaaggaa ctaaagctta ctacgacgat
    25441 ccaaacggta ctgcactaac acaggcagaa gtaacagagc taattgaata cgctaaatct
    25501 aaggacatcg gtctcatccc agctattaac agtccaggtc acatggatgc tatgctggtt
    25561 gccatggaaa aattaggtat taaaaatcct caagcccact ttgataaagt ttcaaaaaca
    25621 actatggact tgaaaaacga agaagcgatg aactttgtaa aagccctcat cggtaaatac
    25681 atggacttct ttgcaggtaa aacaaagatt ttcaactttg gtactgacga atacgccaac
    25741 gatgcgacta gtgcccaagg ctggtactac ctcaagtggt atcaactcta tggcaaattt
    25801 gccgaatatg ccaacaccct cgcagctatg gccaaagaaa gagggcttca accaatggcc
    25861 ttcaacgatg gcttctacta tgaagacaag gacgatgttc agtttgacaa agatgtcttg
    25921 atttcttact ggtctaaagg ctggtgggga tataacctcg catcacctca atacctagca
    25981 agcaaaggct ataaattctt gaataccaac ggtgactggt actacattct tggtcaaaaa
    26041 ccagaagatg gtggtggttt cctcaagaaa gctattgaga atactggaaa aacaccattc
    26101 aatcaactag cttctaccaa atatcctgaa gtagatcttc caacagtcgg aagtatgctt
    26161 tcaatctggg cagatagacc aagcgctgag tacaaggaag aggaaatctt tgaactcatg
    26221 actgcctttg cagaccacaa caaagactac ttccgtgcta attataatgc tctccgcgaa
    26281 gaattagcta aaattcctac aaacttagaa ggatatagta aagaaagtct tgaggccctt
    26341 gacgcagcta aaacagctct aaattacaac ctcaaccgta ataaacaagc tgagcttgac
    26401 acacttgtag ccaacctaaa agccgctctt caaggcctca aaccagctgc aactcattca
    26461 ggaagcctgg atgaaaatga agtggctgcc aatgttgaaa ccagaccaga actcatcaca
    26521 agaactgaag aaattccatt tgaagttatc aagaaagaaa atcctaacct cccagctggt
    26581 caggaaaata ttatcacagc aggagtcaaa ggtgaacgaa ctcattacat ctctgtactc
    26641 actgaaaatg gaaaaacaac agaaacagtc cttgatagcc aggtaaccaa agaagttata
    26701 aaccaagtgg ttgaagttgg cgctcctgta actcacaagg gtgatgaaag tggtcttgca
    26761 ccaactactg aggtaaaacc tagactggat atccaaaaag aagaaattcc atttaccaca
    26821 gtgactcgtg aaaatccact cttactcaaa ggaaaaacac aagtcattac taagggcgtc
    26881 aatggacatc gtagcaactt ctactctgtg agcacttctg ccgatggtaa ggaagtgaaa
    26941 acacttgtaa atagtgtcgt agcacaggaa gccgttactc aaatagtcga agtcggaact
    27001 atggtaacac atgtaggcga tgaaaacgga caagccgcta ttgctgaaga aaaaccaaaa
    27061 ctagaaatcc caagccaacc agctccatca actgctcccg ctgaggaaag caaagctctt
    27121 cctcaagatc cagctcctgt ggtaacagag aaaaaacttc ctgaaacagg aactcacgat
    27181 tctgcaggac tagtagtcgc aggactcatg tccacactag cagcctatgg actcactaaa
    27241 agaaaagaag actaagtctt ttcgataaaa aataaacagc gagattgaag ctcgctgttt
    27301 attttttaat taatcaccta gtccaagacg ttcaaagata tcatccactc gtttggtgta
    27361 ataaactggg ttgaagattt catcgatttc ttcttgagtg agacgtgatg ttacttctga
    27421 atctgcctca agaagtggtt taaagtctac ttggttgtcc caagagtagg ctgtttttgg
    27481 ttgcaccaag tcataggctt gctcacgggt catgcctttt tcaatcaatg tcaacatagc
    27541 ccgttggcta aagataagac caaaagtcga gttcatgttt cggatcatat tttctgggaa
    27601 gactgtcaag ttcttgacga tatttccaaa acggttgagc atgtagtcaa tcaaaatggt
    27661 cgtatctggt gtgatgatac gctcagctga tgagtgagaa atatcgcgtt cgtgccagag
    27721 agcgacgttt tcataagccg taatcatgtg accacgaatg acacgcgcca gaccagtcat
    27781 attttcagaa ccgattgggt tgcgtttgtg aggcattgct gaagaccctt tttgcccttt
    27841 agcaaagaac tcttctactt cgcgttgctc agatttttgt agaccacgaa tctcagtcgc
    27901 catacgttcg attgaagtcg caatgctggc aagaaccgca aagtactcag cgtgaaggtc
    27961 acgaggaagg acttgtgtag agatttcttg ggcacggatg ccaagtttat cgcagacata
    28021 ctcctctaca aatggtggga tattggcaaa gttcccaacc gcaccagaaa tcttaccagc
    28081 ttctacacca gcagctgcat gctcgaaacg ctcgatattg cgtttcattt cgctgtacca
    28141 agttgccaat ttaagaccaa aggttgtcgg ctcagcgtgc acaccatgag tacgccccat
    28201 catgatggtg aacttgtgct ccttggcctt gtcagcgatg atattagtga agttttcaag
    28261 gtcacgacgg atgatgtcgt tggcctgctt gtagaggtaa ccataagcag tatccaccac
    28321 gtcggtagaa gttaacccat agtgaaccca cttgcgctct tcaccaagag tctcagaaac
    28381 cgcacgcgtg aaagccacca catcgtggcg cgtctcctgc tcaatttcca aaatacggtc
    28441 gatgtcaaag tccgccttct tgcgaatcaa agccacatct tccttaggga tttcccccaa
    28501 ctcagcccat gcctcgtcag agaggatttc cacctcaagc caagcacggt atttattttc
    28561 ttcactccaa atattcgcca tctcagggcg agagtaacgg ttgatcatgt gttaattttt
    28621 cctttcttct taagctgttg ggaataagct atctaggtaa accaagattt ctactcaaac
    28681 tcctcttttt caataaacac agacgggtaa tgatctagtg tattcaaatc cgtatccagc
    28741 ggtacatcat agatagctaa ataattttcg gggtattgtg cagctagttc ttcatattta
    28801 gcttttacct tatcttggtc agcactggca tacaacactt caacaactgc tccagtctta
    28861 tccttttcaa taaatgtatt aacgataatt tgtatcatag acttgtccta aaaatcaatc
    28921 ccttccccaa gctcatccac actatccggt acatcactaa acaaggtcac atgtcccatc
    28981 ttgcggttgt gcttcgcttc tattttacca tacatgtgga ggtgggcgct tgaattttct
    29041 gtcacatatt gctcagcagc ctcgacatgc tgaccgagga cattaagcat aacggctggc
    29101 gcatggagtt tgatgactgg taatggtgct ccgagaacac cgagaatatg ggtgtcaaac
    29161 tgagagaaat cacaggcttc aatagaatag tgcccagagt tatgtggtcg tggggcgatt
    29221 tcattgacaa taacgtcatc atcagtcgca aacatttcca cacagagagt tccagacaag
    29281 ttgagttgtt ctgcgattcg cactgccata gctttagcct tgtctactag actttcagaa
    29341 atgcgggctg gtacgatggt cttagacagg atattgttgc ggtggatatt ttcctgaact
    29401 gggaaaaacg tcacctcctt gccatttcct gacacgatga cagaaatctc aaggtcaaag
    29461 ttgacaaatt cttccaagac gcagtctgct gagtctgcta gcgcataggc tgcttccaag
    29521 tctgcttctg aacgaataac cttttgtcca tgaccatcgt agccaccagt cgcagtcttg
    29581 aggacatagt ttttcgacaa gtcgatatct gccaagtcta ggctagaagt cacgaccttg
    29641 tagggtgcca cagtgacttg agccttgttt gacaaaaagt ccttttcaaa aatacgattt
    29701 tgcgaaatgc ggagcagatc tgttccttga gggagttgtc catccttgat aacggcatcc
    29761 aaaccgtcag cgtcgacatt ttcaaactca taagtgagga catcgcaacg gtctgccaac
    29821 tgacggaggg cgtccacatc gttataaggt gccacaatga tttccgccac gcgagaggcc
    29881 gggcaatccg ccgcaggatc cagcgcgata accttgtggc ccatgtagat agcagaaatg
    29941 gccatcatct gacccagttg accgccaccg ataattccga ttgttttaga tgagctcatt
    30001 tgacgactcc tctgcgattt ttccttgttc ttcagcaaag ttggcaagtg catccgcaat
    30061 ggacttatct tctacagaga ggagacggag ggcaaagaga gctgcgttag tcgctccagc
    30121 ttcaccgata gccatggtcg caacaggcac cccacccggc atctgaacga tagaatagag
    30181 tgaatccact ccactaagag cacgagactt gactggcaca ccaatgactg gaagggttgt
    30241 tttggcagct accatgcctg gcaaatgcgc tgcgccacca gcacctgcga tgatgatctt
    30301 gatgccacga ctacgggctt cttctgcatg tttgaacatg aggtctggtg tacggtgtgc
    30361 ggaaacaact ttcttttcgt aggctacacc gaagcggtct aggacttctg ctgttttttg
    30421 catggttgcc cagtcggatt ttgagcccat gatgatggaa attactggtt tcatttcttc
    30481 tcctttttcc tctttttcaa caatcacctt agcttgtgag ggacggcagc agccaccaaa
    30541 ggtgtctcat gcctaaattg gaaacccaag gtcttccaat ttccctgaac gattggatta
    30601 tcatccaatc gttctttcac aacggcggtg attgttctat attagctcgc taacgctcgc
    30661 aaaccatacg atcattaacg tattttgtga atttttattt ttctttttga taatggtctt
    30721 aggtgatgga ggcggaagca aaccttcggt ttcattccta aactttgagc ctacggtctc
    30781 caagtttccc cctgaccaga acattcactg ttctggtctt ttcaccacga cgaccattat
    30841 cgtgtttggc gactacggcg cgttattctt atatctttac ttaattgcct tgcttccgat
    30901 atctgttcgg tagaagagtc cttctatttt ttgttggtat agttcttggt agatgctggc
    30961 ttgggcttct ttgacggtat ctgctgtggt aacgagcata taaactcgtc cgccgtttga
    31021 gagcagtgct ctgctatttt ccgcaaactt agcccctgca tagtaggtga tgacatcgcc
    31081 ttctgtcttg gctggcaact caacgcccct ttcatagtct agcgggtagc ccttggatgc
    31141 gacaaccaca cccagagtca cacccttgtc cgtccacatg atatttggct ccttgctatc
    31201 caggatatct gtgatatttt gagcaaagtc agaggtcaag cgaggcaaga taatctgagt
    31261 ttctggatct ccgaaccgag cgttgaactc aatgactttc ggtccatcag ctgtcaggat
    31321 aagccctgcg taaagaactc ccagataagg gcgaccttct ttaatcatcc cttctagaac
    31381 tggcttgaca atggtgtcaa ccgctgtatc aactacactc tgtggtaagt gtggaactgg
    31441 cgcataggca cccataccac ccgtgttagg ccctttgtcg ccatcgtagg cacgtttgtg
    31501 gtcctgagcc gttggcatga tgtagaactt atcaccatta acaaaggcaa agagtgaaaa
    31561 ttcctctcct tcaaggaatt cctcaataac cacgcgcgca cctgagtcac caaatttatt
    31621 gtccaaaagc atctcatgag cggcttcgac cgcttgctca accgtctcag aaacgacgac
    31681 acccttccca agcgccaagc catccgcctt gactacgata ggcgcaccat gcttttcgat
    31741 ataggccttt gcttcctcga aatctgaaaa tgtgccatag gctgctgtcg aaacaccata
    31801 tttgaccatg atttccttgg caaaatcctt ggaccactcc agctccgctg cagccctagt
    31861 cggaccaaag gccttaagcc cagcttggtt aaaatcatcc acgataccag cagcaagggc
    31921 atcatctgga ccgataaagg tccaagcaac atcattggtc tttgcgaagt caatcaattt
    31981 agaatgttcg gaaatagaga tatttaccaa ttccaaacca tccagagtca tcccatcatt
    32041 cccaggagct acaaagactt tttcaacgtc ttttgattca agtaactttt tagcaatcgc
    32101 atgctcacga ccacccgaac cgacaacaag cagtttcatt cctcaacctc ttttgcgaat
    32161 tatttaccaa tattatatca aaaaagttcg ttttaatctt gtttcagtta gcattttaag
    32221 ccaaaaaagg aaagaaactg ttttcttccc ttttatcttc ttaatgtcta aaatgtctca
    32281 cacctgtaaa gaccatagtc aagccgtatt tatccgctgc ttcgatggat tcttggtcac
    32341 ggacagagcc accgggctgg atgatggcct taattcctgc tttggcgatt tcttccacgt
    32401 tatccgcaaa tgggaagaag gcatctgaag caaggaccgc cccgttcaga cgatctttgg
    32461 cttggtcaat ggcaaggcga acagaagcca cacggttggt ttgacctgga ccaacaccaa
    32521 gtgtcatgtg gtcgttggtc acgataatac catttgattt gacgtacttg atagccttcc
    32581 aagcgaactc aagagcagtc gcttctgtct cagttggctg acgtttggtc accacttgcc
    32641 agtcagctgg gctttccttg accacgtctt gattttgcac gagaagtcca ccgactacac
    32701 ctgtgtattc tgcttccact tcgctagcct cttgagcatt aaatggcaag gcaaggatac
    32761 gcaagttttt ctttttattg atcaaaatag ctagcgcttc atccgtatag cttggtgcaa
    32821 tgatgatttc gaggaaaacg ccgtgcatct tctcagctgt cgcagcatcc acctcacggt
    32881 tgaggacgac aatcccacca aagatagaca ctgggtcaga ctcataagcg tagtcccaag
    32941 cagtctcaat gttatcagcc tgaccgattc cacatgggtt catgtgtttg agagccacaa
    33001 cagttggacg gtctttgaaa tcacgaataa tacgaatggc agcatccgca tcacggatat
    33061 tgttgaagga caattcttta ccattgagct gtttggctga agcaatggag tagtctgttg
    33121 gcaaggcttt ttggtagaaa tccgcgtctt gttgagggtt ctcaccgtaa cgcatggctt
    33181 gcttgaggtc ataagtcaag gtcaactttt caggcttgct ttcacccact tgagctgtga
    33241 agtattctgc aatcaaggcg tcataagccg ctgtgtgacg aaatactttg gctgctaaac
    33301 gttggcgagt ttcataagtc gtttcaccat tggctgacaa ctcgtccaaa accacagcgt
    33361 agtcagcagg atctaccaca actgtaacac tggcatgatt tttcgctgct gaacgaagca
    33421 tagatggccc accaatatcg atattttcaa ctgcatcagc ataagtcaca tctggtttaa
    33481 ggatagtttc cttaaatggg taaaggttga ccaccacaag gtcaatgagc tcaatcttgt
    33541 tgtccttagc cgcttccaag tggctatcca agtcacgacg agcgagaagc cctccgtgga
    33601 tatttgggtg gagtgtcttc acacgaccgt ccatcatttc tgggaaacca gtcatatcat
    33661 cgatagcaat ggtatccacc ccagcattat caagggcaac cttagttcca cctgttgaga
    33721 taatctccca accaagtttt ttgagttctt gggcaaattc aacaatgccc gctttgtctg
    33781 agacgctgat taagacgcgt ttagtcatta tattctcctt tttaatcatt agttaaacac
    33841 caattaaatg cagtaacagt aaaacaagat aagcaaaacc aaggctaagc atacctaaga
    33901 tattgatcca ttttctagtc tgtgatttga acactcttat aaaaatttga taaatcagta
    33961 agcctacaca gacacctagc gtatttaaag tcaaatccgt tatatctgtt atacctattg
    34021 ctaaaatata ctgtaagcac tcaaacaata aactaatcaa gaaacctgtc ccgactattc
    34081 ttaaactaga taaattagtt tttatcaaag ggaaacaaac acctaatgga ataaaggaaa
    34141 tcagattaaa taacatttca gcaaaaacaa tttttccatc gactattagt ggttctgaaa
    34201 atggaatcca attgatatac cttggagcta agaaaaatgc tataaattca ggatttgttt
    34261 caaacttaaa taagattccc caagttaata acatcagata gacataaaat acatatcgag
    34321 ttgttttttt agattctaac attacaaata cctccgtttg aagccgtctt caacaaacac
    34381 tgactccaat ttaaaatcaa agatatcata tgaatcatca aaaagtcaat ctgtaaatag
    34441 agccttcact acttccggat acaacctgta ctctgcttca tggatgcgag cttcaaatct
    34501 gtcaatggta tcatcagcta gtcgtggcac acgaacctgt ttgatgacct ggcctgtatc
    34561 cacacccgaa tccacccagt gaatggtcac accagactga cccacgccag cattccaagc
    34621 atcctcaatc ccatgagctc ctggaaattc tggcaagtag gctggatgaa tgttgacaat
    34681 ccgaccttca taagccgaca ataaggttgg tccaactatt ttcatgtagc ctgctaggca
    34741 aaccaagtca atctggtgtt cttccaagag ttcgacaagg gctgcttcgt agtctgcctt
    34801 gctctcaaac tccttgagtt caaaagcata ggacagaacg ccgagctgct ttgcacgctc
    34861 aagcacatag gcatcacgat ggtctgaaaa gacaaactcc actggaaatt cttcggcaat
    34921 cacctgaaaa tttgagccat taccagaggc aaaaaccgct atttttttca tttgataatg
    34981 acactttcgt tttctttctt gacgatgcga ccaatttcat agactgcttc atccaacaat
    35041 tcttttacac gctctacatt ttcagggctg accgccaaca tgagtcccac acccatattg
    35101 aagatttcaa acatttcttc gtgtttaatc tgaccgtatt tttcaagggc tttgaaaatt
    35161 ggaagcactg gaactttgct ttcatcaatt tcagcagcta ggtcatctgc aaacatacga
    35221 gggacatttt cgataaagcc accacctgtg atgtgggcaa tgccgttgac caactcttct
    35281 ttgatgagcg gcaagacagc cttgacatag atacgagtcg gctcaagtag aacttcctta
    35341 agtttcttgc cttccaattc tggtaggact tcctcacctg tgtaatccgc aaagacacga
    35401 cgaaccaaag agtaaccatt tgagtgaatc ccacttgaaa caagtccgag aagaacatct
    35461 ccctctacca cctttgaacc gtcaatgatt tgagattttt cagccacacc gaccgcaaaa
    35521 ccagccaagt catagtcgtc ttcgccgtac atgcccggca tttcagccgt ttccccaccg
    35581 atgagggcag caccagcctg cacacaacct tctgccacac cagcaaccac ttgttctagc
    35641 ttagctggtt cattcttccc tgtcgctacg tagtcgagaa aatagagggg ttccgcacct
    35701 gcagcaatga tgtcgttgac acacatggcc acacagtcct gcccgatggt atcgtgcttg
    35761 tcgtacttga tagccaacat gagcttggtt ccgacaccgt cagtccctga aatcaagacg
    35821 ggttctttaa ccccagtctt ggaaaggtca aacataccac caaagccacc aagagctccc
    35881 atgacacctg cacgctccgt acgggccacg tgctttttaa tccgttcaac aacttcataa
    35941 cccgcttcaa catccacacc cgactgggca tatgcatttt tatttgtcat ttgttttttc
    36001 cttttcttta atggagaatc tgtcgcctac ttgtaaaaac tggtcttttc ttccaaactt
    36061 ctacgatagt cttcttcgta gtcatagaga ggcgttgggt agtcaccgtc aaagtaagcg
    36121 acacagagac caccgttcgg cgcatctgtt tcgataccaa tcgactcaat caagccatca
    36181 attgaaagat aagtcatact gtccgcacca atgatttggc gagtttcttc gaccgtatga
    36241 ttggctgcaa tcagctcctg acgggtctgg atatcaatcc cgtagaaaca tggatacgct
    36301 agtgcaggac ttccaatggc aacgtgaacc tcagtcgcac ccgcttcttt caagagctga
    36361 acgatacgac gagaggttgt tccacgtaca atggaatcat ccaccatgac cacacgtttg
    36421 cctttgacaa cacccgaaac agcagacagt ttcatccgca ctccttgctc ccgcaattct
    36481 tgagtcggtt ggataaaagt tcgctgggtg tattggtttt tgatcagacc catttcattt
    36541 ggtaagcctg attcttccgc aaatcccata gccgcgctta gggaagaatt gggcacacca
    36601 actacaatat ctgcctcatg cttaaattct cgcgccaatt gcgctcccat tctcttacgt
    36661 gccgtatgga cattgacacc gtggatatta gaatcagggc gagcaaagta gatatactcc
    36721 atagaacaaa tcgccaactg ggtatcatct gtatagctgt catactgaat gccctcgtca
    36781 tcaatgatca caatctcacc tggcttcaaa tcacgaatcc actcggcacc aataacctca
    36841 aaagcacagg tttcagaaga tacaacaact gctccattag ccattttccc gatagaaagc
    36901 ggacggaaac cattggggtc aagagccgca atcaacttgt cctcaaacag caagatatag
    36961 gcaaaaccac ctttgacaag gctgagcgct tccttgattt tgcccatcag gctaggatta
    37021 tgactgcgac gaatgagatg agccaagatt tccgaatccg aagtcgcact gaaaattgct
    37081 cctctatctt ccaattcttt cttgagagag gctgcattgg tcagattccc attatgagcc
    37141 aagccaaact gcatatcgtg aaaacggaag aggaagggct ggatgttatc tacagaagct
    37201 tcgccagcag tcgcataacg cacatgccca atcgcaccag tccctgtcaa tttatccaaa
    37261 ttagcaggat ttctgaagac ttctgataaa agtcccatgt cacgatggcg ctttagtttt
    37321 ccttggtcat tggagaggat tcctgccccc tcttgaccac ggtgctgaag actgtggagt
    37381 ccaaaatagg tcaacttagc agcatctgga tgtccccaaa taccgaaaac accacattct
    37441 tcattaagag attttacttc gtatgtcatt ttttatacct aattttcatt tgtaatcatc
    37501 aagagctaga tttacatgac ttttacatta ctgatactat ctattagaaa atctgtaagt
    37561 cttattttcc agtgaaatgt ttaaccgctg acgcgaacag gtgctggtct ttattgcctg
    37621 ggatattttg gaaaagaccg tcctcataac gttctgagtg gcccatctta ccgatgattt
    37681 gaccattctt gctggtaatt ccttcgatgg catggacaga accattcgga ttgtacttag
    37741 aatccatact tggtttaccg ttaaagtcaa cgtattggct gaaaatttgt ccattgtcac
    37801 ggagctctgc aaattcctca gccgtcacga caaacttccc ttcaccgtgc gaaacaggaa
    37861 tagcgtggat atcgcccact tgcacaccag ccaaccatgg tgagttggta ttggcaatgc
    37921 gagtttccac catcttggcc acgtgttggt tggcatcatt gtagaagagg gttgggctag
    37981 tactgttagc aacttcaaag tttccgtagg gtaggagacc cgatttgact aaggcttgga
    38041 atccattaca aataccgata atcaaaccac cacgggcgat aaagctatca atagccacac
    38101 gcactttttc attaagcagg atattgacga taaacttagc tgaaccatct ggttcatccg
    38161 cagccgagaa tccaccagca aagaagagaa tattagtctt gtcgatattg tcaaccatag
    38221 tttcaactga cttgacaata gcttcttcat tcaaggtcac gaatggcacc aaattgacct
    38281 ctgcaccttc tttttcgaag gccttagctg aatcatattc tgagttggtt cctggaaaga
    38341 ctgggatgta aaccacaggt ttttcaacct tttctttggc tttaatcaca acatctgatg
    38401 ccacagctgg tacttcttct agttctttcg cttgggtaaa ttctgttggg taaacttctt
    38461 ccaatgtccc ttgaaatgca ctgtcaagct tgtgtccatc tagcttcaca ccgttgacag
    38521 tcagtgtaaa gtctgctttc gtttgtccaa ccttctctac tccagcaatt tcttcaggag
    38581 atgtgaagac aaagccgcct aattgagctg tcaaagctgt ttcaagttca ggcaaggtca
    38641 cctctgcacc aatatagttt ccaaaggtag caagagccaa actttcaact acaccaccgt
    38701 atttgacagc tgatgcagat gtcactttat ggtcagcttg gatggcttca aactgagcaa
    38761 aatttttctt aatcaagtca aaatcaatct ctgcagagag ggcttgacct gggatgtagt
    38821 agatattttc cccaacagct ttaaattctg gagagagcac cttacggcta tctgccgtcg
    38881 tcaccccaaa ggcaaccaag gttggcggaa cggtcaattc ttcaaaggta ccagacatgg
    38941 agtccttacc accgatagat ggcaagccaa gctgaatttg tgcttcaata gaacctagaa
    39001 gagcagctac tggctgaccg aaacgctctg cttgtttatc catacgctcg aaatactctt
    39061 ggtaagagaa acgagccttg gaccagttgg caccagcagc caccaaacga gcagttgctt
    39121 cgataaccgc ataagcagca ccgtggtatg gagaccattc agctacatat gggttgaaac
    39181 cttgagcaat gaccgacgca gtatgagtca caccgtgttg aactggcaat ttctgcacag
    39241 atgcctcagt tggtgtgagt tggtaacgac caccaagtgg gtgattaacc gttgagcgtc
    39301 caacagagca gtcaaagata gtctgtaatc ctttttgact tgcatggttg aggtcagata
    39361 gaaccgtaag ggtatctgat tccagtgttt cagcagatgt ttgacgctct tctgggagtt
    39421 tgacatcctt gtccacaact ttggcatcga caaccacgcg cacaccattg gtgtcaagga
    39481 aacgacgctc caagtcaacg attgtctcac cattccagtg catgacaaga tttggttttt
    39541 cagttactat cgccaccaca acagcatcaa tattttcttt gttacattcg gcaacgaagg
    39601 catccacatc ttcaggacga accacgaccg ccatccgttc ttgtgattca gagatggcaa
    39661 tttctgtacc attcaagccc tggtatttaa gaggcacctt gttgaggtcg atttcaagac
    39721 cgtctgccaa ttcaccgata gccacacaga cgccgcctgc cccaaagtca ttggacttct
    39781 tgatcagacg agtgacattg ccattacgga agaggcgctg aatcttgcgt tcttcgatgg
    39841 catttccttt ttgaacctca gcaccagcag tctctacaga ctcaactgtt tgaaccttag
    39901 aagagcccgt cgcaccaccg acaccatcac gacctgtttt gcctccgaga aggatgatca
    39961 catcacctgc ttcaggtttt tcacggacaa cattgccctt gggagccgca ccaacaacgg
    40021 caccaagttc catacgttta gctacaaagc ctgggtggaa gtattcacga acgtaggttg
    40081 tggcaagccc aatctggtta ccatatgaag aataaccatg agctgctgtt ttagaaatga
    40141 cttgttgtgg caatttccca gcacgagttt ccgaaatcgg tgctgtaata tcaccagcac
    40201 ctgaaatacg catggcttgg taaacatagg aacggcctga caacggatca cgaatagctc
    40261 caccgataca ggtagccgct ccaccaaatg gctcaatttc tgttggatgg ttgtgggttt
    40321 catttttaaa catgaggagc caaggttcct tgacaccatc aacatccact tcaatttcaa
    40381 ctgagcaggc attgatttcg tcagagactt ccatatcatc caatcgtccg ttagcacgct
    40441 cataacgacc gaaaatagtc gccatatcca tcaaggtttg tggtttttca gaccgaccta
    40501 actcctcgcg catggcaata tacttgtcat aggttgactg caattgcttt tgaaatttag
    40561 aagctgaaaa gtcgatgtgt ttcaactctg tctcaaaagt cgtatgacgg cagtggtcag
    40621 accagtaagt gtccaaaacc ttgagttcag tctcagttgg cacgcgcccg attgacttaa
    40681 agtagtcttg gataaagagc aaatcatcca cttccatggc catcccttgc tcggccttgt
    40741 agcgagcaaa gtcttctgct gtatagcttt caaagaaagt caattttgga atggtcttgt
    40801 ctgactctga aaactcctgc ttggcaatcc ctgtcgtgat atccttgaaa cgagaatcaa
    40861 ctggattgag caggtagttt ttgacagctt ccaactcagt cgcatcaata tctttattca
    40921 ccaagtaaag ttgggctgtg ttgactgtca cgtcactcga acttcccaac aaaagcaagg
    40981 cttcctgtga cgaagctgca cgctggtcaa actgccctgg cagactttca atggcaaaga
    41041 aagcatagtt agcaagatcc gcctgcacag atacttcatc taaaacatgg tcggttccct
    41101 gctcagagaa aatgtgcttc tctgcaggtg caaacaagtc ctcagccaag tcaaatacat
    41161 catatacttg cacaatacga atacttttca agcttgacag tcccacgttg tgctggagct
    41221 ctctaaccaa actctctgac ttgacctgaa aatcagcctt tttttcaaca aaaatacgtt
    41281 tatccatcaa ttcttattcc tttatttcag ctcttgcaat attcccaaac agccttgagg
    41341 ttgttatttt aaaccctgca acttttccca aacaatctca taaacgtcgg ttagttctcc
    41401 caatcctcta cggaaaacat ccttatccat gtggttgcca tcagcgtccc acaagcggca
    41461 gttatctggt gaaaattcgt ctgccaagat aatcttgcca tccttgtcaa aaccgaactc
    41521 tagcttaaag tcaatcaatt taagcccaat ctcagcaaac cagactttca atagttcatt
    41581 gatacgacgc gtttcttcct tcaagtaggc aatctgctgg tcacccgcaa tctgtaggaa
    41641 tttcacatgc tcatcattga taaatggatc atccaaatca tcatttttgt agtaaaattc
    41701 gacaatcgga gtctccaagg cgattccctc atccacacca aaacgttttg aaaaggaacc
    41761 agcagtatag ttgcggagca cgacttccaa aggaataatc ttaacctttt tattgagttg
    41821 ttccgtgtct gaaagtttct ccacaaagtg agtcgccaca ccagccgcat ttaatttctc
    41881 aaaaataaaa gatgaaatct gattattcaa gactccctta cctgcaatct gctccttctt
    41941 gacaccgttg aaagcagtcg cctggtcctt gtaagttgaa ataataagat tttcatcctc
    42001 agttgtatag atatctttag cttttcccga atagatcaat tgttttgaca ttttaaagtt
    42061 cgcctttcgt attacttgag cacattttac cacaaaaaac caaaaaacac aagaattcaa
    42121 ccgaataaat agcagatgtt tttcaaaaat tgtaaagaaa aaactgcaag aagaatcttt
    42181 ctcacagttt aaaaattatt taactctaaa aacacgaaca ttactctttg ttcaaaaatt
    42241 gatccaaata ataacgtagg taacttttct tgcccgtaat catctgtaga cggccttcca
    42301 ccccgtacct aagtttttca gcctgctccg aagttagatt agtctccgcc tcgattttaa
    42361 agaaattccc tttctcagtc ttagtagctg tcgcatcaat acttgtaata gtagaatcta
    42421 gaaaaagttg attcccggca tcatgagtcg tagtatagcg aacagaatca ccgaccttga
    42481 ttcttgctac atcttttgaa cttagatagg ctgtgagttt ggctttccct tctctttcca
    42541 aagatggata aagttgggct agtagggcac cttctgcaac catgctagaa tcactggtct
    42601 caggattaag atgaagcacc ccatcctcac ttgccgtaat tttccccttg tctaaaagat
    42661 ttccctgtac cttcttacct gactctgcct ccaagatttt ctgggctaga agggtcaatt
    42721 cctgaccaac ctttgccaag tgttgggatt taagggattc caattgactg cttaaccctg
    42781 acgcataggc ttgctgggta cctgaacctg catactggac acggtaagta gcaagactag
    42841 attctaactg agaaatctgt gcttcaacct gtgcaactgc ctgaacctta gtttggggat
    42901 tttcctcgcc ctgagacttg taggactggt aaagagagta ggctagattc tgactggcca
    42961 aggaagcacc tgtttccata gctgacttag ctgtctggta atcgcgaatt ttagcctctg
    43021 tttgattgat gaggttgccg atttcggctt gggtttggct agctgctgca ttctgggacg
    43081 cgatggtctc attttgttgc gatgtactag ccctaagact gcctgcttga ctgatgtagt
    43141 cgcgaaaggt ggcttggtag ccaaacttat cctcctctgg aaagtggttc tccccttctt
    43201 gcaggctctt ttgcagatac tccaattgct ttttttgatc ctttagcatg tccaactgac
    43261 tggcatagga ctccgcttgg acaccctctg ccccttcttg gtattgaacc aaaagatcct
    43321 ccttcttaac cagcttattt tcttccaaat gattgacaag aatacgattg ttgctagttg
    43381 actggatatt tgcaaggata cgactaggtt cgacagtagc tctagtggac aagctcatct
    43441 ccttttctgc aacagttgca aagccaagta aaaacacgag cagaagggcc atgggtacaa
    43501 tcacactact ggaaaaatta tggtaacgac gattataaaa ctccgcactt tctaaaaatt
    43561 ctggtttcat cctctcctct ttctagctat tgaccaaatg ggcgtaaaag ccaccctgtg
    43621 caagcaaatc agcatgcttt ccttcttcga caatcttgcc ctgatccaag acaaccacct
    43681 tctctgtccg ctcagcaata gtcaagcggt gagcaatgaa aatcaaggtc ttgtccaaag
    43741 ccatgagatt atcgacaatc cgcttctctg tcaaaatatc caaactgcta gtcgcctcat
    43801 ccaaaatcaa gaccggcgca tctgtcaaga gagcacgcgc caaagcgatt ctctgacgtt
    43861 gaccacctga aatccctgcc ccatccgaag tcaattctgt ctgataattc agtggcatgc
    43921 gctcgatatc ctctcgaatc tctgccaatt cgaccgcccg taagatatct tcctgtgtcg
    43981 tcccctcctt ggctcccaaa agaagattct ccaaaatcgt tccgttaaag acatagggct
    44041 gttgaggcag atagtttatg tactggcgca gggctttttt atcaatctga ttgagattga
    44101 cactacccag actaatctcc ccttgacttg ggtcgtaaaa attaaccatc atcttggcca
    44161 aagtcgtctt acctgaccct gaaatcccca caaaagccac cttagaccct tggggaacgg
    44221 ttaaattgat atccgacaag acgtctcgac catagccata cttgtaatga acctgcttga
    44281 aggtcatatc tcccttcatc aagctcaaat cctcaactgt tttcttctcc tcaaactcag
    44341 aagctactag atacacttca tttagacggt tattggcaac ctgcgctgtc tgaagcttgg
    44401 tttgcagatt gatgatattt tccaaaggat tggtaaagta aaccagcaag gtattatagg
    44461 taatcaactg ccccaaactc atcttgccat ccatgaccag aacagccccc atccagagaa
    44521 tgccgacatt aagcaagaga tgggcaacct ttttcagagc cttttgctga ctctctgctc
    44581 gactataggt aaaggatttc ttcagataat ccacaaattc cttgtcaatt ttttggtaac
    44641 gctgactttc actggtcaag gacttgatag tctcaatacc gttgatgtcc tcaatgatag
    44701 aagaagacag aaccgcattg gcttccatgg tatcccgatt catcttttca aacggcttca
    44761 taaaggcaaa gataatcact gtgtagatag gaagcgccaa taaagtcatg aaaaagagat
    44821 tggtattttg tgaaaataga acaagggaaa taatgacaac cgttgacaca tctaggaaaa
    44881 tcgaaaggat ggtcgaagcc agcgcatcga tgatactgtt agcatctgta aaacgagaca
    44941 cgatttcccc tgtcctgcgt gtcgcaaaga aggacatagg gaggtgaaaa acatgcttga
    45001 tataggacaa aatcacgtca atcgacaagc gttgccccaa aacaagcaag agatactcct
    45061 gagcgtaaga caagatttgc tggaggatgt agacgatgac tagcccaata gaaataatcc
    45121 ctagtgtcga acgcatctga tctggcacat aggtatcaat gatagactgc agataataag
    45181 aacccacaat gttaatcacg gttaccaaga gtgttgccaa aacgatattg gcaatcaagc
    45241 cacgctgctt cactaatata gggataaaag agaacagacc atttttttgt tccttatgag
    45301 gcttgtagtc tggactaggt gccataaaaa gagtcactcc tgtccattct tccgcaaaac
    45361 gctcacgtgg cagtttggtc aacttcaccc cgggatctgg atcggcaata tgaatgctat
    45421 ccttatcctg cccagtcacc acatagtagt ggagcaattt cccttcctta agcacatggg
    45481 caacaaaagg aaaagtcaaa tccggcaagt caaaaagcgt catatccgcc ttaatggctc
    45541 gcgtctcaaa accaatctcc tctgccacct tgaccaagcc caaagccgtc gttccatcca
    45601 tggtcgtctt agccaattct cgcaagtgag ccaaaaaata ataactacca tagtagccaa
    45661 aaaccatggc taatgaagct acaccgcagt ccatctgatc cacttgcgga cgatagtgac
    45721 gtttcccaaa tttcatattc atctcctttt ccctaatact caatgaaaat caaagagcaa
    45781 actaggaaac tagccgcagg ctgctcaaaa cactgttttg aggttgtaga taggactgac
    45841 gaagtcagtc acatatatac ggcaaggcga cgttgacgtg gtttgaattt gattttcgaa
    45901 gaatataaac tcatctgata acaactatct taccccaatc actaaacaaa aactggactt
    45961 ccttcccaaa tgagcctatc tccctcccaa ctgcactttt tggataaaaa aataggcaga
    46021 acaagagtcc tgcccactaa aaatatgcta ttgaaaggaa aatgattttt tactgacacc
    46081 ctaggcaagc ttgaaacaaa taaatcattg atagtaacac ttacgacatc ctatttatta
    46141 cttcaatttc taatgtctct gctatttcta agctacctat ggtatgatct atccctagtc
    46201 agaatagata acaccgttct aaattacgat tcatagttac tccttttttg actcgttact
    46261 ataagactcc tctttacatg cgcaaaataa ttttgattca gattcatcat ttatagtttt
    46321 gattattttt taacagattt ttctgttttc ttctccgaag actttaaaaa tttttttcta
    46381 attaaatcat ccatataagg accaaatata ccaactacta aaccaataat aaaactttta
    46441 aaatccataa ttaccaccaa catgtcgctt cataggccac acctccaagt atagctcctc
    46501 ccgcagcacc agttgctgca ccttgccatg ttcttgtttt aattcctagc tgaagacctc
    46561 gtgctactcc tcctccaaca cctgctttgg caaaatctcc ccaattgcat ccgccacctt
    46621 caactcaagc aagcatctca gtatccataa tttcaaattg tgacatcttt tttgtattca
    46681 taacgaatac ctctttttta tttttaatat ttgtcttgtt acaaacttga caagtttagt
    46741 ataacagtat ctattaattt ttttcatcca aatcttgaat tggcatcgaa acgtcttgaa
    46801 ttagcttttt tgtttcaaaa tcatctctat ttttaaaaaa gatgttttct aatcactttt
    46861 ttactattag acttcctgca aaactagaat cctagttcat gattgataat accagcaatc
    46921 aaattcattc gtaatccgaa gcgtttacga tgatttcgat aggttgttga aaacatttta
    46981 aacgttttta ctttggcaaa gatattctca accttgcttc tctccttaga tagcgcatga
    47041 ttacaggctt tatcttcaac tgttagcggc ttgagtttgc tggatttacg tggaagtttg
    47101 tgcttgagga tatatcttca tgagcccttg ataaccactg tcagccaaga ttttaccagc
    47161 ttgtccgata tttctcattt ctaaaaacca tctacttccg ttgacttgga actccgattg
    47221 ctattttcct tgaatgattt taaccacatc tcctacactt tggagttggt caatttcctc
    47281 atcgctgatt tcgatactaa attcatcctc cagcgtcaag ataaactcca tcaaatcaac
    47341 tgagtcagca tccaagtcgt ctttcagact caaggattct gtcacgacaa agtcctctcc
    47401 ctgtcgctct tggataatgg tcacaatact gtcaaaaatt tctttttctt tcatctcttt
    47461 tattctcctg aaaattcacg cgcagtctgg gcaactactt ctgtttctag catggtacga
    47521 atctggcgaa tcgtactata aacagccttg gcatcgcttg agccatgagt cttgacaaca
    47581 ggtgccttga caccaaacaa gaccgctcca ccaacatctg aataattgag ctgttttttc
    47641 aaacctctga ggctgtcctt gagaaggagg gcacctagtt tcgctcgaag accaccacct
    47701 gtaatagctg tcttgagcaa gcccatgatt cccatagctg tcccttcgat ggatttgagc
    47761 acagcgtttc ccgtgaaacc atctgccaca acaacatctg caacaccatt catcaaatca
    47821 cgcgcttcca cgtttccgat aaagttcaaa ctttcatcag ccgccagtaa ttcataagtt
    47881 tccttacgaa gcgggtcgcc cttgctactc tctgttccgt tgttgagcaa accaacacgt
    47941 ggttgcgcaa tgccacgaac attcttggca tagaaagaac ctaggacagc gtattgatgg
    48001 aggtgctggg ctgtattttc tgcattagca ccgaggtcaa gcatgtcaaa acctttccca
    48061 tctacagtcg gcaatgttga cataagtcca ggacggtcga tattcttgat acgacccacg
    48121 atgaagaatc cagcagccaa caaagcacct gtattcccag ccgaaaggac agcgtctgct
    48181 tcaccatctt tgacagcctt ggctgccaat accatactgg catttttctt attccgaata
    48241 gctctcgtag gttcatcatc cgaatcaatc ttctcatccg tatggataat gctgacgcgc
    48301 tctgtcgctg tcagatattg cttgatttta gcttcatctc cgtagagttg aacctcgata
    48361 tctgaaaagt cagatagggc ttgattgaca ccctcaacga tggcctgagg tgcgtaatcg
    48421 ccccccatgg catctactgc gatttttttc atttcttttc ctcttttagt aattgtcccc
    48481 agtctgctag ggaatcaata aatttctttg attttaggtg aatcccaacg tactcttcat
    48541 atagttgatc cataaattgg cgtagctctt gcttgattcc aggcttgagc gaaatggtct
    48601 ccaaagtctc aaaatcaata gcttgaaatt gattgagcag ataggggata ttgggattga
    48661 gatggcaacg tctctcatcc tcatgataat gctctggaca gagacaggct ccatatttga
    48721 aagaaaagtc aaaagcctga ccaacccgat ggcagaagac acactcatta aaattgaggc
    48781 tgattccaaa tcgagtcaaa atttgaattt caaaaatatt ggtcaaaacc tgataatcca
    48841 agcctgcttc catcaactcc aaagtctttt gcaaaaaagc aaacaaggga gcatcctgct
    48901 gattgtcctg caaactagca tctgcaagag ctgccacata ggtcgcatag gccatgacaa
    48961 agaggtcact attaatcttg ggaaaagtca tgacctcatg atagtcttcg atgtaactga
    49021 gtccgtcatc attgattcgc aagagaaatc gtgccagcac caagggctga ataacaggcg
    49081 ccagcttaga ctgaccagcg tgtttgacaa aaaacatgca tttgccaacc tgctctgtaa
    49141 aaattttgac aagcttgtca tcctcacgaa aattgcgatt gtaaagcacc aagccttgac
    49201 tcgtgataga ctgaatcatg cttctctcat atactcctca agtcgtttca tggcttcttt
    49261 gatagtctcc atgctggctg cataagatag gcggacgtag ccttccccgt aacgtccaaa
    49321 ggctgcacca gggataaagg caacggcctt cttctgagca aaatccttca gaaaagcaaa
    49381 ggagtcttga ttgtagcccg ctggaatttt agcaaaaata tagaaggcac cgtctggttt
    49441 gataatctca aaaccaagag cagtcatttt ttcgatgata tagtcccgac gctggatata
    49501 ttccttcttc atgggctccg catcattttt accagccgtc aaggcttcta ccgcagcatg
    49561 ttgcgccatg gtatttgcgg cagtgaccaa gtattggtga ctcttgatta actgggatgt
    49621 gaaggccgca ggagcgaaaa tcagccccaa acgccaacct gtcatggcat gcgatttaga
    49681 caaaccattg ataataatag cctggtctct caacatcgtt cctagagaca catgggcttc
    49741 gcctgtgtag gtcaattctg agtaaacctc atcacagaca acaaaaattt cgtacttgcg
    49801 taaaacagct gccaaggcct ctaactgctc tcgactgtag gtaattcctg tcggattggc
    49861 tggatagttg agaataaccg ccttgagctt atcaccctgc tccaaaatgg ccttctccaa
    49921 catctcagga gtcaagacaa aaccattttc agtcgtatca atctcaacaa tttctgcccc
    49981 aactaagtta acaatcggtt catagcctgg ataagcagga gctggcaaaa gtaccttgtc
    50041 tccctcttcc aaaatagccg tcaaagtcgc agataaagcc tctgtcgccc caattgtaac
    50101 caagatttca ttttcaggag catagtccag ttggtacttt tccttaacaa agtcactagc
    50161 tgcctgacgt agagtcagca gaccactcat ccctgtatag taggattggt tctgatcaat
    50221 cgctcgcttg gccgcctcct tgacatggtc tggcgttgta aaatcaggtt cccccaaggt
    50281 caaacgcaag accccaggaa tctccgaaat agcctggtca aactgacgaa tcaacgaaac
    50341 ttgaatttta tctaactgtt tattaaagcg cttagttaag tccatagata cctcctactt
    50401 tcaaaacgta tctctattat actacaaaag ccccccgacc gcaaaaatac attagaggat
    50461 agctttccac tttctatttt acttttcctg tttataggtc tataatggta atagatttta
    50521 tttggaggtt tttatgtcat ttctatcaaa aaatggagca ggtatcttgg cctgccttct
    50581 catttctatc gtatcttggt acttaggagg attcttccct gtgattggcg cgcccgtttt
    50641 tgccattttc ataggcatgc tcctacatcc ctttctctcg tcctataaac aactggatgc
    50701 tggtttgacc tttagttcca agaagttgct ccaatatgcc gttgtcttgc ttggttttgg
    50761 tctcaatatc tcgcaggtct tcgcagttgg ccaatcttca ctccctgtca tcctgtccac
    50821 tatctcaata gctctgatta ttgcctacct cttccagcgt ttctttgccc tggatacaaa
    50881 actggctacc ttggttggag taggttcttc tatctgtggg ggttctgcca ttgcagcgac
    50941 agcgcccgtt attgatgcta aggaaaagga agtagcccaa gccatttccg ttatcttttt
    51001 cttcaatgtc ttggctgcgc tcatctttcc aaccctcggc acctggcttc atctatccaa
    51061 tgaaggcttc gccctctttg cagggactgc ggtcaacgac acttcctctg taacggctgc
    51121 cgccagcgct tgggacagtc tttaccaaag caataccctc gagtctgcaa ccattgttaa
    51181 actcacacgt actttggcca ttatccctat cacgctcttt ctatcctact ggcaaagtcg
    51241 ccaacaagaa aacaagcaaa gcctgcaact gaaaaaagtc ttcccacttt ttatccttta
    51301 ctttatcctt gcctctctcc tcactacact actcacctct ctaggtgtgt ccagtagttt
    51361 ctttactcct ctcaaagaac tctctaaatt ccttattgtc atggccatga gtgctatcgg
    51421 tctcaaaacc aatctggtcg ctatggtcaa atccagtgga aaatccattc ttcttggagc
    51481 catctgctgg attgccatca tcctcaccac tcttggtatg cagaccctta tcggcatttt
    51541 ctaacactct tcgaaaatct cttcaaacca cgtcaacgtc gccttgccgt atatatgtta
    51601 ctgacttcgt cagttctatc tgcaacctca aaacggtgtt ttgagcagcc cgcggctagt
    51661 ttcctagttt gctctttgat tttcattgag tataacacaa aaggtagccc atcagctacc
    51721 tttttcttat gcttcctcaa tcaagcgagt atgttctctc ttgatacagc gattcatcac
    51781 gatatcatca catccaccat cacgcaaaat ctctttcgct tctaaacttt caagtcctag
    51841 ctgtgcccaa aaaatcttgg catcagcttt gagaaaatca cgcgccacat cgggcagaaa
    51901 ttcactgcga cgataaacat tgacaatatc tacaggaaaa ggaatttcag cgaggctagc
    51961 ataagccttt tcacccaaga tttcgccacc tgccgccttg ggattgactg ggatgatttt
    52021 atagccccga gcctgcattt cctttgttac tcgattgctg gttgtttctt cacggtcaga
    52081 caaacccacc acagcaaggg ttttactcgt tgcgagatac tgacgaatca cgccatcact
    52141 tggattgata aattcttgac tcatagaaat cctccttttt catcagtata gcacattttg
    52201 aaaaggtttg cagaattata ctacaaaaaa ggaggactag cccccttttt atttagcctc
    52261 gtaccaggtt gccccttcat tctcatctgc gataagagga acactgagtt gaatggcttc
    52321 ttccatggtt tgtttcacca attttttcat ctctaccaat tcagatttag gcacttcaag
    52381 gacgatttca tcgtgcactt gtaacagcat cttagtctga taaccacctg caaccaaggc
    52441 tttatccagc tgaatcatgg caatcttgag aatatctgct gccgaaccct ggataggtga
    52501 gttgatagca gttcgttccg caaaaccacg aatattgaag ttgcgcgaat tgatatctgg
    52561 caactcacgg cgacgcttaa agagggtctc tacatagccc ttatcacgcg cctcccgcac
    52621 cacttcatcc atgtagtttt taatacctgg aaaacgttca aagtaggtat caatgtaggc
    52681 tttggcttcc ttacgactaa ttcccaaatt attagacaag ccaaagtctg aaatcccata
    52741 aaccactcca aagttaactg ccttggcatt gcgacggtcg tttgcagtca catcatcagg
    52801 acgctcaatg ccaaagaccc gcatggctgt cgaagtatgg atatctgccc cctcttggaa
    52861 ggccttaatc aagtgctcat ccttagaaat atgcgccaaa acgcgcaatt caatctgtga
    52921 atagtcagag ctgagtagca cactatcctc ccactctggc acaaaagcct tccgaatcaa
    52981 gcgcccctgt tccaatcggg caggaatatt ttgcaagttt ggatccacac tagacaaacg
    53041 cccggtctgg gtcaaatcct gcacatagcg agtatgaatc tttccatcag ccaaaatcca
    53101 gtcctgcaag ccaattacat aagtagattg aatcttagca atttgacggt aatccaggat
    53161 tttcttaaca atcggagcaa taggagcgag acgctccaaa acatccactg ctgtcgaata
    53221 acctgtcttg gttttcttag tgtattctag aggaagtccc aatttctcaa agagaagcac
    53281 gcccaactgc ttaggcgagt tgacattaaa ctcctcacca gccagctcgt aaatctcttg
    53341 agtcagtttt tcaatgacaa gctcattttc agcctgcatc tcaagcaagg tctctttctt
    53401 gaccataatc ccagcaattt ccatcttggc aaggacaaaa gccagaggtt gctccatatc
    53461 ataaagaagc tctaattgcc cattttcgct gagtttttca agtaaaatag gctctgtttc
    53521 taccaaaaca gcaagtttac aagctaagtg ttccaagaat ttctcacgtt caggaatggc
    53581 ctttttaaca cccttaccgt agaaagtttc atcatcaacc aagtaagtct gaccataaag
    53641 actagcgatg gtcgcaattt cattgtcctc cacagtcgaa aggaggtatt tagccaaacg
    53701 gatgtcaaaa gcaggcgcct gcaaatccac accaaaacgt tgcaaaagaa ctttaacctt
    53761 cttaaagtca taaactctca gagatgtttt ttctaagaaa tccttgaaaa tcgggtcttg
    53821 caacagctca agcttgtctg tggcatagag cttatcccca caagaccagg caaatccaac
    53881 caaattatcc gtatggtaat tctcaccaaa aagctcaaag tggaagatag actcttcact
    53941 cagcatatct tgactgattt ggtcaacaat agtaaaatcc aaactctcag acacatcagc
    54001 tgacgacaca tttaaagcct gctttagctg tttgaagccc atctcatcgt agaatttccc
    54061 aagattttca acatctggac cactatagac caagtcctct aaaccaatcg caatcggtgc
    54121 cttggtatca atggtcgcta gtgttttaga caaaaaggcc tgttccttgt cattgatgag
    54181 attttccttc atcttagaag tcttcattcc atcaatattt tcataaatcc cctcaagcga
    54241 accatgctcc agcaagagct taatacccgt cttttcaccg actttggtca ccccagggat
    54301 attatccgac ttatcaccca tgagcgcctt gagatcgata aactgagctg gtgtgaggcc
    54361 catttcttcc atgaggtaat ctggcgtaaa ggcctcaaac tcagccacac ctttcttgga
    54421 aatttcaacc accgtatgct catccgtcag ctgaatcaaa tccttgtccc cactgacaat
    54481 ggtaatatca aaaccatcct gctctgctag cttatccagc gtcccaatga tgtcatccgc
    54541 ctcatactga gccagctcat agtgacgaat ccccatatga tccagcaact cacgaatgaa
    54601 aggaaattgc tcacgaaact catcaggagt cttggcccga ccacccttat agtccgcata
    54661 catctctgtc cggaaggtcg tctttcccgc atcaaaagcc accaaaatat gactcggctc
    54721 aacccgctcc aacaaatgac tcaacatcaa ctgaaaacca taaatcgcat tggtatgcaa
    54781 accagccgca ttcttaaaac ggtccaactg ctgatacagc gcaaaaaacg cccgaaaagc
    54841 tacagaagac ccatcaatca ataataattt tttcttatcc atacacccat tataaaggaa
    54901 agaatcaaaa aataccattg ggaagagcta gagcaagtat ttttcaaact ttttccgaat
    54961 aaatagatag agccagagaa tttagtaaac ctagatttaa aaatgtgcta taatatagta
    55021 tattgaatct ataatagtac accttgactg ctaaaatatt tctataaatt aatttgactt
    55081 tcctgataga gttattcaca tcttatttca actcactata gaaggaggaa taggaggatt
    55141 ctcagacatc cgggcatcag cccaactaat gatttgattg ctaagaaaat attcagcaat
    55201 ccagaaatca cttgtcaatt tattcgcgat atgctggact tgccagcaaa aaatgtgacc
    55261 attttggagg gaagcgatat tcacgtatta ctctccatgc cttactcggt gcaggatttt
    55321 tataccagta tagacgtctt ggcggagttg gataacggta ctcaagtaat tattgagatt
    55381 caagtccatc atcagaattt tttcatcaat cacttgtggg cttacctgtg cagtcaggtt
    55441 aatcaaaatc ttgaaaaaat tcgtcagcga gaaggtgata ctcactagat ctacaaacac
    55501 atcgctcctg tttacgtcat tgctatcgtg gatagtaatt atttctcaga tgacctggct
    55561 tttcatagct ttagtatgcg cgaagacaca acaggtgagg tattggcgat taccaacaat
    55621 ggacaggaaa accatctggt taagatggca ttcttggaat taaaaaatac agagaaacca
    55681 gcaaagacaa ggttcgcaag ccatggttgg agtttttcgg caacaagccc tttacccagc
    55741 aaccgcaacg agccattacc caagcaaatc aactgctgga ctacaagagc tggtccgagg
    55801 aggacaggaa aatgtttagt caactacata tgcgagaaga acaagtcttg ttagcacagg
    55861 actatgcctt ggaaactgct agggctgaag gccttgaaca aggactagag cgtgggaaag
    55921 ttgaaggaag ggcagaaagg aaactttttg ccttcctaga catagtacgc caaggtcttc
    55981 tgacttctga ggttgccagc cagcaattag gtatgtcagt atctgaattt gaggcactgt
    56041 tgtaaaatgg ctccataata tccatagggg atttacccac tatggatatt atggagccta
    56101 ttttgtgtaa aaaaaagtcc catatgacct ataatgaaaa gcgacaaaac aactcattag
    56161 aaagaatcat atggaacaat tacattttat cacaaaatta ctagacatta aagaccctaa
    56221 tgtccagatt ttaaacatca tcaataagga tacacacaag gaaatcatcg ccaaactgga
    56281 ctacgacgcc ccatcttgcc ctgagtgcgg aaaccaattg aagaaatatg actttcaaaa
    56341 accttctaaa attccttatc ttgaaacgac tggtatacct actagaattc tccttagaaa
    56401 gcgtcgattc aagtgctatc actgttcaaa aatgatggtc gctgaaactt ctgatgacgt
    56461 acagtcatat ttcttctctt tttattatat cacagtttta aatctagctt tactagattc
    56521 accgctacta tctatttatt cggaaaaaag acgaaaaaac ctgagaatca tctcaggctt
    56581 ggtcattaaa tttttttctc aatatcgaaa agtggagaaa gtggtcgttt ttcatgaata
    56641 cgtacgatag catcccctag gagatgagcg attgaaatct gctcaatctt atcaatcaaa
    56701 cgctcttctg gcagatagat ggtatccaaa acaaccaatt tcttaatagc tgatttttgg
    56761 atattgtccg tagcaggacc agaaagaact gggtgcgtac agcttgcata gacttcaaca
    56821 gcaccagctt ccgcaagagc atctgccgca tgacaaatcg ttccagcggt atcaatcata
    56881 tcatcaatca agatacaagt cttgccttca accttaccga tgatgttcat aacttcacta
    56941 gtattcatct tatcaacgct acgacgttta tcaataatag cgatagatgt tttcaaaaat
    57001 tctgccaact tacgagcacg agtcacccct ccatggtccg ggctgacaac cacatagtca
    57061 gaaccaacca taccacgacg ctcaaaataa tctgcaatca gaggagcacc catcaaatga
    57121 tccacaggaa tatcaaagaa tccttgaatt tgcgcagcat gcaagtcgat ggtcaataaa
    57181 cgatccactc cagctacttc aagcatattt gcgacaagtt ttgaagtgat tggctcacgc
    57241 gctctcgcct ttctatcctg acgtgcatac ccatagtaag gcatgacaac attaacagat
    57301 tctgcactcg cacgcttcaa agcatctacc ataatcaaaa tttcaagcag attgtcattt
    57361 acaggcgaac tagttgattg taagataaag acgtgtttcc cacggattga ttcttcaatg
    57421 ttgacctgaa tctctccatc tgaaaattgg cgaacacttg atttccccaa ctctatccca
    57481 atctcctgcg ccacacgttc tgccaattct ttattagaag aaagggcaaa cagctttaaa
    57541 tcagaaaaag acatgatttc ctccggtata tatgtataac ttgtgctttt cacaagattt
    57601 tccatctacc attgtagcgc tttttgcact atttttcaat caaaaataaa agaagggcac
    57661 catatttgta cccttgcatc attcttttga aaaatattct aggtcatcaa ctcattgtgt
    57721 ttctcaacaa agcaataagc atgataaaaa ccatagagag caatagccgt aaccactgga
    57781 atcgctaaag gcaactctgt ttccaactcc acaaaaggag agttaaacaa gaagtgagtt
    57841 cccaaggcta aacctagaaa aataagtccc tgtttcttgc caaccttctg tcctttatag
    57901 gctctgtaaa gcaagtaaac acctactaca gctagacctg aaaaagtcca gtgagaggca
    57961 attcctgaga tgatacgctc taaaattcgc gaaatagtaa agtcaaagcc ctctggcaaa
    58021 tccgtacgaa tataaccaat atcctcaatc atttggaatc ccaaaccgga agcaattcca
    58081 agtaaaaaca aagattttaa ttttcgcaca ggaatcaaag ccaaaacaaa aacaagtggc
    58141 aataatttca agggttcttc taccaaagga gccacaatag cactttcaaa ggcatttaaa
    58201 aatgtactat ctgggaaaag aacccccagt aaatcatgga tataagtatt agcaaaacta
    58261 gacaaccatc ctgaaaggaa catccctccc aataaagaca gaatcaaaac cttctttggc
    58321 aattcccatt tttcccaata cggaagagaa aataaagagc cggaatcatg taaaagagag
    58381 ctagaaagat agaaattccc attagtccat attccgcacc tgacctcgaa ccgtccgtat
    58441 agtagatggt ttcatactgt aaaccaatac atagcaataa aataaaaata aataaaatac
    58501 tgcttttctt catacacttt ctttctaaat gaagtattta taattctacg actgtcatac
    58561 ttcctgtatc aacattgtaa atagcaccag agataatgac atcgtctggt attaggggag
    58621 actcgataag cagttgcata tcctcgcgta cactctcttc tatatcttgg aagggcaaga
    58681 agtcctggtc tgacacatct acacctaatt cctcttttaa atactcctga aaaggttcat
    58741 tttcaaaggt ctgagcacca cagtctgtat ggtgcaatac cacaatctct cttgtcccca
    58801 tttgttgctg ggaaataact agcgaacgaa tcatgtcttc agtcactcga ccacctgcat
    58861 tccgcaagat atgagcatcc ccaagtgcca agcccagagc ttgcgcaacg tgcagacgag
    58921 agtccataca ggtcacaata gctactcttg ttttgggttt aagtggcaga tttaactgcc
    58981 catgtagggc aacataagcc tgattggctt gcataaactg ttcaaaatac gacacgattc
    59041 cctccttgaa aatttgatag tcaaatattt ctcctatctt atcattttta agagaatttg
    59101 tcacggatta tgcaaagacc tttttcaaaa cttcctgaat cgttgtcacg ccaatgacct
    59161 gaatttcctt aggcagagtg attcctgtca aggaattctt aggtacataa atcttagtaa
    59221 agcccagttt agcagcttcg ttgatgcgtt gctcaatacg attcacgcgc cgaatctctc
    59281 ctgtcaagcc cagttctccg acaaaacatt cctgaggatt agttggtttg tctttgtagc
    59341 tcgaagcaat agcaactgca acagccaagt caatggcagg ttcatccaat ttaacaccac
    59401 cagcagattt gagataggca tcctgatttt gcaagagaag ccctgcccgt ttttccaaaa
    59461 cagccataat caagctagca cggttaaaat caagtcctgt cgtagtacgc ttggcatttc
    59521 caaacatggt cggtgttact aaagcctgaa cctccgccaa aatcggacgc gtcccttcca
    59581 tggttacaac gatggaggaa ccagtcgccc catccaaacg ctcttctagg aaaacttgac
    59641 tcggattgag tacctcaacc aagccgcccg actgcatctc aaaaatccca atctcattag
    59701 tggaaccaaa acgatttttg accgctctca aaatacgaaa ggtgtggtga cgctcccctt
    59761 caaagtaaag caccgtatcc accatatgct ccaacatacg aggcccagcc aaggttcctt
    59821 ctttggtcac atgacctacg ataaagatgg caatgttatt ggtcttggcc aactgcatga
    59881 gttcagcggt cacttcacgt acctgagaaa cagacccctg cacccctgaa atctcaggag
    59941 acatgatggt ctggatggaa tcaataataa gaaagtctgg ctggatacgc tccacttctg
    60001 cacgaacact ctgcatattg gtctctgcat agagataaaa ctcactatca atatcaccta
    60061 agcgctctgc acgtagttta atctgctggg cagactcctc cccactgaca tagagaactg
    60121 tccccacttg ggacaactgg gttgagactt gttggagaag agttgatttc ccaatcccag
    60181 gatccccacc gatgaggacg agacttcctg gtaccactcc gcctccaagc acacggttga
    60241 attcctccat ctccgtcttg gttcgattga cattgatgga agtcacctca gctagtttca
    60301 tgggcttggt tttctcacct gtcaaggaca cacgcgcatt cttgacctcg gcaacctcaa
    60361 cctcttccac aaaagaagac caagatccac agttggggca acgtcccaga tatttagggg
    60421 aattataccc acaattttga catacaaatg tcgctttttt ctttgcgatg acaaacctct
    60481 tcctatatct ctaactcaca ctcaatcact tggcaaaaat caatcttctc atttggcaca
    60541 aactggcgca tgagcattcg atgagcaaca actaccacag tctgatgttc tcgatactta
    60601 gacatacatt ctagaaaccg agacttcatt tccgtagctg tctcatattg aataggacta
    60661 ttaggaagca actccccctt gttttctaaa aacagtcttc tagctgtttc aaagttttct
    60721 attcctgttt tatagacctg ccattcatgt aataaaggct ctactcttaa aggaagaccc
    60781 gtagcacaga ccacatacga agccgtttct aaagctcttg tgactgcaga agatacgatt
    60841 atttcagctg acgagagtaa aggatttttg ctcaatttct ggacttgctg ccgtcccatc
    60901 tcagacaagg gtgccaaatc tatcccaaat cctatataag aacgctcctc taactcacgg
    60961 taatctggct ccccatgacg tacaaagata atcttcattc tagtgccctg tcgatccaaa
    61021 tccaccagtt cgaacgccac cagctgcatc tccatctgca attaagaaag tagcaaaaac
    61081 agcctggaca atacgttccc caacttcaag aacaacctct tggtctgtga tattcttcat
    61141 ctgcgcaaaa atatgccctt catttccagg atttccataa taatccccat caatgacccc
    61201 aactgagtta attaaaacca agcccttctt acgaggattt gaagaacgat catagaggta
    61261 gagaacctca gtcggctgca tataagcctt aacccctgtc ggaaccaaga caatctctcc
    61321 tggcgcaaca actgtacgca cagcaacctt taagtcgtaa ccagccgcat gcgctgtctc
    61381 acgcttgggc aataaatttt catctgtaaa acttgaaacc aattcaaaac cacgaatttt
    61441 cataattttc tcttttctat tatcatttat tctagattat tctatcttat ttattcggaa
    61501 aaagcacgaa aaaagagcac acaattcaaa tcgcttaggg ctgctggatt cctcccctga
    61561 cccgcttcac gcagaactgt tgctccacta tttattatat cacattccta ttcattttaa
    61621 aagcaaaatt attttttccg tctatttcta aaaaaatcct gcatgatagc tgcgcattca
    61681 tcttccaaaa ttcctatttc aacctccaca cgatgattga gacgctcatc tgtcaagata
    61741 ttgtacaaac tcccagcagc gccaaatttc tggtttttag ccccatagac cacatttgga
    61801 atgcgggcaa gcccaatcgc tccactacac atgacacaag gttcaatggt cacaaaaagt
    61861 gtgcaatcca gcaagcgcca gctctcctca ctcaagttcg catcctctat agccataatt
    61921 tccgcatgca taaccgctcg ctgtaattcc tcacgcgcat tatgcccacg accaatgatt
    61981 tccccatctt tgacaatcac acaaccaatt ggaatttcat cgtgttcaag agcaatctca
    62041 gcctctctca aagcctccct cataaagact tctttttctt caagcgtata atacatctct
    62101 tttctctttt cctacttatc gattttatta ttatatcatg aatcccaaca caaaaaaagc
    62161 caccgaatgc ggtgactcta tagggagatt attatgaaaa agaaaagttt aggatatttg
    62221 ttacaacaag ttaggaggtc ttcttgtaac cgtctatagt atacccgacc tatcttaaac
    62281 aaatcttaaa aatctcttag gaccaaacac tttctaaaat atttgtttgt tcacgaccag
    62341 gacctactga gaaagtagaa atacgaacgc caaccaattc actcacacga cgaacatagt
    62401 tacgcgcatt ctcaggaaga tcttccaaat tgcgaactcc ggtaatatct tctgaccaac
    62461 ctggcaactc ttcatagata ggcttgcaac gtttcaattg ctcaagacta gctggatagt
    62521 agtcaatacg ttgaccgtca agatcatagg ccacacagat tttcacagta tccaaaccgc
    62581 tcaaaacatc aatagagttc aaagaaaggt tagtaatacc agaaacacga cggctatgac
    62641 gcatcacaac tgagtcaaac caacctacac gacgtggacg accagttgtt gtaccatact
    62701 catgacccac ttcacggata cgttctccca cttcatcaaa caactcagtt gggaaaggac
    62761 catctcctac acgactcgta taagctttac atacacctac aaccttgtca atcttgcttg
    62821 gaccgacacc agaaccaatt gtcacaccac cagctacagg gtttgatgac gtaacaaatg
    62881 gataagtacc ttggtcgata tctagcataa caccttgtgc accttcaaaa agcacacgtt
    62941 tgccattatc aagcgcatca ttcaagataa cagatgtatc tatcacgtat ttcttgattt
    63001 gttgaccata ttcgtaatat tcttcaaaaa tatcatcgaa aacaatcgct ttactgtcat
    63061 acaatttttc aaaaagacga ttcttttcag caaggttacg ttctaaacgc tcacggaaaa
    63121 tatctttatc taaaagatct gcaatacgaa ttccaacacg agcagccttg tccatataag
    63181 ctggaccaat tcccttaatt gtcgtaccaa tcttattgtc gcccttagct tcttcttgca
    63241 agcgatccaa ctcgatatga taaggcaaaa taacatgcgc acgatcagaa atacgcaagt
    63301 tatcagttgt tacaccttcc tcatgaagat agctcaactc ttttacaaga gatttaggat
    63361 ttacaaccat accattccca atgacagata ttttttcagg gaagaaaatc ccagatggaa
    63421 tcaagtgcaa cttaaatttc ttaccgtcaa tcacaatcgt gtgaccagca ttatcaccac
    63481 cttggtaacg tgcaatcact tctgcattcg ctgaaaggaa gtctgtaatc ttccctttac
    63541 cttcatcacc ccattgggta cctacaacaa caactgaagt cataatcttg tctgagccct
    63601 caggctcttc ctttctcaca tacatggcag gactctcacc tgcaattata tcttacaatt
    63661 tattataata aaaaatcgcc tttttatcaa gaagaaacaa tagaaagatt tgctatttcc
    63721 aactattaaa a
//
LOCUS       DBJKQU010000008        49996 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.008, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000008 DBJKQU010000000
VERSION     DBJKQU010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 49996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.008"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..167
                     /locus_tag="ACSUUC_000558"
     CDS             <1..167
                     /locus_tag="ACSUUC_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HHQ8053832.1"
                     /translation="KNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQLEIRVQSQKK
                     SNGLDVGKAD"
     gene            617..2632
                     /locus_tag="ACSUUC_000559"
     CDS             617..2632
                     /locus_tag="ACSUUC_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HHQ8053833.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTTGEGLLSYNLILLSISLFFTQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            2634..3266
                     /locus_tag="ACSUUC_000560"
     CDS             2634..3266
                     /locus_tag="ACSUUC_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053834.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(4194..4607)
                     /gene="ndk"
                     /locus_tag="ACSUUC_000561"
     CDS             complement(4194..4607)
                     /gene="ndk"
                     /locus_tag="ACSUUC_000561"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HHQ8053835.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(4718..8395)
                     /gene="rpoC"
                     /locus_tag="ACSUUC_000562"
     CDS             complement(4718..8395)
                     /gene="rpoC"
                     /locus_tag="ACSUUC_000562"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HHQ8053836.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(8428..12039)
                     /gene="rpoB"
                     /locus_tag="ACSUUC_000563"
     CDS             complement(8428..12039)
                     /gene="rpoB"
                     /locus_tag="ACSUUC_000563"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HHQ8053837.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSSLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            12455..12525
                     /locus_tag="ACSUUC_000564"
     tRNA            12455..12525
                     /locus_tag="ACSUUC_000564"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12487..12489,aa:Cys,seq:gca)
     gene            complement(12723..14054)
                     /locus_tag="ACSUUC_000565"
     CDS             complement(12723..14054)
                     /locus_tag="ACSUUC_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HHQ8053838.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(14345..15169)
                     /gene="endA"
                     /locus_tag="ACSUUC_000566"
     CDS             complement(14345..15169)
                     /gene="endA"
                     /locus_tag="ACSUUC_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HHQ8053839.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(15208..15396)
                     /locus_tag="ACSUUC_000567"
     CDS             complement(15208..15396)
                     /locus_tag="ACSUUC_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HHQ8053840.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(15389..16672)
                     /gene="murA"
                     /locus_tag="ACSUUC_000568"
     CDS             complement(15389..16672)
                     /gene="murA"
                     /locus_tag="ACSUUC_000568"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HHQ8053841.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(16696..16926)
                     /locus_tag="ACSUUC_000569"
     CDS             complement(16696..16926)
                     /locus_tag="ACSUUC_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HHQ8053842.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(16984..18021)
                     /locus_tag="ACSUUC_000570"
     CDS             complement(16984..18021)
                     /locus_tag="ACSUUC_000570"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HHQ8053843.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(18005..18493)
                     /gene="coaD"
                     /locus_tag="ACSUUC_000571"
     CDS             complement(18005..18493)
                     /gene="coaD"
                     /locus_tag="ACSUUC_000571"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HHQ8053844.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(18483..19022)
                     /gene="rsmD"
                     /locus_tag="ACSUUC_000572"
     CDS             complement(18483..19022)
                     /gene="rsmD"
                     /locus_tag="ACSUUC_000572"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HHQ8053845.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19087..20079)
                     /gene="asnA"
                     /locus_tag="ACSUUC_000573"
     CDS             complement(19087..20079)
                     /gene="asnA"
                     /locus_tag="ACSUUC_000573"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HHQ8053846.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(20190..20873)
                     /locus_tag="ACSUUC_000574"
     CDS             complement(20190..20873)
                     /locus_tag="ACSUUC_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HHQ8053847.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(20929..21669)
                     /locus_tag="ACSUUC_000575"
     CDS             complement(20929..21669)
                     /locus_tag="ACSUUC_000575"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HHQ8053848.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVATGILIFHLS"
     gene            21703..21981
                     /locus_tag="ACSUUC_000576"
     CDS             21703..21981
                     /locus_tag="ACSUUC_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HHQ8053849.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22059..22985
                     /gene="yidC"
                     /locus_tag="ACSUUC_000577"
     CDS             22059..22985
                     /gene="yidC"
                     /locus_tag="ACSUUC_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HHQ8053850.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAVKQRSR"
     gene            complement(23060..23854)
                     /gene="pflA"
                     /locus_tag="ACSUUC_000578"
     CDS             complement(23060..23854)
                     /gene="pflA"
                     /locus_tag="ACSUUC_000578"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HHQ8053851.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(23980..25230)
                     /locus_tag="ACSUUC_000579"
     CDS             complement(23980..25230)
                     /locus_tag="ACSUUC_000579"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HHQ8053852.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(25297..26124)
                     /gene="purR"
                     /locus_tag="ACSUUC_000580"
     CDS             complement(25297..26124)
                     /gene="purR"
                     /locus_tag="ACSUUC_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HHQ8053853.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(26391..27332)
                     /locus_tag="ACSUUC_000581"
     CDS             complement(26391..27332)
                     /locus_tag="ACSUUC_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HHQ8053854.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(27322..28578)
                     /gene="rmuC"
                     /locus_tag="ACSUUC_000582"
     CDS             complement(27322..28578)
                     /gene="rmuC"
                     /locus_tag="ACSUUC_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HHQ8053855.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(28580..29242)
                     /locus_tag="ACSUUC_000583"
     CDS             complement(28580..29242)
                     /locus_tag="ACSUUC_000583"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HHQ8053856.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(29205..29861)
                     /gene="rpe"
                     /locus_tag="ACSUUC_000584"
     CDS             complement(29205..29861)
                     /gene="rpe"
                     /locus_tag="ACSUUC_000584"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HHQ8053857.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(29872..30750)
                     /gene="rsgA"
                     /locus_tag="ACSUUC_000585"
     CDS             complement(29872..30750)
                     /gene="rsgA"
                     /locus_tag="ACSUUC_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HHQ8053858.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(30752..31624)
                     /gene="rsmA"
                     /locus_tag="ACSUUC_000586"
     CDS             complement(30752..31624)
                     /gene="rsmA"
                     /locus_tag="ACSUUC_000586"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HHQ8053859.1"
                     /translation="MRIADYRVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(31755..32063)
                     /locus_tag="ACSUUC_000587"
     CDS             complement(31755..32063)
                     /locus_tag="ACSUUC_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053860.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(32056..32697)
                     /locus_tag="ACSUUC_000588"
     CDS             complement(32056..32697)
                     /locus_tag="ACSUUC_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053861.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(32699..34729)
                     /locus_tag="ACSUUC_000589"
     CDS             complement(32699..34729)
                     /locus_tag="ACSUUC_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HHQ8053862.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVHLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYIP
                     SGNVIYVSPRYLIEEKITVSSEFIDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(34806..35102)
                     /locus_tag="ACSUUC_000590"
     CDS             complement(34806..35102)
                     /locus_tag="ACSUUC_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HHQ8053863.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(35422..36333)
                     /locus_tag="ACSUUC_000591"
     CDS             complement(35422..36333)
                     /locus_tag="ACSUUC_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HHQ8053864.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     EDLFYEQLPNEEKVWFEATRATIDVIRSGRPEYGETVLDDYFKTIYDKELFLINELEV
                     INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIASEYLFALSNTLFSGLACL
                     DNLSSYDSLGAYIFSLNHIMEKTQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSK
                     LFADIIENSYLVTMLEKQWQEDLKKYL"
     gene            complement(36405..36965)
                     /gene="rnmV"
                     /locus_tag="ACSUUC_000592"
     CDS             complement(36405..36965)
                     /gene="rnmV"
                     /locus_tag="ACSUUC_000592"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HHQ8053865.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(36965..37738)
                     /locus_tag="ACSUUC_000593"
     CDS             complement(36965..37738)
                     /locus_tag="ACSUUC_000593"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004536 - DNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HHQ8053866.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELLLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(38043..38762)
                     /locus_tag="ACSUUC_000594"
                     /pseudo
     CDS             complement(38043..38762)
                     /locus_tag="ACSUUC_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_367670414.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
     gene            complement(38971..39105)
                     /gene="rpmH"
                     /locus_tag="ACSUUC_000595"
     CDS             complement(38971..39105)
                     /gene="rpmH"
                     /locus_tag="ACSUUC_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HHQ8053867.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(39250..40464)
                     /locus_tag="ACSUUC_000596"
     CDS             complement(39250..40464)
                     /locus_tag="ACSUUC_000596"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHQ8053868.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKKLLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(40620..40913)
                     /locus_tag="ACSUUC_000597"
     CDS             complement(40620..40913)
                     /locus_tag="ACSUUC_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053869.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            41075..41527
                     /locus_tag="ACSUUC_000598"
     CDS             41075..41527
                     /locus_tag="ACSUUC_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HHQ8053870.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(41562..42950)
                     /locus_tag="ACSUUC_000599"
     CDS             complement(41562..42950)
                     /locus_tag="ACSUUC_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHQ8053871.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            43016..43978
                     /locus_tag="ACSUUC_000600"
     CDS             43016..43978
                     /locus_tag="ACSUUC_000600"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004067 - asparaginase activity [Evidence
                     IEA];
                     GO_process: GO:0006528 - asparagine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HHQ8053872.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(44274..45284)
                     /gene="ccpA"
                     /locus_tag="ACSUUC_000601"
     CDS             complement(44274..45284)
                     /gene="ccpA"
                     /locus_tag="ACSUUC_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HHQ8053873.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(45709..46308)
                     /locus_tag="ACSUUC_000602"
     CDS             complement(45709..46308)
                     /locus_tag="ACSUUC_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHQ8053874.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDITILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(46310..47407)
                     /locus_tag="ACSUUC_000603"
     CDS             complement(46310..47407)
                     /locus_tag="ACSUUC_000603"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHQ8053875.1"
                     /translation="MLERLKSIHYMFCASLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTVFVAGNYIWFLFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     ERVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(47407..48144)
                     /locus_tag="ACSUUC_000604"
     CDS             complement(47407..48144)
                     /locus_tag="ACSUUC_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8053876.1"
                     /translation="MKRWIALNKIEFLLTKRQLVYYLLSVGMPTAFYLFFSGIYQETP
                     GGPANFMRDYLISMTAFSMMSTAMFSFPAVLHTDKINNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVEIPLGSWVGAAILLILGSVAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(48146..49030)
                     /locus_tag="ACSUUC_000605"
     CDS             complement(48146..49030)
                     /locus_tag="ACSUUC_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053877.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(49017..49211)
                     /locus_tag="ACSUUC_000606"
     CDS             complement(49017..49211)
                     /locus_tag="ACSUUC_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053878.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(49208..49414)
                     /locus_tag="ACSUUC_000607"
     CDS             complement(49208..49414)
                     /locus_tag="ACSUUC_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053879.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        14437 a        11371 c         9505 g        14683 t
ORIGIN      
        1 agaaaaatcg tggaattcaa aaattagcta tattagtatt actaggtgtt tttatgttta
       61 gtaacacaat tccttaccaa cagtttattc agaagaatag acaattggag attcgagtgc
      121 aatcacaaaa gaagtccaat ggtcttgatg ttgggaaggc tgattgattt cgtattactt
      181 taaaattcaa ctatttagag aaaggtattc tgatgagagc ttgtaacaat accagataga
      241 tataagaatg gagatgtttg ataaaatgct ttcatagcta accaactgtt gaaaattatg
      301 agttacaaaa tctaaagtat ttaagattgg tttataaaat taggtctctg cctgtagaaa
      361 ggaacgtgca gttagaaagg aggaaaaaat aggatactat aattcagact gagatttcta
      421 attaaaatat gtagttgcat ttcgctcatt ttcataatat ttcattcaga ggagtaataa
      481 tatgttaaaa tttagatttg atgcgggatg gtaaagaata attgaagaag attcttttat
      541 caatagttta gtaagcttgt tagtttatag agggcagggg tatttctgcc ctctgtttta
      601 gaataaggaa tgcactatga aaaaattatt tatactcata tccaacctgc ttgctagttt
      661 gttctttgtt tgggtattta ccatttggac tgatacatat gtctcccatt attaccccaa
      721 cgttgttgta cgtgattctt cccctgaaac aacttttcag catgttgcta cacgcttgga
      781 aaaactagca gaagaaacag atagctttat tgcgattcaa caccaagatc ctaactcaga
      841 aggtactaca gttttttctt atacgacctt tggggacgga aagttgcctg atgggcttca
      901 ggaaaaaaat ctagaagatg ctcaaagtag tagtgttgaa acaaactatt ttgtattcga
      961 tggacaccta gatattcact tgctaaggga agagctaagt caacttggct tgactaacat
     1021 gcacctgaca attccatcta aactatctac gttaatggct atctttagta acggatttca
     1081 gttaatcagt ctattgattt tcatcttaac ctttgtagca ctgactttaa ttagtcaaat
     1141 tagccaatta cggtcatcgg gcattcgcct catttcagga gagaaacggt ggtccatttt
     1201 ccttagacca gttggtgagg atttgaaagc gatagctgtt ggtttcagtt tagctggcgt
     1261 gctcgccatt cttatgcaaa aaattctgtc gcttccaacg caatccctaa tgaccacagg
     1321 agaaggcttg ctcagttata atctcatctt gttgtcgatc tccctgtttt tcactcaact
     1381 cttcgcagtt gggataaaaa agatacacct gatgcagatt ataaaagggc aagtgcctgt
     1441 cagaggaatc attagtttga ttttaatcgg tcaactatta gcgattatta ttgtaacgct
     1501 gggaataggg agtagcttaa agtattccca agcctggcaa cagcatcgga ttggacaaga
     1561 ggtttggagt caggaaaggc aactgattac cctatcaatc agccgtgaag gaacgagtcc
     1621 tggttttgat gaacaagctc aaaggaaact cagaacttgg tatcaattga tggatctggc
     1681 tgtttcagaa caaaaggctt tcttatctag acaccagtta attgaccgta ctttgcaaaa
     1741 tggcatggct tcctccaaaa acttgataac ctctacagaa tggcacgatt acaacccgaa
     1801 tggcaatgtc cttatcgtca caccgcaata cttggagcgt caaaacattc ctgtagatac
     1861 aactattgag caaaagatga atcaccttga tgtaggggag tttgtcttat tgctgcctga
     1921 acacctccgt tcagaggaag aacattataa atctgttttt gaagacgact taaccagtcg
     1981 catgtctagt caagatgaac gacagcaaat gactgctacg gtaggttatt tagaatcagg
     2041 tcaggatcgt tttgtgtata atacgacccc tatttcttac cagcagtttt tgaaagatcc
     2101 aatcatcatt gttataacac cccaatcaac tggtccacag tccattttgt tttggataga
     2161 cgcagtacag aactacgttc tctttaatca attgtctgat gcccaggagc ttatccagag
     2221 acaaggcatt gaaaattggg tctcagaaat gcaaacaggt taccacaact acatcacatt
     2281 attggataat atccagaggg aacgttgggt aatgctagca ggagctgtgc ttgggattgc
     2341 aacttcaatc ttgttgttta acactatgaa taggctctac tttgaagaat ttagacgtgc
     2401 catttttatc aaacgcattg caggtctcag gttcttagaa atccatcgca cttatctctt
     2461 tgctcaactg ggtgtgtttt tactgggatt tgttgcgagt gtatttcttc aggtagagat
     2521 aggagttgct ttcttagtct tgttactctt tactggtcta tctcttttac agttacatgt
     2581 ccaaatgcag aaagaaaaca agatgtccat tcttgttttg aagggaggtt aatatgattg
     2641 aacttaaaca ggtgagtaaa tcttttggag aacgagagtt attttcgaat ctttcaatga
     2701 catttgaggc tggaaaagtc tatgccttaa ttggttcaag tggtagcgga aaaacaacct
     2761 tgatgaacat gattgggaaa ttagaacctt atgatgggac gattttttac cgaggtaaag
     2821 acttggccaa ttataaatcg agtgattttt tccgtcacga attgggctac ctcttccaga
     2881 actttggctt aattgaaaac caaagtattg aagaaaacct taagctaggt ctcattggtc
     2941 aaaagttgag tcggtcggaa cagcggttga ggcagaagca ggctttagaa caggtcggcc
     3001 tggcttatct tgacctagat aagcgcatct ttgagttatc gggcggagaa tcgcaacggg
     3061 ttgccttggc aaaaattatc ttaaagaatc caccctttat tctggcagat gagccaacag
     3121 cttcaataga cccagcaacc tctcagttga ttatggagat tttgctatct cttcgagatg
     3181 ataataggct aatcattatc gcaacacata atccggcaat ttgggagatg gctgatgaag
     3241 tgttcacgat ggatcatctg aaataaaaat ccttgttttt aattgcacga tgagttactg
     3301 aaatattatc atgaatcaag aattggagtt aatttagaat tgtactttat taatattgag
     3361 gtaacttttt cttgataaag gaagaaataa tggagaggaa gttagaatga aaaaattcga
     3421 caattatatt attgagaagc cttgcgattc taattcagat aaactgcaaa aaatcttaat
     3481 aattgaaagt ttggtagatg atattttgca attttctctc agaatcaata atagtgtagg
     3541 agagattttc ctcctacaac cgttttaaaa gaaaactatc tttattccat gttattttga
     3601 ggaagatatt gtgaaagtca aagatgatga taaagttgag tggaatttgt tagaatttca
     3661 aaaatttaga gcatttttgg cttagtaatc tgtgttgaag gctcaaaacc tatggtaaaa
     3721 aagtcgcttt gaaaacgtat tgcctccaaa gatttagtta aataatgatt taacacaaaa
     3781 agaaattatt gaagttctgg aaagatgttg tttcagtatt gagaaaaggt gggaaaaact
     3841 tgcgattttc acagagaaag gaagaaaaag tatagaaata tagtcaattg aaacaagaac
     3901 aggataaaag aaccttttgt gccatatttt tctcctttcg ctttacaatt ggcttgaaca
     3961 cctttattgt atcgcgtttg gagttttttt ggtataacct tcgacgcgca cccgcatagc
     4021 gggtgttttt ttgtctcgca cctaacggag cgagacgaac taatagtcac ttaatcaaaa
     4081 aacgcaccat atcaaaaact aaaaagtttg atatcatgcg tcatgtctta aactaattga
     4141 ctatactttc tattcaaatg agcttttaac caattgattg agccaatcca ctcttaaaac
     4201 caaagagcaa tttctcgctt agctgactct tctgaatctg aaccatgtac aacattttgg
     4261 ataacctcat tttctccagc agcttttgca aagtcacctc gaatagtgcc tggtaaagct
     4321 tcttctggac gagttgcacc catcatggtc cgccaagttt cgattacttt gggaccagaa
     4381 atgacaccca caagaactgg acctgaagtc atgaattcac gaatcggtag gtaaaaactc
     4441 tgaccaacca agtcctgata gtgctggtca atcaactctt ctgaaacctg tgaacgaaac
     4501 tccaattttt cgattgtaaa tccacgttgt tcgatgcgct ttaacacttc acccactagc
     4561 cctcttttta caccatctgg tttgatgata aagaatgttt gttccatacc cgtctccttt
     4621 gtcagcttct ttcttttatt ttaccacatt tcgtggaaaa atggagaaag ttttcagaag
     4681 agagaatgag agaacccgag ggttctctca ttctctctta ttctactgtt tcttccacag
     4741 tttcaacggc agtatccaca actacttctg ttgtttcttc atttccttct tcctctactg
     4801 gaggattaag gtattcttct tcgttgacag catgtggttc aaggttacgg taacgggcca
     4861 taccagtacc agctgggatg atcttaccga tgataacatt ttctttaagt ccaaggagat
     4921 ggtctttctt accacggata gctgcgtcag taaggacacg agttgtttct tggaaggaag
     4981 ctgctgacaa gaaactgttt gtttcaagtg aggctttggt aattcccata aggactgggc
     5041 gacctgtcgc tggaactcca cctgcgataa ggacatcttt gttggcatct gtaaagtcat
     5101 tgatatccat gagggtaccc atgagaagat ctgtatcacc tggatccatg acacggactt
     5161 tacggatcat ttgacgaacc attacctcga tgtgtttgtc accgatttct accccttggc
     5221 tacggtaaac tttttgtact tcaccgagaa ggtacgtttc aactgacaag acatcacgaa
     5281 ctgcaaggag acgttttggt tggatagaac cttctgtcag agcagcacca cgcgctactt
     5341 ggcccccaac ttcgacacgc atacgagctg taaatggaac gacatattca ccttcgccag
     5401 tttcaccctt aacaaagact ttcttggtac gagttgatgc atcttcttcg atagcagtaa
     5461 cttgtccttt aacctctgtg ataaccgctt cccctttagg attacgggct tcaaagattt
     5521 cttggacacg aggaagaccc tgagtgatat cggtatttga ggcaacccca cctgtgtgga
     5581 aggtacgcat tgtaagctgt gtaccaggtt ccccgataga ttgggcagca attgtaccaa
     5641 ctgcttcacc aacttcaacc gcatcaccag tcgccaagtt tataccgtaa cagtgacggc
     5701 agacaccgtg acgagtgtta catgtaaata cagaacggat agtcacttct tccacaccag
     5761 cattgacaat ttcacgcgcc ttgtcttctg taatcaattc atttggacca ataatcactg
     5821 caccagtttc tggatgttta acagttttct tagtgtaacg accgttgaga cgctcttcga
     5881 gagactcgat catctctttt ccttctgcga tagaacggat caagagacca cggtcagttc
     5941 cacagtcgtc ctcacggatg ataacgtctt gggcaacgtc gaccaaacga cgagtcaagt
     6001 aacctgagtc ggctgtctta agggccgtat cggtcatacc tttacgagca ccgtgagttg
     6061 agaagaacat ttccaatacc gacaaacctt cgcggaagtt tgaaaggatt ggcaattcca
     6121 tgatacgtcc attcggagca gccatcagac cacgcatacc ggcaagctgt gagaagtttg
     6181 agatgttacc acgggctcca gagtccatca tcataacgat tgggttctta ggatcttggt
     6241 tagcaatcaa gcgtttctca agtttttcac gggcagcacg ccattcagct gtaacagcat
     6301 tgtaacgctc gtcgtctgtg atcataccac gacggaattg tttggtgatt tgctcgacac
     6361 gtttgtgtga ttcttcaatg atttcagcct tgtcatcaac gactgggata tcggcaatac
     6421 ccactgtcaa tcctgcaaga gttgagtggt ggtaaccgag attcttcatg cggtcaagta
     6481 gggcagaagt ttctgtcgta cggaaacgtt tgaagatttc agcgatgata tttccgaggt
     6541 ttttcttctt gaatggaggg ttgagctcaa gattgctgat agcttccttg atatctccac
     6601 caagtggcaa gaagtattta gctggaacac cttctgtcaa gttggcattg tttggttctt
     6661 gcaagtatgg tagcccctct ggcatgatat cgttgaagag aattttacca actgttgtaa
     6721 gcaagacctt atgtctttgc tcttctgtcc aaggcttgtt gaggctgtct gttgcgatac
     6781 caacacgtga gtggaggtga acataaccat tgcggtaagc cataaccgct tcgtcacggt
     6841 ctttgaagac cattccttca ccttcgcgac cagcttcttc catggtcaag tagtagttac
     6901 ccaaaaccat gtcctgagat ggagtaacta ccggtttccc atctttcgga ttcaagatgt
     6961 gctcagcagc tagcatgagg atacgagctt ctgcttgtgc ttcttctgaa agtggtacgt
     7021 ggatggccat ttggtccccg tcaaagtcag cattgtaggc ttcacagaca agtgggtgca
     7081 agcgaagagc cttaccatca atcaagactg gctcgaaggc ttggataccc aaacggtgaa
     7141 gggtcggtgc gcggttcaaa agcactgggt gttctttaat cacttcttca aggatatccc
     7201 agatacgctc atctccgcgt tccaccaagc gtttagctgc tttgacgttt tgcacgatat
     7261 cacgggcaac gatttcacgc atgacaaatg gtttaaagag ttcaatcgcc atttcacgtg
     7321 gcacaccaca ttggtacatc ttaagagttg gaccaacggc gataacggaa cgtcctgaga
     7381 agtcaacacg tttaccgagc aagttttgac ggaagcgtcc ttgtttacct ttaagcatgt
     7441 ggctcaatga tttcaatgga cggctacctg gtcctgtgat tggacgacca cgacgaccat
     7501 tgtcaatcaa agcgtcaact gcttcttgaa gcatacgctt ctcattttga acgatgatac
     7561 ctggtgcatt taactcaagc aaacgagcca aacggttgtt acggttgata acacggcggt
     7621 aaaggtcatt caagtcagat gaggcaaaac ggccaccatc caactgcaac attggacgaa
     7681 gatctggtgg gataaccgga agaatgttaa gaatcatcca ttcaggtttg tttccagact
     7741 tgtaaaaggc atccaaaaca tccaaacgac ggatggcttt gacacgtttt tgtccagtag
     7801 ctgttttcaa ttcttctttg agttcagcaa tttctttttc aagatctact tgcttcaaaa
     7861 ggtcttggat ggcttccgca cccatcttgg caacaaatga accataacca tattcacgca
     7921 agcgctctcg gtattcgcgc tctgtcatga tagacttgtg ctcaagtggt gtatccttag
     7981 gatcaatcac cacataagcc gcaaagtaga taacttcctc gagggcacga gggctcatat
     8041 caagggtcaa gcccatacgg cttggaatcc ccttgaagta ccagatgtga gatacaggag
     8101 ctttcaattc gatatgtccc atacgctcac gacgaacttt cgtacgcgtt acttcaaccc
     8161 cacagcggtc acaaacaatt cctctgtaac gaatgcgttt gtacttacca caagcacatt
     8221 cccagtcttt tgtaggacca aagatcactt catcaaagag tccttcacgt tctggtttca
     8281 aggtacgata attgattgtt tcaggttttt tgacttctcc ataagaccat gaacggactt
     8341 tacttggaga agctagggtg atttgcatac ttttaaaacg atttacatca accactattt
     8401 cttccctttc tattctaagt gaactgctta ttcttgttca gcagcttctt ctgttgcttc
     8461 cgcttttgtt gctttctcag cttcttcagc ttcaaaggct gctttagcct cttgagctgc
     8521 tttttcgcgg gctttttcaa ggtcatctac gtggatgaca tcttcgtcca ttccttcatc
     8581 caagtcgcga agttccactt cttggtcatc ttcgtctagg acacgcatgt caagaccaag
     8641 agattgcaat tctttgacaa gaactcggaa ggattctgga acacctggtt ttggaattgg
     8701 tttgcctttt gtaatagctt cataggcttt caaacgtccg ttgatatcgt ccgacttgta
     8761 agtcaagatt tcttgaagga catttgacgc accgtaggct tcaagagccc aaacctccat
     8821 ctcaccgaaa cgttgtccac caaactgagc tttacctccg agtggttgtt gggtaacagt
     8881 tgagtaaggt ccgactgaac gcgcatgcaa tttatcgtca accatgtggt ggagtttgat
     8941 catgtacatg actccaacag aaacacggtt atcaaatggt tcacctgtac gtccatcgta
     9001 aaggattgtc ttggcatcgc tatccatacc tgcttcttta acagttgacc aaagatcttc
     9061 agaacttgct ccatcaaaga ctggtgtcgc aatgtgaata ccaagagtac gagctgccat
     9121 accaaggtga agctccataa cctgaccgat attcatacgt gatggcaccc caagtgggtt
     9181 caacatgatg tcgactggag ttccgtctgg aaggtaaggc atgtcttcta caggaacgat
     9241 acgagagaca acccctttgt ttccgtgacg tccggccatt ttatctccga ccttaatctt
     9301 acgtttttga gcgatgtaaa cacgaaccaa catgttaaca cctgattgca actcatctcc
     9361 atttacacgt gtaaagatct taacatcacg aacgacacca tcggcaccgt gtggtacacg
     9421 aagagaagta tcacgcactt cacgagactt gtctccaaag atagcgtgca agagacgttc
     9481 ttcagctgaa agatctttct cacccttagg tgttacttta cctacaagaa tatcaccttc
     9541 tttaacctca gcaccaatac ggataatccc catttcgtca aggtctttga gggcatcttc
     9601 accaacgttt ggaatttcgc gagtgatttc ttcaggccca agctttgtat cgcgcgtttc
     9661 tgattcgtat tcttcaaggt gaacagatgt gtagacatcg tccttcacca agcgttcgct
     9721 catgataacg gcatcctcga agttgtaacc ttcccaagtc atgtaggcaa cgattgggtt
     9781 ttgtccaagc gccatttctc cattttccat agaaggtccg tcagcgatga aatcgccttt
     9841 ttcaacgaca tcaccaactt ttacgagagt gcgttggttg taagcagtac ctgagtttga
     9901 acgacggaat ttttggatgt ggtaaacatc caatgaacca tcttcacgac gaacttctac
     9961 cttgtcagca tctgcgtaag taactttacc atcatactga gcaatcacag ccgcaccaga
    10021 atcgtgggct gcttggtatt ccataccagt accaacgtaa ggtgcctgag gattaatcaa
    10081 tggcacagcc tgacgttgca tattggctcc catgagggca cggttggagt catcgttttc
    10141 caagaaagga atacatgctg tcgcaacggc aactacctgt tttggtgaaa cgtccatgta
    10201 gtcaacaata ttagctggat actcttggtt gaccccttgg tgacgtccca tgacaatctt
    10261 ctcagcaaag gttccatctt cattcagact agagttagcc tgagctacag tatattcatc
    10321 ttcttcatca gctgtcaacc aaacaatttc gttcgtgaca acacctgttt cacggtcaac
    10381 cttacggtat ggtgtttgaa caaaaccata tttgttcaag tgtccgtaag atgacaagtt
    10441 attgatcaaa ccgatgttag gtccttcagg tgtctcgatt ggacacatac gaccatagtg
    10501 agtgtagtgc acgtcacgta cttcatatcc agcacggtca cgagtcaaac caccaggtcc
    10561 taaggctgac aaacggcgtt tgtgagacaa ctcagaaagc gggttgtgtt ggtccatgaa
    10621 ctgtgacaac tgtgatgaac caaagaattc tttaactgca gctgttacag gacggatatt
    10681 gataatttgt tgtggtgtca agacttcatt gtcctgaaca gacatacgtt cacggacatt
    10741 acgttccata cgagaaagtc ccaaacgtac ttggttggca agcaattcac caaccgcacg
    10801 gatacgacga tttccaaggt ggtcgatatc atctacacgg ccaagtcctt cagccaagtt
    10861 gaggaagtag ctcatctcag caaggatatc tgcaggagtc accgtacgaa ccttgtcatc
    10921 tgggttagca ttaccaatga tcgttacgac gcgatctgga tcagttggag caataacctt
    10981 gaatttttga agaacaacag gctcagtcac aacggctgca tcgtttggga tgtagacaat
    11041 cttgttcaag tcgccatcca aatggctttc aatgctttca atcacgctac gagtcataat
    11101 cgtaccagct tctaccaaga tttctccagt ttcagggtct accaatggct ctgcaatggt
    11161 ttggttgagc aaacgtgttt taacattgag ttttttattg attttgtaac gaccaactgc
    11221 tgccaagtca tagcgacgtg ggtcaaagaa gcgagccaca agcaagctac gtgagctttc
    11281 agccgtctta ggctcacctg gacgaaggcg ttcgtaaatt tctttcaagg cttcgtctgt
    11341 acgagagtcc attggattct tgtggatatc tttttcaaca gtgttgcgaa ccaattcgct
    11401 gtcaccaaaa atatcaaaga tttcatcatc acctgagaaa ccaagagcac gaaccaaggt
    11461 tgtaaatgga atcttacgag tacggtcgat acgagtgtag gtgatatctt ttgagtcgct
    11521 ttcaagttcc aaccaagctc cacggttagg gataacagtt gaaccatagc ccaccttacc
    11581 atttttgtct actttgtcgt taaagtaaac acctggtgag cggaccaact gagaaacgat
    11641 aatacgttca ccaccattga tgatgaaagt acccatttct gtcatgattg ggaaatcacc
    11701 aaagaaaact tcttgggtct tgatttcgcc tgtttcttta ttgatcaagc ggaaggttac
    11761 aaaaattggt gctgagtagc tagcatcgtg aatacgagct tcttctagcg tgtattttgg
    11821 ttccttgatt tcatatccaa caaattccaa ctccattgtg tctgtgaagt ttgaaattgg
    11881 caatacatct tcaaacactt ccttaagacc gtggtctagg aaagctttga atgagtcagt
    11941 ttgaatttca atcaaatttg gtaagtcaag aacttctttg attcttgaaa aactacgacg
    12001 ggtacgatgt ttcccgtatt gaacgtcatg tcctgccaag atgattctcc tttgtaaata
    12061 agttccaagc cttgtcaatc aggcttttct aatcgccata tggttgtaaa ccccttatca
    12121 ccgtgtcctc ttgacgaatt ttcagaatct ttaagcctct gttacaaatg ctcaaaatct
    12181 tgaaaaaaag cacaaaaaga gcagctaaat ctgacttttt cagaagattt aactgctgtg
    12241 agccttgtct ggacaatatt tcagacaaaa cctacgacaa atgattaccc atattatacc
    12301 ctatttagct agatttttca aggggattca gtaggttttt ggtaattttt ttcccataga
    12361 aaacttggca tcacattcga atcacgctat ggtacaaaaa actgaaaaaa ctattgactg
    12421 aaaatcattt tcaaggtata ataataaacg ttaaggcggt atagccaagt ggtaaggcac
    12481 ggctctgcaa aagcttgatc gtcggttcaa atccgtctac cgccttctat aacttgattt
    12541 atcaggtttc aaatgaacag aaagcccaat ttgaagggct ttttttattt tccctcgaat
    12601 aaatacgtat aactttaaaa acttttggag cgagtttgtg gcagagttct ttccatggca
    12661 taattccctt ttgaaatcaa ttgaaaaaag cttcgtcacg cctggtgaca aaagcctcta
    12721 gtttattctg tttcttcttc tatttcgact tctgtgattt ggacttttac cttggtaaca
    12781 cgtccattct tcactttatc attggttaag ataaactgtt tgttttggct gaccaattca
    12841 tagctgagtt tctcagtcgt tggaatggtt cccactcctg tcaaataata accagcgatg
    12901 gtatcaacgt catcactttc cagttcaaca tcaaagtaat tattgaaatc attgagggtc
    12961 atagttcctt gaacaatgta ggtatcctcg ccaatctgat gaacatctat tgctgcttta
    13021 tccgtttcat catcaatttc accaacaatt tcctctaaga ggtcttccaa agtcactaaa
    13081 ccagccatac caccgtattc atccagcaag attgccattt gtctttgggt atttcgcagt
    13141 tcttttagca agtcatccac aaaaatagtt tcaggtacaa aaagtggatc ttgtaaaatt
    13201 ctcttccaaa caatattgtc aaaaccgtcc acaaagcctg ccttaaggag actcttggtg
    13261 tgaatgattc caattacatt gtccttatcc ccatcataaa ccgggatacg agaataattt
    13321 tgttttaaaa tactttggat aatggcttga ctatcatcct gaatatccac cataaaggca
    13381 tccgttcgag gaaccataac ctctcgtgcc atcagttcat cgagcgaaaa gacaccttgt
    13441 agcatctcaa tctcatcagc atccaatgtt tcttcactat ttgtcagcat ataggcaatt
    13501 tcatcacggg tcatcttttc atccgcatca tcgaatgaca taggagtcaa atggctcaag
    13561 aaattggtcg aagcagctaa aagccaaaca aaaggactga ctagttttcc gatcccaatg
    13621 ataaccggcg ctgtacgaat tgccaaggca tcctttagat taagagcgat tctcttagga
    13681 tataattccc caaaaacgat ggaaatatag gtcaaaaatg ccaaggatag aaaagttgcc
    13741 acggcttgtg ctgtttcgcc attcccaagc caagaggcaa tcacacgtcc tagagtatca
    13801 gttaaactcg cccctgataa gattgtaatc agggtgattc ctacctgaat ggttgataaa
    13861 aagtggttag gattttctag taccttcagc aggcgaatgt agcgtctgtc tccttcttcc
    13921 gccttttgtt caactcgggc acgattaaga gaaaccatgg ccatttctgt ggctgagaaa
    13981 aaggcattta ataccgtcaa gataaacaat aaaacaaatt gtagcaacaa attctgacta
    14041 cttgggtctt ccatagttct tctcctaaaa tagtatctta tcctttatta tatcacaaaa
    14101 tttaatccaa tacatattat ttttttctta gcgtaacttc catctctctc ccaaaactgg
    14161 aagttagtct aagacggatt tccactgatt tcacgcgttt ttctcatact aaaagctagg
    14221 ttgtgggaaa ctggaagtta gttttagaag ttactatttt ttcttagtac ctgttctagc
    14281 cctgcttaaa ctagtaaaaa gaactcctac atccataagt gacataggag tttaggctta
    14341 tcttttactg agttacagtt acttctccag ttcggtaatc cagttgaagt cccttttgaa
    14401 cattgggaac tagaacattg aattccaatt ctccatccga agacttggct tcaatctgtg
    14461 aagctgaggg aactaaatcc tcgtttgaag cgtagtaaag ggttacacgg taacggacac
    14521 gcttgttttg gtccaaggct ttacgcacct tgctttcata gtagttttga ccagtcgaat
    14581 actcggcttg tgcctgattt gcccaggctg tctgaacagc aatgttttta ggattgcttg
    14641 ttgaggcatc aaaaccatcc aaaccaccga ttaaggcata gcctaacaaa tgacctctat
    14701 cgactgcatg ggtataagag ccctttagat tcttgacctg atgccaacct ggaggagtcc
    14761 aagaagttga accattccca gtttctttac gattcttgta ctgacgagtg gccttagaca
    14821 agagggcatt agctacggtt ggaacagttt ccttgcccac tgtctttgtt ttattgtcag
    14881 cgtagggctt acttgaaacc ttggcatcta gatttgtttt attaccattg acgataaaag
    14941 cacctgagcc attccactcc agactcccct ttatttgact cttgactgcg tctgttaaga
    15001 cactctctgc caatgcttga ctaggagctt caggcgcttg ttttttctga ctaagcttgg
    15061 ttttaggact attaggtgcc gactgcatct gcttgatata atagctccct gtagacaaaa
    15121 gcaataacac tagcagtccg attagtgtct gtcttgtttt tttgttcata tttctcctta
    15181 tctttagaaa aaggctggtt ctccagccta atttcctgta aatttatgaa tcaattcctg
    15241 ccattttgct ggagacagga tagcccatgg atcttgaccc ttgcccaaga ttccataacc
    15301 taccattaaa ccgattccta gagccagagt acctaaaatc agtactatga tgactaaaag
    15361 taaacgcttg actacgtagc ttgatttctt attcatcttc atcacttgcc tcaatccgct
    15421 gaatcttagc acctagctgc gccaacttct catggaaacc gtagtaacct ctatccaagt
    15481 gaaccaattt accgaccaca gtttctccct gtgctaccaa acctgtcaaa atcaaggctg
    15541 cactggcacg aaggtcagtt gaaagaactt ctgctccctg caaaggctgt ccaccaacaa
    15601 tacgagctgt atcacggata atctcagaat gcaagcccat gcggcgcatc tcttctaggt
    15661 gttggaaacg attttcgaaa actgtctcca ccatggttga ttcgcctttt gcaactgtca
    15721 tcaaggctgt aaattgagcc tgcatatctg ttggaaatcc tgggtggggc aaggttttca
    15781 catgaacagc ttttagattt tctagttgag aacgaacacg aattccttcg tcttcttcaa
    15841 ttacttcaac acccatttca agtaacttgg caatcaaggg acggttgtgc tcccagacag
    15901 cgtctcgaat caagacatca ccaccagtca tggcagcagc taccataaag gttcctgctt
    15961 cgatacggtc ttggactaca ttgtgagtcg taccatgaag tttctcaaca ccagtaatgg
    16021 ttatagtctc tgtaccagca cctttgacct tggctcccat ttcattaagg agaatggcta
    16081 agtcaacaat ctcaggctca cgcgcagcat tctcaatcac tgtcacccca tcagccagag
    16141 tcgctgccat catcaagttc tgcgttgcac caacacttgg aaagtccata tagatatgag
    16201 cgccatgcaa gcgttctgcc ttggcttcga tgtaaccagc tgtctgacta atcttaaccc
    16261 ccatagcttc cagacctttc aaatgaagat caataggacg gctaccaatc gtacaaccac
    16321 ctggcatgga taccttggca tgacccacac gggcaaggat tggccctaat acaacgatgg
    16381 aggcgcgcat cttgctgaca tacttgtaag gggcttcctc agtgatgtcg ccagtagcat
    16441 ccaccttgac aagatgagct tcctcatcaa agtcaacctt ggcattcaaa ccaccaacta
    16501 cctgattcat aataaagaca tccgacaaaa tcggaacatt ctgcaagacg gtctttcctt
    16561 cacttgctag aatagtcgct gccaacaagg gtaagactgc attttttgct ccctcgatcg
    16621 tcacgcttcc taccagacga ttatcgccac cttgaaccac aattttatcc atactcgttt
    16681 cctttactct tgatttcata ataatcctct aagcgcttct tgccacaaat gatacaggct
    16741 aataaagaaa gaactcagga tgtagcctat gacaatgcta aaaaaggcta ctaataaacg
    16801 aacttttctt gtattatcat ctgtcacttt taaaaccttc tcccatctaa caagatcctt
    16861 taaaaggtaa aaactcacat aaataaagaa catatgacta cttagagtga ataataattg
    16921 aaccatttga ctattatacc atcttctctg tttgtgcgct agtttggaaa cttcactcaa
    16981 aaattaggga ttgtttttca agtaatcaat cgcatcttgt agggttttaa cgggcacgat
    17041 tttcatatcc gtcttgattg ttttagccgc ttctagggct gtttggtagt tgtttttcgc
    17101 gtccggatgc gccttttgtt cttcttcgct aacagggtta tcaggagcaa agaaaatagc
    17161 agcacctgcc ctagccgaag ctacaacctt cttatcaata cctccaatgt ctcccacatt
    17221 accatcgcgg tcaatggtac ctgtaccggc aacaatacga ccattacgaa gatctgggtg
    17281 agctatttga gtatagatag ctagactaaa catgagacca gcacttggac cgccaatacc
    17341 agctgttgaa aagctaattg ggacattgct gattacctct gtacggtcaa tcaagccgat
    17401 tccaattcca tttttgccat tttccaaggt gatgattttt ccttctgcag acttggtttg
    17461 cccatcctct tcataggtga ccttgacgga atcccctaat ttttgagaac tgacgtaatc
    17521 aatcaagtct ttggaactat caaaggtctg atcattgact gctgtgactg tatcagagat
    17581 attgagaatc cctttaaagg ttgaattatc cgtcacattc aaaacataaa ctccaaagta
    17641 cttgagttcg atatccttac cagctgtttt tagtccttga tacttggcca tattttgcga
    17701 tgtttgcatg tagaattgat tgattcgcat aaattcaaca tcggaagaac cacctgtagt
    17761 ctcctgagca ctacgaatat ctgtaaaagg tgtcaaccaa gcataaatca tatgagctaa
    17821 agtggcatgt tgaacaccaa ccgtaacgaa ttgataggca ccagcttcct tatcttctgt
    17881 gtcatttact ttaaggactt ggcgaatatc ttccgaacca cctggaacct ctatataata
    17941 aggcaagggc actacaaatg ccaagaaagt cacaatcaag gccgcaatga cgtataaggg
    18001 ccatctaatc ttttttttca tttcttattt cctccaaaat actctcggga acatagcagg
    18061 caatatcctg accaaacttc aaaagctctc taacgcctga tgaactgata tagagatgtt
    18121 caggtcgact atgtaaataa atagtctcta tatcagaaga cagctgatga ttgtagtaat
    18181 caaaactggc ttcatattgc aaatccgacg catttctcaa gcctcgcact aggcaagtag
    18241 cccccagtct ttttgcgaca tcgaccacca atttatcatg agaagacacg actttaacat
    18301 ttcccaaatg tttcacagcc ttttctaacc cccgtttacg attttcaaga gggagaaatc
    18361 cttgtttgtg gggattaaaa aaaataccca cataaagctt atcaaagagt ctgctcgccc
    18421 gttcaatcat atccagatgc ccatttgtca tcggatcaaa tgagcctgtg aataagccaa
    18481 tcttatctga catagactgt caccttacta attccataaa tcttttcctt ccagataccc
    18541 agacaggcaa tctcttctgg aagttcaacg gccttatccg tctcgcacac aaccataaca
    18601 tcttcagaaa aaagctctct ctcagccatt ttttcaatat ctgctacgat ttgttccttg
    18661 gcatagggag ggtctaagaa aacgaggtca aattccccag atacctgttc caatgccctc
    18721 tctgcatcca tcttgaggag ttgaaatttt ccaacttcct tggtcatctg gatattttca
    18781 gccacgatgg tctgagcctt acggtctcgc tccaccaaaa cagcactgga catgccacgc
    18841 gatactgctt cgatagataa accaccacta cctgcataaa ggtccaagac tcgtccccct
    18901 tcaaagtagg gaccaatcat gttaaaaatg gctcccctaa ccttatccga agtaggtctt
    18961 gtcgtcttgc cttctagtgt cttgagggga cgtcccccat agattcctga tacgattttc
    19021 atactgttta ttataccaaa ttatagacaa aaagagaaag aaaaccgaac cttgcggttc
    19081 gattctctac aaaatatttt cgtaagtatc gcggacttct tgaggccaaa cacttgtttg
    19141 cacttctccg atgtgtctct tgcgaagtag gaacatggcc atacgagatt gtccaattcc
    19201 tccaccgatt gtcaatggga atagaccatt caacaaagac ttgtgccatt ccaattccaa
    19261 gcggtcttca tcacctgtaa tttccacctg acgtctaaga gtttcttcat ctacacgaat
    19321 tcccatagaa gacaactcaa aggctccacc taaagactca ttccagacaa gaatatcacc
    19381 atttagaccc ttgtagccat tctcagactc gcttgtccag tcatcatagt ctggtgcacg
    19441 tccatcgtgc ggtttaccat ctggcaactc gccaccgata ccaatcaaaa agacggctcc
    19501 aaattcttta caaatcgcat tttcacgttc tttcggtgtc aagtctgggt agcgttctac
    19561 caattcttct gtatggataa aggtgatttg ttttggcaag atagactcga tgtcatagcg
    19621 ggcttcaaca gctagctcag tcaggcgaat agccttataa atcttctcaa ctgtttcttt
    19681 tagataaacg atgttacgct taccatttgg gataaccttc tcccagtccc actggtcaac
    19741 ataaacagag tgggttgcat ccaaggaatc ctcatctgga cgaagggctt tcatgtggac
    19801 aaagagaccc tctccttcac caaagccaaa acgagccaag gtgtggcgtt tccatttagc
    19861 aagtgagtgc accacttcat aagtagcatc agggatttgg agaaccttga ccgatactgg
    19921 attttccaca ccagacaggt tgtcctgcat tccgtcaccg accttactca agataggacc
    19981 ttgaacttcg acaacttcta gcttatcttt caaatactgg gtaaaagtgt ttttgacaaa
    20041 ggaaatttct tcttgttgat ggataaaact tttcttcata gacaactcct caaaaattta
    20101 ataaacgtat tatacaccta tttccaagaa aagaaaagag aaaatttaaa aaaatcagtg
    20161 tcactcaaaa cactgatttc atagaccttt tagtcattgc gaccaaagat acgtagaata
    20221 cttaggaaaa gattgataaa atcaagatag atgctgagag ccattgacac cacccagcct
    20281 gtcgctacac gaccttgtga ttgttcatag gcgaggcgaa tcttttggtt atcccaagca
    20341 atcaaccctg aaaaaaccaa aaccatggct acgctaatca tataatcaaa gaagccacta
    20401 gccaagaaaa tattgactac catagcaatc agtaaaccaa tgagagctgc catcattgct
    20461 cgaccaatcc cactcaagtc tttcttggta aagataccaa ctgccgccat gacaaagaag
    20521 agaagggcgc tcgatacaaa ggcagataaa actgtacccg gagtatagaa agccaccaca
    20581 aaactaaggg taaagccgtt taaaacggag taaagtaaaa atactggaag agcagctgga
    20641 ctatttcttg aagccatgct actggcaacg aaaaccaaag ccaactccgc aaaagtagca
    20701 atggtcaacc agagacgccc ctgcatcaac aagtaaacca actgagactg aaagaccgtc
    20761 aacataaggc ctgataccaa agcagatagt ccgattccca gaccaacaaa ggcataaacc
    20821 ttagcgtaaa attgattgag acctgcacgg tcatgtataa tagtgtgatt catccttttc
    20881 tccttttctg tgaacatctt tccttgatta taacaaaaaa agttaaaatt agcttaaatg
    20941 gaagattaaa ataccggttg caactgcaac attcaaactc tcggcctgcc ccttcatgct
    21001 aatatggacc aactggtctg cactttcagc cataagggga ctaattcctt gaccctcatt
    21061 tcccataact agtacaaaat tttctataga aggcagttct ctgtaatcaa cagaatcttt
    21121 agatagggtt gttgctagca ctgggatagc taccttttta gtttcgtcaa gaagcgcttg
    21181 actagtcatc cggtaaatgg gcagatggaa atgactacct tgcatggaac gtagggtttt
    21241 gagactgtag atgtctgccg acttatctga aacaatcact cctgtaaaac ctgctgcatc
    21301 cgcagttcga atgatagttc ctacattacc aggatcttgc acatcttcca aaaacaagaa
    21361 cttgccctga ctcaaatcag cttgtcctac ttcttctttt tgaaccacgg caacaattcc
    21421 ctgtggagtc tgagaatccg ccaaatctag caaaatatcc tctgaaatcc agacagtttg
    21481 cggaaaagca gctaactgat ttcgataatt ttctagggca aagattttct caatcgtcac
    21541 tccagcttgg acagcttctt caaacaagtg ccagccttca atcaaatagg cagacttgcg
    21601 gtattttttt tggtgtaatt tcttggcatt ttttaccaca gaattggctt ttgaggttat
    21661 aatagtcata gaaatattat aacacaatca aaggggtttg gtatgcaaaa ggttagaatg
    21721 attgcccaag gtagggtgca gggagtcggc tttcgttggg gtgtttatag cctggccctt
    21781 gaaatcggtg gcatcacagg tcgggtatgg aataacgacg atggcacagt ggaaatctta
    21841 gcccaagcag actcatctgc tatcatggca aaatttatcc aagaaatccg aaaaggaccg
    21901 acaccttttt caaaagtaag ctacttagat gtcaaactaa gcaactttcc tccctactct
    21961 gactttaaaa tcgcaaatta ggtctccaga actattgtat attttgtaaa aaaacagtag
    22021 aatagaaagg tataattttt aaagaaggaa taaaaacagt gaaatctatt aaacgttttg
    22081 cattctcggc tatgggagtg gctatgttgc ttgtcttgac tggctgtgtc aatgtcgata
    22141 aaaccacagg tcagccaaca ggatttattt ggaatacgat cggagcgcct atggctgaag
    22201 ccatcaagta cttcgctact gataaaggtc taggctttgg tgtcgctatc attatcgtaa
    22261 ccattatcgt acgcttgatt atcttaccac ttggtatcta ccaatcatgg aaggcaacgc
    22321 ttcactctga aaagatgaac gctctcaagc atgtccttga gccacaccaa acacgtctca
    22381 aagaagcaac tactcaagaa gaaaaactcg aagcccaaca agccctcttt gccgctcaaa
    22441 aagagcacgg catcagcatg tttggtggtg taggatgttt ccctatcctc cttcaaatgc
    22501 ctttcttctc tgctatctac tttgctgccc aacatactga aggggttgct caagcaagct
    22561 acctaggcat tcctctaggt tctccaagta tgattttggt tgcctgtgct ggtgtccttt
    22621 actatcttca atcgctcctt tcacttcacg gagtagaaga tgaaatgcaa agagaacaaa
    22681 tcaagaaaat gatttacatg agcccactca tgatcgtcgt cttctccctc ttctcaccag
    22741 ctagtgtcac actttactgg gttgtcggtg gtttcatgat gattctccaa cagtttatcg
    22801 tcaactatat cgttcgtcca aaacttcgca aaaaagtccg tgaagaacta gccaagaacc
    22861 caccaaaagc aagtgctttc tctaaaccaa gtggacgaaa agacgttacc cctgaacaac
    22921 caactgctat cacaagcaag aaaaaacaca aaaatcgcaa cgctgtaaaa caacgttcga
    22981 gataagaaga aaaaggctta gctaatttgc taagtctttt tgcaaatcaa aagcccgatg
    23041 tttccatcag gcttcttttc tatccatgta cacgtttcat ataatcttga taactttcgg
    23101 tatccatgag ttttttagcg ttcttgacgc gatctgctgt tggtggtttg actccttcga
    23161 gggaatatgg aattccaagt tcacgccact tgaactcacc catggtgtga taaggtagaa
    23221 tttcaaactt atcaacattt ttgagggtct tgacgaactt accaagttca atcaagtcat
    23281 catctctgtc tgtcaatcct ggaactagca cgtggcgaat ccagacaggt tttccaatat
    23341 ctgatagata ctgggcacaa gccaagatat ttttattagt ttggctagtg acaatcttgt
    23401 gctgttcttc gttgatttcc ttgatatcca aaagaaccaa gtcagtgaca gccatgagtt
    23461 tgtcaaactt ctcaaggtaa cgtggtttat tacggaaagg aagagcacag gtatccaagg
    23521 tacagtggat tccttgttcc ttagccttgg tgaagagagc aatcaggaaa tcaatctgca
    23581 agagagcttc tcctccactg actgtaatcc cacccttatt tccccagaaa ccacggtagc
    23641 gcaaggcctc tgtcaagaca tcatctactg tccgttcacg tgacttattg gactccatag
    23701 cccaagtgtc tgggttgtgg caatactggc aacgcatgtg acagccctgc aaaaagacaa
    23761 taaagcgaat accaggccca tctactgacc caaagctttc tgtcgaatgc accattcctg
    23821 tcacttgtcc ataatcaatt gtttcttcag acatatcgtt accttccttg aaaacgtttt
    23881 atagttttat tatatcacga cttgaaggaa aaacaagatt tttgcctatt ttttagaaag
    23941 caatctgttt ttcaatttca ttttcaatct attatcagat tattcttcaa aatcgaagcc
    24001 atataaggtt gcaaaatagt cctcagggcg ctctgcacgg cggatttgac gggctttacc
    24061 ttcttcggta tagaggattt ccgcagaacg taatttggca ttatactggt agcccattga
    24121 aaatccgtgg gcacctgtat catgaattac cagcaaatca ccgatttctg tatgaggcag
    24181 ttcgcgattc actgcaaatt tatcattgtt ttcacagagt gaaccaacca catctaccgc
    24241 ttcagctggt ccatctggat gggtcacgtt gctaatatga tggtaagctc cgtacatagc
    24301 tggacgcatg aggttgactg ctgaggcatc cacacctaga taggtacggt aggtttcctt
    24361 cttatgagtc actcttgtga ctagagcacc gtgaggtgcc agcataaaac gacccaattc
    24421 ggtgaaaatc ttgacctgac caagacctgc tgacgtaaga acttcttcat acaccttacg
    24481 aactccctca ccaatcaagg cgatatcgtt cggctcctgg tctggacgat aattaacacc
    24541 aataccgcca gaaagattga taaagtctag cgaaatgccc aacttttcct tgatttcaac
    24601 agccagttca aagagctgac gagccaactc tggataatag agatgggtca cggtattgga
    24661 cgctaggaag gagtgaatcc caaaagtctt ggctcctttt tccttcaaga tagcaaaggc
    24721 ttcaaagagc tggtccttgg tcatgccaaa cttagcctcc ccaggattgt ccataatgtc
    24781 tgtccccagt tcaaaaacgc ctccaggatt ataacgacaa gagatgattt ctggaatgcc
    24841 tgctactctc tccagatgtt caatatcttc aaaggcatcc aagttaatgg tcgcacccaa
    24901 ttcacgtgca taggcgtatt ccttgtctgg cgtgttgttg gaagagaaca taatctcaga
    24961 acccagaaag tccagtttat ggctcatcaa aagctctaca taactagagc agtccacacc
    25021 acaaccttct tcttggagaa ttttcaaaat agctggagtt ggagtagcct taactgcaaa
    25081 atattcctta aagcccttgt tccacgaaaa agcttggttg acggctcttg ccttctcacg
    25141 aatccccttc tcatcataca agtgaaaggg agtcgggaac tcggcaacaa tcgcttctaa
    25201 ctcttctcta ttgataaatg gtgttttcat aagcttcctt ctattctgtt tgcaaagaaa
    25261 ggctgggaca atcgttccaa cctttagttc tatctcttat ttatcttcgt caaagatatt
    25321 gccaacctca acatcgatgg cttggttctt gacatcaata ttggttacct tcaagagtga
    25381 cttgtagtca aactgctttt cacgttcttc ttgggcattg tccgcaaaga ccgctacacc
    25441 tgccagttct gagtcgaact cgcgcaagag actaatcata ccattgaccg ttccgccacc
    25501 tttcaagaag tcatccacaa tcaagacacg gctgcctgcc ttaagactac gttttgaaag
    25561 gaacattttc tcgatacggt caccacttga acctgaaaca tagttgacgc taacagttga
    25621 accttcggta attttcaggt cacggcgcac aatgacaaaa gagacattga ggacattggc
    25681 aactgcattt gcaagtggca cacccttagt tgctacggtc ataaccgcgt caattttttg
    25741 gtccataaag cttttggcaa taatacgacc aatatttttc aagatggctg gtgtgctaag
    25801 caaatcagac agatagatat aaccacctgg caagatacgg tcactttctg acaacttggt
    25861 acgcaagtct tcaaccattt ccttagcatc ctgactcgaa atagacggtg tgaagatgac
    25921 acctccgcca gccccagtca ctgtctggat atgaccgatt tcaatttcct caaaggcgcg
    25981 tttgataatg acgatatctt ctgagatgga tgatttagca gactcatact tttcagcaaa
    26041 agtattgaga ctagttagtt tataaggatt attaatcaaa tagttggaaa tgacaaccat
    26101 ccgatcactt cttcttaatt tcatttctat ttcctattcc atttttattc aaaaaatcaa
    26161 aaagcaaact agaaagctgg tcgctggtgg ttcaaaacac tgttttgaga ttgtcaatag
    26221 aactgacaaa ccctgtaata tacctgcata tatacatacg acaaggcgat actatcctag
    26281 tttgaagaga ttttcgaaga gtattcattt ttgtctttta cttattatac catattcaca
    26341 taaaaaaacg aacattctta tcctaaaaaa tgctcatttt tcttaaatta tcaatctaaa
    26401 tctggtttat agaaggaacg attatccata gcgaagattt tattggtcat ctctccttta
    26461 tccaccaaag ccagagctgt tgacatcatc atcatgcttg catccagatt gtcaatcata
    26521 tggataatct ctgcctccat aatacgtgga cggactggac ttccatattc aagcaagccg
    26581 tggtgactga ggatgacatg acgaagcaaa acgacttctt ccttggtatc atcgatgccg
    26641 agttccataa ctgtcttggt aatttcgcta tcaatgagag cgatatgtcc aagaagatta
    26701 cctcgcactg tgtactctgt ctggtctggc cccgtcaact cgataacctt agctaagtca
    26761 tgcagcataa tccccgcata gagcaggctc ttattgagct gaggataaac ttcgctaata
    26821 gcgtctgcca aacgcaccat ggtcgccgta tgataggcca agcccgtttc aaaggcatgg
    26881 tggttggtct tggcagctgg ataggagtag aattccttat catacttggt gtagagattt
    26941 cggacaatcc gttgccagac aggattttca attttgaaaa tcatttgcga catgtagtca
    27001 cgaatttcct tgacatcaac tggtgacttg accttgaaat cagctgggtc attgggttca
    27061 ccagcttgag gcaggcggag agtaatttga ttgacttgag gggtattgtt ataaacttct
    27121 cggcgtcctt tcatgtggac aaccttacct gcggtaaagg cctcaatgtt atgaggttgg
    27181 gcatcccaga gcttcccatc aatctcgcca ctatcatctt ggaaggtaaa ggctaggtag
    27241 tttttcccag ctcgagtttg cctcaggtca gctgatttga ttaggtaaaa gccttcaaat
    27301 aactcatctt ttttcatgtg actaatcttc atattcttcc tcattttctt gaaaatggag
    27361 tagatcaagc gcaggctcac cttctgacaa ctcaatgtga cggagcgtcc gctcgatagc
    27421 tatggtacga cggtttaata attcatcaat attgccagag gcatgttgga gatgtttttg
    27481 tgccttgacc agaataccac caaacttgcc aaactcggtc ttgacactgg caagagtctt
    27541 gctgatatgg tcggcactct tttggatatt aagggtcttg aaaccaactg atagggagtt
    27601 aagaagggct gatagggtac ttggtcctgc aacgataatc tgttcttccc gtctcaaatc
    27661 atcaaagaag accggattgc gcacaatctc tgaataaaga ccttctgtcg gaacaaacaa
    27721 gattccaaaa ttggttgtcc gaggcggtgc tatgtacttg ctcttgatat ccttggcaaa
    27781 gcgcttgacg cttgctagga gtgacttacg acagcgttca atctcatcct tgtcacctgt
    27841 ctcataggct tcttccaagc ggtaataatc tgccagtgga aacttagagt caattggcag
    27901 atagacgtat tcttggtcgc cttgtccggg taacttgatg gcatactcca ctcgttcact
    27961 agagttttca accgttgcgt attctcgttc gtactgggca ggtgtcatga tgtcttcaat
    28021 aatttgcccc agttgcaatt ctcccagaat acctcgcgtc ttggttccag agagaacctt
    28081 gttaagagct ccgacatcac gggcaactgt ctgcatttct ccaaggccac gattgacaga
    28141 ctccagttgt ttagaaactg tttcaaagga agcctgtaag cgtgtctgca aggtcttttc
    28201 tagtttttcc tcgaccgtct ggcgcatttg ttccaaacgt tgctcatttg attcctgcaa
    28261 ggcttggaga cgttggtctg tcttgtctct agtttggagg agattatctg tcatttcttg
    28321 acggacttgg gtcaggcctt ggtgcaattc aatccgcact tcttgcaaac ggtcgctgac
    28381 agccacttcc aaatcttttt ggtctaactg gctggcttgt ctggcttggt caaagcggta
    28441 atccaactgg tctgacaaat gatctgcctg atcctccaag ctcttactta agtgtttctc
    28501 ctgcctatcc tgcctttgcc aaatcagaaa gagaccagct aggttggcaa ttaataatag
    28561 aataagtaaa ctttccatcc tacctcctgt ccttgctatg cagtacgacc acataaccat
    28621 ctgggcaagt taccgacact tccctatcta tatattcgtt agaagcgtac acttttttaa
    28681 agaaaaaatt ctcctctgtc aactcatact tagctccaag aatagtcagc tggctatccc
    28741 gaactggcat aaaggctaga tagtcgtagt ctgaacgagg ttctagctga ctggtccctt
    28801 ctgaacaata ggcaatcaaa ttttgcccat cctcaatttc tatttgacgc atatagggtg
    28861 ccaacttagg attgctaggt agaaagacat tggccaacat atggtcaata cggccaccca
    28921 aggcaccgaa aatagtgacc tgagcctgag gattttgttc aaagatggtt aagagagcca
    28981 attccagatc tgtatcatcc ttttctggtc gggcttggac aaaatactgg gcacgttttt
    29041 gaatcacctg tcgctcttct tccgtcacag aatcaaaatc tccgactgct agagcaagag
    29101 gtaagtcttc ttccaagacc cagagcgagc ctcgatccac cccaacaaaa gcatcaaaat
    29161 ctgtccgata atgaccgcgg tttccgcctg caaaaactgc aaccctagtc cagttgtttt
    29221 ctgagagttt gtactcgctc attgacttct cccttaaaga cataggaacc tgctacaaaa
    29281 acagtcgcac cagcttcttt ggcttgagca atagtttggt catcaatccc accatccact
    29341 tcgatttcaa agttcaaacc tttttcctca cgaagagcaa ccaactcacg aaccttatcc
    29401 atggtttctg gcagaaaggc ttgcccacca aaacctggat taaccgtcat gactaaaact
    29461 tggtcaacta gatgaaggac gtgcttgatg gcttcaactg gtgtgccagg attgataacg
    29521 actgaaggct taactccgag tgaacgaatt ttttggaggg cgccatgaat atgaggtgtt
    29581 gcttctacat ggatactgat gatgtctgca cctgcacgcg caaaatcttc cagatgatgc
    29641 tcagggtttg acaccatcaa gtggcaatcg aaaaccatct tactatgagg acgaaggctc
    29701 tcgaccacac ctgcaccaaa actgatttgc ggtacaaaat gactgtccat gatatcgata
    29761 tgggcatatt ctgccccagt tgcttctaga cgtttgattt cacgttcaaa gttggcataa
    29821 tctgctgcca gaattgacgg agcaatcttg tattgagaca taggtttctc cttattttgg
    29881 aatttttttg ctgacttttt tataggtttc tctacgattt tcaatttcac taaggaattg
    29941 caggtaattg tcaaaacgga aggttgcaat aacaccctct tcaacagctg gtttgacggc
    30001 acaagacggc tcatgggtat gggtacaagt acggaactta caatctcggc taacagtagc
    30061 aatctctggg aaagcctgat tgaggtcttc agcccttgat acttcatagt ccaaggatga
    30121 aaatcctggt gtatctgcga ttttaccccc gttgagattg taaaaactaa cagctcgagt
    30181 ggtatggcga ccgcgaccta gactgtctga aatttctccc gtttcaagat tgaggtctgg
    30241 tgcgatttta ttgagaagag ttgacttccc aacacctgtc tgccccataa agaccgtaac
    30301 cttgcctgtt aacaaagaca ggagttcctc tttactggtc acaaagtcat agccgatgtc
    30361 accataggtc tgctggtaaa aatccagttc tcccctatct tccaacaaat ccattttgga
    30421 aatatagaca atgggatgga tgcccttgtg ctccaaaaga accaagaaac gatccagcaa
    30481 attgctgtta aaatcaggtt ccttgacgga catgattact acagcttgat cgatattgac
    30541 aataggcgga cgaaccagac tgtttttccg ttcgtgaatt ttgaggatat agccttctga
    30601 attttcctcg gcagagaaat ctacccagtc cccaacataa ggggtatggc cttttttacg
    30661 gaaattccca cgcgcgcgtg tttgataaac ctggccatca ctctccacat agtagaaacc
    30721 tgccaaggct ttaatgattt gtccctgcat cttagagtcc ttgcccttta agtgcgtctg
    30781 ctagaccggc aaattctgcc aagctgagag cttccccacg cacacttggt gacaagcctg
    30841 cctggtccaa agccttggtc agcttgtcct tgacctcttc agtcttacca aagtaacctg
    30901 tcaagttatt ccacaaggtc ttgcggcgat gggtaaaact agccttggaa accttaaaga
    30961 aaaagttctc atcttctact gctacggctg gctctggacg acgcaccatt ttcaagatgg
    31021 ctgaatccac atttggcgct ggcacaaaga ccgtacgagg cacgataaag gcaaccttgg
    31081 ctgtcatgta atactgcacg gcgatagaca agctaccgta agccttggtg ttaggctggg
    31141 ctgaaatgcg gtccgctact tctttctgca tcatgaccac aaactcacaa aaaggaatgc
    31201 cactctcaat caagtgcatg agaataggcg tcgtgatgta gtaaggcaaa ttagccacta
    31261 ccttgattgg caggttagga tttttaaaat tttggatatg ttgcgccaaa tcaaccttga
    31321 gaatatcttc gttaactaca gtcacattat caaaatcacg cagggtatct accaaaattg
    31381 gcaccaaacg gtggtcaatc tcaaaagcca tgacttgggc tgcacgctca gccagaaact
    31441 ccgtcaaggc accaatacct ggcccgattt cgatgacatt gacctggtca tcaatttcag
    31501 ccgtatccac aattttttga aggatattgg tatccgtcag gaaattttgc ccgaaggact
    31561 ttttaaaggt aaaaccgtga cgctccagca ctgccttggt cactctataa tctgcaattc
    31621 tcatctattc tcttttctat tatctgttac tactattgta acacattccc cttgtatttt
    31681 gggaatgaaa atcataccaa aaaactatct ttcctcatga agaaagatag tcttggaaat
    31741 ctttaaaagt ggccttaaca gttctctcga aacatgcgtt caaaaaaatc agcttcttga
    31801 taacttcgat tttcaggtag ggtcaaatcc acatcctcct ccacatcatc cactgtcagt
    31861 tcaaccgtct gaggtaaatt tttcaaacga taatgctttt gcctttgccc ttcaatacta
    31921 gcaaaatcaa gcaaatagcc atgcactcgg atttgaacca aaaggagatg attggtcata
    31981 ttttccatga tgaggatatc ttctaaacca cctctggcac taggataatc agataccctg
    32041 cgaatacgga ttttttcaca catgagcaag tttcctcata tcaatgattt catcagcctt
    32101 attccagact aggggattat gggtcgcaat gatgataatt cgattttcat ctttcaaatc
    32161 caccaagaga ttcataacct cctctgaatt ttcaggatca agagctgctg ttggttcatc
    32221 tgccaaaatc aagggtggat ttttcaaaat agtcttagca agggcaactc gttgggcctc
    32281 tcccccagat aaagtataaa ttttttgttc taaatccaaa taccctagat taactttttc
    32341 taaagccccc acttgccttt ccaaacgttc tacttttgag attttctgac caacaaaacc
    32401 caaatccaaa ttttctttga ttgattggtt ttctaagagg ccaaaatttt gaaagagata
    32461 gcccatctga tctcgaaaat actcacgagt gggaatggtt tttaaatctt tcccctgata
    32521 gagaaccctt cctccatcta tcttttctag ctttcccaag atattcagca gcgtcgtctt
    32581 tccgcttcca ctctttccga ttaaggcata aaccttgccc ttctccagct tgagattcaa
    32641 accagagaaa atcgcgcggt cattaaattt cttttccaat ccttgaatat caatcatctt
    32701 attttccttt caatactgcc atgctaccag cttcttcttt tttgtcctgc cttactaaaa
    32761 tcaagagggc gttaagcgta aacaaagcta caactagagc gctaatcaaa ccatctcttg
    32821 tcaaaatact agataggact aggccaagca agagaactcc tccttgcgcc agtaaatact
    32881 tgccatgaag ctcatagatt gtcataccag caagacgttt aatcataagc tcccgtctga
    32941 actgctcaaa atagagaaga ttcatggaat caaataacaa gatagccgta gacagggtca
    33001 aaatcgtccc aataaggaga gagtaaaact ccacccgttt gtcatttagt accttggcaa
    33061 aaaatagctg gctttttacc aagtaagaaa ccttgtgata cagaccttgc tcttttagag
    33121 ctgtgatgct gtctccatat cgatctagtt tcaaggcact attagccgta gttccccaca
    33181 acatccctgc aacaggtctt gttccagtcg cttgcggcgt tagaactaca ataatcggat
    33241 cttttaggta ctggcgtgtt gtcttgtacc catcattata gaggaaacgt tcctgtcctg
    33301 tttctgtaaa agctagcctt acctgtggga agtagtgttt ctgactcgtc acttctacac
    33361 tttcagatga aaagttttgc aggtaatctg taaacaatcc ttggtagtag gcagactgct
    33421 ctcgcaagct ctcaggcaag atcagcccaa actctccctc agacaagttt tgcatcttgt
    33481 caataaactc tgaagaaacg gtaatctttt cttctatcag atagcgcggc gagacataga
    33541 taacattccc tgacggtatg tagtcactga gacgattgcc atctaggtcc acttctgctc
    33601 catctgagaa attgtcaaca ttgctcataa tataaaaaga gtctgtattg gctaaccgtt
    33661 cttcagtaaa tgtctgccac tcacgattat ccttacgcgt tccttcttca tcggcaaatg
    33721 cactagacca accaaaggat agacggtaac ggtctgagga ctggctccat ttattgctag
    33781 ctctctccat ttcctgcatt tcacggtagt ggggtaggag agctgtcgca ctcgatccga
    33841 ccaccaatac agctaagagt tgccccacca tcatcaatgt catcatccgt ttgagaggga
    33901 gtttcccttt caatagatcc accagactat tttcctgtaa accaagtaga tggacgacac
    33961 ttagtaaggt agaaatccct gccagggtca atccataaag tagaagagca atgatgacca
    34021 gttgtaccgt tgccataaac aaggcacctt gataccagag aatccccaat cccaaaagac
    34081 tggataccag cactgagcag ataagctgtc tcacatcttc taacactggt ctgagagcaa
    34141 ctccaaacaa gctctcacca gctattaagc gaatccctgc ctgacgaagg gatttgatcc
    34201 gataaatcag ggtcagactc ataaaggtca gcagaaaaat agctaaactc agtagcacca
    34261 taggggtggc cgccaatagt aagactatcg aaaatggatc ttctccattc gaaacaaagc
    34321 cttgatagcc aagttctttc aaggtggtct gtaagctcac tccatccaaa cttcctgaca
    34381 caatcaagta agaccctaat aaatcactcg tttctgcact ctccttggag gaaatggtca
    34441 gaccttctgg aagctttccc tcaccataag tggcataggt aaagcgtgtt tctccagctt
    34501 catttggctc aacgattcga cgggcgatga gactattatg ctctaccgcc aagtgactca
    34561 aagcctctgt cacctcttcg cgactagcta ctggttgatt tatcatcatt cctgtcacat
    34621 caacagaagg atagttacca aataaaatct cttctcgatg gtcaacggaa gttatcacca
    34681 tataaagcga taccaatacc attgaaatca aaataaataa acgtttcatc atttcctcca
    34741 aaaagttact tggtcactta gtgagaaggt gaccaagtaa agctaaacaa tagggctata
    34801 ccattctaaa cattatagta gaatgcaact ttctctcccc aagaagtacg aatccatgca
    34861 cgagaagtcc ctccagcacc agcatatccc ttgtcagatg aaccagtttt tctgctaaca
    34921 actgttgaac tatggtattt tgaagggtga tagtagtttg agtaagcacc accgttacct
    34981 gaaccataag tccaaacacc accttctggg tattgaacgg ctgcagaggc aactgctaca
    35041 cttccaccta atgttgctgc aatgctcgct acaagagcta attttttaac tgtttgtttc
    35101 atattgatac tcctctattt ttgattacaa gattgttgag ttacttgctc ctctttccat
    35161 tatcaacgtt gatactatta tattaccaaa tgatattcta aaattatttg tttttctcta
    35221 aattgtcaaa atagcaccct gaaatgaact tttatagtca ttatactcca tctttatcac
    35281 actatcaagg acatcaatgt ccttaaaatc taactatttc atattatttt tagcttatat
    35341 ctaaaaaaac agttctaaag acgaacttta gaactgtttt gatacgagga caaggacatt
    35401 tttgtcactg attcactatg tttataaata tttttttaaa tcttcttgcc attgtttttc
    35461 taacatagta actaaataag aattttctat tatatcagca aatagcttcg atttctgata
    35521 gaactgttcg gcagaaacat aatcattgtt tattattaga gataatttcc actccaacat
    35581 taatataatt ggtttcttct ggaaatcttg tgttttttcc attatatgat taaggctaaa
    35641 gatataagct cctagtgaat cataagacga caagttatcc aaacaggcta gacccgaaaa
    35701 caaagtgtta cttaaagcaa acagatattc tgatgcaatt aattctacat gatttgtcaa
    35761 acgaactaaa aacgaatgaa ttctgttaat ttcttcaatc tgattttgac cttgttttat
    35821 ctttgtaagc actatagcaa aatataagtt gataacttct aattcattta tcaaaaacaa
    35881 ttccttatca taaattgttt taaaataatc gtccagtacg gtttccccgt attctggtcg
    35941 tccacttcga ataacatcta tcgttgctct agtagcttca aaccatactt tttcctcatt
    36001 aggaagttgc tcataaaata aatcctctat ctcttccaaa cacgcttcct tcttatcgta
    36061 ctcctcttct ttaccataga ttggttcacg taaaatctgg tatttcaatt ctaaataagc
    36121 agaaggaaga gctgaaaaat ccggcataag gctataaact ggaactccta gccggcgagc
    36181 aatataggct aacttgggca aactcggttg cgaagctcca ctttcaattc gcgacagttg
    36241 acgaactgtc agttcttgct catctccaca aaaatctgga cgactaattc ctttttctat
    36301 ccgaatctct ttaatttttt gaccaattaa catcagacgc ctcctattct acctgcttcg
    36361 aaaaatactg tgaaacttaa aaaattgtaa cggctacatc tttcctactc ataagatttc
    36421 atagcttctt ccacttctgc caaagtaacc ccaaacaact ctaggcgttt gaggagttgc
    36481 ttgccgttgg aatagccgat tcggagagtc tctccgaggt attctctacg cttacggctg
    36541 tctgcccctg ctagaaaacc aaggcgaatc aaatcgctac gactaatgtc aaactggctc
    36601 tcatgttcaa attgttctgt cacctgagct agagccgttt tcaggtcttc atagctggca
    36661 tgctcaattc ccagagaacg ccccttggtc ttggacttgg gaacagcttc atctcgcttg
    36721 agaaaggcat gctgaactgt tggaatgacc gtcatgatca tgcgccgaat ccgttctcca
    36781 ttaaaatctg ggtctgtaaa gacaatgact ccatgacgtt ggtgcaggcg ctgaatccgc
    36841 tctatatcct gatcattgat ggcagaacct cgagtctcat aggtctccac atcgaaataa
    36901 cgcttgagat tgaccgtatc atcacgccct tcaaccacga taacttgaga aattttctct
    36961 ttcattactt gctgtccagt ccaaaaattc gttctgcatt tgcagtcgtt gctaccgcca
    37021 gctcttctgt cgtcatacca cgcaagtcag cgataaagtc gaccacatag cgagtatagg
    37081 ctgttttatt ttcacgacca cgcttgggta caggtgctaa gtaaggcgca tctgtttcca
    37141 ccaaaatctt gtccaaaagt aactctttag ctgcttcttg gaggtcagtt gccttcttaa
    37201 aagtcaccac tcctgagaag gaaatggtca taccaagatc cacaaacttc tctgcccact
    37261 caagcgtccc tgaaaatgaa tgcatgatac caccacgagg accaacgccc tcactcttga
    37321 taatctcata ggtatcttcc agcgcatcac gggtatggac aacaaaaggc aaatccaagt
    37381 ccttagatag ctgaatctga cggcgaaaaa cctgctcctg cacctctttg ggcgctgtca
    37441 tccaatggta atctaagcca atttcaccta aagccacaac cttgggatgt tttaacttat
    37501 ccaacaagta agcctcaact tcctctgtat aagtaccagc ttctgtagga tgccaaccaa
    37561 tagtcgcata gagctgatca tactcatcta ccaactccaa ggcacgctca atcgtcggtt
    37621 tatcaaaacc aacaatattc atctgtgtca cacccatctc agcagccaag gcaatttctt
    37681 ctgcctcacg acctgcaaat tcttctacat tcaagtgtgt atgtgtatca aaaatcatct
    37741 cttctaacct cgttttctat cttctattat accaaaaaag aggaggggca cctaattttt
    37801 cggtttcccc tcctctcttc aatagagagc tattctgcta tcttttctat ccgatattgc
    37861 ccatctccta ttccacagtt agagacagaa gagattggct acattgatag aatattccta
    37921 ttcagctaaa gtatgtgatt atcttgggtt ctcacttttc tcacccatca ctaggattga
    37981 tgacttctca aaatccccct tataatctaa ctttaagtag agaatagaat tttctagctg
    38041 ttctattttc tacgtctagt ctttcttcct agcaaagcaa aaccacttgt tgccaccact
    38101 agaccaagac tagcaagtgc tgcacttgat gctgaacctg tgttaggtaa ttgtttgcca
    38161 gcaggtgact ggtaggtaac atcttgcatt gttcctgcag ttgcttgcgg tgcacttgtt
    38221 gtcttaggag cagcattagg agccactggt ctcttaggaa ctgtaaccat ggcaatggct
    38281 tgcactccaa tcgtttctgc ttccttcaca tcttccatag ttttcgcatt ttcaatctct
    38341 ttgagagctg cttgtttttc tgcttccact cttgctaaaa gttctgcttt ttctttatca
    38401 gaaagcggtg cgcctttgat ttcatcctgc ttgtccttgg ctgctttttc aatggcattt
    38461 ttagctgatt ctttttcagt agctaattgc ttagaagctt gtgattgagc tgagttttgt
    38521 gaacctgtgt gagctgatcc acccgcctgg ctaccaccgc cttcattcgc attagcatct
    38581 gagcttccag tattgcctcc cttatctcca cctggtgtat tttctagctt atactctggt
    38641 gtagcttctt gagttacaga ttcacctttc gcagattgtt gaactgtatc ttttcctaga
    38701 atcgtcacta ctgaaccatc tgggaatgtg attgttgctg taccatctcc agctacttca
    38761 actttatagt aaaataaaat aataacagga caaatcgatc aggacagtca aatcgatttc
    38821 taacaatgtt ttagaaacag aggtgtacta ttctagtttc aatctactat aacatcgctt
    38881 ccgaatccat ttgcatctac tgaacttttt tacaaaaata aaaatcagta gactcgagtt
    38941 cctactgatt tttgatagaa ttcgtttgga ttatgcagcc aaaactttgc gtcctttacg
    39001 acgacgagct gccaatacgc gacgaccatt tttagttgac atacggttac ggaatccgtg
    39061 tttgcgcgca cgacgaagtt tacttggttg ataagtacgt ttcacgatga atacctcctc
    39121 atagattttg tattcgttta gccggctata aagtgatcag ttactaaaca tactttacta
    39181 ttctatctga ttctttcact tttgtcaata gccctaggca aatgtttcca gctttttcga
    39241 atgcaagccc tatctacgat actgtttcaa gaaacgagtc atcttttctt ggatttgggc
    39301 taactcatca acacgaggaa ggtaaacgat acggaagtgg tctggttcct gccagttaaa
    39361 gcctcgacca tgaaccaaga gaaccttttc ctgcttcaag aaatcaagga caaactgctc
    39421 atcatcatcg atacggtaca tattgcggtc gatttttggg aagatataga gccccgcctt
    39481 gggtttaacg gcagacaaac ctggaatatc ttgaatggca ttatagatga aatttctttg
    39541 ctcgtagatt cgtccaccag gaagaagcaa ttcatcgact gattggtgac cccccaagga
    39601 agtttgtacg acttgttggg ccaaaacgtt agagcaaagg cgcatattgg acagcatatt
    39661 gagcccttcg atatagccct taacatgagt cttagggcca gacaagacca tccaacccac
    39721 acggaaacct gctatgcggt gggattttga cagaccattc atgctgacac agaagacatc
    39781 tggtgccaag ctcgccacag gcgtatgcac atgtccgtcc attaccatgc ggtcatagat
    39841 ttcatccgca aagataatca aatcgttttg acgggcaatc tcaataatct ccagcaagag
    39901 tttcttagga taaagggctc cagttgggtt atttggattg ataaggacga ttgccttggt
    39961 attggaagtg atttttgact tgatatcgtc aatatctggg taccattcaa cagcttcatc
    40021 acagatatag tgaacggcat ttcctccagc taggctgaca gccgccgtcc atagaggata
    40081 gtctggcatt ggcactaaga cctcatcccc attgtccaaa agcccctgca tggacatgac
    40141 aatcaactca ctgacaccat ttccaaggta aatatcatca atatctacgt ttgggaattt
    40201 cttcagctgg caatactgca tgatggcctt acgggctgag aaaattcctt tggagtcaga
    40261 atagccttca ctatcacgcg cattcataat caagtcatga atgacctcgt ctggcgctgt
    40321 aaagccaaat tctgctggat ttcctgtatt cagacgtaaa atcttttctc cattcgctcg
    40381 catccgcatg gcttcttcca atacaggacc acggatatca taagcaacat gctctaactt
    40441 actagacttg ttatattctt tcatcttgtt tcctcaattc atcaggatag taacattata
    40501 ccactagaaa gagaatgcga caagtttact gaaatgtgtt actagtttcg tatagaagaa
    40561 aaaccttgct aaaggcgagg ttaagaacgt agagatagca ggtattttgc aaagacacat
    40621 cacataccaa aagataaacc tagaaaaagc aagcctagaa aggagtcata aagaagatta
    40681 aacatgagga aaagccccca tatcatcaag taatcccaac gcccacttcg ttttgcaact
    40741 agaaataaga ttagatggta gagtacatga aaaactaaaa atccaataaa acttggataa
    40801 agaagcggta ccagactctc taattgacag atcatgatca cttctaccaa gactgaaact
    40861 aggataattc cataataaag gaaatttgat ttttgaaaag agtttttcat cattctccct
    40921 tccttcactt ctttcctgct atcctttctt ttattttatc atatatttat atagagttta
    40981 agccctaata ttcttttgaa aaatactttt tttgctttac ttctatagtg aaaaggttta
    41041 caattatagt aagaaaattt caggaggttt cattatggca caacgttacc aaaatatcat
    41101 ggtcgcaatc gatggttcta aggaagcgga cttggctttt gtcaagggag ttcattctgc
    41161 tctacgaaac gacgctaaac tcaccatcgc acatgtcatt gacacacgcg ctctccaaag
    41221 cgtatccacc tttgatgctg aagtttacga agaactccaa gtcgacgctg aaagtctgat
    41281 gaaagagtac gaaaaacgtg ctaaagatgc tggggtagca gatgttcata tcgtcattga
    41341 aatgggaaat ccaaagaccc tgctagcacg tactattcca gatgccgagg aagtggacct
    41401 catcctcgtt ggcgcaactg gtctcaacgc ctttgaacgc ctcttggtcg gctcttcatc
    41461 tgaatacata ctccgccatg ctaaggtcga tttgctggtt gtgagagaac aagaaaaaac
    41521 cttataatca caaagaaaag gagcccctag ctcctttttg tttacgattt atttctctct
    41581 ttatggcgtt cgtaagcctt gagctggcgc tgcagttcct ttttaatagc aggttctgga
    41641 gcatattttt cttcccaatt atctggtttt aagattttat gggtcactgg atcaaaatga
    41701 gccttgccat ctggaaaaat tttccccata ttggcctgat ggacaatatc aaaaatacgt
    41761 tctgggtcca cccccatcaa gacaaaactg ccgtaggtga agtaaagcgt gtcaatcaag
    41821 gcatccactt gccctatcaa atcttgctga gcaggtgtct tcttggctac tttatctgct
    41881 gccttatcaa gggcctgatg aagttgcgat acagcttgac caaaatcttc ttcagaagga
    41941 ctggctgctc gaacaaactc caccaattct tctattttaa aaccagccct atgggttgca
    42001 ccctctaaat cccaagctcg aggttcttct tgggttcgtt catccatcat gtggtggaag
    42061 gtcttgacct tattgaaatg atagtcacgg ctgacaaaga ctttttctga agacaaaaca
    42121 ccaaaatgtt ccaaggcctt gtggatccca tcttgttgat tgctagtggt aatgtgcttg
    42181 gcagcttcct tgacactgct actaccattt cccatagcga ccgacatacc gacgccagcc
    42241 agcatttcaa ggtcattatc tgagtcacca aaagccatga cttgattgag gtcaaagcca
    42301 tattctttcc caactcggcg aatgccttct aatttagaat ttccctgatt gatgacatcc
    42361 gatgcaaaag gattgctacg tgtcaatttc aagtcttcaa aatcagctgc cgccttctca
    42421 gattcttctg gtgtcatcag catcaaaact tggtagatag gctgattcat caggtgaagc
    42481 aggtcctctt ccttttgggg aacaaccttg ctgaccatgc gattaaaaga ctgactcacc
    42541 gtccgagtta aaacagaggg aacgaagcga ctaattcgtt gggaaaaaga acccagacca
    42601 aaggacatga ttttagaacc caacatggca tccttggtcc ctagggcaat ctccgtgccc
    42661 tcttttttag catagctaat tagatggcgc aaatgtaact tggaaatagg gctcgtgaac
    42721 aagactctgt ctttactaaa gatatactgg ccattatagg ttaccgcaaa atccagatcc
    42781 aaatcgtcca tcaattcctt aacaaaaaaa ggtcctcgcc ctgtcgctac gccaactagt
    42841 accccttgtt ctttgacaat cttaatcgca tccttagtgg atttcaaaac actcttgcga
    42901 ttgttgacca aggttccatc gatatcaaaa aaaacagctt tgacttccat cctatcccaa
    42961 tctccccttt tgtgatacaa tgattatacc acatttcaga aagagttagt aaatcatgcc
    43021 taagaaaatc cttgttttac atacgggtgg aactatttcc atgcaggccg atgcttctgg
    43081 cgctgttgtg acgagttcag ataatcccat gaaccatgtg tccaacccac ttgaaggaat
    43141 ccaagtccac gccttggact tttttaacct tccaagtccc catatcaaac ccaaacatat
    43201 gctggtcctc taccagaaaa ttaaagagga agcagataac tacgatggag tggtgatcac
    43261 acacggaacc gatactttag aggaaacagc ctatttcctt gataccatgg aagttcccca
    43321 tatgcctatc gttctaacag gagccatgcg tagctccaat gagctcggta gtgatggtgt
    43381 ttataattac ctaagtgctt tacgagtggc cagtgatgac agggctgctg acaaaggagt
    43441 tttggtcgtt atgaacgatg aaatccacgc tgccaagtat gtcaccaaaa cacatacgac
    43501 taatgtcaac accttccaga ctccaacaca tggccccctc ggtctcatca tgaaacagga
    43561 aatcctctac ttcaaaacag ctgaacctcg tgttcgcttt gaccttgatc acatacaagg
    43621 tttagtccct atcatctcgg cttatgctgg tatgacagat gagctgattg atatgctgga
    43681 tttagaacac ttggacggtt tgattatcca agccttcgga gctggtaata ttcccaaaga
    43741 aacggctcaa aaattagaaa gccttctgca aaaaggaatc ccagtcgctc tggtatcacg
    43801 atgctttaac ggtattgccg agcctgttta tgcctaccag ggtgggggcg tacagttgca
    43861 aaaagcaggc gttttctttg ttaaagaact caacgcccaa aaagcccgct tgaaactcct
    43921 catcgccctc aatgccggac taacaggaca ggctttgaaa gactatatgg aaggctaata
    43981 ctcttcgaaa atctctgcaa accacgtcac gtcgccttac cgtatgtatg gttactgact
    44041 tcgtcagttc tatctacaac ctcaaaaaca tgttttgagc tgacttcgtc agttctatct
    44101 acaacctcaa agcagtgctt tgagctgact tcgtcagttc tatctgcaac ctcaaaacag
    44161 tgtgttgcac agcctttaac cagccgccta gtccgctcta tggtattcat taagtcaaca
    44221 tctcttgttt aagagcacaa aatcaggaaa tcttctcgat tccctgattt tttctattta
    44281 cgttttcgtg ttgagctacg ttctgtcaaa ccatgaggta agagaacttc acgttcttcc
    44341 aactcttcct tatgcataat cttggtcaac atacgcatac taatggcacc aaggtcataa
    44401 agaggttggg caatcgttgt caagtttgga cgggtaaagc gtgagatttg tgaatcatca
    44461 ctagtaataa tttcaaaatc ttctggcaca gaaacaccct tatcagccaa accgttcaag
    44521 actcctgctg ccaactcatc acctgtcaca actgctgcag ttgcatttga tgaaatcaaa
    44581 cgctctgcta aggcgtaacc atcatcatag ctatatttag attcaaatac caaaccctca
    44641 ctataagcga ttcctgcttt tttcaaggtt tccttgtagc caactaaacg aaccttacca
    44701 ttgatgtcat ccactagcgg accgctaacg aaagcaatac gctcattttc tttagcaagg
    44761 taactcactg catcaattgt tgcttgctta tagtcaatat tgacacttgg caactggtgc
    44821 tcaacatcga cagttcctgc gagaacaatc ggagtacgtg aacgcgaaaa ttctgagcga
    44881 attttatctg tcaagtgata acccatatag ataatgccat ctacctgctt tgaaaagagg
    44941 gtattgacaa cagaaacttc tttctcgtta tcttcatcgc tattagctag gacaatattg
    45001 tacttgtaca tttctgcaat atcatcaatc cccttagcca aactcgaaaa ataaccattg
    45061 gtaatatttg gaatcacgac accgacagtg gttgtctttt tacttgcaag accacgcgca
    45121 actgcatttg gacgataatc caaacgatca attacctcta gcactttttt acgggtattc
    45181 tcttttacat ttttattgcc attgaccaca cggctgaccg tcgccatgga aacacctgct
    45241 tcacgagcga catcataaat ggttactgta tcatctgcat tcattccttt tcctgtcctt
    45301 tctatctcac acattctttt acaagtagag gtactgattg aagctctata tctacttaca
    45361 aaagtgaaga tgtgaaaatt tcgttttcat atttctactt attccattct atcactaatt
    45421 gtaaacactt tcaagtgttt tttgaagatt gattgaaaaa atttcataga aaacctaggt
    45481 ttagctcctt gctaccacct tagactaaac aaaaaggagg aaactaagcc ctcctaaagt
    45541 tatagtaaaa tgaaataaga acaggataaa tcgatcagga cagtcaaatc gatttctaac
    45601 aatgttttag aagtagaggt gtactattct agtttccatc tactataggt attgttccat
    45661 tcactaccgt caattttagc acatagtctt catgaaaata ttatatcatc ataaccaacc
    45721 agattctttt gcgatattag ctgcctctgt tcgattacca gcatccagtt ttgaaagaat
    45781 attggtgaca tagtttcgaa tagttccgtt tgagaggtaa agctgatctg cgatttcttg
    45841 gttggataag ccccgggcga ttccctttaa gacagcaatc tcttgttctg tcaacggatt
    45901 gggacgggtc atcaccactt ccatcaattc aggcgaatac tccttgcgtc cttcgaggac
    45961 ggtgtgcaag gtttgcatga ggtctgcaat gcttcgttcc tttaatacat aagcatccac
    46021 tccagccttg accgcacgtt caaaataccc agcacgcttg aaggtcgtca ccacaaccac
    46081 ctttgtttca agcctttctg atcgtatcca ctccaagact tcaagacctg tcttaacagg
    46141 catttctacg tcaaggatgg tgatatctac agactccttt tctaatagtt ggattgcttc
    46201 ttgcccattt ttggcttgaa ggacagactc cacatctggt tgaagcgtga gcaattgaca
    46261 catggcatct cgcaacatac tttgatcttc tgcgactaat actttcatct tagtttctct
    46321 ccttataagg tagtcgaact tgcacttccg ttggatgttt ctgactgatt acacttactt
    46381 ctcctgaaaa tggaaaaaca cgttctcgga ctgtatggag ctcatctcct tttagaaaag
    46441 caaagccgca gccatcatca cttactgtta aaatgagttc cttctctgtc cgttctaatt
    46501 ttaagtaagc tttagacgct ttggcatgtt tgatgatatt ggtcaccaac tcaagcaaaa
    46561 tcatagaagc cattgactcc aattcttgag taaggctagc agtatctagt tggttatctg
    46621 tttccacctc aattccagca atttctaaca tctttttcac agtctctagt tcggatgtca
    46681 aagttctaga cttaagattt tccacaatgg ttcgaacttc acgcattgat tctttgctaa
    46741 tttgctgtat ttctcttaat tccttttcca cttgtggata agcctgcatt tgaaatagct
    46801 gcaaggctag atctgtcttg acactaagca tagcaaaggt atgtcccaga ctatcatgca
    46861 aatcctgacc gatacgattg cgctcatttt ctgctagcaa tagatttatc tgggtatttt
    46921 gcttgacctg agcttctttc aaatcctcga caaggcgaat tcgaaccgag cccaaagtca
    46981 tcaaatcgac aaaagtaaga attacaagca tatagactag aaactcaact tcgattctct
    47041 gaaaaatcaa aagtcgcccc acaacaagga cttgagcaag gagaaatgtc catacatgta
    47101 aagactttaa actacgtacg ccaaaatgat aaattaagag attggaaagg aaaaataaaa
    47161 accagatata attcccagca acaaagacgg tattcccagc tacatagacc agcatgatcc
    47221 cccagaaaag ccaagatagg cgctggttct tagttattaa aacacccaaa tacgtcacta
    47281 caaatagaat atcaaccaat aaatgccaag caggaagctc cccaatcact acaggtagga
    47341 tgggaaaaag cataaaaatc aaactggcac aaaacatata gtgtatgctt ttcagtcttt
    47401 caagcattaa gcattctcct tatgaccttg aaggtaaata gtcaaaccaa ataaaactgc
    47461 tgaaaaaaca agtaaataaa ctgtggctga tagattgatg ccaccctcgt ttaagaaggt
    47521 cttgagcaac tccatcaact gataagttgg gagacactta ccgatcgctt gcatccagtc
    47581 tggaaataaa gagataggca tccagagtcc gcctaaaaca gccaatccta gataaagaag
    47641 attgcccaca acagacatca gctgactagt tggtaagaga gtcaaggtca agccaagggc
    47701 tacaaaagct acacttccca aaataagcaa aatcgcagcc ccaacccagc ttcctagagg
    47761 aatctctaca cctcttacaa agtgcccaac tgagaaaacc accaagattg aaaccaaata
    47821 atcaaccagc atacttgtta tctttgatag ataatattct accatattta cagggctatg
    47881 acgtaatgtt ttctgccagt tgttgatttt atctgtatgt aaaacagctg ggaatgaaaa
    47941 catagctgtc gacatcatgg aaaaggctgt catggagatg aggtaatcac gcataaaatt
    48001 agctggtcca cctggtgtct cctggtagat gccagaaaag aataaataga aagccgtcgg
    48061 cattcctacg gataataaat aatagacgag ttgccgtttg gtcaataaaa attctatctt
    48121 atttaatgct atccatcgtt tcatcttagt catctccttt ttgcgtttct tcaaagattg
    48181 tatccagcaa actacgatta ttaacttcga tttcttgcat cctacatcct gcttgggcta
    48241 atagttccca gaaagcatct gcttctcgag tgactacttg taaagaatct tgctttaggg
    48301 tccagttttc aaccaaattt gactgctcta cgacttcctt gtaagctata ggaaggataa
    48361 agtgcttttc tatttcctcg ctacgcatag ctagaggcgt cgtatctcga atcaactctc
    48421 ccttatttaa gagcaaaatg cggtctgcag tgtgttccac ttcctcaata taatgggacg
    48481 aatagagaat ggtgactcct tgcgctttta actcctggac aatttcccaa aaacgttgac
    48541 gagttgaggt atccatggac gcagtaggct catctaaaaa aacaatcttt ggtcgcccaa
    48601 ttaaggtcaa gacgaaagaa aagagacgct tttgaccgcc tgataatttt tctgccaact
    48661 gttctttttg ttgcttgaca aactgcaata gttgatcaat ttcctgattg ctcaaaggat
    48721 ttggatagat acgttgaaag aaagcaatca actctttaac ttttaatttc tgaacgatta
    48781 cattttcttg agggaggtaa gccctagtat agtctaactt agaactcgtc actggtaaac
    48841 cttgaataga tacttgaccg cttgtgacca gtttatctcc aagcaaacaa tctaagagtg
    48901 ttgtctttcc ggcaccattt ggaccaatta aggcaacaca ttcaccatcg ttgatttcaa
    48961 aggagatatt ccgcaaaatt tccttgtctt ttattttctt actcaatttc tcaactttaa
    49021 ccaccgtcat gagactctcc tttcaaccac tccattccca taaggaaaac gacgaaaatc
    49081 ataaatccaa accccaaagc accacgaatg aattggcgaa gcaaggcttg atcaaaccaa
    49141 tcagtaaaca tttccactaa ccataccaag agtgacaggc cgataaagaa atagatgatc
    49201 cctctcttca ttcctcaaac tcctttttca catctctgac taatttcaaa ccttctctaa
    49261 caagccaaga catgattcca aagccagcaa agaccttcca aggaaaatgg tagaaatcct
    49321 catccaatcc cgaaaacatg agataggtca taactcctgc tactactaaa cttactgcga
    49381 taatcatttt atttctcatc tcttcttccc ccatttcata ctacaattat agtcttttaa
    49441 aatcagagga gacagaagct tctgtcacta gaaaatatga caaatgtcat aaaaaattct
    49501 gttcaaaaca agcaagatac actatacaat aaaacacaat cagaaaaatc taaggcaact
    49561 tcctcaaaag agatatcaaa cccaattcac accataatgt aaactaatac ttatttaaaa
    49621 tcaaaaagag taaaaatttt tatcagacaa acacatatat agtgtattga atctataaca
    49681 gtaggcctta aatactaaaa tatttctata aattaattta actttcctga tagaactgtt
    49741 catatcttat ttcaattctc tatattatac gttgaaccaa acccttctat tgctttctta
    49801 aaaatttata agagttataa aatctgttaa atttcaatgt gtatacctaa actacggtat
    49861 ttattgaaaa aactggagac aaaaagtata cgttgccaaa atgaattact gaaaatcaaa
    49921 aaagagagga ccaaactgat tccctcttaa tgtatataat atctagtttt aaaaatacac
    49981 actcacatat ctctgt
//
LOCUS       DBJKQU010000009        45464 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.009, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000009 DBJKQU010000000
VERSION     DBJKQU010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45464
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.009"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            204..509
                     /locus_tag="ACSUUC_000608"
                     /pseudo
     CDS             204..509
                     /locus_tag="ACSUUC_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            641..1585
                     /gene="manA"
                     /locus_tag="ACSUUC_000609"
     CDS             641..1585
                     /gene="manA"
                     /locus_tag="ACSUUC_000609"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HHQ8053880.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGIFILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1606..3084)
                     /locus_tag="ACSUUC_000610"
     CDS             complement(1606..3084)
                     /locus_tag="ACSUUC_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HHQ8053881.1"
                     /translation="MIFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSAIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFEKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSLWSSLPNLCNQKGLE"
     gene            3189..3938
                     /locus_tag="ACSUUC_000611"
     CDS             3189..3938
                     /locus_tag="ACSUUC_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHQ8053882.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLYTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(3958..4413)
                     /locus_tag="ACSUUC_000612"
     CDS             complement(3958..4413)
                     /locus_tag="ACSUUC_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HHQ8053883.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4433..5607)
                     /locus_tag="ACSUUC_000613"
                     /pseudo
     CDS             complement(4433..5607)
                     /locus_tag="ACSUUC_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
     gene            complement(5666..6511)
                     /locus_tag="ACSUUC_000614"
     CDS             complement(5666..6511)
                     /locus_tag="ACSUUC_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HHQ8053884.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSIQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            6636..7193
                     /locus_tag="ACSUUC_000615"
     CDS             6636..7193
                     /locus_tag="ACSUUC_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHQ8053885.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7212..7679
                     /locus_tag="ACSUUC_000616"
     CDS             7212..7679
                     /locus_tag="ACSUUC_000616"
                     /EC_number="3.5.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004132 - dCMP deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006220 - pyrimidine nucleotide metabolic
                     process [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxycytidylate deaminase"
                     /protein_id="HHQ8053886.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7768..8397
                     /gene="upp"
                     /locus_tag="ACSUUC_000617"
     CDS             7768..8397
                     /gene="upp"
                     /locus_tag="ACSUUC_000617"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HHQ8053887.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8571..9161
                     /gene="clpP"
                     /locus_tag="ACSUUC_000618"
     CDS             8571..9161
                     /gene="clpP"
                     /locus_tag="ACSUUC_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HHQ8053888.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9240..9488
                     /locus_tag="ACSUUC_000619"
     CDS             9240..9488
                     /locus_tag="ACSUUC_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HHQ8053889.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9590..10750
                     /locus_tag="ACSUUC_000620"
     CDS             9590..10750
                     /locus_tag="ACSUUC_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHQ8053890.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINGAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            11018..11887
                     /locus_tag="ACSUUC_000621"
     CDS             11018..11887
                     /locus_tag="ACSUUC_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HHQ8053891.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11891..12847
                     /locus_tag="ACSUUC_000622"
     CDS             11891..12847
                     /locus_tag="ACSUUC_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HHQ8053892.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12847..13611
                     /locus_tag="ACSUUC_000623"
     CDS             12847..13611
                     /locus_tag="ACSUUC_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053893.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13611..14321
                     /locus_tag="ACSUUC_000624"
     CDS             13611..14321
                     /locus_tag="ACSUUC_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053894.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14629..15285
                     /locus_tag="ACSUUC_000625"
     CDS             14629..15285
                     /locus_tag="ACSUUC_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HHQ8053895.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15392..16487
                     /gene="prfB"
                     /locus_tag="ACSUUC_000626"
     CDS             join(15392..15463,15465..16487)
                     /gene="prfB"
                     /locus_tag="ACSUUC_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HHQ8053896.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16505..17197
                     /gene="ftsE"
                     /locus_tag="ACSUUC_000627"
     CDS             16505..17197
                     /gene="ftsE"
                     /locus_tag="ACSUUC_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HHQ8053897.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17190..18116
                     /gene="ftsX"
                     /locus_tag="ACSUUC_000628"
     CDS             17190..18116
                     /gene="ftsX"
                     /locus_tag="ACSUUC_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HHQ8053898.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSAVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18384..20564
                     /locus_tag="ACSUUC_000629"
     CDS             18384..20564
                     /locus_tag="ACSUUC_000629"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HHQ8053899.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20616..21431
                     /locus_tag="ACSUUC_000630"
     CDS             20616..21431
                     /locus_tag="ACSUUC_000630"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HHQ8053900.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            21571..22914
                     /locus_tag="ACSUUC_000631"
     CDS             21571..22914
                     /locus_tag="ACSUUC_000631"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HHQ8053901.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLEIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23129..24319
                     /gene="metK"
                     /locus_tag="ACSUUC_000632"
     CDS             23129..24319
                     /gene="metK"
                     /locus_tag="ACSUUC_000632"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HHQ8053902.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24754..25689
                     /locus_tag="ACSUUC_000633"
     CDS             24754..25689
                     /locus_tag="ACSUUC_000633"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HHQ8053903.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIKELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25723..26760
                     /gene="holA"
                     /locus_tag="ACSUUC_000634"
     CDS             25723..26760
                     /gene="holA"
                     /locus_tag="ACSUUC_000634"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HHQ8053904.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKVDSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            26933..27538
                     /gene="sodA"
                     /locus_tag="ACSUUC_000635"
     CDS             26933..27538
                     /gene="sodA"
                     /locus_tag="ACSUUC_000635"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HHQ8053905.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27695..28225
                     /locus_tag="ACSUUC_000636"
     CDS             27695..28225
                     /locus_tag="ACSUUC_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HHQ8053906.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISCLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SHKEDKGQRHFVIRQK"
     gene            28246..29331
                     /gene="rlmN"
                     /locus_tag="ACSUUC_000637"
     CDS             28246..29331
                     /gene="rlmN"
                     /locus_tag="ACSUUC_000637"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HHQ8053907.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVDCNIGCTFCASDLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFVCTINDDKGMAIGARHITVSTSGLAHKIRNFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEYGT
                     DIDAACGQLRSNTMKRDRQKAVAEVNP"
     gene            29333..29806
                     /locus_tag="ACSUUC_000638"
     CDS             29333..29806
                     /locus_tag="ACSUUC_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HHQ8053908.1"
                     /translation="MTKKRELILRLGVAVYSLCIVYFCFTPQATVEVGTPGIQHLGRL
                     VFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKKVLL
                     FSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN"
     gene            29808..31349
                     /locus_tag="ACSUUC_000639"
     CDS             29808..31349
                     /locus_tag="ACSUUC_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HHQ8053909.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMTEDGADVDALMEEVGELQDRLESRDFYILDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKSLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31405..32208)
                     /locus_tag="ACSUUC_000640"
     CDS             complement(31405..32208)
                     /locus_tag="ACSUUC_000640"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HHQ8053910.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNHALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32291..32503)
                     /locus_tag="ACSUUC_000641"
     CDS             complement(32291..32503)
                     /locus_tag="ACSUUC_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053911.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            complement(32983..33192)
                     /locus_tag="ACSUUC_000642"
     CDS             complement(32983..33192)
                     /locus_tag="ACSUUC_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053912.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            33362..33634
                     /gene="rpsP"
                     /locus_tag="ACSUUC_000643"
     CDS             33362..33634
                     /gene="rpsP"
                     /locus_tag="ACSUUC_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HHQ8053913.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33654..33893
                     /gene="kphA"
                     /locus_tag="ACSUUC_000644"
     CDS             33654..33893
                     /gene="kphA"
                     /locus_tag="ACSUUC_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HHQ8053914.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            34054..34366
                     /locus_tag="ACSUUC_000645"
                     /pseudo
     CDS             34054..34366
                     /locus_tag="ACSUUC_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
     gene            34470..35258
                     /locus_tag="ACSUUC_000646"
     CDS             34470..35258
                     /locus_tag="ACSUUC_000646"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHQ8053915.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            35289..35807
                     /gene="rimM"
                     /locus_tag="ACSUUC_000647"
     CDS             35289..35807
                     /gene="rimM"
                     /locus_tag="ACSUUC_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HHQ8053916.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            35797..36516
                     /gene="trmD"
                     /locus_tag="ACSUUC_000648"
     CDS             35797..36516
                     /gene="trmD"
                     /locus_tag="ACSUUC_000648"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HHQ8053917.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            36528..36866
                     /locus_tag="ACSUUC_000649"
     CDS             36528..36866
                     /locus_tag="ACSUUC_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HHQ8053918.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(36896..37216)
                     /locus_tag="ACSUUC_000650"
     CDS             complement(36896..37216)
                     /locus_tag="ACSUUC_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053919.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            37314..37529
                     /locus_tag="ACSUUC_000651"
     CDS             37314..37529
                     /locus_tag="ACSUUC_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HHQ8053920.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(37526..37714)
                     /locus_tag="ACSUUC_000652"
     CDS             complement(37526..37714)
                     /locus_tag="ACSUUC_000652"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053921.1"
                     /translation="MTQYPFFYFENLYSMKIKEQTRKLAAGCSKHCFEVVDETDEVSN
                     HTYGKAKLMRFEEIFEEY"
     gene            complement(37734..38270)
                     /locus_tag="ACSUUC_000653"
     CDS             complement(37734..38270)
                     /locus_tag="ACSUUC_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HHQ8053922.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQTYFTN"
     gene            complement(38466..39812)
                     /gene="gor"
                     /locus_tag="ACSUUC_000654"
     CDS             complement(38466..39812)
                     /gene="gor"
                     /locus_tag="ACSUUC_000654"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HHQ8053923.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            40098..41297
                     /locus_tag="ACSUUC_000655"
     CDS             40098..41297
                     /locus_tag="ACSUUC_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HHQ8053924.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVANEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            41281..41982
                     /locus_tag="ACSUUC_000656"
     CDS             41281..41982
                     /locus_tag="ACSUUC_000656"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8053925.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            41984..43243
                     /locus_tag="ACSUUC_000657"
     CDS             41984..43243
                     /locus_tag="ACSUUC_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8053926.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            43367..45364
                     /gene="metG"
                     /locus_tag="ACSUUC_000658"
     CDS             43367..45364
                     /gene="metG"
                     /locus_tag="ACSUUC_000658"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HHQ8053927.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFCLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT        13911 a         8416 c         9912 g        13225 t
ORIGIN      
        1 ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgccct gttcttgttt
       61 cgttttacta tagaacgatt tgaaggcgtt tatgatattt agctgtacga gagtctttaa
      121 aaagtgtttt gatggtttgg atttcttctt tagttgattt catatcacta ttatataatg
      181 ctttttgatt ttagtatagt attatcgtag aaaatggact cggtgctatg gatacaccgg
      241 atgagaatgg ttatgtagca gatgactatc ggattactta cttagaggcc cacatcaagg
      301 ccatgcgaga tgccatttac aaagacgggg ttgacttgct tggttatacg acatggggct
      361 gtatcgattc ggtttcagct ggcacagggg aaatgaataa gcgctatggc tttatctatg
      421 tagatcgaga taatgtagga aatgggactc tcaaacgtag caagaagaag tccttctatt
      481 ggtacatgtc atttatagca atggtgtaag catcgagtag agcacatttg tttactattt
      541 ttataaaatc ttctccctgc tttataagat gtaaaaaaga gttcaattcg aactcttttt
      601 ttgctataat gaggggagaa aaatcagaca ggagatcgac atgtcagaac cattattttt
      661 acaatcagtt atgcaagaaa aaatctgggg tggagccaag ctacgtgatg agtttggcta
      721 cgacatccca agtgaaaaaa tcggagaata ttgggccatc tcagcccatc caaatggagt
      781 ctctaaagtt gccaatggtc gttacgaggg aacagatctt gctactttgt atgcggaaca
      841 ccgtgaatta tttggcaatc gtccagaacc tgtatttcca cttttgacca agatcctcga
      901 tgccaacgac tggctcagtg tccaagttca cccagacgat gcttatggac tcgagcatga
      961 aggcgaactc ggaaaaacag aatgctggta cattatcgca gcggatgaag gttcagagat
     1021 tatctacggt cacaatgcca agtcaaaaga agaactccgc cagcaaatcg aggacaagaa
     1081 ctgggatgac ttgttgacca aagtccctgt taaggctgga gatttcttct atgtaccaag
     1141 cgggactatg cacgctatcg gggcgggtat cttcatcctt gaaacccagc agtctagcga
     1201 taccacctat cgcgtctatg actttgaccg caaggatgac aaaggcaact tgcgtgaact
     1261 tcatcttgaa aaatccatcg atgtcttgaa cattggtgag ccagcaaata gccgtcctgt
     1321 aactgttaaa gcagatgatt tgcgttccac tctccttgta tctaatgatt tcttcgcagt
     1381 ttacaagtgg gaaattactg gaaaagttga ctttgaaaag acagctgact acagcttatt
     1441 gagtgtctta gctggtcaag gtcagctaac tgttgacggg aaaaattatc caattcaaaa
     1501 aggcagccac tttatcctac caagtgatgt tgaagcttgg actctggaag ggcaaggttt
     1561 ggaattgatt gttagccatc cataaaaaga aagggcctga gttcactact caagtccttt
     1621 ttgattacat aaattgggca atgaagacca caatgatgat gattggaatg acggaacgaa
     1681 gaaacgaaga aggaagagcc agacttggaa cagtccttgt ttccatgctc tttcatcgag
     1741 atggagttcc tccattgcaa gagccttttt aaagatatag cctgtaaaaa gtgaaaggta
     1801 gagagctcca aatggcatga ggagattgga aaccaagaag tccatagcgt caaagaaggt
     1861 cttaccaaaa atgtgaacat ccgccatgac accgtaagat agggctgaag gaatgccaaa
     1921 gacaaaggtc aaaattccta aaataacact ccatttggca cgtttgctgt tatcctggtt
     1981 ggtgatattg cccacattga tctccagcat cacgacagaa gaagtgacag tcgcaaagag
     2041 gaagaggacg tagaaaatgg ttccaaaagg catcttgtca aagagttgag gcaagacgat
     2101 aaagagcagg ctgggtcccc cttcagactg gatattgaag ggggatcgag cttggaaaat
     2161 ggctagacct gccatgatgg atatcgagat attcatggct acgatggaga ttcctgactg
     2221 gactagattg gttttcttgt ccaagtaaga agcataggtc aacatgactg taacccctag
     2281 tgagagggca aagaaagatt gtcccagagc atagaggaga ccagcgctag tcagttttga
     2341 aaagtctggt ttgaggaagt aaagaacccc ttccatggca tttggcaaac tgagagagcg
     2401 accgatgata acaacaaaga tgataaagag caggggcatc atgactttcg aagctctttc
     2461 aatccctttt tgaaccccac gtgatacaat gaagatattc aataggataa aggccgcttg
     2521 agctcctagg gcaatggctg gatttgaaat gattgaagta aataactgag cataatcacc
     2581 cgttccacca agttggaaca atttcccaaa ctcaatacct agatagacta gaatccatcc
     2641 tccgataaca ctgtaaaaag ataagaggat aaagagggca aaggcgccaa tccaaccgat
     2701 aaagttgtac ttgttattct tgcccagttt ttcaaaggtt ttgatagcgg aaacgccagc
     2761 actacggcca agggcaaact cagccagcag gagagggaaa ccgattaaaa tagtggaaat
     2821 gagaaagatt agtaaaaagc ctccaccgcc attagcagca gtcatgtagg gaaacttcca
     2881 aacggaacca agcccgatgg ccgagccagc agatgctaga ataaaaccaa gtttcgaccc
     2941 ccattgtgat ttttctgaca tagttaaact ctgatctcct ttttcaaaat aagaaaaagc
     3001 tacttgagtt gtcaaatagc cttctgtttg attgatagac ttgactatcc tatcatgttt
     3061 tctaaggtct gtcaagaaaa tcattttcaa gttttcatac ctttctcaaa aaagttaaaa
     3121 aattttctca aaaacgcttg actctgacct aaggggaggg gttatactat cattgtaagg
     3181 aggaaatcat gtaccatata aaagaagctg cgcagctttc aggtgtctct gtcaagaccc
     3241 tgcatcacta tgacaagata ggactcttgg tccccttaaa gtcggaaaac ggctatcgaa
     3301 cctacagtca agaggatttg gaacgccttc aggtcattct ttactacaaa tatctaggct
     3361 tttctttaga gaaaatagca gagctgttaa aggaagaaag gacagattta ttgccccatt
     3421 tgactaggca gttggactat ctaactcgcg aaaggcaaca tctgtatacc ttgatttcca
     3481 ccttgcaaaa aactattcaa gaacaaaaag gagaaagaaa aatgaccatt gaggaaaaat
     3541 tcacgggatt tagctatcaa gacaatcaaa aataccacca agaagcggta gagaaatatg
     3601 gtcaagaagt catgggacaa gcgctcgaac gccaaaaagg tcacgaagac gaggctacgg
     3661 ccgcctttaa ccaagtcttt caaactttgg cacaaaatct tcaagttggt ttacctgcaa
     3721 cagcaaccga aaaccaagag caagcagcca agctcttgca agccattcgc acttatggat
     3781 ttgactgctc tattgaggta ttcggtcata tcggtaaagg ttacgtctac aacccagagt
     3841 ttaaggaaaa cattgacaag tttggttctg gaacagccca gtacacgtca gatgccattg
     3901 cagcttacgt tcagacaaat gcagaaaaaa taggctagga atttcctagc ctatttttta
     3961 cttcaaatca taaagccagt cgtcaccgtt tttgtagtaa aagaattcac tgagatcttc
     4021 ttctagaaac acacgaagca tatcagacat atcatcggtt gcaagtttta gatgagaaag
     4081 attttcaaag tcctcccacc aaactttccc ttcgtctgaa gactggagtt caccagtaaa
     4141 gtgttctgtc ttgtaaaaaa ggacgacata acgataatcc ttgtcgtcat accagttttt
     4201 gataccacag agttggggtt tggaaatgat cagaccagtt tcttctttca cttcacgaat
     4261 gacagcatcg acaaaggatt cgccacgttc aacatgacca ccaggaaaag taatgccagg
     4321 ccagtcggga ctaactcggt cttggaccag gaccttatct ccgtttttaa tcatacacat
     4381 gttaacaaat tcgactgcct ctcttctgtt cattcttcac aacctttaat ctttaatcat
     4441 aatgcagact tcccgccacc cagccggtac agagggcaga agtgatgtta aagccacccg
     4501 tgtgggcatt gatatccata acttcgcctg caaagtggag gccaggtacc agcttacttt
     4561 caagggtttt aggattgatt tccttgagac tgactccacc cttggtaaca aaggactttg
     4621 caagggacat ttttccagtt acaggaattt taagttcttt aatggactgg acaagctgtt
     4681 ctcgttcctt ttcagtcagc tgtttgactt tttcaggata tccttgtaca aaaaattcgg
     4741 ccaagcgttc tggtaacaag gtttttaaag cgtttttcaa ggatttttcc cgattttttc
     4801 tagaaatgta accaagttct tctcagaaag ttgaggcaaa acatcgagtg agagaacctc
     4861 cccaccgttt acaaagctag acatgcgtag ggcagcagga cctgacaaac caaagtgggt
     4921 aaagagtaaa tcatgagtga tgacatgctt accataactt agggtcacat cgtccagaga
     4981 aatcccttgt aaggctttat gtggaaaatc tgttaataaa ggactttcag cagcctcaag
     5041 atctgtgatg gtatgcttaa aatggcgagc aatctcgtga ccaaaaccag tcgaaccagt
     5101 cgaaggataa gacttaccac ctgttgtgac aatgagtttc tcacaagtga aggtttgatc
     5161 cgctgactta aggacaaact ggtcatctac ttttttaaca gaaacgattt ctatttgagt
     5221 agcaacttga ccacctagtt cggtgatttt cttttccaaa gcttcgataa tagtccgaga
     5281 cttgtcactg gctggaaaga cgcgtccgtg gtcttcgacc ttaagtttaa caccattttc
     5341 tgtaaaaaag ttgatgatgt catgattatc gaactgggag aaaacactgt aaagaaagcg
     5401 tccgtttcca ggaattccag ctagcaggtt gtctaagcta ccattgttgg tcacattgca
     5461 acgtccccca ccagtcccag ctaatttttt tccaagtttc cgattttttt cgatgaggag
     5521 ggttttctgt ccataaaagc tactggaaat cgtagccatc ataccagcag gtcccccacc
     5581 gatgacaata gtatcaaaat gtttcatagc tctattgtac cacaaaaaaa caagagatga
     5641 tggtcacctc ttgtcaagaa tgcaattaat caatttcata gcccatcagc aaaccgccat
     5701 cttctgcata gaaactgcag agaccagagg ttggtagaat tttaatatcc gcttgtggga
     5761 aggtttcacg gattcgctct gagagctgtt gacaacattt ttcgttattg cgttgggcca
     5821 tgacaatacg gccaccagca tatccagctt ttactaactc atcataggca gcttgaattg
     5881 atttctttga tccccttgct ttttgtagca attcgagagt tccagtttca ctagcttttc
     5941 cgaccatacg aatgttgaga aggccaacga ccgtaccgat aagcttgctc aaacggccgt
     6001 tcttcaccaa gttatcgact ttggctagga caaagagcaa cttagttttt tcttgatagg
     6061 cggtgatagc ttcaaccact tcttcaaaag acaagccctg gtcaatcaag tcattcaatt
     6121 tttctacgag taggtcaact tcaccaccag cagataaact atcaatcaca tgaatcttag
     6181 tgtcaggatg gtcttccaga taaatattct ttgctagttg agcactattg tgactgccag
     6241 aaagggtacc tgtgatggtt actaggaaaa tgtttttggc accttcaaat gctcgcaaat
     6301 agtcatctgg gcttggacaa gccgattttg aagcttctgc agttgcatac atggtttcca
     6361 tcatttggtc aatatcgaga ctggcgtcat caacaaagac ctgatcagct acttgaatgg
     6421 ttaaggggac gcttacaaag gttgtgttaa tagctggtgt tggcagttga cgataatcac
     6481 aaccagagtc agcaataatc ttccaagtca tagaaattct ccatctttgt cagttataca
     6541 ttgacaaagg ttctgtcttt ttttacaatt atatcatgaa aacccttgaa acaaaagcat
     6601 catccgtctg ttgtgacaag tagaaagaaa atgttatgtc tgaacgtaga atctctgaaa
     6661 agtctcttga aaatctcaga aaatcaaacc aagaatccaa tttattaacc agagaagcca
     6721 ttgaaacagc cctcttgcaa ctcttggaaa aaaaggaact gaccaagatt agtatttctg
     6781 aattggtcaa acgtgcaggt gtttcgcgtg cggcctttta tcgcaattat gactccaaag
     6841 aggaaatttt agagagcgtc tttaaacgaa ctgtccacaa tattatggaa cagctgcatc
     6901 attacgattt aaagacagac ctttatttgg tttgggttca ccttttccgg gaggccagaa
     6961 aggaagctag agtaattcaa ttggccttgg attaccatct ggaaaaaatc tttgtccaag
     7021 ccatgcagga atttctagaa aaataccatg ggaaatcaaa aggtgtcagc tcttatcttc
     7081 attccttctg gagctcagcc atcgtctctg tccttctaaa atggatcaag gatggcatga
     7141 aggtaccagc tgaaaagatt gcagatttag gtttaccatt ttttaaaaaa tagagaaaaa
     7201 ggagaaaaga gatgactgaa aaaagactgg cctgggatga gtattttgca gcccaagccc
     7261 tactaattgc gaatcgttcc acttgtaaac gtgctaaagt gggcgcgatt ctggtaaaag
     7321 ataataaggt tatttccact ggttacaatg gttcggtgtc agggactgag cattgtattg
     7381 atcacgaatg tttggtcatt gaaggccact gtgttcgcac ccttcacgct gaggtcaatg
     7441 ctatccttca aggtgctgag cgtggtgttc ccaaaggctt tacagcctat gtaacccatt
     7501 ttccttgtct caactgtaca aaacaattgc ttcaggtcgg ctgcaagcgt gtggtttata
     7561 tcaaccagta ccgaatggac gactacgccc aataccttta tcaagaaaaa gggacagaat
     7621 tgacccattt accacttgag acagtacaga cagctcttaa agaggctgat ctaatgtaaa
     7681 aattatcaaa aataaatggt ttagaaagat ttttaaaccg ttttttggta taataagaag
     7741 aataaattga aagaaggaat tccaaaaatg ggaaaaattg aagttattaa tcacccactg
     7801 attcaacaca aattgtcaat cttgcgtcgt acagatactt ctacaaaagc ttttcgtgag
     7861 ctagtagatg agattgcaat gttgatgggg tatgaagtac ttcgtgatct tccactagaa
     7921 gatgtggaaa tcgaaacacc aattacaaaa acagttcaaa aacaattggc aggtaagaaa
     7981 ttggccatcg tcccaatctt gcgtgcaggt atcgggatgg ttgatggtct cttgagcttg
     8041 gttccagctg ctaaagttgg ccacatcggt atgtaccgtg atgaagaaac acttcaacca
     8101 gttgaatact tggtgaaatt gcctgaggac attgaccaac gtcaaatttt tgtagtagac
     8161 ccaatgttgg caacaggtgg ctcagcaatc ttggctgttg attctcttaa aaaacgtggc
     8221 gcatcaaata tcaaatttgt ctgccttgta tctgctccag agggtgtaaa agcccttcaa
     8281 gaagctcatc cagatgtaga aatctttaca gcagccttgg atgaacgttt gaacgaacac
     8341 ggttatatcg ttccaggtct tggagatgct ggagaccgct tgttcggtac aaaataagat
     8401 cgaaaagaag aatgacttgg aaaagtattt ccagtcacga aaggaggttg ggtttttgtt
     8461 tctgtctaat gaaagcagag caaaaatttg accttttttg accaagatat tataatagtc
     8521 ttatcttcag tcatttgacc aacaaaatta aaactcaaaa ggagaaatga atgattcctg
     8581 tagttattga acaaacaagc cgtggagaac gttcttacga tatttactca cgtcttctca
     8641 aagaccgcat cattatgctg acaggtccgg ttgaagacaa tatggctaac tctgttattg
     8701 cccaactgct tttcttggat gcccaagata gtacaaaaga tatttacctt tatgtcaata
     8761 caccaggtgg ttctgtttca gctggtttgg caatcgtaga taccatgaac tttatcaagg
     8821 cagatgtcca aaccattgtt atgggaatgg ctgcatctat gggaacagtc atcgcatcaa
     8881 gtggagcaaa aggcaaacgt ttcatgcttc caaatgctga atacatgatt caccaaccaa
     8941 tgggcggtac aggtggtggt acccaacaaa ctgatatggc tatcgctgca gaacacttgc
     9001 tcaaaactcg taataccttg gaaaaaatct tggctgaaaa ttcaggtcag tcaatggaaa
     9061 aagtccatgc agatgcagaa cgtgataact ggatgagcgc ccaggaaaca cttgaatatg
     9121 gctttattga tgaaattatg gccaacaatt cattgaacta atgatgatag aaggcaaact
     9181 cgactgggtt tgcttttttt ggtataatag ggagagattt cttagaaaga ggatttatca
     9241 tgtttgaaaa agtcaatcgc tctggcttga ttatctatct ttactataat cgtgatgcca
     9301 aaaaactgca ggattatgga gatattacct atcattccaa gaaacatcgt tacttacaac
     9361 tctatgttcc aactcaagaa gtggagcaat tggtcggacg cttgagcaag gaaaaattta
     9421 ttaaaaaagt tagggtttgt catatccaag agttggaaac accctttgtg ggcaatcttt
     9481 atcgatagga aaacgttatc atcgaaaaag ttcaaggaaa acattgacaa ttttctgata
     9541 attcggtata ttcttaacag actatttaag aaataaggag acaaaaaaga tgaagaaaaa
     9601 atttgcccta tcgtttgtgg cgcttgcaag tgtagcactt cttgcagcct gtggagaagt
     9661 gaagtctgga gcagtcaaca ctgctggtaa ctcagtagag gaaaagacaa ttaaaatcgg
     9721 gtttaacttt gaagaatcag gttctttagc tgcatacgga acagctgaac aaaaaggtgc
     9781 ccaattggct gttgatgaaa tcaatggcgc aggtggtatc gatggaaaac aaatcgaagt
     9841 agtcgataaa gataataagt ctgaaacagc tgaggctgct tcagttacaa ctaaccttgt
     9901 aacccaatct aaagtatcag cagtcgtagg acctgcgaca tctggtgcga ctgcagctgc
     9961 ggtagcgaat gctacaaaag caggtgttcc attgatctca ccaagtgcga ctcaagatgg
    10021 attgactaaa ggtcaagatt acctctttat tggaactttc caagatagct tccaaggaaa
    10081 aattatctca aactatgttt ctgaaaaatt aaatgctaag aaagttgttc tttacactga
    10141 caatgccagt gactatgcta aagggattgc caaatctttc cgcgagtcat acaagggtga
    10201 aatcgttgca gatgaaactt tcgtagcagg tgacacagac ttccaagcag cccttacaaa
    10261 aatgaaaggg aaagactttg atgctatcgt tgttcctggt tactataatg aggctggtaa
    10321 gattgtaaac caagcgcgtg gtatgggaat tgacaaacca atcgttggtg gtgatggatt
    10381 caacggtgag gagtttgtac aacaagcaac tgctgaaaaa gcatcaaaca tctactttat
    10441 ctcaggcttc tcaactactg tagaagtttc agctaaagct aaagccttcc ttgacgctta
    10501 ccgtgctaag tacaatgaag agccttcaac atttgcagcc ttggcttatg attcagttca
    10561 ccttgtagca aacgcagcaa aaggtgctaa aaattcaggt gaaatcaaga ataaccttgc
    10621 taaaacaaaa gattttgaag gtgtaactgg tcaaacaagc ttcgatgcag accacaacac
    10681 agtcaaaact gcttacatga tgaccatgaa caatggtaaa gttgaagcag cagaagttgt
    10741 aaaaccataa tagaaaaatg ttgaaacagg gaatgagcct ttgactcact ccctgtttcg
    10801 atatttaata ctcttcgaaa atctcttcaa actgcgtcaa cgtcgccttg gattatatat
    10861 gtgactgact tcgtcagtct tatctacaac ctcaaagcag tgctttgagc aacctgcggc
    10921 tagtttccta gtttgctctt tgattttcat tgagtataag aacctatcaa aaagtgaggg
    10981 aaaaccctcg gaattataaa tagaaagagt gaatcttatg ctccaacaac tcgtaaatgg
    11041 tttgattcta ggtagtgttt acgcgctgtt agccctagga tataccatgg tttacggaat
    11101 tatcaagctc atcaacttcg cccatggtga tatttatatg atgggagcct ttatcggtta
    11161 tttcttgatc aattctttcc aaatgaattt ctttgtagcg cttattgtag ctatgctagc
    11221 gacagctatt cttggtgtcg tgattgagtt tcttgcttac cgacctttgc gccactctac
    11281 tcgtattgct gttttgatta cggctattgg ggtttctttc ctattggagt atggaatggt
    11341 ctatctggtt ggtgccaata cccgtgcctt ccctcaagcg attcaaacag ttcgatatga
    11401 tttgggacca attagcttaa caaatgtgca gttaatgatt ttgggcattt ccttgatttt
    11461 gatgattttg ttacaagtca ttgtccaaaa gactaagatg gggaaagcca tgcgtgcagt
    11521 atcagtagat agcgacgcgg cgcaattgat ggggatcaat gtaaaccgta cgattagctt
    11581 taccttcgct ttgggttctg ctcttgcggg tgcggctggt gttctgattg ctctttatta
    11641 taactctctt gagcctttga tgggggttac tccaggtctt aaatctttcg ttgccgcagt
    11701 acttggtggt atcggaatta ttcctggtgc ggctcttggt ggctttgtga ttggtctatt
    11761 ggaaaccttt gcgacagcct ttgggatgtc agatttccgt gatgccattg tttatggaat
    11821 cttgttgttg atcttgattg tccgcccagc tggtatcctt ggtaagaatg tgaaagagaa
    11881 ggtgtaaacg atgaaggaaa atttaaaagt taatattcta tggttactcc ttttgttagc
    11941 tggctatagc ttgattagtg tactggtttc agtcggagta cttaatctat tctatgtaca
    12001 gattttacaa caaattggaa ttaatattat tttggctgtt ggtctcaact taatcgttgg
    12061 tttttcagga caattttcac ttggtcatgc tggtttcatg gcgattggtg cctatgcagc
    12121 agctattatt ggttctaaat caccaaccta cggtgccttc tttggagcta tgcttgtagg
    12181 ggctttgctt tcaggagcag ttgccttact tgtcggcatt ccaaccttgc gcttgaaggg
    12241 ggactatctt gcggtagcaa ctctgggtgt ttctgaaatt atccgtatct ttatcatcaa
    12301 tggtggaagt cttacaaatg gtgcggcagg tatcttaggg attcctaact ttacaacttg
    12361 gcaaatggtt tacttctttg tcgtgattac aaccattgca accttgaact tcttgcgtag
    12421 cccaattggc cgttcaaccc tctctgttcg tgaagatgaa atcgctgctg agtcagttgg
    12481 ggttaatacg actaaaatta aaatcatcgc ttttgtcttt ggtgccatta ctgcaagtat
    12541 tgctgggtca cttcaggcag gatttatcgg gtctgttgta ccgaaagatt acaccttcat
    12601 caactcaatc aacgttttga ttattgttgt atttggtgga ctcggttcca ttacaggtgc
    12661 gattgtttcg gctattgttc tgggaatttt gaatatgctt ctccaagatg ttgctagtgt
    12721 gcgtatgatt atttacgctt tggccttggt attggtaatg attttcagac caggtggact
    12781 ccttggaacg tgggaactga gcctatcacg tttctttaaa aaatctaaga aggaggaaca
    12841 aaactaatgg cattacttga agtaaaacag ttaaccaaac attttggtgg tctaacagct
    12901 gttggagatg tgactcttga attgaacgaa ggggaactgg ttggattaat cggtccaaac
    12961 ggagctggga aaaccaccct tttcaacctt ttgaccggtg tttatgaacc aagtgaggga
    13021 acagtaaccc tagatggtca ccttttgaat gggaaatcac cttataagat tgcctctttg
    13081 ggacttggac gtactttcca aaatatccgt ctttttaaag atttaacagt tttagacaat
    13141 gttttgattg cttttggaaa ccatcacaaa cagcatgttt ttactagttt cttacgctta
    13201 ccagcttttt acaagagtga aaaagaatta aaggctaaag ctttggaatt gttgaaaatc
    13261 tttgatttag atggtgatgc agagactctt gctaaaaatc tttcctacgg acaacaacgt
    13321 cgtttggaaa ttgttcgtgc ccttgctacg gaacctaaaa ttctcttctt agatgaacca
    13381 gcagcaggta tgaacccaca ggaaacagcc gaattgactg agttaattcg tcgtatcaaa
    13441 gatgagttta agattacaat catgttgatt gaacacgata tgaatctggt catggaagta
    13501 acagaacgta tctacgtact tgaatatggc cgtttaatcg ctcaaggaac tccagacgaa
    13561 attaagacca ataaacgcgt tatcgaagct tatctaggag gtgaagccta atgtctatgt
    13621 taaaagttga aaatctttct gtgcattacg gtatgatcca agcagttcgt gatgtaagct
    13681 ttgaagttaa tgaaggagaa gttgtttccc ttatcggtgc caacggtgca ggtaagacaa
    13741 ctattcttcg caccttgtca ggtttggttc gaccaagttc aggaaagatt gaatttttag
    13801 gtcaagaaat ccaaaaaatg ccagctcaga aaatcgtggc aagtggtctt tcacaagttc
    13861 cagaaggacg ccacgtcttt cctggcttga ctgttatgga aaatcttgaa atgggagctt
    13921 tcttaaagaa aaatcgtgaa gaaaatcaag ctaacttgaa gaaggttttc tcacgctttc
    13981 ctcgtcttga agaacggaag aaccaagatg cagccactct ttcagggggg gaacaacaaa
    14041 tgcttgccat gggacgcgcc ctcatgtcaa caccaaaact tcttctttta gatgaaccat
    14101 caatgggact tgccccaatc tttatccaag aaatttttga tatcattcaa gatattcaga
    14161 agcaaggaac aacggtcctc ttgattgaac aaaatgccaa taaagcactt gcaatctctg
    14221 accgaggata tgtactggaa acagggaaaa tcgtcctatc aggaacagga aaagaactcg
    14281 cttcatcaga agaagtcaga aaagcatatc taggtggcta aaacaatcca gtggattgtt
    14341 ttagtcggca gatggagatt acgaagtaat catcaatata gtccggggga cctttttagt
    14401 cggtagattg agattgcaaa caaatctgca tctacattga aagcttaatt tctaataatt
    14461 gaaaaaatcg aatgaaaaat ttcttacctt cattcacaga gctcgatttc agagctcttt
    14521 ttgctagctt attcatactt ttttgaattt cgaaaaagaa atgtaagcgt ttgatagatt
    14581 tacaaaaaga ttgtataatg gggataagaa tagaaaagga gaagtctcat ggcagttaaa
    14641 gattttatga cccgcaaggt agtttatatt agtccagata caacagtatc tcatgcagca
    14701 gatttgatga gagagcaagg attgcaccgc ttgcctgtta tcgaaaatga tcaattggtt
    14761 ggtttggtga ctgagggaac cattgcacaa gcaagtccat ctaaagcaac aagtctttct
    14821 atctatgaga tgaattatct tctgaataag acaaaagtaa aagatgtcat gattcgcgat
    14881 gttgtcactg tctcaggcta tgctagtcta gaagatgcaa cttatctgat gttgaaaaat
    14941 aagattggta ttctccctgt cgtagataac catcaagtat acggagttat tactgaccgt
    15001 gacgttttcc aagcctttct tgaaattgca ggttatggcg aagaagggat tcgtgtacgc
    15061 tttgttacag aagatgaagt tggtgttctt ggaaaaatta tttctttgat tgtagaagaa
    15121 aatttgaata tatcccatac agtcaatatt ccgcgtaagg atggtaaggt cattatcgaa
    15181 gtgcaaatcg atggatcaat tgatttacca gccttgaaag aaaaatttga agcaaatggt
    15241 attcaagtgg aagaaatcgc tcgcacttca gcaaaagtct tgtaagaagg gaagccaaag
    15301 gcttcttttt tcatgaaaag gggattagag caaaagatgg aaagaaatga taaaatatgc
    15361 tataatgaaa taatgtaaaa aaggagtatt tatggacatt tcagtaattc gtcagaaaat
    15421 tgacgcaaat cgtgaaaaat tagcttcttt cagggggtct ctttgacctc gaagggctag
    15481 aggaagagat tgccatcttg gaaaacaaga tgacagaacc tgatttttgg aacgataata
    15541 ttgcggccca aaaaacgtcg caagaattga atgaattaaa aaacacttac aataccttcc
    15601 ataagatgga agagttgcag gatgaagtcg aaattttatt ggattttttg gctgaagacg
    15661 agtcagtgca tgatgaactg gtagcgcagt tagccgaact tgataagata atgactagtt
    15721 acgagatgac tctactcttg tcagaacctt atgaccacaa caatgccatc ttggaaatcc
    15781 atccaggttc tggtggtact gaggcgcagg actggggtga tatgttgctt cgtatgtata
    15841 ctcgttatgg taatgctaaa ggctttaaag tggaagtgtt ggattaccaa gcaggtgatg
    15901 aggctggtat taagtcggta actttatcat ttgaagggcc taatgcctat ggtctcctca
    15961 agtcagaaat gggtgttcat cgcttagtgc gaatctcacc atttgactct gccaaacgtc
    16021 gccatacctc tttcacatct gtagaagtga tgccagaatt ggatgatact attgaagtgg
    16081 aaatccgtga agatgatatc aagatggata ccttccgttc aggtggtgcc ggtggacaaa
    16141 acgtcaataa agtttcaaca ggtgtacgtt taacccacat tccaactgga attgttgtcc
    16201 aatcaacagt ggatcgtacc cagtatggaa atagagatcg tgccatgaag atgttgcagg
    16261 ctaagctcta tcaaatggag caagataaga aggctgcgga ggtagattct ctcaaaggtg
    16321 agaaaaagga gatcacttgg ggaagccaaa tccgttctta tgtcttcacg ccttatacta
    16381 tggtaaaaga tcaccgaact agctttgagg ttgctcaggt agataaggtt atggatgggg
    16441 acctagatgg ttttatcgat gcttatctca agtggcgaat tagctaagat agaaaggaac
    16501 tcacatgtca attattgaaa tgagagatgt cgttaaaaaa tacgacaacg gaacgactgc
    16561 tctacgcggt gtttcggtta gcgttcaacc gggggaattt gcctacatcg taggaccttc
    16621 aggagcaggg aagtcaactt ttattcgttc tctgtatcgt gaagtaaaaa tcgataaagg
    16681 aagcctatca gttgctggtt ttaatctggt taagatcaaa aagaaagatg tcccgcttct
    16741 acgtcgtagt gttggggttg tcttccagga ttataaactg ttaccaaaga aaactgtcta
    16801 tgaaaatatt gcttacgcta tggaagtaat cggggaaaat cgccgtaata tcaaaagacg
    16861 agtgatggaa gttttggact tggttggatt gaagcataag gttcgttctt ttccaaatga
    16921 actctcaggt ggggagcagc agcggattgc gattgcgcgt gcaattgtaa ataatcccaa
    16981 agtattgata gctgatgagc caacaggaaa tctggatccg gataattcat gggaaattat
    17041 gaatctcttg gaacggatta acctacaagg aacaactatt ttgatggcga ctcataatag
    17101 ccagattgta aataccttgc gccaccgtgt cattgccatt gaaaatggcc gtgtcgttcg
    17161 tgacgaatca aaaggagagt atggatacga tgattagtag attttttcgc catttatttg
    17221 aagccttaaa aagtttgaaa cgaaatggtt ggatgacagt agctgctgtc agttcagtca
    17281 tgattacttt gaccttggtg gcaatatttg catctgttat tttcaataca gcgaaactag
    17341 ctacagatat tgaaaataat gtccgtgtag tagtttatat ccgaaaggat gtggaagata
    17401 atagtcagac aattgaaaaa gaaggtcaaa ctgttacaaa taatgactac cacaaggtat
    17461 atgattcttt gaagaacatg tctgcggtta aaagtgttac cttttcaagt aaagaagaac
    17521 aatatgaaaa attaaccgag ataatgggag ataactggaa aatctttgaa ggagatgcca
    17581 atcctctcta tgatgcttat attgtagagg caaacactcc aaatgatgta aaaactatag
    17641 ccgaagatgc taaaaaaatt gaaggtgtct ctgaggttca agatggcggt gccaatacag
    17701 aaagactctt caagttagct tcatttatcc gtgtttgggg actagggatt gctgctttgt
    17761 taatttttat cgcagttttc ttgatttcaa ataccattcg tattaccatt atttcccgca
    17821 gtcgcgaaat tcaaatcatg cgcttggtcg gagctaaaaa cagttatatc cgtggaccgt
    17881 tcttgttaga aggagccttt atcggtttat tgggagctat cgcaccatct gttttggtct
    17941 ttattgttta tcaaattgtt taccaatctg tcaacaaatc gttggtaggg caaaatctat
    18001 ccatgattag tccagattta tttagtccgt tgatgattgc cctactattt gtgattgggg
    18061 ttttcattgg ttcattggga tcaggaatat ccatgcgccg attcttgaag atttaggtaa
    18121 aatagctgct tttatgagga gattgtaaaa tctccttttt tgctacaaga gtttttgaaa
    18181 agagattcca aagaagtccc ccagagaaga cttcttgatg gctaatttga acttgaaatt
    18241 tggcgcacta gaaatttttt agaaaaaagt gtaatttttt tataaaagcc tttacaaaaa
    18301 aaattaaagt ggtataatta aatcatagaa agtgcaaacg ttttcgtaaa acgtttgcct
    18361 aaataaaaat aaaggagatt tgaatgatga aagatacatt caaaaatgtc ttgtctttcg
    18421 aattttggca aaaattcggt aaggctttga tggtagttat cgcggttatg ccggctgctg
    18481 gtttgatgat ttcaatcggt aagtctatcg tgatgattaa cccaaccttt gcaccacttg
    18541 tcatcacagg tggaattctt gagcaaatcg gttggggggt tatcggtaac cttcatattt
    18601 tgtttgccct agccattgga ggaagctggg ctaaagaacg tgctggtggt gctttcgccg
    18661 ctggtcttgc cttcatcttg attaaccgta tcactggtac aatctttggt gtatcaggcg
    18721 atatgttgaa aaatccagat gctatggtaa ctactttctt tggtggttca atcaaagttg
    18781 ctgattactt tatcagtgtt cttgaagctc cagccttgaa catgggggta ttcgtaggga
    18841 ttatctcagg ttttgtaggg gcaactgctt acaacaaata ctacaacttc cgtaaacttc
    18901 ctgatgcact ttcattcttc aacgggaaac gtttcgtacc atttgtagtt attcttcgtt
    18961 cagcaatcgc tgcaattcta cttgctgctt tctggccagt agttcaaaca ggtatcaata
    19021 atttcggtat ctggattgcc aactcacaag aaactgctcc aattcttgca ccattcttgt
    19081 atggtacttt ggaacgtttg ctcttgccat ttggtcttca ccacatgttg actatcccaa
    19141 tgaactacac agctcttggt ggtacttatg acattttaac tggtgcagct aaaggtactc
    19201 aagtattcgg tcaagaccca ctatggcttg catgggtaac agaccttgta aaccttaaag
    19261 gtactgatgc tagtcaatac caacacttgt tagatacagt acatccagct cgtttcaaag
    19321 ttggacaaat gatcggttca ttcggtatct tgatgggtgt gattgttgct atctaccgta
    19381 atgttgatgc tgacaagaaa cataaataca aaggtatgat gattgcaaca gctcttgcaa
    19441 cattcttgac aggggttact gaaccaatcg aatacatgtt catgttcatc gcaacaccta
    19501 tgtatcttgt ttactcactt gttcaaggtg ctgccttcgc tatggctgac gtcgtaaacc
    19561 tacgtatgca ctcattcggt tcaatcgagt tcttgactcg tacacctatt gcaatcagtg
    19621 ctggtattgg tatggatatc gttaacttcg tttgggtaac tgttctcttt gctgtaatca
    19681 tgtactttat cgcaaacttc atgattcaaa aattcaacta cgcaactcca gggcgtaacg
    19741 gaaactacga aactgctgaa ggttcagaag aaaccagcag cgaagtgaaa gttgcagcag
    19801 gctctcaagc tgtaaacatt atcaaccttc ttggtggacg tgtaaacatc gttgatgttg
    19861 atgcatgtat gactcgtctt cgtgtaactg ttaaagatgc agataaagta ggaaatgcag
    19921 agcaatggaa agcagaagga gctatgggtc ttgtgatgaa aggacaaggg gttcaagcta
    19981 tctacggtcc aaaagctgac attttgaaat ctgatatcca agatatcctt gattcaggtg
    20041 aaatcattcc tgaaactctt ccaagccaaa tgactgaagc acaacaaaac actgttcact
    20101 tcaaagatct tactgaggaa gtttactcag tagcagacgg tcaagttgtt gctttggaac
    20161 aagtaaagga tccagtattt gctcaaaaaa tgatgggtga tggatttgca gtagaacctg
    20221 caaatggaaa cattgtatct ccagtttcag gtactgtatc aagcatcttc ccaacaaaac
    20281 atgcttttgg tattgtgacg gaagcaggtc ttgaagtatt ggttcacatt ggtttggaca
    20341 cagtaagtct tgaaggtaaa ccatttacag ttcatgttgc tgaaggacaa aaagttgcag
    20401 caggagatct ccttgtcaca gctgacttgg atgctatccg tgcagcagga cgtgaaactt
    20461 caacagtagt tgtcttcaca aatggtgatg caattaaatc agttaaatta gaaaaaacag
    20521 gttctcttgc agctaaaaca gcagttgcta aagtagaatt gtaatatact tgaggttgga
    20581 agctgtattc caacctctta ttttgggaga aaagaatgaa atttttaaca ctcaatactc
    20641 acagttggat ggagaaagaa gcagaggaaa aattccagat tttgcttgaa gatattcttg
    20701 aaaaggacta tgatttgatt tgttttcaag aaatcaatca ggagatgacc tcgtcagagg
    20761 tggaggttaa tgacctttat caagctttgc cagcagctga gcctattcac caagaccatt
    20821 atgttagact cttggttgaa aagttgttag agcaagggaa aaattactac tggacctggg
    20881 cttataacca tatcggctat gaccgctacc acgaaggtgt ggctatcttg tctaaaacac
    20941 ctattgaagc cagagaaatt ttggtttcag atgtggatga tccaacagac tatcatactc
    21001 gccgtgttgc cctagctgaa actgtagttg atggcaagga gctagcagtt gccagtgttc
    21061 atctctcttg gtgggataaa ggtttccaag aagaatgggc acgatttgag gctgttttga
    21121 aaaaattgaa caagccactt ttactagctg gagattttaa caacccagca ggtcaggaag
    21181 gttaccaagc tattttagct agtccattag gcttacaaga cgcatttgaa gttgctcaag
    21241 agaaaagtgg tagctatact gttccgcctg aaattgatgg ctggaaaggg aacactgaac
    21301 cccttcgaat cgattatgtc tttactacca aagagttagc ggtggaaaat ttacatgtcg
    21361 tatttgatgg taacaagagt ccacaagtga gtgatcacta tggcttgaat gctatgttaa
    21421 actggaaata ataactgaaa agaggttgga actataaaat tccagccttt tcttactaga
    21481 gaagctactg gaaatagcct aaataagtga gactactgta atggaataaa atatggtata
    21541 attgataaga tagatagaat cgaggatgtt atgtcattta cgaaatttca atttaaaaac
    21601 tatattagag aagccttgaa ggagttaaaa tttacaactc caacagaggt gcaagacaag
    21661 ttgattccta ttgttttggc aggtcgtgac ctagtaggag aatcaaaaac aggttcaggt
    21721 aagactcata ctttcttgtt accgattttc cagcaattag atgaagctag cgatagtgtg
    21781 caagcagtga ttactgcacc gagtcgtgag ttggctactc aaatttacca agtagcgcgt
    21841 cagatttcag ctcactcaga tgtcgaagtt cgtgtggtta attatgtggg tggtacggat
    21901 aaggctcgcc agattgagaa attggcaagc aatcagcctc atattgttat tggaacacca
    21961 ggccgtatct acgacttggt taaatctggt gatttagcta ttcataaagc caagacattt
    22021 gttgttgatg aagcagatat gaccttggat atgggattct tggaaactgt tgataagatt
    22081 gctggcagtc ttccaaaaga cttgcaattc atggtcttct cagcgactat cccacaaaaa
    22141 ctgcaaccat tcttgaaaaa atacttatca aatcctgtta tggagaaaat taagaccaaa
    22201 acggttattt ctgacaccat tgataattgg ttgatttcga ccaagggaca tgataagaat
    22261 gctcaaattt accagttgac tcagttgatg cagccgtatt tggcaatgat ttttgttaac
    22321 actaaaacgc gtgctgatga attgcattca tatctgactg ctcaaggctt gaaggttgca
    22381 aaaatccatg gagatattgc ccctcgtgaa cgcaagcgaa tcatgaatca ggtgcaaaat
    22441 ctggattttg agtatattgt cgcaacagat ttggcagcgc gtgggattga cattgaaggt
    22501 gtcagccatg tcatcaatga tgccattccg caagacttat ctttttttgt tcatcgtgtt
    22561 ggtcgtactg gacgaaatgg cctaccaggt acagctatta ccctttatca gccaagtgat
    22621 gactcggata tccgtgagtt ggagaaattg gaaatcaagt ttagtcctaa gatggtcaaa
    22681 gacggggaat ttcaagatac ctatgaccgt gatcgtcgtg ccaaccgtga gaaaaaacaa
    22741 gataaacttg atatcgaaat gattggtttg gttaaaaaga aaaagaaaaa agtcaaaccg
    22801 ggttataaga agaaaattca atgggcggtt gatgaaaagc gccgtaaaac caagcgtgct
    22861 gaaaatcgcg ctcgcggtcg tgcagagcgt aaagctaaac gccaaacatt ttaatagaaa
    22921 ttgttggagt attgagctcc aactttttgc tttatgagaa cgaactatct aaaccgaaac
    22981 actacattaa agactgcaaa ttgcgattaa aaatggtata atgataaagt tatatagtcc
    23041 cgataagatg gtaggtattt attacgaaga gttttcctat cagtactttg taactctata
    23101 acaatatttt ttaagggggg acatttttat gtcagaacgt aaattattca cgtctgaatc
    23161 tgtatctgag gggcatccgg ataagattgc agaccaaatt tcagatgcga ttttggatgc
    23221 tattttagca aaggatccag aggcgcacgt tgctgctgaa acagctgtat atactggttc
    23281 tgtccacgtt tttggtgaaa tttctacaaa tgcctatgtg gatattaacc gtgtggttcg
    23341 tgataccatt gcagagattg gttataccaa tacagaatat ggattttctg ctgagacggt
    23401 gggagtacac ccatctttgg tggaacaatc tcctgacatc gctcaaggtg ttaacgaagc
    23461 cttggaggtt cgtggaaatg ctgatcaaga tccactggac ttgattggag caggtgacca
    23521 agggctcatg tttggatttg cagtagatga aacagaagag ctcatgccat tgccaattgc
    23581 actcagtcat aaattggttc gtcgtctggc agaacttcgt aagtctggag aaattagcta
    23641 tctccgtcca gatgcaaaat cacaagttac agttgagtac gatgaaaatg accgtccggt
    23701 acgtgtagat acagtcgtta tttctactca gcatgatcca gaggccacta atgaacaaat
    23761 ccatcaagat gtgattgaca aggtcatcaa agaagttatt ccatcttctt atcttgatga
    23821 taagacaaaa ttctttatca atccgacagg tcgttttgta atcggtggtc ctcaagggga
    23881 ctcaggtttg actggtcgta agattattgt agatacttat ggtggctact ctcgtcatgg
    23941 tggtggtgcc ttctctggta aagatgcgac taaggtggat cgttcagcct cttatgcggc
    24001 tcgctatatt gccaagaata tcgttgcagc agaccttgct aagaaggcag aagtgcagtt
    24061 ggcctatgct atcggtgttg cgcaacctgt ttctgttcgt atcgatactt tcggtacagg
    24121 aacagtagct gaaagtcaac ttgaaaaagc ggctcgtcaa atctttgacc ttcgccctgc
    24181 agggattatc caaatgctgg accttaagcg tccaatttac cgtcaaacat cggcttacgg
    24241 tcacatggga cgtacagata ttgatcttcc atgggaacgt ttggataagg tagatgcttt
    24301 gaaagaagca gtaaaataag attttaagag gggaacgtcc tctctttttt atagttttta
    24361 actatactgg gatactgttc tgaaaatcca ttttgcgaaa gtagagattt acatgtatag
    24421 tagattgaaa ctaaaatagt acacttgaac ttctaaaaca ttgttagaaa tcgatttgac
    24481 tgtcctgatc gatttctcct gttcttgttt cattttacta tatttcttta aaaatgataa
    24541 aggttgagat ttctccttgt tgcttggact tcattcaaaa gtctgttacc caagccttgt
    24601 tcaaacttcc aatacactag ctgtttccat agcatgactt ctgtactaga ctttcttttc
    24661 cgaataaata gatagaacca cagaatctag taaacctaga attaaaatta tggtataata
    24721 ttagcaataa aagaaatctg gaggattaga atcatggtat caacgaaaac acaaattgct
    24781 ggttttgagt ttgacaattg cttgatgaat gcagcaggtg tggcttgtat gacgataaag
    24841 gagttagaag aggtcaaaaa ctcagcggca ggaacctttg ttactaagac agcgaccttg
    24901 gatttccgtc aggggaatcc tgagccacgc taccaagatg ttccacttgg ttccatcaac
    24961 tctatgggct tgccaaataa tggcttagac tattatttgg attatctttt agatttgcag
    25021 gaaaaagagt cgaaccgaac tttcttctta tctctggtcg gcatgtctcc agaggaaacc
    25081 catactattt tgaaaaaagt ccaagagagt gattttcgtg gtctgactga gctaaatctt
    25141 tcctgtccaa atgttccagg taaacctcag attgcctatg attttgagac aacagaccgg
    25201 attttggcag aagtgtttgc ttacttcacc aaacctcttg gaattaaatt gccaccttat
    25261 tttgatattg ttcactttga ccaagcggca gctattttca acaaatatcc gctcaagttt
    25321 gtcaactgcg ttaactctat cggaaacggc ctctatatag aagacgagtc tgtcgttatt
    25381 cggcctaaga atggttttgg tggaattggt ggagaataca tcaaaccgac tgctctagcc
    25441 aatgttcacg ccttttatca acgtttaaat cctcaaatcc aaattatcgg aacaggtggc
    25501 gttctgactg gtcgagatgc ctttgaacac atcctctgtg gagcaagtat ggtgcaggtg
    25561 ggaacgaccc ttcacaaaga aggcgtcagt gcttttgacc gcattaccaa tgaactgaaa
    25621 gcaatcatgg tggaaaaagg ctacgagagc ttagaagatt tccgtgggaa attgcgctat
    25681 attgactaaa ttaaatcgaa aaatctgaag aaaggagaga cgatgctagc cattgaagaa
    25741 agtcagaagt tgactttatc aaatttaccg agcctgagcc tatttacagg gacagatcag
    25801 ggtcagtttg aagtgatgaa gagtcaaatg ttgaaacaga ttgggtatga ttctgctgac
    25861 ctcaactttg cctactttga tatgaaagaa gtagtttaca aggatgtgga actggagttg
    25921 gtcagccttc ctttctttgc ggatgagaaa atcgtgatat tagattattt tatggatatc
    25981 acgactgcta agaaacgctt tttgacagat gatgagctta agtcatttga ggaatacctt
    26041 gacaatcctt ctccaacaac caagttgata atctttgcag aaggaaagct ggatagcaaa
    26101 agacggttag tcaaattact taagcgtgat gccaaggcct tcgatgcagt agaagtaaaa
    26161 gaacaagaat tgcgccagta cttccaaaag tggagtcaga aacaaggtct gcagtttacc
    26221 aatcattctt ttgaaaatct cctcatcaag tcggggtttc aatttagcga aatccagaaa
    26281 aatcttctct ttttacagtc ctataaggtg gattctgtta tcgaggaaga ggatattgtt
    26341 aacgcaattc ccaagacctt gcaggacaat atttttgatt taactcagtt tattctgact
    26401 aaaaagatgg atcaggcgcg cgatttggtg agagacttga ccttgcaagg ggaagatgaa
    26461 atcaaactga ttgcagtcat gctgggacaa tttcggactt ttactcaggt gaagattttg
    26521 gcggagtctg gccaaacaga atcgcagatt gcaagtagtt taggtagtta tctgggacgt
    26581 aacccaaatc cttaccaaat caagtttgca ttaagagatt cgagaggact ttctttgagc
    26641 tttctgaagc aagctatttc ctatttgatt gagacagact atcagattaa gacaggtctt
    26701 tatgaaaaag gtttcctttt tgaaaaggca ctcttacaga ttgctagtca ggtcaattga
    26761 catttgttga aactacaacc cgcgccagga ttatcttgtc gtgggtttct tgctgatttg
    26821 cttattttat tagaaagtat gtcagtgatt tgcttatcta taagcaaaaa acttgaaaaa
    26881 agtgaatgtt tgcgttatca ttttcatata gaaagaaaaa gaggtattac agatggctat
    26941 tatcttacca gaacttccat atgcatacga cgctttggaa ccatacatcg atgcggaaac
    27001 aatgcatttg caccatgaca aacaccatca aacttatgtc aacaatgcca atgcagcttt
    27061 agaaaaacac cctgaaatcg gtgaagacct tgaagccttg cttgctgatg tagaatctat
    27121 cccagctgat atccgtcaag cacttatcaa caatggtggc ggacacttga accacgctct
    27181 tttctgggaa ttgatgactc ccgagaaaac agctccttca gcagagctgg cagcagcaat
    27241 cgatgcaaca tttggttcat ttgaagaatt ccaagcagcc ttcactgcag cagcaacaac
    27301 tcgttttggt tcaggttggg catggttggt tgtcaacaaa gaagggaaac ttgaagtgac
    27361 ttcaacagca aaccaagaca caccaatctc agaaggtaaa aaaccaatct tgggcttgga
    27421 cgtttgggaa catgcttact acgtgaaata ccgcaacgtg cgtcctgact acatcaaagc
    27481 tttcttttca gtaatcaact ggaataaagt agatgaattg tacgcagctg ctaaataatg
    27541 atagttggag ggaagaattg ttcttctctt ttttaggtta taagattctg gtctgacaaa
    27601 atcgtcagac ttttttcatt tttatgagaa acgtgctaac tgctagaaat tatggtagaa
    27661 taaagtatta agtaatcgtg gaaaaaggat atctatgcga aaagaaattg cacctgaatt
    27721 atacaactat aacaagtttc ctggtccgga gttccattta cacggggaca aggtcgaaac
    27781 ggaagggata gctttttcct tggttgaaaa tatcaaggat gcctttgatg tgacgacttt
    27841 taatcagcgt ttttcagaag tattaaccaa gtttgattat atcgtggggg actggagcaa
    27901 cgaacagctt cgcctacgag gtttttacaa ggatgaccga acagaagaaa aacttgaaaa
    27961 aatcagttgt ttacaagact accttttaga gtattgtagt tatggttgtg cctattttgt
    28021 cttagaaaat gaagccccta agcgagcatc atttgacaag aaaatgcgta agacggaaga
    28081 agaaacacct tctagaaaag gaaagaaacc gactcaaact aaacgaaagt cgaatgcaga
    28141 taagaaaaat agacgtcgtc agaaagacca gcattctcat aaagaggaca agggacaacg
    28201 tcattttgtc attcgtcaga agtgagtaga gaataaggag aagaaatgaa accctcaatt
    28261 catagtttgg cacatcaaac catgcaggaa tgggtattgg agcagggaga aaagaaattc
    28321 cgtgcagatc aaatctggga atggctctac cgtaaacgtg tgcagtcatt tgaagaaatg
    28381 accaaccttt ccaaggattt gattgctaag ctcaatgacc agtttgtggt caatcccttg
    28441 aaacaacgta ttgtgcaaga gtctgctgat ggtacagtca aatatctctt tgaattgcct
    28501 gacggtatgt taattgaaac tgtactcatg cgtcaacact atggtttatc tgtctgtgtg
    28561 accactcagg tcgactgtaa tatcggttgt accttctgtg cctctgattt gattaagaag
    28621 caacgtgacc tcaataacgg tgaaatcgta gcgcaaatca tgctggttca gaaatacttt
    28681 gctgagcgtg gtcaggatga acgcgtcagc catatcgttg tcatgggaat cggtgagccc
    28741 tttgataatt acaacaatgt cttgaatttc gtttgtacta tcaatgatga taaaggaatg
    28801 gctatcggtg ctcgtcacat cacggtttca acctcaggtt tggctcataa aattcgtaac
    28861 tttgctgatg aaggggttca ggtcaatctt gccgtgtctc ttcacgcacc caacaatgaa
    28921 cttcgttcaa gtatcatgaa gattaaccgt gcctttccga ttgaaaaact ctttgctgct
    28981 attgaatact acattgagac aacaaaccgt cgtgtaacct ttgaatatat catgcttaat
    29041 gaagtcaacg acggtgtaga acaagccttg gaattggctg aattgctcaa gaacatcaag
    29101 aaattgtctt atgtaaactt gattccttat aacccagtta gtgagcatga ccaatatagc
    29161 cgtagtccca aagagcgcgt gttggctttc tatgatacgc ttaagaaaaa aggggtcaac
    29221 tgtgtggttc gtcaagagta tggtacagat attgacgcag cttgtggaca attgcgctct
    29281 aacacaatga aacgtgaccg ccagaaggca gtcgcagagg taaatccgta aaatgactaa
    29341 aaaaagagaa ttaatcttaa gattgggagt ggctgtttat agcctatgca ttgtctattt
    29401 ttgctttact cctcaagcta ccgtggaagt gggaactcca ggtattcagc atcttggacg
    29461 cctggttttt cttttgactc ctttcaattc tctctggaaa ctgggcgaag tgagtgacat
    29521 tggacaatta tgttggattt ttttacaaaa tatcctcaat gtcttcttgt tttttcctct
    29581 gattttccaa ctcctttatc tatttccaaa tttgcggaaa acaaaaaagg tccttctttt
    29641 tagttttctt gtgagtcttg gaatcgagtg tacgcaatta atcttggact ttttctttga
    29701 tttcaatcgc gtctttgaga ttgatgattt gtggaccaac actttgggtg gctatctggc
    29761 ttggctcctt tataaacgat tacataaaaa caagataagg aattaaaatg agtattttag
    29821 aagttaaaaa tctgagtcac ggttttggtg accgtgcaat ttttgaagat gtgtccttcc
    29881 gtctcctcaa gggagaacat atcggcttgg tcggtgccaa tggtgaagga aaatcaacct
    29941 ttatgagtat cgtgactggt aaaatgctgc cagatgaagg aaaggttgag tggtccaaat
    30001 atgtgacggc tggttacttg gatcagcact ctgtccttgc tgaaagacag tcggtgcgtg
    30061 atgttctccg tacggctttt gatgagcttt tcaaagctga agctcgtatc aatgacctct
    30121 atatgaaaat gactgaagac ggtgcggatg ttgatgctct catggaagaa gtaggagaac
    30181 ttcaagaccg tctggagagt cgtgatttct atatcttgga tgctaagatt gacgaagtag
    30241 cgcgtgctct tggtattatg gactttggca tggatacgga tgtaacttct ttgtcaggtg
    30301 ggcaaagaac caaggtgctt ttggcaaaac ttctccttga aaagcctgat attttgctgt
    30361 tggacgagcc gaccaactac ttggatgctg agcatattga ttggctcaag cgctatctcc
    30421 aaaactatga gaatgccttt gttctcattt cgcacgatat tccattcctc aatgacgtta
    30481 tcaatattgt ctatcatgtg gaaaatcaac agctgacgcg ttactctggt gactactacc
    30541 agttccaaga agtttatgct atgaaaaaat ctcagctaga ggcagcctac gaacgccagc
    30601 agaaagagat tgcagacctc aaggactttg tggctcgtaa taaagcccgt gttgcaactc
    30661 gtaatatggc tatgtctcgt caaaagaaat tggataagat ggatattatc gaactccaaa
    30721 gtgagaaacc aaaaccatcc tttgatttca aaccagctcg tacaccaggg cgctttatct
    30781 tccaagccaa gaacttgcaa attggttacg accgtcctct tactaagtct ttaaatctta
    30841 ccttcgaacg caatcaaaag gttgcgatta ttggtgctaa tggtattgga aaaacaactc
    30901 tcttgaagag tctcttgggc attatctcgc caatcgctgg ggaagtggag cgtggagatt
    30961 atttagaact tggttatttt gagcaggaag tagaaggtgg taatcgccaa actcctcttg
    31021 aagctgtctg gaatgccttt cctgccctta atcaagcaga agtccgtgca gcccttgccc
    31081 gttgtggttt gacaaccaaa catattgaaa gccagattca agtattatca gggggagagc
    31141 aagccaaggt tcgtttctgt ctcttgatga atcgtgaaaa caacgtttta gtgctggacg
    31201 agccgaccaa ccatttggat gtggatgcaa aggatgagct caaacgcgct ctcaaagaat
    31261 acaggggatc tatccttatg gtctgccacg agccagactt ttatgaaggt tggatagacc
    31321 aaatatggga ttttaataat ttaacttaag aatgagagta aaagaaatac agtaccgaat
    31381 gtggatactg tatttttttg gtttttaaga tttaaaatcg tagtctttca ccacttcgat
    31441 gctgtcgatt gtgatagcag tagttggctt gtctttttca tctttttcgg ctttagcaat
    31501 cttatccaca acatccatac cgtcaatcac ttgaccaaag actgggtgtt tgccgtctag
    31561 actagggttt ccaccttctt tgtaggcttc gataattttc tgtggatact tgcttgtagg
    31621 gagtttagaa gaggtatctg tagagttttg gttgatgaag aactggctgc cattggtgtt
    31681 tggttgacca gtattagcca tagcaagagc accacggatg ttatacaaat aaggagtaat
    31741 ctcgttcttg aaaccagttc ctttgtcttt agtcttatcc ttgtcatgcc agatggactg
    31801 accacctgta ccgtcccctt ttggatctcc agtttggacc ataaagccat cgatgacacg
    31861 gtggaaggta ataccgttat agtagccttc tttggcgtga gtgaggaaat tttcaaccgc
    31921 tagaggagcg agtttaggga agagtttaat gcgaatatca ccttggcttg tgtggagaat
    31981 cacttcggct tcatcttcag caacttcctt agatagttgt gggaaattgg cgttttcgtt
    32041 tgttaaagca tggtttaact ccttggcaga ttgggcagct actttggaac tttcttcagc
    32101 agcaagactg gaatcaacat aatcatcacc acgcagactg cgttggacgc tgctacaccc
    32161 agctagggct acagtagaca gtaaaagaag ggttgctagt tttttcattc tgttcctctc
    32221 aaaaattcat ttataccatt gtaccctaaa aggaagtgga tttcaaatat tagtagttta
    32281 cagaactggc ttagataata gttgggattt catcatcatc ttgaaaatct tcaacttctt
    32341 ccccagtaaa tggtttctga aaagaactta gtataaaacg ggcaattggt tcaacaatta
    32401 ggaaatttag aggaagagct gcaataaagt ttacgaacca ggcgcttaga taggtattgg
    32461 gtgtgatagc aatgccattg taaaaaagtc catagaagga catgaaagtg accagctaat
    32521 tcttcttctg aaaaatgctc atgaagggct tgatccaggt cgcaagattt cattttagaa
    32581 agtccagtaa ttcccttctt cttcaggata ttctttttca tggtagtatt tagatggtca
    32641 agtgagtcaa aagaagtttc gacaagagca tacccttttt ctaccagagt ttttagatgt
    32701 ttagggggca tcaataccat aagtgtactc aaagtatttt ggaaaccaga tcttaagaaa
    32761 gctcgtaaag ctagtcagtt ctctaaacgc taagaactag ctacaacaca gcatttacaa
    32821 cacttcatgg ttcacaccat ggggtgtttt ttaatgattt taagcaaaat tcacacttaa
    32881 ttgaaagtta tttaaattag atgaaaattt attttttgaa aaagtgggaa aacattgatt
    32941 ctaagcgaat tttgaatcat attcgaatgg gagtttttaa aatcatgttt cagtggtaaa
    33001 agtaccaaac tggattctcc atagtaaaat gatatctcct gctagtgaat catctgctaa
    33061 taagtccata tttcgcttgg gaacgggctt gggacttagg agccaagtat ccaaatctcg
    33121 ttcaggcgat atgaagggtt tgacttggtg ttctttataa aatttttcta aaatagtatt
    33181 cacggatagc atctttcaaa catttatttc ctattctaac aaatttctaa atactttaag
    33241 aaatttatag tctgtcaagt ttttttcttg acacatgcca gaaatctgct ataatagaac
    33301 atgtgctaaa tagctcagct atttcaccga aataaaaaat taaagaaatg agactttaaa
    33361 aatggcagtt aaaatccgtt tgactcgtat gggttctaag aaaaaacctt tctaccgtat
    33421 caacgtagca gattcacgtt caccacgtga cggacgtttc atcgaaacag ttggaactta
    33481 caacccactt gttgctgaaa accaagtaac tttgaaagaa gaccgcgttc ttgcatggtt
    33541 ggctaatgga gctcaacctt cagacacagt acgtaacatc ctttcaaaag aaggcgtatt
    33601 gaaaaaattc cacgattcta aattctcaaa ataagtttaa agtaggttga cagatggata
    33661 cgattgaaaa tctcattatt gcgattgtga aacccttaat ttcacaacca gatgccttaa
    33721 ctatcaagat tgaagataca ccagaatttt tggaatatca tttgaatctt gatcaaagcg
    33781 atgtgggtcg tgtaatcggt cgtaagggtc gcactatttc tgcgataaga acgattgtct
    33841 actctgtccc aactgaatac aaaaaagtaa gaatcgttat tgacgaaaaa taagaagggc
    33901 gggacggatg tctcgctttt ttgtgtggaa tagaagatat agtaaaatga aataataaca
    33961 ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaag taaaggtgta
    34021 ctattctagt ttcaatatac tataaaagat tgaacgttta ggcaattcca agactactta
    34081 ctcgaacatt aacagcagtc tcggactgat gaaggtctct ttatgaagtt agtggaggaa
    34141 gtcggagaag tagccgaggt tttgaatagg cgctctggtc gaaaagaagg gataggattc
    34201 gaacgaggaa cctgccatag aactggctga tatcattcac tacaccgtcg ctattgctgt
    34261 tatcaagcat attgacctaa ctagaaccat ctttgagaaa gacaaaaccg cagccgttaa
    34321 ttaccaacat aaacatgatt tggaaggatt cttgaaggga aagtagagat gttgtcccct
    34381 tcctccaact tgagaaaatc tttggaacgt gataaaataa aggataagga tttttaataa
    34441 ttcattatat agaatgagtg gatttcttta tgaagaggtt tgaagtatct acagaaattg
    34501 gtagcctctc tgttacttat caaaaacaaa agaaagtgct agtttgtcta aacggagcag
    34561 gtttgctacc aagttatgaa aatttttcac ttatacttga aaaacctcct cctacaattg
    34621 gttatttgac aattgatttt ccgaacacag gtaggagtcc gattcatgac caagctggaa
    34681 aaaatctaga taatcttgca gatgcggttt atgaagtact tgaagaatta ggaatttctg
    34741 aatatatact ttgtgcacat agttggagtg gaattttagc ttgcaaatta ctcgagaaac
    34801 caattaagcg tcagacttta gtagcaattg aaccgacaac taaaaaagtc atgtttgctg
    34861 atttttcaga aaatccttat ccagaaatgg aagagcagat gaggctgatt gacgagtgtg
    34921 gtcctgaact ttattttaag aacttaactc aagcaacatt tagtcctgaa acgaataaaa
    34981 aaatctggga attaatgcaa gaaaaaggct tagagttgga aaatcaagat ccagaatttc
    35041 agatatctgg agagattact gaggaagatt ttgagaattt gtcgatagaa tctcatgtcc
    35101 ctgtatttat tttttgtcag acttatagag aaaaagagta cagagaatca gaatattgga
    35161 cttccaatac taaactcatt ttaggaggga atcaccatta tttacaatgg tcagaatcgg
    35221 aaaaaattgc ggctattatt cgagaattgt cagaataaga tggaaaaaag gagattacag
    35281 gagacaagat gaactacttt aatgttggga aaatcgttaa tacgcaggga ttacagggtg
    35341 agatgcgagt cttgtctgtg acggattttg cagaagaacg gtttaaaaaa ggagctgagc
    35401 tggctttgtt tgatgaaaaa gatcagtttg tccaaacagt gaccatcgct agccaccgta
    35461 aacagaagaa ctttgacatt attaaattca aagatatgta ccatatcaat actatcgaaa
    35521 agtacaaggg atacagtctc aaggtcgctg aggaagattt gaatgaccta gacgatggtg
    35581 aattttacta tcacgagatt atcggtttgg aagtctatga gggtgatagc ttggttggaa
    35641 ccatcaagga aatcctgcaa ccaggtgcta atgatgtctg ggtggtcaaa cgaaaaggca
    35701 aacgtgattt gcttttacct tatatcccac cagtggttct caatgttgat attccaaata
    35761 aacgggtcga tgtggaaatc ttagaagggt tagacgatga agattgatat tttaaccctc
    35821 tttccagaga tgttttctcc actggagcac tcaatcgttg gaaaggctcg agaaaaaggg
    35881 ctcttggata tccagtatca taattttcga gaaaatgctg aaaaggcccg tcatgtagat
    35941 gatgagccct acggaggcgg tcagggcatg ttgctcagag cacaacctat tttcgattcc
    36001 tttgatgcta ttgaaaagaa aaatccgcgc gttattctcc tcgatcctgc tggaaagcag
    36061 tttgatcagg cttatgctga agatttggct caagaggaag agctaatctt tatctgtggg
    36121 cactatgagg gttatgatga gcgcattaag accttggtaa cagatgagat ttccctaggc
    36181 gactatgtcc tcactggtgg agaattggca gctatgacca tgattgatgc tacagttcgc
    36241 ctgattccag aagtgattgg caaggagtct agccaccaag atgatagttt ttcttcaggt
    36301 cttttagaat atcctcagta cacacgtccc tatgattatc gaggcatggt cgtgccagat
    36361 gtattgatga gtggccacca tgaaaagatt cgtcagtggc gattgtacga gagtttaaag
    36421 aaaacctacg agcgcagacc agatttactt gaacattatc aactgacagt agaagaagaa
    36481 aaaatgctgg cagaaatcaa agaaaacaaa gaataaagga gaaacctatg caagtaatca
    36541 aacgtaatgg cgaaattgct gaatttaatc cagataagat ttaccaagcc atcttgaagg
    36601 cagcccaaac tgtttatgtt ttgacagatg atttgcgtca aaatcttgct caagtcacta
    36661 agaaggtagt tttggattta caagaagcca aggtggaacg tgcgactatc agtatgattc
    36721 aatctatggt tgaacatcgt ttattgggcg caggttacat taccattgca gaacactata
    36781 tttcctatcg tttacaacgt gacttggaaa gaagtggtta tggagatcat atcgcagttc
    36841 atttacattt tgaacaaatt cgctaagaaa aagagtggga tgaagcaact acatctcact
    36901 ctttcttaaa tctatttttt tgggctgttt ggacagttga ggggacaaat cgcaggcgtt
    36961 gaatatcgct tatacggata atccggctca catttttgga aaaatttttc acgataattt
    37021 gctggccttg ctgatcatat ttgatgatat cacctgtaaa gcttgtctca gacaagataa
    37081 ggtgaacagc ggtttgtttc tggatagcct cttcaatagt ggctgtaagg gagttggttt
    37141 cagtctggtc aggttggtca tgtccattta aaaaatcatg tattttatct agaacttgct
    37201 ggaatttatg tctcatattg gcctcccttc ttttatatca atattatata aaattttcct
    37261 aaaatctaca agattttacg aataaactaa tgaaactaaa aaaggagaag aaaatggcag
    37321 aatttacatt tgaaatcgaa gagcacttgt tgactctttc tgaaaacgaa aaaggttgga
    37381 ccaaggaaat taaccgtgtg agctttaatg gtgcccctgc aaagtttgat attcgtgctt
    37441 ggagtccaga ccatactaaa atgggcaaag ggattactct ctcaaatgaa gaatttcaaa
    37501 cgatggtgga tgcctttaaa ggcaactaat actcttcgaa aatctcttca aaccgcatca
    37561 gctttgcctt gccgtatgta tggttactga cttcgtcagt ttcatctaca acctcaaaac
    37621 agtgttttga gcagcctgcg gctagcttcc tagtttgctc tttgattttc attgagtata
    37681 agttttcaaa ataaaaaaaa ggatattgag tcatgataac tcggtatcct tttttagtta
    37741 gtaaagtaag tctgattttt aaggcgttga agtaggggac ggctaataaa actaatagcc
    37801 agaagtttgc caaggtctgg aatgataaag ggaagaaccc ccacaacaag agctttttca
    37861 aatgccattc cagctaggaa atgcaagctg agaatcccgc cgacaaagac aagggcatca
    37921 cccaagaggt ttgcaagaaa aatcttaaca acaccactct tgctgttggt tagagaggaa
    37981 gtaagtccag agtaaacgag ataaaaccaa agatagcctg cagtagggcc aactaaagcc
    38041 tgaaaaccag ctccacctcc tgcaaagaca ggaagaccga tagcacctag aagaagatag
    38101 agtccagcag aaagtacagc ctctctcggt ctaaagacag tagcaatcaa gccgattgca
    38161 aagttttgca gagtgaaggg aacaggtcca attggaagac tgatttgtgc caaaacagca
    38221 atgagagcag ccccaatagc agggatagca taaacgtgag cttttttcaa aatagttaac
    38281 ctcttttcta atgtatagta actattatac tcatatagga gtcgatgtca accatttttt
    38341 aaaaacaagg taacaaaaac tgtaacagcc gattttcgtg actagtcaag ttggataatt
    38401 ttttgttgat tcgaaaatca ttaaaaaaga agcagacata tttatatcag cttcttttgt
    38461 ttcgattaac gcatggttac aaattcttca gatgaagttg ggtgaatcgc tacagttgcg
    38521 tcaaagtcag ccttggttgc tcccattttg atagcaacgg caaatccctg aatcatttca
    38581 tcaacgccgt agccaattcc atgaagtccg acaacttttt cttctgaacc agctgttatg
    38641 agtttgaaac gggattcttg acggttgcga gtgcaagcag agtacataga tgcaaagctt
    38701 gatttgtaaa ccttgatttg gtcttgaccg tattctttaa tagcttgctc ttctgtcaaa
    38761 ccaacagttc cgatagcagg gtgtgaaaag acaacagttg gaatagttga gtaatccatt
    38821 tttgcagtag tttttccgtt aaagagacgt tcagataggg tacgtccggc cttgattgca
    38881 actggagtca gttctttctc gcccgttaca tcacctagag catagattcc ctcaacaaca
    38941 gtattttggt attcatccac ttggataaag ccacgttcgt tcagagtcac tccagctttt
    39001 tcaagttgca agcccttaac gtttggacgg cggcctgtag cccagataac ttggctagct
    39061 gtgtgactag taccatcttc gaaatgaatg gtaatgccgt cagtagtttt ttctaacttg
    39121 acagggactt tgtgagtgtg aagtggtaag tttgttcttt ccatttcctt gaccaaacct
    39181 tcaacgatgt aggaatcaaa accacgtaaa ggacgatcgc ggcgaacaaa gagatctgtc
    39241 ttgacaccaa aagtgtggag tacgccagct aattcaacgg cgatataacc agcgcctaga
    39301 atggcaactg actctggaag ttcttcccag gcaaatacat catcagaaga gccacctagc
    39361 tcagcaccag gaatattagg aatacttgga tgggcacctg tagcaatcac gatatgttta
    39421 gcacgaatca gttcaccatt tacgcttaca gtatgagaat ctacaaattc agcatgacct
    39481 tcaatcaagt ctacaccgtt gcgtttaaaa ctaccatcat aagaagaacg agcgcgatca
    39541 atgtaggctt cacgattgcg acgtagggtt gcaaagttaa agttaagatc agtagtctta
    39601 aagccgtagt cttctccaaa ttgatggaaa gtctcagcga tttgcgcccc gtaccacatg
    39661 atttttttag gaacacaacc gacgttgaca caggttccac ctaatttctt ttcctcaata
    39721 acggctgctt tggctccatg ttcaccagca cggttcatgg tagcgattcc tccgctacct
    39781 ccaccgatag caatgatatc atattctctc attgaaaact cctttgtaat cttttaaata
    39841 gtagagtgtc ttttttgata gttatatttt attctttttt tgatttgatt gcaaaaatct
    39901 gctacgcaca aaaaattgca aaaaagcttg ccaaataagt caagatagtg tattatatat
    39961 ctagtacaat agaaaagcaa aattccgaac gattgtttaa tcctgaactg ccattatttc
    40021 catctgaact gcattgtttg ctggagggaa atttggtata atagcaaagt attgtaaaaa
    40081 agaaaaggag tttcattatg aagaaaaaga atggtaaagc taaaaagtgg caactgtatg
    40141 cagcaatcgg tgctgcgagt gtagttgtat tgggtgccgg ggggatttta ctctttagac
    40201 aaccttctca gactgctcta aaagatgagc ctactcatct tgttgttgcc aatgaaggaa
    40261 gcgtggcatc ctctgtttta ttgtcaggga cagtaacagc aaaaaatgaa caatatgttt
    40321 attttgatgc tagtaagggt gatttagatg aaatccttgt ttctgtgggc gataaggtca
    40381 gcgaagggca ggctttagtc aagtacagta gttcagaagc gcaggcggcc tatgattcag
    40441 ctagtcgagc agtagctaag gcagatcgtc atatcaatga actcaatcaa gcacgaaatg
    40501 aagccgcttc agctcaggct ccacagttac cagcgccagt aggaggagaa gatgcaacgg
    40561 tgcaaagccc aactccagtg gctggaaatt ctgttgcttc tattgatgct caattgggtg
    40621 atgcccgtga tgcgcgtgca gatgctgcag cgcaattaag caaggctcaa agtcaattgg
    40681 atgcaacaac tgttctcagt accctagagg gaactgtagt cgaagtcaat agcaatgttt
    40741 ctaaatctcc aacaggggcg agtcaagtta tggttcatat tgtcagcaat gaaaatttac
    40801 aagtcaaggg agaattgtct gagtacaatc tagccaacct ttctgtaggt caagaagtaa
    40861 gctttacttc taaagtgtat cctgataaaa aatggactgg gaaattaagc tatatttctg
    40921 actatcctaa aaacaatggt gaagcagcta gtccagcagc cgggaataat acaggttcta
    40981 aataccctta tactattgat gtgacaggcg aggttggtga tttgaaacaa ggtttttctg
    41041 tcaacattga ggttaaaagc aaaactaagg ctattcttgt tcctgttagc agtctagtaa
    41101 tggatgatag taaaaattat gtctggattg tggatgaaca acaaaaggct aaaaaagttg
    41161 aggtttcatt gggaaatgct gacgcagaaa atcaagaaat cacttctggt ttaacgaacg
    41221 gtgctaaggt catcagtaat ccaacatctt ccttggaaga aggaaaagag gtgaaggctg
    41281 atgaagcaac taattagtct aaaaaatatc ttcagaagtt accgtaatgg tgaccaagaa
    41341 ctgcaggttc tcaaaaatat caatctagaa gtgaatgagg gtgaatttgt agccatcatg
    41401 ggaccatctg ggtctggtaa gtccactctg atgaatacga ttggcatgtt ggatacacca
    41461 accagtggag aatattatct tgaaggtcaa gaagtggctg ggcttggtga aaaacaacta
    41521 gctaaggtcc gtaaccaaca aatcggtttt gtctttcagc agttctttct tctatcgaag
    41581 ctcaatgctc tgcaaaatgt agaattgccc ttgatttacg caggagtttc gtcttcaaaa
    41641 cgtcgcaagt tggctgagga atatttagac aaggttgaat tgacagaacg tagtcaccat
    41701 ttaccttcag aattatctgg tggtcaaaag caacgtgtag ccattgcgcg tgccttggta
    41761 aacaatcctt ctattatcct agcggatgaa ccgacaggag ccttggatac caaaacaggt
    41821 aaccaaatta tgcaattatt ggttgatttg aataaagaag gaaaaaccat tatcatggta
    41881 acgcatgagc ctgagattgc tgcctatgcc aaacgtcaga ttgtcattcg ggatggggtc
    41941 atttcgtctg acagtgctca gttaggaaag gaggaaaact aagatgcaga atctgaaatt
    42001 tgccttttca tctatcatgg ctcacaagat gcgttctttg cttactatga ttgggattat
    42061 tatcggtgtt tcatcagttg ttgtgattat ggctttgggt gattccctat ctcgtcaagt
    42121 caataaagat atgactaaat ctcagaaaaa tattagcgtc tttttctctc ctaaaaaaag
    42181 taaagatggg tcttttactc agaaacaatc agcttttacg gtttctggaa aggaagagga
    42241 agttcctgtt gaaccgccaa aaccgcaaga atcctgggtc caagaggcag ctaaactgaa
    42301 gggagtggat agttactatg taaccaattc aacgaatgcc atcttgacct atcaagataa
    42361 aaaggttgag aatgctaatt tgacaggtgg aaacagaact tacatggacg ctgttaagaa
    42421 tgaaattatt gcaggtcgta gtctgagaga gcaagatttc aaagagtttg caagtgtcat
    42481 tttgctagat gaggaattgt ccattagttt atttgaatct cctcaagagg ctattaacaa
    42541 ggttgtagaa gtcaatggat ttagttaccg ggtcattggg gtttatacta gtccggaggc
    42601 taaaagatca aaaatatatg ggtttggtgg cttgcctatt actaccaata tctcccttgc
    42661 tgcgaatttt aatgtagatg aaatagctaa tattgtcttt cgagtgaatg ataccagttt
    42721 aaccccaact ctgggtccag aactggcacg aaaaatgaca gagcttgcag gcttacaaca
    42781 gggagaatac caggtggcag atgagtccgt tgtatttgca gaaattcaac aatcgtttag
    42841 ttttatgacg acgattatta gttccatcgc agggatttct ctctttgttg gaggaactgg
    42901 tgtcatgaac atcatgctgg tttcggtgac agagcgcact cgtgagattg gtcttcgtaa
    42961 ggctttgggt gcaacacgtg ccaatatttt aattcagttt ttgattgaat ccatgatttt
    43021 gaccttgtta ggtggcttaa ttggcttgac aattgcaagt ggtttaactg ccttagcagg
    43081 tttgttactg caaggtttaa tagaaggtat agaagttgga gtatcaatcc cagttgccct
    43141 atttagtctt gcagtttcgg ctagtgttgg tatgattttt ggagtcttgc cagccaacaa
    43201 ggcatcgaaa cttgatccaa ttgaagccct tcgttatgaa tgagatcaac aagatggaca
    43261 ctcgtctatc ttgtttttgt atggatttcc ctatcgaaat tcattaaaaa tgtgatataa
    43321 tgaagtgtta gaaaaacagg tttcatttgc ctggaaagga aaaattatgt ctgaaaaaaa
    43381 tttttatatt acaacgccga tttactatcc atctgggaaa cttcatatcg gttctgccta
    43441 cacaactatc gcatgtgatg tcctagcacg ttacaaacgc ctgatgggct acgatgtatt
    43501 ttatctgaca ggtcttgatg aacatggtca gaaaatccag cagaaagcgg aagaagctgg
    43561 tattacacct caagcctatg ttgatggaat ggcggttgga gttaaagaac tctggcaatt
    43621 actagatatc tcatacgata aatttatccg tacaactgat gactaccatg aaaaagttgt
    43681 cgcacaggtc tttgaacgct tacttgctca agatgatatt tacttgggtg aatactctgg
    43741 ttggtattca gtatcagacg aagaattctt tacagaaagc cagctggcag aagttttccg
    43801 tgatgaagct ggaaatgtga ctggtggtat tgctccatca ggtcatgagg ttgaatgggt
    43861 ttctgaagaa tcatactttc ttcgccttag caaataccaa gaccgtttgg tcgaattttt
    43921 caaagctcat cctgaattta tcacgccaga tggtcgcctt aatgaaatgc tacgcaactt
    43981 catcgagcca ggtttggaag atttggcggt atctcgtaca acctttacat ggggagtgcc
    44041 tgtcccatca aatccaaaac acgttgtcta cgtttggatt gatgcccttc ttaactatgc
    44101 gacagctctt ggctacgctc aagacgaaca tggtaacttt gacaagttct ggaatggaac
    44161 agtcttccat atggtaggaa aagatatcct tcgcttccac tctatctact ggccaatcct
    44221 tcttatgatg ttggatgtta aattacctga tcgtttgatt gcccatggtt ggtttgtcat
    44281 gaaagacgga aaaatgtcta agtcaaaagg gaatgtcgtt taccctgaaa tgttggtaga
    44341 gcgttatgga ctagatccac ttcgttacta cctcatgcgt aaccttccag ttggttcaga
    44401 cggaaccttt actcctgaag actatgttgg ccgtatcaac tatgaattgg ctaatgacct
    44461 tgggaacctc cttaaccgta cggtttccat gattaataag tactttgatg gacaaatccc
    44521 tgcctatgta gaaggtgtga ctgaatttga tcatgttctt gctgaggttg cagaacaatc
    44581 aatcgcagac ttccatacac acatggaagc agttgactat ccacgtgcgc ttgaagcagt
    44641 ctggactctg atctctcgta ccaataaata catcgatgag accgcaccat gggtcttggc
    44701 caaggatgaa gctcttcgtg accaattggc aagtgtcatg agccacttgg cagccagcat
    44761 tcgtgtagtt gctcacttga ttgaaccatt tatgatggaa actagtcgtg cagttttgac
    44821 tcaacttggt ttggaagaag tttctagtct tgaaaacttg agtttggctg acttcccagc
    44881 agatgtgact gtagttgcca aaggaacacc tatctttcca cgtctaaata tggaagaaga
    44941 aatcgcctat atcaaggaac aaatggaagg caataaacca gcagtcgaaa aagaatggaa
    45001 tccggacgaa gttgagctca aactaaacaa ggatgaaatc aagtttgaag actttgacaa
    45061 ggttgaaatc cgtgtggcag aagtcaaaga agtgtctaaa gtagaaggtt cagataagtt
    45121 gcttcaattc tgcttggatg ctggtgatgg agaagatcgt cagattcttt caggaattgc
    45181 caaatactat ccaaatgaac aagaattggt cggcaagaaa gttcaaatcg ttgctaacct
    45241 caaaccacgt aaaatgatga aaaaatatgt cagccagggt atgattctct cagctgaaca
    45301 tgatggcaaa ttaacccttc tcacagttga tccagctgta ccaaatggaa gtgtgattgg
    45361 gtaaaagtag acaggactag ttcaggctag ttctgttttt ttatttatac tcaatgaaaa
    45421 tcaaagagca aactaggaag ctagccgcag gttgctcaaa acac
//
LOCUS       DBJKQU010000010        42622 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.010, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000010 DBJKQU010000000
VERSION     DBJKQU010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 42622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42622
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.010"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(412..804)
                     /gene="rpsI"
                     /locus_tag="ACSUUC_000659"
     CDS             complement(412..804)
                     /gene="rpsI"
                     /locus_tag="ACSUUC_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HHQ8053928.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(824..1270)
                     /gene="rplM"
                     /locus_tag="ACSUUC_000660"
     CDS             complement(824..1270)
                     /gene="rplM"
                     /locus_tag="ACSUUC_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HHQ8053929.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            1627..1944
                     /locus_tag="ACSUUC_000661"
     CDS             1627..1944
                     /locus_tag="ACSUUC_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HHQ8053930.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMYGRETILLPEEN
                     DLF"
     gene            complement(1989..2801)
                     /gene="folK"
                     /locus_tag="ACSUUC_000662"
     CDS             complement(1989..2801)
                     /gene="folK"
                     /locus_tag="ACSUUC_000662"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HHQ8053931.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYDALKK"
     gene            complement(2844..3398)
                     /gene="folE"
                     /locus_tag="ACSUUC_000663"
     CDS             complement(2844..3398)
                     /gene="folE"
                     /locus_tag="ACSUUC_000663"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HHQ8053932.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(3379..4701)
                     /locus_tag="ACSUUC_000664"
     CDS             complement(3379..4701)
                     /locus_tag="ACSUUC_000664"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HHQ8053933.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHFKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(4703..5677)
                     /gene="folP"
                     /locus_tag="ACSUUC_000665"
     CDS             complement(4703..5677)
                     /gene="folP"
                     /locus_tag="ACSUUC_000665"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HHQ8053934.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGITPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(5772..6479)
                     /locus_tag="ACSUUC_000666"
     CDS             complement(5772..6479)
                     /locus_tag="ACSUUC_000666"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHQ8053935.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(6532..7950)
                     /locus_tag="ACSUUC_000667"
     CDS             complement(6532..7950)
                     /locus_tag="ACSUUC_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HHQ8053936.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            8140..8952
                     /locus_tag="ACSUUC_000668"
     CDS             8140..8952
                     /locus_tag="ACSUUC_000668"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHQ8053937.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            9291..10310
                     /gene="adhP"
                     /locus_tag="ACSUUC_000669"
     CDS             9291..10310
                     /gene="adhP"
                     /locus_tag="ACSUUC_000669"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HHQ8053938.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            10543..11532
                     /locus_tag="ACSUUC_000670"
     CDS             10543..11532
                     /locus_tag="ACSUUC_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHQ8053939.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            11560..12363
                     /locus_tag="ACSUUC_000671"
     CDS             11560..12363
                     /locus_tag="ACSUUC_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HHQ8053940.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            12387..13298
                     /locus_tag="ACSUUC_000672"
     CDS             12387..13298
                     /locus_tag="ACSUUC_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHQ8053941.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(13354..14688)
                     /gene="pepC"
                     /locus_tag="ACSUUC_000673"
     CDS             complement(13354..14688)
                     /gene="pepC"
                     /locus_tag="ACSUUC_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HHQ8053942.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(14905..15627)
                     /locus_tag="ACSUUC_000674"
     CDS             complement(14905..15627)
                     /locus_tag="ACSUUC_000674"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HHQ8053943.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(15895..16125)
                     /locus_tag="ACSUUC_000675"
     CDS             complement(15895..16125)
                     /locus_tag="ACSUUC_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HHQ8053944.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            complement(16135..17376)
                     /locus_tag="ACSUUC_000676"
     CDS             complement(16135..17376)
                     /locus_tag="ACSUUC_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HHQ8053945.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(17398..17550)
                     /locus_tag="ACSUUC_000677"
     CDS             complement(17398..17550)
                     /locus_tag="ACSUUC_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053946.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(17571..17849)
                     /locus_tag="ACSUUC_000678"
     CDS             complement(17571..17849)
                     /locus_tag="ACSUUC_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HHQ8053947.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(17842..18105)
                     /locus_tag="ACSUUC_000679"
     CDS             complement(17842..18105)
                     /locus_tag="ACSUUC_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HHQ8053948.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(18207..22598)
                     /locus_tag="ACSUUC_000680"
     CDS             complement(18207..22598)
                     /locus_tag="ACSUUC_000680"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HHQ8053949.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(22702..24783)
                     /gene="fusA"
                     /locus_tag="ACSUUC_000681"
     CDS             complement(22702..24783)
                     /gene="fusA"
                     /locus_tag="ACSUUC_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HHQ8053950.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(25208..25678)
                     /gene="rpsG"
                     /locus_tag="ACSUUC_000682"
     CDS             complement(25208..25678)
                     /gene="rpsG"
                     /locus_tag="ACSUUC_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HHQ8053951.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(25698..26111)
                     /gene="rpsL"
                     /locus_tag="ACSUUC_000683"
     CDS             complement(25698..26111)
                     /gene="rpsL"
                     /locus_tag="ACSUUC_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HHQ8053952.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            26528..30370
                     /gene="spuA"
                     /locus_tag="ACSUUC_000684"
     CDS             26528..30370
                     /gene="spuA"
                     /locus_tag="ACSUUC_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HHQ8053953.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            complement(30470..31519)
                     /locus_tag="ACSUUC_000685"
     CDS             complement(30470..31519)
                     /locus_tag="ACSUUC_000685"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HHQ8053954.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(31790..33598)
                     /gene="glmS"
                     /locus_tag="ACSUUC_000686"
     CDS             complement(31790..33598)
                     /gene="glmS"
                     /locus_tag="ACSUUC_000686"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HHQ8053955.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(33869..35248)
                     /gene="bglA"
                     /locus_tag="ACSUUC_000687"
     CDS             complement(33869..35248)
                     /gene="bglA"
                     /locus_tag="ACSUUC_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HHQ8053956.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            complement(35348..37201)
                     /locus_tag="ACSUUC_000688"
     CDS             complement(35348..37201)
                     /locus_tag="ACSUUC_000688"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA deacylase
                     activity [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HHQ8053957.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIVDRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(37214..38473)
                     /gene="rseP"
                     /locus_tag="ACSUUC_000689"
     CDS             complement(37214..38473)
                     /gene="rseP"
                     /locus_tag="ACSUUC_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HHQ8053958.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(38495..39298)
                     /locus_tag="ACSUUC_000690"
     CDS             complement(38495..39298)
                     /locus_tag="ACSUUC_000690"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HHQ8053959.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(39307..40065)
                     /locus_tag="ACSUUC_000691"
     CDS             complement(39307..40065)
                     /locus_tag="ACSUUC_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HHQ8053960.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(40296..40868)
                     /locus_tag="ACSUUC_000692"
                     /pseudo
     CDS             complement(40296..40868)
                     /locus_tag="ACSUUC_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
     gene            complement(40849..41847)
                     /gene="ruvB"
                     /locus_tag="ACSUUC_000693"
     CDS             complement(40849..41847)
                     /gene="ruvB"
                     /locus_tag="ACSUUC_000693"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HHQ8053961.1"
                     /translation="MSRILDNEMMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            41981..42073
                     /locus_tag="ACSUUC_000694"
     CDS             41981..42073
                     /locus_tag="ACSUUC_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HHQ8053962.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
BASE COUNT        12403 a         9851 c         8223 g        12145 t
ORIGIN      
        1 cccaaactct tcacacaaga gttctaactt acccattcta tggaatcttg cattatccat
       61 aatatagtag attgaaacta gaatagtaca cctctacttc taaaacattg ttagaattcg
      121 atttgactat cctcggtttg tcctattctt atttcacctt actataaaaa taaggtaaac
      181 ttttcaaaaa aacacgaaaa aagcacccat agggcaaacc tttgagtgct ttgaaacatt
      241 gatataattg tattgattag cgttttgagg caactgacct tgtcaggttg cagccacatt
      301 tgtaagcaac taaagtcgca acaactgtgt caattgcacc aatttagtaa gaaagtataa
      361 aaaaagaaca ccccgaaagg tgctctgtat aagtatagta attctttcga attaacgttt
      421 actaaattgt gatgctttac gagctttctt aagacctggt ttcttacgtt caactttacg
      481 tgagtcacgt gtaagaagtc ctgcgcgttt caatgaatcg cggaagtctg ggtctacttg
      541 aagaagggca cgagcgatac cgtgacggat agctcctgat tgaccagcgt atccaccacc
      601 tacaacgtta acgaaaacgt cgtatgaacc tacagttgaa gtaactgcga atggttggtt
      661 gatgacaaga cgaaggtcag catgtgggat gtactcttca acatcttttt tgttaacagt
      721 gattttacca gttcctggaa caaggcgaac gcgtgcaaca gcgtttttac gacgtccagt
      781 acctgcatat tgtgcttgtg acatacttta tttgttcctt tccttagata agtcctgaaa
      841 tgtcaagaac ttctggttgt tgtgcagcat gagtgtgctc agctccaaca aatactttca
      901 acttcatacc ttgagcgcgt ccaagtgtat tgtgtggaag cataccttta actgatttct
      961 caatcaaacg tactgcattt ttagaacgaa gttcacctgc agagatttgt ttcaatccac
     1021 ctgggtggtt tgagtgagtg tagtagattt tatcagttgc ttttttacca gtcaatttaa
     1081 ctttttcagc attgataaca atcacgaagt cacctgtatc agtgtgtggt gtaaatgttg
     1141 gtttgttttt tccgcgaagt acgctagcaa ctactgcaga aagacgtcca agtggtacat
     1201 cagttgcgtc aactacgtac catttacgtt caacttggcc tggtttagcc ataaatgttg
     1261 ttttgttcat gatttctcct atatatagtt cgatttttgt ttacggtgat gggtgttcct
     1321 tcccatcgaa aagtatttgg aaggttccgg ggcctttcaa atggggtaaa caataccgcc
     1381 tactatcata ccaaatttca cccctaaaag tcaatagata tgaaaaatat ttttcggtaa
     1441 cttctcaaag taactgaaag ttatataatc aagttaattt gggaatttac ctattaactt
     1501 cggtagattt ttgggaattt ttttccttat ttttccctgt agttaaaatc cttttcaaaa
     1561 aatcaccttt tcttgatttt taatcctatt tgctgtatga taagggaaaa gaaaggggac
     1621 agagatatgg cttttaccaa tacccacatg cggtctgcta gttttggcat tgttaccagc
     1681 ttgcccgatg acatcattga ctctttttgg tatatcatcg atcatttctt aaaaaatgtc
     1741 tttgaattgg aagaagaact cgagtttcaa ttgcttaata accaaggaaa gattaccttc
     1801 cacttttcaa gtcaacacct ccctacagcc attgattttg actttaacca tcctttcgac
     1861 cctcgttatc ccccaagagt actggtttta gacatgtacg gtagagaaac tatcctcctc
     1921 ccagaagaaa atgacctatt ttaaaaactc tagccttcag ttgcaagtaa ctgaaaacta
     1981 gagtttttct attttttcaa agcatcatac aagttgcgga tcggttgttt taatgtcgga
     2041 tggataaaat gaggcgcaat ttcctgtaag gactcaagga caaaaaggcg ttccgctatg
     2101 taaggatgag gcaatatgag gtcgtctgta taaaggatct ggtcctccac aaagagcaag
     2161 tccaaatcaa tcaaacgagg tccccaatgc acttctctca cccgtcccag ctctgactca
     2221 atggctaaca aggtttctaa caagtcttgt gctggtagcc aggtttccac ctcaaccact
     2281 tgattggcaa agctatcctg ctccactcca ccccaaggct ccgtcgctaa gacactggac
     2341 tctttgagaa tatagatgcc acgagctcgc agtttgtcaa tggcttgctt caagtttgct
     2401 tgtttatctc ccatattgct tcctagggcg ataaaggctc gttgcttgcg gcgatgaatg
     2461 gttaccgagc aagtatctag tgacaaatgc accggtgccc aaggtttttt cagttccaac
     2521 ttcatttctt ggacaagagg ataagactca aaggtacgtt ccaccagttt ataggctacc
     2581 gtttcaatca aatcttcact cgtttcctga aaccaagtcg tccactgctg acataattct
     2641 ccgtaatgga cagaggctgt taaatccaag tctgtagctg ccttggtcat atcataggat
     2701 aggatggctg aaacgacaaa tttctgcccc aattctttct cactaggaaa aagaccatga
     2761 taggcaaaca tttccaaatc cttaatctgc agttgatcca taatgattcc tttctagaaa
     2821 aatccgcttg aagcggattc tttttatagc cccattaaac gataagcttg gtcgcggagg
     2881 tccttatctg tttcaaatag accacgagct actgtcgtca aggttgcagt gcctggtttt
     2941 ctaacaccac gcatactcat acacatatgt tccgcctcaa tgacaacaaa ggctccttta
     3001 gcacctagat agtccatcaa ggcatcggcc acttcgatat tcaaacgttc ttgaatttgt
     3061 ggttttttcg aataaacttc aaccgtacgg gctagcttag acaagcctgc cacacgacca
     3121 tctggaatgt aggcaatgtg cgctctacca taaaatggca agaagtggtg ttcacacatg
     3181 gtatggaaaa agatatcctt ttctaccacc atattatcgt caataatttc aaaggatttt
     3241 gacaaatgtt cctctgctgt ttgaccaaga cctgaaaaaa tctcttgata catacgggct
     3301 acacgagcag gtgtttcctg caagccctcg cgattagcgt tctctcctac agcctcgata
     3361 atcattttta cagctgcttc aatcttttgt gtatccattc tcgttcttcc tctccatcag
     3421 ataggccctc acttggctca agaaatacaa ggaacctgtg acaatcctaa ctgtttgttt
     3481 ctcttctttt ttatctgtca aattctgctc tagaaaatca tgccaatctt ggtagctgag
     3541 atttctagac ttagctgcct ctttcagcac gctttcatcc gtcgcccgac tatccgcaaa
     3601 atgtgttaga gtaagctcgg tatctggcat ggctcccagc aagtccaaca tatcctccaa
     3661 ggctttggtt ttgatacaag tgaagaggat ttccttatga taatccgcaa aacgttcttg
     3721 caaggttacc aacaaggcct tgatagcatg gggattatgg gctccatcca aaatcatcaa
     3781 gggatctctt gacacgattt ccaaacgccc tggccaactt gtttcttcca aggcttgacc
     3841 aagaaagtca ttgcttgcta gctctcgacc atcttcttga caaaaagtat caagtaaagc
     3901 tatggccatc ccagcattct ctatttggta caaaccaagc aggctagtct ggaagcgacc
     3961 ttgtctgaca gcacttgtat agtcaaagac ttcccctgtc accacacttt cttgatgacg
     4021 aacctgataa tctgtcccgt aggcaagtct cggcgcatct ttcccttccg caatgcggtc
     4081 aatcacagtc aaggcttctg gagcaatacg ccctgttacc aagggtatcc cttgtttgat
     4141 aatacctgcc ttctgctctg ctatggcctc caaggtgtca ccaagtaggg ccacatgatc
     4201 caagccaata gttgtaattc ctgtcaaaat gggctgacag acattggtac tatccaaaag
     4261 tccacccatg ccaacttcca tgatggccac atctacttgc tctgaggcaa agtagtcata
     4321 ggccagggct gtgataatct caaactcggt tgtgccctgt aaattggcga ccgcttctcc
     4381 ctccagcaaa gactgatagt ctgccatgag agcttctagc ctcgcttctg agatcgattc
     4441 cccattgatg ctaatctggt ctgtgtaatg aatgagatag ggcgagctaa acacgccaac
     4501 tctcagccct agcttttcta gcatcttttt caaaaaagca atagtcgagc ccttgccgtt
     4561 agtccctccg atatggagga ccttgagttt gaaatgggga ttgccacgca aagctaacag
     4621 ttccaccatt cgttccaatc caaaatgcgg ttgatccgtc cggtagttag caatccactg
     4681 attgttttca atttctttca tcttatttat attgttttaa atctaaattt tccgcttcat
     4741 cagccagacg aatggcagag gcaatttcaa ctgccatcct gtgactagct acgtcatgca
     4801 cgcgcaccac ttctacaccc tgtctcgcag cgatactagt tacatgagcc gaagccgtgt
     4861 cccgatttcg gaaaccaagc tctgtctcag gattgacttc aaacccactt tcttcaagga
     4921 tattgatgac aaatcgcttg cgcgacactc cgagaaagat tggatagccc ttctgatgta
     4981 gtttatccag gtcccgtaaa aggaggagat tttctttctt ggtcagacca aagccaattc
     5041 ctggatccaa caggatattt tctggtgtaa taccagcttc tgccgctctc gctagtgctc
     5101 gttcaaagaa agccaccatc aagtcttcga ttggcaatgt ttcaaagtca gctaactctt
     5161 tttctgtaaa ggtttgacca aagccaaaat gagggaagat aagcgaacta ggatgttgag
     5221 gtcgagccat gactggatta aacatgatga ctactttcgc tccagcttta gcaaccacat
     5281 gggccatttt ttcatcgccc atgagaccag tgatatcatt aactagattg gcaccagcag
     5341 ccaaagcagc ctctgccacc tgacttttcc aagtatcgat agaaataagg acatcacttt
     5401 ccttgcgaat cgctttgatc actggaacaa cacgctggat ttcctcttct atctcaacat
     5461 agctactgcc cggccgagtc gattctccgc cgatatcgag catactggct ccttctgcta
     5521 tcaatttacg agcctgctgg agtgcctgct caagagcaaa aaattgacca ccgtccgaaa
     5581 aggagtctgg ggttacattg ataattccgc aaataactgt ctttgcatga ttggctttac
     5641 ttgacatatc ggtcactccc tcaaggattt tcatcatatt atttttctat tttaccataa
     5701 aaagaaaaag atggacacga ttgcattcat ctttccctag tagaaagagg tcggttccta
     5761 cataaaaact tttacacaga aattcctaat gtccgactca taatcaccac aagagccaac
     5821 aaacagaaag caatcccatt aacaatcatg tgaagcaaga tcgacatttc caaacgttgg
     5881 gtcttgtagg ccgtccaaga tagaactgtc gacatacctc cataaatcaa taaagaaggt
     5941 aaattacttg gttgatgcaa taaagcaaac acaatcgtac cgactacaaa tcccaagttc
     6001 tccttgcctc ggaaaatctt tttaggaaca atcccacggc acaagatttc ctcacaaatt
     6061 ggagcaagca aggctagcaa gaagaagcta gaaatcagag aactattctg aaccatatcg
     6121 ttaatctgag actggttagc tgttgtcgtc tcatttgaca gttgcaacaa gatagaacca
     6181 agtatatttg acccgacaat aactaaataa ctcaagccca aacgtgccaa atctttagct
     6241 ctaaaaaaag aaaaattaaa actagctaac ttggttttac gagctcccat aataaataga
     6301 gccagaacca caattgaaag gccagtaact atcagccctg actgtagcag ggctacttct
     6361 tttaaagtca aaatagaggt aaccactagg ggaacctgat ataaaaggac ggcaagtaaa
     6421 aagaccaaaa tccagcctgc acgattcaac aattctttcc acatattttt ctctttcatc
     6481 acctatctcc tttgtattaa aaaagggggg aaatccccct gggtcattct attataaggc
     6541 catgctgatg tagttaagga taaacaaggc atccaaaatc caaatcatgg catgaacatc
     6601 tttaacttga cctttgacaa gcttagtcaa agtgtaagtc aagaaaccaa ctgcaatccc
     6661 ttgagtgata gagtagctga atcccataaa gatagatgtg aagaaggcag gaactgcttc
     6721 agacatatca tcccaatgga tatttttcaa gctaccaagc atcataatcc caacgataat
     6781 caagattgga gctgtagccg ctgttggtac gatcgctaga agtgggctaa agaagcttga
     6841 aatcgcaaaa cagatagcta caaccaaggc tgtcaaacca gtacgtccac ctgcaccgat
     6901 accagcagca gactcaacat aagtcgttac gtttgaagta cctgcaatgg caccgactgt
     6961 cgttccaatc aaatcagagt aaagagcctt atccaatttg gctgattggt gattttcacc
     7021 atttgtcgct acaataccaa ctttttcacc tgtaccgatc aaggtaccaa ttgtgtcaaa
     7081 aatatctgtc aatgagaagg caagaatggc catcagagtt tcaggcaagc gagctgtatc
     7141 tgaaaccaaa gctcccaaac cttctgaacc aagagctgca ccaaagattg tcttcaaatc
     7201 ttcaaaagct gcaccaacat ggttattagc aaaatcgata ctagacaaat caaccaaacc
     7261 aactgcaata gcaagaacag ttgttgtcaa gatagagaga ataattcccc ctttaatccc
     7321 tttgatgaca aagaagatag taatggcaag tcctgcaaga gccactaaaa cagctggatt
     7381 attaaagctg accaatcctg gaactgctga agagtttgct gcaatcgttg cttgagcttt
     7441 gtcagcccct tctcctacaa cagtatagtt gcctggatca atcgtgaatt tcaaaagtcc
     7501 agcattctta atccctacat aggcaaggaa gacaccgata ccagctgaaa tagctgagcg
     7561 aagagcattg ggaatcgatt caatgatcat tttacgaaca tttgtcaagg taataatcaa
     7621 tgaaataatc ccacagatga agaccatagc tagggcttct tgccaagaat aaccaagccc
     7681 gaatacaact gtaaaggtaa agaaggcatt gagtcccata cctggtgctt gggcataagg
     7741 taagttagca taaaaagcca tcatcaaggt acccgctact gcaccaataa tcgtcgctag
     7801 gaagacgccc tgagcaggca ttcctgtttg tgaaagtatt tgtgggttta caaagagaat
     7861 atagctcatt gcaaagaaag ttgttaaacc agcgagaacc tctgtacgaa cgtctgtacc
     7921 gttctctttt agtttaaata atttgtccat catcaatctc cttttaattt ttacgaacaa
     7981 taatagaatt atatcattta tcattcactt tttcaatgtc tttgtttgat ttgtttaaga
     8041 aattaatcca atttcatttt ttgtttggaa tctgcttttc tgcctgcttt ctgttataat
     8101 agaagacatc ttatctgaaa acacactaga aaggtccata tgacgaaaaa aattattgca
     8161 gttgacctgg atggaaccct gctcaactca gacagtcaaa tttctgactt taccaaaaga
     8221 accatcaaaa aagttgctga aaaaggccat caggttatta ttacgacagg tcgcccttac
     8281 cgtatgtcaa aagattttta ccgtgaactg ggcttagaca ctcctatgat taacttcaac
     8341 ggatccctta ctcatttacc agaccaagtt tgggattttg aaaagtgttt gactgtagac
     8401 aaaaaatatc tgctagatat ggttcaacgt tcagaggaca ttcaagccga ttttatcgct
     8461 ggagaatatc gtaaaaaatt ctacattaca aatcccaatg aagaaattgc caatcccaaa
     8521 ctatttggtg tagaagcttt ccagcctgaa gatcaattcc agcctgaatt ggtgaccaag
     8581 gaccctaact gtatcctctt gcagaccaga gccagtgaca aatatgcctt ggcaaaagaa
     8641 atgaacgcct tctaccagca tcaactttct atcaatacct ggggaggtcc gctcaatatc
     8701 cttgaatgta ccccaaaagg tgtcaacaag gcctttgctt tggactactt gctcaagata
     8761 atgaatcgtg acaaaaaaga tttgattgcc tttggagatg aacacaatga taccgaaatg
     8821 ctcgcttttg ctgggaaggg ttatgccatg aaaaatgcca atccagagct actcccttat
     8881 gcagatgagc aaatttccct taccaacgac caagatgggg ttgccaaaac cctacaagac
     8941 ttattcttat aacctatact gatactcaat gagaatcaaa gagcaaacta ggaagctagc
     9001 cgtaggttgc tcaaagcact gctttgaggt tgtagatgaa gctgacgtgg tttgaagaga
     9061 ttttcgaaga gtatgaccag cttgcaagct ggtctttgtg ctcttttcac agtctcatca
     9121 accagttaat cgattgttct actttttgtc tccaaaacct tggaaaaggc ttccttttgt
     9181 gatatacttc acatataaat acaagagagc tcgtcacact cgactctgtt gacaaaaaat
     9241 caatccagtc ccgttgtccc tgttctcggt caatatcaag gaggatagct atgaaagctg
     9301 ttgttgtaaa tccagaaagc actggtgttg ctattgaaga aaaagtactc cgtccacttg
     9361 aaactgggga agcacttgta gaagttgaat actgtggcgt ttgccacacc gacctccacg
     9421 ttgctcatgg tgactttggt caagtcccag gacgtgttct tgggcacgaa ggtatcggta
     9481 tcgttaaaga gattgctcca gatgtgaaaa gccttaaagt cggtgaccgc gtcagcgttg
     9541 cttggttctt tgaaggatgt ggcacttgcg aatactgtac aactggtcgc gaaacccttt
     9601 gccgtacagt gaaaaatgct ggctactcag tagacggtgg tatggctgaa caatgtatcg
     9661 taactgctga ctatgctgtc aaagttcctg acggacttga tccagcccaa gcttcttcta
     9721 tcacatgtgc tggagtaaca acctataaag ctatcaaaga agcaaaagtt gaaccaggcc
     9781 aatgggttgt tctttacggt gctggtggac ttggtaacct cgctgttcaa tacgctaaaa
     9841 aagtattcaa tgctcatgtt atcgcagtcg atatcaacaa tgacaaactt acccttgcaa
     9901 aagaagtagg cgctgacatt gtgattaacg gcctcgaagt tgaagatgta gctggactca
     9961 ttaaagaaaa aactgatgga ggagctcatt cagctgtcgt aactgctgtg tctaaagttg
    10021 ccttcaacca ggctgttgac tccattcgtg ctggtggtcg cgtcgtcgct gttggtcttc
    10081 cttctgaaat gatggaactc agcatcgtta aaacagtcct cgatggaatc caagtcatcg
    10141 gttctcttgt cggaactcgt aaagacttag aagaagcctt ccaatttggt gcagaaggtc
    10201 tggtagtccc agttgttcaa aaacgtccag tagaagatgc tgttgccatt ttcgacgaaa
    10261 tggaaaaagg ccaaatccaa ggacgtatgg tactcgactt cacccactaa tttaatagaa
    10321 acctatttta aaagttggaa gcttcttcca acttttttat attaaatttt aaataagaat
    10381 tcaagattac tcctcaaaaa ctcaacatat caacatacaa aaataaaaat tttttaattt
    10441 tttatgataa atagttgctt tttttatgaa aacggtttat acttaaacag tcttaaagtt
    10501 ttcttaaatg aaaactaaaa caaaaaagga ggaatgacaa taatgagtat cggaatcatt
    10561 attgcgagcc acggcgaatt tgctgcgggt attcatcagt caggatctat gatctttggt
    10621 gaacaagaaa aggttcaagt tgtgaccttt atgccaaatg aaggtcctga tgatctatac
    10681 gctaagttta ataacgctgt tgctgcattt gacgcagaag atgaggttct agttttggct
    10741 gacctttgga gtggttctcc atttaaccaa gctagtcgcg tgatgggaga aaatcctgag
    10801 cgtaagtttg ccatcatcac aggacttaac ttaccgatgt tgattcaagc ctacacagag
    10861 cgcctcatgg acgctgctgc aggtgtagaa aaagtcgctg ctaatatcat taaagaagcc
    10921 aaagatggca tcaaagctct tccagaagag ctaaatccag ttgaagaagt tgcaagcgct
    10981 gcagctgctc cagttgccca aactgctatc ccagaaggaa ctgttatcgg agacggtaaa
    11041 ttgaaaatca atcttgcccg tcttgacaca cgtctacttc acggtcaggt tgcaactgct
    11101 tggactccag attcaaaagc aaatcgtatc atcgttgctt cagataacgt ggctaaagac
    11161 gaccttcgta aagaattgat taaacaagca gctccaggta atgtcaaggc taacgtggtt
    11221 ccaattcaaa aactgattga gatttcaaaa gacccacgtt ttggagaaac acatgccctt
    11281 atcttgtttg aaacacctca agatgccctt cgtgccatcg aaggcggcgt gccaatcaag
    11341 actcttaacg ttggttctat ggctcactca acaggtaaaa cattggtcaa taccgttttg
    11401 tctatggaca aagaagatgt tgctacattt gaaaaaatgc gtgacttggg tgttgaattt
    11461 gatgtccgta aagtaccaaa tgattctaaa aaagatttgt ttgacttgat taacaaagcc
    11521 aatgtcaaat aagccattat ttatgaaagg attttaaaca tgtctattat ttctatggtt
    11581 ttagtagtcg ttgtagcctt ctttgcaggt cttgaaggca tcctcgacca gttccaattt
    11641 caccaaccac ttgtagcctg tacccttatt gggcttgtaa caggtcactt ggaagcaggg
    11701 attatcctcg gtggatcgct tcaaatgatt gcccttggtt ggtcaaatat cggtgctgct
    11761 atcgctcctg atgctgcact tgcttctgtc gctgctgcca ttatcatggt tcttggtggt
    11821 gactttacca agactggtat cggtgttgcc caagcggttg ctatccctct tgccgtagct
    11881 ggtctattct taactatgat tgttcgtaca atttcagttg gattggttca cactgctgat
    11941 gctgccgcta aaaaaggtga cttcggcgct gtggagcgtg ctcatttcat tgcgctactt
    12001 ttccaaggac ttcgtatcgc gcttcctgca gctcttctcc ttatggtacc aactgaaact
    12061 gtacaaagta tccttagtgc catgccagac tggctcaaag atggtatggc tatcggtggt
    12121 ggtatggtcg ttgccgttgg ttacgccatg gttatcaaca tgatggcaac tcgtgaagta
    12181 tggccattct tcgctcttgg tttcgttctt gctgctgtgt cagatattac tctaatcgga
    12241 ttcggtgcta tcggtgttgc tatcgctctt atctaccttc acctttctaa aactggtgga
    12301 aatggtggcg gaggagccgc aacttctaac gacccaatcg gcgatatcct agaagactac
    12361 taagataaga aaggactgaa aacatcatga ctgaaaaact tcaattaact aaatcagatc
    12421 gtaaaaaagt ttggtggcgt tcaaccttct tacaagggtc ttggaacttt gaacggatgc
    12481 aaaacttggg ctgggcttat acactcattc cagctatcaa aaaactctat actaaaaaag
    12541 aagatcaaat cgctgctctt gagcgtcacc ttgagttctt caacactcat ccatacgtag
    12601 ctgctccagt catgggggtt actcttgcgc ttgaagaaga acgtgctaac ggtgtggaaa
    12661 tcgatgacgc tgctatccaa ggggttaaaa tcggtatgat gggacctctt gctggtatcg
    12721 gtgacccagt attctggttt acagtacgcc caatccttgg atctctcggt gcttcacttg
    12781 cccttactgg caatatcttg gggccactcc tcttctttgt tgcatggaac ttgattcgta
    12841 tgtcattctt gtggtatgtt caagagattg gatacaaggc tggatcagaa atcactaaag
    12901 atatgtctgg tggtatcctt caagatatca ctaaaggagc ttctatcctt gggatgttca
    12961 ttcttgctgt ccttgttcaa cgctgggtaa atattaaatt tgctttcgat gtttctaaag
    13021 ttcaactaga tgaaaaggct tatatccatt gggataaatt gccagaaggg tctaaaggta
    13081 tccaagaagc attcgcacaa gtaggacaag gattgtctca aactcctgaa aaagttacta
    13141 ctttccaaca aaacttggat atgttgattc ctggattatc aggactactc cttactttac
    13201 tttgcatgta cttacttaag aaaaaagtat ctccaatcac tattatcctt gccctcttcg
    13261 cagtgggtat tgtggcacat gttcttcaca tcatgtaatc aagcaactaa aaaggaacca
    13321 ggttctaaaa tctgattcct tttttctatg cttttattca gccaaggctc ccattggatc
    13381 ccatggtgca agtacgattg gttctgctcc ataggcagct tgttcttctg ctgtcagcaa
    13441 ttccttacga acaacgattt ggtatgtgta ttcgtccatc caagcgtctg aggcaacaaa
    13501 gtaaccatct gtaccgacct tgtctcccca tgagttttca accttccact tggttgattt
    13561 accattttcg tccaagtcaa cacctgtcaa gaccatggcg tgggtcatca agctttcgct
    13621 atagtccaaa cgtccagcct tgtcttgagt aagtttaatg tccatgcttg attcaaagtc
    13681 ataaacatct gtcgcaagga tgccagcctt acggttgctg agctggccga catcagaacc
    13741 aaaccaaaca gtctcacctg cttgcatttg ggcaatcgcc aattctttca agcgctccat
    13801 tggaacgttg atgtagcgaa ctgcacggct accaaccaca ttccccaaca tctcaactgt
    13861 gtaagatttt ccgtaaggtt tatcagcagt tggagcattg ataacagaaa cgtagtcttc
    13921 taaaggaaga ttgacatatt tcttgtaaaa ctcttgtggt gtgattcctt tttcactttt
    13981 atagttgtta tctttatcgc gataagcaaa gtcaaacttg cgtggtggaa gtcctaatga
    14041 catagcaaga aagttaaaga tttcttgcaa gaggtcttct ttcttagctt gaacagtcgc
    14101 ttgatctgca ccagaaacaa gcaaatcacg caagatttga gcatcttgac gaagcaattt
    14161 attaaggatc gcatttagct cacgactgct gctagatgaa acagactcag gataaactga
    14221 cttaggcacg acaccgtatt tttcaaagag ggaaacgacc atatcccatt gaccgccatc
    14281 ttgttgaggt gtttggagta agaagctaac cttgcggcta gtcaattctt ggtctgaagt
    14341 cgcaatgact tgctccaaga accagtttga tttctcatac ttatcccaga agaaagtgtg
    14401 ggcttgtgac aactcaaagt tctccaattt gtattgcgag atgagtttgt ggcggaaggt
    14461 gttgagagcc gcaaacatcc agcaacgacc agacgctttc tggttagtga ccttgtcctt
    14521 ggttaaatcc aatgagaaaa caggtgtgtt gtctacatgg ctttggcgac attccagagc
    14581 tgcaaaaatt ccgttgtggc tggcagcatt ttcaatcgct tggtatttta catttgcttc
    14641 atagttggca aatagtttat cagtaaatga ttcttgaatc gcgttcatag attcctcctt
    14701 ttattctaca gtctattata actcttttca caaaggaagc aactaaaaaa cataaaaggc
    14761 gaggacattg tccctcacct ttttcgaatt tatactcttc gaaaatctct tcaaaccacg
    14821 tcaacgtcgc cttgccgtac tcaagtacag cctgcggcta gtttcctagt ttgctctttg
    14881 attttcattg agtattaaac taaattaaat aatattagcg cggagaattt ctaattcttc
    14941 cttggtcaag cgacgccatt cccctcgttc caggttctca tctaatacta aagttcccat
    15001 agtcaatcgt tgcaagtcca ccacttcctt gccacagtag cccaccatac gcttgatctg
    15061 atgaaacttc ccttctgcaa tggtcacacg gatttggctc tgattctttt ctgcatctgt
    15121 ggaaagaatc tccagtctag cgggctgaca ggtaaagtct ttgagcggaa tgcccttgat
    15181 aaatgtctcc acatcttctt gggtcataat tcccttgacc tgagcctgat aagtcttgtc
    15241 cacatgacgc ttgggcgaaa gaagaacatg agccagctga ccattattgg tcaagagcaa
    15301 aagaccatgc gtgtcaatat ccaagcgtcc tactggaaaa acttccttac tccgcgccaa
    15361 gtcatccaac aagtccagaa cggttctgtg cttgggatcc tcagtcgctg agataactcc
    15421 tttgggcttg ttcatcatgt agtagacaaa ctcttcatac tccaacactt gcccatcaaa
    15481 gcgaatctca tctatttttt catcaatctg caatttagct gatttttctt ttttaccatt
    15541 tacagtcacg cgcccagcct tgagcaagtt tttgacctca gtccgacttc ccaccgcaca
    15601 ggcaactaaa aatttatcta atctcataga actattatat catatcaaaa ggaggctagt
    15661 acaatgacca acctcctttt cgtttcatac tcttcaaaaa tctcttcaaa ccgcgtcaac
    15721 gtcgccttgc cgtatatatg ttactgactt cgtcagttct atctgcaacc tcaaaacagt
    15781 gtttttagct gacttcgtca gttctatctg caacctcaaa gcagtgcttt gagcaacctg
    15841 cggctagttt cctagtttgc tctttgattt tcattgagta tcagatttag gaaattaact
    15901 tcctcgtctc caaaaaatag ctaaaacaat catggctcct aaaatcgctg ggataatagc
    15961 tgttcctgat aaaactggcc cccaagttcc aaagagcaag tgacctagaa aggctccgat
    16021 ccaaccgaga aacatttttc caaaacatcc cattcgctct ccacgattgg tcatagcacc
    16081 tgctaaaaat cccactagga gaccaacgaa catacttcct aacatattat ctccttaatt
    16141 tgcccaattc ccattacgga aaagaggtac ccgcgttcca tcctcacgaa taccatcgat
    16201 atccatttgg ttagaaccaa tcataaagtc tacgtgaaca tctgaacggt taagccctgc
    16261 agcttcaagc tcctcttcgc tcatctccgc tccatcaaca acgctagtcg cataggctgc
    16321 accgatagcc aagtggtttg acgcattttc atcgaaaagg gtgttaaaaa aggtaatgcc
    16381 tgactgagaa attggacttg gatctggtac caaggcacat tcacccaagg cacgcgcacc
    16441 cgcattttta aagacaaggt ctttcataac ctgatcaccc ttctcagcag tgatatctac
    16501 gatttgtcca tccttaaagg tcaccttaat gccttcaatg atatttccgt tgtagctaag
    16561 cggttttgta gaagtgacat aaccatctgc acgacggaag tcaggcgctg tgaagacctc
    16621 ttctgtcggc atatttggca agaattcttc gccctgtgca ttgacagcac cagctgattc
    16681 ccaaacgtgg ttctttggca aaccaagtgt taaatctgtt cctggcgctg tgtagtgaag
    16741 ggctgaaaat tgctccttat taagcatatc ggccttgctc ttgagaatgg ctgcatgttc
    16801 ctcccaagcc ttaacaggat ctgcttcgta gacacgacaa gttttgaaga tttgatccca
    16861 aaggaaatca actgcttctt cgtcgctcgc agcatttggg aagactttct tagcccactc
    16921 aagtccagca gcggctgcta cagtccagct aaccttgtta gattgagttg cgatacgcat
    16981 aggcttcatg gcaagtccca tagctttagc agaagctgaa agcttgtcag cgtccactcc
    17041 gttcaaggca cctggatcag atgaacgaac cccaagacgg ctagccttgt tctccaaaag
    17101 atagttcatc tcagcaatct tgtattctgg cacattgtcc aaacgctcca tcggggcatg
    17161 gaggaatttc tcacggttaa tcacatcatc tgtccactga acgatgacct catgcgcacc
    17221 caaggcataa gcttctttca cgattagatg tgccaattca cgttgctcca catcaataga
    17281 gagagccaaa gtgtgaccag gttgcacgtt aattccgttc gcaaccaaca atttcgcata
    17341 ttttcctaga ttttctttaa aatttggtaa aaccattctg ttttctcttt tctattttta
    17401 tttttctttc aaagcagaaa agattcctgc taaagcaata gcacctgaca agagtgctgt
    17461 cgatagaaga attgtacgat cagcaagttc taattgatat tcaaatacct tcttagccgg
    17521 cttatcttcc gcaaatattc ttagtttcat gagaaccccc ttaaaataga ttaaaataaa
    17581 tcactgtgac tgcctgtcct cagcaaattt aaaatcaatt ccgacttgtc tactttataa
    17641 accaaaagcc aatctggctg ggtatggcat tcacgaactc cttgaaaatg cttggatgcc
    17701 gtcaatgaat gatcacgata tctggcagga tgttcttttt cttgaaccag aaaattcaaa
    17761 acttcttcta ataattctgc cttcaaacca cgcttcatag ccaacttaaa atctttttta
    17821 aactgtttat gataacgaat cttaagcacg taagtcctcc atcaaatctg agactgattc
    17881 aaaagactgg ctcatattac gattttggtc taaatccgtt aacgcttgga gcaacttccg
    17941 attttcgtct agtctaacat caaaaggtaa tccctgatat tgaattgcct gacgaaggaa
    18001 aatattaata gctgttgtca tatccattcc cagattacta aacacctgtt gggcctgctc
    18061 cttaacctca ctatccagac ggatgcttat actcatcttt gacatactct caccctcttt
    18121 ccatagacta ttttaacaaa aaagaaagct aatgtaaatc tattggatat acgttagcct
    18181 cttttaatag attattaagc aattttttaa aacaactcat caaacaaact caactggtta
    18241 tcctctggca tatttccaag aatacccatc tcatccatct tttcaaccaa ggttgatgag
    18301 agtccaccac gcttgcgtag ttctgtttta gagaggaatt ctccctcttc acgcgcccgc
    18361 accagttgct tggcaacgtt ctctcccaga ccatccattg ctacaaatgg tgggataagg
    18421 gtatccccgt cgatgaggaa ctctgtcgcc tgactacggt agagatctaa tttaccaaac
    18481 ttgaaacctc gttcccacat ctcattgaca atctcaagag ttgtatagag atcgatttcc
    18541 acattagagg cttcattgtt cttccgtttt tcagagattt cttccattct gcgcttgatg
    18601 acctccaagc ccgcacccat ggtcttgata tcaaaagcct tagcacgaat ggagaagtaa
    18661 gcacagtagt aataaatagg atggtgaacc ttgaagtaag ctacacgcaa ggccatcata
    18721 acgtaggctg ccgcatgggc cttagggaac atgtacttaa ttttcccaca ggattcgata
    18781 taccactctg gcaccttatt agccttcatg gcttcgatat agccatttct ctcctcttct
    18841 gaaatcttta gccacaaacc cttacgtacc cgttccataa tggtaaaggc catcttaggt
    18901 tccagacccg catgcatgag gtaaaccatg atgtcgtccc gacaaccgat aacagtcgat
    18961 aggtccgcta ttccttgctt aatcagatcc tgagcattcc ccaaccaaac gtcagtaccg
    19021 tgggacagac cagacagctg aagcaattcc gcaaaggttg tcggatgggt ttcgtctacc
    19081 attccacgta cgaaatttgt tccaaactct ggaatcccca acatacccgt aggcgttcca
    19141 atttgttcag gtgttacccc tagtacatca gtcccagaaa agagtgccat cacgccttcg
    19201 tcatccatag gaattttatt agggtcaata ccagacaaat cctgaagttt tcgaatcatg
    19261 gtcggatcat catgtcccag tacatcgagt ttgaggacgt tctcatcgat atcgtggaag
    19321 ttaaagtgag tggtctgcca ttcagccgtg acatcatctg ctggatactg gacaggcgta
    19381 aaatcgtaga catccatgta gttcggaata acaacgattc cccccgggtg ttggcctgtt
    19441 gtccgcttga cacccgccgc tccttgagcg aggcgttcta cttctgcatc acgataaaac
    19501 ttgccataat ctcgctcgta acccttgaca aatccatagg cagtcttggc agctaccgta
    19561 ccaaccgttc ccgcacggaa ggcatattct tcaccaaaga tatcacgcac atccaagtgg
    19621 gcgctaggct gatcttctcc cgagaagttc aagtcaatat caggaacctt atccccatca
    19681 aaaccaagga aggtctcaaa cggaatatcc tgtccgtttt tactgagttt gtgaccacag
    19741 tttggacagt ccttatgggg catatcaaat cctgaaccgt acgaaccatc tgtgataaac
    19801 tcactgtact gacactgacc acagacatag tgaggagaga gaggattgac ctccgtaatc
    19861 ccaatcatgg tcgcaacgaa actagatccg acagacccac gagaaccaac caaataaccc
    19921 cgttcattag aacgttgcac cagcatctgc gatgccagat aaatcacagc aaatccattc
    19981 cccagtatgg atgttaattc tttttcaatc cgcaaatcaa caatatctgg cagcggattt
    20041 ccataaatct caaaagcttt cttataggtc aactcagcaa ctgtttcttc agccttgtcg
    20101 atgaaaggcg tatacaagtc acccttaacg acttcaacgg attcaaatat ttctgccaag
    20161 gcattggtgt tttcaataac cagtttacga gccagttcct ctcccaaaaa ggcaaattca
    20221 tccaacatct cattagtcgt tcgaaaatga gcctttggaa gtggtgctgg ttgggcatgt
    20281 tcaccatgac cgatagttcg attaatcatc gcaccctgtc ccaaactacg gacgataatt
    20341 tcacgataaa tctcttcttc cggttcgata tagtgaacat ttcccgtagc cagaacaggc
    20401 ttgccaaggc ggtctccaac ctctatcaaa ctcttgataa tggtctggag ttcctccata
    20461 tccttgacct gctctttggc aatcaagggt gcatagatag ccggtggcat gacctcgata
    20521 aaatcataat acttggccac ctcaaccgcc gcatccacac cttgagaaac gaccacgtca
    20581 aaaacttcac cctctgaaca ggctgaacct aaaatcaagc cctctcgatg ggcatctaga
    20641 accgttctcg gaatccgtgg cactccttca aaatacttgg tattagacaa ggaaaccagc
    20701 ttaaagatat tttttagacc tacctgattc ttgacataga tggtcgcatg cttgatccga
    20761 gcttttttgt aagaatctgg actgattaga tcaatgttga gtctagctaa atcggtcaca
    20821 ccatgttttt ctgctacctc tttgataaag atgaaaagca gacgaccagt cgcttccgca
    20881 tcgtagttgg ccatgtggtg atgttccaag gccacaccaa aacgcttggt caaaggcccc
    20941 aaaccatggc gtttatactc aggatagagg tttctagcaa actccagcgt atcaataact
    21001 ggctgactaa tctttggaag atcatgccgc tcataattag cattcataaa gccaacgtca
    21061 aaggtagcat tgtgggcaac taggaccgta tccttgcaaa attcttggaa ttcttgcaaa
    21121 acttgttcta gtggtttggc atttttgaca tgatcatctg taattccagt taactctgta
    21181 gtaaaggctg acaagggatg cccaggattg ataaattcat caaattcagc aataacattc
    21241 cccttgtaca tcttagaagc cgcaacctga atcaagtcat tatagatagc tgaaagtccc
    21301 gtcgtttcca cgtcaaagac cacgtaggtt gcttctgaca agtccatctc cacttcgtta
    21361 tagacgatag ggacacggtc ctccacgata ttggcttcca tcccatagat cagctggatt
    21421 cccgctttct tagccgcctt atagccatgt ggaaaggact ggacattccc atggtccgtg
    21481 atagcaaccg ccttgtgtcc ccacttagca gctgttgcaa caatctcttc gacctctggc
    21541 aaagcatcca tagtcgacat gttagtatga gcatgaaact caacccgacg ctcaccttct
    21601 ggcatcaaat ccttccgctc atagtgaaca acttcctgca gatcctgtac gttcatagtc
    21661 aaatcgcgtg tgaagttatt catctccaca ttccctcgaa ctcggagcca agaattcttc
    21721 ttgatgaggt caaacttctg ggcctcttcc tcgtttttaa cccacttttg catagaaaaa
    21781 cttgaagtat agtccgtcat tttaaagttg attaaaacac gacctgttct agtcactttt
    21841 tgctccacat caaaaacaac cccttcaaat accagacgat tttcctctgt cgtcacttcg
    21901 atcataggag taatctccgc cttatccagc ttgggtttag ctgcagcttt tttcgcttga
    21961 aaatcaaagg ctggtttctc ttccgctgga ggaggtgcca tctgctccag ttgttccata
    22021 gcacggagcg cttcctcatt ggcagcttga acaatctgct cattttcagc atgaaaggcc
    22081 tcttcctgct cttgggtcag gacatcattc ttctcgactt gacagttaaa agttggaaaa
    22141 ccaaactttt caagttgttt ggctaaatta ggaagatgat tcttcttaaa atgttcctta
    22201 tcaatcgctt cagatccttc aataaatagc tgattaccct cagcacgaac ttgcaaattt
    22261 tgataaaggg acttaaaacc ttgactagca catggacctt cagagaaagc ctccctatag
    22321 taggactgca agagctgatt tgaaaattct tgagaccgag ccttaatttc aaaaacagct
    22381 ttattgcctg tcttagaaaa ttcttcgctc aaacctttct ttaattctaa aaagatttca
    22441 atcggtaaaa tattagaaaa tacgaaatga aactcccata ccttactaat tttatgaacc
    22501 acaactcgct caatattggc ctgtgctaaa gcaggagcct gtctcatttc agcaggcatc
    22561 cccaattgat tcatcaaaat ttcaaaacta tttgacattc attttcctca cattattctt
    22621 ctactatttt accatattta gaggtatttt ctaaagacaa aaggaagcca ctaagtgact
    22681 tccttctaga gtgaggacgg attagtcttc acctttattt ttcttaataa tttcttcttg
    22741 tactgactta ggtacatctt cgtagtggtc aaataccatc atgaatgtac cacgtccttg
    22801 agatgcagaa cgaagaactg ttgcgtaacc gaacatttca gcaagtggaa cgtaagcacg
    22861 aacgatttgg ctgttaccgt gtgcttccat accatctaca cgtccacgac gagcagttac
    22921 gtgacccata acatcaccaa ggttttcttc tggaacagtg attgttacaa gcatcattgg
    22981 ttcaaggata gctggttgtg ctgatttagc agcttcttta agggaaagtg aagccgcaat
    23041 cttgaaggca gtttcagatg agtcgacatc gtgatatgaa ccatcataaa gcttagcttt
    23101 aacgtcaacc attgggtaac ctgcaagaac accgttagcc atagattcta ccaaaccttt
    23161 ttcaaccgct gggataaatt cacgaggaac cacaccaccg acgattgcgt tttcgaattc
    23221 gaatccttta ccttcttcgt ttggagtaaa ttcaatccat acatcaccga attgaccttt
    23281 accaccagac tgacgtttga agaatccacg tgcttgagta gaagcgcgga atgtttcacg
    23341 gtaagatact tgaggagcac ctacgttcgc ttcaactttg aactcacgac gcatacgatc
    23401 aacaaggacg tcaaggtgaa gttcacccat acctgagata actgtttcac cagtttcaac
    23461 gtttgtttca acgcggaatg ttggatcttc ttcagccaat ttttgaaggg cgatacccat
    23521 cttgtcttgg tcagctttag attttggctc aaccatcaat tggataactg gttctggaac
    23581 gttgattgac tcaaggatga ttttagcttt ttcatctgtc aatgagtcac cagttgtagt
    23641 atctttcaaa ccaacggcag cagcgatatc acctgagtaa acagtgtcga tttcttgacg
    23701 gctgttagcg tgcatttgaa ggatacgtcc gatacgttca cgtttacctt tagaagtatt
    23761 caatacgtat gaacctgatt gaagaacacc tgagtaaaca cggaagaatg tcaaacgacc
    23821 tacgaatggg tcagtcatga tcttgaaggc aagagctgca aatggctctt cgtcagatgc
    23881 tggacgaatt tcttcagcgt ctgtatctgg gttaatacct ttgattgctg ggatgtcaag
    23941 tgggcttgga aggtagtcga taaccgcatc aagcatcaat tgaacacctt tgtttttgaa
    24001 ggctgaacca cacaatactg ggaagaattc aacgttgata gtcgctttac ggataccagc
    24061 tttcaattct tcgttagtga tttcttcacc ttcgaggtat ttcatcatca attcttcgtc
    24121 agtttcagca actgcttcaa tcaatttttc acggtattct tgagcttggt caaggtattc
    24181 agctgggatg tcttcttcaa ggatatccgt accaaggtcg ttagtataga tttcagcttt
    24241 catcttgatc aagtcaatga taccacggaa gtcatcttca gaaccgattg gcaattggat
    24301 tgggtgtgca tttgcttgaa gacgatcgtg aagtgtgctt acagagtaaa ggaagtcagc
    24361 accgattttg tccattttgt tggcaaatac gatacgtgga actccgtact cagttgcttg
    24421 acgccaaact gtttcagttt gaggctcaac acctgattgt gagtcaagaa cggtaaccgc
    24481 accatccaat acacgaagag aacgttgtac ttcgattgtg aagtccacgt gtcctggtgt
    24541 gtcgatgatg tttacgcggt ggttgttcca ttgagctgtc gtcgcagcag atgtgatcgt
    24601 gataccacgt tcttgctctt gctccatcca gtccatttgt gacgcacctt cgtgagtttc
    24661 accgattttg tggattttac cagtgtagta aagaatacgc tcagtagttg ttgttttacc
    24721 ggcatcgacg tgagccatga taccgatatt acgagttttt tcaagtgaaa attcgcgtgc
    24781 catgaggttt gtttctccta tttatttttg atttctattc tattataaca cgattttaat
    24841 aaaaacggat aggcaggacc tacccgttct caatgttttc atgctattgt tggtttcaac
    24901 ttacgagatg gtaagctgag ttatagctaa tactaatcga tttagctaat ttgaacccgg
    24961 gctaaagtta gttagccgat gtgagctgga acgggatgct gcgtgaaaaa gataaaactc
    25021 cttgtattcg tcgaatactg cgtcagtttc ctatttttac cttgcatcct taccgttcct
    25081 agcatcatga tttagttgag ctcaagctaa aagtctggag aaaaagatga atctcattgg
    25141 ttgcaaccgc aacctgcttc gattccctat tttctctggg actttcttaa cgctttcgca
    25201 tcctatctta ccaacggaag tgtgcgaatg cacggttagc ttcagccata cggtgagtat
    25261 cttcacgttt cttaactgct gcaccagtgt tgttagcagc atccaagatt tcttttgcaa
    25321 gacggtcttg cattgtgtgt tcaccacgaa gacgagcgat tgttaccaac caacgaagtc
    25381 caagtgttgt acgacgttct ggacgaactt caactgggac ttggtagtta gaaccaccaa
    25441 cacgacgtgc acgtacttca agtacaggca tgatgttttc catagctgtt tcaaatactt
    25501 caagtgcatc gttgccagta gcttctttga tttgctcaaa agcaccgtaa acgattgaag
    25561 cagcagtacc acgtttacca tcaagcataa cgcggttgat aagacgagta actagttgtg
    25621 aattgtatag cggatctggc aatacgtcac gttttggagc tctattttta cgactcattt
    25681 ctctttatcc cctttcctta tgcttttgga cgtttagtac cgtatttaga acggccttgt
    25741 ttacgatcgt taacacctgc agtatcaagt gcaccacgga cgatatggta acgtacccct
    25801 ggaaggtctt ttacacgtcc accgcgaaga agcaccacgc tgtgctcttg caagttgtgt
    25861 ccgatacctg ggatgtaggc agtaacttcg ataaggttgc tcaaacgtac acgagcgaat
    25921 ttacgaaggg ctgagttagg ttttttaggt gtcattgttc caacacgagt tgcaacacca
    25981 cgtttttgtg gtgaagaaac gtttgtttga acttttttat gactattgta accaacgttc
    26041 aaagctggtg atttagattt ttctactttt gatttacgcg gtttgcgaac caattggtta
    26101 attgtaggca tctacattct cctgtgtttt tttatttttg gtgatgatac acttggtgac
    26161 agatatcatc tgtgtgtact tttgcaacat ttgtcagcac gtccctgtac actcttgaga
    26221 gaccaaaagt aaaaagtacc gtctattatt gtaacaaaat tttcccttgc ttgtcaagat
    26281 atttttcttt tttattggta atgttagaga tcaatttctg aataaaaata gctgagaaca
    26341 catcatcttc ctaataacac ggcttggctt acgtgacatt tttatctccg tcatttatac
    26401 tgatatataa aatagtacgg aaaacttctc aaaagtaaga atttctttca caaatcaaag
    26461 aaaacgcttg catattgttt tactacatgc tatactgata tagaaattta ttgattggag
    26521 aatcattatg agaaaaacac catctcacac tgagaaaaaa atggtctaca gcatccgttc
    26581 cctcaaaaat ggaactggtt ctgtccttat cggcgcaagc cttgtcttgc ttgccatggc
    26641 tacaccaact atctcatccg acgaaagtac accaaccact aacgaaccca acaacagaaa
    26701 tacaaccacc cttgcccaac ctcttactga tacagcagct ggctctggta agaacgaaag
    26761 tgatatttct tcacctggaa atgcaaacgc ttccctagag aaaacagaag aaaaacctgc
    26821 tgcaagccca gccgatccag caccacaaac tggacaagat cgttcaagtg agccaactac
    26881 ttctactagt ccagtaacaa ctgaaactaa ggcagaagag cccatcgaag ataactactt
    26941 ccgtatccat gtcaaaaaac ttcctgaaga aaacaaggat gctcaaggac tatggacttg
    27001 ggacgatgtt gaaaaaccat ctgaaaactg gccaaacgga gctttgtcct tcaaggatgc
    27061 caagaaagat gactacggct attacctaga tgtcaaatta aagggagaac aagccaagaa
    27121 aattagcttc ctcatcaaca atacagctgg aaaaaatcta accggcgata aatctgtaga
    27181 aaaactagtt ccaaaaatga acgaagcttg gttagaccaa gattacaagg ttttctctta
    27241 cgagccacag cctgcaggaa ctgttcgcgt caactactac cgcacagatg gcaactatga
    27301 caagaaatct ctctggtact ggggagatgt gaaaaatcca agtagcgctc aatggcctga
    27361 cggaacagac tttacggcta caggcaaata tggccgctat atcgacattc ctcttaatga
    27421 agccgcaaga gaatttggat ttttattact agatgagagc aaacaaggag acgacgtgaa
    27481 aatccgtaaa gaaaattata agttcacaga tttgaaaaat catagccaaa ttttcctaaa
    27541 agacgatgat gaatcgattt acacaaatcc atactatgtc catgatatcc gtatgacagg
    27601 agcccaacac gtaggcactt ctagcattga aagtagcttt tcaacacttg tcggtgctaa
    27661 aaaagaagat atcctcaaac actccaacat cactaatcac ctaggaaaca aggtaactat
    27721 taccgatgtt gcaatcgatg aagctggtaa gaaagtgacc tacagcggag atttctctga
    27781 cacaaaacat ccttatactg ttagctacaa ttccgaccaa ttcactacca aaacaagctg
    27841 gcgcctgaaa gatgagacat acagctatga tggcaaactg ggagctgacc taaaagaaga
    27901 aggaaaacaa gttgatttga ccctttggtc accaagtgct gataaggttt ctgttgttgt
    27961 ctacgacaag aatgaccctg acaaagtagt tggaactgtc gctcttgaaa aaggggaaag
    28021 aggaacttgg aaacaaactc tagacagcac aaacaaactc ggaatcacag atttcactgg
    28081 ctactattat caataccaaa tcgagcgtca aggtaaaact gttcttgcac tcgatcctta
    28141 cgctaaatct cttgctgctt ggaatagcga cgattccaag attgacgatg cccataaagt
    28201 ggctaaagcc gcctttgtag atccagctaa actcggacct caagacttga cttatggtaa
    28261 gattcacaat ttcaagactc gtgaagacgc cgttatctac gaagctcatg tgcgtgattt
    28321 cacttcagat cctgccattg caaaagactt gaccaaacca tttgggactt ttgaagcctt
    28381 cattgaaaaa ctagactatc tcaaagactt gggtgtaacc catatccagc tccttccagt
    28441 cttgtcttac tactttgtca atgaattgaa aaaccatgaa cgcttgtctg actacgcttc
    28501 aagcaacagc aactacaact ggggatatga ccctcaaaac tacttctcct tgactggtat
    28561 gtactcaagc gatcctaaga atccagaaaa acgaatcgca gaatttaaaa acctcatcaa
    28621 cgaaatccac aaacgtggta tgggagctat cctagatgtc gtttataacc acacagccaa
    28681 agtcgatctc tttgaagatt tggaaccaaa ctactaccac tttatggatg ccgatggcac
    28741 acctcgaact agctttggtg gtggacgctt ggggacaacc caccatatga ccaaacggct
    28801 cctaattgac tctatcaaat acctagttga tacctacaaa gtggatggct tccgtttcga
    28861 tatgatggga gaccatgacg ccgcttctat cgaagaagct tacaaggctg cacgcgccct
    28921 caatccaaac ctcatcatgc ttggtgaagg ttggagaacc tatgccggtg atgaaaacat
    28981 gcctactaaa gctgctgacc aagattggat gaaacatacc gatactgtcg ctgtcttttc
    29041 agatgacatc cgtaacaacc tcaaatctgg ttatccaaac gaaggtcaac ctgcctttat
    29101 cacaggtggc aagcgtgatg tcaacaccat ctttaaaaat ctcattgctc aaccaactaa
    29161 ctttgaagct gacagccctg gagatgtcat ccaatacatc gcagcccatg ataacttgac
    29221 cctctttgac atcattgccc agtctatcaa aaaagaccca agcaaggctg agaactatgc
    29281 tgaaatccac cgtcgtttac gacttggaaa tctcatggtc ttgacagctc aaggaactcc
    29341 atttatccac tccggtcagg aatatggacg tactaaacaa ttccgtgacc cagcctacaa
    29401 gactccagta gcagaggata aggttccaaa caaatctcac ttgttgcgtg ataaggacgg
    29461 caacccattt gactatcctt acttcatcca tgactcttac gattctagtg atgcagtcaa
    29521 caagtttgac tggactaagg ctacagatgg taaagcttat cctgaaaatg tcaagagccg
    29581 tgactatatg aaaggtttga ttgcccttcg tcaatctaca gatgccttcc gacttaagag
    29641 tcttcaagat atcaaagacc gtgtccacct catcactgtc ccaggccaaa atggtgtgga
    29701 aaaagaggat gtagtgattg gctatcaaat cactgctcca aacggcgata tctacgcagt
    29761 ctttgtcaat gcggatgaaa aagctcgcga atttaatttg ggaactgcct ttgcacatct
    29821 aagaaatgcg gaagttttgg cagatgaaaa ccaagcagga tcagtcggaa ttgccaaccc
    29881 gaaaggactt gaatggactg aaaaaggctt gaaattgaat gcccttacag ctactgttct
    29941 tcgagtctct caaaatggaa ctagccatga gtcaactgca gaagagaaac cagactcaac
    30001 cccttccaag cctgaacatc aaaatgaagc ttctcaccct gaacatcaag atccagctcc
    30061 agaagctaga cctgattcta ctaaaccaga taccaaagta gctgatgcgg aaaataaacc
    30121 tagccaagct acagctgatt cacaagctga acaaccagca caagaagcac aagcatcatc
    30181 tgtaaaagaa gcggttcgaa acgaatcggt agaaaactct agcaagaaaa atatacctgc
    30241 aaccccagat agacaagctg aacttccaaa tacaggaatt aaaaacgaaa acaaactcct
    30301 atttgcagga atcagcctcc ttgcgctcct tggtctcggt ttcttactaa aaaataaaaa
    30361 agagaactaa actagccctc ctatagaaaa atcccccaag cattatagct cgggggatta
    30421 attttcgtac aatatttgtt gtcctaataa acttgattag gattttttat taagcctctt
    30481 tcatagcaaa ataagctcgt actttgggtg caacttgtgt tccgaagagt tcaatagctc
    30541 tcagaacctg gtcatgaggc atagaaccaa gcggtagatg aagcatgaag cggtccaatc
    30601 ctaaatcctc tatcatgcga atcaattttt cggccacctg atctggattg ccaacaaaca
    30661 tggcgccatt tgaccctacc tgctccaaat attgctcata acgcaattcc tgccagtgcg
    30721 gacggtcttt ggaaatagca tccaccactt gcttagtcgg atggaaataa tctttcaccg
    30781 cctgctcacc atcttccgca atccaccccc aagaatgggc tcccactttc aagtctttgt
    30841 cagcatggac cgcttcgctt ccaatctcac gataagcctg aatcaacttt ttaaaataac
    30901 gtggattacc accaataata gcatatacaa tcggtagacc agcctgagca atcttcactg
    30961 ttgattcgac atgaccacct gtagctatcc acaagggcaa tttgtcctga actggacgag
    31021 gataaacttc tttaccagca atcgtttgag tcaatcgacc ttgccagtct aacttggtct
    31081 tttcattgac taactgaagc aagtctaatt tctcatcaaa aagagagtcg tagtctttca
    31141 agtcataacc aaacagaggg aaagattccg tgaaagagcc ccttccagcc ataatctccg
    31201 ctcgtccatt tgacaaagca tcgatagtgg catactgttg gaacaaacga atcggatcca
    31261 tgcttgacag aatgctgact gcactggtca aacggatttt cttggtattg actgccccag
    31321 cggccaggac aatctctggg gctgatactg caaaatccgc ccgatggtgc tcgccaatcc
    31381 catatacgtc caaaccaacc ttgtcagcca gctcaatctc tgccaccaac tggcgaatgc
    31441 gttcagcatg actgtaagtt tgtccagtcc cttcaagctc cgttatttcc ccaaatgttg
    31501 aaattcccaa ttctaccatt gtgattctcc ttgtctatct ctgtccttca atttgaaaaa
    31561 ttattctaac actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca
    31621 aaacagtgtt ttgaggttgt ggatagaact gacgaaatca gtaaccatac ctacggcaag
    31681 gcgacgttga cgtggtttga agagattttc taagagtata acacgaatct tgagtacaag
    31741 caaccaattt gctcacaaga aaaagcctag ataactagac ttttttagct tattctaccg
    31801 ttactgactt ggcaaggtta cgtggtttgt ccacatcgag gccacggtgg agggttgcaa
    31861 agtaagcgac taattgcgtt ggtacgacca ttgaaattgg tgagaggtat ggatgtacgg
    31921 tcgtaaggac gatatcgtcg gtatctttgg ctacattctc ttctgcgata gtgaggactt
    31981 tggcaccacg ggctgcgacc tcttggatat ttccacgagt atggttggca agaactggat
    32041 ctgacaagag agccaaaaca ggcgttcctt cttcaatcaa ggcaatggtt ccgtgcttga
    32101 gttctcctgc cgcaaaacct tcacactgga tataagaaat ctctttgagt ttgagacttg
    32161 cttccatggc tacgtaataa tcttgaccac gtccgatgta aaaggcgtta cgagttgttt
    32221 caagaagttc acgaaccttg gcttcaatgg tttctttctc tgaaagagtt gattcaatag
    32281 actgagctac gattgacaat tcatgaacca ggtcaaaggc ttgcgcttta gcattaccat
    32341 ttgcttctcc gactgctttt gcaaggaagg caagggctgc gatttgcgct gtataggctt
    32401 tagttgatgc cacggcaatt tcaggacctg cgtgaaggag catggtatag ttggcttcac
    32461 gtgagagggt tgaacctgga acatttgtca ctgttaagct tggaattccc atttcattag
    32521 ccttgaccaa aacttgacga ctatccgctg tttcaccaga ttggctgata aagatgaaga
    32581 gtggtttctt gctgagaagt ggcataccgt agccccactc agatgagatt ccaagttcaa
    32641 ctggtgtatc tgtcaattct tccaacatct tcttagaagc aaatcctgca tggtaagatg
    32701 ttccagctgc aaggatgtag atgcggtctg cgtcttgaac agccttaatg atatctgggt
    32761 ctacgacaac ttgaccagcc tcatctgtgt aggcttggat gagtttccgc ataacagttg
    32821 gttgctcgtc aatttccttg agcatgtagt aagggtaagt tcccttaccg atatctgaca
    32881 agtcaagttc agcagtgtag ctagcacgct cacgacgatt tccatcatag tcttgaactt
    32941 ccacgctatc agccttgacg attaccaact cttggtcatg aatttccatg tattggttgg
    33001 tttcacgaat catagccata gcatctgagc agaccatatt gtagccttcc ccaagaccaa
    33061 tcaaaagtgg agatttgttt ttcgctacat agatgacatc tggattttca gagtcaatca
    33121 aggcaaaggc atatgaacca cggataatat gaagagcttt tttaaaggct tcaagaactg
    33181 agagaccgtc ttcttccgca aattttccaa tcaaatgtac ggcgatttcc gtatctgttt
    33241 gccctttgaa gtggtgccca gcaaggtatt cttctttaat ttcaaggtag ttttcaatca
    33301 ccccattgtg aaccaagaca aaacgttctg tctcagagcg gtgtgggtga gcattgtctt
    33361 ccgttggttt cccatgagtt gcccaacgag tatgtccgat accagttgtt ccctcaacac
    33421 cagctgtctt ggcagacaat tctgcgatac gaccaacagc cttcaccaaa tggttatcag
    33481 caccatctag gacaaaaatt cccgcagaat catagccacg gtattcaagc ttttcaagcc
    33541 cttgaatcaa aatatcagtt gcatttgtgt ttccaacaac accaacaatt ccacacatag
    33601 tatatacgac acaggcaagc tgtgctttct ccttaaaatt ggtatagtct aattcatctt
    33661 ttatagaatc agcaaaaaca gtatatactt gtttctttca cttgtcaaga gtaaaaattg
    33721 gtatagtcta attcatcttt tatagaatca gcaaaaacag tatatacttg tttctttcac
    33781 ttgtcaagag taaaaattgg tatagttcaa attaagctcc tgtaagcaaa aaactctgac
    33841 cgattgggat aatcagtcag agtccttttt aaaatccatt attatcgctt aattttttga
    33901 accagtggcc tgatttcttc agacgacgtt cttgcgtttc caagtctaat tcgaccaaac
    33961 catagcgatt tttatagctg ttgagccatg accagcagtc aataaaggtc caaatcaagt
    34021 agcccttaca gttggcacca tcttcaatgg cacggtgaag ttcacgaaga tgacctttta
    34081 caaagtcaat acggtaatca tcttgaatca ttccatcttg acggaatttt tcttcccctt
    34141 caacacccat accattctca gtcaacatcc attcaatatt gccataattt tccttgatat
    34201 tttgggcgat gtcataaatc ccttgctcat aaatctccca accacggtga gaattgattt
    34261 tacgtccagg catcacataa ggctcgtaaa aatgttctgg taagagtgga ctctctggat
    34321 gcttagcaaa tcgaggagcc ataacacgca aaggttgata gtagttcaca ccaaggaagt
    34381 ccaccgtatt atcatgaatg agttccaact cttcctctgt agcatcaggt aaaagaccgt
    34441 gttcatgcaa gatttctacc aactcctgtg gataagtccc caagacagat ggatctaaga
    34501 aagattgggc ctgaaaaagg gccgcaatac gagctgcctt gacatcagca ggatgctggc
    34561 tacgtggata agccggtgtc aagttgagga caatcccaat cttggaatca ggcaaaagtt
    34621 catggcaagc cttaacagcc cggctgctgg ccaattgtgt atgataggct accttaacag
    34681 ctgcctctgc atccacctta tgtggataat gggcatcata aaaataacca aattctacag
    34741 gaacgatggg ctcgttaaag gtaatccatt gatccactaa atctccataa gtctcaaaac
    34801 aaaaacgagc atagtcttca taggctgaga ctgtcgcctt attttcccaa ccatcaccat
    34861 cctcttgaag ggcaaaaggt aaatcaaaat gatagagatt gactaacaga cgaattcctt
    34921 tagccttaat agcctcaaag accttacgat aaaaatccac accttgaggg ttgacttttc
    34981 cacagccttg tggaaaaatc cgtgaccact gaatagaagt ccgaaagact gtgtgaccag
    35041 tctctaacaa aagctcaata tcccgctccc aattttcata aaaagtcgat gtcttatctg
    35101 aaccaatccc attatagtaa cgatttggct ccacttggaa ccagtaatcc cagagattgt
    35161 ctcccttacc gtcaccagct acacgtcctt ctgtctgcgg tccagaagta gaggatcccc
    35221 agacaaaatc ctttggaaat cttagcataa catttacctc tttatctact catttctccc
    35281 attatacaga aaaaacaagg taaaaactag ttacattttt tccttgtttt tcttctgatt
    35341 atagttttta tttcttgctt aggatttcaa gcgtttcaag cacgttatct gcatgaacct
    35401 caatggtgtc accagttgcc ttgatcttaa cttctacaat gccatcggcc gcttttttac
    35461 caacagtgat acggattgga agaccaatca agtcactatc gctaaattta acaccgacac
    35521 gttcgttacg gtcatctgtc aagacttcat aaccagctcc catcaagctt gcttcaagtt
    35581 tttctgtcaa ggcttgcgct tcttcatcct tgacattgac agtaatcaaa tgcacatcaa
    35641 atggtgccaa ttctttaggg aaattgattc cccaagcgta acggtattca ccttttggcg
    35701 ttttgttaac aaagaggcga gcgtgttgct ccatcactgc tgaaagaaga cggctgacac
    35761 cgataccgta acatcccatg atgattggca cagcacgacc attttcatcc aagacatctg
    35821 ctcccatgct tgctgagtag cgagttccga gtttgaaaat atgaccgatc tcaataccac
    35881 gcgcaaagtt aaggacacct tgtccatctg gggaaatttc accctcacga acttcacgga
    35941 tatccacata ttctgcagta aaatcacggc ctgggttcac accagtcaag tggtagccat
    36001 cttcgttagc accgacaact gcattgcgaa catcttgcac cttacgatct acaataattt
    36061 taatattctc tggcaaacca actggtccaa gtgaaccaaa tcctgcttga acaacattcg
    36121 ccacttcttc ttcgctagca acgtcaaaga aatctgctcc taagtggttt ttcaacttga
    36181 cttcgttgag ttggtcattt ccaactagaa gggctgcaac aagctcacca tctgcaatgt
    36241 agaagagggt tttaatcgtt tgttcttctg gaacattgag gaaagctgca acttcatcaa
    36301 ttgatttaac atctggcgtt gcaacacgag taacttcttc ttcagcgaca acacggttgc
    36361 ttggtttgta ctcgtttgtt gccatttcta agttagctgc atagctagac tcacttgagt
    36421 aagcaatggt atcttcacca gagactatcc atttgagcaa ttctgccttg atttcttctt
    36481 gcacttctgc aggaatttcg tcaaatgagg caactgactt gtccaagaca acccagcggt
    36541 caaggtctgt acgagcagat gtaatggcca taaattcttg gctatcctta ccacccatgg
    36601 ctccaccgtc accaataata gccttgaagt ctaaaccact acgagtgaaa atacgctcat
    36661 aggctgcttt gtactcatca taaacactat ccaaactatc atagttagcg tggaaactat
    36721 aagcatcctt catgataaac tcacgtgtac gaagaagtcc attacgtggg cgtttttcat
    36781 cacgatactt gggctgaatt tgataaaggt tgagtggcaa ttgcttgtaa gatttaacag
    36841 aatcacggac aatagctgta aaggtttctt cgtgagttgg acctaagata aagtctgatt
    36901 tttcacggtt ttttagtttg taaaggtctt caccataggt ttcgtaacga cctgattcac
    36961 gccacaattc tgcactaaga agggctggag ccaacatctc aacagcacca atcttttcga
    37021 attcttggcg catgatgttt ttagcttttt caatcacacg attggcaagt ggtagataag
    37081 aataaacacc tgctgaaact tggcgaacat aaccagcacg caacataaga gcatggctga
    37141 taacttgagc atcgcttggc atttcgcgaa gcgttgggat aggcatttta ctttgtttca
    37201 taatattcct cgattatcta aaaaagagtc gcataatgtc attccaagtc acagcaatca
    37261 tcaagacaac catgatgacc actccggcca aggtgacata ggtttcaatt tcttgtttca
    37321 atggtttgcg gcggatggct tctaggatat tgagcacaat cttaccacca tccaaggctg
    37381 gaatcggaat aagattaaaa atcccaatat tgatggaaat cattgccaag aagtacaaga
    37441 tattttcaat tccattttta gcagcatcac tacttgcctt aaagatagca acaggtccac
    37501 ccaacttgtt caaatccggt tggaaaatca gatttttcag agctgagaga attcggagag
    37561 ctgagtcagc agcagttgta aaaccaccta caaacatgga tagaaaatct gacttaaccc
    37621 ccggttgaac acctagaagg taacgacctt gactatcttc gggtgtaaca gtgacttgtt
    37681 tgtcactccc cttttcagaa atagtcacat ccaaagtcgg tgccgtctta tctttggttt
    37741 ctgtttccac agcttggatc aagctttccc agttgctaac ctcatgtgag ccaatcttgg
    37801 taatttgtgc cgtttctggt actcctacct tggccaaggc accttggggc atgatatgga
    37861 actgattggt atcaacatct ctgacaccac cctgcataaa gattaaaacc caaaaaacaa
    37921 cgacacctaa gataaaattg ttcataggac ctgcaaaatt ggtaatcagt ttgccccaga
    37981 tagtcgcatt ttgatattga acatctaaag gtgcaatccg aacctcagta ccatctgctt
    38041 ccacaaccgt tgcatcgtga tccactgcaa atgttttttc ttcttccaga accaatcctt
    38101 tgataaagag cttgtcttca aaatcaaact gggtcacctg catagggagg gctgtttgat
    38161 ccaatttttt acctgagaga ttgatgcgtt taaccttacc atcatcagca agtgtcaaac
    38221 taacaggcgt tcctgtcttg atttcagttg tatcatcacc ccaaccggcc atgcggacat
    38281 agccacccag aggcaagatt cgaatggtat aggccgttcc atccttgcca atgtgagcaa
    38341 aaattttagg tcccataccg atggcaaatt cacgtactaa aatccctgat ttcttggcaa
    38401 agtagaagtg cccgaactcg tgcaccacta caataatccc gaaaaccaga ataaaggtta
    38461 aaattccgag catagcgttt cctccgtctt ttgattaaaa gagtccaaat aagtgcatga
    38521 ttggaaatac aagcaacata ctatcgaaac gatccaaaac accaccatgt ccagggataa
    38581 atttcccaga atccttaaca ccaaaatgac gtttgatcga actttctagt aaatcaccaa
    38641 attgtccagc aatgctaaag aaaatagcaa agactgacat cttgtaaatt ccatatggaa
    38701 gagcaactgt actgtcaact atcataaaga taatggttac taaaattgct cctaaaatac
    38761 cacccaaggc accctcaagg gttttattag gcgataccct tggtgctaac tttcgtttcc
    38821 catagttcat cccaacaaga taggcaccac tgtctgtcgc ccagacgata cacaaggcta
    38881 agagagcctt gtccaaacct gcaacacgag catctagtaa agcattaaat ccaaagccca
    38941 cgtagaagct catagcaaga gggaaaaccg catcctcaat cgtataagac ttgctaaaaa
    39001 cggtcgttcc taacatgatt gaaatcaaaa cactataggc aaccacattc ccatcaactg
    39061 gcaaaaaagt caggtaattc tccaagggaa tggtcaatgc aaaggttgca aagagggtca
    39121 agaggccctc catcgtcatg gtctctagac ctctcatctt caaaagttca tgcatggcta
    39181 gcatggctat gattccgatt gctatctgaa gcaagaggcc cccaatcatt aaaattggta
    39241 ggaaaatagc cagggcaatc cctgcaaaca aggttctttt ctgtaaatcc tgggtcatat
    39301 ttcctcctaa actcctccaa atcggcgatg acgacgatta taggcaagaa tagcttcctg
    39361 caaggccgct tcgtcaaaat caggccataa ggtgtccgta aaataaagct cactataggc
    39421 tccctgccat ggaagaaaat tgctcaaacg taattctcca ctagtacgga taatcaagtc
    39481 tgggtctcgt aagtccttag gcaaatgctg agtaaagaga tagttaccaa tcaattcctc
    39541 tgtgatgtca cctgggttga ttttggcatc taaaacatcc tgggaaatca acttaagcgc
    39601 ctgtgtaatc tcagcacgtc caccatagtt aagagcaaaa ttaagaatca atcctgtgtt
    39661 gttcttagtc aattcctcag ccttggttaa agcttcaaag gtttgcttag gcaggcggtc
    39721 tgtctcccca atcatttgaa tcttaacatt attcgcatgt agttccggga cataattatc
    39781 ataaaactct actggcaagt tcatgataaa cttgacttcc tgatctggac gggtccagtt
    39841 ttccgtagaa aaagcataga ccgtaataac cttgacgccc agtttgttgg ctgccttggt
    39901 cacggtttgc aatgcttcca tgcccgcctt atgtccaaaa actcgcggtt gcatacgttt
    39961 tttagcccaa cggccattgc catccatgat gatgccgata tgagcaggaa cctgtgtcgg
    40021 aacctctact tccacagcct tatctttctt aaaaaatcca aacatgatct tattcctatt
    40081 caaaaatcta tcgtttcatt ataccatatt tccccatttt cttctatcac taagctattt
    40141 attctcaggc accatgccca tttttcaaaa aaataagccg cctgattggg cgactttatt
    40201 tttataggga gattattatg aaaaagtttt aggagtttaa gttaaggtct tcttaactta
    40261 tgaacttagt gtacactccc tagcttaaag tttccttaag tatttttaaa aatcaaattt
    40321 ttccatttct cctgccaatt tttcttggat aaacgtgttt gatagagttc cattcggtct
    40381 tcattttcta agaaatgagg agttggacga acttgaaaat tcaaaatatc ctccaaacca
    40441 taaggtgcat agagttcaaa atctgattct tcattcaagc gcagtccaac tgccgtacac
    40501 cgttctggat acttactcat agcatcacga gaactggtat aggaagcagt gtgaggactg
    40561 tgctgatgca tatagacctg atttttcaat tcccactggt actgaggaaa atcctctctc
    40621 agctttttct ccagtaataa ggtttcctca taagaaaaat ctggatcaaa gaaaatcaca
    40681 tctatatctg tttcatgatc aaaaggggat ttgtctgaca aaagattcca gatgaaattt
    40741 ctgacagaac ctgctgccaa ctacgagtct ttcaaaccaa ggtctcggat gatcgtcaga
    40801 atggccatca tatctggatt ttctctaaaa gcctctaaga tttcttgctt atttttcact
    40861 gtattcataa cctaagtgct catatgcctt agcagtcgcc acccgtccag accgtgtccg
    40921 catgataaaa cctttttgaa tcaagtaagg ctcatacatg tcttcaactg tctcacgctc
    40981 ttcggcgata ttgacagaaa gagttcctag accaacaggt cctccactgt acatctcaat
    41041 catggtacga aggatttttt gatccacata gtccaaacct tcatggtcaa catccagcat
    41101 agtcaaagcc ttatcggtaa taatatcatc gattacccca ttccccatta tctgggcaaa
    41161 atcgcgcacg cgcttgagga gacgattggc aatacgaggg gttccacgac tacgtagggc
    41221 caactcagat gctgcctcat gagtgatttc catctcaaaa atatctgccg tccgctcgac
    41281 aatttctgtc aagtcagcat gggcataata ctccatatga cctgtaatcc caaaacgtgc
    41341 ccgtagtgga tttgagagca taccagcccg agtcgtcgca ccaatcaagg taaaaggagg
    41401 caactccaaa tgaacactgc gactgccttc accagcccca atcataatat cgatgtagaa
    41461 gtcctccatg gcactataaa gcacttcttc cactgacatg ggtaagcgat gaatctcgtc
    41521 aataaagagg acatctccag gctctaactc attcaaaatc gctaccaaat cacccgcttt
    41581 ttcgataaca ggaccagacg tttgcttgag attgactccc agttcattgg caatgacaaa
    41641 agccatggtt gttttcccaa gccctggagg gccaaataag agcacatgat ccagcgcttc
    41701 atcccgcatt ttagcggctt cgataaagat ctgaagctga tccttaacct tatcctgacc
    41761 aatatattca cgtaaatact gaggacggag cgtgcgttct actaactcct catcacccat
    41821 catctcatta tctaaaattc tactcatggc tctattatat caaaaaaaca agccacaaac
    41881 aaaaaagcca cctgattggg tgactcctaa gtttagcact tatgtggtat aatattatac
    41941 ggcacttcta caccgcctac gaaaggaggt gagatagccc atgatggaat tagtactcaa
    42001 aactatcatc ggaccaattg tggtcggtgt cgttcttcgt atagtcgata aatggctaaa
    42061 caaggacaaa tagtgtcaaa aaagacctca agcttatttg gtcgtgagct tggggtcttt
    42121 tctagcctat gatatagaac tagtactcaa ttccttttta ttatcccata gttcacgaat
    42181 tttgtcaaag gtttacattt tcttcaaccg ctgtacgaca agacggttaa gattaagaga
    42241 acgttaggga ttctatcaat ttcatagaaa ttttgatttc gtaaacgaag agacaatctt
    42301 acatgtcact tctcatttaa tacgccacta ctagacaagc aaaatcatta ttacagtagt
    42361 tccagtcctt caattaacag tcacttacaa tcaaattgag tttgaactag ctgaagcgac
    42421 cacagaccta tttcttagtc atattcgcta aaaaagtccc cgccaattcc ccgaccaaaa
    42481 tccgaaaaat accgaaaaat atcgaaaaat tatttttaga atagtcccca aaagcctgaa
    42541 atagagctaa aaaactccac ctgattgggt ggagttaagg gagattatta tgaaaaagaa
    42601 aagtttagga ttttattaaa ta
//
LOCUS       DBJKQU010000011        39708 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.011, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000011 DBJKQU010000000
VERSION     DBJKQU010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39708
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.011"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..205
                     /locus_tag="ACSUUC_000695"
     CDS             <1..205
                     /locus_tag="ACSUUC_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000967644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053963.1"
                     /translation="DFETVKTRVISDFESYLKLLNGKFEESLKKVIKSFTFSKLIGEK
                     LCNGEDLKNLSKEIRHQIQDRNS"
     gene            468..1745
                     /locus_tag="ACSUUC_000696"
     CDS             468..1745
                     /locus_tag="ACSUUC_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HHQ8053964.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1821..3305
                     /gene="thrC"
                     /locus_tag="ACSUUC_000697"
     CDS             1821..3305
                     /gene="thrC"
                     /locus_tag="ACSUUC_000697"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HHQ8053965.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDTSYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3366..4646
                     /locus_tag="ACSUUC_000698"
     CDS             3366..4646
                     /locus_tag="ACSUUC_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHQ8053966.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4650..5270
                     /locus_tag="ACSUUC_000699"
     CDS             4650..5270
                     /locus_tag="ACSUUC_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHQ8053967.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5436..6548
                     /locus_tag="ACSUUC_000700"
     CDS             5436..6548
                     /locus_tag="ACSUUC_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HHQ8053968.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            6871..7296
                     /locus_tag="ACSUUC_000701"
     CDS             6871..7296
                     /locus_tag="ACSUUC_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHQ8053969.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAIQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7307..7708
                     /locus_tag="ACSUUC_000702"
     CDS             7307..7708
                     /locus_tag="ACSUUC_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HHQ8053970.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKIHLKVDSNLANPF"
     gene            7783..8427
                     /gene="pcp"
                     /locus_tag="ACSUUC_000703"
     CDS             7783..8427
                     /gene="pcp"
                     /locus_tag="ACSUUC_000703"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HHQ8053971.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(8455..9312)
                     /locus_tag="ACSUUC_000704"
     CDS             complement(8455..9312)
                     /locus_tag="ACSUUC_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HHQ8053972.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFILDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9442..10584
                     /gene="tgt"
                     /locus_tag="ACSUUC_000705"
     CDS             9442..10584
                     /gene="tgt"
                     /locus_tag="ACSUUC_000705"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HHQ8053973.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10685..12502
                     /locus_tag="ACSUUC_000706"
     CDS             10685..12502
                     /locus_tag="ACSUUC_000706"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HHQ8053974.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHIILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12655..13806
                     /gene="nagA"
                     /locus_tag="ACSUUC_000707"
     CDS             12655..13806
                     /gene="nagA"
                     /locus_tag="ACSUUC_000707"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HHQ8053975.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            13969..15027
                     /locus_tag="ACSUUC_000708"
     CDS             13969..15027
                     /locus_tag="ACSUUC_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HHQ8053976.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15178..15543
                     /locus_tag="ACSUUC_000709"
     CDS             15178..15543
                     /locus_tag="ACSUUC_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HHQ8053977.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15619..16560
                     /gene="comGA"
                     /locus_tag="ACSUUC_000710"
     CDS             15619..16560
                     /gene="comGA"
                     /locus_tag="ACSUUC_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HHQ8053978.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16508..17524
                     /gene="comGB"
                     /locus_tag="ACSUUC_000711"
     CDS             16508..17524
                     /gene="comGB"
                     /locus_tag="ACSUUC_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HHQ8053979.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17526..17852
                     /gene="comGC"
                     /locus_tag="ACSUUC_000712"
     CDS             17526..17852
                     /gene="comGC"
                     /locus_tag="ACSUUC_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HHQ8053980.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKEDGRITEEQAKAYKEYNDKNVGA
                     NRKVND"
     gene            17845..18249
                     /gene="comGD"
                     /locus_tag="ACSUUC_000713"
     CDS             17845..18249
                     /gene="comGD"
                     /locus_tag="ACSUUC_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HHQ8053981.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18212..18514
                     /gene="comGE"
                     /locus_tag="ACSUUC_000714"
     CDS             18212..18514
                     /gene="comGE"
                     /locus_tag="ACSUUC_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HHQ8053982.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18477..18938
                     /gene="comGF"
                     /locus_tag="ACSUUC_000715"
     CDS             18477..18938
                     /gene="comGF"
                     /locus_tag="ACSUUC_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HHQ8053983.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            18916..19329
                     /gene="comGG"
                     /locus_tag="ACSUUC_000716"
     CDS             18916..19329
                     /gene="comGG"
                     /locus_tag="ACSUUC_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HHQ8053984.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            19466..20060
                     /locus_tag="ACSUUC_000717"
                     /pseudo
     CDS             19466..20060
                     /locus_tag="ACSUUC_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            20121..21074
                     /locus_tag="ACSUUC_000718"
     CDS             20121..21074
                     /locus_tag="ACSUUC_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHQ8053985.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYTHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21125..22315
                     /locus_tag="ACSUUC_000719"
     CDS             21125..22315
                     /locus_tag="ACSUUC_000719"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HHQ8053986.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFSCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22316..22447
                     /locus_tag="ACSUUC_000720"
     CDS             22316..22447
                     /locus_tag="ACSUUC_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8053987.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            22464..22835
                     /gene="rnpA"
                     /locus_tag="ACSUUC_000721"
     CDS             22464..22835
                     /gene="rnpA"
                     /locus_tag="ACSUUC_000721"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HHQ8053988.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            22810..23634
                     /locus_tag="ACSUUC_000722"
     CDS             22810..23634
                     /locus_tag="ACSUUC_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HHQ8053989.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            23653..24639
                     /gene="jag"
                     /locus_tag="ACSUUC_000723"
     CDS             23653..24639
                     /gene="jag"
                     /locus_tag="ACSUUC_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HHQ8053990.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            24690..25313
                     /locus_tag="ACSUUC_000724"
     CDS             24690..25313
                     /locus_tag="ACSUUC_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HHQ8053991.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25444..26901
                     /locus_tag="ACSUUC_000725"
     CDS             25444..26901
                     /locus_tag="ACSUUC_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HHQ8053992.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            26924..27205
                     /locus_tag="ACSUUC_000726"
     CDS             26924..27205
                     /locus_tag="ACSUUC_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHQ8053993.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27282..27767
                     /locus_tag="ACSUUC_000727"
     CDS             27282..27767
                     /locus_tag="ACSUUC_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHQ8053994.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            27784..28449
                     /locus_tag="ACSUUC_000728"
     CDS             27784..28449
                     /locus_tag="ACSUUC_000728"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HHQ8053995.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            28453..29316
                     /locus_tag="ACSUUC_000729"
     CDS             28453..29316
                     /locus_tag="ACSUUC_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HHQ8053996.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29318..30022
                     /locus_tag="ACSUUC_000730"
     CDS             29318..30022
                     /locus_tag="ACSUUC_000730"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HHQ8053997.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKTWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30201..31874
                     /locus_tag="ACSUUC_000731"
     CDS             30201..31874
                     /locus_tag="ACSUUC_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHQ8053998.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEQEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNESKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            31986..33077
                     /gene="ulaG"
                     /locus_tag="ACSUUC_000732"
     CDS             31986..33077
                     /gene="ulaG"
                     /locus_tag="ACSUUC_000732"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HHQ8053999.1"
                     /translation="MPNVKEITRELWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RINVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLTVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33191..35167
                     /gene="tkt"
                     /locus_tag="ACSUUC_000733"
     CDS             33191..35167
                     /gene="tkt"
                     /locus_tag="ACSUUC_000733"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HHQ8054000.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAIEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            35284..35583
                     /gene="yajC"
                     /locus_tag="ACSUUC_000734"
     CDS             35284..35583
                     /gene="yajC"
                     /locus_tag="ACSUUC_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HHQ8054001.1"
                     /translation="MNPNYTFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35630..36058
                     /locus_tag="ACSUUC_000735"
     CDS             35630..36058
                     /locus_tag="ACSUUC_000735"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HHQ8054002.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36060..36470
                     /locus_tag="ACSUUC_000736"
     CDS             36060..36470
                     /locus_tag="ACSUUC_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HHQ8054003.1"
                     /translation="MENPTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            36771..39422
                     /gene="adhE"
                     /locus_tag="ACSUUC_000737"
                     /gene_synonym="adhC"
     CDS             36771..39422
                     /gene="adhE"
                     /locus_tag="ACSUUC_000737"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HHQ8054004.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12156 a         7048 c         8875 g        11629 t
ORIGIN      
        1 agactttgag accgtcaaaa cgagagtgat atcagatttt gaaagctatt tgaagcttct
       61 aaatggcaag tttgaagaaa gtctcaagaa agttattaag tcttttacct ttagtaaact
      121 cattggagaa aaactatgta atggtgaaga cctaaaaaat ttaagtaaag aaataaggca
      181 tcaaatccaa gataggaatt cctaaaaaat tactaaaaac taaaataatt attgttttta
      241 tagtataact aatttcttaa aacattgaat taatctgaat tatgacgtaa gtctgctaat
      301 ttcactgctc tcaaaatcca gtgtccgcaa ggacgtgccg gttcgacccc ggccgccggt
      361 atagtatagt gttaggaacg ttgttattct tcgttctttt tttatattat ttttggtata
      421 attatagtta ttcaaatttt atttagatta agaaagtgta gggtagtatg tcttgttcta
      481 tcgatttatt aaaacatcgg tatttgaaaa atattaaaga aaatcctgaa ttgtttgtcg
      541 gaattgagtt ggagtatcct gttgcaagtt tagaagggga tgctacagat gttgaagtta
      601 taaaggatct atttcattat ttagtttcta ctttggatct caccgtagca aaggtagatg
      661 attttggcaa tctgatccag ttagtagatc cgataagtca ggatgctatt ttatttgaag
      721 tttcctatac aacgattgag tttgcatttg gtaaggctga aacgattcaa gaggtcgaaa
      781 atcgtttcaa taattatatg aatgtaattc agagaaagtt agctgaatca aatcatgcta
      841 ttgttggctg tggtatccat cccaactggg ataaaaatga gaattgtcca gtggcttatc
      901 cacgctatca gatgttgatg gattatttga atttgagtag aaatattatt aaatcagatt
      961 tacatcattt ccctgaatat ggtactttta tctgtgggag ccaggttcag ctggatattt
     1021 caaaaaccaa ctacttacgg gtgattaatg cttttactca aattgaagcg gctaaggctt
     1081 atttatttgc aaactctgaa ttttcgggtg cggattggga tacgaaaatt tcaagggata
     1141 ttttctggga agaatctatg catggtatct atccagagaa tgttggggtc aatgctagac
     1201 tccttaatga tgaagctgat ttttttgact atctaaatca ttctgcgatt tttactgcgg
     1261 aacgtgatgg gcagacctat tatttttatc ctattcaggc tggggactat ttggctacgc
     1321 ctgaaatcca agcatttgct ctgaatgggg atgaggttat tatttccccc caagagaagg
     1381 attttgaaac tcatcgtagt taccagtacc aagacttaac gactcgagga acagttgagt
     1441 ttcgtagtgt gtgtacacag ccacttgata ggacttttgc ttctgcagct tttcacttgg
     1501 gattattggt taatttagac aagttagaag cttacttaga aacagcacct ttctttaaag
     1561 tatttggtta tgattacaag tctttaagga gacaattttc taagaaaaat cttacagatg
     1621 aggaagaaac tacgattatt gaattttcca aagacttact cctactagct gaggagggac
     1681 tagtggtgag aaataaggaa gaaatgacct atttacagcc tttgagagaa gaattgagcc
     1741 tataatttct cttataaagg gagaattttc tgaaaaatca tgatataatg gacgagacta
     1801 tagataaagg atagagagta atgacattag tttatcaatc aacgcgtgat gccaacaata
     1861 cagtaactgc tagccaagca attttgcaag gtttggcgac ggacggcggt ttgtttacac
     1921 cggttactta tccaaaggta gatttggact ttgacaaatt gaaagatact tcttaccagg
     1981 aagttgctaa gctagttttg tcagcatttt tagatgactt tacagctgag gagttggact
     2041 actgtatcaa caatgcctac gatagcaaat ttgatactcc agctattgca ccattagtga
     2101 aattagatgg gcaatacaat ttggaacttt tccatggttc aacgattgcc tttaaggata
     2161 tggccttgtc tattttgcca tactttatga cgactgctgc taagaaacat ggtttggaga
     2221 acaagattgt tatcttgaca gcgacatctg gtgacacggg gaaagctgct atggcggggt
     2281 ttgcggatgt gcctggtact gagattatcg tcttttatcc aaaggatggt gtcagcaaga
     2341 ttcaagagtt acaaatgacc actcaaactg gcgacaatac tcatgttatt gctattgatg
     2401 gtaactttga cgatgcgcaa acaaatgtga agcacatgtt taacgacgtg gctcttcgtg
     2461 aaaaattgac taccaacaag ttgcaatttt catcagctaa ctctatgaac attggtcgtc
     2521 tggtgccaca aattgtttat tatgtttatg cttacgctca attggttaag actggtgaaa
     2581 ttgtagctgg tgaaaaggtt aacttcacag taccaacagg aaactttgga aatatcttgg
     2641 ctgcctttta tgccaaacaa attggtttgc cagttggtaa attaatctgt gcttcaaatg
     2701 acaacaatgt tttgacagac ttctttaaaa cacgtgtcta tgacaaaaaa cgtgagttta
     2761 aggtaacaac cagcccatct atggatatct tggtatcttc aaacttggag cgcttgattt
     2821 tccatctttt gggaaataat gctgaaaaga caactgaact tatgaatgcc ttgaacacgc
     2881 aaggacaata taagttgaca gactttgatg cagagatttt ggacctcttt gcagctgaat
     2941 atgcgactga ggaagaaacg gcagcagaga tcaagcgtgt ttgtgagtta gattcttata
     3001 tcgaggaccc tcatacagct gttgcttcag cagtttataa aaaataccaa tcggccactg
     3061 gagatgtaac taagacagtg attgcttcaa cagctagtcc atacaagttc ccagtagttg
     3121 cagtagaagc tgtaactgga aaagcaggtt taacagactt tgaagccttg gctcaattac
     3181 atgaaatctc aggcgttgca gtgccaccag cagttgatgg gcttgaaata gctccaattc
     3241 gtcacaagac aacagtggca gctgctgaca tgcaagcagc ggttgaggct tatttaggac
     3301 tttaagacag agggagcaaa ctcggttggg aaaccaactg agtttctttt catcaggagg
     3361 agagattgtt taagaaaaat aaagacattc ttaatattgc attgccagct atgggtgaaa
     3421 actttttgca gatgctaatg ggaatggtgg acagttattt ggttgctcat ttaggattga
     3481 tagctatttc aggggtttca gtagctggta atattatcac catttatcag gcgattttca
     3541 tcgctctggg agctgctatt tccagtgtta tttcaaaaag catagggcag aaagaccagt
     3601 cgaagttggc ctatcatgtg actgaggcgt tgaagattac cttactatta agtttccttt
     3661 taggattttt gtccatcttc gctgggaaag agatgatagg acttttgggg acggagaggg
     3721 atgtagctga gagtggtgga ctgtatctat ctttggtagg cggatcgatt gttctcttag
     3781 gtttaatgac tagtctagga gccttgattc gtgcaacgca taatccacgt ctgcctctct
     3841 atgttagttt tttatccaat gccttgaata ttcttttttc aagtctagct atttttgttc
     3901 tggatatggg gatagctggt gttgcttggg ggacaattgt gtctcgtttg gttggtcttg
     3961 tgattttgtg gtcacaatta aaactgcctt atgggaagcc aacttttggt ttagataagg
     4021 aactgttgac cttggcttta ccagcagctg gagagcgact tatgatgagg gctggagatg
     4081 tagtgatcat tgccttggtc gtttcttttg ggacggaggc agttgctggg aatgcaatcg
     4141 gagaagtctt gacccagttt aactatatgc ctgcctttgg cgtcgctacg gcaacggtca
     4201 tgctgttggc ccgagcagtt ggagaggatg attggaaaag agttgctagt ttgagtaaac
     4261 aaaccttttg gctttctctg ttcctcatgt tgcccctgtc ctttagtata tatgtcttgg
     4321 gtgtaccatt aactcatctc tatacgactg attctctagc ggtggaggct agtgttctag
     4381 tgacactgtt ttcactactt gggaccccta tgacgacagg aacagtcatc tatacggcag
     4441 tctggcaggg attaggaaat gcacgcctcc ctttttatgc gacaagtata ggaatgtggt
     4501 gtatccgcat tgggacagga tatctgatgg ggattgtgct tggttggggc ttgcctggta
     4561 tttgggcagg gtctctcttg gataatggtt ttcgctggtt atttctacgc tatcgttacc
     4621 agcgctatat gagcttgaaa ggataggaaa tgcaaaaaac agcttttatt tgggatttag
     4681 acgggacttt attggactct tacgaagcga ttttatcagg gattgaggag acttttgctc
     4741 agttttctat tccttatgat aaggagaagg tgagagagtt tatcttcaag tattcggtgc
     4801 aagatttgct tgtgcgggtg gcagaagata gaaatctgga tgttgaggtg ctaaatcagg
     4861 tgcgtgccca gagtctggct gagaagaatg ctcaggtagt tttgatgcca ggtgcgcgtg
     4921 aggtgctagc ttgggcagac gaatcaggaa ttcagcagtt tatatatact cataagggga
     4981 acaacgcttt taccattctc aaggacttgg gggtggaatc ctattttaca gagattttaa
     5041 ccagtcagag tggctttgtg cggaagccaa gtccagaagc ggctacctat ctgctagata
     5101 agtatcagtt gaattctgat aatacttatt atatagggga tcggactctg gatgtggaat
     5161 ttgcccagaa tagtgggatt caaagcatca actttttaga gtctacttat gaagggaatc
     5221 acaggattca agcgttagca gatatttccc gtatttttga gactaagtga taaaaagatt
     5281 gtgtcagttt tgtgacagag acctaacaaa ctatttcaag taacctagtt tgttacaagg
     5341 aatagacagt tctgttaaat aggcccgaga gggctttttt tctacatttt ttgtgttatg
     5401 atagacaggt actcatttga aaggaatttg aaagaatgaa gaaaagaatg ttattagcgt
     5461 caacagtagc cttgtcattt gccccagtat tggcaactca agcagaagaa gttctttgga
     5521 ctgcacgtag tgttgagcaa atccaaaacg atttgactaa aacggacaac aaaacaagtt
     5581 ataccgtaca gtatggtgat actttgagca ccattgcaga agccttgggt gtagatgtca
     5641 cagtgcttgc gaatctgaac aaaatcacta atatggactt gattttccca gaaactgttt
     5701 tgacaacgac tgtcaatgaa gcagaagaag taacagaagt tgaaatccaa acacctcaag
     5761 cagactctag tgaagaagtg acaactgcga cagcagattt gaccactaat caagtgaccg
     5821 ttgatgatca aactgttcag gttgcagacc tttctcaacc aattgcagaa gttacaaaga
     5881 cagtgattgc ttctgaagaa gtggcaccat ctacgggcac ttctgtccca gaggagcaaa
     5941 cgaccgaaac aactcgccca gttgaagaag caactcctca ggaaacgact ccagctgaga
     6001 agcaggaaac acaagcaagc cctcaagctg catcagcagt ggaagtaact acaacaagtt
     6061 cagaagcaaa agaagtagca tcatcaaatg gagctacagc agcagtttct acttatcaac
     6121 cagaagagac gaaagtaatt tcaacaactt acgaggctcc agctgcgccc gattatgctg
     6181 gacttgcagt agcaaaatct gaaaatgcag gtcttcaacc acaaacagct gcctttaaag
     6241 aagaaattgc taacttgttt ggcattacat cctttagtgg ttatcgtcca ggagacagtg
     6301 gagatcacgg aaaaggtttg gctatcgact ttatggtacc agaacgttca gaattagggg
     6361 ataagattgc ggaatatgct attcaaaata tggccagccg tggcattagt tacatcatct
     6421 ggaaacaacg tttctatgct ccattcgata gcaaatatgg gccagctaac acttggaacc
     6481 caatgccaga ccgtggtagt gtgacagaaa atcactatga tcacgttcac gtttcaatga
     6541 atggataaac ccgacttgat aacatcattt tgacgaatga gatctagctt tcgtgatgga
     6601 aagcgattct cgttcgtttt ttctttgtca tactcttcga aaatctcttc aaaccacgtc
     6661 agttttatct gaaacctcaa agctgtgctt tgagcaacct gcgactagct tcctagtttg
     6721 ctttttgatt ttcattgagt atcaatttga atggaaaatg gaaagttatc atcttgtaat
     6781 gagttaagca acattcttgc aatctatttt actttatatc acaattaatt agtcaactat
     6841 tgataaatca ataaaaagag aggggaagaa atgctagaga ttcaagattt actgtatcaa
     6901 ctccgcttgt ctgagcaagc gagtacgcaa ttgtttgaaa aaaggcttgg gattagtttg
     6961 acacggtatc agattttact gtttttgctg gagcattctc cttgtaacca aatggcgatt
     7021 caggagcgtt tgaaaattga tcaggctgct ttgacacggc atttcaagat tttggaaacg
     7081 gaaggtttgg tggagcgtca tcgtaatcct gaaaatcagc gggaagtgtt ggtagaggct
     7141 gcgaagtatg ccaaggagca gttagtggtg aatccccctc tgcaacatat caaggttaag
     7201 gaagagatgg aaagtatctt aacagagttt gagagaacag aactcagccg tttattaaat
     7261 aaattggttt tgggtattga aaatatagaa atttaaggag aaatagatgt caattattac
     7321 aattatttta acaacgatcg ttgctttgga gcatttttac attttttatt tggaaagtat
     7381 tgctacgcga tcagatgcga ctagtcgtgt atttaatatg gaaaaggaag aattggctca
     7441 tccgtcagta agttcattgt tcaaaaatca agggatttat aaggctctgc taggagtctt
     7501 tctctggtat ggcatttatt tctcacagaa tttagaaatt gtgactattt ttgtcttatt
     7561 tgtgattggt gctgcgactt acggctcttt aacagcggat aaaaaaatta ttttgaagca
     7621 aggtggatca gctattttgg ccttgattag tattttactc tttaaaatac acttgaaggt
     7681 cgattctaat ctcgctaatc ctttttaatc cagaataagg gaaatatgtt atacttgttt
     7741 ttaagaaaaa agtctcattg aattggtttt gaggagttag aaatgaaagt attagtgaca
     7801 ggttttgagc cctttggagg ggaaaagggc aatccaactt tggaggccat taaaggttta
     7861 ccagctgaaa tccatggtgc tgaggtccgt tggctagagg tgccgacagt ttttcacaaa
     7921 tctgctcaag tattggaaga agagatgaat cgttatcaac ctgactttgt cctttgtatt
     7981 gggcaagctg gtggaagaac tagtgtgaca cctgaacgag tggccattaa tcaagacgat
     8041 gcacgcattt ctgataacga agataatcaa ccgattgacc gtcccattcg cccagatggt
     8101 gcttcggcct actttagtag tttgccgatt aaagcgatgg ttcaagctat aaaaaaagag
     8161 ggcttaccgg cctctgtttc caatacggca gggacttttg tctgcagcca tttgatgtat
     8221 caggctctct atttggtaga aaagaaattt ccatatgtta aggcaggttt tatgcatatt
     8281 ccttatatga tggaacaggt ggtgaacaga ccgactactc caactatgag tttagtggat
     8341 attcggcgag ggatagaagc agcaatcggc gctatgatag aacatgggga tcaggaactc
     8401 aagttggtag gcggagaaac tcattgatag aaaaaagctt gaggggaaaa accttcaagc
     8461 ttttggacgt tttcgagcca atactgctcg gtaaaacata attttagtgc attggatata
     8521 aggtaggagt gaaaaactag caatgccaaa ggtaatccaa ttgaggaagt accaaggaag
     8581 aagctgtaaa tctaggataa agtgctggaa cttgtagccc ttcataaagg aacggctagt
     8641 ttttaggatt cgtcttggtg ggacctgtcc taggtctaga ctataacaga gaagaaattc
     8701 cacctgtgaa taggcataat actgtggaat atagaggata tttcctacaa tgatcaagat
     8761 gagacttgca agaaagtaga gtccaaagac catgaggaaa cgctcggttt caactgatga
     8821 gagatctaga tttggaaact caggatgtag ggtgacgaat tttttggcta aaaagctact
     8881 ataaaagagg agataaatcc caagtaaatt agggatactc cataaaaaga gatagaaacg
     8941 tttgagaagt agggtcaaaa aggtttgaga aaagcgctcc tcatcaaaga gagctaggct
     9001 gttttttaca gatggctccg ttttagaatc tttcatgagt gtcagtgttg catagacgga
     9061 actggtcaaa agaatagtcc cgataaagga gactagtaga ggaaagaggt aggcttgaag
     9121 tatttggcca agtatgctga aaaatggctg ttctaaaaca gtcccgtgga tccgagataa
     9181 gggattaaga aaactagata agatgaccag catactggga aggatataga ggagaaagag
     9241 acggggggtg tcagcctgaa aatgttttga ctcctgacga attgttttta aatcaatttt
     9301 tggatagttc attctcttat tataccatag ttcttataca tagttcgtga cagttcctac
     9361 tttttttgat aaaatcatac agtgtgtact tgggcacact gtatgaactg ggactgtctt
     9421 tcccagcttc ggaggtaaaa aatgtcagat tcaccaatca aatatcgttt gattaagaaa
     9481 gaaaaacaca caggagctcg tctaggagaa atcatcactc cccacggtac ctttccgaca
     9541 cctatgttta tgccagttgg gacacaagcc actgtcaaaa ctcagtcacc tgaagaattg
     9601 aaggagatgg gttcgggaat tatcctatca aacacttatc atctctggct tcgccctgga
     9661 gatgaactca ttgcacgcgc tggtggtctc cacaagttca tgaattggga ccagcctatc
     9721 ttgacagata gtggtggttt tcaggtttat tctttagcag atagccgtaa tatcacagaa
     9781 gaaggagtaa cctttaaaaa tcatctaaat ggttctaaga tgttcctatc cccagaaaaa
     9841 gccatctcta ttcagaataa tctgggttca gacatcatga tgtcctttga tgaatgtcct
     9901 cagttttatc aaccttatga ctacgttaag aaatcgatag agcgtaccag ccgttgggct
     9961 gagcgtggtt tgaaggctca ccgtcgtcca catgaccaag gtttgtttgg aattgtgcaa
    10021 ggtgcaggat ttgaagacct tcgccgccaa tcagctcatg atcttgtcag catggatttc
    10081 tcaggctact ctatcggtgg tttggcagtg ggagaaaccc atgaagagat gaatgcggtc
    10141 ttggacttta caactcaact gctgcctgaa aataaacctc gttatctgat gggtgtggga
    10201 gcgccagata gcttgatcga tggggtcatt cgtggggtgg atatgtttga ctgtgtctta
    10261 ccgactcgaa ttgctcgtaa cgggacttgt atgaccagtc aaggacgttt ggttgtgaaa
    10321 aatgcccagt ttgctgagga ctttacgcca ctggatcctg agtgtgattg ctacacatgt
    10381 aataactata cacgcgctta ccttcgtcac ctgctcaagg ctgatgaaac ctttgggatc
    10441 cgcttgacta gctaccacaa tctttacttc ttgcttaacc tgatgaagca agtgcgacaa
    10501 gccatcatgg atgacaatct cttggaattc cgtgagtatt ttgtggaaaa atatggctat
    10561 aataagtcag gacgtaattt ctaaaatgga attgatataa gctaaaaatc ctaagttttc
    10621 tcttaggatt tttcttcttt ttttgataga ataaagtgta caatgaaagg aagaataaac
    10681 tcgtatgcgc attaaatggt tttccttggt taggattaca ggtttacttt tggtactctt
    10741 gtatcacttc tttcagacga tctttcctgg aggatttttc ggggtagatg tctttttcac
    10801 attttcaggt ttcctgatta cagctctact cattgaagaa ttttctaaaa accatgagat
    10861 tgatttgata ggatttttta gaagacgctt ttatcggatt gtgccacctg tggttttgat
    10921 ggtcttggtg accatgcctt ttactttctt ggttcgccaa gactatgttg ctggaattgg
    10981 tggccagatt gcgagcgtct taggctttat gaccaacttc tatgaactcc taacaggtgg
    11041 gagttatgaa tctcagttca ttcctcattt gtttgttcat aattggagtt tggcagttga
    11101 ggttcactac tatattcttt ggggattggc agtttggttc ttatccaaac aagctaaatc
    11161 aaatggtcag ttgaagggga tggtctttct cttatctgct gttgccttct tgatcagttt
    11221 cttctccatg tttattggta gttttctagt gacctcttat tcctctgttt atttctccag
    11281 tttaactcat gtctatccat tctttttggg aagtatgtta gcaactattg taggcgttcg
    11341 tcagacgact tccctcgtca agcagttgga taaaatctgg gatttacgaa agactttggt
    11401 agtttttgga ggaggctttg gtttcctagt tcttttgact ttctttgtca aattcactta
    11461 tctttttgcc tatcttatcg gcttcttact tgccagtctt gcagctcttg ccatgattct
    11521 ggcggcgcgt gtcttacatg aaaagacaca tcatatacag gagccgaaga ttatcagctt
    11581 tttagcggat actagctatg cggtttatct tttccattgg cctttctata tcattttctc
    11641 acagttgaca tcaaatcttc ttgctgtatt actgactctg atttgttctt atggctttgc
    11701 cagtctgtca ttttatgtat tggaaccttg gattgcaggc aagaacacac ctattgtcca
    11761 aacccttcgt cccctgcctt atattcacgc aattcttgca gcaggtacag gaatcttgac
    11821 catcattgtc tgcacggtga ccttgttggc accacaagtg ggagcgtttg agacagactt
    11881 gactgtcaat ggcttgaagc aagctgcaac aaatattggc cagaccaagg tgatggcaga
    11941 acgggcagat gcaaacagtt tgggaattgc tgatggcact atgttaattg gtgactcagt
    12001 ggctttaagg gcaaatacag cactacagac agctcttcct ggagcacaga ttaacgcgca
    12061 ggtcagcgta acaaccaaga ccgcaaatga aatcatgcta aataatagcc agaataaatt
    12121 tttacctaag acggtggtca ttgcgactgg ggtaaataat cctgagaatt acaaggatga
    12181 ctgggacagt atcgtgaaaa atcttcctaa gggacaccat ataattttgg tgactcctta
    12241 tgagggagat aagacaaaag agacctatgc catcgttgag aaggctgctg cctatatgag
    12301 agaattggca gagaagacac cttacattac gatagcagat tggaatcaag ttgcgaaaga
    12361 gcatccagaa atttgggcag gaacagacca ggttcatttc gggagtgaga gtagcactat
    12421 cgaagcagga gcaaaattgt atgcagatac gattgccaca gctttgcaga cagctcaaga
    12481 caagccggtt aaatcaaaat aacttgtatt aaaaaagaga agagttggag aaatccagct
    12541 cttttaaaat atctccaaaa aataggtcta taccatttac aaataaaaaa gaaaggttta
    12601 taatgtaatt gacataataa attgtagaat caatctttta aggaggttaa cattatgcct
    12661 aactatatta aagcggatca gtttttctac ccacacggag ttcgtcgagg tggttacttg
    12721 gaacttgtgg acggcaagtt tgggaaacat gtagagcaga ttcctgaagg ggctgaggtg
    12781 attgactata caggttatag cattgcccca ggtcttgtgg atactcatat tcatggatat
    12841 gcaggtgtag atgtgatgga caacaacatt gaaggtacat tgcatactat gagtgaagga
    12901 cttcttagta ccggtgttac cagtttctta cccacaactt taacagccac ttatgagcaa
    12961 ttgcttgcag tcactgaaaa tcttggaaac cattataaag aagcaacagg tgctaagatt
    13021 cgtgggattt attatgaagg tccatatttc acagaaactt ttaagggggc acaaaatcca
    13081 acttatatga gagacccggg tgttgaggag tttcattctt ggcaaaaagc ggcaaatggc
    13141 ttgcttaata aaattgccct tgcaccagaa cgtgatgggg tggaagactt tgttcgtaca
    13201 gttacgggcg aaggtgtgac ggttgctctt ggacattcaa acgcgacttt tgatgaagcc
    13261 aaaaaagcag tcgatgctgg agcgagtgtt tgggtgcatg cctacaatgg aatgcgtggg
    13321 ttgactcacc gtgaattggg tatggttgga gccatgtacc aattgccaca tacctatgca
    13381 gagttgatct gtgatggtca ccacgtagat ccaaaggctt gcgaaattct tatcaaacaa
    13441 aaaggaacag aaaacatcgc tcttatcaca gactgtatga cagctggggg attggaagac
    13501 ggagattata tgttgggaga attcccagtt gtcgttgcaa atggaactgc acgcctcaaa
    13561 tcgacaggta acttggcagg ttctatcctc aaactcaaag atggtttgaa gaatgtggtc
    13621 gaatggggaa ttgcgaatcc gcatgaagca gtcatgatgg ccagcttcaa cccagctaaa
    13681 tccgttcaca tcgatgacgt ctgtggccaa atccgtgaag gctacgacgc tgacttcatc
    13741 gtattagata aagatttgga attggtagca acctacctag atggcgtaaa acgttatcaa
    13801 gcataagaga gaaagcagaa gttagagact aacttctgct tttttatgca gggtacttta
    13861 ctggtaaata aaaagttaaa aaaatcacaa aaaaagcttg aagaaacaaa gaaaaaggct
    13921 tataattgaa ctataaatat tacaaataaa aaaacggagg agtgctttat gaaagcctat
    13981 acttatgtta aaccaggact tgcttctttt gttgatgtag acaaaccagt tattcgcaag
    14041 ccaacagacg ctattgtgcg tattgtaaaa accactattt gtggaacaga cctccatatt
    14101 atcaaagggg atgttcctac ttgccaaagt ggtaccattc ttggccacga agggattggg
    14161 attgttgaag aagttgggga aggagtttcc aacttcaaaa aaggtgacaa ggtcttgatt
    14221 tcttgcgtct gtgcctgtgg taaatgctac tactgtaaaa aaggaattta tgctcactgt
    14281 gaagacgaag ggggctggat tttcggtcac ttgattgatg gtatgcaggc tgaatatcta
    14341 cgtgtccctc atgcagataa tactctttac catactccag aagacttgtc agatgaagct
    14401 ttggttatgc tgtcagacat tctgcctact ggatatgaaa ttggtgtctt aaaagggaaa
    14461 gtagaacctg gttgcagcgt agccattatt ggttcaggtc cagttggatt ggctgctctt
    14521 ttaacagccc aattctattc accagctaaa ttgattatgg tagacctaga cgataaccgc
    14581 ttggaaactg ccctatcatt cggtgcgact cataaggtta attcttcaga ccctgaaaaa
    14641 gccattaaag aaatttatga tttgacagat ggtcgtggtg tggatgtcgc tatcgaagct
    14701 gttggtattc ctgcaacatt tgatttctgt caaaagatta tcggtgtaga cggaacggtt
    14761 gccaactgtg gtgtgcatgg taaaccagtt gaattcgatt tagataaact ttggattcgc
    14821 aacatcaatg taacaactgg tttggtatct acaaatacga ctccacaatt gttgaaagcg
    14881 cttgaaagtc ataagattga accagaaaaa ttggtaactc actatttcaa actcagtgaa
    14941 attgaaaaag cctacgaagt cttcagtaag gcagcagacc accatgccat taaggtcatt
    15001 atcgaaaacg atatctcaga agcctaagta gtaaaaatat ttttgtacat aagtaaatag
    15061 aaattcagtc atccatcaga tggctggatt ttttatcaaa aaattaagaa atgagcatat
    15121 ttctttcctt gtctggcgga attggttata atatacggta caaaggaatg aatgaatatg
    15181 tatcgtgtta tagaaatgta cggagatttt gaaccgtggt ggttcttaga aggttgggaa
    15241 gaagatattg tagcaagtag aaaatttgac cagtattatg atgctctcaa atactacaaa
    15301 acttgctggt ttagattgga acaagaatcc cctctttata aaagtagaag cgacttgatg
    15361 accatttttt gggacccgga agaccaacgc tggtgtgatg aatgtgatga gtatttacaa
    15421 caataccatt ctttggctct tttgcaggat gagcaggtta tcccagacga aaaactacgc
    15481 tcaggctatg aaaaacaaac cagtcaggaa aggaatcgtt cttgccgtat gaaattaaaa
    15541 tagagaaaag taactttttt ggagttgctt tttttatttt tctaacgctt tgcgaatagt
    15601 ataggtgagg aggtaagtat ggttcaagaa attgcacaag aaatcattcg ctcggctcgg
    15661 aaaaaagggg cgcaagacat ttattttgtc cccaagttag acgcctatga gcttcatatg
    15721 agggtaggag acgagcgctg taaaattggt agctatgatt ttgaaaagtt tgcagccgtt
    15781 atcagtcact ttaagtttgt ggcgggtatg aatgtgggag aaaaaagacg tagtcaactg
    15841 ggttcctgtg attatgccta tgaccagaag atggcgtctc tacgtttatc tactgtaggc
    15901 gattatcggg ggcatgagag tttggttatc cgtttgttgc acgatgagga gcaggacttg
    15961 catttttggt ttcaggatat tgaagaatta ggcaagcagt acaggcaacg gggactctat
    16021 ctttttgctg gtccggttgg gagtggtaag acgaccttga tgcatgaatt gtccaagtca
    16081 ctctttaaag gacagcaagt tatgtccatc gaagatcctg tcgaaatcaa gcaggacgac
    16141 atgcttcagt tgcagttgaa cgaagcaatc ggtctaacct atgaaaatct aatcaaactt
    16201 tccttgcgtc atcgaccaga tctcttgatt atcggagaaa ttcgtgacat cgagacggcg
    16261 cgtgcagtgg tcagagctag tttgacaggt gcgacagtct tttcaaccat tcacgccaag
    16321 agtatccgag gtgtttatga gcgtctgctg gagttgggtg tgagtgaaga agaattggca
    16381 gttgttctgc aaggagtctg ctaccagaga ttaatcgggg gaggaggaat cgttgacttt
    16441 gcaaacagag attatcaaga acaccaagca gccaagtgga atgagcaaat tgaccagctt
    16501 cttaaagatg gacatatcac aagtcttcag gctgagacgg aaaaaattag ctacagctaa
    16561 gcaaaaaaat atcatcaccc tatttaacaa tctcttttct agcggttttc atctggtgga
    16621 gactatctcc tttttagata ggagttcctt gttggacaag cagtgtgtga cccagatgcg
    16681 tacaggcttg tctcagggga aatcattctc agaaatgatg gaaagtttgg gatgttcaag
    16741 taccattgtc actcagttat ctctagctga agttcatggc aatcttcacc tgagtttggg
    16801 aaagatagaa gaatatctag acaatctggc caaggtcaag aaaaagttaa ttgaagtagc
    16861 gacctatcct ttgattttgc tgggttttct tctcttaatt atgctggggc tacggaatta
    16921 cctgctccca caactggata gtagcaatat tgccacccga attatcggta atctgccaca
    16981 aatttttcta ggcatggtag ggcttgtttc cgtgcttgcc cttttagcac taacttttta
    17041 taaaagaagt tctaagatga gtgtcttttc tatcttagca cgccttccct ttattggaat
    17101 ctttgtgcag acctacttga cagcctatta tgcacgtgaa tgggggaata tgatttcaca
    17161 gggaatggag ctgacgcaga tttttcaaat gatgcaggaa caaggttccc agctctttaa
    17221 agaaatcggt caagatctgg ctcaaaccct gaaaaatggc cgtgaatttt ctcagacgat
    17281 aggaacctat cctttcttta ggaaggaatt gagtctcatc atagagtatg gggaagttaa
    17341 gtccaagctg ggtagtgagt tggaaatcta tgctgaaaaa acttgggaag ccttttttac
    17401 ccgagtcaac cgcaccatga atttggtgca gccactggtt tttatctttg tggcactgat
    17461 tatcgtttta ctttatgcgg caatgctcat gcccatgtat caaaatatgg aggtaaattt
    17521 ttaaaatgaa aaaaatgatg acattcttga aaaaagctaa ggttaaagct tttacattgg
    17581 tggagatgtt ggtggtcttg ctgattatca gcgtgctttt cttgctcttt gtacctaatc
    17641 tgaccaagca aaaagaagca gtcaatgaca aaggaaaagc agctgttgtt aaggtggtgg
    17701 aaagccaggc agaactttat agcttggaaa agaatgaaga tgctagccta agcaagttaa
    17761 aagaagatgg acgcatcacg gaagaacagg ctaaagctta taaagaatac aatgataaaa
    17821 atgtgggagc aaatcgtaaa gtcaatgatt aaggccttta ccatgctgga aagtctcttg
    17881 gttttgggtc ttgtgagtat ccttgccttg ggcttgtccg gctctgttca gtccactttt
    17941 gcggcggtag aggaacagat tttctttatg gagtttgaag aactctatcg ggaaacccaa
    18001 aaacgcagtg tagccagtca gcaaaagact aatctaaatt tagatgggca gacgcttagc
    18061 aatggcagtc aaaagttgac agttcctaaa ggaattcagg caccatcagg ccaaagtatt
    18121 acatttgacc gagctggggg caattcgtcc ctggctaagg ttgaatttca gaccagtaaa
    18181 ggagcgattc gctatcaatt atatctagga aatggaaaaa ttaaacgcat taaggaaaca
    18241 aaaaattagg gcagtgattt tactggaagc agtagtcgct ctagctatct ttgccagcat
    18301 tgcgaccctc cttttgggac aaattcaaaa aaataggcaa gaggaagcaa aaatcttgca
    18361 aaaggaagaa gtcttgaggg tagctaagat ggccctgcag acggggcaaa atcaggtaag
    18421 catcaacgga gttgagattc aggtattttc tagtgaaaaa ggattggagg tctaccatgg
    18481 ttcagaacag ttgttggcaa tcaaagagcc ataaggtcaa ggcttttacc ttgttagaat
    18541 ccctacttgc cctcattgtc atcagtgggg gattactcct ttttcaaact atgagtcagc
    18601 tcctcatttc agaagttcgc taccagcaac aaagcgagca aaaggagtgg ctcttgtttg
    18661 tggaccaact tgaggcagaa ttagaccgtt cgcagttcga aaaagtagaa ggcaatcgcc
    18721 tatacatgaa gcaagatggc aaggacatcg ccatcggtaa gtcaaagtca gacgattttc
    18781 gtaaaacgaa tgctcgtggt cgaggttatc agcctatggt ttatggcctc aaatcagctc
    18841 agattacaga ggacaatcaa ctggttcatt ttcgtttcca gtttcaaaaa ggcttagaaa
    18901 gggagttcat ctatcgtgtg gaaaaagaaa aaagttaagg caggtgttct cctctacgca
    18961 gtcaccatag cagccatctt tagtcttttg ttgcaatttt atttgaaccg acaagtcgcc
    19021 cactatcaag actatgcttt gaataaagaa aaattggttg cttttgctat ggctaaacga
    19081 accaaagata aggttgagca agaaagtggg gaacaggttt ttaatctagg tcaggtaagc
    19141 tatcaaaaca agaaaactgg cttagtgacg agggttcgta cggataagag ccaatatgag
    19201 tttctgtttc cttcagtcaa aatcaaagaa gagaaaagag ataaaaagga agaggtagcg
    19261 accgattcaa gcgaaaaagt ggagaagaaa aaatcagaag agaagcctga aaagaaagag
    19321 aattcctagt caattcaact ataatgcgtt gaatccagaa tagtccactg tagtttctag
    19381 aaaattgctg gaaatggatg ttaagctcca attcatttgt ttatatctta tttcagttta
    19441 ctatactttg tgctaaatta aagatatgaa acatgatttt aaccacaaag cagaaacttt
    19501 cgatttccct aaaaatatct tcctcgcaaa cttggtatgt caagcagccg agaaacagat
    19561 tgatcttcta tcatacaaag aaattttaga tttcggtggt ggcacgggtc tattagcctt
    19621 gcccctaacc cctagccaag caggctaagt cagtcactct tgtagacatt tctgagaaaa
    19681 tgttggagca agctcgtttg aaagtggagc agcaagcaat caagaatatc cagtttttgg
    19741 agcaagattt accgaaaaat cccttggaga aagagtttga ttgccttgct gttagtcggg
    19801 ttcttcatca tatgcctgat ttggatgcgg ctctctcact gtttcatcaa catttgaagg
    19861 aagatgggaa actcatcatt gctgatttta ccaagacaga agctaatcat catggatttg
    19921 atttagctga actggaaaac aagctaattg agcatggttt ttcatctgtg catagtcaga
    19981 ttctctatag cgctgaagac ctgtttcaag gaaatcactc agaattcttt ttaatagtag
    20041 cccaaaaatc actcgcctag tcagggagtg atttttctat aagaatggaa aaaagaaggg
    20101 aaatttgata agataggaat atggattttg aaaaaattga acaagcttat acctatttac
    20161 tagagaatgt ccaagtcatc caaagtgatt tggcgaccaa cttttatgac gccttggtgg
    20221 agcaaaacag catctatctg gatggtgaga ctgagctaga acaggtcaaa gacaacaatc
    20281 agacccttaa gcgtttagca ctacgcaaag aagaatggct caagacctac cagtttctct
    20341 tgatgaaggc tgggcaaaca gaacccttgc aggccaatca ccagtttaca ccggatgcta
    20401 ttgctttact tttggtgttt attgtggaag agctgtttaa agaggaggaa attactatcc
    20461 tcgaaatggg ttctgggatg ggaattttgg gcgctacttt cttgacctcg cttactaaaa
    20521 aggtggatta tttgggaatg gaagtggatg atttgctgat tgatttggca gctagcatgg
    20581 cagatgtaat tggtttgcag gctggctttg tccaaggaga tgccgttcgt ccacaaatgc
    20641 tcaaagaaag tgatgtggtc atcagcgact tgcctgttgg ctattatcct gatgatgccg
    20701 ttgcgtcgcg ccatcaagtt gcttctagtc aagaacatac ttacacccat cacttgctca
    20761 tggaacaagg acttaagtac ctcaagtcag acggatacgc tatttttcta gctccgagtg
    20821 atttgttgac cagtcctcaa agtaatttgt tgaaagtctg gttgaaagag gaggcaagtc
    20881 tggttgctat gattagttta cctgaaaatc tctttgctaa tgctaaacaa tctaagacta
    20941 tttttatcct acagaagaaa agtgaaatag cagtagagcc ttttgtttat ccacttgcta
    21001 gcttgcaaga tgcaagtgtt ttaatgaaat ttaaagaaaa ttttcaaaaa tggactcaag
    21061 gtactgaaat ataaaataga ttttgttata atagttgaaa acgcttaaaa aggggtatca
    21121 tgttatgaca aaaacaattg caatcaatgc aggaagttca agtttgaaat ggcaattata
    21181 cttaatgcca gaagaaaaag tattggcgaa aggtttgatt gaacgtatcg gtttgaaaga
    21241 ttcaatttca actgtaaaat ttgacggccg ttctgaacaa caaattttgg atattgaaaa
    21301 tcatacacaa gctgttaaaa ttttattgga tgacttgatt cgtttcgata ttatcaaggc
    21361 ttatgacgag attacaggtg ttggacatcg tgttgttgct ggtggagaat atttcaaaga
    21421 atcaacagtt gttgagggag atgttttaga aaaagttgaa gagttgagtt tgttggctcc
    21481 tctacacaac ccggcaaatg cagcaggtgt tcgtgccttc aaggaattgt tgccagacat
    21541 taccagtgta gttgtttttg atacttcctt ccacacaagt atgccagaga aagcttatcg
    21601 ctaccctcta ccaacaaaat attacacaga aaacaaggtt cgtaaatacg gtgctcatgg
    21661 tacaagtcac cagtttgtag caggagaagc tgcaaaactc ttgggacgtc cattagaaga
    21721 cttgaagtta attacctgtc atattggtaa cggaggctca attacagctg tgaaagccgg
    21781 caaatctgta gacacttcta tggggttcac tcctcttggt ggtattatga tgggaacgcg
    21841 tacaggggat attgatccag ctatcattcc ttatttaatg caatatacag aggattttaa
    21901 cacaccagaa gatatcagtc gtgttcttaa ccgtgaatca ggtcttttgg gagtttctgc
    21961 taattctagc gatatgcgcg atatagaagc agctgtagca gaagggaatc acgaggctag
    22021 cttggcttat gaaatgtatg ttgaccgtat ccaaaaacat atcggtcagt accttgcagt
    22081 gctaaatgga gcagatgcca ttgttttcac agcaggtgtc ggtgaaaatg cagagagttt
    22141 ccgtcgtgat gtaatctcag ggatttcgtg gtttagttgt gatgttgatg atgaaaagaa
    22201 tgtctttggc gttacaggag acatctcaac agaggcagct aaaatccgtg tcttggttat
    22261 tccaacagat gaagaattag tcattgcccg tgacgttgaa cgcttgaaaa aataagtgaa
    22321 actaaaaaaa tattcaatac aaggagttgg gaaagttatt tttccagctt ctttttctga
    22381 tgaaattgtc caaaaccttg ctatgattgg cttttttgaa aaatatggta taatagtagt
    22441 aatttaatag atggagttga gttttgaaga aaaactttcg tgtaaaaaga gagaaagatt
    22501 ttaaggcgat tttcaaggag gggacaagtt ttgctaatcg caaatttgtg gtctaccaat
    22561 tagaaaacca gaaaaaccat tttcgagtag gtctatcagt tagcaaaaaa ctggggaatg
    22621 ccgtcactag aaatcaaatt aagcgacgga ttcggcatat tatccagaat gcaaaaggga
    22681 gtctggtaga agatgtcgac tttgttgtca ttgctcgaaa aggagtcgaa accttgggat
    22741 acgcagagat ggagaaaaat ctactccatg tattaaaatt atcaaagatt taccgggaag
    22801 gaaatgggag tgaaaaagaa actaaagttg actagtttgc taggactgtc tctgttaatc
    22861 atgacagcct gtgcgactaa tggggtaact agcgatatta cagccgaatc ggctgatttt
    22921 tggagtaaat tggtttactt ctttgcggaa attattcgct ttttatcgtt tgatattagt
    22981 atcggagtgg ggattattct ctttacggtc ttgattcgta cagtcctctt gccagtcttt
    23041 caggtgcaaa tggtggcttc taggaaaatg caggaagctc agccacgcat taaggcgctt
    23101 cgagaacaat atccaggtcg agatatggaa agcagaacca aactagagca ggaaatgcgt
    23161 aaagtattta aagaaatggg tgtcagacag tcagactctc tttggccgat tttgattcag
    23221 atgccggtta ttttggccct gttccaagcc ctatcaagag ttgacttttt aaagacaggt
    23281 catttcttat ggattaacct tggtagtgtg gatacaaccc ttgttcttcc gattttagca
    23341 gcagtattca cctttttaag tacttggttg tccaacaaag ctttgtctga gcgaaatggc
    23401 gctacgactg cgatgatgta tgggattcca gtcttgattt ttatctttgc agtttatgcg
    23461 ccaggtggag tcgccctata ctggacagtg tctaatgctt atcaagtctt gcaaacctat
    23521 ttcttgaata atccattcaa gattatcgca gagcgcgagg ccgtagtaca ggcacaaaaa
    23581 gatttggaaa atagaaaaag aaaagccaag aaaaaggctc agaaaacgaa ataaataagg
    23641 aggaatctgg taatggtagt atttacaggt tcaactgttg aagaagcaat ccagaaagga
    23701 ttgaaagaat tagatattcc aagaatgaag gctcatatca aagtcatttc tagggagaaa
    23761 aaaggctttc ttggtctatt tggtaaaaaa ccagcccaag tggatattga agcgattagt
    23821 gaaacgactg ttgtcaaagc aaatcaacag gtagtaaaag gcgttccgaa aaaaatcaat
    23881 gatttgaacg agcctgtgaa gacggttagt gaagaaaccg ttgaccttgg tcatgtggtt
    23941 gatgctatta aaaaaataga ggaagaaggt caaggtattt ctgatgaagt caaggctgaa
    24001 atcttaaaac atgaaagaca tgccagcact atcttagaag aaactggtca cattgagatt
    24061 ttaaatgaac ttcaaatcga ggaagcgatg agggaagaag caggcgctga tgaccttgaa
    24121 actgagcaag atcaaactga aaatcaagac ttgaaagaga tgggcttgaa ggtcgagcaa
    24181 agttatgata ttgcccaggt ggctacggat gtgactgctt atgttcaaac gattattgat
    24241 gacatggatg ttgaggctac actttcaaat gattataacc gtcgtagcat caatttgcaa
    24301 attgatacta acgaaccagg tcgtattatc ggctaccatg gtaaagtctt gaaggccttg
    24361 caactgttgg ctcaaaatta tctttacaac tgctattcaa gaaccttcta tatcactatt
    24421 aatgtcaatg attatgttga acaccgtgca gaagtcttgc agacctatgc gcaaaaattg
    24481 gcgattcgtg ttttagaaga agggcgcagt catcaaacag atccaatgtc gaatagtgaa
    24541 cgcaagatta tccaccgtat tatttcacgt atggatggcg tgaccagtta ctctgaaggt
    24601 gatgagccaa atcgctatgt cgttgtagat acagaataag taaaatcagg gttgacctga
    24661 ttttttgcta gctagaggag gttaaactga tgttgaataa gataagagac tatctagact
    24721 tttctggttt gcagtaccgt agtcctgata aagcgggagc agagcgagag aagatgctgg
    24781 cgttccgcca caaaggacaa gaggcccgaa aggcttttac agaactggcc aaagcctttc
    24841 aagcaagcca tccagaatgg caactccaac agactagtca gtggatgaat caggcccagc
    24901 gtttgagacc acatttttgg gtttatctac agagagacgg acaagtgaca gaacctatga
    24961 tggccttacg tttgtatggg acatctactg actttggaat ttctttggaa gtcagtttca
    25021 tcgaacgtaa gaaggatgag caaacactgg gcaagcagac caaagtttta gacattccaa
    25081 ccgttaaagg gatttattat ctaacctact ctaatggtca aagtcaacgg tgggaggcga
    25141 atgaagaaaa gcgtcgtact ttacgcgaga aggtgagaag tcaagaagtt cgaaaagttt
    25201 tagtgaaggt agatgttcct atgacagaaa attcgtctga agaagaaatc gtagaaggct
    25261 tattgaagtc ttattctaaa attcttccct attatctagc tacgagaaaa taagataatt
    25321 tgtaaaacat cataaatcat acagtccaag agtgaacagt ccgctgtgta attcttggtc
    25381 tttttgtttg cgctttcgca ttatataata aacttacaaa aacaattcaa aaggagaaca
    25441 attatggaag tcgtttcaag tgttctaaat tggttttcta gcaatatttt gcagaatccc
    25501 gcatttttcg taggtttatt ggtgttgata ggatatgcac ttttgaaaaa acctgcccat
    25561 gacgtttttt cagggtttgt taaagcaaca gtagggtata tgttgcttaa cgtgggtgct
    25621 ggtggtttgg ttacaacctt tcgtccaatc ttagcagctc ttaactacaa attccaaatt
    25681 ggtgcagcgg ttatcgaccc ttactttgga cttgctgcag caaacaacaa aattgcagca
    25741 gagtttccag attttgttgg aactgcaact acagctctat tgattggttt tggaataaat
    25801 atcttgctcg tagctcttcg aaagattacg aaggtaagaa ccctctttat tactggtcac
    25861 atcatggtac aacaagctgc aacagtatct cttatggttc tattcttagt accacaattg
    25921 cgcaatgctt acggtacagc agcgattggt atcatctgtg gactttactg ggcagttagt
    25981 tcaaatatga ctgttgaggc aactcaacgc ttgactggtg gtggcggatt tgcgattggt
    26041 caccaacagc aatttgcaat ctggtttgta gataaagtag caggacgctt tggtaagaaa
    26101 gaagaaagtt tagacaatct taaattacct aagttcctct caatcttcca cgatacagtt
    26161 gttgcatctg ctaccttgat gctcgtattc ttcggagcca ttcttttaat cttgggtcca
    26221 gacattatgt ctaataaaga agtcatcact tcaggaactc tattcaatcc tgctaaacaa
    26281 gatttcttta tgtacattat ccaaacagcc tttaccttct cagtttactt gttcgttttg
    26341 atgcaaggtg tccgaatgtt cgtatctgag ttgacaaacg ccttccaagg tatttcaaac
    26401 aaattgttgc caggttcatt cccagcggtt gacgttgcag cttcttatgg atttggttct
    26461 ccaaatgctg tcctgtcagg atttatcttt ggtttgattg gtcaattgat tacaattgtt
    26521 ttgctcatcg tctttaaaaa tccgattctt attattacag gatttgtacc agtgttcttt
    26581 gacaatgcag ccattgcggt ctacgctgat aaacgcggcg gatggaaagc ggctgttatc
    26641 ctttccttta tatcaggtgt ccttcaagtt gctctaggag ctctttgtgt ggcccttctc
    26701 gatttggcat cttatggtgg ctaccatgga aatatcgact ttgaattccc atggcttgga
    26761 tttggatata tcttcaaata ccttggtatt gttggttatg tacttgtgtg tctcttcttg
    26821 cttgttattc ctcaacttca atttgccaaa gcaaaagata aagagaaata ttacaacggt
    26881 gaagttcaag aagaagctta gtatctagaa aaggagaaat aaaatggtta aagtattagc
    26941 agcgtgcgga aatggaatgg gttcatcaat ggttatcaag atgaaggttg aaaatgctct
    27001 ccgtaagctt aatcaaacag attttacagt caattcatgc agtgtcggtg aagctaaagg
    27061 tttagcagta ggatatgaca tcgtaatcgc ttctcttcat ttgattcaag aattggaagg
    27121 gcgaactaat gggaagttaa ttgggcttga taacttgatg gatgataaag aaatcaccga
    27181 aaaactcagt caagcactac agtaaaaggt tggagggggc tggacagaaa ctgagagtta
    27241 tcgtttctgt ccttctccct ctttaaataa aggaggcaga tatgaattta aaacaagctt
    27301 taattgacaa cgactcgatc cgactaggtt tagaggctaa cgattggaaa gaagcagtca
    27361 aggtagcagt agatcccttg attgaaagtg gggcaatttt gccagagtat tacgatgcta
    27421 tcattgaatc gactgaagag tatgggcctt actatatctt gatgccaggt atggctatgc
    27481 cccacgctag acctgaagct ggtgtgcaaa gtgatgcctt ttcattgatt accttacaaa
    27541 atcctgttgt attttcagat gggaaagagg tatctgtttt gttggcacta gcagcaacaa
    27601 gttcaaaaat tcacacaagt gtagccattc cacaaattat tgccctgttt gaattagaag
    27661 attctattgc acgtttacag gcttgccaga ctaaagaaga tgtcttggct atgattgaag
    27721 aatctaagga tagcccttat ctcgaaggat tggatttgga aagttagaaa gaggaataaa
    27781 gaaatgacaa aaagaatacc taatttacaa gttgcattag accattcaga cttgcaagga
    27841 gcgattaaag cagctgtttc tgttggtcag gaagtagata ttatcgaagc tggaactgtt
    27901 tgcttgcttc aagttggaag tgaactggct gaagtcttgc gtagcctttt cccagataag
    27961 attattgtgg cagacacaaa atgtgctgat gctggtggaa cagttgctaa aaataatgcg
    28021 gttcgtggag cagactggat gacttgtatc tgttgtgcaa ccatccctac tatggaagca
    28081 gctctaaagg ctatcaagac tgaacgagga gaacgaggcg aaatccagat cgagctttat
    28141 ggcgattgga cttttgaaca agctcagctt tggctagatg caggtatctc acaagctatt
    28201 tatcaccaat ctcgtgatgc tcttcttgct ggtgaaactt ggggtgaaaa agaccttaat
    28261 aaggttaaaa aactcattga catgggcttc cgtgtatctg taacaggtgg tctagatgta
    28321 gatactctca aactctttga aggtgttgat gtctttacct ttatcgcagg tcgtggaatt
    28381 acagaggctg cggatccagc aggagcagcg cgtgccttca aggatgaaat caaacgaatt
    28441 tgggggtaaa tcatggtacg tccaattgga atttatgaaa aggcaacccc aacacacttt
    28501 acttggctag aacgtttaaa ttttgccaag gagttaggct ttgattttgt cgagatgtct
    28561 attgacgaac gtgacgagcg tttagcaaga cttgactgga gtaaggaaga acgcttggaa
    28621 gttgtcaaag aaatctatga aactggtgtt cgtattcctt ctatctgttt ttcaggccat
    28681 cgtcgctacc cattgggatc aaaagatcca gttctagagg aaaaatctct agaactcatg
    28741 aaaaaatgta tcgaattagc tcaagacttg ggagttcgta cgattcaatt agctggttac
    28801 gatgtttact atgaggaaaa gtcaccccag acacgccaac gttttatcaa aaatttgaga
    28861 aaagcctgtg actgggctga agaagctcag gtggtacttg ctattgaaat tatggatgat
    28921 cctttcatca gtagcatcga aaaatatttg gctatagaaa aagagattga ctctcccttc
    28981 ctctttgtat atccagatat tggtaatgtg tctgcatggc ataatgatat ctatagtgag
    29041 ttttatcttg gtcatcatgc catcgcagct ctccatctca aggatactta tgcagtgaca
    29101 gaaagttcaa agggccagtt ccgagatgta cctttcgggc aaggttgtgt caaatgggaa
    29161 gaagctttcg atattttaaa ggaaaccaat tataatggac ctttcctaat cgaaatgtgg
    29221 tctgaaaatt gtgaaacagt agaagaaaca cgcgcagcca ttcaagaggc gcaagctttt
    29281 ctctatccac tcattaagaa agcaggtttg atgtaagatg aatcaagtaa tcaatgctat
    29341 gcgtaaacga gtctgtgatg ccaatcaatc attgccaaaa catggacttg tcaaatttac
    29401 ctgggggaat gtatctgaag tcaatcgcga actcggtgtc attgttatca aaccatcagg
    29461 cgtggattat gacgaattga cacctgaaaa catggtagtg actgatctag atggtaagat
    29521 cctagaaggg gatttaagac catcttccga cctcccaact catgtgcaat tatataagac
    29581 ttggtcagaa attggtagtg tggttcacac ccattcgaca gaagctgttg gttgggctca
    29641 ggcaggtcgt gatattcctt tctacggaac aacccatgca gattatttct acggttcaat
    29701 cccttgcgcc cgtagtttga ccaaggacga agtagaagtg gcctatgaaa aagatactgg
    29761 cctggttatc gtagaagagt ttgaacatcg cggacttaac ccggttgaag taccaggaat
    29821 tgttgtacgc aatcacggtc cattcacctg gggcaaaaat ccagagaatg ctgtttatca
    29881 ctctgtcgta ctagaggaag tatcaaagat gaatcgcttt acagaacaaa tcaatccaag
    29941 agttggacct gctccccagt acatactaga aaaacactac caacgtaaac atggaccaaa
    30001 tgcttattat ggtcaaaagt aagaacgatg aaggaggaga aaaagataaa tttagctcct
    30061 ctttttacat ttgattttta ttgagagtaa agttggagtt gaagtaattt tgaaagattt
    30121 tttagaaata gcgcttgata tatatatggt aaaataaaaa gaattgctgt gatatcaata
    30181 gatttggggg attttttaat atggtactgg ataaggcaag ttgtgatttg cttcaatatt
    30241 tgatggatca agaaacgtcc aaaacgatta tggcgatttc gaaagatttg aaagagtcaa
    30301 gaaggaaaat ttattatcac attgacaaaa tcaatgctgc tctggttgac gaggcgcttc
    30361 acatcattag tattccacga attggtattc acttaacgga agagcagaga gatgcttgtt
    30421 gtaaactatt atcggaagta gattcgtacg attatatcat gagtgcgcat gaacgtatga
    30481 tgataatgtt actatggata ggtatttcta aagaacgtat tacgattgaa aaattgatag
    30541 agttaacaga ggtatctagg aatactgttc tcaatgattt gaatagtatt cgttatcaac
    30601 taactttgga acaatatcag gtgatcttgc aagtgagcaa gtcacaggga taccaccttc
    30661 atgcccaccc tcttaataaa attcagtatc ttcaatcgct tctatatcat atttttatgg
    30721 aagaaaatgc cacttttgta tctattttag aagataagat gaaagagagg ttagatgatg
    30781 agtgtttgct ttctgttgaa atgaaccaat tttttaagga acaggttcct ttagttgaac
    30841 aagatttagg gaagaaaata aaccatcatg aaataacttt tatgttgcag gttctacctt
    30901 atttgctgtt aagctgtcat aatgttgaac agtatcaaga aagacatcag gatatagagc
    30961 aagaattttc tttgataaga aaaagaatag agtatcaggt gtctaagaaa ttaggagaac
    31021 ggttgtttca aaagtttgaa atttctttgt caggacttga agtttctctt gtagctgttc
    31081 tcctcctctc ctatcgtaaa gatttggata ttcatgcaga aagtgatgat tttcggcaat
    31141 taaaacttgc tttagaagaa tttatctggt attttgaatc acaaatccga atggagattg
    31201 agaacaagga tgatttgtta cgaaatttga tgatccactg taaagccttg ttatttagaa
    31261 agacttacgg tattttttct aaaaatcctc taacaaaaca aattcgatcc aagtatggag
    31321 aattattttt agtcactaga aaatctgcgg aaattttaga aggagcatgg tttattcggc
    31381 taacagacga tgatattgcc tatttgacga ttcatattgg aggattttta aagtatacac
    31441 catcgtctca aaaaaatatg aaaaaagttt atctcgtttg tgatgaaggt gttgcggttt
    31501 cgagactttt gctgaaacaa tgcaaacttt attttccaaa tgagcaaatt gacactgtat
    31561 ttacaacaga acaatttaag agtgtggaag atattgcaca agttgatgta gtgattacta
    31621 ctaatgatga tttggatagc agatttccga ttttaagggt taatcctatc cttgaagcag
    31681 aagatatttt gaaaatgcta gactatctta aacacaatat atttcgtaat gagagcaaaa
    31741 gtttcagtga aaatctttct agtcttattt cgtcttatat tgtagacagc aagttggcta
    31801 gtaagttcca agaagaggtt caaacactta taaatcaaga aatagtagtt caagcttttt
    31861 tggaagatat ttgaaggaca gtccaatgat gaacacaaac ctgtgttttt cttggtcttt
    31921 tttagtgttt tgaagggtgg tatactaatc tcaaagataa caattatatc caaaggaggc
    31981 aacatatgcc aaacgtcaaa gaaattacaa gagagttatg gattttagcc actttcccag
    32041 agtggggaac atggttgaac gaagaaatcg aagaagaagt cgtacctgaa ggcaactttg
    32101 ccatgtggtg gctaggcaac tgtggtactt ggattaagac accagctggt gctaacgttg
    32161 tcatggacct ttggtcaaac cgtggaaaat caaccaaaaa agtgaaagat atggttcgtg
    32221 ggcaccaaat ggcaaatatg gcaggtgttc gtaagttgca accaaacttg cgtgttcagc
    32281 caatggttat cgatccattt gctatcaacg aactagacta ttacttagtt tcacacttcc
    32341 acagtgatca tatcgaccca tacacagctg cagcaattct caacaatcct aagttagagc
    32401 atgttaagtt tatcggtcct taccactgtg gacgaatctg ggaaggatgg ggtgttccaa
    32461 aagaacgtat caacgttgtt aaaccaggtg acactatcga attaaaagat atgaagattc
    32521 atgcagtaga atcatttgac cgtacttgct tggtaactct cccagtgaac ggtgctgatg
    32581 agacaggcgg tgaacttgct ggcttgactg ttacagatga agaaatggct caaaaggctg
    32641 ttaactatat ctttgaaaca ccaggtggaa ccatctatca tggtgcagat tctcacttct
    32701 caaactattt tgcaaaacat ggtaaagact ttaaaattga tgttgctttg aataactatg
    32761 gtgaaaatcc ggtaggtatc caagacaaaa tgacatctat cgaccttctt cgtatggcag
    32821 aaaatctgcg taccaaagtc attatcccag ttcactatga tatctggtct aacttcatgg
    32881 cttctactaa tgagattcta gaactttgga aaatgcgaaa agatcgcttg caatacgatt
    32941 tccatccatt tatctgggaa gttggcggta agtacactta tcctcaagat caacacttag
    33001 tagaatacca tcatccacgt ggttttgatg attgttttga acaagactct aacattcaat
    33061 ttaaagcttt gctataatat aaaaatattc tttggaggtt atccgtatgt tgcatgatac
    33121 ggataatttt catataatag taaaatagaa tgtgtgattc aataatcacc tcaaatagaa
    33181 aggaaattct atgtcaaatc tatctgttaa tgcaattcgt tttctaggta ttgacgccat
    33241 taataaagcc aactcaggtc atccaggtgt ggttatggga gcggctccga tggcttacag
    33301 cctctttaca aaacaacttc atatcaatcc agctcaacca aactggatta accgcgaccg
    33361 ctttattctt tcagcaggtc atggttcaat gctcctttat gctcttcttc acctttctgg
    33421 ttttgaagat gtcagcatgg atgagattaa gagcttccgt caatggggtt caaaaacacc
    33481 aggtcaccca gaatttggtc atacggcagg gattgatgct acgacaggtc ctctagggca
    33541 agggatttca actgctactg gttttgctca agcagaacgt ttcttggcag ccaaatataa
    33601 ccgtgaaggc tacaatatct ttgaccacta tacttacgtt atctgtggag acggagactt
    33661 gatggaaggt gtctcaagcg aggcagcttc atatgcaggc ttgcaaaaac ttgataagtt
    33721 ggttgttctt tatgattcaa atgacatcaa cttggatggt gagacaaagg attcctttac
    33781 agaaagtgtt cgtgaccgtt acaatgccta cggttggcat actgccttgg ttgaaaatgg
    33841 aacagacttg gaagccatcc atgctgctat cgaaacagca aaagcttcag gcaagccatc
    33901 tttgattgaa gtgaagacgg ttattggata tggttctcca aacaaacaag gaactaatgc
    33961 tgtacacggc gcccctcttg gagcagatga aactgcatca actcgccaag ccctcggttg
    34021 ggactacgaa ccatttgaaa ttccagaaca agtatatgct gatttcaaag aacatgttgc
    34081 agaccgtggc gcatcagctt atcaagcttg gactaaatta gttgcagatt ataaagaagc
    34141 tcatccagaa ctggctgcag aagtagaagc catcatcgac ggacgtgatc cagtcgaagt
    34201 gactccagca gacttcccag ctttagaaaa tggtttttct caagcaactc gtaattcaag
    34261 tcaagatgcc ttgaatgttg tggcagctaa attaccaacc ttcctaggtg gatcagctga
    34321 ccttgctcac tcaaacatga cttatatcaa gacagatgga cttcaagacg atgccaatcg
    34381 cttgaatcgt aacattcagt ttggtgttcg tgaatttgca atgggaacaa tcttgaacgg
    34441 gatggccctt catggtggac ttcgtgtata cggtggaact ttcttcgtct tctctgacta
    34501 tgtgaaggca gctgtccgct tgtcagcctt acaaggactt cctgtgactt atgtctttac
    34561 ccatgattca atcgcagttg gggaagatgg tccgactcac gaaccagttg agcatttagc
    34621 aggtcttcgt gctatgccaa atctaaatgt tttccgtcca gcagatgcgc gtgaaacgca
    34681 agcagcttgg taccttgcag tgacaagtga gaaaacacca actgcccttg tcttgacacg
    34741 tcaaaacttg actgttgaag atggaacaga cttcgataag gttgctaaag gtgcttatgt
    34801 tgtatatgaa aatgcagccg actttgatac catcttgatt gcgacaggtt cagaggttaa
    34861 tcttgctgtc tcagctgcta aagaattggc tagtcaaggc gaaaaaatcc gcgtagtcag
    34921 catgccatct acagatgtct ttgataaaca agatgcagct tacaaggaag aaattcttcc
    34981 aaatgcagtc cgccgtcgtg ttgcaattga aatgggtgca agtcaaaact ggtacaaata
    35041 tgttggtctc gatggtgccg ttctaggtat tgataccttc ggagcctctg ccccagcacc
    35101 aaaagtattg gcagaatatg gctttactgt agaaaatctt gtaaaagttg ttcgaaactt
    35161 gaaataatcc taaaaatcag agcgtaagct ctggtttttc ttaccagaaa agtaaggtac
    35221 aatcttgtaa aagtagctga aatttgatat agtagtccta tgtaaaagac aaaggagaag
    35281 acaatgaatc caaattatac atttttaatc atgcttgtag gtatgatggc cttgatgttc
    35341 tttatgcaac gttctcaaaa gaaacaagct caaaagcgta tggaaagctt aaataaacta
    35401 caaaaaggct atgaagtgat tacaatcggt ggactttatg gaacagtcga tgaagtagat
    35461 acggagaagg gaacaatagt tcttgacgta gatggagttt acttgacttt tgaactagct
    35521 gctatcaaga cagtattacc gctgaaagaa acagcttcac tagaaggcgc aattgaaaaa
    35581 taagacggga tcacgaactc ccgtttttct ataaaagaaa ggaaatggga tgaaaaaatt
    35641 agtctttgtc tgtctgggaa atatttgccg tagccctatg gccgagtttg ttatgaaatc
    35701 aatgacagat aactacgaaa tccaaagtcg agcaacttcc tcttgggaac atggcaatcc
    35761 gattcataag gggactcagg gaatttttca agagtatgag attccttatg acaagaacaa
    35821 gacatcgctt cagattagta aggaagattt tgaagccttt gattatatta tcggaatgga
    35881 cgcttcaaat atttctgact tacgtcagat gtgtccagta gactgtcaag ataagattta
    35941 ctcattttca tctgaaagtg ttccagaccc ttggtataca ggagattttg aagaaaccta
    36001 tcgacgtgtt caagagggtt gtcaagcttg gttagaacgt ttagaaaagg agagttaagg
    36061 tggaaaatcc tacgaatttt tacgaaaagt atcgtgtcta tctgactcgt ccacgtttag
    36121 agcttttggc agtagttacc attgttttct gtgctgtact cgtctttttt ctaaatattc
    36181 caggaaaagg tgtcttaaaa ctcgataatg gaacgattgt ttatgatggc agtcttgtcc
    36241 gtggtaaaat gaatggtcaa ggtaccatta ccttccaaaa tggagaccaa tatacaggtg
    36301 gcttcaacaa tggagccttc aacggaaaag gtacctttca atctaaagaa ggctggacct
    36361 acgaaggtga ttttgtaaat ggtcaggctg aaggaaaagg gaaactaaca acagaacaag
    36421 aagtcgttta tgaaggaact tttaaacaag gcgtttttca acaaaaataa agcctcctta
    36481 tccaaaggag gtattattag aaccacaagg taagcgctta cctgtaaatc cctttctttc
    36541 caaatccctc ttccaagcaa gtttgtgaaa taaaaaatat ttgaaataaa tttcacaaac
    36601 tttaaagata aaacctgata agaaaagaaa atgagaaaag tttcacaaga gtttaaaaat
    36661 tctttgtgaa atgtttatga aactgtttac aaagttgaaa taatgcgtta taataaactt
    36721 gtgaaaaaat taacaaagga tatcgttcct tgaaagctat ggaggaaaat atggctgata
    36781 aaaaaactgt gacaccagag gaaaagaaac tcgttgctga aaaacacgta gatgagttgg
    36841 ttcaaaaagc tctagttgcc cttgaagaaa tgcgtaaatt ggatcaagag caagttgact
    36901 acatcgttgc caaagcatca gtagcagctt tggatgccca cggagaattg gctttacatg
    36961 cctttgaaga aacaggacgt ggtgtatttg aagataaagc aactaagaac ttgtttgcct
    37021 gtgaacacgt agtaaacaac atgcgccaca ctaagacagt tggcgttatc gaagaagacg
    37081 atgtaacagg attgactctt attgctgaac cagttggtgt tgtttgtggt attactccaa
    37141 caacaaaccc aacatcaaca gcgatcttca aatcattgat ttcattgaag acacgtaatc
    37201 caatcgtctt tgccttccat ccatcagctc aagaatcatc agctcatgca gctcgtatcg
    37261 tccgcgatgc agctatcgca gctggtgctc ctgaaaactg tgtacaatgg attactcaac
    37321 catctatgga agcaacaagt gcccttatga accacgaagg tgttgcgaca atccttgcaa
    37381 caggtggtaa tgccatggtt aaggcggctt attcatgtgg taaaccagct cttggggtag
    37441 gtgccggaaa cgttccagct tatgttgaaa aatcagcaaa cattcgtcaa gcagcacacg
    37501 atatcgtcat gtctaaatca tttgataacg gtatggtctg tgcatctgaa caagcagtta
    37561 tcattgataa agaaatttac gatgaatttg tagcagagtt caaatcttac cacacttact
    37621 ttgtaaacaa aaaagaaaaa gctcttcttg aagagttctg cttcggtgtc aaagcaaaca
    37681 gcaaaaactg tgctggtgca aaattgaacg ctgacatcgt tggtaaacca gcaacttgga
    37741 ttgcagaaca agcaggattt acagttccag aaggaacaaa cattcttgct gcagaatgta
    37801 aagaagttgg cgaaaatgag ccattgactc gtgaaaaatt gtcaccagtt attgcagttt
    37861 tgaaatctga aagccgtgaa gatggtatta ctaaggctcg tcaaatggtt gaatttaacg
    37921 gtcttggaca ctcagcagct atccacacag ctgacgaaga attgactaaa gaatttggta
    37981 aagctgttaa agctattcgt gttatctgta actcaccttc tacttttggt ggtatcgggg
    38041 acgtttacaa tgccttcttg ccatcattga cacttggatg tggttcttac ggacgcaact
    38101 cagttgggga taacgttagt gccattaacc tcttgaatat caaaaaagtc ggaagacgga
    38161 gaaataacat gcaatggatg aaacttcctt caaaaacata ctttgaacgt gattcaattc
    38221 aataccttca aaaatgtcgt gacgttgaac gtgtcatgat cgttactgac catgccatgg
    38281 tagagcttgg tttccttgat cgtatcatcg aacaactgga ccttcgtcgc aataaggttg
    38341 tttaccaaat ctttgcggat gtagaaccgg atccagatat cacaactgta aaccgtggta
    38401 ctgagattat gcgtgccttc aaaccagata ccatcatcgc actcggtggt gggtctccaa
    38461 tggatgctgc caaagtaatg tggctcttct acgagcaacc agaagtggac ttccgtgacc
    38521 ttgtccaaaa attcatggat atccgtaaac gtgccttcaa gttcccattg cttggtaaga
    38581 agactaaatt catcgcgatt ccaactacat ctggtacagg atctgaagta acaccatttg
    38641 ccgttatctc tgataaagca aacaaccgta aatacccaat cgctgactac tcattgacac
    38701 caactgtggc aatcgtagat cctgctttgg tattgacagt tccaggattt gttgctgctg
    38761 atactggtat ggacgtattg actcacgcga cagaagcata cgtatcacaa atggctagtg
    38821 actacactga tggtttagca cttcaagcca ttaaattggt ctttgaaaat ctcgaaagct
    38881 cagttaagaa tgcagacttc cactcacgtg agaaaatgca taacgcttca acaatcgctg
    38941 gtatggcctt tgccaatgcc ttcctaggta tttctcactc aatggcccat aagattggtg
    39001 cgcaattcca cacaatccac ggtcgtacaa atgctatctt gcttccatac gttatccgtt
    39061 acaacggtac acgtccagct aagacagcaa catggcctaa gtacaactac taccgtgcag
    39121 atgaaaaata ccaagatatc gcacgcatgc ttggacttcc agcttctact ccagaagaag
    39181 gggttgaatc ttacgcaaaa gctgtctacg aactcggtga acgtattggg atccaaatga
    39241 attttagaga ccaaggaatt gacgaaaaag aatggaaaga acattctcgt gaattagcct
    39301 tcctggctta tgaagaccaa tgttcaccag ctaacccacg tcttccaatg gtagaccata
    39361 tgcaagaaat catcgaagat gcatactatg gctacaaaga aagaccagga cgccgtaaat
    39421 aattgtttat cagtctagaa gcaagacaaa aactcaattt gagggaaaga tccagtaatt
    39481 tttctatgat aaaaggcatc ctatcaaggt ttttgaacac ctgataggat gcctttttat
    39541 gatattgagg cctttttgcc ctttttgaaa aactagaata gaaacaaaat atataataga
    39601 ttgaaactag agtagtacac atctgcttct aaaacattgt tagaattcga tttgcctgtc
    39661 ctgatcaatt tgtcctgttc ttatttcatt ttaatatata aaaaatat
//
LOCUS       DBJKQU010000012        38261 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.012, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000012 DBJKQU010000000
VERSION     DBJKQU010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 38261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38261
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.012"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            2..74
                     /locus_tag="ACSUUC_000738"
     tRNA            2..74
                     /locus_tag="ACSUUC_000738"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            99..171
                     /locus_tag="ACSUUC_000739"
     tRNA            99..171
                     /locus_tag="ACSUUC_000739"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:132..134,aa:Lys,seq:ttt)
     gene            177..258
                     /locus_tag="ACSUUC_000740"
     tRNA            177..258
                     /locus_tag="ACSUUC_000740"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Leu,seq:tag)
     gene            277..349
                     /locus_tag="ACSUUC_000741"
     tRNA            277..349
                     /locus_tag="ACSUUC_000741"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Thr,seq:tgt)
     gene            372..443
                     /locus_tag="ACSUUC_000742"
     tRNA            372..443
                     /locus_tag="ACSUUC_000742"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:404..406,aa:Gly,seq:gcc)
     gene            451..536
                     /locus_tag="ACSUUC_000743"
     tRNA            451..536
                     /locus_tag="ACSUUC_000743"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:485..487,aa:Leu,seq:taa)
     gene            546..619
                     /locus_tag="ACSUUC_000744"
     tRNA            546..619
                     /locus_tag="ACSUUC_000744"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Arg,seq:acg)
     gene            635..708
                     /locus_tag="ACSUUC_000745"
     tRNA            635..708
                     /locus_tag="ACSUUC_000745"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:669..671,aa:Pro,seq:tgg)
     gene            714..787
                     /locus_tag="ACSUUC_000746"
     tRNA            714..787
                     /locus_tag="ACSUUC_000746"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:748..750,aa:Met,seq:cat)
     gene            801..874
                     /locus_tag="ACSUUC_000747"
     tRNA            801..874
                     /locus_tag="ACSUUC_000747"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Ile,seq:cat)
     gene            885..974
                     /locus_tag="ACSUUC_000748"
     tRNA            885..974
                     /locus_tag="ACSUUC_000748"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Ser,seq:tga)
     gene            988..1061
                     /locus_tag="ACSUUC_000749"
     tRNA            988..1061
                     /locus_tag="ACSUUC_000749"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1022..1024,aa:Met,seq:cat)
     gene            1065..1137
                     /locus_tag="ACSUUC_000750"
     tRNA            1065..1137
                     /locus_tag="ACSUUC_000750"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1098..1100,aa:Phe,seq:gaa)
     gene            1157..1227
                     /locus_tag="ACSUUC_000751"
     tRNA            1157..1227
                     /locus_tag="ACSUUC_000751"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1189..1191,aa:Gly,seq:tcc)
     gene            1263..1336
                     /locus_tag="ACSUUC_000752"
     tRNA            1263..1336
                     /locus_tag="ACSUUC_000752"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Ile,seq:gat)
     gene            1343..1430
                     /locus_tag="ACSUUC_000753"
     tRNA            1343..1430
                     /locus_tag="ACSUUC_000753"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1377..1379,aa:Ser,seq:gct)
     gene            complement(1556..2491)
                     /gene="birA"
                     /locus_tag="ACSUUC_000754"
     CDS             complement(1556..2491)
                     /gene="birA"
                     /locus_tag="ACSUUC_000754"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HHQ8054005.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLIQCDNGKEIWLNSGEISLNSWK"
     gene            complement(2488..3348)
                     /locus_tag="ACSUUC_000755"
     CDS             complement(2488..3348)
                     /locus_tag="ACSUUC_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHQ8054006.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHMGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            3456..5618
                     /locus_tag="ACSUUC_000756"
     CDS             3456..5618
                     /locus_tag="ACSUUC_000756"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0004557 - alpha-galactosidase activity
                     [Evidence IEA];
                     GO_process: GO:0016052 - carbohydrate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HHQ8054007.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQIEKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRRHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYENQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRRL"
     gene            5653..6911
                     /locus_tag="ACSUUC_000757"
                     /pseudo
     CDS             5653..6911
                     /locus_tag="ACSUUC_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            6925..7791
                     /locus_tag="ACSUUC_000758"
     CDS             6925..7791
                     /locus_tag="ACSUUC_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHQ8054008.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIVMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7805..8638
                     /locus_tag="ACSUUC_000759"
     CDS             7805..8638
                     /locus_tag="ACSUUC_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHQ8054009.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            8949..10391
                     /gene="gtfA"
                     /locus_tag="ACSUUC_000760"
     CDS             8949..10391
                     /gene="gtfA"
                     /locus_tag="ACSUUC_000760"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HHQ8054010.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            10529..11722
                     /locus_tag="ACSUUC_000761"
     CDS             10529..11722
                     /locus_tag="ACSUUC_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008754 - O-antigen ligase activity
                     [Evidence IEA];
                     GO_function: GO:0008755 - O antigen polymerase activity
                     [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HHQ8054011.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            12408..14387
                     /locus_tag="ACSUUC_000762"
     CDS             12408..14387
                     /locus_tag="ACSUUC_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HHQ8054012.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            14454..15950
                     /locus_tag="ACSUUC_000763"
     CDS             14454..15950
                     /locus_tag="ACSUUC_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8054013.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15950..16876
                     /gene="oppC"
                     /locus_tag="ACSUUC_000764"
     CDS             15950..16876
                     /gene="oppC"
                     /locus_tag="ACSUUC_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HHQ8054014.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16885..17952
                     /locus_tag="ACSUUC_000765"
     CDS             16885..17952
                     /locus_tag="ACSUUC_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054015.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYAPCHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17963..18889
                     /locus_tag="ACSUUC_000766"
     CDS             17963..18889
                     /locus_tag="ACSUUC_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHQ8054016.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            19508..20317
                     /locus_tag="ACSUUC_000767"
                     /pseudo
     CDS             19508..20317
                     /locus_tag="ACSUUC_000767"
                     /inference="COORDINATES: protein motif:HMM:NF016292.6"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            20329..21206
                     /locus_tag="ACSUUC_000768"
                     /pseudo
     CDS             20329..21206
                     /locus_tag="ACSUUC_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            21219..22022
                     /locus_tag="ACSUUC_000769"
     CDS             21219..22022
                     /locus_tag="ACSUUC_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054017.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(22055..22765)
                     /gene="treR"
                     /locus_tag="ACSUUC_000770"
     CDS             complement(22055..22765)
                     /gene="treR"
                     /locus_tag="ACSUUC_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HHQ8054018.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYIVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            22950..24917
                     /gene="treP"
                     /locus_tag="ACSUUC_000771"
     CDS             22950..24917
                     /gene="treP"
                     /locus_tag="ACSUUC_000771"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HHQ8054019.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLRDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEATKSAAKSNQNVV
                     QGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQVQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            25095..26720
                     /gene="treC"
                     /locus_tag="ACSUUC_000772"
     CDS             25095..26720
                     /gene="treC"
                     /locus_tag="ACSUUC_000772"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HHQ8054020.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            26976..27224
                     /locus_tag="ACSUUC_000773"
     CDS             26976..27224
                     /locus_tag="ACSUUC_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HHQ8054021.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            27431..28225
                     /gene="racE"
                     /locus_tag="ACSUUC_000774"
     CDS             27431..28225
                     /gene="racE"
                     /locus_tag="ACSUUC_000774"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HHQ8054022.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            28222..29193
                     /locus_tag="ACSUUC_000775"
     CDS             28222..29193
                     /locus_tag="ACSUUC_000775"
                     /inference="COORDINATES: protein motif:HMM:NF002698.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HHQ8054023.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            29169..29690
                     /locus_tag="ACSUUC_000776"
     CDS             29169..29690
                     /locus_tag="ACSUUC_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HHQ8054024.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            29687..30148
                     /gene="cbpB"
                     /locus_tag="ACSUUC_000777"
     CDS             29687..30148
                     /gene="cbpB"
                     /locus_tag="ACSUUC_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HHQ8054025.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            30145..30879
                     /gene="xerD"
                     /locus_tag="ACSUUC_000778"
     CDS             30145..30879
                     /gene="xerD"
                     /locus_tag="ACSUUC_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HHQ8054026.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            30879..31607
                     /locus_tag="ACSUUC_000779"
     CDS             30879..31607
                     /locus_tag="ACSUUC_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HHQ8054027.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            31626..32195
                     /gene="scpB"
                     /locus_tag="ACSUUC_000780"
     CDS             31626..32195
                     /gene="scpB"
                     /locus_tag="ACSUUC_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HHQ8054028.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            32182..32903
                     /locus_tag="ACSUUC_000781"
                     /pseudo
     CDS             32182..32903
                     /locus_tag="ACSUUC_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
     gene            32903..33145
                     /gene="yidD"
                     /locus_tag="ACSUUC_000782"
     CDS             32903..33145
                     /gene="yidD"
                     /locus_tag="ACSUUC_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HHQ8054029.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(33370..34335)
                     /locus_tag="ACSUUC_000783"
     CDS             complement(33370..34335)
                     /locus_tag="ACSUUC_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HHQ8054030.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIIGMPTKTIPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSIKANIES
                     LASAFGETSIQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(34431..35183)
                     /locus_tag="ACSUUC_000784"
     CDS             complement(34431..35183)
                     /locus_tag="ACSUUC_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054031.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(35180..36136)
                     /locus_tag="ACSUUC_000785"
     CDS             complement(35180..36136)
                     /locus_tag="ACSUUC_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HHQ8054032.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSFFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(36126..37085)
                     /locus_tag="ACSUUC_000786"
     CDS             complement(36126..37085)
                     /locus_tag="ACSUUC_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8054033.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(37382..37492)
                     /locus_tag="ACSUUC_000787"
     CDS             complement(37382..37492)
                     /locus_tag="ACSUUC_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HHQ8054034.1"
                     /translation="MNYLFQEDSSSQIFNLETKKGYTIKEIFKTAEELLN"
     gene            complement(37508..38209)
                     /locus_tag="ACSUUC_000788"
     CDS             complement(37508..38209)
                     /locus_tag="ACSUUC_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HHQ8054035.1"
                     /translation="MTKTILVTGETGYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKSYLEENQIDAALHCAGETVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNAAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
BASE COUNT        10968 a         7189 c         8564 g        11540 t
ORIGIN      
        1 aggtcccgta gtgtagcggt tatcacgtcg ccctgtcacg gcgaagatcg cgggttcgat
       61 tcccgtcggg accgtttaag gtaacgcaag ttattttaga ctcgttagct cagttggtag
      121 agcaattgac ttttaatcaa tgggtcactg gttcgagccc agtacgggtc atatatgcgg
      181 gtttggcgga attggcagac gcaccagatt taggatctgg cgcttaacgg cgtgggggtt
      241 caagtccctt aacccgcatt aagatataac aaatgagccg gcttagctca gttggtagag
      301 catctgattt gtaatcagag ggtcgcgtgt tcaagtcatg tagccggcat ttttagatag
      361 aagaaaacag tgcgaacgta gttcagtggt agaacaccac cttgccaagg tgggggtcgc
      421 gggttcgaat cccgtcgttc gcttagagag gccggggtgg cggaactggc agacgcacag
      481 gacttaaaat cctgcgattg gtaacgatcg taccggttcg attccggtcc tcggcataat
      541 atggagcacc cttagctcaa ctggatagag tacctgacta cgaatcaggc ggttagaggt
      601 tcgactcctc tagggtgcat ttttctattt aactcgggaa gtagctcagc ttggtagagt
      661 acttggtttg ggaccaaggt gtcgcaggtt cgaatcctgt cttcccgatt catggcggtg
      721 tagctcagct ggctagagcg tccggttcat acccgggagg tcgggggttc gatccccttc
      781 gccgctataa tgatcttgtc ggacctttag ctcagctggt tagagctctc ggctcataac
      841 cgagtggtcg taggttcaag tcctacaagg tccatttgaa tattggagga ttacccaagt
      901 ccggctgaag ggaacggtct tgaaaaccgt caggcgtgta aaagcgtgcg tgggttcgaa
      961 tcccacatcc tccttttata ttattaacgc gggatggagc agctcggtag ctcgtcgggc
     1021 tcataacccg aaggtcgtag gttcaaatcc tgctcccgca ataaggctcg gtagctcagt
     1081 tggtagagca atggattgaa gctccatgtg tcggcggttc gattccgtct cgcgccattt
     1141 tattgatagt atttatgcgg gtgtagttta gtggtaaaac tacagccttc caagctgttg
     1201 tcgcgagttc gattctcgtc acccgctttg aactttgttc aaattaccaa gttttttaac
     1261 ttgggcgcgt agctcaggtg gttagagcgc acgcctgata agcgtgaggt cggtggttcg
     1321 agtccactcg tgcccattaa ttggagaatt actcaagagg ctgaagagga cggtttgcta
     1381 aatcgttagg tcgggtaact ggcgcaaggg ttcgaatccc ttattctccg ttttaatgag
     1441 agtttgtaac tctctttttt gtttttagag acaataaaac ttcagatccg taaaacttaa
     1501 ttgaattact aatctgaagt tatttttata tcgtttatat tataattgtg ttattttact
     1561 tccaactatt gagagaaatt tcgccactat ttagccagat ttcttttccg ttatcacatt
     1621 gaattaaaag ttttccattt tctgagatgt ctttagcaag tcccttgtag tctttttgct
     1681 ctagtgtgaa agtgacttct tttcctagaa tgaatgactg ttttttgtat aggtataata
     1741 gctcttctgc tggtgtttcg aagaaagcac gccagatttc tatgatcaat tcattccttg
     1801 ttataggagc tgtagcttta aataagctgg cagctttttc ttttaattcc tgagggaagt
     1861 ctttaatagt gaaattgata cctactccaa taatgatatc tgtgactaag ccagtttcta
     1921 cagaggtcat tgcttcagta aggattcctc caattttatg attgtttaga tagatatcat
     1981 tgacccattt tatgtcgaca tctattaaag ttaggttctt aatagctttg tagacagctc
     2041 cagctacaag tagtgtgtag gatggtaatt tgtcataggg gagatttggt ttaagatgga
     2101 gtgtcatata aataccacct tgtggtgagt agaaggaacg ttgaaaacgg cctcggcctg
     2161 ctgtttgata ggaagctaga tagagggtat ttgcttcatg gcctaaatca attgcttctt
     2221 ttgcatctag ttgtgttgat tttgtttcgg gtttaaagct gactttaatt ggaagatttt
     2281 cttctagaat ctctggaaga ataaggtcac cattcatcaa tttatatcct ctatttttga
     2341 tactatcaat ttcaatgcct tcttgttcta gtcgcttgat ggctttccaa attgatgttc
     2401 ggcttaggga tagtttttct gcgatttttt ctccgctgat atagtcggtt tctttagata
     2461 ggatttggta gacagcttgg taggatttca taatgttgcc tttctcacta gttggtattg
     2521 agagtattct tttcttgtat gacttggagt ctgattaaag tattgtttat aagctttcga
     2581 aaaatggagt ggatctgaaa aacctaccga gtatgcaatt accttgatgg actcttgggt
     2641 attttcgaga agttgtctag ctcggtgcat tcgaacgtag agtaggtatt ctttgggtga
     2701 taaggtatta aattctttga atacgcttga taagtagctt ctgtgaacgg atagttcttt
     2761 tgctaaatct tgaattgtaa gtgattgagg atagtggcta tcaattaatc gtttgcattc
     2821 aagatagagt tggtgggttg atgaaatatt cttttttttc tgattgggag caatagttcc
     2881 catatgaaac atcagttcat gaagttgtcc catgatatgg agttgagcta attcacttga
     2941 ttttgtaatc tgagcgaagc ggacaatgtc tgagatgagt tttgcagtag tctgggtatg
     3001 acaagtttca gattggatga gataggattg atcagaaatt tgggaaagag caaaataatc
     3061 aggggatttc cctccagtga ttcctaacca gtagtaggcc caaggttctt tactatctgc
     3121 ttgataaaag gttagttcct ctggttttaa tagaaagaaa tctccttctt ttaaatcaac
     3181 aattttaccc ttgtaataaa attttccttg tcctttagta atgtaatgta gaacgtatgt
     3241 atcacgaatg gctggaccaa aagagtaatt aggtgtgcat tcctcatatc cataaaagct
     3301 tagggcaagg tcgattgttc cagtctggta ttctgaaaaa actaacatgt gctacctcct
     3361 acctaacatt ttaccatatt cttgagacat ttttctattt tggaaagcga tttcaggtga
     3421 taaaatataa tcaataaagt gatgaggtga agtaaatggg agttaggata gagaataatc
     3481 tattttatgt tgagagtaaa aatctaagtt tgattattga aaatcgaaat ggctacttac
     3541 ttttgaaaca tttaggaaag actattaaga actataaagg ttccaatagt gtttatgaac
     3601 gagaccatgc cttttcagga aatccaacgg ctactaatcg aacctttagt ttagatactc
     3661 agcgacagat ttttggacaa catggcttag gagattttag gaaaccaacc atacaggttc
     3721 agcatagtgt aactgaagta acagactttc gatttgtaga agcaaagatt ttaaaaggtc
     3781 agaatggtcc acagggctta ccttctccac atagcatgga cgatacagag actcttgtct
     3841 taatgttaga agattctaag gctcaactta gtctgacttt gtattatact acttttaata
     3901 atgatgcgac tattgctagc tacagtaaat tagataataa tagtaatcag gaagttgtca
     3961 tccataaaga tttttctttt atggctgatt ttccagctgc agattacgaa atagtaactc
     4021 tgcagggtgc ttatgctcgt gaaaagactg ttagacgtca acaggtagaa caaggaatct
     4081 tttcgattag ctcaaaccga ggtgcttctg gtcatgctca aacaccagct cttctactat
     4141 gcgaacaagg agtcacagag gatgctggga atgtgtttgc tattcaacta atgtatagtg
     4201 gcaactttga agcttttgtt caaaaaaatc aattgaatga agttcgggtg gctattggca
     4261 ttaatccaga aaacttttct tggaagttag ctcctgagga atactttgaa acaccggtag
     4321 ctttagtgac ccattcagat cagggattaa ctggtattag tcatgaaagt cagaattttg
     4381 tactgaagca cattatgcta agtgaatttt ctaaaaaaga acgtccaatt ctaatcaata
     4441 actgggaagc tacttacttt gactttcaga tagaaaaact gttagagtta gcagatgaag
     4501 ctaagaaagt tggcattgaa ctttttgtat tagatgatgg ttggtttggc aatcgttttg
     4561 atgataatcg tgctttaggt gattgggttg ttaatgagga aaaactgggt ggaagtctag
     4621 aaagtctgat ttcagctatc catgaaagag gtttgcagtt tggactttgg ttagaacccg
     4681 aaatgatttc tgtagatagt gatttgtatc gtcgacatcc tgactgggct attcaggttc
     4741 ctgactatga gcatacttat tctcggaatc aattagtact taatcttgcc aatcctcagg
     4801 tagtagaata cttgaaaagt gtcttagatc aactcctatc ttatcatgat attgattaca
     4861 ttaaatggga tatgaaccgc aatatcacta agctagggaa tggattaact tatctagaga
     4921 cacagatgca atctcatcag tacatgctgg ggctttacga actcgtttct tatctgacag
     4981 agaagcacag ccatattctc tttgagtcct gctctggtgg tggtggacga aatgatcttg
     5041 gtatgatgcg ctatttccca caagtttggg ctagtgataa tactgatgcc attgcacgtt
     5101 taccaattca atacggttca tcctatctct atccaaccat ttctatgggg gctcatgtgt
     5161 cagcagtacc gaatcatcag atgggacgaa tgacaccatt agaaacacgt ggccttgtag
     5221 caatgatggg aaatttgggc tatgaacttg atttgacaaa tttatcagat gaagagaaag
     5281 ctacgattgc taatcaggtg aacttgtata aagaattacg accagtagtt cagttaggac
     5341 agcagtatag actaattaat cctgatactg tatccaatga agcagctgta caatttaatt
     5401 acgaaaatca aacgattgta acctacgttc gcgttttatc tgttgtagag accatggaaa
     5461 caactttaaa attaaaagat ttggatgaag agggactata taaattacag gaaaatggcg
     5521 aagtttactc aggtgcagaa ctaatgtatg cgggcctaac tgttatctta tcccaaggag
     5581 attttttgag tagacagtat atttttagaa gactatgata agggtgtata aatttataaa
     5641 ggaggctttc taatggaatg gtataaaaaa atcggacttc ttgcaactac aggtttagct
     5701 ttggttgggc tcggcgcttg ctccaactat ggtaaatctg cggatggcac agtgaccatc
     5761 gagtatttca accagaaaaa agaaatgacc aaaaccttct caaaatcact cgtgattttg
     5821 agaaggaaaa ccctaagatc aaggtcaaag tcgtcaatgt accaaatgct ggtgaagtat
     5881 tgaagacacg cgttctcgca ggagatgtgc ctgatgtggt caatatttac ccacagtcca
     5941 tcgaactgca agaatgggca aaagcaggtg tctttgaaga tttgagcaac aaagactacc
     6001 tgaaacgcgt gaaaaatggc tacgctgaaa aatatgctgt aaacgaaaaa gtttacaacg
     6061 ttccttttac agctaatgct tatggaattt actacaacaa agataaattc gaagaactgg
     6121 gcttgaaggt tcctgaaacc tgggatgaat ttgaacagtt agtcaaagat atcgttgcta
     6181 aaggacaaac accatttgga attgcaggtg cagatgcttg gacactcaat ggttacaatc
     6241 aattagcctt tgcgacagca acaggtggag gaaaagaagc aaatcaatac cttcgttatt
     6301 ctcaaccaaa tgccattaaa ttgtcggatc cgattatgaa agatgatatc aaggtcatgg
     6361 acatccttcg catcaatggc tctaagcaaa agaactggga aggtgctggc tataccgatg
     6421 ttatcggagc cttcgcacgt ggggatgtcc tcatgacacc aaatgggtct tgggcgatca
     6481 cagcgattaa tgaacaaaaa ccgaacttta agattgggac cttcatgatt ccaggaaaag
     6541 aaaaaggaca aagcttaacc gttggtgcgg gagacttggc atggtctatc tcagccacca
     6601 ccaaacatcc aaaagaagcc aatgcctttg tggaatatat gacccgtcca gaagtcatgc
     6661 aaaaatacta cgatgtggac ggatctccaa cagcgatcga aggggtcaaa caagcaggag
     6721 aagattcacc gcttgctggt atgaccgaat atgcctttac ggatcgtcac ttggtctggt
     6781 tgcaacaata ctggaccagt gaagcagact tccatacctt gaccatgaac tatgtcttga
     6841 ccggtgataa acaaggcatg gtcaatgatt tgaatgcctt ctttaacccg atgaaagcgg
     6901 atgtggatta ggagtagaga gactatgaaa aaagtattac aaaaatattg ggcatgggct
     6961 tttgtggtca tccccctctt gttacaagca attttcttct atgtgccgat gtttcaagga
     7021 gccttttaca gttttaccaa ctggacagga ttgacttaca actacaaatt tgtcggctta
     7081 aacaacttta agctcctctt catggatcca aaattcatga atgcgattgg ctttaccgca
     7141 atcattacga ttgtcatggt ggttggtgag attgcactcg ggatcttcat tgcgcgtgtc
     7201 ttgaactcta aaatcaaagg ccaaaccttc ttccgtgctt ggttcttctt cccagctgtt
     7261 ttatctggtt tgacagtggc tttgatcttc aagcaagtct tcaactacgg tcttccagcg
     7321 attgggaatg cccttcatat tgaatttctc caaaccagtc ttttagggac taagtgggga
     7381 gcaatctttg cggctgtctt tgtccttctt tggcaagggg tggctatgcc catcatcatc
     7441 ttcctagctg gtttgcaatc tattccaact gagattacag aggcagcaag gattgatggt
     7501 gcgactagca agcaagtttt ctggaacatt gaattgcctt acttgctacc aagtgtctct
     7561 atagtcttta tcctagccct aaaaggtggg ctgactgcct ttgaccaagt ctttgccatg
     7621 accggtggtg gtccaaacaa tgccacaacc tcacttgggc tcttggttta taactatgcc
     7681 tttaaaaaca accaattcgg ttatgccaat gccattgccg taatcttgtt cttcttaatt
     7741 gtagtgattt cgatcatcca attgagagta tctaagaaat ttgaaattta agaggagaag
     7801 catgatgaaa caagatgaaa gaaaagccct gattggcaaa tacattctat tgattctagg
     7861 atcggttctg attttagtgc cgctccttgc taccctcttt agttccttca aacccactaa
     7921 ggatattgta gataatttct ttggctttcc aaccaacttc acatgggaca actttagccg
     7981 tctcttagct gatgggattg gaggctatta ttggaactct gtcgtcatca ctgtcttatc
     8041 tttacttgca gtaatgatct ttatacctat ggcagcctac tccatcgctc gcaatatgag
     8101 taaaagaaaa gcctttacca tcatgtatac cctcttaatc ctcggaatct tcgtaccttt
     8161 ccaagtcatc atgattccga ttacggttat gatgagtaaa ctcggtttgg ctaatacctt
     8221 tggtttgatc ttactctact tgacctatgc gattccacag accctctttc tctatgttgg
     8281 ctatatcaaa atctcgattc cagaaagtct ggatgaagca gcagagatcg atggggctaa
     8341 tcaatttaca acctatttcc gcatcatctt cccaatgatg aaaccgatgc atgcgacaac
     8401 catgatcatc aatgcccttt ggttctggaa tgacttcatg ttgccactcc ttgtcttgaa
     8461 ccgggattcc aaaatgtgga ctctgccttt gttccaatac aactacgcag gccaatattt
     8521 caacgactac ggaccaagct ttgcctctta cgtggtcggc attatcagta tcaccattgt
     8581 ctatctcttc ttccaacgcc atatcatttc aggaatgagc aacggggcag tgaagtaata
     8641 ctcaatgaaa atcaaagagc aaactaggaa gctagccgca ggctgtactt gagtacggta
     8701 aggtgaagct gacgtggttt gaagagattt tcgaatagta taagaagagc tcatggaatc
     8761 tatagtcttt gacacagagg aagagttcag cttgttgata attctatgta gaaaacaaga
     8821 aagtagtact ttgtttatca cagtctatat tagtacgagt ttgatgataa atagagattt
     8881 aaaatgaatt ttatttatga agccagatca tatgatactt ggcttcaatt agaaaaagga
     8941 gagtaatgat gccaattcaa aataaaacca tgttgattac ctattctgat agccttggaa
     9001 ataatcttaa agacttatat gataatttgg aagagcattt tggagatgct attggaggag
     9061 ttcacctttt accatttttc ccatcaacag gtgatcgtgg atttgcgcca gttgactacg
     9121 acgaagtgga ctcagctttt ggtgattggg aggatgttaa gcgtttaggt gagagatatt
     9181 atcttatgtt tgattttatg attaatcata tttctcgtca atccaagtat tataaggact
     9241 atcaagaaaa acatgaagcc agtgaattta aagctctctt tttaaactgg gataagtttt
     9301 ggccagaaaa ccgtccgaca cagtctgatg tagatttaat ttacaagcgt aaggatcgtg
     9361 caccaaagca agagattgtg tttgaagatg gttcagtgga acatttgtgg aatacctttg
     9421 gtgaggagca gattgatctt gatgtgacca aagaagtaac tatggaattt atccgtaaga
     9481 ccattcagca cttggcaagt aatgggtgtg atttgattcg tctagatgcc tttgcttatg
     9541 cagtgaagaa attggatact aatgatttct ttgtggaacc agatatttgg gatttattgg
     9601 acaaagttcg agatatcgct gctgagtatg ggacagagct tttacctgag attcatgaac
     9661 actattcgat tcagtttaaa atagcagacc atgattacta tgtttatgat tttgctcttc
     9721 caatggtgac actttatact ctttacagtt ccagaacaga gcgtttggct aagtggttaa
     9781 agatgagccc gatgaagcaa tttacgacgc tagataccca tgatgggatt ggagtagtag
     9841 atgtcaagga tatcctgacc gatgaggaga ttgactatgc ttcaaatgaa ctctataagg
     9901 ttggagccaa tgtcaaacgt aagtactcta gtgccgagta taacaactta gatatctacc
     9961 aaatcaattc aacctactat tcagcgcttg gagatgatga tgtcaagtat tttctcgctc
    10021 gtctaattca agcttttgcc ccaggtattc ctcaggttta ctatgtgggt ctattagcag
    10081 gcaagaatga cttgaaatta ttagaagaaa ctaaagaagg tcgaaatatt aatcgtcatt
    10141 actatagcaa cgaggaaata gcaaaagaag tgcaacgacc tgttgtgaag gcccttctca
    10201 atctattttc tttccgtaac cgttcagaag cctttgatct agaagggact actgagatag
    10261 agacaccaac agctcacagc attgtaatca aacgtcaaaa taaagataag tccgtaacag
    10321 cagtagtaga aattgatttg caaaatcaga cttatcgggt aattgagaat ggagttgaag
    10381 tatcattttg aagccttgat atggtggata aaatagggtt tttattttgg aaaacgtttc
    10441 ctttgttttc aaattgctaa aaaagtggta caatatagga tagcttacta ttatctgaat
    10501 cagctgattt ggagagaaag gattcatttt gaaatcaata ggctttattg aaaagctgaa
    10561 ggggttgtct agtaaagagc tgattttatt gggaattatc ctaagtatct ttttaccctt
    10621 ttatcttttt gtagttgtac tctgtttata tattatcagt ttgattttta caggagacat
    10681 gaaaagtatt cttcagaaaa tgggggagca tccgatgctg cttctttttc ttagctatag
    10741 tactgttata tccattcttg cacaaaattg gatgggtctt gtggcttcag taggaatgtt
    10801 tctatttact attttctttt tgcactatca gtcgatttta tcccataaat tctttcgatt
    10861 gattttgcag ttcgtcttgt ttggtagtgt cttgtcagct gcttttgcca gtttagaaca
    10921 tttccaaatt gtgaagaaat ttaactatgc ttttctttca cccaatatgc aggtgtggca
    10981 tcagaaccgg gcagaagtga ccttctttaa tcctaattat tatggaatta tttgttgttt
    11041 ctgtattatg attgctttct atctgtttac aacgaccaag ttgaattggt tgaaagtatt
    11101 ctgtgtgatt gcaggctttg ttaatctctt tggtttgaac tttactcaaa atcgaactgc
    11161 ctttcctgct attatcgctg gagcaattat ctatctcttt acgactatta aaaactggaa
    11221 ggccttttgg cttagtattg gggtcttcgc gattggtttg agtttcctct tttctagtga
    11281 tttgggagtt cgaatgggta ctttagactc ttctatggaa gaacgcattt ctatctggga
    11341 tgctgggatg gccttgttta agcaaaatcc tttttggggt gaagggccat tgacctatat
    11401 gcactcttat cctcggatac atgctcctta tcatgaacat gcccacagtc tttatattga
    11461 tacgattctg agttacggaa ttgtgggtac cattttatta gttttgtctt ctgttgctcc
    11521 tgttcgcttg atgatggata tgagtcagga gtcggggaaa cgtccgatta tcggccttta
    11581 tctatctttc cttacagtgg ttgctgtgca cggaattttt gacttggctc tcttctggat
    11641 tcagtcaggc tttattttct tgctagttat gtgcagtatt ccattggagc atcgaatgtt
    11701 ggtatcggac atgacggatt aagttttata agtttgaaat cttctacctt gggtaggaga
    11761 tttttttata ctatgggcat gtcgtgcatc tgaggtgtaa gtcctctgta gggatccact
    11821 accggtgaat acaatagcgc tccccaagcc tgactgtcgt gaggtagcgg attaaaatgg
    11881 tctggggata gatcgtttta agtctgacgc aggaaataag aattgtcaga gaaagcaata
    11941 gtgaaatcgt aggctatgaa tagaaacgtg atagcgagga gcatatagtg gataaggtag
    12001 cgagaaattt taaagtataa aagatagtct taatctatat atgtaaatca caaaagtaat
    12061 tgaattcgga ataaggttgg tgtgaaaaga catagtaaac tgaatcttga atactagaat
    12121 gatacttcta caatattgtt ataatttaat ttgaattcca aaatcacatt gttccgtccg
    12181 tatttcattt tactgtatgt cttcctaaac tccaaagttt ctgcgtcaaa tttcctattt
    12241 tcactgtagt ctttgacact tcgaacgaca atttgaatca tatattcaaa aaaaatgaaa
    12301 aatttgtgcc aacaagccta aatattctga aaatttgttt gatttttaat ggataatgtg
    12361 atataatggt tgtcaatcta taattcacat aaacagagga gtagaaaatg aaaaaaaatc
    12421 gtgtatttgc tacagcaggt cttgttttat tagcagcagg tgtacttgca gcatgcagtt
    12481 cttcaaaatc atctgattca tcagccccta aagcttatgg ctatgtttat acagcagacc
    12541 cagaaacctt ggactacctg atttcaagta aaaatagtac aacagtagtg acttcaaatg
    12601 ggattgatgg tttattcact aacgataatt acggtaatct tgctcctgca gttgcagagg
    12661 attgggaagt ctctaaggat ggtttgacct acacttataa gattcgtaaa ggggttaaat
    12721 ggtttacctc tgatggagaa gaatatgcag aggtgacggc taaagatttc gtgaacggtt
    12781 taaaacacgc agcagataaa aaatcagaag ctatgtattt agctgaaaat tcggttaaag
    12841 gcttggcaga ttatctatca ggaacttcaa cagatttttc aacagttggt gtcaaggcgg
    12901 ttgatgatta tacgttacaa tacactttga accagcctga accgttctgg aactctaagt
    12961 tgacctattc tattttctgg cctctgaatg aagaattcga aacatcaaaa ggaagcgatt
    13021 ttgctaaacc aacagatccg acatccttgc tttataatgg tccattcttg ttgaaagggt
    13081 tgactgcaaa atcttctgta gagtttgtaa aaaatgagca atattgggat aaagaaaatg
    13141 tccacctaga tactatcaat ctagcttact atgatggatc agatcaggag tcgctagagc
    13201 gtaacttcac tagtggagct tatagttatg cccgtcttta ccctaccagc tccaactatt
    13261 ctaaggttgc agaagaatac aaggacaata tctattacac acaatcaggc tctgggattg
    13321 ctggtctggg tgtgaatatt gatcgccaaa gttacaacta tacttctaaa actacagatt
    13381 cagagaaagt agctactaag aaggcattgc ttaacaaaga tttccgtcaa gccttgaatt
    13441 ttgctcttga tcgctcagct tactcagctc aaatcaatgg taaagatgga gcagctttag
    13501 cagttcgtaa tttatttgta aaaccagact ttgtttcagc tggtgagaag acctttggtg
    13561 atttagtcgc tgctcaactt cctgcttatg gtgatgagtg gaaaggtgtg aatttagctg
    13621 atgggcagga tggtttattc aatgctgaca aggccaaggc agagtttgcg aaagctaaga
    13681 aagctttaga agcagacggc gttcagtttc ctattcatct ggacgttcca gtagaccaag
    13741 catcaaaaaa ctacatatct cgtattcagt cctttaaaca atctgtagaa acagttcttg
    13801 gtgttgaaaa tgtcgttgtt gatattcaac aaatgacaag tgatgaattc cttaatatta
    13861 cttactatgc tgccaatgct tcatctgagg attgggatgt atcaggagga gtttcatggg
    13921 gtccagacta tcaagaccca tctacttacc tggatatttt aaaaacaact agcagtgaaa
    13981 ctacaaaaac atatttagga tttgataatc caaatagccc ttcagtagtt caagttggtt
    14041 tgaaagaata cgataaatta gttgatgaag ctgccagaga gacaagcgac ttgaatgtcc
    14101 gttatgaaaa atatgcagcg gctcaagcat ggttgacaga tagttcactc tttattcctg
    14161 ctatggcttc ttctggtgca gcaccagtgc tttcacgaat tgttccattt actggagctt
    14221 ctgcgcaaac aggctctaag gggtcagatg tttacttcaa atatttgaaa ttacaagata
    14281 aagtggtgac taaggaagag tatgaaaaag ctcgtgaaaa atggttgaaa gaaaaagctg
    14341 aatcaaatga gaaagctcaa aaagaattgg caagtcatgt gaagtaaata atttctaata
    14401 gaactttctc tccatgagga gaaggttctt ttgggatttt taaaggaaat aatatgaaaa
    14461 aatatatttt tatgcgtgtt ttgcggtcat tggtttcgat tttcttagta acgactttga
    14521 cctacacgat tatctatacc ttggttcctc gaaaattgat tttcaagcag gatcctaact
    14581 ataataaaat tgcgacaacg gctgataaac gtgataacta tgaaaatact gtgtttgagc
    14641 gtatgggcta cattgagtat tacgatacta aagagttgca agaaaaggca agtagcatgg
    14701 attcttctgt aacagtagaa gcaaatgcga ccaataaagc tatttatgaa aagtacatca
    14761 atcaattagg tcatggttgg actttgggag aatttactga aagtggtcaa ttctatgcta
    14821 ctcgtgaaat tccaattttt gaacgtgttt ttcacttcta tgctaacttg attgacattg
    14881 accatacaaa taaaatccaa gaccctgaaa atccagactt gaaacgctac cttcgttttg
    14941 aaaatgatcc agctatcgga tggtcattgg tcggttcagg aactaaacat aaatatctct
    15001 tgtactttaa cagtcagttc ccatttgttc atcaaaactt tgtgaacttg aatttaggtg
    15061 actcttaccc aacctatgct aatacaccag ttcttcaggt tattactcaa ggtcaaggac
    15121 aaaccaaaac tgcccaagtt cagttcccaa caggtaagaa aacgtcttct gtaaatattt
    15181 actcaagaac ctacaagtca cctagtcagg ctgactctcg tgaagtagct agctatggga
    15241 aagatgatcc ttatacagcg actgaaagta attaccaata tccatctatg attgtcagct
    15301 ctgctattac tggtttgatt ggtttggttc ttgcctatgc tcttgccgtg ccacttggtt
    15361 cagccatggc tcgtttcaag aacacttgga ttgatagcct atcaacaggg actttgacct
    15421 tcttgcttgc tcttccaacg attgccttgg tttacatcgt tcgattgatt ggatcatcta
    15481 ttgcccttcc agattcattc cctatcttgg gagctggaga ttggcgttct tacgttttac
    15541 cagcagtcat ccttggtttg ttgggtgctc ctgttacagc catttggatt cgtcgttaca
    15601 tgattgactt gcaatctcaa gactttgttc gtttcgctcg tgcaaaaggt ttgtctgaaa
    15661 aagaaatttc aaacaaacac atctttaaaa atgccatggt tccgctggtt tcaggaattc
    15721 ctggtgccat tattggggtt atcggtggtg caacccttac tgaaacagtc ttcgccttcc
    15781 caggtatggg taaaatgttg attgactctg taaaagcatc taataactct atggtcgttg
    15841 gtcttgtctt catctttaca tgtatttcta tcttctcacg tcttttggga gatatttgga
    15901 tgactattat tgacccacgt attaaattga ctgagaaagg aggcaaataa tgtctacaat
    15961 cgataaagaa aaatttcagt ttgtaaaacg tgacgatttt gcctctgaaa ctattgatgc
    16021 gccagcatat tcttactgga aatcagtgtt taaacaattt atgaagaaaa aatcaactgt
    16081 agtcatgttg ggaatcttgg tagccatcat tttgataagt ttcatctacc caatgttttc
    16141 taagtttgat ttcaatgatg tcagcaaggt aaacgacttt agtgttcgtt atatcaagcc
    16201 aaatgcggag cattggttcg gtactgacag taacggtaaa tcgctctttg acggtgtctg
    16261 gttcggagct cgtaactcca tcctcatttc tgtgattgcg acagtgatta acttggttat
    16321 cggtgttttt gtcggtggta tttggggtat ttcaaaatca gttgaccgtg tcatgatgga
    16381 agtttacaac gtcatctcaa acatcccacc tcttttgatt gttattgtct tgacttactc
    16441 aatcggagct ggattctgga atctgatttt tgccatgagc gtaacaacat ggattggtat
    16501 tgccttcatg atccgtgtgc aaatcttgcg ctatcgtgac ttggaataca acttggcgtc
    16561 acgtactttg ggaacaccaa ccttgaagat tgttgccaaa aatatcatgc ctcaattggt
    16621 atctgttatt gtgacaacca tgactcaaat gcttccaagc tttatctcat acgaagcctt
    16681 cttgtctttc ttcggtcttg gattaccgat tacagtgcca agtttgggtc gtttgatttc
    16741 ggattattca caaaacgtaa caaccaatgc ttacttgttc tggattccat tgacaaccct
    16801 tgtcttggta tccttgtccc ttttcgtagt tggtcaaaac ttagcggatg ctagtgatcc
    16861 acgtacacat agataggagt agaaatgaca aaagaaaaaa atgtaatttt gactgctcgc
    16921 gatattgtcg tggaatttga cgttcgtgac aaagtattga cagccattcg cggcgtttcc
    16981 cttgaactag tcgaaggaga agtattagcc ttggtaggtg agtcaggatc aggtaaatct
    17041 gttttgacaa agaccttcac aggtatgctc gaagaaaatg gtcgcattgc ccaaggtagt
    17101 attgactacc gtggtcagga cttgacagct ttatcttctc acaaggattg ggaacaaatt
    17161 cgtggtgcta agattgcgac tatcttccag gacccaatga ctagtttgga ccccattaaa
    17221 acaattggta gtcagattac agaagttatt gtaaaacacc aaggaaaaac agctaaagaa
    17281 gcgaaagaat tggccattga ctacatgaat aaggttggca ttccagacgc agatagacgt
    17341 tttaatgaat acccattcca atattctgga ggaatgcgtc aacgtatcgt tattgctatt
    17401 gcccttgcct gccgacctga tgtcttgatc tgtgatgagc caacaactgc cttggatgta
    17461 actattcaag ctcagattat tgatttgcta aaatctttac aaaacgagta tcatttcaca
    17521 acaatcttta ttacccacga ccttggtgtg gtggcaagta ttgcggataa ggtagcggtt
    17581 atgtatgcag gggaaatcgt tgagtatgga acggttgagg aagtcttcta tgccccttgc
    17641 catccatata catggagtct cttgtctagc ttgcctcagc ttgctgatga taaaggggat
    17701 ctttactcaa tcccaggaac acctccgtca ctttatactg acctgaaagg ggatgctttt
    17761 gccttgcgtt ctgactacgc aatgcagatt gacttcgaac aaaaagctcc tcaattctca
    17821 gtatcagaga cacattgggc taaaacttgg cttcttcatg aggatgctcc aaaagtagaa
    17881 aaaccagctg tgattgcaaa tctccatgat aagatccgtg aaaaaatggg atttgcccat
    17941 ctggctgact aggaggaagg aaatgtctga aaaattagta gaaatcaaag atttagaaat
    18001 ttccttcggt gaaggaagta agaagtttgt cgcggttaaa aatgctaact tctttatcaa
    18061 caagggagaa actttctcgc ttgtaggtga gtccggtagt gggaaaacaa ctattggtcg
    18121 tgctatcatc ggtctaaatg atacaagtaa tggagatatc atttttgatg gtcaaaagat
    18181 taatggtaag aaatcgcgtg aacaagctgc ggaattgatt cgtcgaatcc agatgatttt
    18241 ccaagaccct gccgcaagtt tgaatgaacg tgcgactgtt gattatatta tttctgaagg
    18301 tctttacaat caccgtttat ttaaggatga agaagaacgt aaagagaaag ttcaaagtat
    18361 tatccgtgaa gtaggtcttc ttgctgagca cttgactcgt taccctcatg aattctcagg
    18421 cggtcaacgt caacgtatcg gtattgcccg tgccttggtc atgcaaccag actttgttat
    18481 tgcagatgag ccaatttcag ccttggacgt ttctgtacgt gcccaagtct tgaacttgct
    18541 caaaaaattc caaaaagagc tcggcttgac ctatctcttc atcgcccatg acttgtcggt
    18601 tgttcgcttt atttcagatc gtatcgcagt tatttacaag ggtgttattg tagaggttgc
    18661 agaaacagaa gaattgttta acaatccaat tcacccatat actcaagcct tgctttcagc
    18721 ggtaccaatc ccagatccaa tcttggaacg taagaaggtc ttgaaggttt acgacccaag
    18781 tcaacacgac tatgagactg ataagccatc tatggtagaa atccgtccag gtcactatgt
    18841 ttgggcgaac caagccgaat tagcacgtta tcaaaaagga ctaaactaat aatggtttta
    18901 taatttccat gtcaattttt atggaaatta taaaactttt tttgttggac tgatttgaaa
    18961 aactttgaaa gcttcctgaa agaattttcg aaaaatttta aaaaattctg aaatattatt
    19021 gacaggtgat gaaaaaggtg gtaggatagg aagcatcaaa aaagaaagca gaaaaagaaa
    19081 tgaataagag acaagccgta actatgaatc aaaactttta ctttagctac tttagatagt
    19141 gtttgtagac atgtcaccat ggatgcaaac agttcaagca atttgtttgt atctatgtgg
    19201 ctaagatttt tgattgtggt ccatatagat gaatatctaa atggactagc taagttgtaa
    19261 cttgttaggt tatttcaagt atccgtttag atagtatcta ggcggttttt tgttttatct
    19321 tttctgagaa ggagtttcat tatgaaagtt gttcgaaaat cactagcccc ctcttggtag
    19381 tggggctcct cttgacttct ctgatcagtt tgcatcagtt gaaggcagat aagaaaaaga
    19441 tgtctttcgt atcggtattt cgcaatttat tacccaccag tccttagacg ctactagaga
    19501 agaatttgtg gatgagctgg ccaaacaagg ctatgttgag ggggaaaata ttgagattga
    19561 tttgcaaaat gtacagggag aacaaagaaa tctaaaaacg atttcccagc aactagcaga
    19621 atccagcgat gtcgttctag ccatcgcaag gccttctgct cagagcttgg ccaatacgac
    19681 gcaaacgaca ccagttatct tttcagctgt aacagaccca gtcagtgcca agttggttga
    19741 gtcaagagaa catcctgggg gcaatgtaac tgggacaagc gatcagtcat cagatgccat
    19801 ttcaacccaa atcaatttga taaagaaagt gttgccaaag gctaaaacga ttggaatcct
    19861 ctatactcag agcgagccca attcggttgt ttaaaatgat gaagctaagc gacttctgaa
    19921 agaaaaaggc tttaccgttg ttgaaaaaac aatcttggac agtaataacg tcaaggcggc
    19981 agcagagagt ttgatggcag aggtggatat ggtttttgtc ccaactgata atatcatttc
    20041 gtcaaccatg gaaacagtta agcaggtttc tattaaacac aaggttccag tattcggtgg
    20101 ttcaacagaa atgattgctg ttggtgactt gtataactac ggaaccaatt atgaagaatt
    20161 gggaagacag acagctcgca tgctgattcg tgttttaaaa ggtgagaaac cagaaaatat
    20221 agcagttgag ttgcctgaaa aactggaatt gcataccaat caagaaatgg cagatgcatt
    20281 gggaattgat attagtaagt tagaaggcaa ggaataagga ggattaagat gaattttgtg
    20341 ttatctagtt tatcagaagg tttgttgtgg tcgattgtgg cgattggggt ctacttgact
    20401 ttccgtattt tggatattgc ggatataact gctgagggag cctttcctct gggggcagca
    20461 gtcgttgtat cacagataca ggcaggggca aatccttggc ttgcgacttt acttgctttg
    20521 ctggcaggta tggtagcagg tcttgtatca ggaatgctcc acaccaagat gaaaatccca
    20581 gctctcttga cagggattgt gaccttgaca gggctctatt caatcaatat taaaattatg
    20641 ggcagtgtac ccaatctttc cttgggagat tctgcaaccg tctttaaaca gttggcgagc
    20701 ttgggtctga caaatgaagg agctgttttc tcacttagtt tagtctgtct cttacttgtt
    20761 tggtcttgac ccttttgatg aaaacagaga ttggtttggt cttgcgttcg actggggata
    20821 atatcccgat aagtgaggcc aatggagtca atgtagacac catgaagatt gttggttaca
    20881 tgatttcaaa cggtttgatt gccctatgtg gttccttgtt tgcccaaaat gatggatttt
    20941 cagatgtgac ttctgggaca ggaaccattg ttgttggttt gagctcggaa gtcttgatac
    21001 acgacttgac cattggaggc cgcttattat ccatcggaat cggtgctatt gtttaccgtt
    21061 tgattatttt aaatatctat gaaattccaa atctagatca aaacttggta cgtctcttta
    21121 atgcaatctt gctcgctttg gttttatttg caccagaatt gcaaaagaga ttaaagattc
    21181 gtggtctgaa attgagaaat gaataggagg agaaagttat ggcaagtttg ttaacacttg
    21241 aaaatattca caagacattt gaagcaggga cggtcaatga gaaccatgtc ctcaaaggat
    21301 tagatttaga ggttgaagag ggagatttta tctatgtgat tggtggaaat ggagcaggaa
    21361 aatccacttt gatgaatatc ttggctggca atctatcggt ggacgaaggg gaccttctac
    21421 tggcagggaa atccattaaa aatctgagtg tcagaaagag agccaaggat attgcccgtg
    21481 tttttcaata tcctaagatg ggaacagctt ctcgtttgac gattgaggag aatatggcta
    21541 ttgccttgag acgtgggcaa aagagaggac ttggttgggg tgtgaaggag aaggatagaa
    21601 tccagttcca agaggccttg aaggagttga atattggtct tgaaaaccgc ttaaaagtag
    21661 atactcaata tctctcagga ggacaaagac aggctttgac cctagtcatg gcagctctgg
    21721 tgaaacccaa acttttactt ttggatgaac atactgcggc acttgacccg aaaaccagtc
    21781 aaatggtgat ggacttgacg caaaagattg tggagcacca tcagtggacg actttgatga
    21841 ttacccatga tatgaatcat gcgattgagt acggcaatcg tctcattatg ctctatcaag
    21901 gcaagatagt ggtggatgtc aagggagaag agaaaaagca tctgacagtt gaagacctta
    21961 tgcatctctt ccagaaaaat agtggccaaa gtctggtcag tgatgaatta gttttgggat
    22021 aaagaaaaag gctgagatct ggtgtctcaa tcttttattt cttgcgtttt gcaaaatcta
    22081 caaatctaaa tttttctaac ttatggcgac tttcggtaaa ctgaaattgg cgtccgtctt
    22141 ggagatagac ttttgattta atcgaaacga tataagggtc tttgccaatg tccatgagaa
    22201 tcttgtctcg gtcgcttgag tggtcgatgg tgatttcctt ctgagcataa tcaataagga
    22261 gtttgaggcc attttctata taagaataga tagactgctc agcaatttgg cgagtgagat
    22321 ttggaattag ttccatatcc agatagtccg tatccagaac ggataccaga tcatccacca
    22381 cacgctggcg gaccaccttc caaaccatcc gaaactctgg gaaaccggtt atcagtgagg
    22441 attttttatc aataataatc ttgtccagac tgaccacgtt ggttttagag cgcagtccaa
    22501 gttctttaac tagttcttgg tagctggtta ggttggatac agggaaattg acggtttctt
    22561 ctttgacgac ttgagaacct tgccctctta tctttttgat caatccttcc tcttggagga
    22621 gagacagggc ctttcggacg gtatcacgac tcacttgata ttgctccata aggtcgtgct
    22681 cgctaggaag gaaatctccg acagcgtaag tctcgttttg aatggtttct tggatttgct
    22741 taaataattg ttggtatttc ttcattttgc ctgctttaat aggtttttag tctagtttaa
    22801 tgaacacctg tatctatttt accatacaag tgctagaaaa tttacaaaaa aacacccttt
    22861 ttataccaaa caagttgcag acaagtttgg tatcgtttac aatatactta tcaaatcaaa
    22921 cttgctttga caagtataag gagaatcaaa tgggaaaatt tgaacaagaa gccaaagatc
    22981 tgcttcaggc aattggaggc aaagaaaatg tgactgccgt aactcactgt gcgacacgga
    23041 tgcgctttgt tttaagagat gataagaagg ctaatgttaa agctatcgag tcaattccag
    23101 ctgttaaagg aacttttaca aatgcaggtc aatttcaggt aatcattgga aatgacgtgc
    23161 ccatctttta taatgatttt acagccgttt caggtattga gggtgtttcc aaagaagcaa
    23221 ccaagtctgc agctaagagt aatcaaaacg tggttcaagg tgttatgacc actctggcgg
    23281 aaatctttac tccgattatt ccagccttga ttgttggtgg attgatcctc ggtttccgta
    23341 atgtcttgga aggtgtccat tggtcgatgt tggatggcaa gaccatcaca gaatcctctc
    23401 agttttgggc aggggttaat cacttcctct ggttgcctgg tgaagctatc ttccagttct
    23461 taccagtagg gattacttgg tctgtttctc gtaagatggg aaccagccaa attttgggaa
    23521 ttgttctcgg aatctgtttg gtatcgcctc agttgctcaa tgcctatgcg gttgcttcaa
    23581 cgccagcagc tgatatcgcg gcaaactggg tttggaattt tggttatttt actgttaatc
    23641 gtattggtta ccaagtccaa gttatcccag ccttgcttgc aggtttgagt ctgtcttatc
    23701 ttgaaatttt ctggcgcaaa catatcccag aagtcatttc catgattttt gtaccttttt
    23761 tgtcattgat tccagccttg attttggctc atactgtttt gggaccaatc ggttggacaa
    23821 ttggacaagg actttcatca gttgtcttgg caggtttaac tggtccagtt aaatggctct
    23881 tcggtgcaat ttttggtgcc ctctacgctc catttgtcat cacaggtctg caccatatga
    23941 ccaatgccat tgatacacaa ttgattgcgg atgctggtgg cactgcccta tggccaatga
    24001 ttgctctttc taatattgct caaggctcag ccgtgtttgc ctattatttc atgcatcgcc
    24061 atgatgagcg tgaggctcag gtttcacttc ctgcaaccat ttcagcctat ctcggtgtta
    24121 cagaaccagc tctttttggg gttaacgtaa aatatattta tccatttgtt gctgggatga
    24181 ctggttcagc ccttgcaggc atgttatccg ttacttttaa tgtaactgcg gcttctattg
    24241 gtatcggtgg tttgccaggt attctctcta ttcaacctca atacatgctg ccatttgcag
    24301 gaactatgct agttgcgatt gttgttccaa tgctcttgac tttcttcttc cgcaaggctg
    24361 gtctctttac aaaaacagag ggcgatacga acttgcaggc agaattcgtt gctcaagaag
    24421 aagcagaatt tgtgaaccat gaaccagtag aacttacttc ggtagaaatt atcagcccac
    24481 taactggcca agtgaaagaa ttgagtcaag cgacggatcc tatttttgca tcaggtgtca
    24541 tggggcaagg tctagtcatt gaaccaagcc aaggtgagtt gacctctcca gttaatggga
    24601 cagtgacggt tcttttccct accaagcatg ccatcggcat tgtctctgac gagggagttg
    24661 aattgctcat ccacatcggt atggatacag taggtcttga tggcaaaggt tttgaaagtc
    24721 ttgtagtcca aggagatcac gttacagttg gtcagcaact gattcgtttt gatatggatg
    24781 tcattaaggc tgcaggtctg gtgacagaaa ctcctgttat catcaccaac caagatgctt
    24841 atacagcgac tattcccgga acttatccga caacgatcca agctggagca tctctcatgg
    24901 tcgctacacg aatctaatac tcttcgaaaa tctcttcaaa ccacgtcagc tctatctgca
    24961 acctcaaaat agtgttttga gcaacctgtg gctagcttcc tagtttgttc tttgattttc
    25021 attgagtata attgaaatag cacaaatagg gacggaagac tgcttcctcc cttttatcag
    25081 aaaaggagaa acagatgaca cttgataaag gaaaagtagt ctatcaaatc tatccaaaat
    25141 cttacaaaga caccactgaa aacggtattg gggatttccg tgggattatc gaaaaaattc
    25201 cctatttagc caaactaggt gtggatatgg tctggctcaa tccattctat ccaagccctc
    25261 aacgggataa tggttacgat atttcagatt atatggcagt ggatcctctt tttggtgata
    25321 tggctgattt tgaggaaatg gtgtgtgtcg gtaaagagca caagattgac tttatgctgg
    25381 acatggtact taatcattgt tcgacagagc atgaatggtt tcagaaagcc ctagctggtg
    25441 ataagtatta tcaagacttt ttcttcatcc aagaccaacc aacagattgg cagtctaagt
    25501 ttggtggttc tgcatggacg cctttcgggg atactgggaa atactatctt cacctatttg
    25561 atgagaccca ggctgacctt aactggcgca attccaatgt ccgtaaggag cttttcaagg
    25621 ttgttaattt ctggcgcgac aagggtgtca aaggtttccg atttgatgtg atcaatttga
    25681 tcggtaagga cgaggtttca gtggactgtc ctgaaaatga agggaagcca gcttatacag
    25741 acaaacccat cgttcataac tatttgcgta tgatgaacca agccactttt ggatctgacg
    25801 atagctttat gacagttggg gaaatgtctt ctaccaccat ggaaaactgt gtcctctatt
    25861 cgtcgcctga tcgtcaggaa ttatccatga cctttaattt tcatcacctc aaggtggact
    25921 ataaggatgg acaaaagtgg accttggctc cctttgattt tgaagagttg aagagtcttt
    25981 accatagttg gggtaaggaa atgagtgata aagacggttg gagtgccctc ttttggaaca
    26041 atcacgatca accacgtgcc ttgaaccgtt ttgtcgatat tcaaaacttc cgcaaggaag
    26101 gagccaccat gctagcagcc agcattcacc tgtcacgtgg gacaccttat atctacatgg
    26161 gtgaggaaat cgggatgatt gacccagact atgattctat ggctgattat gtggatgtcg
    26221 aatcgcttaa tgcctatcag atgctcttag aagaaggaaa gagtcagcaa gaagccttcc
    26281 agattattca agctaagtcg cgtgataatt cacgcattcc catgcagtgg gatgcttcgg
    26341 aaaatgcagg attttcaaca ggcactcctt ggttgaaagc tggtaaatcc tataaataca
    26401 tcaatgtaga aaatgaaatc cagggtccga tttttacctt ctatcaagac ttgattcgac
    26461 tgcgtaagga aatgccaatc atttcagaag gaagttacaa accagccttt gaagatagca
    26521 aacaagtcta cgcttttgaa cgccagtttg aggatcaaaa gttactagtg ctcaataact
    26581 tttatgctaa agaagtggaa atcgacttgc cagcagtcta ccaaaatgga cagattttga
    26641 tatcaaacta tgaagatgca gaagtgtctg agaaaattct actcaaaccc tatcaaacac
    26701 tggctattta tgtaaattaa tactcttcga aaatctcttc aaaccgtgtc agttttatct
    26761 gcaacctcaa agcggtgctt tgagcaacct gtggctagct tcctagtttg ctctttgatt
    26821 ttcattgagt ataaacttag caaggagacc tctttttcag aaaagcaggg ttctttttgc
    26881 tgtctattcc atccctgaaa gtgtagaaca aactggtcag ggtggctagt ttgtggtata
    26941 atgaaaggaa ctcaaaaaga aacaggagaa aaatgatgga tttactttta gcaattgtat
    27001 tgattgtgct agcttttcta ggaggagctc ttggaggaat gtacttggtt cgtaagcaaa
    27061 tcgaaaaaga atttgctgac aacccacgtt tgaatgctga agcagttcgt actcttttga
    27121 gtgcaaatgg tcaaaaacca agcgaagcta aggtacaaca agtttaccac caaatcatcc
    27181 gccaacaaaa ggcagccctt gctaacaata aaaagaaaaa ataaataagg aaaagtctgg
    27241 gatgaaagtt ccagacttct cactatgttg gttatggttt agggatgaga ctttttcctt
    27301 gcattctatt gatatttgat tatgattaag agagaggtag ttgacattct atcaagctgt
    27361 cggtcagttc gttcagtaca aggaatcata atgaacgatc aatcagaaaa aagactagaa
    27421 agaagactgt atggataatc gaccaattgg ttttttggat tcgggtgtcg ggggcttgac
    27481 cgttgtgcgc gagctcatgc gccagcttcc ccatgaagaa atcgtctata ttggagattc
    27541 ggcgcgggcg ccctatggcc cccgtcctgc tgagcaaatt cgtgaatata cttggcagct
    27601 ggtcaacttt ctcttgacta aggatgtcaa aatgattgtc attgcttgta acactgcgac
    27661 tgcggtcgtc tgggaagaaa tcaaggctca actagatatt cctgtcttgg gtgtaatttt
    27721 gccaggagct tcggcagcca tcaagtccag tcaaggtggg aaaatcggag tgattggaac
    27781 gcccatgacg gtacaatcag acatataccg tcagaaaatc catgatctgg atcccgactt
    27841 acaggtggag agcttggcct gtcccaagtt tgctcccttg gttgagtcag gtgccctgtc
    27901 aaccagtgtt accaagaagg tggtctatga aaccctgcgt cccttggttg gaaaggtgga
    27961 tagcctgatt ttgggctgta ctcattatcc actccttcgc cctattatcc aaaatgtgat
    28021 ggggccaaag gttcagctca tcgatagtgg ggcagagtgc gtacgggata tctcagtctt
    28081 actcaattat tttgaaatca atcgtggtcg cgatgctgga ccactccatc accgttttta
    28141 cacaacagcc agtagccaaa gttttgcaca aattggtgaa gaatggctgg aaaaagagat
    28201 tcatgtggag catgtagaat tatgacaaat aaaatttatg aatataagga tgaccaggac
    28261 tggtatgttg ggtcttatag tatttttggt ggcgttaaca gtttgagcga ctataagaca
    28321 gattttcctc tgtttgaatt ctccaaaata tttggagatg aagagtatgg tttcccgctt
    28381 tcagttactg ttttacgcta tggttctacc taccgtttgt tctcctttgt ggtagacatg
    28441 cttaatcaag aaatgggacg aaacttggaa gttattcaac gtcatggggc cctgctcttg
    28501 gttgaaaatg ggcaactctt gtatgtagaa ttgcctaaag aaggggtcaa tgttcatgat
    28561 ttctttgaga caagcaaggt cagagaaacc ttgttgattg cgactcgtaa cgaaggtaaa
    28621 accaaggaat tccgagctat ctttgataag ttaggctacg atgtggaaaa tcttaatgac
    28681 taccctgacc tgcctgaagt agcagaaaca ggtatgacct ttgaagaaaa tgcccgcctt
    28741 aaggcagaaa ccatttctca attaacgggc aagatggttt tggcagatga ttctggtctc
    28801 aaagtcgatg tccttggtgg cttaccaggc gtctggtcag ctcgtttcgc aggtgtggga
    28861 gcaactgacc gtgaaaataa tgccaaactc ttgcacgaat tggccatggt ctttgaactc
    28921 aaggaccgct cggctcagtt ccacacaacc ctagtcgtag ccagcccaaa taaggaaagt
    28981 ttagttgttg aagcagactg gtcaggttat attaactttg aacctaaggg tgaaaatggc
    29041 tttggctatg atcccctctt ccttgtagga gaaacaggtg agtcatcagc tgaattaacc
    29101 ctggaagaaa aaaatagtca atctcaccgt gccttagccg ttaagaaact tttggaggta
    29161 tttccatcat ggcaaagcaa accatcattg taatgagcga ttcccatggc gatagcttga
    29221 ttgtggaaga agtccgtgat cgctatgtgg gcaaagtcga tgccgttttt cataacggcg
    29281 attctgaact acgtccggat tctccacttt gggagggcat ccgcgttgtt aaagggaaca
    29341 tggacttcta cgccggctac ccagaacgtc tggtgactga gcttggttcg accaagatta
    29401 tccaaactca tggtcacttg tttgacatca atttcaactt tcaaaagttg gactactggg
    29461 ctcaggagga agaggccgct atctgcctct atggtcactt gcatgtgcca agtgcttgga
    29521 tggaaggcaa gatcctcttt ctaaatccag gttctatcag ccaaccacga ggtaccatca
    29581 gagaatgtct ctatgctcgt gtggagattg atgatagtta cttcaaagtg gactttttaa
    29641 cacgagatca cgaggtgtat ccaggtttgt ccaaggagtt tagtcgatga ttgccaagga
    29701 gtttgagact ttcttgttgg ggcaggagga aacttttttg acccctgcta aaaatctagc
    29761 tgtgttgatt gatacccaca atgcggatca tgcgaccctc ttgctcagtc agatgaccta
    29821 tacccgtgtt cccgttgtga cagatgaaaa acagtttgtt gggacgattg gactcagaga
    29881 tattatggct tatcagatgg agcatgactt gagccaagaa atcatggcgg atacggatat
    29941 cgttcatatg acaaaaacgg acgtagcggt tgtttcgcct gatttcacca ttacggaggt
    30001 cttgcacaag ctagtagatg agtccttctt accggttgtg gatgcagagg gtattttcca
    30061 agggattatt acgcgcaagt ccatcctcaa ggccgttaat gccctcttgc atgactttag
    30121 taaggaatat gagattcgat gccaatgaga gacaggattt cagccttttt agaggaaaag
    30181 cagggcttgt ctgtcaattc caagcagtcc tataagtatg atttggagca atttttagac
    30241 atggtaggtg agcggatttc tgagaccagt ctcaagattt accaagccca gctagccaat
    30301 ctaaaaatca gcgcccagaa gcgaaagatt tcggcctgta accaatttct ctactttctc
    30361 tatcaaaaag gagaggtgga cagcttttac cgcttggaat tagccaaaca agctgaaaag
    30421 aagacggaaa agccagagat tctataccta gactcttttt ggcaggaaag cgaccatcca
    30481 gagggccgct tgctagcgct cttaatccta gaaatggggc tcttgcccag tgagatttta
    30541 gccatcaagg ttgcggacat caatctggat tttcaggtgc tgcgaatcag caaggcttcc
    30601 caacagagga ttgtcaccat tcccacggcc ttgctttcag aattggaacc cttgatgggg
    30661 cagacctatc tttttgaaag aggagagaaa ccctattctc gtcagtgggc ctttcgtcag
    30721 ttagaatctt ttgtcaagga gaaaggtttt ccatccttat cagctcaagt cttacgtgaa
    30781 cagtttattc taagacaaat agaaaacaag gtcgatttgt acgaaattgc aaaaaaatta
    30841 ggattaaaaa cagtcctgac cttagaaaaa tatagataat ggatattaaa ttaaaagatt
    30901 ttgaaggacc cctggactta ctcttgcatc tggtttctaa gtaccagatg gatatctacg
    30961 atgtgcccat tacggaagtc atcgaacagt atctagccta tgtctcaacc ctgcaggcca
    31021 tgcgtctgga agtgacgggt gagtacatgg tcatggctag tcagctcatg ctgattaaga
    31081 gtcgtaaact ccttccgaag gtagcagaag tgacagactt gggggatgac ctggagcagg
    31141 acctcctctc tcaaatcgaa gaatatcgca agttcaagct cttgggtgag cacttggaag
    31201 ccaagcacca agaacgggcc cagtattatt ccaaagcgcc gacagagttg atttacgaag
    31261 atgcggagct tgtgcatgac aagacgacca ttgacctctt tttggctttt tcaaatatcc
    31321 tagccaagaa aaaagaggag tttgcacaaa atcacacgac tatcttgcgg gatgagtata
    31381 agattgagga catgatgatt atcgtgaaag agtccttgat tggacgagat caattgcgct
    31441 tgcaggattt gttcaaggaa gcccagaatg tccaagaggt catcaccctc tttttggcaa
    31501 ccctagagtt aatcaaaacc caggagctga tcctcgtgca agaggagagt ttcggagata
    31561 tctatctcat ggaaaagaag gaagaaagtc aagtgcctca aagctagact tgatagagag
    31621 gaaagatgag tactttagca aaaatagaag cgctcttgtt tgtagcgggt gaagatggga
    31681 ttcgggtccg ccagttagct gaactcctct ctctgccacc gacaggcatc cagcaaagtt
    31741 taggaaaatt agcccagaag tatgaaaagg acccagattc cagtttggct ttgattgaga
    31801 caagtggtgc ttatagattg gtgaccaagc ctcaatttgc agagattttg aaggaatact
    31861 ctaaggcgcc tatcaaccag agcttgtctc gggctgccct tgagaccttg tccattattg
    31921 cctacaaaca gccgattacg cggatagaaa ttgatgccat ccgtggagtt aactcgagtg
    31981 gagccttggc aaagttgcag gcttttgacc tgataaagga agacgggaaa aaggaagtat
    32041 tggggcgccc caacctctat gtgactacgg attatttcct agattacatg gggataaacc
    32101 atttagaaga attaccagtg attgatgagc ttgagattca agcccaagaa agccaattat
    32161 ttggtgaaag gatagaagaa gatgagaatc aataagtata ttgcccacgc aggtgtggcc
    32221 agtaggagaa aagcagaaga gctgattaag caaggcttgg tgacggttaa cggccaagtg
    32281 gtgcgtgaac tagcaaccac tatcaagtca ggcgacaagg tcgaagttga aggtcaacct
    32341 atctacaacg aagaaaaggt ctactatctg cttaacaaac cacgcggtgt gatttccagt
    32401 gtgacagatg ataagggtcg caagacggtt gtcgacctct tgcccaatgt caaagagcgt
    32461 atttaccctg tgggtcgttt ggactgggat acatcaggtg tcttgatttt gaccaatgat
    32521 ggggacttta cagacgagat gattcaccct cgtaatgaga ttgacaaggt ttatgtcgcg
    32581 cgtgttaaag gtgtggccaa taaggacaat ctccgcccct tgacccgtgg tcttgagatt
    32641 gatggtaaga aaaccaagcc agctgtttat gaaattctca aagtggaccc agtcaaaaat
    32701 cgctctgtgg tgcagttgac catccatgaa gggcgtaacc atcaggttaa aaagatgttt
    32761 gaagctgttg gtctcaagta gataagttgt ctcggactcg tttcggacac ctagacttga
    32821 caggactccg tccaggagaa tcccgtcgtc ttaataaaaa agaaatcagc caactacaca
    32881 ccatggctgt aactaaaaaa taatgaaacg aattttaata gcgcctgtgc gcttttacca
    32941 acgttttatc tcaccagtct ttccaccctc ttgtcgcttt gagctgactt gttccaacta
    33001 catgattcag gctattgaaa aacatggttt taagggggta ttgatgggct tggctcggat
    33061 tttacgttgt catccctggt cgaaaacagg taaggatccc gttccagacc acttttccct
    33121 taaacgaaat caagaagggg aatgaggtgg ggtaaataga tttcaaaatg ataaaaacgc
    33181 atcctatcag gtttgagtga acttgatagg atgcgtttta gaatgtcaaa attttatact
    33241 cttcgaaaat ctcttcaaac cgcatcagct ttcatctgca acctcaaaac agtgttttga
    33301 gcaacctgcg gctagtttcc tagtttgctc tttgattttc attgagtatt aaattgagtt
    33361 tgaagtggct tatttcaaag ctttttgtat gtcttcaatc atgagttttg ttgattcaag
    33421 tccgcctccg cttagatacc agaggtctgg tgttagttgg ataatcttac catttttagc
    33481 agcaggtgtt tcagcgataa gggcattttc taggacaccg tcgttgctag agttgtcccc
    33541 accgatggca agggtacggt tgatgacaaa gaggatgtca gggttgattt ctttgacact
    33601 ttcaaagctg acttcttgtc cgtggcgtga gtcttcaaat tttgtatcag ttggtttgaa
    33661 tttcaaggtt tggtacaaga aagagaaacg agatttggca ccaaaggctg ccatttttcc
    33721 ttcattaagg aggatcgcaa gggctttttt gtcagagctt tcatttttag tagcgacttc
    33781 ttggatgctc ttgtctagct tggccaattc ttccttggct ttttgtatac tagtttcgcc
    33841 gaaggcactt gctaaggatt cgatattagc cttgatagaa gtccagtagt cgtccttgct
    33901 tgcttggaag agaacggttg gggcgatttc tttgaatttg tctacgaatt tttgtgtacg
    33961 tggtgaagcg ataatcaaat caggctcaag ggcggcgata gcttctaaat caggttcttt
    34021 catagaacca acatttttga cagttcccac taggtctttt agataagtcg gaatagtttt
    34081 tgtaggcatt ccgatgatat ttttttcaaa tcctaaagcg cgaatagtat ccgcagcgcc
    34141 gaggtcaaag gtcacaatct tttcaggaac tttggaaagt ttgacctcgt ccagtgaact
    34201 tttaatggtt acctctgttg gagcagagct actggtctct gtctgactag tgcttgagtt
    34261 tgtactacat gcaccaagta ggagcaagaa gctggccact agggcagtga aataaagttt
    34321 aagggatgtt ttcataattt ctccttttta aaatgtgata acgatttagg gagtctctta
    34381 atcttattga ctaagagact gaaggttctc taacttgagc ttttatgtta ctagctatag
    34441 atacagatct ttttgtcatt gatatcagct agcgtgatgg gaatctcata aagttgactg
    34501 agcaggtcag cctgcatgat ttgatcggtt cttcccttgc taaagacctg gccgtccttg
    34561 aaggcgacaa tttcatctgc atactgactg gccatgttga tatcgtggag gacgatgata
    34621 atggtcttgc cgagttcctc caccagtcgt cgaagaatct gcatcatgct gacgctttgc
    34681 ttgatatcga gattgttgag tggttcgtcc agcaagataa agtccgtatc ctgggccagt
    34741 accatagcga taaagacgcg ctggagttgc ccccctgaca ggctattgat gtagcggtct
    34801 tttaagttgg tcagttccaa atagttcaga gtttctcgga ttttttccca gtcttctgat
    34861 ctaagtcgac ctcggctgta gggaaaacgt ccaaaactga ccagttcttc aacagtcaat
    34921 ttggcttggt aattgatttt ctgttttagg atggttagtt cttgggccag ttcttgcgaa
    34981 ttccagctct cgatttcacg tcctttgata ctgagaactc cctgatcttt cttggttagt
    35041 ctgctcatga tggagaggag agtcgatttt ccagcaccat ttggaccaat aaaggctgtc
    35101 agtttttgag gactgacttc aagcgaaatg ccttgcaaaa tatcctgttt ttgaatggat
    35161 ttgtcaatgt tttccagttt cactgacgag acctcctata tagtaagata aagaataaga
    35221 agccacccac actctcaatg atcatactga tacgaatttc cagtgcaaag actcgttcaa
    35281 tcaaggcttg ccccaaggtt aagctaataa atccaaccag aatggccact ataaagagta
    35341 acttgtgctg atagtctttg acaatcaggt aggtgaggtt agccagcata aagccgaaga
    35401 aggccatagg tcctaccaag gcagtggccg ttgaggtcaa aagcacgatt ccccagagga
    35461 gctctttctg ttctttttca acatcgagtc ccaatatctg agccgtttct ctttgcaggt
    35521 gcaagacatc tagaacgact gcttttcgaa agaaaaagat tgtcaaagcg aggatgatca
    35581 gagaaccgat ggctaggatg gaagtgttga gatgttgaaa ggaggcaaaa agactatttt
    35641 gcagtttatc gtattcgttt ggatccatta ggacttgaag gaaggtgcta atatttcgaa
    35701 agagacttct gagcgctaga cagatcagca ggatgaagac caggtcttgc ttcatcagtg
    35761 tcttcaagta accttgtaag gcgagaaaga agaaggactg gacaagaagt aagactagga
    35821 attctaagat aggggatttg ccaagttgaa gaaacttgct ttcaaaaacc agtagtaggg
    35881 tttgtagtag gacgtagaag gattcaattc ccaaaatact aggcgtcagg aagcgatttt
    35941 ccgtcagggt ttgaaaacta atggtcgaaa tcccagtcgc gatggctacc aagagataaa
    36001 cgatgatctt ttgggaacgc aacttccaag caaaggctga caagtgagtg atgggccaaa
    36061 agtagagaag acaagctccg atggcaagaa taatgagaat ccagaagagc ttggtatgtt
    36121 tgcttttagt ctgcatcttt tcgtccccct ctccagagaa gtaggataaa gacgagacta
    36181 ccgatgattc ctagcaagag actgacagac aactcatagg gcctaatcag aactcgggat
    36241 aggatatcgc aagccagaac tagattggca ccaaccagtg cgaccatgag tttggtttga
    36301 cttagattat ctccatagcg cttgcgaaca agattgggaa cgataactcc gagaaatggt
    36361 aagccaccca cggtaatcat ggtgacgctt gtcgttagcg ccaccagaaa gagggccagt
    36421 ttttcaagta gggagtagga aatccccaaa ctctcgctgg tttctttccc cagattcatg
    36481 atggtgaagg tttgggataa tttccaaacg gttatcagga tgatgaggcc taagaagagc
    36541 cactcatact gatgggtctg aatcatggag aaggagccct gggtccaggc agtcatactc
    36601 tgaaccagat tgaaacgata ggcgataact tctgtgactg agccgataat cccgctatag
    36661 atgatcccaa tcagaggcaa catccacctt tcctttacag taaaaatggt cataaaggct
    36721 aggaagaaga gggtgaatac gatggatgaa acaaaagcga agagcatctt ttgggtcaga
    36781 ctagccgatg gaaagacaaa aaggctcagc accattccca gtttggcggc ttcagtcgtt
    36841 ccaactgtac tcggtgcagc aaactgattt tgggtaatag tctgcatgag aaggcctgcc
    36901 atactcatac tagaggcagt caggagaata ctgatagttc ttgggagacg ggactcttga
    36961 aagaggagcc aggtctgctg gtcgaaatca aatagctttc cccatgaaaa atcactggtc
    37021 ccaatgctaa tagagagaaa gactaggagt agaagtaagc caattaaata atgagaaagt
    37081 ttcatacccc gtcctttcat gtagatttgg tatcgaaaga tatctgcgga tataaatgta
    37141 acattatttt tctaatctgt caataaaatt tctgacaatt taataaatac aacaaggaga
    37201 gagcaacaag actttctcct ttgttatcct attctaaaat gtttttacct taatctgata
    37261 aaataatatc ttcgagggag tagctagccg tccaatcaag atattgttta gcttttgaag
    37321 catctgctag gacactggct gggtcactag cacgtcgagc aacaatctcg tgtgggattt
    37381 tttaatttag taattcttca gcagttttaa agatttcttt gatagtatag ccttttttag
    37441 tttctaagtt aaagatttga gaagaactgt cttcttgaaa taggtagttc attcctttaa
    37501 catgagccta tgcaaggtcc aagacataaa tgtaatctcg aatacatgaa ccgtcacgtg
    37561 tatcgtagtc atctccaaat atttttaagc tatcattttg tcccaatgcg gtcttgttga
    37621 tatttggaat gatgtgagtt ggatttttca cacgcagacc gtttgaagca tccatttcag
    37681 ccccagcagc attaaagtaa cggaaaataa catatttcca gtcgtagcga ttggccatcc
    37741 agtaaatcat tcgttcgccc atcagttttg tctctgcata agggttgaca gggtcgagca
    37801 gggtatcttc agtcaccggc ttgtcaatac agttatttcc atagagagaa gcagtcgaag
    37861 agaacatgat tttttgaatg ccaacttcag ataagacttt gagaacttgg ttcataccag
    37921 caacgttggc agtgaagtat ttacttggat tttcaatact ttcgctcaca acagtttcac
    37981 ctgcacaatg gagggcagca tcaatctgat tttcttctaa gtaagacttt aaggcgctag
    38041 catcataaac atccagttct ttaaagctag cacgactatc cacagccgct cgatttcctg
    38101 tagagagatt atcgaggaca tgcacctgat agccagcatt taaaagagct ttaacggtat
    38161 gggagccaat gtagccagtc tcacctgtaa caagaattgt tttggtcatg attttttcct
    38221 tttctagttt tgtactatag tagattgaaa taagatatga a
//
LOCUS       DBJKQU010000013        37043 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.013, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000013 DBJKQU010000000
VERSION     DBJKQU010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 37043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37043
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.013"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            1..467
                     /locus_tag="ACSUUC_000789"
                     /pseudo
     CDS             1..467
                     /locus_tag="ACSUUC_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            551..1258
                     /locus_tag="ACSUUC_000790"
     CDS             551..1258
                     /locus_tag="ACSUUC_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHQ8054036.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1259..2590
                     /gene="pnpS"
                     /locus_tag="ACSUUC_000791"
     CDS             1259..2590
                     /gene="pnpS"
                     /locus_tag="ACSUUC_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HHQ8054037.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2757..3632
                     /locus_tag="ACSUUC_000792"
     CDS             2757..3632
                     /locus_tag="ACSUUC_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HHQ8054038.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3750..4613
                     /gene="pstC"
                     /locus_tag="ACSUUC_000793"
     CDS             3750..4613
                     /gene="pstC"
                     /locus_tag="ACSUUC_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HHQ8054039.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4606..5421
                     /gene="pstA"
                     /locus_tag="ACSUUC_000794"
     CDS             4606..5421
                     /gene="pstA"
                     /locus_tag="ACSUUC_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HHQ8054040.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5423..6175
                     /gene="pstB"
                     /locus_tag="ACSUUC_000795"
     CDS             5423..6175
                     /gene="pstB"
                     /locus_tag="ACSUUC_000795"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HHQ8054041.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6190..6840
                     /gene="phoU"
                     /locus_tag="ACSUUC_000796"
     CDS             6190..6840
                     /gene="phoU"
                     /locus_tag="ACSUUC_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HHQ8054042.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            6881..7333
                     /locus_tag="ACSUUC_000797"
                     /pseudo
     CDS             6881..7333
                     /locus_tag="ACSUUC_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826904.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7448..7582)
                     /locus_tag="ACSUUC_000798"
     CDS             complement(7448..7582)
                     /locus_tag="ACSUUC_000798"
                     /inference="COORDINATES: protein motif:HMM:NF037495.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054043.1"
                     /translation="MFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW
                     "
     gene            complement(7771..7887)
                     /locus_tag="ACSUUC_000799"
                     /pseudo
     CDS             complement(7771..7887)
                     /locus_tag="ACSUUC_000799"
                     /inference="COORDINATES: protein motif:HMM:NF013540.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            8099..9115
                     /locus_tag="ACSUUC_000800"
     CDS             8099..9115
                     /locus_tag="ACSUUC_000800"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HHQ8054044.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKPYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVAVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9137..10036
                     /gene="galU"
                     /locus_tag="ACSUUC_000801"
     CDS             9137..10036
                     /gene="galU"
                     /locus_tag="ACSUUC_000801"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-alpha-D-glucose metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HHQ8054045.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDEATGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHAST
                     IAVMPVPHEDVSSYGVIAPQDEGKDGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFARKFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(10103..10780)
                     /locus_tag="ACSUUC_000802"
     CDS             complement(10103..10780)
                     /locus_tag="ACSUUC_000802"
                     /EC_number="3.4.21.-"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HHQ8054046.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYMTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRLYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(10764..11303)
                     /locus_tag="ACSUUC_000803"
     CDS             complement(10764..11303)
                     /locus_tag="ACSUUC_000803"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HHQ8054047.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDLQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(11315..12445)
                     /locus_tag="ACSUUC_000804"
     CDS             complement(11315..12445)
                     /locus_tag="ACSUUC_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HHQ8054048.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEAGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(12513..13211)
                     /gene="dapD"
                     /locus_tag="ACSUUC_000805"
     CDS             complement(12513..13211)
                     /gene="dapD"
                     /locus_tag="ACSUUC_000805"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HHQ8054049.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(13441..14352)
                     /locus_tag="ACSUUC_000806"
     CDS             complement(13441..14352)
                     /locus_tag="ACSUUC_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HHQ8054050.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(14417..16882)
                     /gene="pbp1b"
                     /locus_tag="ACSUUC_000807"
     CDS             complement(14417..16882)
                     /gene="pbp1b"
                     /locus_tag="ACSUUC_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HHQ8054051.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALVPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            17024..18280
                     /gene="tyrS"
                     /locus_tag="ACSUUC_000808"
     CDS             17024..18280
                     /gene="tyrS"
                     /locus_tag="ACSUUC_000808"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HHQ8054052.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(18358..20421)
                     /locus_tag="ACSUUC_000809"
     CDS             complement(18358..20421)
                     /locus_tag="ACSUUC_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HHQ8054053.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YSIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(20423..20701)
                     /locus_tag="ACSUUC_000810"
     CDS             complement(20423..20701)
                     /locus_tag="ACSUUC_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HHQ8054054.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            20853..21701
                     /locus_tag="ACSUUC_000811"
     CDS             20853..21701
                     /locus_tag="ACSUUC_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HHQ8054055.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            complement(22040..22255)
                     /locus_tag="ACSUUC_000812"
     CDS             complement(22040..22255)
                     /locus_tag="ACSUUC_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054056.1"
                     /translation="MCYYVKKYFSKYKWTDLFWILFVILTCLYIGNHDLFTLNHQEFS
                     FRGSVWGLVLALYHLLFIDKFVISNRK"
     gene            22322..22894
                     /locus_tag="ACSUUC_000813"
     CDS             22322..22894
                     /locus_tag="ACSUUC_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054057.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGIYLAQLWDKNDAIPNNGRINF"
     gene            complement(23939..26197)
                     /gene="glgP"
                     /locus_tag="ACSUUC_000814"
     CDS             complement(23939..26197)
                     /gene="glgP"
                     /locus_tag="ACSUUC_000814"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HHQ8054058.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGENSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(26223..27755)
                     /gene="malQ"
                     /locus_tag="ACSUUC_000815"
                     /pseudo
     CDS             complement(26223..27755)
                     /gene="malQ"
                     /locus_tag="ACSUUC_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            28290..29561
                     /locus_tag="ACSUUC_000816"
     CDS             28290..29561
                     /locus_tag="ACSUUC_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HHQ8054059.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            29672..30964
                     /locus_tag="ACSUUC_000817"
     CDS             29672..30964
                     /locus_tag="ACSUUC_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HHQ8054060.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            30966..31808
                     /locus_tag="ACSUUC_000818"
     CDS             30966..31808
                     /locus_tag="ACSUUC_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HHQ8054061.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            32061..32861
                     /locus_tag="ACSUUC_000819"
     CDS             32061..32861
                     /locus_tag="ACSUUC_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HHQ8054062.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            32871..33857
                     /locus_tag="ACSUUC_000820"
     CDS             32871..33857
                     /locus_tag="ACSUUC_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHQ8054063.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(34193..35134)
                     /locus_tag="ACSUUC_000821"
     CDS             complement(34193..35134)
                     /locus_tag="ACSUUC_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHQ8054064.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(35112..36875)
                     /gene="aspS"
                     /locus_tag="ACSUUC_000822"
     CDS             complement(35112..36875)
                     /gene="aspS"
                     /locus_tag="ACSUUC_000822"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HHQ8054065.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT        11182 a         7972 c         7029 g        10860 t
ORIGIN      
        1 agacttgata agaactctag agttagctcc ccatgttgaa ggtggctatt ttagacaaac
       61 aaaaaaagct tcagacacta taaaccttgc tggtaaggga agggcgcttt ataccagtat
      121 ttatttctta ttaagaagaa acgaatcctt cacattttca ccgattgaca gcagatgaaa
      181 tctggtattt tcatgcagga tccccactta ctgttcacat gatcacagca gatggtcact
      241 acgaagcagt cactttaggc ctggacatat ccaaagggca acaacttcac tactgtgttc
      301 ctaagggcac tatttgggga tcaacagttg ataaggatga tgctctggtt tcttgtcttg
      361 ttgctcctgg ttttgaattt gaggattttg aattatttga aagggtagat ctactggcga
      421 cctatccaga gcacaaggag atgattgagc gtttgaccag atactagtct tgataagcaa
      481 atttaatctg atttagcaat gttaggattt ctgataattg tgttataatg ttaccaatag
      541 gagataatag atgacaaaac aagtcttatt agtggatgat gaagaacaca ttctgaaatt
      601 gcttgactac catttaagta aggaaggctt ttctactcaa ttggtaacaa atggacggaa
      661 ggccttagct ttggcagaaa cagaaccctt tgattttatc ttgcttgata tcatgttacc
      721 acaattagat ggcatggaag tttgtaagcg gctgagagcc aaaggcgtca aaactccaat
      781 tatgatggtt tctgcgaaaa gtgatgaatt tgataaggtt ttggccttgg aattaggggc
      841 tgatgactac ctgaccaagc cttttagccc tagagaattg ctggcgcgtg tcaaggctgt
      901 cctcaggcga actaaaggag aacaagaagg agatgattca gataatatcg ctgacgattc
      961 ttggctattt gggaccttga aagtataccc tgagcgtcat gaagtctaca aggcgaataa
     1021 gttactgagt ttgaccccaa aagaatttga actcttgctc tatcttatga aacatcccaa
     1081 catgacactg actagagagc gtcttttgga acgtatctgg gggtatgact ttgggcagga
     1141 aacacgtttg gtggacgttc atattggtaa gttgagggaa aaaattgaag acaatcctaa
     1201 agcccctcaa tttattcgaa ccattcgggg ttatggttat aagttcaagg agttatagat
     1261 gaaacgctac cttcaatttt ggctagtcaa tctaagtgtt agcctcattc tgattgcagg
     1321 gatggcatta acttggatca gtaaaggcat cggtctcttt cttctagccc tttctttggg
     1381 acaaggtggc tactggctct tttgcctttg gaaatgggaa gttgcttttg agaccttgca
     1441 ccaacctctc ttgaccagta gtgaatactt tttagaaaaa gggcaagaag acttaaagtc
     1501 tttggctcag tatgtgtctg gcctaaaaac caaagtctcc caacaggatc agcaatacaa
     1561 ggacctagcc gaaacaatgg aggttcttct gtcgcaccta accatgggga cgtttttagt
     1621 ttccgctcaa ggtcagatgt tattatccag tcgctctctg cctcattatt ttcccgatgt
     1681 ggacggcgac ataagttcac ttgatgacct caaacggatg gatattcgaa atttagttca
     1741 ccaagccttt gatcaaaaaa caaggttaaa acaagaagta agtgggtttc atgagggtga
     1801 cttgatttta gaagtaacag cagttcccgt ttttagcccc acccaatctg tggaagctgt
     1861 gctcgtcttg ctatatgatt taacaacgat tagaacttat gaaaagttaa atttagcctt
     1921 tgtctcaaat gcctcccatg aattgaggac accagttact tcgattaagg gctttgctga
     1981 aaccattaag gggatgtcag ctgaagaaga agcgctcaag gatgactttc tagacattat
     2041 ttacaaagaa agtttgcgtc ttgagcatat tgttgagcat cttcttacct tatctaaggc
     2101 tcaacaaatg cctatacaat ggacgaccct ttctttggca gaatttgtac aggatttgac
     2161 tcaaagcttg caacctcagc tcaagaagaa ggatttacag ctaaaggtgc aggtgccaga
     2221 tgatgtcacc ctcgtatcag atagtcaatt actttcccaa atcttactca atcttttatc
     2281 caatgccatc cgttacactg aacaaggggg aaaaattgag gtcaagaccc aaaaggtgaa
     2341 cgaaggcatt aagatttctg tatcagatac agggattggt attagtcaat tagagcagga
     2401 tcgtattttt gaacgttttt accgagttaa taaaggtcga agcagacaaa ctggtggcac
     2461 tggtcttggc cttgccattg tcaaagaact cagtcaatta ttaggtggcc aagtcacggt
     2521 gacgagtcag cttggcagag gcagttgctt cacgattttt cttcctaacc aatctttcgc
     2581 acaggactaa taatttttaa agctattttt aggagcagcc atttttcaaa agtggctttt
     2641 tttgattctt tacacaatct ttacatgaat cagggataaa cctttacaaa gacttgttag
     2701 actataaatg tagtaagcct acacaagaaa aatacataga gataaaggtg attattatga
     2761 aattcaaaaa aatgcttact cttgcagcca ttggcttatc aggatttggg cttgttgcct
     2821 gtggcaatca gtcagctgct tccaaacagt cagcttcagg aacgattgag gtgatttcac
     2881 gagaaaatgg ctctggaaca cggggtgcct tcacagaaat cacagggatt ctcaaaaaag
     2941 acggtgataa aaaaattgac aacactgcca aaacagctgt gattcaaaat agtacagaag
     3001 gtgttctctc agcagttcaa gggaatgcta atgctatcgg ctacatctcc ttgggatctt
     3061 taacgaaatc tgtcaaggct ttagagattg atggtgtcaa ggctagtcga gacacagttt
     3121 tagatggtga ataccctctt caacgtccct tcaacattgt ttggtcttct aatctttcca
     3181 agctaggtca agattttatc agctttatcc actccaaaca aggtcaacaa gtggtcacag
     3241 ataataaatt tattgaagct aaaactgaaa ccacagaata tacaagccaa cacttatcag
     3301 gcaagttgtc tgttgtaggt tccacttcag tatcttcttt aatggaaaaa ttagcagaag
     3361 cttataaaaa agaaaatcca gaagttacga ttgatattac ctctaatggg tcttcagcag
     3421 gtattaccgc tgttaaggag aaaaccgctg atattggtat ggtttctagg gaattaactc
     3481 ctgaagaagg taagagtctc acccatgatg ctattgcttt agacggtatt gctgttgtgg
     3541 tcaataatga caataaggca agccaagtca gtatggctga acttgcagac gtttttagtg
     3601 gcaaattaac cacctgggac aagattaaat aaaatgtttg ctccataaat ctctaaagag
     3661 atgcagacgt ttcatcgtac aataagataa agaaggcaag tagggaggtg tcgtatctcc
     3721 cttactttct tcactagaaa ggacaagatg tgacaaaaca agccttcaaa gaagcagttt
     3781 ttagggcaat ttttttcatg agtgcaacag tagctgttgt agctattttg ctaatctgtt
     3841 tctttatttt tagtaatggc ttacctttca tagctaacta cggctttgcc cgttttttat
     3901 taggcagtga ttggtcgcca acgaacattc cggcaagcta tggtatttta ccaatgatcg
     3961 ttggttcctt attaattacc ttaggagcga ttgtgattgg ggtgccaaca ggcatcttga
     4021 catcggtgtt tatggtttat tattgtccaa agcccgtcta tggcttctta aaatcagcta
     4081 tcaacttgat ggcagccatt ccatctattg tttatggttt tttcggccta caattattgg
     4141 tgccttggat tagaagcttt ttaggaaatg gcatgagtgt cctaaccgct tcgttactat
     4201 taggaataat gattttgcca actattatca gtttgtcaga atctgctatc cgaacagttc
     4261 ccaaaacgta ttattctggt agcttggctc taggagctag tcatgaacgg agtattttta
     4321 gtgtcatctt gccagctgcg agatctggta ttttatcagc agttatttta ggaatcggtc
     4381 gcgcagtagg tgaaaccatg gcagttatct tggtggcagg caaccagccg attattccaa
     4441 gtggactctt ttcaggaacc agaaccttaa caaccaatat tgttctggaa atggcttacg
     4501 catcaggtca gcatagggaa gcccttattg caacctcagc agttctcttt ttccttattc
     4561 tcttgattaa tgcctacttt gcctacttga aaggaaaatc atcttatgag taaatacctg
     4621 ctaaaacttc tcgtttattg tttttcagct ttaacctttg gctctctctt tttaatcatt
     4681 ggttttatcc tcatcaaagg cttacctcat ctaagtctat ccctcttttc ttggacttat
     4741 acttctgaga acatttccct tatgccagcg attatttcca ccgttattct ggtctttggt
     4801 gctcttcttt tagccttgcc catagggatt tttgctggtt tttatcttgt ggaatataca
     4861 aaaaaagatt ccctttgtgt taaaatcatg cgattggcct cagatacctt gtctgggatt
     4921 ccttccattg tttttggtct gtttggcatg ctcttctttg tagtcttctt aggttttcaa
     4981 tactctctgt tatcaggaat cttaacctca gtcatcatgg tgttgccagt cattattcgc
     5041 tcaacagaag aagccctttt atctgttagt gatagcatgc gtcaagcaag ttatggactt
     5101 ggggcaggta agttacggac tgtttttaga attgttctac cagttgccat gccaggtatt
     5161 ttagctggag tgatactagc tattggccgt atcgttggtg agacagctgc cctcatgtat
     5221 acattaggta cctctaccaa tacgccaagt agtctcatgt cttcaggtcg ttctctagcc
     5281 ctgcatatgt atatgctgtc aagtgagggg ctacatgtca atgaagccta tgctaccggt
     5341 gtgattttga ttattactgt tttaatgata aatactctat caagcttatt atctcgaaaa
     5401 cttgtgaaag gagcttccta gtatgggaac attttcagtt agacacctag acttatttta
     5461 cggggatttt caagccttaa aaaatatttc gattcaatta ccagaaaggc agattactgc
     5521 cttgataggc ccatctggtt gtggcaaatc aacttttcta aaaaccctta accggatgaa
     5581 cgatttggtt ccttcttgcc atattgaagg ccaagtcctc ttagatgagc aagatattta
     5641 tagtagcaaa ttcaacctta atcagctacg taagcgtgta gggatggttt ttcaacagcc
     5701 taatcccttt gccatgtcta tctatgataa cgtggcttat ggcccaagga cacatggtat
     5761 tcgagacaaa aaacaattag atgccttagt ggagaaatct ttaaaagggg cagccatttg
     5821 ggaagaagtc aaagatgatc ttaaaaagag tgccatgtcc ttatctggcg gtcagcagca
     5881 acgcctttgc attgcgcgag ctttagcagt agaacctgat attctgttaa tggatgagcc
     5941 gacttcagcc ttagacccta tctccacttt aaaaattgaa gacctcattc agcaactaaa
     6001 aaaagattat acgattatca ttgttaccca taacatgcaa caagcttcac gtatttcaga
     6061 taaaactgct tttttcttaa caggagaaat ttgcgaattt ggagataccg ttgacgtgtt
     6121 taccaatcca aaagatcagc gcacagaaga ctatatttca ggacggttcg gataaggaag
     6181 gaaaaaccta tgagaaatca atttgactta gaattgcatg aattagaaca atccttttta
     6241 ggactagggc aacttgtcct tgaaacagct tcaaaagcct tactggcctt agcctccaaa
     6301 gacaaggaga tggcagagct aattatcaat aaggatcatg ctatcaacca aggtcaaagc
     6361 gctatcgaat tgacctgtgc ccgtttgttg gccttgcagc agccacaagt gtctgacctt
     6421 cgatttgtga ttagcatcat gtcttcttgt tcagaccttg aacgtatggg agaccatatg
     6481 gcaggcattg ccaaagctgt tttgcaacta aaagaaaatc aactagcccc tgacgaagaa
     6541 cagttacacc aaatgggtaa attatccctc agcatgctag ccgatttatt ggttgccttt
     6601 cctttgcacc aagcctcaaa agctattagt attgctcaaa aagatgaaca gattgaccaa
     6661 tattattatg ccttatcaaa ggaaatcatt ggacttatga aagaccaaga aacctcaatt
     6721 cccaatggaa cacaatacct ttatatcata gggcatctgg aacgcttcgc tgattacatt
     6781 gctaacattt gtgaacgcct agtctaccta gaaacaggag aactagtgga tttgaattaa
     6841 ttcaactaat ccttaaaaga gaagagtacg attaagtgct cttttttatg gttgtaaaaa
     6901 agttcatttg aacaatttaa gcagtgtaga tagtgaggag ctgtttcaat tctatcgtga
     6961 acgagggaat gctgaaaact ttatcaaaga aaggaaagca ggattctttg gggataagac
     7021 agatagttcg accatgatta agaatgaagt acgtatgatg atgggctgtc tggcttataa
     7081 tctctacctc tttttaaagc agctagctgg tgatgaagta aaggccttga ctatcaagcg
     7141 ttttcgacgt ctcttccttc atattgccgg aaaatatgtc tctactgcta gacgacatat
     7201 tctcaaattc tcaagtctat atgcctcttc aaaacagttt caagccttat ttgatacaat
     7261 ctgccagata aatctgatac tccctgttcc atatagagct agagggcagg ggaaaacatg
     7321 cctaacagaa taagtcacct tattttaaaa atcgagcatc aaaccaaggg aggagtctgc
     7381 ccttttttag gaaaaaatca agacaaatct cctcaattat gtctcgaaca tcagaaatta
     7441 agcaaaatca ccagaaggac agtatttcaa ctagcttttc tggtaatttt tgaactgtgt
     7501 agttcgttag tgccagatat gaataatttg ggatgataaa tctttcttcc tcaggtagcc
     7561 tatcataata ctcttcaaaa atcttatcaa aacactctct ttcttttggg cgatagtttc
     7621 atcttcgtat gtaggagtcc tcatcaagaa atacttcaat tctaggtatt ccttatccaa
     7681 ctctatataa cttggcatca acttgtaatc ttcaaccccc aaacgttcag cgatatattt
     7741 taactttgtt agtgttggtc tggattctcc attttcaatt ctaattaatt gacggatact
     7801 taattcagac tcatcaccac aaaattctga acgactgatt tttttagcca aacgtaatct
     7861 tttaattttt tcgccaaact ttcgcaacct acaagaacct cctgagttgt ttacctctat
     7921 ttatagcata tactgaatca aactatctat cagatttctt ctcactttaa ctaaagacta
     7981 agagtttatc ccttcatctc gatctttgtg tatttttcca ccatacccca gtaatgcaag
     8041 tgcaaaatcc cctagaatat gatataataa gagaaagaaa tctatcaagg aggaaatcat
     8101 ggaaaaacaa accgtcgccg tcttggggcc tggttcttgg ggaaccgccc tttcacaagt
     8161 cttaaatgac aatggacacg aggtacgtat ttggggaaat cttcccgagc aaatcaatga
     8221 aattaataca caccatacta ataagcccta ctttaaagat gtcgttctag acgaaaatat
     8281 cattgcctac accgacttag cagaaacatt gaaaaatgtg gatgcgattt tgtttgttgt
     8341 cccaacaaaa gtgacacgac ttgttgccca gcaagttgca caaaccttgg accataaggt
     8401 tatcatcatg cacgcatcaa agggattaga acctgatagc cataaacgat tatcaaccat
     8461 tcttgaagaa gaaattcctg aacatctccg tagtgatatc gtcgctgttt cagggcctag
     8521 tcatgcagaa gagaccattg tgcgtgacct aactttaata actgctgctt ctaaagattt
     8581 acaaacagct caatacgttc aggagctatt tagtaatcac tacttccgac tttataccaa
     8641 tacggatgtt atcggggttg aaactgctgg tgctcttaaa aatattattg ctgtcggtgc
     8701 tggagcttta catggtcttg gatttggtga taatgctaag gcagccatca tcgctcgagg
     8761 tttagcagaa atcacccgcc taggggtagc actcggggcc agtccattga cctatagcgg
     8821 cttatctggt gtgggagatt tgatcgtaac gggaacttcc atccactctc gtaactggag
     8881 agctggagat gctctcggac gaggagaatc cctagctgat atagaagcta atatgggcat
     8941 ggtaatcgaa ggaatttcaa cgactcgagc agcctatgaa ctagcccaag aacttggagt
     9001 ctatatgccc attacacagg ctatttacca agttatttat cacggaacca atatcaaaga
     9061 tgccatttat gacatcatga acaatgaatt taaagcagaa aatgagtggt cttaaccctc
     9121 tatagaaagg atttttatga catcaaaagt tagaaaggca gttatccctg ctgctggact
     9181 aggaactcga tttttaccag caaccaaggc ccttgccaaa gaaatgttgc caatcgtaga
     9241 caaaccaact atccagttta tcgtggaaga ggctctcaaa tcaggtattg aagatattct
     9301 agttgtcact ggtaaatcaa aacgttctat tgaggaccac tttgattcaa actttgagct
     9361 tgaatacaat cttaaggaaa aaggcaaaac ggatttgtta aaattggtag atgaagcaac
     9421 tggcatgcgc cttcatttca tccgccaaac tcaccctcgt ggtcttggag acgctgtctt
     9481 acaagccaaa gcttttgtag gaaatgaacc cttcgttgtt atgctgggtg atgacttgat
     9541 ggacatcaca gacgagaagg ccgttccttt gacaaaacaa ctgatgaatg attacgaaaa
     9601 gacacacgca tcaaccattg ctgtcatgcc cgtaccacac gaagacgttt catcatatgg
     9661 agtcattgct cctcaagacg aaggaaaaga tggtctttac agtgttgaaa cctttgttga
     9721 aaaaccagct cccgaggaga ctccaagtga tttggcaatc atcggtcgct atctactcac
     9781 accagaaatt tttgagattc tcgaaaagca agctcctggt gctggaaatg aaatccaact
     9841 tactgatgca atcgatactc ttaataaaac acagcgtgtt tttgcccgta aatttacagg
     9901 agctcgttac gacgttgggg ataagtttgg ctttatgaaa acatctattg actacgccct
     9961 caaacatcca caagtcaaag atgatttgaa gaattacctc atccaacttg gaaaagaatt
    10021 gactgagaag gaataaaata aaaagataag gttcaaaaaa tgccttatct tttttcatta
    10081 cacaaatttt ctttcaactt cgtcacattc ccattccctt gtagaaaagc aaaatggcga
    10141 gtcctacgaa caagactacc gctcctaatc tctggctggt gttatacagc cgtttttctc
    10201 ctctaactgg aaagataact gctagaaatg cgccaccaac tgctccaccg atatggcctg
    10261 ctaggctgat ccctggaatc agaacacttc caataatgtt aaccacaaaa agtgtcatat
    10321 aggattggcc caactgctgg atataaggat tacgcgttgc atagcgaaga atgataatcg
    10381 cggcaaatag cccataaaga gaggtagagg cgcctgctgc taaggattta ggactaaata
    10441 caaaaacaaa gagattgccc atcattcctg ataagagata gagaaaaaag aactgcttag
    10501 agccgaaaat ctcctctacc tgccttccaa gataataaag tgaaagcata ttaacaatga
    10561 aatgttccca cccaatatga acaaaaatgg cagacaagag acgccaaacc tgctcgggaa
    10621 agaggcgaat agctggccca tacatggctc caaatcgaaa taatgtatct gccctgtcaa
    10681 agtttccgcc tgcagtgacc aacattagta aaaataccaa ggccgtcact aagaggaaga
    10741 aactcgtcac agggtaacgt ctatcaaaga tttccttcat caattaatac ctcctgaaca
    10801 ggaatatcat ggttttcagg tataaagtcc tgaatttgac aaggatgaac cgtactcaaa
    10861 gtatgaccag aaaaatgttc cagatagcgg tcataataac ctccaccata tccaatccga
    10921 tatccatccg tcgtaaaagc caggccagga acatgaatca aatcaatctg agatacatcc
    10981 accacttcca aatctccctg tggctccagt aaggcaaagg cagtttttac caactgctgc
    11041 agatcataga ctacaaagtc catgcgcccc ttgggataag ttttgggtat taaaaccttc
    11101 ttgccgtcct tcagcgcctg ctcaatcagt tcccgcgttt gaaactcatg agaaaaagag
    11161 aggtaggttg cgatgacctt ggcttcttga taaaaggggt gttgtaaaat tcgctcggtt
    11221 aaagcttggt ctatagcctg tttttgttct tgagataaag ccttcatttc atgcaagact
    11281 tgcttgcgta attccgattt catagacaag ccctctattc tgctgccttc tttttcagga
    11341 aactagacac cgcagccacc ccaatagcta agacttcttc cttaggactc atttgagggt
    11401 gatgaagagc gtagggacta tcgataccta gccaaaacat cacgccatca acctttgaaa
    11461 ggagataacc aaagtcctcg cctgtcatag caggttcgat atcaatcaac tcgattccgt
    11521 ctttctcgtc aaagaagtcc atcagttcac gcgccaaggc tggattgttc tcaacaggta
    11581 ggtatccacc ttgtttgagt tccacttcga cttccatatc aaaggcagct gcaacccctt
    11641 ctgcaactgt ttttaccctc ttttgcacca agagactcat gtcctgtgtc aaggcacgaa
    11701 tagttccatg taaaaaagct gtgtctgtga tgacattgtt ggtggttcca gcttgaaaaa
    11761 cgccgaaggt caccactgct ccctcgattg ggttgacatt gcggctaaca actgactgca
    11821 cttgggtcac aaagtaacta gccgccacca aggcgtcatt ggcttcatga ggaaaagctg
    11881 cgtggccacc tttgcctttg aaacggatct tcacctcgca agttcctgca aagagtgtat
    11941 gagtattagt cgcaatctgg ccgactttca aatctggacg aacatggaga ccatagaatt
    12001 ggtttggcaa ccaatctcca aaagcaccag cctcatacat gagcatacca ccagcttcat
    12061 tttcttcagc aggctgaaat agaaagagca gattattttt aggttgctcc tcaagggcgc
    12121 gctcaagaca gcctaaggca atggtcatat gaaaatcatg gccacaggca tgcatgcgac
    12181 cttggtgttg agaagcaaaa ggtagacctg tttgttcgac gataggcagg ccatcaatat
    12241 ctgtccgcca accaatggtt cgctccggct gacttccctg caggtagacc aaaatccctg
    12301 tccgccaagt acgaatttga acaaaatcct tgcccgtagt caatttctca atcacatcca
    12361 gcaaataagc ctgagtcttg aactcctcca agccaatctc tggtatctgg tgtaaatctc
    12421 gtctagtctg aatcaaatct aacatctatc tgtcctccga tatagcagaa agaggctgga
    12481 aaaagggttc cgcctctttt ttacttttac aattacaagg tacgaagcgc atcctctagc
    12541 gctgtttttt gttgagtttg ggcatcaatt tctttgatga tacgagctgg aacacctgct
    12601 actaccacgt tttctgggac atcttgggta acaatagctc ctgctgcgac aactgaacca
    12661 ctaccgattt ggactccttc gataaccact gcattagcac cgataagaac attgtctccg
    12721 acacggactg gttcagcact agctggctca atcacacctg ccaaaactgc acctgcacca
    12781 acgtggctat tttttccaac gatggcacgg ccaccaagga tggcacccat gtcaatcatg
    12841 gttccagcac cgatttcagc accgatattg ataacagctc ccatcatgat aacagcattg
    12901 tcaccaattt ccacctggtc acggataata gcacctggct cgatacgagc gttgatagca
    12961 cgcttatcta gcaaaggaac tgcagaatta cgagcatctt gctcgacaac ataatcttga
    13021 ttttctacca aaccttcaag aagcggagcc acgtccttcc agtctccgaa taggacattt
    13081 cctagtttga caacagagct aggcacagca gttgcgagtt gcccctcaaa ggttactttg
    13141 acactggttt tcttttcagc attggcgata aattggataa tttcttgagc gttcattttt
    13201 gtagcagtca taggtgcctc ctggttcgtt ataatgatac ctattctacc aaaaaaggcc
    13261 tcaaatttga aacctttttg tctgttttta ggtatgattt tttagggatg tgagataaaa
    13321 cgtgctgtcg gtaaaagcaa gcccctaccg atacaaccta aaaacactct tcacaactat
    13381 ctccccgtgt tttattgact attctagtat agcacacttt tagaattaag aaaagacttt
    13441 ttatctactt tctttcgctt cttctataga caaaaatatc atgggtaaaa taatcaaggc
    13501 tatagctaga aggagggacc aatccactac taatcctaag aacaaaacac tcaagagagc
    13561 agaagagaga ggttcactgg cactgataac ggaaaccacc aaaggagaaa ccaaggacac
    13621 agccttcatg gaaatgaaaa aagcaaaagc cgttccaaag aaagcgataa tgaggcaaat
    13681 caagatactc caaatatcaa gagtaaagga aagctgataa accggcgaga ggacattgct
    13741 aaacaaacct gccaaaatca tcccccaccc aaccgtagga acaaaaccat aacgcttagc
    13801 aaaaggttgg ggcaagataa cattaaacat aacacccatg gcactcagca aacctgttat
    13861 aagagctagc ggcgtcatgg ataactgaga gaggtctccc tttgtcgcca tcaagcaaac
    13921 acccagcatg gcaaccaaaa catagaaaac agcgcttttt gacgctcgtt tttgataaac
    13981 caagcgattg taaaagagga taaagacagg gctaataaac tgtaaaatag ttgctgtcgt
    14041 agcatttgag tattctacac agagatagaa aaaatactga actgaaaaaa tccccaaaat
    14101 agcataggct aaaaagggca ggtaattttt cttgtctcgc caaatatcta gcacttgcga
    14161 ttttaattgt attgcagacc aaatgagtac aagactccct gccagtgtca aacgcataga
    14221 ggtaatccag cccgaagaca cctgataatg agtaaagaag tactctccta aaattccaca
    14281 gattccccat attaagccgg ataggagcga ataaattttt ccgttaacaa tctttttctg
    14341 atactgattc atacccttat tgtaacacga aaggaaaaaa gtggcaatcc attgattggc
    14401 cacttcattt agagaattat cgtctcgccc ttgaagaaga aggtcgtgta gtacttgagt
    14461 tactgctatc gctagaacta ctacttgaac tgctggagct ggatggagtt ggtagactcc
    14521 ccacaatact agaccaagca ttctgataat ccgcatcact tccgccaata gcaaagcgat
    14581 aacttgtcgc tggcgctcct gacttattag cccaatagct ggtaacagtc gaacctgtga
    14641 cctctacttc ttttccttca acagaaacct tccctggttt ttgacctgtt gatttcaaga
    14701 cttccgattt cactacacta ggaactaaag caaagcgctc gttcccccaa atgcttgggg
    14761 aagcttgctg aatcgcattt actagatgag ccatgtaatt agagttatta gaataacctg
    14821 ctctacgtga caatgaatga ttatcatcat gcccaatcca gccacctagg gttaatctag
    14881 gtgtcgaaag catgagccac atattttcgt cttggttggt tgtaccagtc ttcccaatcc
    14941 aatctgcatt agccagagta ggatttaaag aagtcaggtt agacttgaag gttgttgtca
    15001 cacgagagga tagaacttct cgtagcaatc cctgcataat cgtcgcagta gcttttgaat
    15061 agacttgaac cggtttatcc tgatactcat acaccactct accatctgct gcttcaatct
    15121 ttgaaatcac atgcttctga tgataaactc cattattagc taaggtctga tagccattgg
    15181 tatgctgggc aactgtgact tcaataccac cacccattgg caagctctca ataccgtact
    15241 caggaatctc gtaacccatc ttttccatat aacccttgac atcaacaccc ttttcacgga
    15301 gcatacgata ggtccagtaa gcagggatat tccatgaata gttcagagct tctcccaagg
    15361 tcatcattcc tgttcccttg ctattagcat acataatcgg attgccatta gcaaagtttg
    15421 ttggatagtt agatagaatc gtttcacttc ccatcaagcc ctgatcaata gcaataccgt
    15481 aggccagcaa gggcttggta gtagaagctg gcgaacgttt ggtatcaaag gcatgattat
    15541 tttgattttc ttgataatta cgaccaccta caaagcctag aatagcacct gtttggttgt
    15601 ccatcaagac attccctact tctacacgac ctgttccatc gtctaaaaga tagccataat
    15661 cagcaaccgc actttgcatg gcagaatgaa ttttctgatc tatggtagta gtaatcttat
    15721 aaccaccatt ttcaatttcc ttggctgcca aatctcgata aaacttctga gttgcctcat
    15781 ttttcaactc cttagcggag acattgtctc tctgagctag atagtcatac atacgttctt
    15841 gagcttctgc caaagttgta aagtataaat agtctcgtga aattcctgta acagtgcccg
    15901 atggtaaaaa gtcctgttta aggtcataat ccttgtactg agaatactcg tctttgctta
    15961 atgcacctgt acgatacata ctgtaaagaa ctgccttagc ccgtcttaag ccaatttcta
    16021 ggtcttcatc actcttcaac tccccagtat tttcataagg agagtaagta atgggactct
    16081 gtggaagtcc tgctaaaaat gctgcttgag gaacagtcaa ctgactggca tctacaccga
    16141 aaattccctc agctgcttgc cgagcccctg caatattctg tcccttatta tttcggccaa
    16201 agggagccac attgagatag gtcgttaaaa tctcatcttt attcatggcg cgttccaagg
    16261 caagagcatc cacaatctct gccgccttac gagccaaggt cggcgcatcc ccaaccacct
    16321 gctgtttaat tagttgctgg gtcaaggttg aacccccact agaggaaccc aaacctacaa
    16381 atttccccaa ggtcgcacga atcaccgcct tgggtactac acccttatgt tctttaaagt
    16441 gttcatcttc tgtcgcaatg atagccttct tcagattttc cgaaatttgc tcagatgaga
    16501 tagaagtgcg caacaaatca ctctctatgg aagcaatcac cgtcccgtcc gaataggtaa
    16561 tctctgaaat agaagagatg tccttgacct gattcaccaa ttcttctgtc tgaggcaccc
    16621 gaaccttgtc aaataaggcc actccgtacc ccaaagcaat cccagctccc aacattcctc
    16681 ctagaaaacc gagtacaaag agtaagttaa ataaggcttt tatactcagt aaaatagctg
    16741 ggaaaatggc tgacttatct aaggttttag attttttggt acttgaacct ttcttgccag
    16801 gtctagctga ttttttattt ttttgttttt gctggaaaaa ttccagcatt tttcgtttta
    16861 attcatttaa ttgattttgc atggatttcc tcactctatc tattatacca caaaagggaa
    16921 attttcaata aaatagccac tttcttccct attctgctag gctattgccc aagtttgtga
    16981 tacaataggt agaaacaata attttaaaaa ggagaaaaga cacatgcaca tttttgatga
    17041 gctaaaagag cgtggtttga tatttcaaac gactgatgaa gaagctttgc gtaaagccct
    17101 agaagaaggt caagtttctt attatactgg ctacgatcca actgctgaca gccttcacct
    17161 aggccacctt gtcgcaatct tgacaagtcg tcgcttgcaa ctagcaggtc acaaacctta
    17221 tgcgctcgtt ggcggtgcta caggtctcat cggagatccg tccttcaaag atgctgaacg
    17281 tagtctccaa acaaaagaca cagtagatgg ctgggtcaag tctatccaag gacaactttc
    17341 tcgttttctt gactttgaaa atggcgaaaa caaggctgtc atggtcaaca actacgactg
    17401 gtttggcagc atcagcttca ttgacttcct ccgtgatatt ggaaaatact tcacggtcaa
    17461 ctacatgatg agtaaggaat ctgttaaaaa acggatcgaa acaggaattt cttacactga
    17521 gttcgcttac caaatcatgc aagggtacga cttcttcgtc cttaaccaag accataatgt
    17581 cactcttcaa atcggtggtt ctgaccagtg gggaaatatg acagctggta ccgaattgct
    17641 tcgtcgtaag gcggacaaga ctggtcacgt tatcactgtt ccactaatca cagatgcaac
    17701 tggtaagaaa tttggtaaat cagaaggaaa tgccgtctgg ctcaatcccg aaaagacttc
    17761 tccatacgaa atgtaccaat tctggatgaa cgtgatggac gctgacgctg ttcgcttctt
    17821 gaaaatcttt actttcttgt cacttgatga gattgaagat attcgtaaac aatttgaagc
    17881 agcgccacac gaacgcttgg ctcaaaaagt cttggctcgt gaagttgtta cacttgttca
    17941 cggagaagaa gcctacaaag aagcacttaa catcactgag caactctttg caggaaacat
    18001 caaaaacctt tctgtcaaag agctcaaaca aggacttcgt ggtgtgccaa actaccaagt
    18061 acaggcagac gaacataaca atatcgtgga actgctcgtc tcatctggta tagttaactc
    18121 aaaacgccaa gcccgtgaag acgtccaaaa cggagccatc tacgtaaacg gcgaccgcat
    18181 ccaagacctt gactatgtct tgagtgacgc tgataagtta gaaaatgaac tgactgttat
    18241 ccgtcgtggg aagaaaaaat actttgtatt gacttactaa actattcaac atttatctat
    18301 aaacaaagga gttaacctcg agaaaggtaa ctcctttttg ctgttaataa ctctcatcta
    18361 tctattttta atagacaagc tacgcaagac aatgcgcaag gttgttagat tatgtaagat
    18421 agagagattt gaaggactga accaattaaa taagccaaag ccaatcaaac tactatttac
    18481 gacaacggta tcttgaatat ttttcttgat gagtgtttgc aaagatgatg ataacgaatc
    18541 caactcttgg aagaaatcca aacgattatc taacaataag atatcactca tctgcttaga
    18601 aatatctgca ctctcattca tcaccacacc gatatctgat agagttaaag ccgctgagtc
    18661 attcaatcca tctccaacca tcaaaatagt gtgacctgct ttctgcagtt tctctactaa
    18721 ctcaaatttc ccatcaggtt tcaagtctgt atagacctga tcaaagggca aatctttgac
    18781 taattcctct gtcctaatca aggtgtctcc tgttgccaga atcaattttt tcccctgtgc
    18841 cttaagttta tccaaggctg tttttgcttc ttttctcaaa ggagtatgaa tgcagaacat
    18901 tccaatcaat tcattttgat aagccaagaa taagagattg tagtgactct tgtactcttc
    18961 aattaaagca ttttgttctg aactgatatg aatctgctca tcctgcatca agacataatt
    19021 cccaataaga actggttggc catctatatg agatttgatc cccttgcttg cgatatattg
    19081 gagtttccca tgcatttcct catgttcaat tccctctatc tcagcttgct tgacgatggc
    19141 attagcaata ggatgataaa tgtgttcctc aagacaggca ctgattctga gaatatcttc
    19201 ctcactatag tctccaaaag gtaacacctt ttcaactata gaataactag ttgtgattgt
    19261 tcctgtctta tcaaacaaga aagtatcaac ttccagatat ttctccagaa catctccatc
    19321 cttaatcacc atttcacggt tcaacccctc cttgataact gtcaaataag ctacaggagt
    19381 agagattttc aaagcgcagg agaaatcgac caataggaaa gaaatagcct tagaaaaaga
    19441 acctgtcaat aggtaagtca gcccagcccc caagaaatta tatttgacga ctttatccgc
    19501 catcttgatg aaatagcgtt gtttcgtttt cttgttttct tcagatttct tcatcaactc
    19561 aatcagctgt aaaatacggc tgttcatctg attatctgtt acacgaatgc gtaactctcc
    19621 agtttctaat actgtatttg cacaaaccaa atcagactct cttttttcaa ctggaaaact
    19681 ctctcctgtc aaggaacttt cgttgaccat acctaaacct gaaactactt gcccatcaaa
    19741 cagaatttca tttccttgag ataagatcaa gacatctcct atttgaacat cggaactctt
    19801 tatactaaca accgtatcgc cctgtactag gaatacatcg ctctcttttg caagaagact
    19861 ctgttctaaa tctgttgcag tttttttcaa ggaccactga tctaaatgat tccccaaatc
    19921 aagcataaac atgatattgc tagctgtctt ggattggttc ataaacaaag acaataaaat
    19981 agccgaacag tccaagactt ccatagttag ttccttacgc gctagtgttt gataggcttc
    20041 tctaatataa cccaaagcct gataacaagt ccatatatag cgaataggat acggcacaaa
    20101 actacgaaaa agtacacgct taaccgctgc acctgaaaca atagaataag cactctcttc
    20161 tctacgaatg ggaagagtca tcaactcaga aactttccct ttatcaattc tttttaaaaa
    20221 ggcttctgca ttatctaata cagaaaagcc ttcttttatg cgtagagtaa agtgctgttg
    20281 atccatgtaa aactggatag actcaatccc cttttcatct ctcgccaagg aacgaagata
    20341 gtcttgaata tccaaggtaa gtgaaaaaga agatgatagt cggatatgtt ggtatcctct
    20401 atgtagcact ttaaaagaca tattattcac ctataaggct atctaattgc tcttcttttt
    20461 tctcttgctc gtacaaatat ttggcatctt gcaagacatc gtctccatgt tgcttcacaa
    20521 cagaaacaga tgcatctagc tcgtctttca acttgtaagc cttagccaaa gctttagaat
    20581 aacctttttt agcttcctta cttgctaaga ttttcaaacc aagggtacca aatgcgacac
    20641 cacccaaaaa taatgaagat tttttcgcaa cttttgcaac ggttaatact tcttttaaca
    20701 tacttatttc ctccttatca ttattatata gcaatttaga tataaaagca atttcattct
    20761 ataaattgga gaattagttt tatttctact gaatctccca tctacttatt cctaaagttg
    20821 ctttcatttg cctcttttga tacacttaaa ctatgaatac aaatctcaag cccaaacttc
    20881 agcgttttgc ttctgcgact gcctttgcct gtcctatctg tcaagaaaat ctgactctgt
    20941 tagagactaa tttcaagtgc tgcaaccgtc attcttttga cttggcgaaa tttggctatg
    21001 tcaatctagc acctcaaatc aagcaatctg ctaactataa caaggaaaat tttcaaaacc
    21061 gtcaacaaat cctagaagcc ggcttttacc aagctatctt agatgctgta tctgacttgc
    21121 ttgcaagctc aaaaactacc acaacaattt tggatatcgg ttgtggtgaa ggattctatt
    21181 ctcgcaaact acaagaaagt cactctgaaa aaactttcta tgcctttgac atctccaaag
    21241 attcagtcca aatcgctgct aaaagtgaac ccaactgggc agtcaattgg tttgttggcg
    21301 acttggcacg acttcctata aaagacgcta acatggatat tctgcttgat atcttctcac
    21361 ctgccaacta tggagaattt cgtcgcgttt tatccaaaga cggtatcttg ataaaggtta
    21421 tcccaactga aaatcacctc aaagaaatcc gtcaaagagt acaggaccag ctgacaaaca
    21481 aggagtattc taaccaagat atcaaggagc atttccagga acactttacc atcctatcta
    21541 gtcaaactgc ctctctgact aagactatca cagcagaaca actccaagcc ctactcagta
    21601 tgactcctct cctctttcac gttgaccaga gcaagattga ctggagccaa ctgacagaga
    21661 ttaccatcga agcagagatt ttggttggga aagcattcta aactagactt cccaaaggta
    21721 taaaacttac cgaaaatctt caatattata aaaacgcata agaacaggta cacaaacctt
    21781 aatcttatgc gttttgttat agtttccata cacattaagg ggaaatagtt gaaatcagtt
    21841 ctcttaataa ccattgaata ccatatacta catttacccc aaatatgata taggccgtat
    21901 aaatcaagta tttcgatttc tcccgtctca aagaataaat cttgtacaaa atagataaat
    21961 ttaaaataat aaataataga gacaaaatct tcctccaaaa tcaatattaa aagtagccag
    22021 tcaatcatag ttctaatctt tattttcgat tcgaaattac aaacttatca atgaacaata
    22081 agtgatataa ggccagtacc agaccccaaa cgctaccacg aaaagagaat tcttgatgat
    22141 tgagagtaaa caaatcatgg ttaccaatat agaggcaggt caaaataaca aataaaatcc
    22201 aaaataaatc cgtccattta tattttgaaa aatatttttt aacataatag catatttttt
    22261 tgactataat aacagtatat gataaaatgt aagcagatac aaataaaaag gagaaaagct
    22321 catgaacaaa ttaatgaaat ttatttcggt ttttttgacg tcaattgtgt taattgtatc
    22381 agcgattcca agtgtttcag ctgtatacgc ttctgaacaa gtatcacaaa ttgaaacaaa
    22441 tatggaactt caacctgtca cttctctaac agaagaacaa atcaatacac ttgcaaacga
    22501 aatccaatct tttcatccag acgtctcaca acaatggatc aaagaagtaa ttaaccgaca
    22561 attacaaggc gattatacaa tcccacctac atactctcca tttagagcag cttggcaagg
    22621 tattacagtt aatcaaatgg gtgctctatt agatactgca atagctttag cattaggagg
    22681 aactactgca ggccttgcaa atctaattaa agtaaaagga aaacatgcag caaaaagtgc
    22741 tattcgttca gcaatttcta gatatctagg tagttggttt gtaaatgatg ttgctttaga
    22801 attcgctatg aatttattat caccggggat ttatttagca caattatggg ataaaaatga
    22861 tgccattcct aacaacggaa ggattaactt ttaatcatga gatatacaat aaaattaatt
    22921 gggtataacg tattttcgtt gtttatattc tttatcttat caatgttgtt taaagttccc
    22981 tttaggtggt ggatcagcat tgcaatgacg acttcgtcgt acattgtata taattactta
    23041 aagaaaaaga gagaaaagga atgatcttat accagatcat tccttttctg ctttctgtaa
    23101 atccctcgga gtgtgtttgg cgctttgata cgaagtgtca aagctgtata aacgttacta
    23161 tttccaaaaa agtaacagaa aattcctgct ttgtaggact gctttgggtg agtaatagac
    23221 atgtagactc accctatctc ctgatggcga aaagaattta gcaatgatgc aagttgttct
    23281 gaactcgaga aaaaacatgc cgaaatcgaa gaaaagcgtg cagaacttga agcgaagaag
    23341 caagaaatgt tgaagctctt ggataaatag aatttagaaa acagaaaaaa ctaaaaaaaa
    23401 tgtagggttt atttccctac attcttaaaa taacttagta cataaatgac aatgctgcca
    23461 ctgccgtcaa tattgcaaaa actattttcc aaattttttt attttttcca aaaatcttat
    23521 caggtaacaa gcttattaca agaaaggtaa taaacaacac caatttaagt gtgtatatca
    23581 taaaaacacc ttctttccta caattatatt ataatacttt atgtaagcga atataataga
    23641 tgtgaggtaa ccaactacga aaaaatataa ggctgaagac agtaaaaacc agcatttaaa
    23701 gccttcactg tatctaggat ttccctattt ttagacaaga ttgacccaaa tccacagcat
    23761 ttaaaaaagc gaatttcaat tgaaactcgc ttttttacaa gatgtattag tataaatttg
    23821 tatcttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa
    23881 gcaccgcttt gaggttgcag ataaagctga cgtggtttga agagattttc gaagagtatt
    23941 agttcaagtg ccagatgtct tcgttatact gagcgattgt acggtcagat gagaagaatc
    24001 ctgctttaga aatgttaacg atgactttat ccaaccatgc gtcacggtct tcgtagtcag
    24061 caagcatttg ctctttgact ttgatgtagt cttccaaatc aagaagagtc atgaaccagt
    24121 ctttgttgat caattcattg taaagacgtt ccaagcgctc tttgtttcca gctgcaagaa
    24181 ctgcatcact aacgatgaag tcaaccaatg gtttgatagc ttcacgagcg tagaattcgc
    24241 ttgatttgta agctgctttt gcgtaaaggt cgataacagt ttctgaattt tcaccgaaga
    24301 tgtagatgtt ttcttctcca accaactcag cgatttccac gttagcaccg tccatagtac
    24361 caagtgtcaa agctccgttc aacatgaatt tcatgttacc agtacctgaa gcttctttag
    24421 aagcaagtga gatttgttct gagatatcac atgctgggat aaggaaactt gctgcagtaa
    24481 cgttgtagtt ttcaaccata actacttgca agtgtggagc tactgctgga tcgttagcaa
    24541 taacttctga catgcaaagg attaaatgga taatgtcttg agcgattgtg taggctggag
    24601 ctgctttacc accaaagaag attgtgattg gacgagcagg gatgttacca gctttgatgt
    24661 caaggtattt gtggatcacg tacaaagcgt tcatttgttg gcgtttgtac tcgtgaagac
    24721 gtttgatttg gatatcaaag atagaatttg gattgatttc cacaccttgg tgttctttca
    24781 agtgacgagc caatttacgt ttgttgtgag ccttgatgct ttccaatttt tctttgacag
    24841 ctgctttgtc ttcataagac aacagttttt caagctcatc tgcttcatgg tgccaaccat
    24901 ctccaagaat ctcatccaag tagtgagaca atcttgggtt agcatgcata agccaacgac
    24961 ggaaagtgat accgtttgtt ttgttgttga acttttctgg gtaaaggtcg tagaaggctt
    25021 tcaactcaga atttttcaag atttcagtat ggagtgctgc aaccccgtta acactgtatc
    25081 cgtagtggat atccatgtga gccatgtgaa cacgtccgct ctcatcgatg atttgaacag
    25141 ctggatcttt gtactctgcc ttcacacgac ggtccaattc ttcgatgatt ggtaccaagt
    25201 gaggaaccac ttcttgcaag aattcaagag gccatttttc aagcgcttca gcaaggattg
    25261 tgtggttagt gtaggcagtc atgctacgaa caattgagat tgcttcgtca agatcgatac
    25321 cacgtgcagt caaaagacga atcaattcag gaatcaccat tgatgggtga gtatcgttga
    25381 tttggacaac tgcgtagtca gcaaggtcat gcaagttgct tcctttttcg attgcttcgt
    25441 cgatgatcaa ttgcgcaccg tttgaaacca tgaagtattg ttggaagata cggagcaatt
    25501 caccttgacg gtcactatca tctgggtaaa ggaagagagt taagttgcga gcgatatctg
    25561 tcttgtcaaa gttgatacca tctttaataa tagaagaatc aactgaatcc aagtcaaaca
    25621 aacgcaagcg gtttttagtc gctgtttcat aaccagtaac atcaatatcg taaagagttg
    25681 atgtcaaagt aaagtctgca aatggtactt ggtagctacg gcttgagcga accaaccagt
    25741 tttgctctgt caaccatgca tttggaattg tttcttgttg gttgttttta agaacttgtt
    25801 ggaaaagacc aaagtggtag ttaagaccaa caccgtcacc attcaaacca agagtagcaa
    25861 ttgagtcgat aaagcaggca gccaaacgtc ccaaaccacc attaccaaga gatggttcca
    25921 attcaacttc ttcaacttcg atcaagtctt tacctgcagc tgcaagttct tttttaacat
    25981 cgtcgtaaag accaaggtta atcaagttgt ttgacaagag tttaccaatc aagaactcag
    26041 ctgagatgta gtaaactttt ttcttaccag tgttgactgg tttttggctg cttgcaagct
    26101 tgctgtagtt aagaagagca aggtaaagct cttcattgct acattctgca atggttttat
    26161 tgtaacgatt ttgtacaaat tcttgtagtg ataacatgtt tagttgtctc ctgattattg
    26221 tcttatttct ttaaatctac caaattttca ttaattcggc gataaattgt tgtcaagtca
    26281 agcaaacctt cctcgacagc tggtgtcaat tgatcttcag tcatacgcca agaccagttt
    26341 ccaccaaggg tagatgggaa gttcatacga gctgcctcat ccaattctag taaatcttgc
    26401 atagttgcaa ttgccataaa gctaactgat gaaaatactg tacgaagcat agcgtgtacc
    26461 actgtttcgt attctttacg gttcgtgtaa cgagccatgt actcacgagt cgcatcatca
    26521 atctcattac ggtaccaacc aagaaccgta ttgttatcgt gtgttcctgt gtacataact
    26581 gagttagcag gtgccaagtg tgggctatca atgctttcgt cttctgggtt gaaggcaaat
    26641 tgaagaatct tcattcctgg gaagccagta cgttcacgca attcgatcac ttcatctgtc
    26701 atgaagccaa ggtcttctgc gatgatgttt agctcaccaa gttcttcctt aacggctgca
    26761 aaaagcttgt agcctggacc tttcacccac tcaccaggtg ctgctgtatc ggaaccagca
    26821 gggatttccc agtaagattc gaagccacgg aagtggtcga tacgaacgat atcgtagatt
    26881 ttgaagcttt cacgcaagcg ttcaatccac catttgtagc cgtctttgtc cattgcttcc
    26941 cagtcataga ttgggttacc ccaaagctga ccagttacag aaaactcatc tggtgggcat
    27001 cctgcgatac aagtagcctt accattgaca tctgttttga agagatgtgg atttgcccac
    27061 atatcacttg aatcttccgc tacgtagatt ggcatgtccc caacgatttc gatgtggttg
    27121 tcgttagcgt aagctttcaa tttcaaccat tgttggaaga agaagtattg agtcacacgg
    27181 tggtaaacca acttgtctgc caattgctca cgatagcttt caagtgctga agctttacga
    27241 gcacgagcat ctgcatctgg ccattcagtc caagcaagat tgtcaaaata ctctttgata
    27301 gccatatact cagcaaagag ctcaagccat gattggttgt cttgagcaaa tttctcaaaa
    27361 tctttaacat ctccgacttc aaagaaacgt ttcaccgctt tttctaaaag aggacgacgt
    27421 gcatagtaga ttttagcata gtcaacttca gacgcatcgc taccaaagtc aactccttca
    27481 aggtcacttg cttccaacaa accttgctcc accaagatat ctaaatcgat aaaatgagtg
    27541 tttcctgcga aggctgagaa agattggtaa ggagaatccc cgtaactagt tgctcctaat
    27601 ggaaggattt gccagtaacg ttgttttgta cggaccaaga aatcaacgaa gtcgtaagca
    27661 ctttgaccaa atgatccgat tccgtaagct cctggaagag aagagatgtg catcaacaca
    27721 ccactttgac gttttttcat aatagcacct cgtgtgttaa aataatggaa cgttgcgtat
    27781 tttgcagacg caaacgtttg cgttacttat aagtatactc cttttcaagc ataattgcaa
    27841 gcgtttttaa aaaacttttt tgattatttt taaggagact aactcatttt agcaaagata
    27901 acttaaaact atctaatcct aaggtttgac tctcacgaga cagtctacaa agtacaaaac
    27961 ctccttaggg agcttgaatt tatatgtaac aaagcacaaa cgtccataga aaatagatag
    28021 ggattagaac cagggaggta gcccctcctg gtttccctct ttagacagat tccatatatt
    28081 tttattaaaa atactgtatt cttatctatt tcatactttt cttctattaa aatgcaaaat
    28141 tatgctatca aatcaagctt aaaaattttt taaaattttt acaaaaaata cttgcaaccg
    28201 ttttctattt gtgctatact aagctcataa aggaaaacgt ttgcgtttcc ttatcaataa
    28261 aacttgctat tctttgggag gaatacacta tgtcatctaa atttatgaag agcactgcgg
    28321 tgcttggaac tgttacactt gctagcttgc ttttggtagc ttgcggaagc aaaactgctg
    28381 ataagcctgc tgattctggt tcatctgaag tcaaagaact cactgtatat gtagacgagg
    28441 gatataagag ctatattgaa gaggttgcta aagcttatga aaaagaagct ggagtaaaag
    28501 tcactcttaa aactggtgat gctctaggag gtcttgataa actttctctt gacaaccaat
    28561 ctggtaatgt ccctgatgtt atgatggctc catacgaccg tgtaggtagc cttggttctg
    28621 acggacaact ttcagaagtg aaattgagcg atggtgctaa aacagacgac acaactaaat
    28681 ctcttgtaac agctgctaat ggtaaagttt acggtgctcc tgccgttatc gagtcacttg
    28741 ttatgtacta caacaaagac ttggtgaaag atgctccaaa aacatttgct gacttggaaa
    28801 accttgctaa agatagcaaa tacgcattcg ctggtgaaga tggtaaaact actgccttcc
    28861 tagctgactg gacaaacttc tactatacat atggacttct tgccggtaac ggtgcttacg
    28921 tctttggcca aaacggtaaa gacgctaaag acatcggtct tgcaaacgac ggttctatcg
    28981 caggtatcaa ctacgctaaa tcttggtacg aaaaatggcc taaaggtatg caagatacag
    29041 aaggtgctgg aaacttaatc caaactcaat tccaagaagg taaaacagct gctatcatcg
    29101 acggaccttg gaaagctcaa gcctttaaag atgctaaagt aaactacgga gttgcaacta
    29161 tcccaactct tccaaatgga aaagaatatg ctgcattcgg tggtggtaaa gcttgggtca
    29221 ttcctcaagc cgttaagaac cttgaagctt ctcaaaaatt tgtagacttc cttgttgcaa
    29281 ctgaacaaca aaaagtatta tatgataaga ctaacgaaat cccagctaat actgaggctc
    29341 gttcatacgc tgaaggtaaa aacgatgagt tgacaacagc tgttatcaaa cagttcaaga
    29401 acactcaacc actgccaaac atctctcaaa tgtctgcagt ttgggatcca gcgaaaaata
    29461 tgctctttga tgctgtaagt ggtcaaaaag atgctaaaac agctgctaac gatgctgtaa
    29521 cattgatcaa agaaacaatc aaacaaaaat ttggtgaata aaaaatttgt tcaagggggg
    29581 tggaaatcaa atcccccttt gaatttatca atagagacac aaataattta gctttcttat
    29641 aaaaaagtag tatcctatga aaggagttaa tatggaaaag caacaaccta gtaaagcagc
    29701 cctgctgtct atcattcctg ggttaggaca gatttacaat aaacaaaaag ccaaaggttt
    29761 tatcttcctt ggtgtaacca tcgtatttgt cctttacttc ctagcacttg caacccctga
    29821 attgagcaac ctcatcactc ttggtgacaa accaggtcgt gataattccc tctttatgct
    29881 gattcgtggt gccttccatc taatctttgt aatcgtttat gtactctttt atttctcaaa
    29941 tatcaaagat gcacatacga ttgcaaaacg cattaacaat ggaattccag ttccacgcac
    30001 actcaaagac atgatcaaag ggatttatga aaatggcttc ccttacctct tgatcattcc
    30061 atcttatgtt gccatgacct tcgcgattat cttcccagtt atcgtaacct tgatgatcgc
    30121 ctttaccaac tacgacttcc aacacttgcc accaaacaag ttgttggact gggttggttt
    30181 gaccaacttt acaaacattt ggagcttgag taccttccgt tctgcctttg gttctgttct
    30241 ttcttggact atcatttggg ctttggcagc ttctacttta caaatcgtaa ttggtatctt
    30301 cacagctatc attgccaacc aaccatttat caaaggaaaa cgtatctttg gtgttatttt
    30361 ccttcttcct tgggctgtcc cagccttcat cactatcttg acattctcaa acatgtttaa
    30421 cgatagtgtc ggtgctatca acactcaagt attgccaatc ttggctaaat tccttccttt
    30481 ccttgatgga gctcttattc cttggaaaac agacccaact tggactaaga ttgccttgat
    30541 tatgatgcaa ggttggctcg gattcccata catctacgtt ctgaccttgg gtatcttgca
    30601 atctattcct aacgaccttt acgaagcagc ttatattgac ggtgccaacg cttggcaaaa
    30661 attccgcaac atcactttcc caatgatttt ggctgttgcg gcacctactt tgattagcca
    30721 atacaccttc aactttaaca acttctctat catgtacctc ttcaatggtg gaggacctgg
    30781 tagtgtcgga ggtggagctg gttcaaccga tatcttgatc tcatggatct accgtttgac
    30841 aacaggtaca tctcctcaat actcaatggc ggcagctgtt accttgatta tctctatcat
    30901 tgtcatctca atctctatga tcgcattcaa gaaactacac gcatttgata tggaggacgt
    30961 ctaagatgaa taactcaatt aaactcaaac gtagactgac tcaaagcctt acttaccttt
    31021 acctgattgg tctatcaatt gtaattatct atccactgtt gattaccatt atgtcagcct
    31081 ttaaagcagg taacgtctca gcctttaaac tagatactaa tatcgacctc aattttgata
    31141 actttaaagg cctcttcact gaaaccttgt acggtacttg gtacctcaac actttgatta
    31201 tcgccttaat taccatggct gttcaaacaa gtatcatcgt acttgctggt tatgcttaca
    31261 gccgttacaa cttcttggct cgtaaacaaa gtttggtctt cttcttaatc atccaaatgg
    31321 tgccaactat ggccgctttg acagccttct tcgttatggc gcttatgttg aacgccctta
    31381 accacaactg gttcctcatc ttcctctacg ttggtggtgg tatcccgatg aatgcttggc
    31441 tcatgaaagg ctacttcgat acagtgccaa tgtctttaga cgaatctgca aaactagacg
    31501 gtgcaggaca cttccgccgc ttctggcaaa ttgttctacc acttgttcgc ccaatggttg
    31561 ccgtacaagc tctctgggcc ttcatgggac ctttcgggga ctacatcctc tctagtttct
    31621 tgcttcgtga gaaagaatac tttactgttg ccgtaggtct ccaaaccttc gttaacaatg
    31681 cgaaaaactt gaagattgcc tacttctcag caggtgctat cctcatcgcc cttccaatct
    31741 gtattctctt cttcttccta caaaagaact ttgtttcagg acttacaagt ggtggcgaca
    31801 agggataatt tatccccgcc accctttttc attttatact cttcgaaaat ctcttcaaac
    31861 cacgtcagct ttatctccaa cctcaaagtt gtgctttgag caacctgtgg ctagtttgca
    31921 ctttgatttt cattgattat tagcaattgt cactgtaaat aatatccttg tagcaagcaa
    31981 tttttctcct agacttgaaa taaagcgcat ttctctatat aataatactc atatagaaaa
    32041 caccttttag aaagatacct atgcttccat atccattttc ctatttttca agtatttggg
    32101 ggtttcgtaa gcccctgtcc aaacgtttcg agctcaactg gtttcaactt ctctttacca
    32161 gtatcttcct tatcagcttg tctatggtac ccattgctat ccaaaacagc tcccaggaga
    32221 cctatccgct agaaactttt atcgataatg tctatgaacc tctgacagat aaggttgtcc
    32281 aggatctctc tgaacatgct acaattgtcg atggcacatt aacttatact ggaacagcta
    32341 gtcaagcccc ttctgttgtg attggtccaa gtcaaatcaa ggaattacct aaggacttgc
    32401 aactgcattt cgatacaaat gaactagtca tcagcaagga aagcaaggaa ctgacccgca
    32461 tctcttaccg agccattcag actgagagtt tcaaaagcaa agacagcttg acccaagcaa
    32521 tttctaaaga ctggtaccaa caaaatcgtg tctatatcag cctcttccta gttctcggtg
    32581 cgagcttcct ctttggtttg aatttcttta tcgtctctct aggagctagt cttctccttt
    32641 atatcactaa gaaatcacgc ctcttttcat ttagaacctt taaagagtgc tatcacttta
    32701 tcttgaactg tttaggattg ccgactctga ttacacttat tttgggatta tttggccaaa
    32761 atatgacaac cctgattact gtacaaaata ttctttttgt tctgtatctg gtcactatct
    32821 tttataaaac acatttccgt gatccaaatt accataaata ggagattttt atgcccgtta
    32881 cgattaaaga cgtggccaag gctgctggtg tttcgccttc aaccgtaacc cgtgttattc
    32941 aaaataaatc aaccattagc gacgaaacaa aaaaacgcgt tcgcaaagct atgaaggaac
    33001 tcaactacca cccaaacctc aacgctcgta gcttggtaag cagctatact caggttatcg
    33061 gattagttct tcctgatgac tcagacgcct tctaccagaa tcctttcttt ccatcggttc
    33121 tacgtggcat ctctcaagtc gcatctgaaa accactatgc cattcagata gcaacaggga
    33181 aagatgagaa ggagcgtctc aacgctattt cacaaatggt ctacggcaag cgtgtagatg
    33241 ggctaatctt tctctatgcc caagaagaag accctctcgt aaaactcgtc gcagaagaac
    33301 agttcccctt ccttatccta ggtaaatctc tatctccttt catcccactt gtcgacaacg
    33361 acaatgttca agctggtttt gatgcgactg aatatttcat caaaaaaggc tgcaaacgca
    33421 ttgcctttat cggaggaagt aaaaagctct tcgtgaccaa agaccgttta acaggctatg
    33481 aacaggcgct taaacattac aaacttacca ctgacaacaa tcgcatctac tttgccgacg
    33541 agtttctgga agaaaagggc tataaattta gcaagcgatt attcaagcac gatccacaaa
    33601 ttgatgctat catcacaacc gatagcctcc tagctgaagg tgtttgtaac tatattgcca
    33661 aacaccagct ggatgtccct gttctcagct ttgactcggt taatcccaag ctcaacttgg
    33721 cagcctatgt cgatatcaat agtttagagc ttggtcgtgt ttcccttgaa actattctcc
    33781 agattattaa tgataataaa aacaataaac aaatttgtta ccgtcaattg atcgcccaca
    33841 aaattatcga aaaataagag actgggcaaa aagtcgttaa aagcaaaaac gcatactatc
    33901 aggtattgaa aaaacttgat actatgcgtt ttattgtggg aagatttact tccttttctt
    33961 ctgaaattga gttgttaccc aagatctttt tatactcaat aaaaatcaaa gtgcaaacta
    34021 ggaagctagc cgcaggttgc tcaaaacact gttttgaggt tgtggataga actgacgaag
    34081 tcagctcaaa acatggtttt gaggttgcag atagaactga cgaagtcagt aacataccta
    34141 cggcaaggcg acgctgacgt ggtttgaaga gattttcgaa gagtattaat cactaattat
    34201 ctatctcaac aaatcttcct agaatatgaa cattttccga gacagagaca aaggagcttg
    34261 gatccacttg tgtcataatc tgtttaaatt cattaaactc tgcacgtgta atgacagtga
    34321 ttaaaactgc ctttctctcg tgattatagg ttccttctgc atcgtggatc atggttgctc
    34381 cgcggtgcaa ttttttatgg attttttcaa ttaccttctc tggatgattt gtcacaatca
    34441 tggcctgcat acgcttttgc ttagtaaaga ctgcgtctgt cacacggcta gagacaaaga
    34501 tggtaatcat agaataaaga gcgtatttcc aaccaaaggt caaacctgct atcagcatga
    34561 tagttccatt taccaagaaa gaaatactac cgacattctt acccgttttc ttgcgaatag
    34621 tcaggctgac gatatccgtc ccaccactgg agatattgtt tcgaagagca aaaccaatcc
    34681 ccaaacccat aacaacaccc ccaaaaaggg aattgataat gggatcctcc gtcaaggttg
    34741 ccacagggac aaactggata aagaaggaac tcatagatac cgtgataaag gtaaagacgg
    34801 tgaacttatg gccaatctga taccaagcta agaccatcaa agggaagtta atggcgtaga
    34861 agcttagcga aatcggaata tgaaaaccaa accagtgatt actcaaggca gagataatct
    34921 gtgccagacc tgttgcacca ctcgaataca catgccctgg ttggaaaaag aaattaactg
    34981 ctactgctga taaaaaacca tagaccagag aggccgaaat cttctcatca tacttttctc
    35041 gagagatact ttgtaagaca cgtaaaattt ttatctgata agcaaagcgg cgcagataat
    35101 agcgccaccg cttaattcgt tttgtttgtt tcatcttctt ctacttgtaa gctgagttcc
    35161 tctagttgtt tgagagcgac tgttgatgga gcttgtgtca ttggatcagt tgccttgttg
    35221 ttcttaggaa aggcaatgac ttcacggata ttttcttctc cagcaagcaa catgacaaaa
    35281 cggtcaagcc cgatagccaa accaccgtgt ggtgggaaac catagtccat ggcttcaaga
    35341 aggaaaccaa actggtcatt ggcttcttca gctgagaaac caagagcctt gaacatgcgt
    35401 tcttgaaggt ctttttggtt gatacgaagg ctaccaccac caagctcata accgttcaag
    35461 acgatatcgt aagcaatggc acgaacctta gccaaatcac cttctaattc gtgagcagtc
    35521 tcttcctgtg gaagtgtgaa tggatggtgg gcgctcatgt agcggccttc ttcttcagac
    35581 cattcaaaca tcggccagtc aaccacccaa aggaagttga acttatcatt atcaatcaag
    35641 ccaagctctt tagcaatacg tccacgaagg gcacccagtg ttgcattagc cacttcaagc
    35701 gtatccgcca caaagagaac caagtcctta tcttcaagag caagcgctgt tgtcaattct
    35761 tcttggatac cagtcaagaa cttggcaact ggtccgttta attctccatc aaccaccttg
    35821 acccaagcaa gacctttggc accatactgt ttggctactt ccgtcatctt gtcgatgtct
    35881 ttacgtgaat agttgtccgc agctcctttg accacaatcg cttttacagc aagtgcttct
    35941 gaaaagactt taaagtctac acctttgacc acttctgtca agtcctgaag caacatgtca
    36001 aaacgagtat ctggcttgtc agaaccgtaa agagccatag catcatcgta tttcatacga
    36061 gggaacggta gcgttacttc gatgcctttt gtttccttca tcacacgcgc gatcaagcct
    36121 tctgtaatat cttggatttc ttgctcagta aggaaggacg tttccaagtc gacctgagta
    36181 aattcaggct ggcggtctcc acgcaagtcc tcgtcacgga aacatttaac gatttggtag
    36241 taacggtcaa aaccagcatt catcaagagc tgtttcgtga tttgtggact ttgaggaaga
    36301 gcgtaaaaat gccccttatt aacacgagac ggcactaaat aatcacgcgc cccttcaggc
    36361 gttgacttag aaaggaatgg tgtctccacg tcgataaact ccaactcatc caagtagttg
    36421 cggatagagt gggtcacctt ggcacgaagt ttaagatttt ccaacatttc tggacgacga
    36481 aggtcaaggt aacggtaacg caaacgtgta tcgtcatttg cctcaatgcc atccttaatc
    36541 tcaaatggtg ttgtcttagc tgtgttaagc acaataagag ctgtcacgtt taactcaacc
    36601 gcaccagttg gcaacttatc attggcttgc tcacgcgcag cgacctgacc agtcacctca
    36661 ataacaaatt cgctacgaag gctttcagct gttgccataa cctctgcaga tactttttca
    36721 gggttgataa ccaactgcat gattccttca cggtcacgaa gatcgataaa gatcaaacca
    36781 ccaaggtcac gacgacggcc aacccatcct ttcaaggtta tttcttgtcc gatgtgttcc
    36841 tcacgaacac gaccagcata catactacgt ttcattattt ctctcctctt ttattctgtt
    36901 actattttac cataaaagcg caggctcttc atgaaaatca tcagaaaagt ttgccagtct
    36961 ttaaaagtca ggtgaaagcc ctaaaaatta gcgctaatgc tcttcgaaaa tctcttcaaa
    37021 ccacgtcagc gtcgccttac cgt
//
LOCUS       DBJKQU010000014        36095 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.014, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000014 DBJKQU010000000
VERSION     DBJKQU010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.014"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..867
                     /locus_tag="ACSUUC_000823"
     CDS             <1..867
                     /locus_tag="ACSUUC_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HHQ8054066.1"
                     /translation="IVKAWQKQGKVVAMTGDGVNDAPALKTADIGIGMGITGTEVSKG
                     ASDMILADDNFATIIVAVEEGRKVFSNIQKTIQYLLSANTAEVLTIFLSTLFGWDVLQ
                     PVHLLWINLVTDTFPAIALGVEPAEPGVMNHKPRGRKASFFSGGVLSSIIYQGVLQAA
                     LVMSVYGLAIAYPVHVGDNHAIHADALTMAFATLGLIQLFHAYNVKSVYQSILTVGPF
                     KSKTFNWSILVSFILLMATIVVEPLEGIFHVTKLDLSQWGIVMAGSFSMIIIVEIVKF
                     IQRKLGFDKNAI"
     gene            880..1671
                     /gene="yghU"
                     /locus_tag="ACSUUC_000824"
     CDS             880..1671
                     /gene="yghU"
                     /locus_tag="ACSUUC_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HHQ8054067.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            1787..2197
                     /locus_tag="ACSUUC_000825"
     CDS             1787..2197
                     /locus_tag="ACSUUC_000825"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HHQ8054068.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            2209..3804
                     /locus_tag="ACSUUC_000826"
     CDS             2209..3804
                     /locus_tag="ACSUUC_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054069.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRVYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            3971..4135
                     /locus_tag="ACSUUC_000827"
     CDS             3971..4135
                     /locus_tag="ACSUUC_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HHQ8054070.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            4214..4942
                     /gene="yaaA"
                     /locus_tag="ACSUUC_000828"
     CDS             4214..4942
                     /gene="yaaA"
                     /locus_tag="ACSUUC_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HHQ8054071.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(5220..5768)
                     /locus_tag="ACSUUC_000829"
     CDS             complement(5220..5768)
                     /locus_tag="ACSUUC_000829"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase [NAD(P)H] activity
                     [Evidence IEA];
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HHQ8054072.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            6089..6577
                     /locus_tag="ACSUUC_000830"
     CDS             6089..6577
                     /locus_tag="ACSUUC_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HHQ8054073.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEKADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            6574..7761
                     /locus_tag="ACSUUC_000831"
     CDS             6574..7761
                     /locus_tag="ACSUUC_000831"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHQ8054074.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            7754..8119
                     /locus_tag="ACSUUC_000832"
     CDS             7754..8119
                     /locus_tag="ACSUUC_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHQ8054075.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            8138..9481
                     /gene="asnS"
                     /locus_tag="ACSUUC_000833"
     CDS             8138..9481
                     /gene="asnS"
                     /locus_tag="ACSUUC_000833"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HHQ8054076.1"
                     /translation="MTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTAF
                     FQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITDI
                     EVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGFM
                     KFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRAE
                     KSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTEL
                     LKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPTF
                     VMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDELG
                     MDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            9634..9924
                     /gene="rpsF"
                     /locus_tag="ACSUUC_000834"
     CDS             9634..9924
                     /gene="rpsF"
                     /locus_tag="ACSUUC_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HHQ8054077.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            9936..10406
                     /gene="ssbA"
                     /locus_tag="ACSUUC_000835"
     CDS             9936..10406
                     /gene="ssbA"
                     /locus_tag="ACSUUC_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HHQ8054078.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            10438..10677
                     /gene="rpsR"
                     /locus_tag="ACSUUC_000836"
     CDS             10438..10677
                     /gene="rpsR"
                     /locus_tag="ACSUUC_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HHQ8054079.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            10972..12372
                     /locus_tag="ACSUUC_000837"
     CDS             10972..12372
                     /locus_tag="ACSUUC_000837"
                     /EC_number="3.1.3.-"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HHQ8054080.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILIGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            12374..12733
                     /locus_tag="ACSUUC_000838"
     CDS             12374..12733
                     /locus_tag="ACSUUC_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HHQ8054081.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            12787..13536
                     /locus_tag="ACSUUC_000839"
     CDS             12787..13536
                     /locus_tag="ACSUUC_000839"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HHQ8054082.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            13526..13825
                     /locus_tag="ACSUUC_000840"
     CDS             13526..13825
                     /locus_tag="ACSUUC_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HHQ8054083.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGRGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            13896..14831
                     /locus_tag="ACSUUC_000841"
     CDS             13896..14831
                     /locus_tag="ACSUUC_000841"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HHQ8054084.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            14917..15429
                     /locus_tag="ACSUUC_000842"
     CDS             14917..15429
                     /locus_tag="ACSUUC_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HHQ8054085.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            15413..16062
                     /locus_tag="ACSUUC_000843"
                     /pseudo
     CDS             15413..16062
                     /locus_tag="ACSUUC_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            16163..16360
                     /locus_tag="ACSUUC_000844"
     CDS             16163..16360
                     /locus_tag="ACSUUC_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HHQ8054086.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(16403..17848)
                     /locus_tag="ACSUUC_000845"
     CDS             complement(16403..17848)
                     /locus_tag="ACSUUC_000845"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HHQ8054087.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLREQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISNYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            17954..19576
                     /locus_tag="ACSUUC_000846"
     CDS             17954..19576
                     /locus_tag="ACSUUC_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative polysaccharide biosynthesis protein"
                     /protein_id="HHQ8054088.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            19779..21737
                     /locus_tag="ACSUUC_000847"
     CDS             19779..21737
                     /locus_tag="ACSUUC_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HHQ8054089.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     AYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            21909..22109
                     /locus_tag="ACSUUC_000848"
     CDS             21909..22109
                     /locus_tag="ACSUUC_000848"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054090.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSYWSSLVFFYWLLSV"
     gene            22078..22991
                     /locus_tag="ACSUUC_000849"
                     /pseudo
     CDS             22078..22991
                     /locus_tag="ACSUUC_000849"
                     /inference="COORDINATES: protein motif:HMM:NF012869.6"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            22985..23572
                     /locus_tag="ACSUUC_000850"
     CDS             22985..23572
                     /locus_tag="ACSUUC_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHQ8054091.1"
                     /translation="MLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSG
                     SIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRL
                     QIARTYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDC
                     IFFLEEGKITGSGTHKELLENHERYACFVQEQMIE"
     gene            23729..24823
                     /locus_tag="ACSUUC_000851"
     CDS             23729..24823
                     /locus_tag="ACSUUC_000851"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HHQ8054092.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            24831..25997
                     /locus_tag="ACSUUC_000852"
     CDS             24831..25997
                     /locus_tag="ACSUUC_000852"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HHQ8054093.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQIYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            26090..29188
                     /locus_tag="ACSUUC_000853"
     CDS             26090..29188
                     /locus_tag="ACSUUC_000853"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HHQ8054094.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQVLVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            29236..29853
                     /locus_tag="ACSUUC_000854"
     CDS             29236..29853
                     /locus_tag="ACSUUC_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HHQ8054095.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            29864..31198
                     /gene="murC"
                     /locus_tag="ACSUUC_000855"
     CDS             29864..31198
                     /gene="murC"
                     /locus_tag="ACSUUC_000855"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HHQ8054096.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            31208..31672
                     /locus_tag="ACSUUC_000856"
     CDS             31208..31672
                     /locus_tag="ACSUUC_000856"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8054097.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDCKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            31669..32163
                     /locus_tag="ACSUUC_000857"
     CDS             31669..32163
                     /locus_tag="ACSUUC_000857"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8054098.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            32244..33899
                     /gene="mltG"
                     /locus_tag="ACSUUC_000858"
     CDS             32244..33899
                     /gene="mltG"
                     /locus_tag="ACSUUC_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HHQ8054099.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            33970..34452
                     /gene="greA"
                     /locus_tag="ACSUUC_000859"
     CDS             33970..34452
                     /gene="greA"
                     /locus_tag="ACSUUC_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HHQ8054100.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            34825..35223
                     /locus_tag="ACSUUC_000860"
     CDS             34825..35223
                     /locus_tag="ACSUUC_000860"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8054101.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            35672..36095
                     /locus_tag="ACSUUC_000861"
                     /pseudo
     CDS             35672..36095
                     /locus_tag="ACSUUC_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT        10843 a         6733 c         8089 g        10430 t
ORIGIN      
        1 atcgtcaagg cttggcaaaa acaaggtaag gtcgttgcca tgacaggtga cggtgtcaat
       61 gatgccccag ctctgaaaac agcagacatc ggtatcggta tgggaatcac tggtacagag
      121 gtttctaagg gggcttctga tatgattctt gcagatgata actttgcgac tattatcgtc
      181 gcagtggaag aaggacgtaa ggtcttctca aatattcaaa agactattca gtacctactt
      241 tctgccaata ctgctgaagt attaaccatc ttcctatcaa ccttgtttgg ttgggacgtc
      301 ttgcagccag ttcatctttt gtggattaac ttggtaacgg ataccttccc agcaattgca
      361 ctaggtgttg aacctgcgga acctggtgtc atgaatcata aaccacgtgg acgcaaggca
      421 agcttcttct caggtggtgt tttgagttct atcatttatc aaggtgtact ccaagcagct
      481 cttgttatga gtgtttatgg ccttgcgatt gcttacccag ttcatgtggg tgacaatcat
      541 gctattcatg cagatgccct aacgatggcc tttgcaaccc ttggtttgat tcagctcttc
      601 catgcctaca atgtcaagtc tgtctaccaa tccatcttga cagttggccc attcaagtct
      661 aagaccttta actggtccat cttggtatcc tttatccttc tcatggcaac aatcgttgta
      721 gaaccgcttg aaggaatctt ccacgtaacc aaactagact tgtcacaatg gggaattgtt
      781 atggctggaa gcttctcaat gattatcatc gtcgaaatcg ttaagtttat tcaacgcaaa
      841 ctcggttttg acaagaatgc gatttaaggg aggtttcgga tgtcagcata tcaattaccg
      901 accgtatggc aggatgaagc tagtaatcaa ggagctttta cggggttaaa cagaccaaca
      961 gcaggtgccc gtttcgaaca aaacttgcca aaaggagaac aagcttttca gctttattca
     1021 ctgggaacac caaatggtgt gaaggttact atcttattgg aagaattact agaagctggt
     1081 tttaaggaag cggcttacga cttgtataag attgctatca tggatgggga tcaattcggc
     1141 tcagactttg tgaagctcaa tccaaattcc aagattccag ccttattgga ccagtcaggt
     1201 actgaaaacg taagagtctt tgagtctgct catattcttc tttaccttgc tgagaaattt
     1261 ggagcctttt taccaagtaa tcctgtggaa aaggtagaag ttttgaattg gctattctgg
     1321 caagcaggtg cagcaccttt tctaggtggg ggatttggac atttcttcaa ttatgctcct
     1381 gaaaaattgg aatatcctat taaccgtttt acgatggaag tgaaacgcca gttggattta
     1441 ttggataagg aattggctca gaaaccttat attgcaggca atgactatac gattgcagat
     1501 attgctatct ggtcttggta tggacagtta gttcaaggaa atctttacca aggttctgca
     1561 aaatttttgg atgcctcaag ttatcaaaat ctagtaaaat gggcagaaaa aattgccaat
     1621 cgtccagctg ttaagcgtgg attggaagta acttatacag aaattaaata gcaaaaaagt
     1681 catcttcgga tggctttttg ctacagttga gggaaagggt ttgcagttat cggcttttgt
     1741 gctataattg ctataatata gtaaaaagca agaggagtgt gaggaagtgg aaaagaaaat
     1801 tgtgaaggat atcttatttt tatctcaagt gtctcagccg gcaagtcagg aggaccttta
     1861 tcttgccaga gatttgcagg atacactctt agcaaatcgt gatacctgtg ttggtctagc
     1921 tgccaatatg attggggtgc agaagcgcgt gattatcttt aatcttggct tggttcccgt
     1981 ggtcatgttt aacccagtgc ttctgtcctt tgaaggatct tatgaggcag aagaaggctg
     2041 tttgtccttg gtaggtgtga gatcaactaa gcgttatgaa accataaggc ttgcctatcg
     2101 tgacagcaag tggcaggaac agaccattac cttgacaggc ttcccagctc agatttgcca
     2161 gcatgagctg gatcacttgg aaggacgaat catttaggag gaaagcaaat gaaacgaata
     2221 gtctttgaac ttatttttat cgcaacgacc tggtatatct ttttaccgcc ccttaacctg
     2281 accagctggg aatttctctt cttcctctgt gggcatttgt tagttgtggc aatcttattt
     2341 ggctttggca aggggataaa ccttgtcaaa acggttcatg tgcgccacgg taaggcggaa
     2401 gctgccttaa atcttgaggg tttcaaaatc aatcggttag ggaaaattct gttagcttcg
     2461 attggaggaa ttcttctctt ggcagctttg gtttccttgg taacttccag catgtttcag
     2521 gctaaaaatt atgccaatgt agtcacggtt acggaaaaag actttactga atttcctagg
     2581 agtgacacca gtaaggttcc tatcctagat agaagtactg ctgaaaaaat tggagaccgc
     2641 tacttgggtt ccctaaccga taaggtgtcg caatacgtag cggcagatac ctatacccaa
     2701 ttgacaattg atgggaaacc ttatcgggtc acaccactag aatatgcaga ccctatcaaa
     2761 tggtttaaca atcaagccaa gggaatcggt gagtatatca aggtggacat ggtaactgga
     2821 aatgcggatt tggtggactt gaagacacca atcaagtatt cagactcgga gtattttaac
     2881 cgtgatgtca aacgtcacct gcgcttgaag tacccgacta aaatctttaa aactccatct
     2941 tttgaggtgg acgatgaggg caatcctttc tatgtagcaa cggtttacca aaagcaattt
     3001 ggacttgcgg ttcctcgtcc tgcttcagtc attatcttgg atgctacaaa tggagaaacc
     3061 aaggaataca gcttatcaga tgttccagaa tgggtggaca gggtctatcc agcagaggaa
     3121 accattgagc aaatcaacta caacggcaag tacaaggacg gtttcttgaa tgccatgatt
     3181 tccaagaaaa atgtgaccca gactaccaag ggctataatt acttgtctat cggtaatgac
     3241 atctatctct acacaggtgt gacgtcggct aatgcggatg agagtaatct tggtttcatc
     3301 cttgaaaata tgcgaacagg agaaatcact aagtatagct tggcttctgc gacagaagaa
     3361 tcagcccgtg aatcagcaga aggtgctgtt caggagaaat cctacaaagc aaccttccca
     3421 atcctcatca acctcaatga caagcctctc tacatcatgg gcttaaagga caatgctggc
     3481 ttggtcaaag agtacgccct ggtagacgca gtcgagtacc aaaatgttat cgttgctact
     3541 acagtggaag agatgctcag caagtatgcc aataaaaacg accttgaaat tgacaatgca
     3601 acgacagaaa gcatcaaggg agtagtagca gacctcaaat cagctgttat caagggagac
     3661 actgtctact tctttaaagt tgatggcaag atatacaagg tcaaggcttc agtatccgat
     3721 gaccttcctt accttgaaaa tggtaaaacc ttcgaaggtc aagtaggaaa agacaattat
     3781 ctcaagacct ttaaagtaca ataatactct tcgaaaatct ctagctctat ctgcaacctc
     3841 aaaacagtgt tttgagcagc ctgcggctag tttcctagtt tgctctttga ttttcattga
     3901 gtataaaaaa ggtttattta ataaatatat gttataataa ggtaaattaa gcctaatgga
     3961 ggacaaagaa atgggttttt atttgatggt tgcttcaatg ctactcggac tgctcgcttt
     4021 gaagataggt ttttctcagt tcaaggagaa aaaagataaa ttcttatcta tcttaacaag
     4081 tttagctggc acagcccttg ttctcgtggc tgtctggtta ggatggccca aataaataga
     4141 aaaacctcgg tcaaaccgag gtttttcaaa tgaatttctt ggttgtggct aaaaaatatg
     4201 ctacactatc aatatgaaaa ttttaatccc aacagcaaaa gaaatgaaca cagacttgcc
     4261 aagtatcgag gcaattcctt taaaaccaga aagtcagacc gtgcttgatg ccttggctct
     4321 ctattctgcc agtcaattgg agagtttcta caaggtatcg gctgagaaag cggcggaaga
     4381 atttcaaaat atccaagctt tgaaaaggca aactgctcaa cactatccag ccttgaaact
     4441 ttttgatggg cttatgtacc gcaacattaa gagagataag ctgaccgagg cggaacaaga
     4501 ttatcttgaa aatcatgtct tcattacctc ggctttgtac ggtgttgttc cagccttgtc
     4561 acccatggct cctcaccgtt tggatttttt gatgaaatta aaagtcgctg gtaagacttt
     4621 gaagagccat tggaaggcag tctatgatga agctctgaag aaggaagaag tgattttctc
     4681 tctcttgtca tcagagtttg agactgtatt ttctaaggaa atcagagcaa agatggtgac
     4741 cttcaaattc atggaggata gaggcggtca gctgaagatt cactcaacta tctccaagaa
     4801 agcgcgcggg gcctttctaa cagctttaat agaaaatcaa gtacaaactg tgggggaagc
     4861 acgtcgcttg aactttgctg gatttgttta ccgagaagat ttgtcacaac cacagggatt
     4921 ggtttttgta aaggaagtat agaaatcaga tattttgtat ttggcaatat gtatcatcag
     4981 ctgttttagt ttataaatga gaaaaaaagc gaacaagcta gtcttctgag tgtcagaaaa
     5041 gtagtcttgt tcgcttttat tatgttatac tcttcgaaaa tctcttcaag ccacgtcagc
     5101 gtcgccttac cgtatatatg tcactgactt cgtcagttct atctacaacc tcaaagcagt
     5161 gctttgagca gcttgcggct agcttcctag tttgcttttt gatttttatt gagtgttagt
     5221 tacttgatag cttcgaccaa gtcttgagct tgtttttcaa gtgagtttag gactgtttct
     5281 tcaagaacca attttccgtc tgcccaggca gagtcattaa cacgtgcagc agtgaaatca
     5341 ccaacgcctt gtgtacggat aaatggcaag aggtctttgt agatagcgaa aagttgatcg
     5401 tgccctgcat tggctacaga tgatactgtg acaaacttgt cttgaagggc agaaacgcca
     5461 cgtgtatcag acaagtcaag ggcacgagat agccagtcaa gcaagttttt cactgtacca
     5521 gggatagaga agttgtagac tggagagaaa atccagatag catccgcaac gagaactgct
     5581 tcacgagcag cagctacagc tggatgtgtt ggaacttcca aatcttggct gaagagagga
     5641 agggctgaat aatcaaggta gctaacttcc gctttaccag caagagcttt ctcagcttcg
     5701 agcgccattt ggtggttgaa agaaccttga cgtagtgatc cgacgataaa taatactttt
     5761 ttagacatga tgtgtctcct ttttcttaaa atttcgagaa ctctctcgtt gttataaaat
     5821 atattacaac aaaacaaaag aacttgcaag aaatttgctc agagtttatt tgaaaattgt
     5881 aaaatttcgg aaactctagt catttgtgac tgaaaaagta agaactgttt cactttcaaa
     5941 atcggttttg tttgaaggga gaaatagaat tggttgctca aagcacagct ttgaggttgc
     6001 agataaagct gacgtggttt gaagagattt tcgaagagta ttcttatatt cacttgtaat
     6061 aaagcttaat agatggtaaa atagacgagt gaaaaaaaga caaaacaaag caaaaaataa
     6121 tctactgtgg cagtatggtc tagggatgac gattttgttt gtggttatca gtgcttcctt
     6181 tctgtatatg gtttctctta gcatgaaacc ctatcaaaca gctaaaagtg aaggagaaaa
     6241 attagctcag cagtatgcag gattagagaa ggctgatcag gttgatttat acaatggctt
     6301 ggaatcttat tacagcgttc ttggtcgtaa taaacagcaa gaagcgcttg ctgtcctgat
     6361 tggtaaagat gaccataaga tttacgttta tcagctaaat cagggtattt cacaagaaaa
     6421 agcagaaacg gtttctaagg aaaagggagc tggcgagatt gacaagataa cctttggtcg
     6481 ttatcaagac aagccaatct gggaagttaa gtcaggatct gatttttatc tagtagattt
     6541 tgaaacagga gcattggtca ataaggaggg cctatgaaac tatccaaccg tgttttagaa
     6601 atggaagaaa gtgtgacttt ggctgctgga gcccgtgcca aagcactgaa ggctgagggt
     6661 agagatattt tgtctctaac cttgggtgag ccagatttca ctactcccaa aaatatccaa
     6721 gatgccgcca ttgcatcgat tcgagatggg cgtgcttctt tttatacagt aacctcaggt
     6781 ctgccagagc ttaaggcggt ggtcaatagc tactttgagc gcttttacgg ctattctgta
     6841 gcgtcaaatc aagtgacagt cgctgcggga gccaaatatt ctctctatac cttctttatg
     6901 gctgtggtca atccaggtga tgaagtcatc atcccaaccc catactgggt tagctatgga
     6961 gatcaggtca agatggcaga aggcgttccc gtctttgttt ctgctaagga agacaatcac
     7021 tttaaggtga ccgtagagca gttagaagca gctcgcactg acaagaccaa ggttttggtg
     7081 ctgaattcgc catctaatcc cacaggtatg atttacaccc gtgaggaact cttggcaatt
     7141 ggaaactggg ctgtagaaaa tgatattctc atcctagcag atgatatcta tggccgcttg
     7201 gtttataatg gtcatgagtt cacaccgatt tctagcctat cggaagcgat tcgcaagcaa
     7261 acagtggtca tcaatggtgt gtctaaaacc tatgccatga ctggttggcg gattggttat
     7321 gccgttggag aagcagacat tatcgctgcc atgtccaaga ttgcaggtca aacaacttcg
     7381 aatccgtcag cagtagccca atatgcagca gttgaggctc tatcaggtga gcaagatact
     7441 gtagaaagca tgcgtcaggc ctttgaggaa cgtcttaata ccatctatcc cctccttgca
     7501 gaggtgccag gatttgaagt ggtcaaacca caaggggcct tctatctctt cccaaatgtc
     7561 aaaaaggcca tggagatgaa aggctacacg gatgtgacag actttacaac tgctatctta
     7621 gaagaagccg aagtggcctt ggtaacagga gctggatttg gagcaccaga aaatgtccgc
     7681 ctcagctatg cgacagacct agacacgctt aaagaagcag tcgaacgctt gaaagcattt
     7741 atgggtagtg agaatgattg atcattttga gattaaggta aaggatttac aaatttcaga
     7801 aggattttat aggagttttc tcgctccttt ggactataaa ttggctttta agactagttc
     7861 tctaattagt tttctatccc cgaacagccc tcatcctggt ggtgattttt ggctgactca
     7921 gggaacacaa gatcctgttc attttgcttt tttagcagaa aataaggaag aagttcaggc
     7981 ttgttatgag gctggcttag aggcaggtgg gcgagacaat ggggttcctg gttatcgaag
     8041 tgagcatccg atttattatg ctgcttttat gattgacctg gatgggaaca atatagaggt
     8101 ggtttgccat aaagaataaa aaagaaaagg aaaaataatg acaaaacgtg taacgattat
     8161 tgatgtaaaa gactatgttg gtcaggaagt gacgattggc gcttgggttg ccaacaaatc
     8221 aggaaaaggg aaaatcgctt tcttacaatt gcgtgatgga acagccttct ttcaaggtgt
     8281 ggcttttaaa ccaaactttg tcgaaaaatt tggtgaagaa gtgggacttg agaagtttga
     8341 tgttatcaaa cgcttgagcc aagaaacgtc tgtttatgtg acaggtattg tcaaagagga
     8401 cgaacgttct aaatttggct atgagttgga catcacagac atcgaagtga tcggtgaatc
     8461 tcaagactac ccaatcacac caaaagaaca cggaacagac tttttgatgg ataaccgtca
     8521 cttgtggcta cgctctcgta agcaagtagc tgtgttgcaa atccgtaacg ctattatcta
     8581 tgcaacttat gagttctttg acaagaatgg ttttatgaag tttgacagcc caattctttc
     8641 aggaaatgcg gcagaagatt ctacagaact ctttgaaact gactacttcg gaacgccagc
     8701 ctacttgagc caatcaggtc agctttacct agaagcaggg gctatggctc ttggtcgtgt
     8761 ctttgacttt ggtccagttt tccgtgctga aaaatcaaaa acacgccgtc acttgactga
     8821 gttctggatg atggatgctg agtactcata cttgacacat gatgagtcgc ttgacttgca
     8881 agaagcttat gtgaaagctc ttctacaagg tgttcttgac cgcgcgcctc aagccttgga
     8941 aaccttggaa cgtgatacag aactcttgaa acgctacatt gcagagccat tcaaacgtat
     9001 cacttacgat caagccattg acctcttgca agagcatgaa aatgatgaag atgctgacta
     9061 cgagcatctt gagcatggtg atgactttgg gtcaccacac gaaacttgga tttcaaacca
     9121 ctttggtgtg ccaacatttg tcatgaacta tccagcagcc atcaaggcct tctacatgaa
     9181 accagttcct ggaaatccag agcgcgtgct ttgtgcagac ttgcttgctc cagaaggcta
     9241 tggagaaatt atcggtgggt ctatgcgtga ggaagattac gatgcccttg tcgctaagat
     9301 ggatgaactt ggcatggatc gtacagaata tgaattctac cttgaccttc gtaaatacgg
     9361 tacagttcca cacggaggat ttggtatcgg tatcgaacgt atggtaacct tcgcagcagg
     9421 aacaaaacat atccgtgaag ctattccatt cccacgtatg ttgcaccgta tcaaaccata
     9481 agaacaggaa aacgcccatg tggcgttttt tcgaattcta gtgtttttac ttgcgtaaaa
     9541 aaattttttc tagtataata gtttattgtg agcgaacctc acttacccct tgcaaagtct
     9601 tggggtcatt agaccaaaag gaggaacata tcaatggcta aatacgaaat tctttatatc
     9661 attcgtccaa acattgaaga agaagctaaa aacgctttgg tagcacgttt tgactctatt
     9721 ttgactgaca acggtgcaac tgttgttgaa tcaaaaactt gggaaaaacg tcgtcttgca
     9781 tacgaaatcc aagatttccg tgaaggactt taccacatcg ttaacgttga agcaaatgac
     9841 gatgcagctc ttaaagagtt tgaccgtctt tcaaaaatca atgctgacat tcttcgtcac
     9901 atgatcgtca aaattgacgc gtaagaaggt aaactatgat taacaatgtt gtacttgtag
     9961 ggcgtatgac acgtgacgct gagttgcgtt ataccccatc aaatgtagca gttgcgactt
    10021 ttactcttgc agtaaaccgt acatttaaga gtcaaaatgg tgaacgtgag gctgatttta
    10081 tcaatgtcgt tatgtggcgc caacaggctg aaaatcttgc taactgggct aaaaaaggct
    10141 cacttatcgg ggtgacaggt cgtatccaga ctcgtagtta cgataaccag caaggacaac
    10201 gtgtctacgt gacagaggtc gtggctgaga atttccaaat gttggaaagc cgtagtgtgc
    10261 gtgagggtca cacaggtgga gcttactctg caccaactgc aaactattca gcacctacaa
    10321 attcagtacc agacttttca cgtaatgaaa atccatttgg agcaacaaac ccattggata
    10381 tttcagatga tgatttacca ttctaatgga caactaaact tataaaggag aaaaaacatg
    10441 gctcaacaac gtcgtggcgg attcaaacgc cgtaaaaaag ttgattacat cgcagcaaac
    10501 aaaattgaat atgttgatta caaagatact gagcttctta gccgtttcgt ttcagaacgt
    10561 gggaaaatcc ttcctcgtcg tgtaacagga acttcagcta aaaaccaacg taaagtaaca
    10621 acagctatca aacgcgctcg cgtaatggct ttgatgcctt tcgtaaacga agattaaaga
    10681 aaagacccgg ttgggtctct ttttcatgag cttgaaaaca agaaagcgaa ttaagacccc
    10741 aacgggtctt ttttcacaag ctttgaaatg agagagcgag ttaggctcag tggctccctt
    10801 tttacgagtt tgaaaacaag agaacacatt aaaagcacga tggagctttt tcataaatat
    10861 gtctcttttc tcatccaaga aattaaaata aaaatgataa actttttgaa aataggggat
    10921 ttgcctactt tatgatataa tggaaagagt tagattgaaa gaggtagtga gatggacgcg
    10981 aaattaagat acaaggcaaa gaagatcaag attgtctttt ttgatattga tgatacattg
    11041 cggaattcaa agacagggtt tattccaact acaattccca ctgtttttaa acagttgcgt
    11101 gaaaaaggaa ttttaatagg aatcgcctct ggacgtggca tttttggtgt tgttccagag
    11161 attcgtgatc tcaagcctga cttttttgta actttgaatg gagcttatat cgaagataaa
    11221 aaaggtcagg tcatttatca gcatcagatt gaaaagtcag atgttgagga gtatatctct
    11281 tgggctaagc aagaaggaat tgagtatggc ttggttggga gtcatgatgc caagttgtcg
    11341 actcgcaccg atatgatgag tgaagctatc aatccaattt atcccgactt agatgtagat
    11401 cccgatttcc atgaaaaaga agatatctat cagatgtgga cttttgaaga taagggagat
    11461 gacttgcact tgcctgacag tctctcagac aaacttcgca tggttcgttg gcatcaacat
    11521 tcgtctgata ttgtgccgat ttcaggctcc aaagcgacgg gggtggaaaa ggttgtggaa
    11581 caccttggct tgaaaccaga gaaggtcatg gtttttggag atggtctcaa tgacttggaa
    11641 ctctttgatt atgctggaat cagcgttgcc atgggaattt ctcatgataa aatcaaagaa
    11701 aaagcggatt atattacaaa aacattagaa gaagatggca tttttgatgc cttagaagta
    11761 tttggtatgg tagaaaaaga attgcatttt ccacaagtag acattgaaac agtagaaggt
    11821 cctcttgcga ctattaagac caatcacgga gacttacgta tcaagctttt ccctgaacat
    11881 gctcctaaaa cagtggctaa ctttgtatct ctttcaaaag atggctacta tgatggtgtc
    11941 attttccacc gtattatcaa ggactttatg atccaaggtg gagacccaac tggaactggt
    12001 atgggtggcg agtcaatcta cggcgaatct tttgaggatg aattctcaga agagctttac
    12061 aatatccgtg gtgctctttc catggcaaat gctggtccaa ataccaacgg cagccagttc
    12121 tttatcgtgc aaaaccaaca cctaccttat tcgaagaaag aaattactcg tggtggttgg
    12181 ccagaaccga ttgcagaaat ctatgccaat caaggtggga cacctcacct agaccgccgt
    12241 cacacggttt ttggtcagtt agctgatgaa gcatcttacg ctgtcttgga tgccattgct
    12301 gctgttgaga caggagctat ggacaagcca gttgaagatg ttgtaattga aactattgaa
    12361 atcgaggact aagatgaaaa tcggtgataa gctaaagggg cgtattacag ggattcagcc
    12421 ctacggtgcc tttgttgagt tagagacggg tgatacgggg ctgattcaca tttcagaaat
    12481 tcggacagga tttattgaaa atattcatga aaccttgaaa gtcgatgaag aggttcaagt
    12541 tcaggtagtg gatttagatg aatttacggg gaaagccagt ctttctatcc gcactttgga
    12601 ggaagaaaag taccagtttc ctagacggag acgcttttca agcgaccgct ttaactacgg
    12661 ttttgctccc tttcgacgaa tgttaccaat ctggactgga gaagccctgc accatttaaa
    12721 aaagaagaag tagtttagag ttttatattt tttgtaatgt taatataaat ttgctataat
    12781 aggaccatgg aagaagaaca attattaaaa tcaggagagc gcattaacca gctcttttcg
    12841 acagatatca aaatcattca aaatagagag gtttttagct attcggtgga tagtgttctc
    12901 ttatcacgat ttccacgttt tcctaagaag gggttgattg tggatttctg tgctgggaat
    12961 ggagcagtgg ggctttttgc tagcactcgt actcaagcac agatattgtc tgttgagatt
    13021 caggagcgtt tggcggatat ggctgaacgc tctgtccgtt tgaatggatt agaggagcaa
    13081 atgcaggtca tctgcgatga tttgaaaaat atgcctgctc acattcaggg gagtaaggtg
    13141 gatatgattt tgtgtaatcc accctatttc aaggtggatc cttattctaa tctgaacgag
    13201 agtgaacatt atctcttggc tcgacacgaa atcacgacta atttggaaga aatctgtcgt
    13261 agtgctcaga gtattctcaa gtctaatggg cgtttggcca tggttcatcg tcctgatcga
    13321 cttctggata ttttggatac gttaaaacga cataatctag cccctaagcg cctgcagttt
    13381 gtttatccaa aaagagaaaa ggaagccaat atgcttttga ttgaggcgat caaggatggc
    13441 tcaacaagtg gctttaaggt cttacctcct ttgattgtcc acaatgatga tggctcttat
    13501 acgcccgaaa tcgaagagat ttattatgga tcataaggct tatatgtacg ttctggagtg
    13561 tcgtgatgga tcctactata taggctatac gactgatgtg agaagacgcc tcgctatcca
    13621 caatagtggg aggggagcca aatatacacg agcacgcttg ccagtcaaac ttatctatgc
    13681 tcaaggtttt gccagtaagg aagaagccat gtcggctgaa gctcttctca agcgtaagaa
    13741 gaggccacag aaggaagaat ttttatctga aaatcaagat agaaatttac tcagttattt
    13801 tgaagaatcg tggggagtcc tttgactcct cttacctttg tcaaaaagcg aaaaaaatgc
    13861 tacaataaag aaaataaaca aaatgaggta ttatcatgtc caagattcta gtatttggtc
    13921 accaaaatcc agactcagat gccatcgggt catctgtagc ttttgcctac cttgcaaaag
    13981 aagcttacgg tttggatacg gaagctgttg cccttggaac tccaaatgaa gaaacagcct
    14041 ttgtcttgaa ctattttggt gtggaagcac cacgtgttat cacttctgcc aaagcagagg
    14101 gggcagagca agttatcttg actgaccaca atgaattcca acaatctgta tcagatatcg
    14161 ctgaagtaga agtttacggt gttgtagacc accaccgtgt ggctaacttt gaaactgcaa
    14221 gcccacttta catgcgtttg gagccagttg gatcagcgtc ttcaatcgtt taccgtatgt
    14281 tcaaagaaca tggtgtagct gtgcctaaag agattgcagg tttgatgctt tcaggtttga
    14341 tttcagatac ccttcttttg aaatcaccaa caacacaccc aacagataaa atcattgctc
    14401 ctgaattggc tgaattggct ggtgtgaact tggaagaata tggtttggca atgttgaaag
    14461 ctggtaccaa cttggctagc aaatctgctg aagaattgat tgacatcgat gctaaaactt
    14521 ttgaactcaa cggaaataat gtccgtgttg cccaagtgaa cacagttgac atcgctgaag
    14581 ttttggaacg ccaagcagaa attgaagctg caatgcaagc tgccaacgaa tcaaacggct
    14641 actctgactt tgtcttgatg attacagata tcgtcaactc aaactcagaa atcttggctc
    14701 ttggtgccaa tatggacaag gtcgaagcgg ctttcaactt caaacttgaa aacaatcatg
    14761 ccttccttgc tggtgccgtt tcacgtaaga aacaagtggt acctcaattg actgaaagct
    14821 ttaatgcgta agattttggg tgtcagctca aaatcggaaa gtctagtttg ccttatatcg
    14881 aaaggagttt cggctccttt tttctaggag tgaagtatgt tagaaaatgg cgatttgatt
    14941 tttgtgagag atgggtcaga catgggacag gccatccaga cttccacagg taactatagc
    15001 catgttgcca tttatttgga tgggatgatt tatcatgcta gtggacaggc tggtgttgtc
    15061 tgtcaagaac cggcagactt ctttgagtcc aatcatttat acgacctcta tgtttaccca
    15121 gaaatggata tccagtcggt gaaggaaaga gcttgcaaac atcttggagc accctacaat
    15181 gcttctttct atccagatgc agctggtttc tactgctccc agtatatagc agaaatccta
    15241 cctatttttg aaactattcc tatgaaattt ggagatgggg agcaggagat tagtgatttt
    15301 tggagggagt attacataga actaggtctg cctgttcctc tgaaccaagc tggtaccaat
    15361 cctagtcagt tggcagcatc gcctctgtta caatgtaaag aaaggaatct tcatgattca
    15421 gatttttaat ccatctcgtt tgacgagaca gccatttttg gagaattgat ccgctatctg
    15481 gaccagtatg aggatgtgat tctacgggaa attaaggctc aatttccaga tgttgcagtt
    15541 gataaactca tggaagagta tataaaggca ggcttgattc tacgtgaaaa taagcgctat
    15601 tacctcaatt ttcctacgct tgaatcactt gatagtcttg aactggatca agagattttt
    15661 gtcagagaag ctagtccggt ctatcaagcc ttgttggagc agagttttga gacggaattg
    15721 cgcaatcaaa tcaatgcagc tattttagtt gaaaagacgg actttgcgcg cattaaaatg
    15781 accctgtcca attattttta caaggtcaaa cagcagtatc ctttgacaga aaaacagcag
    15841 gagctctatg acattttagg agatgttaat cctgagtatg ccctcaagta tatgacggct
    15901 tttttgttga aatttctcaa aaaataccag cttatgcaga aatgccgtga tatctttgtg
    15961 gacagtttgg ttgtcttagg ctatattgtg caaaatgaag atggaaagta tgagttggct
    16021 atcgattttg ataaggagag attaactttc tacttagcgt gatttcttgt ttctgagcac
    16081 attgtttgac tttccttagt attcggtata aactatatgt aaccggtaac acatatcgga
    16141 ataaactaaa ggagacaatc atatgtcact tgaaaacaaa ttggaacaag caacaggcgc
    16201 tgtcaaagaa ggttttggta aagttactgg agacagcaag acagaacttg aaggagctgt
    16261 tgaaaaaaca gttgctaagg caaaagacgt tgtagaagac gcaaaaggtg ctgtagaagg
    16321 tgccgttgaa ggtttgaaaa acgtttttac taaagaatag gaaaaaatca agggtttcat
    16381 tttcccttga ttttttctat tcttataaat aattttctgc gacggctgta tctcctgggt
    16441 aggattcttt cttgccctgg atgatttggt aacaatcggc tcccttaccc gcaataataa
    16501 ctgcatctaa ttcgtgattt gtgatagcca ttgccgcctt gatggcttct tggcgatccg
    16561 caatcttttc aacaggatga ttgatgtagt tactaatttc atctgcaatg gccattgggt
    16621 cttcatagtt agggtcatca gcagtcagaa agacttgaat ctcagggtgt tgattgagga
    16681 ggaggccaaa gtccttacga cgactttctc ccttgtttcc tgttgatccc agaaccagag
    16741 caatctttcc ggtttgatga gtttcaacca cattgatgag ttttttcaga ctatccccat
    16801 tgtgggcata gtcgatgaag accttggctc catttttctg agtgaggact tccatacgac
    16861 caggaacgcg ggttgcagcg atgccttttt tgatgtcctc aagacttgct ccgagacgga
    16921 gacaagcaag tccagcagca actgcatttt cttggttgaa gttgccaatg agttggatat
    16981 cataatctcc agcgagttta cccgtagctg aaaagctaaa ggctttggaa ttctcgattt
    17041 ggttatcaaa ttggctacca tagaaatcat ggtcttgatc ttcaacctgt tctctcaaga
    17101 ctgagaagtg gtccatgtca ctgttaatga tgactgctcg gctattttcc atcaagagac
    17161 gcttgtggta gaaatagtct tcaaagctag ggtgttcaat cgggccgata tggtctgggc
    17221 tgatatttag gaaaactccc acatcaaagg tcagtccata gactcgatgg actagatagg
    17281 cttgactgga gacttccatg atgaggtgag tacggtcatt ttgcacagcc tgattcatca
    17341 tgtcaaagag gtcaatactc tcaggggttg tcaacgctga cttaaagaaa gtctcgccat
    17401 caagagttgt gttcatggtc gacaacatag caggtctatg cccttgagat aagatgttat
    17461 aggcgaaata ggttgctgtt gtcttaccct tagtaccagt aaaggcaagg agtttgagtt
    17521 tctcttgtgg attaccatag aactccatgg caatcaaact catggctttc tttatatcgt
    17581 tcacaatgat gacagggata tcgacttcgt agtccttttc agctacatac caagctaaac
    17641 cttgtgttat agcagaaaga aggtattctt ttttaaaggc agcgcctttt gcaaaaaaaa
    17701 gagtgtcttc tgttactttt cggctgtcgt agctgatgct atcaaaaata actttgctgt
    17761 agttgtagtg gtaatgacct tggtcaataa tttcgcgaaa aaggccatct ttctttaaaa
    17821 tatctaatac ggtttcaatc ttaatcatac tttctattgt aaaccgaaag tcgtaaattt
    17881 acaagtaaca aggaaaagtt tataatggaa gataaggagt ttttcctagt tatcaaaatt
    17941 gaatgaggaa tctatgtcgc acgaaaacaa tcaccagcag gcccagatgt tacgggggac
    18001 tgcttggcta acggctagta actttatcag tcgcctactc ggggctgttt acattatccc
    18061 ttggtacatc tggatggggg cttatgcagc taaggcaaat ggtctcttta ccatgggtta
    18121 caatatctat gcttggttct tgttggtttc aacagcgggg attccagttg cggtggccaa
    18181 gcaagttgcc aagtataata ccatgcgaga agaagagcat agctttgccc tgattcggag
    18241 cttcttaggc tttatgacag gactaggcct ggtttttgct ttagtcttgt atgtctttgc
    18301 tccttggcta gcagacttgt ctggcgtggg caaagacttg atcccaatca tgcaaagctt
    18361 ggcttgggga gtcttgattt tcccgtctat gagtgttatc cgaggatttt tccaagggat
    18421 gaataacctc aaaccctatg ccatgagcca aattgctgag caggtcattc gtgttatctg
    18481 gatgctccta gcaaccttta tcattatgaa gctcggttca ggagattatc tagcagccgt
    18541 tacccaatca acctttgctg cctttgtcgg tatggtagcc agttttgcag tcttgattta
    18601 tttccttgcc caagaaggtt cactcaaaag agtctttgaa acaggagata agattaacag
    18661 taagcgtctc ttggttgata ccattaagga agccattcct tttatcctga cagggtctgc
    18721 catccagctc ttccagattt tggatcagct gacctttatc aatagtatga gctggtttac
    18781 caactacagc aatgaggact tggttgtcat gttttcttat ttctcagcca atcctaataa
    18841 aatcacgatg attttgattt ctgtaggggt ttcgattggg agtgttggtt tgccactttt
    18901 gacggaaaac tatgtcaagg gggacttgaa agcggcttct cgtctcgttc aggacagtct
    18961 caccctactc tttatgttct tgctaccagc aacggttgga gtggttatgg taggagaacc
    19021 tctttatacg gtcttctatg gtaagccaga tagtttggct ctgggcttat ttgtctttgc
    19081 agttttgcag tctattattt taggcttgta catggtcttg tctccaatgc ttcaggccat
    19141 gttccgcaac cgcaaggccg ttctctattt tatctatggt tctattgcca agctagtctt
    19201 gcaactacct accatcgccc tcttccacag ttatggtcct ttgatttcaa caaccattgc
    19261 tctcatcatt cctaacgtct tgatgtatcg ggatatttgt aaagtaactg gtgtcaagcg
    19321 caaggtgatt ttgaagcgaa ccattttaat cagtttgctg accctagtca tgtttctgtt
    19381 aataggaacc atccagtggc tgttaggatt tttcttccaa ccaagtggac gtttgtggag
    19441 cttcttttat gtagctcttg tcggtgccat ggggggtgga ctttatatgg ttatgagtct
    19501 gcgtacctat ttattagata aggtaatagg aaaagcccaa gcagatcgcc tgcgagcaaa
    19561 atttaagctt tcgtaaggta gcatttataa ataaaaggaa taagttgaac aatcttttag
    19621 gagaacttga aacttattcc ttttttagcg tcaaaatagc taaaattatc tttcaaaaat
    19681 agaaaatgag gtttttttga ttttttggaa aaaacaattg actaaacaaa ccaagagttg
    19741 tataataaaa caaatattta aagcaggagg ttctggaaat gaaaaagtct aagagcaaat
    19801 atctaacctt ggcaggtctt gtcctgggta caggagtttt attgagcgcg tgtggaaatt
    19861 ctagcactgc atcaaaaacc tataactatg tttattcaag tgatccatct agtttgaact
    19921 atctagcaga aaaccgcgca gcaacatccg atattgttgc aaatttggta gacgggttat
    19981 tagaaaatga ccaatatggg aatattattc catcattagc agaggattgg actgtttctc
    20041 aggacggttt gacctatacc tacaaacttc gtaaggatgc caagtggttt acttctgagg
    20101 gagaagaata tgcgcctgta actgcccagg attttgtgac aggtttgcaa tatgcagctg
    20161 ataaaaaatc agaagctttg tatctagtgc aggactctgt tgctggtttg gatgactata
    20221 tcactggtaa aacaagcgac ttttcaactg tcggtgtcaa ggcacttgat gaccaaacgg
    20281 ttcaatatac tttggttaaa ccagaacttt actggaattc aaaaacactt gcaacgatac
    20341 tttttcctgt taatgcagat ttcctgaaat caaaagggga tgattttggg aaggcggatc
    20401 catctagtat tttgtacaat ggacctttct tgatgaaagc acttgtctca aaatctgcta
    20461 ttgaatataa gaaaaaccct aattactggg atgctaagaa tgtctttgta gacgatgtga
    20521 aattgaccta ctatgatggt agcgaccaag aatcactgga acgtaatttt acagctggtg
    20581 cttatactac ggctcgtctt tttcctaaca gctccagcta tgaagggatt aaagaaaaat
    20641 acaaaaacaa tatcatctat agtatgcaaa attcaacttc atatttcttt aattttaacc
    20701 tagataggaa gtcttacaat tatacttcta aaacaagtga cattgaaaag aaatcgaccc
    20761 aggaagcagt tctcaataaa aacttccgtc aggctatcaa ttttgctttt gacagaacat
    20821 cttatggggc tcagtctgaa gggaaagaag gtgcaacaaa gattttgcgt aacctagtgg
    20881 ttcctccaaa ctttgtcagt atcaagggaa aagactttgg tgaagttgta gcctctaaga
    20941 tggtcaacta tggtaaggaa tggcaaggta tcaactttgc ggatggtcaa gacccttact
    21001 acaatcctga gaaagccaag gctaagtttg cggaagctaa gaaagaactc gaagcaaagg
    21061 gtgttcaatt cccaatccac ttggataaga ctgtggaagt aacagataaa gtaggcatac
    21121 aaggagttag ttctatcaaa caatcaattg aatctgtttt aggttctgat aatgtagtga
    21181 ttgacattca gcaattaaca tcagatgagt ttgacagttc aggctacttt gctcaaacag
    21241 ctgctcagaa agactatgat ttatatcatg gcggttgggg acctgattat caagacccgt
    21301 cagcctatct cgatattttt aatactaata gtggaggagt tctacaaaat cttggactag
    21361 agcctggaga agccaatgac aaggctaagg cagttggact ggatgtctat actcaaatgt
    21421 tggaagaagc taataaagag caagatccag ccaaacgtta tgagaaatat gctgatattc
    21481 aagcttggtt gattgatagt tctttagttc ttccaagtgt ttcgcgtggg ggaacaccat
    21541 cattgagaag aaccgtacca tttgctgctg cctatggttt aaccggtaca aaaggggttg
    21601 aatcatataa atacctcaaa gtacaagata agattgtcac aacagacgaa tatgcaaaag
    21661 ccagagaaaa atggttgaaa gaaaaagaag aatccaataa aaaagcccaa gaagaattgg
    21721 caaaacatgt caaataaaat ctaattgtag ataagtttgt gtaagaagtc tttgtgctta
    21781 aaaacgcata atatcaggta tataaaatcc tagatgttat gcgttttgtt ataggaagat
    21841 ttattagatt ttatcctcaa attgagttat tcccgacttt atccgttgaa atattataag
    21901 gagtatttat gaaattaaaa ttattaagag tagatactaa ggtgattatg gggagtttct
    21961 tacttgttct gtctagtcta cttgctttgt tgcttcccct tatcttaaag ggtttaatag
    22021 atgggagttc tattgaaaat ataggttcca aagtatttca atcgtattgg tcaagccttg
    22081 ttttcttcta ttggttacta tctgtttagt caatcgggtg aaaaaaagat agcaaaaatc
    22141 aggaaaaaag tgatagaggg gttgatttat gcagagaaat ccttctttga taagagccaa
    22201 agtggggagt tgacttctgc cattgtcaat gacatgagtg tcattcgtga gtttttaatt
    22261 acgactttcc caaatattat tctgagttta gttatggtac ttggttccat tgtagtctta
    22321 tttagtcttg attggaatct ttctctactt ttattcatca ctcttccttg tatgatgttt
    22381 attatcttgc ccctttccaa tatcagtgaa aagtatagtc gtcgtttaca ggaggaaatt
    22441 taacagggca attgactgaa aagattcaag aacatgaatt aattaagact aaccaagcag
    22501 agaaaagtgt acaggatgtt ttggataatt gtattgaaag ggtacaaaac aattcactga
    22561 aatcagatag ggttacttct tttgagaccc cgtttgctct cttatttatc tttgcgacta
    22621 tagctgtgat gctaacctat gggggttatc gggtcagcgc aggatatata tctgtgggaa
    22681 ccttggtttc gtttttgatt tacctctttc aattacttaa tcctattagt aatatagcta
    22741 attttgtaac tgtttattct aggagcaagg gatcttcagt tgcactggat aacttgcttg
    22801 cagttcctaa agaaaaattt gagggaggaa aatcggtatc aggacaaggg ttgaatttta
    22861 accatgtcta ttttggttat gatgaaaatc gacctgtctt aaaggatatt acttgttcaa
    22921 ttttcaaggg gcaaaaattg cttttgttgg accatctgga tcaggaaaat caacgattgt
    22981 gcgtttgtta gagcggtttt ataaaccgct ttcaggagat attctaatgg agcaatcaag
    23041 tatatatgat tttaacttaa aagaatggag aagtaaaatc gcttgggttt cacaaaataa
    23101 tgcagtctta tctggcagta ttcgtgacaa tctttgtctc ggtttgaatc gcttagtaac
    23161 tgatgatgaa ttgatgaaag tgctagactt agtatcacta ggtgatgaga ttcgctccat
    23221 gaaagaggga ctagatactg aagttggtga acgcggacga ttcttgtcag gggggcaaag
    23281 ccaaagactt caaatagcta gaacctactt aaaagatgct gaaattctta tatttgatga
    23341 agctactgct aatcttgatg cggattctga gtatgcgatt atcagtagcc tctattctgt
    23401 attaaaggag aagacggttg tgattatagc gcatagtttg tcaacggtaa aagatgtgga
    23461 ttgtattttc ttcttagagg aggggaaaat cactggctca ggaactcata aggaactact
    23521 ggaaaatcat gagcgttatg cttgttttgt gcaggagcaa atgatagagt gaagtgtctt
    23581 ttgagattca ccattttata gtctattaaa gggagcagga aaaactccct ttttatatag
    23641 tttgaaacta taactagctc ttgaaaagaa gaaaatgagt tgatgaaaat aagtggtaca
    23701 atagttacta tagatttgga ggtattgtat gagcaaggaa ttacacatta acacaatttt
    23761 ggcccaggcg ggtattaagt cagatgaagc gacaggtgca ttggtgacac cgcttcattt
    23821 ttcaacgacc tatcagcatc cagagtttgg tcgatctact gggtttgact atacgcgcac
    23881 taaaaatcca actcgtagta aggctgagga agtcttggcg actattgagt cagcagacta
    23941 tgccttagcg actagctcag ggatgtcagc tattgtactg gcctttagcg gctttccagt
    24001 aggaagtaag gtcttggcag tgcgtgatct ttacggcggt tcttttcgct ggtttaacca
    24061 agtggagcag gaaggtcgtt tccattttac ctatgccaat acagaagaag agttgattgc
    24121 cgagttagaa aaggatgtgg atgttctcta tatcgaaacc ccaaccaatc ccttgatgtt
    24181 ggaatttgat atcgaaaaac tagcaaaatt ggctcatgct aagggtgcca aagtggtggt
    24241 ggacaatacc ttctatagcc ctatctacca acgtccgatt gaagatggag cagatatcgt
    24301 tctccattca gcaaccaagt atctagcagg ccacaatgat gtcttggctg gagtggttgt
    24361 gaccaatagt ttagaactat acgagaagct tttttacaat ctcaatacaa caggggcagt
    24421 cttgtctcca tttgacagct accagttgct tcgtggtctc aagaccttgt ctcttcgtat
    24481 ggagcgctca acagctaacg cccaagaagt ggttgccttt ttgaaggatt ctccagcagt
    24541 taaggaagtt ctctacactg gtcgtggagg catgatttcc tttaaagtag ccgatgaaac
    24601 acgcattcct catattttga acagtctcaa ggtcttctct tttgcggaaa gtttgggcgg
    24661 agtggaaagt cttattactt atccaacgac tcaaactcat gctgatattc cagcagaagt
    24721 acgccattct tatggtttga cagatgacct cttgcgtttg tctattggga ttgaggatgc
    24781 tagagatttg attgcagatt tgcgccaagc cttagaagga taagacaaag atgggaaaat
    24841 atgattttac aagcctgccc aaccgtttag ggcaccatac ctataaatgg aaagaaacag
    24901 aaacggatag tgaagttcta ccagcttgga tagcggatat ggactttgtg gtcttgcctg
    24961 aaatccgcca agccgtgcaa atttacgcag accaactggt ttatggttat acctatgcca
    25021 gtgaagactt aattaaggaa gttcaaaagt gggaagctac acaatacggt tacaactttg
    25081 acaaagaggc tcttgtcttt atcgagggtg tggtaccagc catctcaaca gctattcaaa
    25141 cctttacaaa agaaggcgag gcggttttaa ttaacacgcc tgtctaccca ccctttgctc
    25201 gcagtgtcaa gttgaataat cgtagattga ttactaattc cttagtggaa aaggatggtc
    25261 tgtttgagat tgactttgac caacttgaaa aggatttggt ggaagaggag gttaaactct
    25321 atattctttg caaccctcac aatcctggtg gacgtgtttg ggaaaaagaa gtgttggaga
    25381 agattggcca actctgccaa aaacacggtg ttttgttagt ttcggatgag attcaccaag
    25441 atttgaccct ctttggtcac aaacaccagt ctttcaatac catcaatcct gccttcaaaa
    25501 attttgctat cgtcttgagc agtgccacta aaacatttaa tattgctgga acaaaaaatt
    25561 cctatgcagt cattgaaaat cctaagttga gactagcttt ccagaaacgc ctgttggcca
    25621 ataatcagca tgaaatttca ggcttgggtt atttggcgac agaagctgcc tatcgatacg
    25681 gtaaagattg gctagaggaa ctcaagcaag tctttgaaga ccacatcaat tatgtggtgg
    25741 atctatttgg aaaagagact aaaatcaagg tcatgaaacc gcaaggtacc tacttgattt
    25801 ggcttgactt ttcagcttat gacctgactg atgaaacatt gcaagagttg ttgagaaatg
    25861 aagccaaggt tatcctcaac cgtggtttgg attttggaga ggaaggaagt ctccatgccc
    25921 gcatcaatat agctatgccc aaatctctgt tgcaagaagt ctgtcagcgg attgtggcta
    25981 cttttgccaa acgttaaaaa tccagccttc taggagaaaa gtcttcctag aaggctattt
    26041 tcataggcga aaatatggta taataaaaag ataaggtaaa ggtgaaaata tggctaaatt
    26101 gattccgggg aaaattcgta tcgaaggtgt tgccctttat gaaactggta aggttgatat
    26161 catcaaggaa aagaacaatc ggctctacgc tcgcgttgca gaagaagaac tgcgctatag
    26221 tttagaggat gatttggttt tttgtgcctg tgattttttt caaaagaggg gttactgtgt
    26281 gcatttggca gcgctagagc attttctgaa aaatgatgag cgtggtcagg aaatcttgtg
    26341 gagtctggaa gaaggtcatg aagaaaaaga ggctgttgaa accaaggtaa ccttgggtgg
    26401 caagtttttg gatcgaattt tatctccaaa atcagaatgc gcctatgagt tatcagctgt
    26461 gggtcaggtg gaagcaggaa ccaatcatat cttgtggact ctgagaatcg gccaaatcaa
    26521 tagccaaaaa tactatgtca ttcgggatat tccacttttt ttaaggattg tcgagcagag
    26581 aaagtcgtat atgattggca agatttatga ggagtctctt tcttgggaag cctttgatga
    26641 tgccagccaa gaacttttga ctttcttgca cggactaacg gaggaagggc tggtttcaga
    26701 cctctttttc caaaaccaag gtcggcacct ctttttccct ctgacctttt ttgagcaggg
    26761 tgtgaattta ctgatggcct tgccccattt tcaatttgac catcaagtgg atagctacca
    26821 aaccctgctt tttcaggata tgcatgctga tgccaatcta tttgccttta cagtaacaga
    26881 atactcggac tattttgaaa tggaaatcag tgagagtcct agggtcaatg tcttttatca
    26941 gggagcagta cttttccata aaggtcaggt ttatttttta acagaccagc agatgcgtct
    27001 tctcaaggaa attaaagcgt tacctgtggg tcaacaagga aagaaatacc tgcaatttga
    27061 tagcagtgat cgagacaaat tggcctcctg tctgactctt tttatccaga tgggcaccgt
    27121 ttcagctcca gaacgtctac aaatcaaaac ttttgcgccc tctttttact ttgacaggga
    27181 agaagataat cggattcgtt tagaaattca gtttgattat ggaaatagac aggtatctag
    27241 ccgacaagag ctagaagaat taccattttc aagtgacgcg gacttagaag aaagaatttt
    27301 ccaagtctgt ttggctgcgg gctttgaagc cgattttcaa tcttggcgtc aggccttaaa
    27361 agcggagtct gtctatcatt tttttcatga tatcattcca gtctttgaaa aactcgggca
    27421 tgttgaccta tcagataaac tagaagagct ttatagccta gcgagtcctc aggtgcagat
    27481 tgcctccaag ggaggtctct tggaaatcca gtttgatttt caagatattg cccaggagga
    27541 aatcgaccaa gccatgcagg tcttggttgc caatcaggat ttttatattg attcgtctaa
    27601 tcaagtttac tttttcgatg aagaaaccaa gaaaattcgc caaaatctac aggaactggg
    27661 gcaatttgaa ttaaaagatg ggaccttgca ggctcggaaa tccttggcct acagtttagc
    27721 tcatctcttt gaagggcgag accgtgtttc tttttcacaa gaattccaga atctggccca
    27781 ggatttgaca catccagagg actttcctcg acaggcaact caggttcagg ctgacttgcg
    27841 agattatcag gaaaagggaa ttggctggtt gcagatgctc catcattatg gttttggtgg
    27901 gattttggct gatgatatgg gacttgggaa aacccttcag accattgctt ttttgactag
    27961 tcaagtgaca aaagaaagtc gggttttgat tctcgctccg tcaggtttga tttacaactg
    28021 ggcagatgag tttcagaaat ttgccccaca gttggatgtg gctgttgttc atggtttgaa
    28081 agcaagtcgt gaggagattc ttgccgagag ccatcaaatc tatgtgacta gctatgccac
    28141 cttccgtcag gacagtgagt tttatcaggg gatggccttt gacttccttt tcttagatga
    28201 ggctcaggtc atgaaaaatg cccagaccaa gattgcccag accttgagac aatttgtggt
    28261 gccgtcggtc tttgccttgt caggaactcc gattgaaaac catctgggtg agttgtggtc
    28321 tattttccaa atcgtcatgc ccggactttt gccaagcaag aaagaattta tgaaattgcc
    28381 agcagagcga gtggctcagt ttatcaagcc tttcgtgatg cgacgcaaga aagaagaagt
    28441 tctgactgaa ttgccagact tgattgaggt ggtttataaa aatgaactgg aagaccagca
    28501 aaaggctatt taccttgccc agttacaaca gatgcgagac catctggctc aagtgtcaga
    28561 acaggaattt cagcgaagtc gtgtggaaat tttatctggt ttgatgcgct tgcgtcaaat
    28621 atgtgacact cctgccctgt ttatggaaga ttatcaggga gccagcggca aactagatag
    28681 tctccgagac ctactggtac aggtggcaga cggcggacac cgtgtcttga ttttctctca
    28741 gttcaaggga atgttggaaa aaattgaaca agaactgcca gacttgggcc tgacatcctt
    28801 taaaattacg ggttcaaccc cagccaagga aagacaagac atgaccaagg cctttaacca
    28861 aggagaaaga gatgcctttc tgatttccct caaggctggt ggggtcggtc tgaacctgac
    28921 aggtgcagat acagtgatct tggttgacct ttggtggaat cctgcggtgg aagcgcaagc
    28981 cattggccgt gcccatcgga tgggtcagga agaaacggtt gaggtctatc gcttggtgac
    29041 caagggaacc attgaagaaa aaattcagga actccaagaa caaaagaaac atctggtgtc
    29101 acaagtattg gatggcacag agtcacgtgg tagtctgacc ctagcagaaa ttagagaaat
    29161 tttgggaatt tctgaagcca gcacttgaaa aatcaagaca atacgctata atgaagtgtt
    29221 gaaaggaaat agaaaatgaa acaagaacga tttccattgg tgtcagatga cgaggtcatg
    29281 ttgactgaaa tgccagtcat gaatctctat gatgagtctg atctgatcag taatatcaag
    29341 ggtgagtatc gagataaaaa ttatttagaa tgggctccta ttactgaaga aaaaccagta
    29401 aaaccgattg aaaagcaagt cgaaaaacct aaaaaggctc ctttaggggt taaaaaagaa
    29461 ggaaagagct atgcggaggt ggcgcgtgaa gaagcgcgtg cggacttgaa aaagaaacgc
    29521 tctgctaact acctaactca ggatttcagc cttgcgagac gtcattctca gcccagtcta
    29581 gttagacagg gcaatcaacc gacaactcct ttccaaaagg aaaatcctgg tgaatttgtc
    29641 aaatatagcc aaaaattgac ccagtctcat tatatcttgg cggaagaagt tcattctatc
    29701 cctaccaaga atgaagaagt gtcagcacct gctccaaaga aaaacaatta tgattttcta
    29761 aagaagagcc aaatctacaa taaaaaaagt aaacaaacag aacaagaacg tcgggttgcc
    29821 caagagttga atctgaccag aatgacagaa taggggagaa aacatgtcaa agacatatca
    29881 ttttatcgga attaagggat cagggatgag tgccttggcc ttgatgttgc accagatggg
    29941 gcacaaggtt cagggatcag atgttgaaaa gtactacttt acccaacgcg gtcttgagca
    30001 ggcaggaatt accattcttc cttttgatga aaagaatcta gacggtgata tggaaattat
    30061 cgctggaaat gcctttcgtc cagataacaa cgtcgaaatt gcctatgcgg accaaaatgg
    30121 tatcagctac aaacgttacc atgagtttct aggtagcttt atgcgtgact ttgttagcat
    30181 gggagtagca ggagcacatg gaaaaacttc aacgacaggt atgttgtctc atgtcttgtc
    30241 tcacattaca gataccagct tcttgattgg agatgggaca ggtcgtggtt cggctaatgc
    30301 caaatatttt gtctttgaat ctgacgaata tgagcgtcac ttcatgcctt accacccaga
    30361 atactctatt atcaccaaca ttgactttga ccatccagat tatttcacaa gtctcgagga
    30421 tgttttcaat gcctttaacg actatgccaa acaaattacc aagggtcttt ttgtctatgg
    30481 tgaagatgct gaattgcgta agattacgtc tgatgcacca atttattatt atggttttga
    30541 agctgaaggc aatgactttg tagctagtga tcttcttcgt tcaacaactg gttcaacctt
    30601 caccgttcat ttccgtggac aaaacttggg gcaattccac attccaacct ttggtcgtca
    30661 caatatcatg aatgcgacag ccgttattgg tcttctttac acagcaggat ttgatttgaa
    30721 cttggtgcgt gagcacttga aaacatttgc cggtgttaaa cgtcgtttca ctgagaaaat
    30781 tgtcaatgat acagtgatta ttgatgactt tgcccatcat ccaacagaaa ttattgcgac
    30841 cttggatgcg gctcgtcaga aatacccaag caaggaaatt gtagcagtct ttcaaccgca
    30901 tacctttaca agaaccattg ccctgttgga cgactttgcc catgctttaa accaagcaga
    30961 tgctgtttat ctagcgcaaa tttatggctc ggctcgtgaa gtagatcatg gtgacgttaa
    31021 ggtagaagac ctagcaaata aaatcaacaa aaaacaccaa gtgattactg ttgaaaatgt
    31081 ttctccactc ctagaccatg acaatgctgt ttacgtcttt atgggagcag gagacatcca
    31141 aacctatgaa tactcatttg agcgtctctt atctaacttg acaagcaatg ttcaatagga
    31201 tgttcccatg gaaattccaa ttaagatcat tcaggcaagc aagtctgatt tgcctgagat
    31261 aggggcactt cagacctcgt cttttccagc tgaaaagcag caactttccc atattttaga
    31321 agaaagtatc cgtaagtgtg cggatacctt tcttctagct agggatgaaa atcaactttt
    31381 aggctatatt ttatcaagtc cccagtcaga caatccgcaa tgtctaaaag tacattcttt
    31441 agtcatcgag tctgaccatc agagacaggg cctgggaaca cttcttcttg cagccttgaa
    31501 agaggtggca gttgagctgg attgcaaagg gattcgtttg gagagtcctg atgagctgct
    31561 ttcctatttt gaaatgaacg gttttgttga tgaagaagaa actttgctct atgcaactag
    31621 ccagggctat agtatgattt ggtttaatcc cttttatctg gaggaacaat gaaaatcaga
    31681 caagcaagat tagaagattt ggatcggatt gttgaacttg aatttgaaaa tttttcggtc
    31741 gaagaagcca ttcctccttc tgtctttgaa gcacatttga gagaaattca gacctctttt
    31801 ctggttgctg aaaaagaagg aagaatcatg ggttatatcg aaggaccagt tggcctgcac
    31861 cgccatctgc aagaccagtc ttttacagaa gaaataaaag actatagtca tgagcctggt
    31921 ggttatatct ctgtgacctg tctgtctatt gccaaggagg cacagggact cggactgggt
    31981 cagaaattgc tgacagcctt gaaagaagtt gctcttgaag atgagagaga tggcattaat
    32041 ctaacctgtc atgactatct catcgcctac tatgaaaaac atggatttgt caacgaaggc
    32101 cagtcccagt caacctttgc aggggaaaca tggtatgata tggtctggga aatgaaaaaa
    32161 taagttagga aaagtatcat agattgcttt ttttggactt ttaagatata atattatgga
    32221 ttatcaacaa ggaggaaaaa cttttgagtg aaaagtcaag agaagaagag aaattaagct
    32281 ttaaagagca gattctgaga gatttagaaa aagtaaaagg ctatgatgaa gttctgaaag
    32341 aagatgaggc agtagttcgc actcctgcaa atgaaccttc agctgaagaa ctcatggctg
    32401 attccttgtc aacggtagag gagattatga gaaaagctcc taccgtgcct actcacccaa
    32461 gtcaaggtgt accagcttct ccagcagatg agattcaaag agaaactcct ggtgttccaa
    32521 gtcatccaag tcaagatgta ccttcttctc cagcggaaga aagtggatca agaccaggtc
    32581 caggtcctgt tagacctaag aaacttgaaa gagaatacaa tgaaacccca acaagggtag
    32641 ctgtttccta tacgacggca gagaaaaaag cagaacaagc aggtccagaa acacctacgc
    32701 ctgctacaga aacagtggat atcatcagcg atacatcacg tcgtagccgt agagaaggag
    32761 caaaacccgt taaacctaag aaagagaaga agtcacatgt gaaagctttt gtgatttcat
    32821 tccttgtatt ccttgccttg ctctcagcag gtggttactt tggttaccag tacgtgctag
    32881 attctttgtt acctatcgat gctaattcta agaaatatgt gacggttgga attccagaag
    32941 gttcaaacgt tcaagaaatc ggtacgacgc ttgaaaaagc tggtttggta aagcatggtc
    33001 tgatttttag tttttatgcc aagtataaaa attataccga cttgaaagca ggttactaca
    33061 atttgcaaaa gagtatgagt acagaagact tactcaaaga gttgcaaaaa ggtggaacag
    33121 atgaaccgca agaacctgta cttgcgactt tgacaattcc agaaggttat accttggatc
    33181 agattgctca aactgtgggt caattgcaag gtgacttcaa agagtctttg acagcggagg
    33241 ctttcttggc taaagttcaa gatgagacgt ttatcagtca agcagtagcg aaatatccta
    33301 ctttactgga aagtttgcct gtaaaagaca gcggtgcgcg ttatcgtttg gaaggatacc
    33361 ttttcccagc tacatactct atcaaggaaa gcacaactat tgagagcttg attgatgaga
    33421 tgttagctgc tatggataag aacctatctc cttactatag tactatcaaa tctaaaaact
    33481 tgactatcaa tgagttgttg accattgctt ccttggtcga aaaagaaggt gccaagacag
    33541 aagatcgtaa gctcattgca ggtgtattct acaatcgttt aaatcgtgat atgccacttc
    33601 aaagtaatat tgcaatcttg tatgcccaag gaaaactggg gcaaaatatc agtctagctg
    33661 aggatgttgc gattgatacc gacattgatt caccttataa tgtttataaa aatgtaggtc
    33721 tcatgcctgg tccagtcgat agtccaagtc tggatgcgat tgagtcaagc atcaatcaaa
    33781 ctaagagcga taacctctac tttgtagcag atgtcacaga aggcaaggtc tactatgcta
    33841 acaatcaaga agaccacgac cgcaatgtcg ctgaacatgt caacagcaaa ttaaactaaa
    33901 caaactaaaa ttatgtgata cttcacataa ttttctttag aaaatattat cagaagaaag
    33961 ttgagaaaaa tggcagaaaa aacatatcct atgacccttg aggaaaagga gaaacttgaa
    34021 aaagaattag aagaattgaa attggttcgt cgaccagaag tggtagaacg cattaagatt
    34081 gcccgttcat acggtgatct ttcagaaaac agtgagtacg aagcagctaa ggatgaacaa
    34141 gcctttgtcg aaggacaaat ctctagctta gaaacaaaaa tccgctatgc tgaaatcgtc
    34201 aatagcgacg cagttgccca ggacgaagta gcgattggta aaacagtcac catccaagaa
    34261 attggtgagg acgaagaaga agtttatatt atcgtaggtt cagctggtgc ggatgccttt
    34321 gcaggtaagg tttcaaatga aagcccaatt gggcaggcct tgattggcaa gaaaacaggt
    34381 gacacagcaa ccattgaaac gcctgttggt agctatgatg taaaaatctt gaaggttgaa
    34441 aaaacagcct aaaaacagaa aaaggagtgg ggaggcgatg tgcttcactc actccttttt
    34501 ccattttgct attcttcgaa aatctcttca aaccacgtca gcgtcgcctt gccgtatata
    34561 tggttactga ctttgtcagt ttcatctaca acctcaaaac catgttttga gctgacttcg
    34621 tcagtttcat ctacaacctc aaaacggtgt tttgagcagc ctgcgcctag tttcctagtt
    34681 tgctctttga tttttattga gtattagatg tatagtgcat tgaagttaaa atagtacact
    34741 ttgatttcta agacattgtt agaaattaga ttaaattcct taatcgattt gcgcatgttt
    34801 tatttcattt cattatactt tagattggaa aataaggaat cacataaatc gcaagaaata
    34861 gggaatctga ttcgtgttta taaccgttca aaaagagaag aggctgaaag tgagccactt
    34921 aatctttatg tcgaagatga aaagggcaat ctccttgcgg gtttgatagc agagactttt
    34981 ggaaattggc tagaaatcga gtatttgttt gtaaaagagg aactgcgagg gcaaggaatc
    35041 ggttcaaaac tattgcaaca ggcagaaagt gaagctaaga atcgaaattg ttgttttgcc
    35101 tttgtcaata cttaccagtt ccaggcaccg gacttttatc agaaacatgg ctacaaggaa
    35161 gttttttctt tgcaagacta tctctacatt aggcaaagat attattatca aaagaatctg
    35221 taaggtgagt atggaggtgg actgatatat atgagtaact atcgataaat accagttata
    35281 acctagaaat tgtgtctttc tagacgatat tgaggacaat ataatcgtag ccccaaaatt
    35341 aggaatcaag gcttatcagg ttaagaaaag aagtgatgtt gttgatattt taaaacaatt
    35401 tatttaaact aaaaactctc tatcttttta aattgacatt aatccgagat tcccctctcg
    35461 gattttgtgt tgctttcatt aaatttacag gtaagacttg ctagcttcag taaatataca
    35521 caagtttttc agaatagagt gaaatccaaa agaaaatgga aataatgaaa gctcttgtag
    35581 gcataagaaa acacctttgt gttatacttg ttgttcaacc acaaacacaa gaaaggcaca
    35641 gagatgcaaa accattatac tacaaaaggc gaacaaaggg aaatcaaata gagaaattgc
    35701 ctctctactt ggaaaagctc ctcaaactat ccacactgaa atcaagcgta ggacagtccg
    35761 acaatgtctt ggaaaagggc gcttcaaaga ggtttattct gccgactatg ctcaacagtc
    35821 ttatgaaaac aatcgcaagc gctcggtcaa gaaatcaagc ttgaccaagg aactaaagga
    35881 aaagattctc cactatcata accaaaaatt ttcgcctgaa atgatggtta tggctaaagg
    35941 ggttaacgtg ggaatttcaa ccatttacta ttggattcat catggaaaat tggggttaag
    36001 caagcaggat ttgccttacc ctagaaaagg aaaagcgctt aagaaacagg ctagcaccaa
    36061 ctttaaacct gctggtcaat ccatcgaaca gcggc
//
LOCUS       DBJKQU010000015        35491 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.015, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000015 DBJKQU010000000
VERSION     DBJKQU010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35491
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.015"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(<1..245)
                     /locus_tag="ACSUUC_000862"
     CDS             complement(<1..245)
                     /locus_tag="ACSUUC_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHQ8054102.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESN"
     gene            222..494
                     /locus_tag="ACSUUC_000863"
     CDS             222..494
                     /locus_tag="ACSUUC_000863"
                     /inference="COORDINATES: protein motif:HMM:NF036719.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide-binding domain-containing protein"
                     /protein_id="HHQ8054103.1"
                     /translation="MFTCFIIHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSG
                     KIKYHEDSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            739..2073
                     /gene="trmFO"
                     /locus_tag="ACSUUC_000864"
     CDS             739..2073
                     /gene="trmFO"
                     /locus_tag="ACSUUC_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HHQ8054104.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2157..2894
                     /gene="pyrH"
                     /locus_tag="ACSUUC_000865"
     CDS             2157..2894
                     /gene="pyrH"
                     /locus_tag="ACSUUC_000865"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HHQ8054105.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHLDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2903..3460
                     /gene="frr"
                     /locus_tag="ACSUUC_000866"
     CDS             2903..3460
                     /gene="frr"
                     /locus_tag="ACSUUC_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HHQ8054106.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3520..4374
                     /gene="cvfB"
                     /locus_tag="ACSUUC_000867"
     CDS             3520..4374
                     /gene="cvfB"
                     /locus_tag="ACSUUC_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HHQ8054107.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4383..4598
                     /locus_tag="ACSUUC_000868"
     CDS             4383..4598
                     /locus_tag="ACSUUC_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HHQ8054108.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4684..5652
                     /locus_tag="ACSUUC_000869"
     CDS             4684..5652
                     /locus_tag="ACSUUC_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HHQ8054109.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5845..6345
                     /locus_tag="ACSUUC_000870"
     CDS             5845..6345
                     /locus_tag="ACSUUC_000870"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8054110.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6348..6674
                     /locus_tag="ACSUUC_000871"
                     /pseudo
     CDS             6348..6674
                     /locus_tag="ACSUUC_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006267619.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6975..8086)
                     /gene="ald"
                     /locus_tag="ACSUUC_000872"
                     /pseudo
     CDS             complement(6975..8086)
                     /gene="ald"
                     /locus_tag="ACSUUC_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8263..8832
                     /locus_tag="ACSUUC_000873"
     CDS             8263..8832
                     /locus_tag="ACSUUC_000873"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8054111.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8900..9550
                     /locus_tag="ACSUUC_000874"
     CDS             8900..9550
                     /locus_tag="ACSUUC_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HHQ8054112.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSIDELKKVSGIGAKTIEKLKDYVTVD"
     gene            9534..11774
                     /locus_tag="ACSUUC_000875"
     CDS             9534..11774
                     /locus_tag="ACSUUC_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HHQ8054113.1"
                     /translation="MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCL
                     FFQFPWKSASKVLVICGIFGFWFVFQNWQQSQASQNLADSVEGVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLIKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSLRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPTFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            11923..12140
                     /locus_tag="ACSUUC_000876"
                     /pseudo
     CDS             11923..12140
                     /locus_tag="ACSUUC_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12173..12760
                     /locus_tag="ACSUUC_000877"
     CDS             12173..12760
                     /locus_tag="ACSUUC_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHQ8054114.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRFYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12764..13945
                     /locus_tag="ACSUUC_000878"
     CDS             12764..13945
                     /locus_tag="ACSUUC_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054115.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYFNSQTANSVS
                     LERELETRLVDRERVINEYEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKDYEFVSNDPTASSELKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEAIIPTLFVIGIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYSIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFK
                     V"
     misc_feature    14105..14236
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14252..14782
                     /gene="infC"
                     /locus_tag="ACSUUC_000879"
     CDS             14252..14782
                     /gene="infC"
                     /locus_tag="ACSUUC_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HHQ8054116.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14815..15015
                     /gene="rpmI"
                     /locus_tag="ACSUUC_000880"
     CDS             14815..15015
                     /gene="rpmI"
                     /locus_tag="ACSUUC_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HHQ8054117.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15067..15426
                     /gene="rplT"
                     /locus_tag="ACSUUC_000881"
     CDS             15067..15426
                     /gene="rplT"
                     /locus_tag="ACSUUC_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HHQ8054118.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15484..15864
                     /gene="gloA"
                     /locus_tag="ACSUUC_000882"
                     /gene_synonym="lguL"
     CDS             15484..15864
                     /gene="gloA"
                     /locus_tag="ACSUUC_000882"
                     /gene_synonym="lguL"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HHQ8054119.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16114..16914
                     /locus_tag="ACSUUC_000883"
     CDS             16114..16914
                     /locus_tag="ACSUUC_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HHQ8054120.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            16925..17863
                     /locus_tag="ACSUUC_000884"
     CDS             16925..17863
                     /locus_tag="ACSUUC_000884"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HHQ8054121.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEYAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17905..19938
                     /locus_tag="ACSUUC_000885"
     CDS             17905..19938
                     /locus_tag="ACSUUC_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HHQ8054122.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKTTNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(19999..21654)
                     /gene="pavA"
                     /locus_tag="ACSUUC_000886"
     CDS             complement(19999..21654)
                     /gene="pavA"
                     /locus_tag="ACSUUC_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HHQ8054123.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKITSMKKS"
     gene            21759..22256
                     /gene="ybeY"
                     /locus_tag="ACSUUC_000887"
     CDS             21759..22256
                     /gene="ybeY"
                     /locus_tag="ACSUUC_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HHQ8054124.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAKKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22237..22632
                     /locus_tag="ACSUUC_000888"
     CDS             22237..22632
                     /locus_tag="ACSUUC_000888"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HHQ8054125.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22649..23548
                     /gene="era"
                     /locus_tag="ACSUUC_000889"
     CDS             22649..23548
                     /gene="era"
                     /locus_tag="ACSUUC_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HHQ8054126.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23597..24421
                     /gene="mutM"
                     /locus_tag="ACSUUC_000890"
     CDS             23597..24421
                     /gene="mutM"
                     /locus_tag="ACSUUC_000890"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HHQ8054127.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24421..25026
                     /gene="coaE"
                     /locus_tag="ACSUUC_000891"
     CDS             24421..25026
                     /gene="coaE"
                     /locus_tag="ACSUUC_000891"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HHQ8054128.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            25013..26212
                     /locus_tag="ACSUUC_000892"
     CDS             25013..26212
                     /locus_tag="ACSUUC_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HHQ8054129.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRIFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26212..26361
                     /gene="rpmG"
                     /locus_tag="ACSUUC_000893"
     CDS             26212..26361
                     /gene="rpmG"
                     /locus_tag="ACSUUC_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HHQ8054130.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26401..26634
                     /gene="secG"
                     /locus_tag="ACSUUC_000894"
     CDS             26401..26634
                     /gene="secG"
                     /locus_tag="ACSUUC_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HHQ8054131.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26736..29090
                     /gene="rnr"
                     /locus_tag="ACSUUC_000895"
     CDS             26736..29090
                     /gene="rnr"
                     /locus_tag="ACSUUC_000895"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HHQ8054132.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQTLGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDTVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            29053..29520
                     /gene="smpB"
                     /locus_tag="ACSUUC_000896"
     CDS             29053..29520
                     /gene="smpB"
                     /locus_tag="ACSUUC_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HHQ8054133.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29536..30396
                     /gene="tehB"
                     /locus_tag="ACSUUC_000897"
     CDS             29536..30396
                     /gene="tehB"
                     /locus_tag="ACSUUC_000897"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HHQ8054134.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30469..31422
                     /gene="coiA"
                     /locus_tag="ACSUUC_000898"
     CDS             30469..31422
                     /gene="coiA"
                     /locus_tag="ACSUUC_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HHQ8054135.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            31441..33243
                     /gene="pepF"
                     /locus_tag="ACSUUC_000899"
     CDS             31441..33243
                     /gene="pepF"
                     /locus_tag="ACSUUC_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HHQ8054136.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALVVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            33245..33958
                     /locus_tag="ACSUUC_000900"
     CDS             33245..33958
                     /locus_tag="ACSUUC_000900"
                     /EC_number="2.1.-.-"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008171 - O-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HHQ8054137.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQRLFDATLDNSELTATLVPLG
                     DGILMLRKNVADVQLPDSE"
     gene            34025..34966
                     /gene="prsA"
                     /locus_tag="ACSUUC_000901"
     CDS             34025..34966
                     /gene="prsA"
                     /locus_tag="ACSUUC_000901"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HHQ8054138.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(35085..35426)
                     /locus_tag="ACSUUC_000902"
                     /pseudo
     CDS             complement(35085..35426)
                     /locus_tag="ACSUUC_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        10674 a         6576 c         7979 g        10262 t
ORIGIN      
        1 aagttgcttt cgtgaatacc aaaatcagcc gcaatttgtt cataagttcg atattctcgc
       61 acatattgaa gagtggccat aagaaggtct tctaggctta atttaggttt tcgtccacct
      121 tttgcgtgtt taagttgata agctgttttt aatacagcta atatctcttc aaaagtcgtg
      181 cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact tgcttcatca
      241 ttcatagaac tactatacca tattttgttt cgcaggaagt ctattggaaa gtaagaaata
      301 ttgaagctga ggctattaga agaaattgtg agcgtggtgc tattttttca ggtaaaataa
      361 aatatcacga agattcacag tttaaaggag atcactatgt tgaatgttat gctgttttag
      421 ataatacggt tatagcaaga gatagaataa cagtccctat cgatccgtta tgtggaaaag
      481 attttataga gtagcatata attgattctt aactggaata ctcactatct ctttacatca
      541 agaaaatgac taaacaggga agtttgcctt cttccctttt tttgttatac tagtagaaga
      601 aaaaatagaa agatttgtgg gagtgaaaaa gtcctgtgga ctttttcagc ctgagccaag
      661 aaactcgaaa gcttgtaagt ctgattggct ttttcaatgt gaatcttaac ttcacactcc
      721 caaagaggta ttagtgtcgt gtctcaatct tatatcaatg ttatcggtgc tggtttggca
      781 ggttctgaag cagcttacca aatcgcagag cgtggtattc cagttaaact atatgaaatg
      841 cgtggtgtca agtctacacc ccagcataaa acagacaatt ttgctgagtt ggtttgttcc
      901 aattctttgc gtggggatgc tttgacaaat gcagttggtc ttctcaagga agaaatgcgt
      961 cgcttgggtt ctgttatctt ggaatctgct gaggctacac gtgttcctgc cggtggagcc
     1021 cttgcggtgg atcgtgatgg tttctctcaa atggtgaccg aaaaagtggt caaccacccc
     1081 ttgattgaag tggtgcgtga tgaaattaca gaattgccaa cagatgttat tacagttgtg
     1141 gcgactggtc ccttgactag cgatgccctg gctgaaaaga ttcatgccct taataatggc
     1201 gatggcttct atttctacga tgcagcagcg cctattatcg atgtcaacac tatcgatatg
     1261 agtaaggtct atctcaaatc tcgttatgat aagggagaag cagcctatct caatgctcca
     1321 atgaccaagc aagagtttat ggatttccat gaagccttgg tcaatgcgga agaagcaccg
     1381 ctcaattctt ttgaaaaaga aaagtacttt gaaggatgta tgccaatcga agttatggcc
     1441 aaacgtggca ttaaaactat gctttatggc cctatgaagc cagtcggtct tgagtatccg
     1501 gacgactaca caggacctcg tgatggagaa tttaaaacac cttatgcggt tgtgcaactt
     1561 cgtcaggata atgcagctgg tagcctatac aatattgttg gtttccagac ccacctcaaa
     1621 tggggagaac aaaagcgtgt cttccaaatg attccgggtc ttgaaaatgc ggagtttgtc
     1681 cgttatggtg tcatgcatcg caattcttac atggattcac caaatcttct tgagcagact
     1741 taccgttcca agaaacaacc aaatctcttc tttgctggtc agatgacggg ggtggaaggc
     1801 tatgttgagt cggcggcttc gggcttagtt gcgggaatta acgcagctcg tctcttcaag
     1861 gaagaaagcg aggttatttt ccccgagacg acagcgattg gaagcttagc tcattacatt
     1921 acccatgccg acagcaaaca tttccaacca atgaatgtca attttgggat catcaaggag
     1981 ttggaaggcg agcgtatccg tgataagaag gctcgttatg aaaaaattgc agagcgtgcc
     2041 cttgccgact tagaggaatt tttgactgtc taattttttt gaaagaattg ttcatgatac
     2101 tataaaaatc ttagaaattg tgataaaata ggtaggatga aagaaggaga gtgaaaatgg
     2161 cgaatcccaa gtataaacgt attttaatca agttatcagg tgaagccctt gccggtgaac
     2221 gtggcgtagg gattgatatc caaacagttc aaacaatcgc aaaagagatt caagaagttc
     2281 atagcttagg tatcgaaatt gcccttgtta tcggtggagg aaatctctgg cgtggagaac
     2341 ctgcagcaga agcaggtatg gaccgtgttc aggcagatta cactggaatg cttgggactg
     2401 ttatgaatgc tcttgtgatg gcagattcat tgcaacaagt tggggttgat acgcgtgtac
     2461 aaacagctat tgctatgcaa caagtggcag agccttatgt ccgtggacgt gcccttcgtc
     2521 accttgaaaa aggccgtatc gttatctttg gtgctggaat tggttcacca tacttctcga
     2581 cagatacaac agcggccctt cgtgcagctg aaatcgaagc agatgccatc ctcatggcta
     2641 aaaatggcgt cgatggtgtg tacaatgccg atcctaagaa ggacaagaca gccgttaagt
     2701 ttgaagaatt gacccacctt gatgttatca acaaaggtct tcgtatcatg gactcaacag
     2761 cctcaaccct ctcaatggac aacgacattg acttggttgt cttcaacatg aaccaatcag
     2821 gcaacatcaa acgtgtcgta tttggtgaaa atatcggaac aacagtttca aataatatcg
     2881 aagaaaagga ataagaaaga atatggctaa cgtaattatt gaaaaagcta aagagagaat
     2941 gacccaatct caccaatcac ttgctcgtga atttggtggt atccgtgctg gtcgtgccaa
     3001 tgcaagcttg cttgaccgtg tacatgtaga atactatgga gtcgaaactc ctcttaacca
     3061 aatcgcttca attacgattc cagaagcgcg tgttttgttg gtaacaccat ttgacaagtc
     3121 ttcattgaaa gacatcgaac gtgccttgaa cgcttctgat cttggtatca caccggctaa
     3181 tgacggttct gtgattcgct tggttatccc agctcttaca gaagaaactc gtcgtgacct
     3241 tgctaaagaa gtgaagaagg tcggcgaaaa tgctaaagtg gctgtccgca atatccgtcg
     3301 cgatgctatg gacgaagcta agaaacaaga aaaagcaaaa gaaatcactg aagacgaatt
     3361 gaagactctt gaaaaagata ttcaaaaagt aacagacgat gctgttaaac acatcgacga
     3421 catgactgct aacaaagaga aagaactttt ggaagtctaa aaataaacag aaaaactcag
     3481 ttggcattgc tggctgagtt ttattcgaaa gaaggaaata tgaatacaaa tcttgcaagt
     3541 tttatcgttg gactgatcat cgatgaaaat gaccgttttt actttgtgca aaaggatggt
     3601 caaacctatg ctcttgctaa ggaagaaggt caacatacag taggggatac ggtcaaaggt
     3661 tttgcataca cggatatgaa gcaaaaactc cgcctgacaa ccttagaagt gactgccact
     3721 caggaccaat ttggttgggg acgtgtcaca gaggttcgta aggatttggg tgtctttgtg
     3781 gatacaggcc ttcctgacaa ggaaatcgtt gtgtcactcg atattctccc tgagctcaag
     3841 gaactctggc ctaagaaggg cgaccaactc tacatccgtc ttgaagtgga taagaaagac
     3901 cgtatctggg gcctcttggc ttatcaagaa gacttccaac gtcttgctcg tcctgcctac
     3961 aacaacatgc agaaccaaaa ctggccagcc attgtttacc gtctcaagct gtcaggaact
     4021 tttgtttacc taccagaaaa taatatgctt ggttttattc atcctagcga gcgttacgca
     4081 gagccacgtt tggggcaagt attagatgcg cgcgttattg gtttccgtga agtggaccgc
     4141 actctgaacc tctccctcaa accacgctcc tttgaaatgt tggaaaacga tgctcagatg
     4201 attttgactt atttggaaag taatggcggt ttcatgacct taaatgataa gtcatctcca
     4261 gacgacatca aggcaacctt tggcatttct aaaggtcagt tcaagaaagc tttaggtggt
     4321 cttatgaagg ctggtaaaat caagcaggac cagtttggga cagagttgat ttagggaggc
     4381 ttatgagaaa atcattttac acttggctca tgaccgagcg caatcctaaa agtaacagtc
     4441 ccaaagcaat tttggcagac ctcgcttttg aagaggcagc ttttccaaaa catacagatg
     4501 attttgatga ggtcagtcgc tttttggagg agcatgccag tttctctttt aacctaggag
     4561 attttgacag catttggcag gaatatctag aacactagca tttattcatt gggtttgggc
     4621 tagtaatttc tccatccctc tgctataata aaaagaaata aaaggattag agaggttctt
     4681 tatttgaagg aacattcaat agacattcaa ctgagtcatc cagatgacct gtttcatctt
     4741 tttggttcca atgaacgcca tcttcgtttg atggaagaag agcttgatgt tgtgattcat
     4801 gctcgtacgg agattgtcca ggttttggga gaagagtctg cctgtgagga agcccgtcaa
     4861 gttattcagg ctttgatggt cttggtaaat cgtgggatga ccgttggtac gccagatgta
     4921 gtcactgcga ttagcatggt caaaaatgat gaaattgaca agtttgtcgc cctttacgaa
     4981 gaagaaatta tcaaagataa tactgggaaa cctatccgtg tcaaaaccct agggcaaaag
     5041 ctttatgtgg acagtgtcaa acagcatgat gtgacctttg gaattgggcc agcaggtaca
     5101 gggaagacct tccttgcagt gaccttggca gtgactgccc ttaaacgtgg gcaagtcaag
     5161 cgaattatcc taactcgtcc agcggtggaa gcgggagaga gtcttggatt tcttccgggt
     5221 gatcttaagg agaaggtgga tccttacctt cgtcctgttt acgatgcctt gtatcaaatt
     5281 cttgggaaag accaaacgac tcgtctcatg gagcgtgaaa ttatcgaaat tgcgcccctt
     5341 gcctatatgc gtggccggac cttggatgat gcctttgtca ttctcgatga ggcgcaaaac
     5401 acgaccatca tgcagatgaa gatgttcttg acgcgtttag gctttcattc taagatgatt
     5461 gtcaatggag atatcagtca gattgacctg ccacgtaatg tcaagtccgg tttgattgat
     5521 gctcaagaga aactcaagaa catccatcag attgactttg ttcatttttc agccaaggat
     5581 gtggttcgcc atccagttgt cgctcagatt atccgagcct atgaatattc tactgaagtt
     5641 gcacacgact gattttgagg aagttcgcct gcaaaagaat atacttttga gagaggaaaa
     5701 tccagttgta taggctaaag gttttatcca aaggtctgag acaacgatta ggcacgatgg
     5761 aaagaacttt tatgtggctg atgacgatca gtgcatcttc ctgtgtcata atcacagggc
     5821 acaagaaagt aggaatttga aaagatgatt gaccaactat ctaagtatta cagttgtagg
     5881 atactaactg aaaaggatat tccaagtatt ttatctttat atgaaagtaa tcctctgtat
     5941 tttcagcatt gtccaccaga gccaaatttt gcaactgtaa aagaggacat gctttgtcta
     6001 cctgaaggta aagctaaggc tgataagttt tttgttggat tttggaatgg atctgacctt
     6061 gtggctgtta tggattttgt ctatgcctat cctgatgagg agactgtttt tattggtttg
     6121 tttatggttg atcaagccta tcagaggaaa gggattggta gtcatattgt gacagaagca
     6181 ctagcttatt ttgctaagaa ctttcgaaag gcacgtttgg cttatgttaa gggaaatccg
     6241 caatctcagc atttttggga aaagcagggt tttaaatcaa ttggatgcga ggttaagcaa
     6301 gaactctata cggttgttat cgctgaacag agcctagaag attagaaatg gcatcaagta
     6361 agaactattt ggaatttgtt ttggaacaat tatcaggatt agatgatgtg acttaccgtt
     6421 ccatgatggg ggagtatatt ctttacttcc gcggcaagat tattggcggc atttatgatg
     6481 atcgcttttt agttaaaccc gtgcaagcag tcttagataa gattgaccaa tcttcttttg
     6541 agtttccata caaaggtgcc aaagaaatga tttgagtgga agaacttgat aataagatgt
     6601 ttctataaga cctgatttta gctatgtata accaactgcc aacgcctaaa cctaaaaaga
     6661 aaaagcaagg gtgaacgaag taaaaaagaa gtctgctaag gccctgtctt tgcacgggta
     6721 aaattttata tataaaaaga agctgggact aaagagctca gcttcctttg gtttatataa
     6781 ttgtcattac aagacgaagt ggttgggcga aactctgttg actttattca atttagagtt
     6841 tcttatgcac aattgagtct ggaacgaaag tctccagttg caaagtatac agtacaataa
     6901 accaacgatg taatagctga tgacacaaag cacagtgggt aggacttgcg aagtcaccct
     6961 tttcttttca aaatttatac taaatcattg atatcagtgt agtcacgatt aagtccttga
     7021 gcaactggta ggctagtcaa gtaaccttga taagtggtca caccttgacg caagccttca
     7081 tcttcagaga ttgcttgtgc gaatcctttg ccagccaaag cttcgatata aggaagagtg
     7141 acattggtta gggcgatggt tgaagtgcgg gcaaccgcac cagggatatt ggcaacggca
     7201 tagtggagaa caccgtgttt ttcatagacg ggttcatcgt gcgttgtcac acggtcagct
     7261 gtttcgataa cgccaccttg gtcaacagca acgtcaacga tacagagcct ggacgcattt
     7321 gtttgaccat ctcatctgtc accaattccg gtgcttttgc accagggatg agaatggctc
     7381 caatcaccac atcagcatct ctcacacttg cttcaatgtt gaatgaatta gacataagag
     7441 tttgaatttg acttccaaag acttcttcta gaactgagag acgcttggca ctaatatcta
     7501 aaatagtcac ttgagcacca agaccaaggg cgatgcgggc agcatgtgta ccgacgacac
     7561 caccaccgat gatagttact tttccttttg gaacacctgg tacaccacca agtagaacac
     7621 cagagccacc agcttgctta gtaaggaagt gagctccgat ttaaacagcc atacgacctg
     7681 caacctcact cataggaacg aggagcggta gttgtccttg attgtcacga acagtttcat
     7741 aggcaattcc tgttgttttt gctgctaaca tagcatctgc taattctgga gcagcggcca
     7801 tgtgcaagta ggtgaagaga agaagatcgt cgcgcaagta accgtattca gaacttaaag
     7861 gttcttttac tttcacaacc aactctgctg cccaagcttc accagcagta gcgacaatct
     7921 cagctccttg cttttgatag tcagcatcag taaagccaga accgagacca gcatttgttt
     7981 cgataaggac acgatgacca cgactaacta agctatgaac acctgcaggt gtgagggcga
     8041 cacagttttc gttattttta atttcttttg ggattccgat taacattgag ataacctacc
     8101 tttcaattga cggtcttgtt ttggttgtca cattccagtt cataaatcaa aaatgtgacg
     8161 gtttcattgt atatgaaacc gcttcaaaaa tcaagaaaaa cttgtcatcc aaatttttta
     8221 tgctagacta gtgaaaatca agctttgatt ggttggaaaa gtatggaatc aatttttgta
     8281 aaacttgccc agtatccgtc tatagaaacg gagcgtttat tgcttagacc tgtaactttg
     8341 gatgatgcgg aagcaatgtt tgactatgcc tcggacaagg gtaatacacg ttacactttt
     8401 ccaaccaatc aaagcttgga agaaaccaag aataacattg ctcagttcta tttggctaat
     8461 cccttgggac gttggggaat agaactaaaa agcaatggtc agtttattgg aaccattgac
     8521 ttgcacaaga ttgattctgt tcttaagaag gcagctattg gctacattat caataaaaag
     8581 tattggaatc aaggattaac gacagaagcc aatcgtgctg tgattgagct agcttttgag
     8641 aagataggga tgaataagtt gactgccctt cacgataagg acaatcctgc gtcaggaaag
     8701 gtcatggaga aatcaggcat gcgtttttcc catgcagaac catatgcttg tatggaccag
     8761 catgaaaaag gccgaatcgt gacaagagtt cattatgtct tgaccaagga agactatttt
     8821 gcaaataaat aagcagttga aaagaaattt ttcgactgtt ttttcttcct cttacgaata
     8881 atctaagaga ggagaaaata tggaagcaat tatcgagaaa atcaaagagt ataaaatcat
     8941 cgtcatctgt actggtctgg gcttgcttgt aggcggattt ttcctgctaa agccagctcc
     9001 acaaacacct gtaaaggaaa cgaatttgca ggctgaagtt gcagctgttt ccaaggattt
     9061 ggtatccgaa aaggaagtga acaaggaaga gaaggaagaa ccccttgaac aagatctaat
     9121 cacagtagat gtcaaaggtg ctgtcaaatc gccagggatt tatgacttgc ctgtaggtag
     9181 tcgagtcaat gatgctgttc agaaggctgg tggcttgaca gagcaagcag acagcaagtc
     9241 gctcaatcta gctcagaaag ttagtgatga ggctctggtt tacgttccta ctaagggaga
     9301 agaagcagtt agtcaacaga ctggttcggg gacagcttct tcaacaagca aggaaaagaa
     9361 ggtcaatctc aacaaggcca gtctggaaga gcttaaacag gttaagggac tgggaggaaa
     9421 acgagctcag gacattatag accatcgtga ggcaaatggg aaattcaagt cgattgatga
     9481 actcaagaag gtctctggca ttggtgctaa gaccatagaa aagctaaaag actatgttac
     9541 agtggattaa gaacatcccc attcccctaa tttacctgag ttttttgtta ctttggtttt
     9601 attacgctat tttctcagca tcctatcttg ctttgttggg ctttgttttt ctgctagtct
     9661 gtctcttttt ccaatttcct tggaaatctg ctagcaaagt tctagtgatt tgtggaatct
     9721 ttggattttg gtttgttttt caaaattggc aacagagtca agcgagtcaa aatctggcgg
     9781 attctgttga aggggtacgg attttgcctg atactattaa ggttaatggt gatagtctat
     9841 cctttcgtgg caagtctaac ggtcgtgctt tccaagtcta ttataaactc cagtccgagg
     9901 aggagaaaga agcctttcaa gctttaaccg acctgcatga gataggacta gaagggaagc
     9961 tttcggagcc agaagggcag agaaattttg gtggctttaa ttaccaagcc tatctgaaga
    10021 ctcagggaat ttaccagact ctcaatatca aaacaatcca gtcacttcaa aagattggca
    10081 gttgggatat aggagaaaac ttgtccagtt tacgtcgaaa ggctgtggtt tggattaaga
    10141 cgcactttcc agaccctatg cgcaattaca tgacaggact cttgctggga catctggaca
    10201 ccgactttga ggagatgaat gagctttatt ccagtctagg aattatccac ctctttgccc
    10261 tatctggcat gcaggtaggt tttttcatga atggatttaa gaaacttctc ttgcgattgg
    10321 gcttgaccca agaaaagttg aaatggctga cttatccctt ttcccttatc tatgcgggac
    10381 taactggatt ttcagcatcg gttattcgca gtctcttgca aaagctactg gctcaacatg
    10441 gggttaaggg cttggataat tttgccttga cggtgcttgt cctctttatt gtcatgccaa
    10501 actttttctt gacagcagga ggagtcttgt cctgcgctta tgcttttatc ctgaccatga
    10561 ccagcaaaga aggggagggg ctcaaggctg ttactagtga aagtctagtc atctccttgg
    10621 gcatattgcc cattctatcc ttctattttg cggaatttca accttggtct atccttttga
    10681 cctttgtctt ttcctttcta tttgacttga ccttcttacc gctcttgtct attttatttg
    10741 tcctttcctt tctctatcca gtcattcagc tgaactttat ctttgaatgg ttagagggca
    10801 ttattcgctt ggtctcgcag gtggcaagga gaccgcttgt ctttggtcaa cccaacgcat
    10861 ggcttttaat cttattgtta atttccttgg ctttggtcta tgatttgagg aaaaacatta
    10921 aaggattaac agtattgagt ttattgatta caggtctctt tttccttatc aagtatccac
    10981 tggaaaatga aatcaccatg ctggatgtgg ggcaaggaga aagtattttc ctacgggatg
    11041 taactgggaa aaccattctc atagatgtag gtggtaaggc agaatcttat aagaaaatcg
    11101 aaaaatggca agaaaagatg acgaccagca atgcacagag aagcttgata ccctatctta
    11161 aaagtcgagg agtagctaag attgaccagc tgattttgac aaatacggac aaggaacatg
    11221 tcggagattt gttagaggtg accaaggctt tccatgtagg ggagatttta gtatcaaaag
    11281 gcagtttgaa gcagaagcaa tttgtggtag aactacaggc gactcaaaca aaggtgcgta
    11341 gtatgacagt aggggagaac ttgcccattt ttggaagtca gttagaagtt ctatctctaa
    11401 ggaaaatggg agatggagga cacgatgata ccctagttct gtatgggaaa ttcttggata
    11461 agcaatttct cttcacggga aatttggagg agaaaggaga gaaggacttg ctgaagcact
    11521 atccagactt gaaagtaaat gttttgaaag ctagccaaca tggcaataaa aaatcatcaa
    11581 gtccaacctt tctagaaaaa ctcaaaccag agcttactct tatctcagtt ggaaagagca
    11641 atcgaatgaa actcccccat caggaaacat tgacacgact ggaaggtatc aatagcaaag
    11701 tttatcgaac tgaccagcaa ggagctatac gttttaaggg gttggatagt tggaaaatcg
    11761 aaagtgttcg ataggaaaga taaatgttgt agattagtga aataaactaa aaatttgttg
    11821 cataataatg ataaaaatgg tataatgaaa acgtattcaa tattgaggat ataaaatcat
    11881 taaaaatcag caaaagttat tttattagtt agtttataat ctattggtct tcttcagtcc
    11941 agtgtatctg ctaagagtgt tcttaaaagt atcggtatga ttggaatatc ttctataagt
    12001 ctagtatgaa tttccatgga tatagacata ctaacgttcc gtcatggtct cgttattaca
    12061 gctattctga gtatccagtt ggttctggct ggaactacgg tcgttatgag atcataaact
    12121 attacagcgg aggctattaa ttcttaaaga gtgagaaaaa ggagggctag atatgttgca
    12181 gcttactcat gtgaccttaa aaacgcgaca agtcatcttg caagatgcgg atttcacctt
    12241 taaaaagggt aggttttatg gtcttcttgc tatcaatggc tctggaaaga cgaccctgtt
    12301 ccgtgccatt agcaatttaa ttcccataag tagtggaaat atcgcagctc ctccttcttt
    12361 attttattat gagagtattg aatggctgga tggaaactta agtgggatgg actaccttcg
    12421 tcttatcaaa aacatctgga agtcagacct aaacttgaga gatgaaatcg cctactggga
    12481 aatggctgac tatatcagtc ttcccatccg caagtattcc ttaggcatga agcaacgctt
    12541 ggtgattgct atgtattttc tcagtcaggc caaatgctgg ctcatggatg agattacaaa
    12601 tggcttagat gagtattatc gacagaagtt ttttgatagg ttagcacaaa tcgatagaca
    12661 agaacagctg gttcttttaa gttcccacta taaggaagag ttggttgata tctgcgatag
    12721 agtagtaacc attcatcagg ggcagataga agaggtttag tttatgaaag atgttagtct
    12781 atttttattg aaaaaagttt tcaaaagccg cttaaactgg attatcttag ctttatttgt
    12841 atctgtactc ggtgttactt tttattttaa tagtcagact gcaaactcag tcagcttgga
    12901 gagagagttg gaaactcgtc ttgtagaccg tgagagagtc atcaatgaat atgaagagaa
    12961 actctcccaa atgtctgata ccagctcgga ggaataccag tttgctaaaa ataatttaga
    13021 cgtgcaaaaa aatcttttga cgcgaaagac agaaattcta actttactaa aagaagggcg
    13081 ctggaaagag gcctactatc tgcagtggca agatgaagag aaagattatg aatttgtatc
    13141 aaatgacccg actgctagct ctgaattaaa aatgggggtt gaccgcgaac ggaagattta
    13201 tcaagccctg tatcccttga acataaaagc acatactttg gagtttccga cccacgggat
    13261 tgatcagatt gtctggattt tagaggctat catcccaacc ttatttgtga ttggtattat
    13321 ttttatgcta acacaactat ttgcagaaag atatcaaaat catctggaca cagctcactt
    13381 atatcctgtt tcaaaagtga catttgcaat atcctctctt ggagttggag tgggatatgt
    13441 aactgtgctg tttatcggaa tctgtggctt ttcttttcta gtgggaagtc tgataagtgg
    13501 ttttggacag ttagattatc cctactcaat ttatagctta gtgaatcaag aagtaactat
    13561 tgggaaaata caagatgtat tatttcctgg cttactctta gctttcttag cctttatcgt
    13621 cattgtggaa gttgtgtact tgattgctta ttttttcaag caaaaaatgc ctgtcctctt
    13681 tctttcactc attgggattg ttggcttatt gtttggcatc caaacaattc agcctcttca
    13741 aaggattgca catctgattc cctttactta cttgcgttca gtggagattt tatctggaag
    13801 attatctaag cagattgata atgtcgatct aaattggagc atggggatgg tcttacttcc
    13861 ttgcctgatt atccttttgt tagtggggat tctatttatc gaaagctggg gaagttcacg
    13921 taaaaaggaa gtttttaaag tttagttttc ctatagggaa gctaaagaaa aactaacata
    13981 gggagagaat caacttggtt ctctcttttt gattcgaaaa ccaaaccaaa atacaaacac
    14041 aaacttttca aaaaataact ttttatcttg acaagagcta gaaaacttgg tatcatataa
    14101 aagttgagaa aagcagaagt gagagcttct cgccttgtga cattaagttg cctggcccta
    14161 cggatgaaaa gtttcgaaga aacgctatca taacgtgcgg gcttgtatat ttacgagtcc
    14221 gctattgttt ttctctaata aaacaaaaga ggtgaaaacc atagcaaagc aagacttatt
    14281 catcaatgat gagattcgtg tacgtgaagt tcgcttgatt ggtcttgagg gagaacagct
    14341 aggcatcaag ccactcagtg aagcgcaagc tttggctgat aacgctaatg ttgacctagt
    14401 attgattcaa ccccaagcca aaccgcctgt tgcaaaaatt atggactacg gtaagttcaa
    14461 atttgagtac cagaagaagc aaaaagaaca acgtaaaaaa caaagcgttg ttactgtgaa
    14521 agaagttcgt ctaagtccaa caattgacaa gggtgacttt gatacaaaac ttcgtaatgc
    14581 acgtaagttc cttgaaaaag gaaataaagt taaggtatct attcgcttta agggtcgtat
    14641 gattacccat aaagagattg gtgcaaaagt tttagccgag tttgctgaag caactcaaga
    14701 tattgccatc atcgaacaac gtgctaaaat ggatggacgt caaatgttca tgcaattggc
    14761 gccagcgact gacaaaaaat aattgtcaga aagttaaata aaggagaaaa aatcatgcca
    14821 aaacaaaaaa cacaccgcgc atcagctaaa cgtttcaaac gtacaggttc tggtggactt
    14881 aaacgtttcc gtgcttacac ttctcaccgt ttccacggaa aaactaagaa acaacgtcgt
    14941 catcttcgta aagcatctat ggtgcattca ggagattaca aacgtatcaa agcaatgctt
    15001 actcgcttga aataatagct tgactgtaag taaacaattc taggaaatat ttggaggaaa
    15061 taaaacatgg cacgtgttaa aggtggcgtt gtatcacgca aacgtcgtaa acgtattctt
    15121 aaattagcaa aaggttacta tggagctaaa cacatcttgt tccgtactgc aaaagaacaa
    15181 gtaatgaact cttactacta tgcataccgt gaccgtcgtc agaaaaaacg tgacttccgc
    15241 aaattgtgga tcactcgtat caatgcggca gctcgtatga acggactttc atactcacaa
    15301 ttgatgcatg gtttgaaatt ggctgagatc gaagttaacc gtaaaatgct tgctgacttg
    15361 gctgttaacg atgcagtagc tttcacagct cttgcagatg cagctaaagc aaaacttggt
    15421 aaataacaac tgatgagact ggaacaggat tgtccagtct ttttaaaaat aaaggagaaa
    15481 gatatggctt caaaaatgct acacacttgc ttacgagtag aaaatcttga aaaatcaatc
    15541 gcattttatc aagatgcttt tggttttaaa gaattgcgtc gcagagattt tccagaccat
    15601 gccttcacga ttgtctatct aggtcttgag ggtgatgatt atgagttgga gttgacttat
    15661 aactacgatc acggtccgta tgtggttggt gatgggtttg cccatatcgc cctcagtaca
    15721 cctgatcttg aggcacttca tcaagaacac agtgcaaaag gctatgaagt gactgagcca
    15781 aatggtctac caggaactac accaaactat tactttgtta aagaccctga tggatataag
    15841 gtcgaagtca ttcgtgaaaa ataatttcgt gcaagttaag tagaatattc gttttctact
    15901 tgactttttt tagctgaaag agtatactaa taaaaattca acctttaagg ggagtccaga
    15961 gagactcaca aggtgtcaga taaaagaata gtgcaatttt ctagaggaga ccttttgagt
    16021 gtgctctctt gtgttgtacg attttaactg aggccttgca ctagcaaggt cttttcttta
    16081 tctggtcccc ttaaaattta aggaggaaaa gttatgaatc tcacatgtaa gaagcgtttg
    16141 ggtgtcattc ggttggaaac catgaaggtg gttgcacaag aggaaatcgc gccagcaatc
    16201 tttgaattag tcctagaagg agaaatggtt gaagccatgc gagcaggcca atttcttcat
    16261 ctgcgtgtac cagacgatgc ccatctctta cgtcgtccta tttcaatttc gtctattgac
    16321 aaggcaaaca agcagtgtca cctcatttat cggattgagg gagctgggac tgcaattttt
    16381 tcaaccttaa gtcagggaga cactcttgat gtgatggggc ctcagggaaa tggttttgac
    16441 ttgtctgacc ttgatgagca gaatcaggtt ctccttgttg gtggtgggat tggtgttcca
    16501 cccttgcttg aggtggccaa ggaattgcat gaacgtggag tgaaagtagt gacagtcctc
    16561 ggttttgcta ataaggatgc tgttattttg aaaacggaat tggctcagta tggtcaggtc
    16621 tttgtaacga cagatgatgg ttcttatggc atcaagggaa atgtttccgt tgttatcaat
    16681 gatttagata gtcagtttga tgctgtttac tcgtgtgggg ctccaggaat gatgaagtat
    16741 atcaatcaaa cctttgatga tcacccaaga gcctatttat ctctggaatc tcgtatggct
    16801 tgtgggatgg gagcttgcta tgcctgtgtt ctaaaagtac cagaaagcga gacggtcagc
    16861 caacgcgtct gtgaagatgg tcctgttttc cgcacaggaa cagttgtatt ataaggagaa
    16921 aattatgact acaaatcgat tacaagtgtc tctacctggt ttggatttga aaaatccgat
    16981 tattccagca tcaggctgtt ttggctttgg acaagagtat gccaagtact atgatttaga
    17041 ccttttaggt tctattatga tcaaggcgac aacccttgaa ccacgttttg ggaatccaac
    17101 tccaagagtg gcagagacgc ctgctggtat gctcaatgca attggcttgc aaaatcctgg
    17161 tttagaggtt gttttggctg aaaagctacc ttggctggaa agagaatatc caaatcttcc
    17221 tattattgcc aatgtagctg gtttttcaaa acaagagtat gcagctgttt ctcatgggat
    17281 ttccaaggca actaatgtaa aagctatcga gctcaatatt tcttgtccca atgttgacca
    17341 ctgtaatcat ggacttttga ttggtcaaga tccagatttg gcttatgatg tggtgaaagc
    17401 agctgtggaa gcctcagaag tgccagttta tgtcaaatta accccgagtg tgaccgatat
    17461 cgttactgtc gcaaaagctg cagaatatgc gggagcaagt ggcttgacca tgatcaatac
    17521 tctggttgga atgcgctttg acctcaaaac cagaaaacca atcttggcca atggaacagg
    17581 tggaatgtca ggtccagcag tctttccagt agccctcaaa ctcatccgcc aagtagccca
    17641 aacaacagac ctgcctatca ttggaatggg gggagtggat tcggctgaag ctgccctaga
    17701 aatgtatctg gctggggcat ctgctatcgg agttggaaca gctaacttta ccaatcctta
    17761 tgcctgccct gacatcatcg aaaatttacc aaaagtcatg gataaatacg gtattagcag
    17821 tctggaagaa ctccgtcagg aagtaaaaga gtctctgagg taaactgcaa tcaatctgtt
    17881 cttgattttt tattagtttg taatatgaat ttaggagaat tttggtacaa taaaataaat
    17941 aagaacagag gaagaaggtt aatgaagaaa gtaagattta tttttttagc tctgctattt
    18001 ttcttagcta gtccagaggg tgcaatggct agtgatggta cttggcaagg aaaacagtat
    18061 ctgaaagaag atggcagtca agcagcaaat gagtgggttt ttgatactca ttatcaatct
    18121 tggttctata taaaagcaga tgctaactat gctgaaaatg aatggctaaa gcaaggtgac
    18181 gactattttt acctcaaatc tggtggctat atggccaaat cagaatgggt agaagacaag
    18241 ggagcctttt attatcttga ccaagatgga aagatgaaaa gaaatgcttg ggtaggaact
    18301 tcctatgttg gtgcaacagg tgccaaagta atagaagact gggtctatga ttctcaatac
    18361 gatgcttggt tttatatcaa agcagatgga cagcacgcag agaaagaatg gctccaaatt
    18421 aaagggaagg actattattt caaatccggt ggttatctac tgacaagtca gtggattaat
    18481 caagcttatg tgaatgctag tggtgccaaa gtacagcaag gttggctttt tgacaaacaa
    18541 taccaatctt ggttttacat caaagaaaat ggaaactatg ctgataaaga atggattttc
    18601 gagaatggtc actattatta tctaaaatcc ggtggctaca tggcagccaa tgaatggatt
    18661 tgggataagg aatcttggtt ttatctcaaa tttgatggga aaatggctga aaaagaatgg
    18721 gtctacgatt ctcatagtca agcttggtac tacttcaaat ccggtggtta catgacagcc
    18781 aatgaatgga tttgggataa ggaatcttgg ttttatctca aatctgatgg gaaaatagct
    18841 gaaaaagaat gggtctacga ttctcatagt caagcttggt actacttcaa atccggtggt
    18901 tacatgacag ccaatgaatg gatttgggat aaggaatctt ggttttacct caaatctgat
    18961 gggaaaatag ctgaaaaaga atgggtctac gattctcata gtcaagcctg gtactacttc
    19021 aaatctggtg gctacatggc gaaaaatgag acagtagatg gttatcagct tggaagcgat
    19081 ggtaaatggc ttggaggaaa aactacaaat gaaaatgctg cttactatca agtagtgcct
    19141 gttacagcca atgtttatga ttcagatggt gaaaagcttt cctatatatc gcaaggtagt
    19201 gtcgtatggc tagataagga tagaaaaagt gatgacaagc gcttggctat tactatttct
    19261 ggtttgtcag gctatatgaa aacagaagat ttacaagcgc tagatgctag taaggacttt
    19321 atcccttatt atgagagtga tggccaccgt ttttatcact atgtggctca gaatgctagt
    19381 atcccagtag cttctcatct ttctgatatg gaagtaggca agaaatatta ttcggcagat
    19441 ggcctgcatt ttgatggttt taagcttgag aatcccttcc ttttcaaaga tttaacagag
    19501 gctacaaact acagtgctga agaattggat aaggtattta gtttgctaaa cattaacaat
    19561 agccttttgg agaacaaggg cgctactttt aaggaagccg aagaacatta ccatatcaat
    19621 gctctttatc tccttgccca tagtgcccta gaaagtaact ggggaagaag taaaattgcc
    19681 aaagataaga ataatttctt tggcattaca gcctatgata cgacccctta cctttctgct
    19741 aagacatttg atgatgtgga taagggaatt ttaggtgcaa ccaagtggat taaggaaaat
    19801 tatatcgata ggggaagaac tttccttgga aacaaggctt ctggtatgaa tgtggaatat
    19861 gcttcagacc cttattgggg cgaaaaaatt gctagtgtga tgatgaaaat caatgagaag
    19921 ctaggtggca aagattagta ctataagtga atatgatttg agtgaatagt aagttaaaaa
    19981 tcctgatttc aagtaaaatc aggatttttt catggatgta atttttttgg agtctggtgt
    20041 gacgcggagg gtcttttgtc ctgtgtaagt gacaaagccg ggttttccac cagttggttt
    20101 attgagtttt ttgacttcaa tcatatctac ctgcaccaga ttcgacaggc gcccttgaga
    20161 gaagtaggca gctaactctg ctgcgtctgt cttgactgca tcagatgggt caagatttcc
    20221 tgagatgaca acatggcttc caggaatgtc cttagcatgg aaccaaagtt cctccttgcg
    20281 ggccatttta aaggtcaatt cctcattttg aagattgttt cgtccgacat agatgatggt
    20341 tttgccatcg cttgctagat attgttctag ttttttgcgt ttctggattt tctcccgttg
    20401 tcttctgcgg ataaaacctg tttgaatcaa ttcttcacgg atttcagcga tttcttccag
    20461 tccagcttgg ttgaggacgg tttctacact ttccagatag agaatagtgg ctttggtttc
    20521 ttcaatcaaa tcagtcaagt atttgacagc ttctttgagt ttctgatacc gtttaaaata
    20581 gcgttgggca ttctggttgg gagtcagagc cttatcaagc gcaatcatga taggttggtt
    20641 ggtatagtag ttgtctagga taacctggtc ttggtcgtta ggcacttggt ggaggaaggt
    20701 tgtcagcaat tctccttttt gacgaaattc ttcagcgttg tctgtcgcca gtaattcttt
    20761 ttcctgtttt ttgagtttgt gtcggttttt ctgaagttca ttttcaacac gacgaatcag
    20821 ttcactggcc tgctgtttga cgcggtcgcg ctcagcctta tccttatagt aggtgtccaa
    20881 caaatcagaa agatttgcaa aaggctctcc cacctgattt gcaaaaggaa ctggactgaa
    20941 ggaagtctca gtcaagcatg gcttggtttc ctgattgaaa aaatttcgga aagcggaaag
    21001 tttttcacta accagtatcc tttccaattc atttgccgta tcgcgtccca gaccttgaaa
    21061 gaggctttga agattttttg ctgttagttc ttgggtttgc aggatttcaa agagcttttc
    21121 atccttgata gtaaaaggat tgagagattc tgtacttggc ggagcgatat aggtcgatcc
    21181 tggaagtaag gtgcggtagc tattttgtga aaagccgacg tgtttgataa cttcgaggat
    21241 tttatgactg cttttatcga ccagtagaat attactgtgt ttccccataa tttcgataat
    21301 caaggtagcc tggatatggt ctccaatctc gtttttattg gaaactgtca tttccacaat
    21361 acggtcattt tccacttgct caatcgactc aatcagggcc ccctgcaaat actttctcaa
    21421 aaccatgata aaggtagaag gttgggctgg attttcaaaa gtcgtttggg tcagctgaat
    21481 gcgtccaaaa actggatggg cagaaaggag caggcgatgg ctttggcgat tgctgcggat
    21541 ttgcaagacc aactcttgtt caaaaggctg attgattttc tggatgcgac cattcactaa
    21601 ttcgcttcgc aattcctcaa ctatgtggtg taaaaaaaat ccgtcaaatg acatcgttct
    21661 ctccttgtga ttgtattcca tagtattata tcaaaaaggt agaataaaat catggaaatg
    21721 tggtataata aagccaagta aagagaaacg agaagcacat gtatattgaa atggtagatg
    21781 aaactggtca agtttcaaaa gaaatgttgc aacaaaccca agaaattttg gaatttgcag
    21841 ccaaaaaatt aggaaaagaa gacaaggaga tggcagtcac ttttgtgacc aatgagcgta
    21901 gtcatgaact taatctggag taccgtgaca ccgaccgtcc gacagatgtc atcagccttg
    21961 agtataaacc agaattggaa attgcctttg acgaagagga tttgcttgaa aatccagaat
    22021 tggcagagat gatgtctgag tttgatgcct atattgggga attgttcatc tctatcgata
    22081 aggctcatga gcaggccgaa gaatatggtc acagctttga gcgtgagatg ggcttcttgg
    22141 cagtacacgg ctttttacat attaacggct atgatcacta tactccggaa gaagaagcgg
    22201 agatgttcgg tttacaagaa gaaattttga cagcctatgg actcacaaga caataaacga
    22261 aaatggaaaa atcgtgacct gatatccagt ttagaatttg ccatcacagg gatttttact
    22321 gctatcaagg aagaacgcaa tatgcgaaaa catgcagtga cggctctagt ggtcatcctt
    22381 gcaggttttg gttttcaggt gtcacgaatc gaatggctct ttctcctatt gagcattttc
    22441 ttggtggtag cctttgaaat tatcaattct gctattgaaa atgtggtgga tttggccagt
    22501 cactatcact tttccatgct ggctaaaaat gccaaggata tggcggctgg cgcggtatta
    22561 gtggtttctc tttttgcagc cttaacaggc gcattgattt ttctcccacg aatctgggat
    22621 ttattatttt aaacagtaag aggaaattat gacttttaaa tcaggctttg tagccatttt
    22681 aggacgtccc aatgttggga agtcaacctt tttaaatcac gttatggggc aaaagattgc
    22741 catcatgagt gacaaggcgc agacaacgcg caataaaatc atgggaattt acacgactga
    22801 taaggagcaa attgtcttta tcgacacacc agggattcac aaacctaaaa cagctctcgg
    22861 agatttcatg gttgagtctg cctacagtac ccttcgcgaa gtggacactg ttcttttcat
    22921 ggtgcctgct gatgaagcgc gtggtaaggg ggacgatatg attatcgagc gtctcaaggc
    22981 tgccaaggtt cctgtgattt tggtggtgaa taaaatcgat aaggtccatc cagaccagct
    23041 cttgtctcag attgatgact tccgtaatca aatggacttt aaggaaattg ttccaatctc
    23101 agcccttcag ggaaataacg tgtctcgtct agtggatatt ttgagtgaaa atctggatga
    23161 aggtttccaa tatttcccgt ctgatcaaat cacagaccat ccagaacgtt tcttggtttc
    23221 agaaatggtt cgcgagaaag tcttgcactt aactcgtgaa gagattccgc attctgtagc
    23281 agtagttgtt gactctatga aacgagacga agagacagac aaggttcaca tccgtgcaac
    23341 catcatggtc gagcgcgata gccaaaaagg gattatcatc ggtaaaggtg gcgctatgct
    23401 taagaaaatc ggtagcatgg cccgtcgtga tatcgaactc atgctaggag acaaggtctt
    23461 cctagaaacc tgggtcaagg tcaagaaaaa ctggcgcgat aaaaagctag atttggctga
    23521 ctttggctat aatgaaagag aatactaagt agaggtaggc tcatgcctgc ttcttgtttt
    23581 tacagaagga ggacttatgc ctgaattacc tgaggttgaa accgtttgtc gtggcttaga
    23641 aaaattgatt ataggaaaga agatttcgag tatagaaatt cgctacccca agatgattaa
    23701 gacggatttg gaagagtttc aaagggaatt gcctagtcag attatcgagt caatgggacg
    23761 tcgtggaaaa tatttgcttt tttatctgac agacaaggtc ttgatttccc atttgcggat
    23821 ggagggcaag tatttttact atccagacca aggacctgaa cgcaagcatg cccatgtttt
    23881 ctttcatttt gaagatggtg gcacgcttgt ttatgaggat gttcgcaagt ttggaaccat
    23941 ggaactcttg gtgcctgacc ttttagacgc ctactttatt tctaaaaaat taggtcctga
    24001 accaagcgaa caagactttg atttacaggt ctttcaatct gcccttgcca agtccaaaaa
    24061 gcctatcaaa tcccatctcc tagaccagac cttggtagct ggacttggga atatctatgt
    24121 ggatgaggtt ctctggcgag ctcaggttca tccagctaga ccttcccaga ctttgacagc
    24181 agaagaagcg actgccattc atgaccagac cattgctgtt ttgggccagg ctgttgaaaa
    24241 aggtggctcc accattcgga cttataccaa tgcctttggg gaagatggaa gcatgcagga
    24301 ctttcatcag gtctatgata agactggtca agaatgtgta cgctgtggta ccatcattga
    24361 gaaaattcaa ctaggtggac gtggaaccca cttttgtcca aactgtcaaa ggagggactg
    24421 atgggaaaaa tcatcggaat cactggggga attgcctcag gtaagtcaac tgtgacaaat
    24481 tttctaagac agcaaggctt tcaagcagtg gatgccgacg cagtcgtcca ccaactacag
    24541 aaacctggtg gtcgtctgtt tgaggctcta gtacagcact ttgggcaaga aatcattctt
    24601 gaaaacggag aactcaatcg ccctctccta gctagtctca tcttttcaaa tcctgaagag
    24661 caaaaatggt ctaatcaaat tcaaggggag attatccgtg aggaactggc tactttgaga
    24721 gaacagttgg ctcagacaga agagattttc ttcatggata ttcccctact ttttgagcag
    24781 gactacagcg attggtttgc tgagacttgg ttggtctatg tggaccgaga tgcccaagta
    24841 gaacgcttaa tgaaaaggga ccagttgtcc aaagatgaag ctgagtctcg tctggcagcc
    24901 cagtggcctt tagaaaaaaa gaaagatttg gccagccagg ttcttgataa taatggcaat
    24961 cagaaccagc ttcttaatca agtgcatatc cttcttgagg gaggtaggca agatgacaga
    25021 gattaactgg aaggataatc tgcgtattgc ctggtttggt aattttctga caggagccag
    25081 tatttctttg gttgtacctt ttatgcccat cttcgtggaa aatctaggtg tagggagtca
    25141 gcaagtcgct ttttatgcag gcttagcaat ttctgtctct gctatttccg cggcgctctt
    25201 ttctcctatt tggggtattc ttgctgacaa atacggccga aaacccatga tgattcgggc
    25261 aggtcttgct atgactatca ctatgggagg cttggccttt gtcccaaata tctattggtt
    25321 aatctttctt cgtttactaa acggtgtatt tgcaggtttt gttcctaatg caacggcact
    25381 gatagccagt caggttccaa aggagaaatc aggctctgcc ttaggtactt tgtctacagg
    25441 cgtagttgca ggtactctaa ccggtccctt tattggtggc tttatcgcag aattatttgg
    25501 cattcgtaca gttttcttac tggttggtag ttttctattt ttagctgcta ttttgactat
    25561 ttgctttatc aaggaagatt ttcaaccagt agccaaggaa aaggctattc caacaaagga
    25621 attatttacc tcggttaaat atccctatct tttgctcaat ctctttttaa ccagttttgt
    25681 catccaattt tcagctcaat cgatcggccc tattttggct ctttatgtac gcgacttagg
    25741 gcagacagag aatcttcttt ttgtctctgg tttgattgtg tccagtatgg gcttttccag
    25801 tatgatgagt gcaggagtca tgggcaagct aggtgacaag gtgggcaatc atcgtctctt
    25861 ggttgtcgcc cagttttatt cagtcatcat ctatctcctc tgtgccaatg cctctagccc
    25921 ccttcaacta ggactctatc gtttcctctt tggcttggga accggtgcct tgattcccgg
    25981 ggttaatgcc ctactcagca aaatgactcc caaagccggc atttcgagga tctttgcctt
    26041 caatcaggta ttcttttatc tgggaggtgt tgttggtccc atggcaggtt ctgcagtagc
    26101 aggtcaattt ggctaccatg ctgtctttta tgcgacaagc ctttgtgttg cctttagttg
    26161 tctctttaac ctgattcaat ttcgaacatt attaaaagta aaggaaatct agtgcgagta
    26221 aaaattaatc tcaaatgctc ctcttgtgac agtatcaatt acctaaccag taaaaattca
    26281 aaaacccatc cagacaagat tgaggtttta aagtattgtc ccaaggaaag aaaagtaacc
    26341 ctacatcttg aatctaagta gattttatgg taaaataata gggattttaa ggagtttgat
    26401 atgtataacc tattattaac cattttatta gtattatctg ttgtgattgt gattgcaatt
    26461 ttcatgcaac caaccaaaaa ccaatccagc aatgtatttg atgccagttc aggtgatttg
    26521 tttgaacgca gtaaagctcg cggttttgaa gctgtaatgc agcgtttgac agggatttta
    26581 gtctttttct ggctagccat tgccttagca ttgacggtat tatcaagtag ataagaaaat
    26641 aatgggcagg actaggtctt tgcctctttt tatttttaaa ggatgtttga gaaggtttta
    26701 cagtaaaaga aaattaaaaa atctagaaag aaaatatgaa agatagaata aaagaatatt
    26761 tacaagacaa gggaaaggtg actgttaatg atttggctca gactttggga aaagacagtt
    26821 ccaaggattt tcgtgagttg attaaaacct tgtccttaat ggaaagaaag caccagattc
    26881 gctttgaaga agatggtagt ctgacattag aaattaagaa aaaacatgag attaccctca
    26941 aggggatttt tcatgcccat aaaaatggct ttggctttgt tagtctggaa ggcgaggagg
    27001 acgacctttt tgtagggaaa aatgatgtca actatgctat tgatggtgat accgtcgagg
    27061 tagtgattaa gaaagtcgct gaccgcaata agggaacagc agcagaagcc aaaattattg
    27121 atatcctaga acacagtttg acaacagttg tcgggcaaat cgttctggat caggaaaagc
    27181 ctaagtatgc tggctatatt cgttcaaaaa atcagaaaat cagtcaaccg atttatgtta
    27241 agaaaccagc cctaaagtta gaaggaacag aagttctcaa ggtctttatc gataaatacc
    27301 caagcaagaa acatgatttc tttgtcgcga gtgttctcga tgtagtggga cactcaacgg
    27361 atgtcggaat tgatgttctt gaggtcttgg aatcaatgga cattgtatcc gagtttccag
    27421 aagctgttgt taaggaagca gaaagtgtgc ctgatgctcc gtctcaaaag gatatggaag
    27481 gtcgtctgga tctaagagat gaaattacct ttaccattga cggtgcggat gccaaggact
    27541 tggacgatgc agtgcatatc aaggctctga aaaatggcaa tctggagctt ggggttcaca
    27601 tcgcagatgt ttcttattat gtgaccgagg ggtctgccct tgacaaggaa gcccttaacc
    27661 gtgcgacttc tgtttacgtg acagaccgag tggtgccaat gcttccagaa cgactatcaa
    27721 atggcatctg ctctctcaat ccccaagttg accgcctgac ccagtctgct attatggaga
    27781 ttgataaaca tggtcgtgtg gtcaactata ccattacaca aacagttatc aagactagtt
    27841 ttcgtatgac ctatagcgat gtcaatgata tcctagctgg cgatgaagaa aagagaaaag
    27901 aatatcataa aattgtatca agtatcgaac tcatggccaa gcttcatgaa actttagaaa
    27961 acatgcgtgt gaaacgtgga gctctcaatt ttgataccaa tgaagcgaag attttagtgg
    28021 ataaacaagg taagcctgtt gatatcgttc ttcggcagcg tggtattgcc gagcggatga
    28081 ttgagtcttt tatgttgatg gctaatgaaa cagttgccga acatttcagc aagttggatt
    28141 tgccttttat ctatcgaatt cacgaggagc ctaaggctga aaaggttcag aagtttattg
    28201 attatgcttc gagttttggc ttgcgcattt atgggactgc cagtgagatt agtcaggagg
    28261 cacttcaaga catcatgcgt gctgttgagg gagaacctta tgcagatgta ttgtccatga
    28321 tgcttcttcg ctctatgcag caggctcgtt attcggagca caatcacggc cactatggac
    28381 tagctgctga ctattatact cactttacca gtccaattcg tcgttatcca gaccttcttg
    28441 ttcaccgtat gattcgggat tacggccgtt ctaaggaaat agcagagcat tttgaacaag
    28501 tgattccaga gattgcgacc cagtcttcca accgtgaacg tcgtgccata gaagctgagc
    28561 gtgaagttga agccatgaaa aaggctgagt atatggaaga atacgtgggt gaagagtatg
    28621 atacagttgt atcaagtatt gtcaaattcg gtctctttgt cgaattgcca aacacagttg
    28681 aaggcttgat tcacatcact aatctacctg aattttatca tttcaatgag cgtgatttga
    28741 ctcttcgtgg agaaaaatca ggtatcactt tccgagtggg tcagcagatc cgtatccgtg
    28801 ttgaaagagc ggataaaatg actggagaga ttgatttttc attcgtacct agtgagtttg
    28861 atgtgattga aaaaggcttg aaacagtcta gtcgtagtgg cagagggcgt ggttcaaatc
    28921 gtcgttcgga taagaaggaa gacaagagaa aattaggacg ctcaaatgat aagcgtaagc
    28981 attcacaaaa agacaagaag aaaaaaggaa agaaaccttt ttacaaggaa gtagctaaga
    29041 aaggagccaa gcatggcaaa gggcgaggga aaggtcgtcg cacaaaataa aaaggcacgc
    29101 cacgactata caatcgtaga tacgctagag gcagggatgg tcctgactgg aactgaaatc
    29161 aagagtgtac gagctgctcg aattaatctc aaggatggct ttgctcaagt gaaaaatgga
    29221 gaagtttggc tgagcaatgt tcatatcgcg ccttacgaag agggcaatat ctggaaccag
    29281 gaaccagaac gtcgtcgtaa actcctgctc cataaaaagc aaattcaaaa attggaacaa
    29341 gagaccaaag ggacaggaat gaccttagtt ccccttaagg tctatataaa agatggctac
    29401 gctaagcttc ttttaggact tgccaaaggg aagcatgact atgacaaacg ggagtctatc
    29461 aaacgtcgtg agcaaaatcg agatatcgcg cgtgtgatga aagctgttaa tcagcgataa
    29521 aaagaggaat tgaaaatgga aaaattagtt gcctataaac gcatgccttt gtggaataaa
    29581 caaacaatgc ctgaagctgt tcagcaaaag cacaatacaa aagttgggac ttgggggaaa
    29641 attactgtct tgaagggagc tctcaagttt attgaattga cagaagaagg ggaagttcta
    29701 gctgaacacc tctttgaagc aggggcagac aatccaatgg cccaacctca agcctggcac
    29761 cgagtggaag ctgccacaga tgatgtggaa tggtacttgg aattttattg taaacctgag
    29821 gattattttg ctaaaaaata caataccaat cctgttcatt cagaggtcct agaggccatg
    29881 cagacagtga aacaagggaa agctttggat ttaggttgtg gtcaggggcg taattctctt
    29941 tttctagccc agcaagattt tgatgtgaca gctgtagatc aaaatggact agctcttgaa
    30001 atcttgcaaa gcattgtgga gcaggaagat ttggacatgc ctgttggcct ttacgatatc
    30061 aattcagcta gcattgaaca agaatatgat tttatcgttt caacagttgt tctcatgttt
    30121 ctacaagcgg accgcattcc agctattatt caaaatatgc aggagaaaac cagtgttggt
    30181 ggttacaacc ttatcgtttg tgccatggac acggaggatt atccttgctc ggttaacttc
    30241 ccattcacct ttaaagaagg agaactggca gactattaca aggattggga attggttaag
    30301 tacaatgaaa atccaggcca tttgcatcgt cgcgatgaga atggcaatcg tattcaacta
    30361 cgctttgcga ccttactagc taagaaaatc aagtaaacac acatgaagat taggaatttt
    30421 cctgatcttt tttctttttt acgaatgata tagaaaagga gggaattcat gtttgttgcg
    30481 agagatgcta ggggagaatt ggtaaatgtg ttagaggata aacttgagaa gcaagcatac
    30541 acctgcccag cttgtggagg ccagctccat ttgcgtcaag gaccaagtgt acggacgcat
    30601 tttgcccata aatccttaaa agactgtgat tttttctttg aaaatgaaag tccagaacac
    30661 ctggccaata aggaatccct ctatcactgg ttgaaaaaag agacaaaggt tcaattagag
    30721 tacccgcttt cagaacttaa acagattgcg gatgtatttg taaatggcaa tctagctcta
    30781 gaagttcagt gtagtccctt gcctcagaaa gtccttaaag agcgaagtga gggctatcgt
    30841 agtcagggtt accaagtact gtggttgctg ggtcaaaaac tgtggctcaa ggagcgtttg
    30901 actcgtctac agcaaggttt tctttatttc agtcaaaaca tgggctttta tgtttgggaa
    30961 ttagacaagg aaaaacaagt tttaagactc aaatacctga tttaccagga tctccgcggt
    31021 aaactccatt atcaaatcaa ggaattttcc tatggtcaag gtagtttatt ggaaatattg
    31081 cgtcttccct ataagagaca aaaaatatct cattttacag tttctgagga caaggacatc
    31141 tgtcgctata tccggcaaca actttattat caaaatctct tttggatgaa agaacaagca
    31201 gaagcctatc aaaagggaga aaatatcctg acttatggac tgaaagaatg gtatccacaa
    31261 attcgaccaa tagtgggcaa atttttccag attgaacaag acttgactag ctattatcag
    31321 cacttttata cctattacca aaaaaatcct caaaatgatt ggcaaaagct ttatccacca
    31381 gccttttatc agcaatattt cttgaaaaat atggtagaat agaaaggatg gaggaatcta
    31441 atggtattac aaagaaatga aataaatgaa aaagatacat gggatctatc aacgatctac
    31501 ccaactgacc aggcttggga agaagcctta aaagatttaa cagaacaatt ggagacagta
    31561 gcccagtatg aaggccatct cttggatagt gcggataacc tactagaaat cactgaattt
    31621 tctcttgaaa tggaacgcca gatggagaag ctttacgttt atgctcatat gaagaatgac
    31681 caggatacac gtgaagctaa gtatcaagag tactatgcca aggccatgac actctacagc
    31741 cagttagacc aagccttttc attctatgag cctgaattta tggagattag cgaaaagcag
    31801 tatgctgact ttttagaagc tcaaccaaag ctgcaggttt atcaacacta ttttgacaag
    31861 ctcttgcaag gcaaggatca cgttctttca caacgtgaag aagaattatt ggctggagct
    31921 ggagaaatct ttggttcagc aagtgaaacc ttcgctatct tggacaatgc ggatattgtg
    31981 ttcccttatg tcctagacga tgatggtaaa gaagttcagc tatctcatgg gacttacaca
    32041 cgtttgatgg agtctaaaaa acgtgaggtt cgccgtggtg cctatcaagc tctttatgcg
    32101 acttacgaac aattccaaca cacctatgcc aaaactttgc aaaccaatgt taaggtgcaa
    32161 aattaccgtg ctaaagttcg taactacaag agtgctcgtc atgcagccct cgcagcgaat
    32221 tttgttccag aaagtgttta tgacaatttg gtagcagcag ttcgcaagca tttgccactc
    32281 ttacatcgct atcttgagct tcgttcaaaa atcttgggga tttcagatct caagatgtac
    32341 gatgtctaca caccgctttc atctgttgaa tacagtttta cctaccaaga agccttgaaa
    32401 aaagcagaag atgctttggt agtcttgggt gaggattact tgagccgtgt taaacgtgcc
    32461 ttcagcgagc gttggattga tgtttacgaa aatcaaggca agcgttcagg tgcctactct
    32521 ggtggttctt acgataccaa tgcctttatg cttctcaact ggcaggacaa tctggacaat
    32581 ctctttactc ttgttcatga aacaggtcac agtatgcatt caagctatac tcgtgaaact
    32641 cagccttatg tttacggaga ttactctatc tttttggctg agattgcctc aactaccaat
    32701 gaaaatatct tgacggagaa attattggaa gaagtggaag acgacgcaac acgctttgct
    32761 attctcaata acttcctaga tggtttccgt ggaacagttt tccgccaaac tcaatttgct
    32821 gagtttgaac acgccattca ccaagcagat caaaatgggg aggtcttgac aagcgatttc
    32881 ctaaataaac tctacgcaga cttgaaccaa gagtattatg gtttgagtaa ggaagacaat
    32941 cctgaaatcc aatacgagtg ggctcgcatt ccacacttct actataacta ctatgtatat
    33001 caatattcaa ctggctttgc ggccgcctca gccttggctg aaaaaattgt ccatggtagt
    33061 caagaagacc gtgaccgcta tatcgactac ctcaaggcag gtaagtcgga ctatccactt
    33121 aatgtcatga gaaaagctgg tgttgatatg gagaaggaag actacctcaa cgatgccttt
    33181 gcagtctttg aacgccgttt aaatgagttt gaagcccttg ttgaaaaatt aggattggca
    33241 taaaatggtt gaatcgtata gtaagaatgc taaccataac atgcgtcgtc ctgtcgtcaa
    33301 agaagaaatt gtagacttga tgcgtcagcg tcaaaagcag gtcacaggtt tcttgaaaga
    33361 attggaagac tttgcccgca aggaaaatat tcctattatt ccccatgaaa cggttgctta
    33421 tttccgtttt cttatggaaa ccatgcagcc taaaaatatt ctggaaattg ggacggctat
    33481 cggtttttca gctctcttga tggctgaaca tgcgccaaat gctaagatta caactattga
    33541 tcgtaatcca gaaatgattg gttttgccaa ggaaaatttt gcccagtttg acagtcgcaa
    33601 gcaaatcact ctcctagagg gagatgcggt ggatgtctta tctacactga cagagtctta
    33661 tgatttcgtc tttatggatt ctgccaagtc taaatacatc gtctttctgc cagaaatcct
    33721 caaacatttg gaagttggtg gtgtggttgt cttggatgat atttttcaag gcggtgatgt
    33781 tgccaaggac attatggaag tccgtcgagg tcagcgaacc atctatcgag gccttcaaag
    33841 actatttgac gcaaccttag acaattcaga actcaccgca acattagtgc ctttaggaga
    33901 tggtattctc atgcttcgta aaaatgtagc agatgttcaa ttgcctgaca gcgaatgatt
    33961 ttcagaaaaa tttaagaaaa aatagtaaaa tagatagagt aacacttatc tcaaaggagt
    34021 agacatgaag aaaaaattat tggcaggtgc catcacacta ttatcagtag caactttagc
    34081 agcttgttcg aaagggtcag aaggagcaga ccttatcagc atgaaagggg atgtcatcac
    34141 agaacatcaa ttttatgagc aagtgaaaaa caacccttca gcccaacaag tcttgttaaa
    34201 tatgaccatc caaaaagttt ttgaaaaaca atatggctca gagcttgatg ataaagaggt
    34261 tgatgatact attgccgaag aaaaaaaaca atatggcgaa aactaccaac gtgtcttgtc
    34321 acaagcaggt atgactcttg aaacacgtaa agctcaaatt cgtacaagta aattagttga
    34381 gttggcagtt aagaaggtag cagaagctga attgacagat gaagcctata agaaagcctt
    34441 tgatgagtac actccagatg taacggctca aatcatccgt cttaataatg aagataaggc
    34501 caaagaagtt ctcgaaaaag ccaaggcaga aggtgctgat tttgctcaat tagccaaaga
    34561 taattcaact gatgaaaaaa caaaagaaaa tggtggagaa attacctttg attctgcttc
    34621 aacagaagta cctgagcaag tcaaaaaagc cgctttcgct ttagatgtgg atggtgtttc
    34681 tgatgtgatt acagcaactg gcacacaagc ctacagtagc caatattaca ttgtaaaact
    34741 cactaagaaa acagaaaaat catctaatat tgatgactac aaagaaaaat taaaaactgt
    34801 tatcttgact caaaaacaaa atgattcaac atttgttcaa agcattatcg gaaaagaatt
    34861 gcaagcagcc aatatcaagg ttaaggacca agccttccaa aatatcttta cccaatatat
    34921 cggtggtgga gattcaagct caagcagtag tacatcaaac gaatagtcca aatcaatgag
    34981 tcagggaaaa aactcgactt caggaaaaaa tgaagcaaac attcccacaa taaaacgcat
    35041 agtacaaggt ttgtactgcc ccccaaaaaa gttagacaat taatttatcc gaaggattta
    35101 gttctgtatt gcacagagct aagtcctttt agttttatct taattctctt attgttgtaa
    35161 taatcaatat agtctataat ggcttgttcc aattgattaa gtgatttaaa tgtttgctca
    35221 tagccataaa acatttcgga ttttaaaatg ccaaagaaag attccatcct accgttgtct
    35281 tggctgtttc ctttgcgtga catagatgct tgaattccct tactctctag gaagcgatga
    35341 taagaatcgt gttggtattg ccagccttgg tcactatgga gaatcgtatt ctcgtagtgc
    35401 ttctctttga atgcctgttc caacattaac gatcaatcaa tttaatcatg tacctaatat
    35461 tagaattgtt tatctcaaat ttatttgaaa g
//
LOCUS       DBJKQU010000016        35135 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.016, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000016 DBJKQU010000000
VERSION     DBJKQU010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35135
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.016"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(224..586)
                     /locus_tag="ACSUUC_000903"
     CDS             complement(224..586)
                     /locus_tag="ACSUUC_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HHQ8054139.1"
                     /translation="MLEVGLNSLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            complement(856..1014)
                     /locus_tag="ACSUUC_000904"
                     /pseudo
     CDS             complement(856..1014)
                     /locus_tag="ACSUUC_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            1310..2616
                     /locus_tag="ACSUUC_000905"
                     /pseudo
     CDS             1310..2616
                     /locus_tag="ACSUUC_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2705..3394)
                     /gene="rplA"
                     /locus_tag="ACSUUC_000906"
     CDS             complement(2705..3394)
                     /gene="rplA"
                     /locus_tag="ACSUUC_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HHQ8054140.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(3602..4027)
                     /gene="rplK"
                     /locus_tag="ACSUUC_000907"
     CDS             complement(3602..4027)
                     /gene="rplK"
                     /locus_tag="ACSUUC_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HHQ8054141.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(4336..5052)
                     /gene="ldcB"
                     /locus_tag="ACSUUC_000908"
     CDS             complement(4336..5052)
                     /gene="ldcB"
                     /locus_tag="ACSUUC_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HHQ8054142.1"
                     /translation="MKKRYIVLSGLLAVTLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(5078..5539)
                     /locus_tag="ACSUUC_000909"
     CDS             complement(5078..5539)
                     /locus_tag="ACSUUC_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HHQ8054143.1"
                     /translation="MCLICQRIEWIKAGENPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KEHVTELHHMETSVKLRFLEEMSLVQEAVAKTFKAEKMNIELLGNGDAHAHWHLFPRR
                     SGDMRGHGLNGRGPVWWVPWEEMAAEDCQVKSHELEQMIKALSDELEKYTV"
     gene            complement(5541..6578)
                     /locus_tag="ACSUUC_000910"
     CDS             complement(5541..6578)
                     /locus_tag="ACSUUC_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HHQ8054144.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIELPVTTHFAFSVFEE
                     VGHGANSNIPSQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVVLA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(6676..8001)
                     /gene="brnQ"
                     /locus_tag="ACSUUC_000911"
     CDS             complement(6676..8001)
                     /gene="brnQ"
                     /locus_tag="ACSUUC_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HHQ8054145.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(8172..8459)
                     /locus_tag="ACSUUC_000912"
                     /pseudo
     CDS             complement(8172..8459)
                     /locus_tag="ACSUUC_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(8619..9197)
                     /locus_tag="ACSUUC_000913"
     CDS             complement(8619..9197)
                     /locus_tag="ACSUUC_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HHQ8054146.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFLLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(9251..10651)
                     /gene="pepV"
                     /locus_tag="ACSUUC_000914"
     CDS             complement(9251..10651)
                     /gene="pepV"
                     /locus_tag="ACSUUC_000914"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HHQ8054147.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(10664..11269)
                     /locus_tag="ACSUUC_000915"
     CDS             complement(10664..11269)
                     /locus_tag="ACSUUC_000915"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHQ8054148.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIADRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            11440..12240
                     /locus_tag="ACSUUC_000916"
     CDS             11440..12240
                     /locus_tag="ACSUUC_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HHQ8054149.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(12422..13219)
                     /locus_tag="ACSUUC_000917"
     CDS             complement(12422..13219)
                     /locus_tag="ACSUUC_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HHQ8054150.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKNQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNVIEVEDGELVNILFRKVAYDYEAELEFAK
                     SKGLPFIEMYEELRREDNYQGHNLELLASLIEKHGYVEDVKNFFDFL"
     gene            complement(13209..15056)
                     /gene="uvrC"
                     /locus_tag="ACSUUC_000918"
     CDS             complement(13209..15056)
                     /gene="uvrC"
                     /locus_tag="ACSUUC_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HHQ8054151.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     GVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNEP"
     gene            complement(15095..15796)
                     /locus_tag="ACSUUC_000919"
     CDS             complement(15095..15796)
                     /locus_tag="ACSUUC_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HHQ8054152.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(15875..17107)
                     /gene="murN"
                     /locus_tag="ACSUUC_000920"
     CDS             complement(15875..17107)
                     /gene="murN"
                     /locus_tag="ACSUUC_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HHQ8054153.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQDLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(17112..18332)
                     /gene="murM"
                     /locus_tag="ACSUUC_000921"
     CDS             complement(17112..18332)
                     /gene="murM"
                     /locus_tag="ACSUUC_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HHQ8054154.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQTIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMIWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(18444..19223)
                     /locus_tag="ACSUUC_000922"
     CDS             complement(18444..19223)
                     /locus_tag="ACSUUC_000922"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHQ8054155.1"
                     /translation="MAVMKIEYYSQVLDMEWGMNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(19292..20953)
                     /locus_tag="ACSUUC_000923"
     CDS             complement(19292..20953)
                     /locus_tag="ACSUUC_000923"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0004534 - 5'-3' RNA exonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HHQ8054156.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(21128..23350)
                     /gene="recJ"
                     /locus_tag="ACSUUC_000924"
     CDS             complement(21128..23350)
                     /gene="recJ"
                     /locus_tag="ACSUUC_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HHQ8054157.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIAFMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGMVQEIYDFLMEKE
                     "
     gene            23627..24385
                     /locus_tag="ACSUUC_000925"
     CDS             23627..24385
                     /locus_tag="ACSUUC_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054158.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            24396..25190
                     /locus_tag="ACSUUC_000926"
     CDS             24396..25190
                     /locus_tag="ACSUUC_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HHQ8054159.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSD
                     YGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            25203..25880
                     /locus_tag="ACSUUC_000927"
     CDS             25203..25880
                     /locus_tag="ACSUUC_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHQ8054160.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            25890..26549
                     /locus_tag="ACSUUC_000928"
     CDS             25890..26549
                     /locus_tag="ACSUUC_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHQ8054161.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALVEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            26807..27997
                     /locus_tag="ACSUUC_000929"
     CDS             26807..27997
                     /locus_tag="ACSUUC_000929"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin reductase family protein"
                     /protein_id="HHQ8054162.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTIKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(28318..29199)
                     /locus_tag="ACSUUC_000930"
     CDS             complement(28318..29199)
                     /locus_tag="ACSUUC_000930"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HHQ8054163.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(29340..30668)
                     /gene="vncS"
                     /locus_tag="ACSUUC_000931"
     CDS             complement(29340..30668)
                     /gene="vncS"
                     /locus_tag="ACSUUC_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HHQ8054164.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMYLDAQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(30665..31321)
                     /gene="vncR"
                     /locus_tag="ACSUUC_000932"
     CDS             complement(30665..31321)
                     /gene="vncR"
                     /locus_tag="ACSUUC_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HHQ8054165.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(31370..31453)
                     /gene="pep27"
                     /locus_tag="ACSUUC_000933"
     CDS             complement(31370..31453)
                     /gene="pep27"
                     /locus_tag="ACSUUC_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HHQ8054166.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(31633..33012)
                     /gene="vex3"
                     /locus_tag="ACSUUC_000934"
     CDS             complement(31633..33012)
                     /gene="vex3"
                     /locus_tag="ACSUUC_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HHQ8054167.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(33064..33711)
                     /gene="vex2"
                     /locus_tag="ACSUUC_000935"
     CDS             complement(33064..33711)
                     /gene="vex2"
                     /locus_tag="ACSUUC_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HHQ8054168.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(33724..35001)
                     /locus_tag="ACSUUC_000936"
     CDS             complement(33724..35001)
                     /locus_tag="ACSUUC_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8054169.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT        10032 a         7990 c         6488 g        10625 t
ORIGIN      
        1 ataaactaac ctcctcatta ttagcaaggc ttctactgat tataacctaa ttcttagact
       61 acttcaagac taactgtcca ataataatct acagataaat catccactct taatcaaatt
      121 ttattcaatc catctactca ttcccaaaag gttgctgtat aatgcaagac atttttctta
      181 ctgcttttac ttttccttac cctcaattta gtgagctaat aaattattct tcttcaaaag
      241 gttgagattt atctagtaac tctaaaacat taatggtagg tagcaacatt gcttcactgc
      301 tatcaattgc cgaaactatt gaaacaatag aacgtaaata aggataaaga atagcagtac
      361 catttacgta tagaatatcg gtgatatttt catctatatt tatttcaaaa tatcctatta
      421 cagttacaga tatttttttc atggcatctt tgtcaactaa agaaacacta agttttacgg
      481 ctccatgact ataatcatct gtatgaccaa ccttaactat gggatataat atatcgaagg
      541 taaatgtgaa caaactgatt agggaattta aaccaacttc taacaatgtg ttatactcaa
      601 tgaaaaccaa agagcagact aggaaactag cctcaggttg ctcaaaacac tgttttgagg
      661 ttgtggatag aactgacgaa gtcagtaacc atacgcacgg caaggcgacg ttgacgtggt
      721 ttgaagagat tttcaaagag tattagaaag ctcgatggac tattccagat tcattccact
      781 agatttcgaa atcgagtagg ggataatctc tagcccctct cacaccaccg tacgtgccgt
      841 tcggcatacg gcagttcaac taacttttaa cgcatgtcgt tcaaggtaat aatccaaaca
      901 cgaaaccagt tcacgttttt caaggactgg ttttgatata gcacgtttaa gtaccgactt
      961 ctgagctact aattgatagt ggtcgcccca gccagatacc ttatccgcta tataggcctt
     1021 attatcacgt tcctgttcgt agagccacga tttcgctatc ccttcctctg acgattctta
     1081 tttcctgcgt cagacttggg aatcgctatt gggttcaccg gtagcaggtg cccactgagg
     1141 acttacacct cagatatacg acatgcccgt cgtacatcaa aaaaagggct ctataatatt
     1201 tgtagtgggt aaccccccta tagatattat ggagcctatt ttgtgtagaa aaaaagtccc
     1261 atatgaccta taatgaaaag cgacaaaaca actcattaga aagattcata tggaacaatt
     1321 acattttatc acaaaattac tagacattaa agaccctaat atccagattt tagacatcat
     1381 caataaggat acacacaagg aaatcatcgc caaactggac tacgacgccc catcttgccc
     1441 tgagtgcgga aaccaattga agaaatatga ctttcaaaga ccttctaaaa ttccttatct
     1501 tgaaacgact ggtatgccta ctagaattct ccttagaaaa cgccgtttca agtgctatca
     1561 ctgttcaaaa atgatggttg ctgagactcc cctggtaaag aaaaatcacc aaatccctcg
     1621 tatcatcaac caaaagattg ctcaaaagtt aattgaaaag atttctatga ctgatattgc
     1681 ccatcagctt tccatctcaa cttcaactgt tattcgtaag ctcaatgatt ttcactttaa
     1741 acatgatttt tcttgtcttc ctgagattat gtcttgggat gagtatgctt ttacaaaggg
     1801 aaagatgagc ttcattgcgc aagattttga taatcttaat attatcacta ttcttaaagg
     1861 cagaacacaa gctgtcatcc gaaatcactt tcttcgctac gatagagctg tccgatgtcg
     1921 cgtcaaaatc attactatgg atatgtttag cctttactat gacttggcta aacagcttcg
     1981 ctttcaaatt tctaggctca ggctgaaaca gtctcccaga ctgtttcact cccgaatgct
     2041 aaaatcgttc ttgaacgctt tcacattgta caacatctta gccgtgctat gagtcgtgtg
     2101 cgtgtccaaa tcatgaatca gtttcatcga aaatcccatg aatacaaggc tattaagcgc
     2161 tactggaaac tcattcaaca ggatagccgt aaactgagtg ataagcgatt ttatcgtcct
     2221 acttttcgta tgcacttaac caataaagag attttaaaca agcttttgag ctattcggaa
     2281 gacttgaaac accactatca gctctatcag ctcttgcttt ttcacttcca gaataaggaa
     2341 ccagagaaat ttttcggact tattgaggac aatcttaagc aggctcatcc tatttttcag
     2401 actgtcttta aaaccttcct caaagataaa gaaaagattg tcaacgccct tcaactacac
     2461 tattctaatg ccaaactgga agcgaccaat aatctcatca aacttatcaa gcgcaatgcc
     2521 tttggttttc gaaactttga aaacttcaaa aaacggattt ttatcgctct gaatatcaaa
     2581 aaagaaagga caaaatttgt cctttctcga gcttagcttt ttttcaaccc actacagttg
     2641 acaaagagcc aaaaaaagtt gagacatagc gtcttcaact tttttacatt actttaacta
     2701 ctgattaaag tgagtttaca tcaactttga taccaacacc ttgagtagtt gtgatagtca
     2761 agtttgttac gtaagttcct ttagctgtag ctggttttgc tttttggatt gtttcgttga
     2821 aagctttaaa gttttcaacc aatttttcag cttcaaatga tactttaccg atgattgctt
     2881 gaacgttacc tgcacggtca gcacggtaag tgattttacc acctttagac tcttcaactg
     2941 ctttagcaac atccattgtt acagtaccag ttttagggtt tggcatcaag ttacgtggtc
     3001 caaggacacg tccaagacgt ccaacaagag ccatcatatc aggtgtagcg ataactacgt
     3061 cgaagtccaa ccaaccgtcg ttgattttag caacaaggtc atcttcacca acaaagtctg
     3121 caccagcagc ttttgcttct tcagcttttg caccacgtgc gaaaacaaga acacgtgaag
     3181 ttttaccagt accgtttggc aataccattg ctccacggat ttgttggtca gcttttttaa
     3241 cgtcgatgtt caagttgtaa gcaacttcta cagttgcgtc aaattttgca aagttagttt
     3301 cttttgcaag tgctacagct tcttctacgc tgtatgcttt tgtgctgtcg attttctcaa
     3361 gagcagcacg aagttgtttg ctttttttag ccattttcta ttctccttgt aagtggttca
     3421 atcgattttc atctcccacg tcacttctcg aaatgatgaa gtcttgcggg ttttcagtct
     3481 actatttttc tcttcctacg gccttaagct cccttgctgt acccaagtac aagcctcagt
     3541 cacttgccta gtatgaaaag caactaatag actgctgtga gattttctac tgtgttattg
     3601 attagtcaac aacagtgaat cccatagaac gagcagtacc ttcgatcata cgcattgcag
     3661 actctacgtt tgctgcgttc aaatctggca tcttagtttc tgcaatttct tgtacttgtg
     3721 cacgagtaac tgtagcaact ttagttttat taggtgtacc tgatcctttt tcaacacctg
     3781 cagctttttt caaaagaaca gcagctggtg gtgttttcgt aacgaaagta aatgatttat
     3841 cttcgtaaac tgagataaca actggaatga tcataccagc ttggtcagct gtacgagcgt
     3901 tgaactcttt tgtgaatccc atgatgttga taccagcttg accaagagca ggtccaaccg
     3961 gtggagctgg tgtagcttta ccagcaggga tttgcaattt tacaagtttt tcgacttttt
     4021 tagccatttt taaatcctcc tttgtggttt tggcggtaat tagagatttt tacctcccac
     4081 aagtatgttt ttcgcatacc cattcattat acactattta tctggaattg caagagaaaa
     4141 gtttattttt tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggctgc
     4201 tcaaagtaca gctttgaggt tgcagataaa actgacgaag tcagctcaaa acactgtttt
     4261 gaggttgtga atagaaccga cgcagtcagt aggtaagacg acgctgacgt ggtttgaaga
     4321 gattttcgaa gagtattaat cgacgtagtc tccgccttca aagccatagt attcttccaa
     4381 actgagacca cttgcagcaa tttctttagc ttcttttcct acataacgca ggtgccattc
     4441 ctcagccata tagcctgttt ccttttcctt gcctttgaga taacggacaa caaagccata
     4501 atcagctgca tgatccaaga gccattgggc tgctttttct tctgtcacca aatcaccatc
     4561 agtcccaatc acatcaaagg ccaagcctgt ctggtgttcg ctatagccag gacgggcaga
     4621 gtaacggtca gctgctgcct ttccatcttg gttgacataa tcttgataga gcttggtctg
     4681 agtttcataa cttctaaaac cactgtaatg atcactaata gggaaacctg cctcttgcat
     4741 cgctttgatg agtttgacca actcagcctt ggctgttgga ttttccccgg gattatagtc
     4801 tttcgacaaa ggataatgtt tattggctac gatgatttcg tcgtattttc cttggatgct
     4861 gtagtaatca cctttattga ccacttctgc ttttttctgg gcagcccctt gagacttact
     4921 gccgactgtc ccatcagctt tggctgtctg ttctgtctta gctgtgccat cttcattttt
     4981 tgctttttct tgtgaacaag ctgctagggt tactgccagc aaaccagata aaacgatgta
     5041 tctttttttc attttttctt cctctattct tcctctctta gaccgtgtac ttctctaatt
     5101 catcggataa ggctttaatc atttgttcca actcatggga tttcacttgg caatcttctg
     5161 ccgccatttc ttcccagggc acccaccaga ctggaccacg gccattcaat ccatgacccc
     5221 tcatatcacc tgaccgtctt ggaaagagat gccagtgagc gtgggcatct ccatttccta
     5281 gaagttcaat gttcatcttt tcagctttaa acgttttggc aacagcttct tggaccaaac
     5341 tcatttcctc tagaaaacga agttttacag aagtctccat atgatggagt tctgtgacat
     5401 gctcttttgc tagaaataag gtatagccct taaagtattg gtggtctcca ataacaacat
     5461 agcctgtttc tagttctttt acaaagtagg gattttcccc tgccttgatc cattcaattc
     5521 tttgacaaat caagcacata ttagtctacc aatgcactct taagataagc atcgaccata
     5581 cgctcagtcg ccactactga atcaatgtgt gttcgttcgt aagagtgact tgactcaata
     5641 ccagctccaa ggagagcatg ctttacttct gctcctgcag acatagctgc cgaagcatcc
     5701 gaaccgtaaa atggataaat gtcgagctta aatggaatat cttgctcctt cgccaaaact
     5761 accaagtgtt gacggaagtc atagtgatag ggacctgaag cgtccttgac acagatagac
     5821 actgtatact catccgtctg ctggtcatct cccatagctc ccatatctac agccagatat
     5881 tctactacct gacttggaat attggagttt gcaccgtggc ccacctcttc gaagactgaa
     5941 aaagcaaaat gagttgttac tggcaattca atcccctctt ccttataaac acgaagaaga
     6001 ttgagcaaaa ttgctgcgct gaccttgtca tccaagtggc gagacttgat aaaaccagtc
     6061 tctgtcacga cagttcgtgg atcgaagctg ataaaatcac cgacctcaat cccaagagca
     6121 cgagtttctt tttcattgct tacttttaca tccaaacgca cttccatatt gtcctgcgtg
     6181 cgttctgcag ttcctgcatc cttgtagaca tggcaagaag tttggtggat gaggatggtt
     6241 cctgatacct tttgacctgt gctagccaca tgaacggtac agttttcacc ttcaatcatg
     6301 ttccaaggaa aaccaccgat acggtccaat ttaagacgac catctggttt gacagcacga
     6361 acaatagcac ccagcgtgtc cacatgggca gtcacatagc gatgttgctc atcattttga
     6421 cctttgatgg tcacattgac accacccttg gctgtgcgaa ctggctggta accaaaacct
     6481 tctagagtct tgactaaata attcgaaatt tcacgagtga agcccgttgg cgatgcgatg
     6541 gctgtcagtt ctttgatata ttctactgtt tgattcattt cttcacctct ttcgctacct
     6601 attataacac atttatcatc ggataaaaaa agaaaatcac tcctgtagac ttggctacaa
     6661 aagtgattta agtgattatt ccatttcaaa aacatcgctt tcttgcttgt ttggtagaac
     6721 caatgagagc aagattccaa caatggctgg caccaaccat gggagagatg ccttggcaaa
     6781 aggaagaacg ctaacaagat ttgcaagaaa ctcaacctta aacgagcttc ctagtacgct
     6841 tgcaatggca ataactgtaa ccacagcaat tgtcaactgc atacctggtt ttgaaagggc
     6901 aacaaatttg ttgacaatga caatcataac gatagcaatc gtgattgggt acaagataac
     6961 cagtactgga attgagtact tgataatcgc atcaagaccc aaattggcaa tagcaaatcc
     7021 aatcaaggta aaggctgtcg cataaacctt gtagctgatt tgtgggaagc gctcattaaa
     7081 gaactcagct gttgacacaa tcaaaccaac agtcgttgtg aagcaggtta cggtaaccat
     7141 agctgcaagg aagagttgag ctgttgagcc aaagatttct tgagtggctt gtgacaagat
     7201 gtaaacacct ggtgttccac ccttcatcgc ttcagctggt actgggaaat gatttccaag
     7261 aaaacctaaa ccgatgtaaa gagcgctgaa ggcaagggca acaacgatac caacaaccca
     7321 aatagttgaa atgtattctt tcttacttga aaatccaagt tgtttcaagg tttgaactgc
     7381 gattacgcta aaggccactg aggcaagggc gtccaaggta ttgtaacctt ctaggaaacc
     7441 tgtaccaaag gcagaagctt gataagcagc tgaagcagct tgaggacttg ttccaccata
     7501 tttgatagct cccagaacga ccaagataac aatcaaaatt gcaaagactg gcgttaaaat
     7561 acgtccaatg cggtctaaga tttttgatgg attaagcgaa atcaaatagg ctgccgcaaa
     7621 atacagaacc gtaaatacaa tcaagccaag tcctttattt gcatccgaca aaagggggct
     7681 aatccctact tcgtaagctg ttgtagcagt acgtggggta gcaaagaatg gaccgattga
     7741 caagtaaaga actgagaggt aaagagtcgc aaaccaaggc gctatcttcg ttgaaatctc
     7801 gtagatatat cctttaggat ttagcgttcc aataataagg gtcaagacgg cgataccaac
     7861 gcctgaaaag acaaaacctg cgatggcagg aagaaaatgt tctccagata gagcacctag
     7921 agaaggcgga aaaatcaagt tccccgcacc aaaaaatatt ccaaacagga gcaaacctgt
     7981 tagggtacct tttttagcca taaaaatctc cttcatattt ataaaatact gacctagtat
     8041 accacgatta ggagtctgaa aaaagcatca cgaggcaaat attaaatgtt ttcaattttc
     8101 ttaaaaataa gaattatcta aaaataaaac tctcctaccc agtccacacc aagtaggaga
     8161 aatgcaaaat tttaaagttc ttcaaaggct aacatgccac cctggacatt gataacgtta
     8221 taaccttgtt ctaacaggaa ttggcaagca cgcgccgatc tcattccaga tttgcaaata
     8281 atataatgca agcgatcttt gtccaattaa tcataactat cagccaattg actaagcggt
     8341 aggttgtggg taccttctaa atgaagagct gcaaactcat ccacttctct cacatccact
     8401 agagaaagct ggtcgttttg gtaaagctga taaaatgcgt caaaggctat ttctttcatt
     8461 ctttttcttc taatactctc cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgtg
     8521 cgtatgttac cgacttcgtc agttttatct gcaacctcaa agctgtactt tgagcagcct
     8581 acgactagct tcctagtttg ctctttgatt ttcattgact ataaaatggt tttaattctt
     8641 tttttcaaat ctggcactac ttctgcctca aaccaaggat ttttggccat ccagatttga
     8701 tttcgtggtg atgggtgaac tagcagaaaa taggctggca gatagtcttt atagtgtttc
     8761 accctctccg ttaccttccc actgattttc tcctgtaaat agtaggcttg ggcatattgc
     8821 ccaatcaaga gggttaactg aatatcaggc aattcctgta agagctgcgg atgccatttt
     8881 tctgcaaaac ctgtacgagg cggaagatca cccgacttgc catgtcctgg aaagtagaaa
     8941 tccataggca aaacagcaaa ataacctgaa ttgtaaaagg tatcttcatc tacacctagc
     9001 cagtcccgca agcggtcacc acttttatct ttccagtaaa ggcctgcttc ttgagtttta
     9061 agtcccggag cctgaccgat gatattgatg cgagcagttt ttggcgctgc aaagagaggc
     9121 tcaatgccac gctctgtata gctggcattc tgcgaatccg ccatgatagc ctgtttgatt
     9181 ctttcgattt gagacatcta ctttccctcc aaaaagaagt ccaagcataa gatctcagac
     9241 ttctatcgtt ttatttgatc aattcgtaaa tagcttcggc ataaattgct gctgctcgga
     9301 agagatcgtc caaggcaata aattcattgg cttggtgcat agtatcaatt gagtctggga
     9361 acatagcacc ataggcaact ccgcgctcta acaagcgacc aaaggttcca ccaccgatga
     9421 cttgctcatg accttgtagg ccagtttgtt tttcatagac attcaacaag gtttgcacaa
     9481 gtggatcttc cattggcaca tagtgagggg tatgaccatg ttctgataga ctgacagaag
     9541 caactggcaa gttttctagg attgacttga tttgttctgg acttgttcct tttggatagc
     9601 ggatgttaag ggcaatggta ttatcagcac ttgtttcatc gaagcggaag acgccggcat
     9661 tcatagaaag agcccccatc ttttcatcca catgagcaat cttgagattt tcaccctcat
     9721 gatcgttcaa gagaatttta cctgcgatgt caaggtagtc tttggctgga ccagcaaagc
     9781 caaactggct gaggaagagg gcaaggtaag ttgcgccatt gacacctgaa gcaggcatag
     9841 caccgtgggc tgatttacca atgatcgtca ccttgtattt gccagcttct tcttggagtt
     9901 ctcctctaag tttgtgttct gcaacaaagg catctagttt agcttgcaag tcagccaaat
     9961 cacctgaaac gactgctgtt gctgattctg gtaccatatt ttcacgtaaa ccacctgtaa
    10021 agctgtgaag acgggcagca cctgtatttt ctcctgcaaa gtggaggtat tccgtgatat
    10081 ttcctttttc accattgatg attggaaatt cagcatctgg tgagaaaccg aaatctggtt
    10141 tggcaagtcc tacgtgctca aagtagtagt ccatgtctgc ccagcctgat tcttcgtctg
    10201 ttccaacgat gaagcgaact ttcttagaag ttggaaggcc taattctttg atgattttca
    10261 aaccatagta gcaagctgtt gtaggtccct tgtcatctga agcaccacgc gcataaaggc
    10321 gaccatcttt gatagttggt gtgtaaggat ctgtatccca accgctacca gctggaacca
    10381 catccatatg ggcaaagatt ccgagaactt cttctccatc accaaactca aaatgtcctg
    10441 catagttatc aacattttta gttggataac catcacggtc tgcgatttca aggaattttt
    10501 ccaaggcttt tactggacca ggtccaaatg gatgttgggc atcagccttg ctatcatcac
    10561 gttctgagtt gatttccaaa aggctaaaca agtcagccaa gaggtcttct ttgcgttttt
    10621 ctacttctgc tgtaaaatca attgctatca ttttttcttc ttcctatctt ttttcgatga
    10681 tttcatctac tggcaagcgg tagcttggtt ccaatttgtc gtctgtgtaa cccactgtga
    10741 tcaagagttc tgggcggaaa cggtctgcga tttccaaaac ttcattaact tttgatttgt
    10801 caaaaccaag gataatattg gaaccaattc cttggtctgt aagagcgaga accaagttca
    10861 tagcaaccaa acctgcattg agtgctaggt agtcgctgac ttgttgttca ttgtagcgtg
    10921 caaattcagc tggcaaattt ttcatgaagt attgaagttg ttcttctgag aaattgttag
    10981 caccaccaac tcgggcaatc ttacgagcgc gtttggcaag gtctgtatct gtaaataggg
    11041 caatggttac aggtgctgat gatacctgtt caaaattgga accataagct aactttgcca
    11101 gttcagcatt tttctcacgt accaccacaa atttccaagg ctggctgttg tgggcgcttg
    11161 gcgccaaggt tgcaatttcg atagccgtac gcacatcttt gggatcaaca ggcttatcag
    11221 taaaatgctt ggtcgcatga cgttttttat ttaattcaag aaatttcata atcgatttcc
    11281 ttttctaatt ctactgcttc cattctacca taatttgaaa gagcttgcag ggatttttca
    11341 tgattaagtt tttctatcac agacataaaa gatatatatt ggtttatcag gaaagtttct
    11401 gataaactag caagtacttt acatttgaat ggagacagta tgaaaaaatt tagcctatta
    11461 ctagctatcc taccattttt ggttgcctgt gggaatcaag ctacacccaa agagactagc
    11521 gctcaaaaga caatcgtcct tgctacagct ggcgacgtgc caccatttga ctacgaagac
    11581 aagggcaatc tgacaggctt cgatatcgaa gttttaaagg cagtagatga aaaactcagc
    11641 gactacgaga ttcaattcca aagaaccgcc tgggagagca tcttcccagg acttgattct
    11701 ggtcactatc aggctgcggc caataacttg agttacacaa aagagcgtgc tgaaaaatac
    11761 ctttactcgc ttccaatttc caacaatccc ctcgtccttg tcagcaacaa gaaaaatcct
    11821 ttgacttctc ttgaccagat cgctggtaaa acaacacaag aggataccgg aacttctaac
    11881 gctcaattca tcaataactg gaatcagaaa cacactgata atcccgctac aattaatttt
    11941 tctggtgagg atattggtaa acgaatccta gaccttgcta acggagagtt tgatttccta
    12001 gtttttgaca aggtatccgt tcaaaagatt atcaaggacc gtggtttaga cctctcagtc
    12061 gttgatttac cttctgcaga tagccccagc aattatatca ttttctcaag cgaccaaaaa
    12121 gagtttaaag agcaatttga taaagcgctc aaagaactct atcaagacgg aacccttgaa
    12181 aaactcagca atacctatct aggtggttct tacctcccag atcaatctca gttacaataa
    12241 cactcttcga aaatctcttc aaaccacgtc agctttatct gcaacctcaa agctgtgctt
    12301 tgagcaacct acggctagct tcctagtttg ctctttgatt ttcattgagt ataagatata
    12361 ctaaaagcga tgggatcagc caatcgcttt tttagtttgc attggttatt ttaggaaact
    12421 cttacaaaaa atcaaaaaaa ttcttcacat cctctacata cccatgcttt tctattaagc
    12481 ttgctaatag ttccagattg tgcccctgat agttatcttc acgacgtagt tcttcataca
    12541 tttcgataaa gggaagcccc ttggatttgg caaattctaa ctcagcctcg taatcataag
    12601 cgactttacg aaataggata tttaccaatt ccccatcttc aacctctatc acgttaaaat
    12661 agggcatgcc aatcgaccct ggattgatga tttgttgccc ttgactacca taacgaagca
    12721 actgcttgtg aacatgacca taaactgcca cgtccgtttc cgcatctagc agttggtcaa
    12781 atttctctgt atcattctca actagcaagt caccaccata gtttttgtca ggtaaattat
    12841 gagagataga aaagcgcaat ccgtcaattt ctttcttttc cagcaaaggc aagcttcgta
    12901 gccagacaat cgttgcagga tccattcgct ccatcaaata ctgtgtcata cgcaagagct
    12961 gaacttcctg tgggtcttct aagccatatt gcccatctaa agcctcaagg acacgatcat
    13021 cccaattgcc tcgaacactt gctgtgatag gaaggtcctt tagcagggcg actaagtcat
    13081 ttgcgcctgg accaggaaga aaaatatctc ccagaagcca gtattcactg actccttgat
    13141 ttttagcatc tgcaatcact gcttctagcg ccgtcgcatt gccatgaata tctgataaaa
    13201 ttgcgatttt atggttcatt gtggtttcct tctgtttggt aatctactct ttcttccgcc
    13261 acttgaagca agatttctgt ttcctgcggg ttcaactttc tttgcacagc ctctgctact
    13321 gctcttggta ctccaacttc gacaatctca tccacaccgg cttccttgat tttggtcaga
    13381 gacttgaagt gcctcatgag attttgcttg cgtttaggtc ccagaccatc aatcccatcc
    13441 aattgagatg agaaagaatt tttggagcgc agttggcggt ggaaggtaat ggcaaagcgg
    13501 tgcacctcat cttggatgcg ttggaggagg aaaaattcct gagaattgcg agacaagtcc
    13561 accacctcaa gcggatctcc aaagagcagt tcatgggttt ggtgcttatc attcttttgc
    13621 agacctgcaa ttggaatatc caagcccagt tcttcttgga tgacttgctt agcaatattg
    13681 acttgacctt gccccccatc aatcacaatc aaatctggag gagtcaaagc ctcacgctgt
    13741 actcgaccat agcgtctgcg aatgacttct ctcatactag catagtcgtc cggcccaaca
    13801 acggttttta tcttgtactt acggtaatct tttttacttg gcctgccgtt aacaaagacc
    13861 accatggctg aaacaggact ggtccccatg atgttggagt tatcgaagga ctcgatgcga
    13921 actggagtcg gaatttggag caaacgtcct agattttcaa tagctccttg ggtcttttcg
    13981 actgattttt ctagcaggtt aaatttctgc tccagactaa cacgtgcatt ttttatggct
    14041 agattgacca gctgtttttt ctctccacgt tggggtttga gaatcttggt atccaccaaa
    14101 gccttgacag cttcttcgtc aatatcctgc ggaatcagta cctcattggg aactaggtga
    14161 gatttttctt gatagaattg tcccacatag gtcaagaaat cctcatctgg atcattgaag
    14221 taggggaaga gattgacatc gcgctcgatg agcttgccct gacgaacaaa gaaaacctgc
    14281 acacacatcc agcccttatc cacatagtag ccaaagacat cgcgattttg gagatcctta
    14341 gccatgaccc gttgcttggt tcgaagtgtt ccaatggcct gaatcaggtc acggtattcc
    14401 gctgcccgtt caaactccat actttgtgct gttactgcca ttttactctt gagatcatcg
    14461 atgattttgt catcctgacc tttcagaaaa tcagacacct cctgggccat ggacttgaaa
    14521 taggcctcgt cattcttaca gatggtgtgg gccatacatt ggccgatatg gtagtaaaaa
    14581 cagaccttag agggcgggtt ggtacatttt cgaaaaggga aaatcctatc tagaagtcgc
    14641 ttgatttcat tggctgcccc cacatctgga taagggccaa aataaagacc accgtccttt
    14701 ttgacctgac gagtaatgat aagccgtgga tagtgctcat tggtgatttt gataaaagga
    14761 taagacttgt catccttgag catgatattg tacttgggct tattttcctt gatcaggttg
    14821 atttccagca gaagcgcctc aatattagac tccgtaacaa taaattcaaa atccacaatt
    14881 tcagacacca aggcctctgt tttggtatca tgacttccac ggaaataaga cctcacgcga
    14941 ttacgcagat ttttagcctt tcctacatag ataatggtgc cgtttttatc cttgtaaatg
    15001 tagcaaccag ggctggtcgg caagagctct agttttggtt taatcaagtt gttcatagtt
    15061 ccattatagc aaaaaagtag ggaaagatag taccctactc attagtctca tatatttttc
    15121 ggaggtttgc aacatcctct tcctggatac cataaaagga acctgctggt tgcatgacag
    15181 acttctcatc tgtatggtcc aagccaatcg catgacctaa ctcatgttct gccgtatgga
    15241 caaggcgttc ataggaatag ccatagtatg gattggacaa ataataatga ttcaaccgca
    15301 ccgttacgga caagaattgc cctgttaaga gattagtttg actttccgcc tctcctgcca
    15361 caggagtgcc tccgtcgttc atctccgtag ccgtaatatc cgccttacta gactcagtca
    15421 cgagttcaaa gttaaaagca ccagtttgat tccagttctg gattgcttct aaataagcct
    15481 cttgaaagcg tgaatccatc tgcggatcca ggtaaatacg agcagaggcc tgtgcccacc
    15541 ttccttcaga atgctggtga ctatctgtct ggcttaactt aggcagttgc cctgttttct
    15601 cccattggtc aatactttgt tgaccaattt ttactgaccg ttctgcttgc tttagcgctc
    15661 cttgaaaatc cccgttcaga taccagagaa gtccgaaagc aagcacacat aagagcacaa
    15721 ctatccaaac cagacgccaa aacaaacgcc acacaaaaga aaagaaagcc cctatcaaac
    15781 gaaaaagcca gcgcatgtct ctccaccttt ctagcaaata agaattattt tactaaaaga
    15841 agctaaaaga aatctaaata ctgacttttt catcttaacg tcctactatt tttttgagta
    15901 actggatagc tttgtatttt aaaggcgatg gatggtaacg gaaagtaccc gctttgcgta
    15961 caatatagcc attaaaattc tgtttaaaac gcaaaacacc atcacttcca tcaaaaatcc
    16021 cttgaatgcc taggaaattg tatttaggta ttccacgttt tatgctttcc aacataacat
    16081 atttttgaag cagtgcaggg gcatagaact tattaaactc agtgtaggaa ccactaaaga
    16141 gataagtcgt ttcctgaggc atataaacaa ataaactccc agctaaaaca atatcttctt
    16201 ctccatattt ttcaatcaag tctcgcgctt ctgcttttcg aacttcaaac gtttcaaatt
    16261 gactagaata ttctctcagt tgattttgtt ttttctcaga atgaggattt ttactcaaat
    16321 caagtcgcaa cttgtccaag ttttcttcta gtttattttg ttcaccttgc aatttgctca
    16381 tatagtccga aaaatttaag cttgctatga gaaactccgc ttgttctcca aaagtatcat
    16441 aaaaatgctc ataatattct aaacttttat cactatattc tctacgttca gaggtttctt
    16501 ttgttatatt cttaaaaatc gatagttctt cacgttttaa ctttttcaac cgaatgccaa
    16561 aggtttcagc ctttttcacc aagggtttac cctttttgct aaaactttta agcaaactct
    16621 tttcagttaa ttcagttaaa tctttatagt ataaccaatc tggttctcca cctgggtaac
    16681 ctgttgttaa gccatcaaat tgataaccta aatcagtcaa atcttgaata atactttttt
    16741 tctcagcatc tattggatta ccttggctat caaaagtttg ataagtttca tagggtttta
    16801 caagcaactc taatacacca ttttgcttgg catattcttt taactctgca taaaaaactg
    16861 gaagagcatc ttgttgggta taaatcggcc ccgaattgag ttccatatgc agaccaccca
    16921 gcatgggcaa gctataaacc agagctgcaa cttgaatttc tccttcttgt ttcaaagcaa
    16981 gataaacaat tcgagcccct cttttttcta gcaaatcccc catctggaca gattgcataa
    17041 aggaacgaga agaaacctga tcagaataag tctgaaactc ttctttcgtg agtgttgtta
    17101 gtgccatata cttactttct atgttttttt cttaatgttt tacggaaatc aagagcaagt
    17161 cttaacagag gatagagagg atgagtgggc attgtaaatt cacccaagta ttcttcaatc
    17221 gttggattaa atttttcctt aaaatgataa agtccaccat tgagagagtt ttcaacacca
    17281 cctaaatttt gccagatcat acctcgctca aaggcatagc gagccgtttc ataccatgtt
    17341 aaaattggtg cattgtaacg tttaaaatca tcatccatac cagcatatat attgacagag
    17401 gtagtaccaa attccaaact caaagtagcc gctaaaggaa ctctcgcttg acctacatct
    17461 atatattcct gcaagaaggt caattcctct aacaaacgtt ctttttcctt cttctgcgct
    17521 tctacttttg aagttcgagt cgactcagta aacgtctctt ccaaggctct atttttcgct
    17581 aactgttctt ctaattcttg cgaacgttta gaaacatcca aggtggccaa ggtgatatag
    17641 gccttgtcct taaaattatc taacaatttt ttataatagg cttcattcct caaatgaatc
    17701 tcttttcgct tctcagtttt tttcatcaac tccgaaaatg aatctaatag ttccagtcca
    17761 ccatattgaa tctcaagccc tttgtttcgt gctgttcgaa tagtctgttt tgttgacttg
    17821 gaaagtttat cttcttcaaa attttccttg tatattttcg cctgaatacg aggttgaatg
    17881 gtgtctccca tttcctccgt ttttcctgac caccttactc ccatttgttg caaactatca
    17941 ataatagcca gattttcagg aaattctgtc ttttcctgat tgattaaact ttgagatagg
    18001 caaatacttg ggtcaaaagt cacaaaaacc gctctcttac tgcgagcata ggacttaata
    18061 gactgaatgg caaaattcaa gagttcttta tccccataat ccaatatagg tcctcttggg
    18121 atgtaaaaca ttttatagcc tagcggaaga gttctaatca aaatactagc tgtcgccagt
    18181 aatttttctt ccctgtaaac accaaacttc tcatgttgcc aattagactt aacttcctcc
    18241 caagcactac tttgtaatac attggctaat tcatgttctt tgacaaactg atcatattct
    18301 aatgtgggaa tgccaatttg ataacggtac atttcctact ctctttcctc cagtatttta
    18361 ttactattct actactttcg tttgaaaagt ctagtgaaaa catattttat tttagttcta
    18421 ctccccctat gctgaagttc aaactaagtc agtctctctt ctaatttgaa atcaattggt
    18481 agggttgtta aaaaaacttc caattgtttt tcccagtagt accactcgtg agttccagcg
    18541 ctatggctat aggtcacatc aaaacctagt tttttgagat ttttcactgc gagattattg
    18601 gcttcgtaca agaaatcctg ttcgccacac cacgcccaaa gtttggtctt tttatccgat
    18661 tttttagcca gactttcaag agaataggga ctagttgtcc agtctctaat ctctccaaaa
    18721 acacctctcc agtaggctgg acttcccaga ttttgacttt caggagaaaa gttttgaaag
    18781 ctgagggcac ctgaaaaact agctgcatga gaaaaacgat ttgtcgcaag agccagtttg
    18841 aaacagccgt agcctcccat agaaagacca gctataaagg tcttttcacg cttgctagtc
    18901 atattaggga agaagcgttt cagaacctgt ggcaattcct ctgctagagc cgtgtagtag
    18961 tcaaaaccat actgggtatc ggtgtaccaa ccattgctgg tattgggcat aacaacgatg
    19021 agattagttc ctcgaagcaa gcgttctaca ttggtccgct taagccaact attatgattt
    19081 ccagacatcc cgtgcaaaag gtacaagacg ggaatatctt cacactctgg ttcttccact
    19141 cgattggcat cagggtagag gacattcatc ccccactcca tatccaatac ttgtgagtaa
    19201 tactcgattt tcattactgc catgattttc tccttctatt tttctataag aaaaagccga
    19261 aactcgactt tctctctgtt tatttcaacg attattttgc ttccatgact actggtaaaa
    19321 tagctggacg acgcttggtt tggtcaaaga gatacttggt caaattatct cgaaccttcc
    19381 ctttaagatc tgcccagtca aagtcatctc cttgaagata atcttctacc gtttggttaa
    19441 tcaattctga actttcacgg agaatatcgc gactcttctt gagataaaca aatccacgcg
    19501 tgtgaacacg agctctagcc acaattttct tctcacgacg gttgactgta atagccacga
    19561 tgaaaattcc atcctctgac aagaccttac ggtcacgaag aacaacattt ccaacatcac
    19621 caatggcatt cccatcaatt aagatatctc ctgctgaaac cgatccagct ggaacaaagt
    19681 ctccattctc gtaagccatg gtcgtcccct ttttaggaat gaagatgcgt tctggcaaca
    19741 tcccaactgc catggcagcc ttagcgtgag catccaactc acgatactcc ccttggacag
    19801 ggaagaggta cttaggttgc aaaagattga tcatcagctg caaatcacgc acatttccgt
    19861 gccctgatac atgtaaactt tgggtaatca atttgacaac cccacctgcc tgataaatca
    19921 tattttctac acgcgcaaca aaggcttctt tagcaataga cggagccgta gcaatataga
    19981 ccaggtcccc atccttgatt tctacataac gatggcgacc aatcgacatc ttacgaagtc
    20041 cattgatagg ttcacccata cgacctgtct caagaataat caactcatgg tcttcaaagc
    20101 gagacatatc tttaggctta atcaagagaa tttcgttggc taaagacaac ttcttaagac
    20161 gaatcgctgt gcggacgata ttttcaatat caaatcctgt caagacgata cgtcgacctg
    20221 ttttatccgc agcgtcaaaa atctgctgaa tacgagaaag attactggaa acagctgcaa
    20281 cgatgatacg accttcccag tcagcaatag tttgggtaat ttcatcccta acttcacttt
    20341 cactagccac ctgaatattg ctgtctgcat tggccgaatc actgaggaga gccaggacgc
    20401 cgtcacgacc aatctctgcc aaacgagcaa aatcagttgc ataagattca ctagccgttt
    20461 ggtcaaattt gaagtcacct gtataaacga tgcttccttc cgatgtcttc aagacaattc
    20521 ccagactctc tggaacggag taagtcgtag ggaagaagga aaccactgtc ccaccaaaat
    20581 caatctccgt attctcatca atgacatgga aatcattaaa tttcttaacg gcatcatttc
    20641 ctttgacaaa gagctttgcc aactcaatgg tcaactcaga cccaaataca ggaactttag
    20701 cctctgccaa gagataaggt agagcaccaa tcgcatccgc atgcccgtgg gtcaagaaaa
    20761 ccccagcaat acggtcgcta ttttcaaaaa ggtaatccat gtttggaatc accacatcga
    20821 cccctaattg ttcattttca ggatatttta accctacatt caaaacaaaa atggactctc
    20881 caatttcagc aatgtacata ttttttccat tctcacgcac accaccaagt gttgttaaac
    20941 tgatattact catttttcct ccaaaatctt agtttatctt gattataggg caactctacc
    21001 ctcttattct aaaagttcta atactttcag ccgaatcttt tcctaccatt ataccatttt
    21061 tttgatgatt ttcaaaatga aggtctgttt tcaaaaaaga gttgatttcc caactctttc
    21121 ctaacttcta ctctttttcc atcaaaaaat cataaatttc ttgcaccata cccagcgcca
    21181 tcatttcttg gtctttaacg gtttgtttga gattttggta aatttgactt tctcctatct
    21241 cccgctttgg cgcctcttta ttgactgtca tcacaccatc ttttatcgtc acaaagccta
    21301 gttcttcaaa tacttgaatc atcttgacca gcaagatttg ttgaatatta agatatgcag
    21361 ccaaatcttt cagcttgtag cgaatatcaa actctgggaa ctggtaaata gtcttgtaca
    21421 atttggcaaa ctgatctcta gtcccataac ctgtcagata ataggccttg tcaatatcat
    21481 ttttgaaata gacagcagag aaatgctgtt cctgaaaaat ggtcttcagc tgagtaatat
    21541 cctctggaat gttttttacg acaatagctt cactagccgc aagatttggc agttctccag
    21601 gaaaatccaa gactggaaca ccttctggca agactgcatt ttttccacga atgttaaaaa
    21661 gttgaacacc ttccactcgc gcatccacca tcatcaactg gagggcagtt tggccattcc
    21721 attggttgac agacaattta accgctaact ctagattctt ggtttgagaa aactctgtcg
    21781 cccatctgcc ttgaccaaag gctaccactt caaaactcgc ctcacccttg gaaattttca
    21841 gctttagatg ggcattacct gcccccatag tacgagcact ttcgacctga aaattcttga
    21901 tataaaaaat aggtttctga ttatccattc caaaaggagc taaacgttca aaacttttga
    21961 ccgtttccaa gctaagtgcc tccaaatcca actcttcatc taggtttaac ttattcttgc
    22021 caccagcatc tgcacctttt tcacgaacat aatcttccaa aacctgagat aaatctgaga
    22081 gttgctcaac ttccagcgtc atacccgctg cacctgcatg acctccaaag gcgataaaga
    22141 ggtctcgatg gggatccaga gcttcaaaaa tatcgaccgc ttccacacta cgagcactgc
    22201 ccttggcacg accgtcttct atattaagaa caatgactgt ctgtcccaat tcttccaata
    22261 aacgaccagc cacgattcct agaaccccag gattccagcc ttccttggcc aagacctgaa
    22321 ccttcttctc aggatccacc atggtcttgg cttcttcata gatagactga acgatttcct
    22381 tgcgctcttc gtttttctgg tgaatcataa aggcaatctc atgcgcttcc tcatcatcaa
    22441 atccagtcaa caaatcaatg gcaggattgg gatcatccaa gcgacccaag gcattcaaac
    22501 gaggagcaat ctggaaacca accgtttctt ctgttacttc gttggcagca atcccagcca
    22561 tgtccagcat ttcttgcaga ccaatgcgct gggtatgacc caacatttcc agaccatatt
    22621 gaactaagat acgattttca tccgtcagac tcaccatatc tgcaatagtt ccaatagcga
    22681 ccaaatcaag caattccact tgcacttctt ctaacagggc acaagccaac ttgaaagcaa
    22741 ctccacaacc agccaaatat ttaaaaggat aatccgcatc tggatgttca ggatggacaa
    22801 tagcataagc atctggcagg gtttcaggca tggaatgatg gtctgtcaca atgacatcta
    22861 ctcccataga ctgagccaat gcaatagcct catgaccagc aaccccattg tccaccgtca
    22921 caatcaagga aattccttct tgctcgataa agtatttata aacactagca ttagggccat
    22981 agccatcggt aaaacgattt ggcaggtaaa ctcggcactc agcaccaagt tgttccaaac
    23041 tttccttcac aatagaagcc gaagtcatgc catccgcatc atagtctcca taaacgagaa
    23101 tattttcccc ttcttcaata gcctgacgaa tccgctccac tgccttgtcc atatcatgga
    23161 gcagataagc atcatgtaag tcctccaagg aaggttctaa aaacttcttc agactttctt
    23221 ggtcctgaat ccctctctca aacaataacc gagccacctc aggacccagt ccagccttct
    23281 tggctatctt tgtaaaatcc gcatcttcta cctgcagggc aaactgccat tcataagtag
    23341 gtgttatcaa aaagacatcc actctttcta agaattctat tgcttcatta taacatgatt
    23401 tagacgtttt ctctatccag attgcttttt tataacattt tatagtatat tgaaactaga
    23461 atagtacacc tctacttcta aaatattgtt agaaatcgat ttgactgtcc cgatcgattt
    23521 gtcctgttct tatttcacta tagtgaattt tttcagatat ggtttgacaa gaacattctt
    23581 ttattgtaga atcgtgttat aaaatctaac acaaaggaga tctctcatgg ctttagtaga
    23641 atttaaaaac gtcgaaaaat attacggaga ctaccacgca ctccgcaaca tcaatctccg
    23701 ttttgaaaaa ggacaagttg ttgtcctgct tggaccttct ggctctggga agtccactct
    23761 tatccgtacg atcaatggtt tagagactgt tgacaaagga agtctcctag tcaatgggca
    23821 ccaagttgct ggtgccagcc agaaagattt ggtacctctt cgcaaggaag tcggcatggt
    23881 ttttcaacat tttaaccttt atccacacaa aactgtgtta gaaaacgtaa cacttgcacc
    23941 cattaaagtt ctaggaattg ataaaaaaga agctgaaaaa accgcccaaa aatatctgga
    24001 atttgtaaat atgtgggaca agaaagattc ctatcccgcc atgctatctg gtggacaaaa
    24061 acagcggatc gccatcgctc gtggtcttgc tatgcatccg gaactcctcc tctttgatga
    24121 accaacatct gctcttgatc ctgagactat cggagatgtt ctagcagtta tgcagaaact
    24181 ggcgcatgat gggatgaaca tgatcatcgt tacccacgaa atgggctttg ctcgagaggt
    24241 tgcggaccgc attatcttta tggccgacgg agaagtttta gtagatacga cagatgtcga
    24301 taactttttt gacaatccaa gcgaacctcg tgcccaacaa ttcctcagca aaattatcaa
    24361 ccacgaaagt gacaaagtca aataaggagg cgcctatgaa aaaaaaattc tttttatcag
    24421 cattattgat tagccttttc ggccttgctg ctgccaaacc agtccaggct gatactagta
    24481 tcgcagacat tcaaaaaaga ggcgaactgg ttgtcggtgt caaacaagac gttcccaatt
    24541 ttggttacaa agatcccaag accggtactt attctggtat cgaaaccgac ttggccaaga
    24601 tggtagctga tgaactcaag gtcaagattc gctatgtgcc ggttacagca caaacccgcg
    24661 gcccccttct agacaatgaa caggtcgata tggatatcgc gacctttacc atcacggacg
    24721 aacgcaaaaa actctacaac tttaccagtc cctactacac agacgcttct ggatttttgg
    24781 tcaataaatc tgccaaaatc aaaaagattg aggacctaaa cggcaaaacc atcggagtcg
    24841 cccaaggttc tatcacccaa cgcctaatta ctgaactggg taaaaagaaa ggtctgaagt
    24901 ttaaattcgt cgaacttggt tcctatccag aattgattac ttccctgcac gctcatcgta
    24961 tcgatgcctt ttccgttgac cgctctattc tatctggcta cactaataaa cggacagcac
    25021 tactagatga tagtttcaag ccatctgact acggtattgt taccaagaaa tcaaatacag
    25081 agctcaacga ctatcttgat aacttggtta ctaaatggag caaggatggt agtttgcaga
    25141 aactttatga ccgttacaag ctcaaaccat ctagtcatac cgcagattaa ggaggatacc
    25201 ctatgacaga tttatcatct tggacagcct attttcagga ttttggacaa tttttcaatg
    25261 gtttcctctt tactcttgcc ctagcgattg gatcctttat cctcgccatg gtcttaggaa
    25321 tcttctttgg tgccatgtca accagtaaac gtccaatttt acgcatttta gctcgcatct
    25381 ttgttgaatt ttaccaaaat actcccctct tggtgcagtt tgttattgtt ttttatggcc
    25441 tacctcttat cagtgaccat atcatcatga ttccaattta ttggacagcc gttctctgcg
    25501 tgggactcta tcacggcgct tatatcgctg aggttattcg ttcagggatt cagtctattc
    25561 ctagtggtca gatggaggcc gccttgtcgc aaggttttac ctatatcagt gccatgcgct
    25621 tgattatctt gcctcaggcc ttccgcatca ttctccctcc attgaccaac caaattgtta
    25681 acctcatcaa gaacacctct actgtagcta tcatctctgg agtagacttg atgtttgtga
    25741 ctaagtcttg gtcggctctc aacggaaact atatcccagc ctttttaggt gctgctcttc
    25801 tctactttgc cctatgcttc cctgttgccc agtttggtcg caagatggag caagccaaca
    25861 aaaaagccta ttcactttag gaggttacta tggaatctat tttagaagtt ttaaccccag
    25921 ataacctagt ctttatcttt aaaggatttg gcttgaccct ctatatttct ctgattgcca
    25981 tcatcctctc tactatcatc ggtacggtgc tagctgtcat gagaaatggc aaaaatcctg
    26041 tcttgcgaat catctccagt atttatatcg agtttgtgcg caacgttccc aaccttctct
    26101 ggatttttac tatctttttg gtgttcaaaa tgaaatccac accagcaggt attacagcct
    26161 ttactctctt tacatcagca gccttggttg agattattcg aggcggtctc aatgccgtag
    26221 acaagggaca atacgaagca ggaatgtcac aaggcttcac ctcagcccaa atcctctact
    26281 acatcattct cccacaagcc atccgcaaaa tgctaccagc catcatttct cagtttgtta
    26341 ccgtgattaa ggataccagt ctcctctact ctgttatcgc cctacaagaa ctctttggag
    26401 ccagccaaat tctcatgggc cgttattttg aaccagagca ggtcttcagt ctttacatcc
    26461 tgattgccct catctacttc agctttaacc tagcaatttc tagcctgtct catatgctag
    26521 ccaaacgttg gcaacaagct gcagaataat actcttcgaa aatctcttca aaccacgtca
    26581 gctctatctg caacctcaaa acagtgtttt gagcaacttg cggctagctt cctagtttgc
    26641 tctttgattt tcattgagta taaacagcca ctctccagtt caattggaga gttttttgat
    26701 gagagtagat atttatagac ctcaatttga caccatacat tttctatgat aaaatgtaac
    26761 aaattcattt acaacaaatc gaaatctaaa tgaaatggaa ttttctatga aatcagtcaa
    26821 aggactactc tttatcatag ctagttttat cttgactctt ttgacttgga tgaacacttc
    26881 tccccaattc atgattccag gactagcttt aacaagccta tctctgactt ttatcctagc
    26941 cactcgtctc ccactactag aaagctggtt tcacggtttg gagaaggtct acaccgtcca
    27001 caaattcaca gcctttctct ccatcatcct actaatcttt cataacttta gtatgggcgg
    27061 tttgtggggc tctcgcttag ctgctcagtt tggcaatctt gccatctata tctttgccag
    27121 catcatcctt gtcgcctatt taggcaaata catccaatac gaagcttggc gatggattca
    27181 ccgcctggtt tacctagcct atattttagg actctttcac atctacatga taatgggcaa
    27241 tcgtctcctt acatttaatc ttctaagttt tcttgttggt agctatgccc ttttaggctt
    27301 actagctggt ttttatatca tttttctata tcaaaagatt tccttcccct atctaggaaa
    27361 aattacccat ctcaaacgct taaatcacga tactagagaa attcaaatcc atcttagcag
    27421 acctttcaac tatcaatcag gacaatttgc ctttctaaag attttccaag aaggctttga
    27481 aagtgctccg catccctttt ctatctcagg aggtcatggt caaactcttt actttactat
    27541 taaaaattca ggcgaccata ccaagaatat ctatgataat cttcaagccg gcagcaaagt
    27601 aaccctagac agagcttacg gacacatgat catagaagaa ggacgagaaa atcaggtttg
    27661 gattgctgga ggtattggga tcaccccctt catctcttac atccgtgaac atcctatttt
    27721 agataaacag gttcacttct actatagctt ccgtggagat gaaaatgcag tctacctaga
    27781 tttactccgt aactatgctc agaaaaatcc taattttgaa ctccatctaa tcgacagtac
    27841 gaaagacggc tatcttaatt ttgaacaaaa agaagtgccc gaacatgcaa ccgtctatat
    27901 gtgtggtcct atttctatga tgaaggcact tgccaaacag attaagaaac aaaatccaaa
    27961 aacagagctt atttacgaag gattcaagtt caaataagta atcatactct cctgggattt
    28021 cccaggagag ttttttatag ccaaatgaaa taagacagga acgatggaat tttggcattc
    28081 aaatcaattg ataagaatgt tttatagtgg agtgaaatag gatacgaaca aattgattag
    28141 gaaaatcaaa tgaatttata gaaatctttt agcagttatg ttgtcctatt ctagtttcaa
    28201 aacgctatag aagcagcatt gtgctagtct agattcagtt tactatacta aaacgagtag
    28261 cttgaaatca aaaaacccac cctcacaggc aggttttatc tgtattattc agctagatta
    28321 tgctttacct tctgaaccga atacgtcgat acgttcttca accgatgctt ggatagcttt
    28381 tacaccgtca gccaagaatt tacgtgggtc gaagagtttt ttcttgtcgt attctgcttc
    28441 gtttgcttcg tagtcacgag caaatttacg agttgcgtta gcgaatgcga tttggcattc
    28501 tgtgttaacg ttaactttgg caacaccaag tttgatagct gcttggattt gctcatcagg
    28561 aatacctgat ccaccgtgca atacgattgg gaatcctgga agagcttctg tcaatttttg
    28621 caagtggtca aggtcaagac cttcccagtt tactgggtaa ggaccgtgga tgttaccgat
    28681 accagctgcc aagaagtcga taccagtttc aaccattgct ttagcgtctt cgattggagc
    28741 caattcacct ttaccgatga ttccgtcttc ttcaccaccg atagtaccaa cttcagcttc
    28801 tactgagata cctttagcgt gtgctttttc aacaacttct ttagccaatt taaggttttc
    28861 ttcaactgga aggtgtgaac cgtcaaacat gattgaagta taaccaactt cgatacactc
    28921 aagtgcatct tcgtagtgac cgtggtcaag gtggatagct actggtacag tgatacccat
    28981 tgattcaaca aggttagcga tcaagttgcg agcaactttg taaccaccca tgtatttagc
    29041 agcacccatt gaagtttgga tcaaaactgg agctttttta gcttctgctg cgcgcaagat
    29101 agcttgagtc cactcaaggt tgtttgtgtt aaatccacca actgcataac cgttgtcacg
    29161 ggctgcttgg acaaattttt ctgctgaaac gattgccatt ttatcaggcc tcctgtatat
    29221 ttttatgggt catcccattt acattgttca ttttatcact ttttgccaaa aaaatctagt
    29281 ttttcccgca gtttcgattg attttcttct aactccatct atgtaaaccc tttctctccc
    29341 tagtcttgga cgacttttgg aaaatctata aagaaggtta aacgattctc ctccatctcg
    29401 aaacgataag ctaatttttc atgttctaat agactcttaa ccacaaagag ccccatacca
    29461 gaccccttga ccttgcgact ggcattgtca gaaaaagact gggctagttt ttcttgttcc
    29521 tctgagctac agctattttc gataaaaagt tctccttctc tttctccaat tcgaactaag
    29581 ccacctggaa cagagtgctt aatggcattg ctgatgagat tagaaagaat caacttcata
    29641 actgatgggt ttagataagc ctgctgatgg gtcaaactat tgtctatctg gagctctctt
    29701 tccttggcta gcaaggcata atctttgacc agattttgcg tcatctggag gaggtcaatt
    29761 gtttccctat catctcgcaa ttcctgcaca gaagagaggg aaagtatctg cagaacatgg
    29821 tgattgagtt catccacaat ccccaaggca actcccagat actggtctct atccttataa
    29881 cgaccgatat tctctctcat attttcgatt aggattttca aactagccag cggtgttttc
    29941 aattcatgag aagctcctcg taggaattcg accttcatct tctccagctg gagaatggct
    30001 tcattctttt catgcaagtc cgcaataaca gtcaagagat gctggtagag gctattgatt
    30061 tgttccttga gattacctat ctcatcctta gaatccacgc gcaatcgcac ttgggcatcc
    30121 aggtacatca tccgacgagt cacccgcttg atttccaaaa tcggtgcaac aatagtccga
    30181 gcgtagatgt aggccaccaa gagggaaatc agaaaggagg ccagcaaggt atagggaaga
    30241 aactggagac tgatttgctc cgcttccttt tgtaaatcca tggaagctag aaactggaga
    30301 atcatagtac caccgtcttg cgttttcacc tcgcgctcct caataaagag agaggttgtc
    30361 tggcggtctg tgtccagagg aagactgtcc ttgacttcta acttgtcctc ggtcatctca
    30421 cctttgacgg tccccttgat atcactagtc tgggaataca agtctaacac ttgctcgata
    30481 ctctgcctat ctttcccttc tagggactgg gcaatggctg ttgccttttg accaatggtt
    30541 tcctgacgat gactcagata agtcgaagga aaaagaaaat aaatagctaa atgaaggcag
    30601 ataaccagaa cactaaatat cgagaaggta tagataaata tctttgcaaa taaacctgtt
    30661 cgtttcattt tcgctccaat ttataaccaa cattgcgcac agtgaggata caatccaagt
    30721 ctagcttttt ccgcaattcc ttgatataaa catcaataac acggtcaaag ggaacctcat
    30781 ctgtcgcttt ccagacggca tcgataatct gagatcgagt caaggcccgg ccttcatttt
    30841 tcactagata gtccagaatt tccaactctt tggcattgat aggcacttct tgacctgcga
    30901 tgcttgcact gtagctttca aagtccacct tggtatcctt gtaagaaaag attcgtcctg
    30961 tatcgtagta gcgcttgaaa atcgcgtcca ccctcacttt taaaagggag agggagaaag
    31021 gtttttccag atagccatct gccaaagagg caaaggcact catcttgtat tcctcatcct
    31081 gaaaagctgt caacatcaag acaggaacct gactggtttt acgaatctca gctaggactt
    31141 ctaagccgtt gagcttgggc atctggatat ccagtaaaac cagggccacc tcatagctag
    31201 aaaattgctc cagagcttcc tgaccgtccg ctgcctcaat agtttcatag ccacaatccg
    31261 tcaaataatc actgaccccc tcacggatca tctcttcatc ttctacaatt aaaattttca
    31321 tactttaact gctctctatt ttttattttt cttagaataa atacctactc tattttctat
    31381 tatagtctct tgctggcctt ttgtctgtaa gtaactgacc actagataaa acgttgtgaa
    31441 attcctttct cataaattcc ataactttag tatattatat ttaagcacta aagtacaaag
    31501 aaagcaactg aaagcaatga ttttcaccac tgctttcaga tttattttga attgttaaat
    31561 agccattcct atccactatt cttgaataga aacacaagat gcaatcttta ttccagactc
    31621 attttttcaa atttattcac catccagcaa gagttctttt ggttgttttc taaggagatt
    31681 gcttgaagca agcgccataa cgagaaccac tagaaccaag gcaaggacaa aaatgatgat
    31741 aaagtctgat gtctgaatgg aaatgtctag gctcgacaag gtcttgctaa agccatctac
    31801 ttctgcacca ccaccaaggt tagaggcttg agccgcctta ctagcctgtt tggcaacacc
    31861 tgaagtcaca ttggcaagga cagtgtttcc aattgcacgg gcagtgtaat tagctaggaa
    31921 gtaagcagaa actagagcag ggatagcaat caagatagat tcggtgatga attgacccaa
    31981 gatacttgcc tgcttgaggc cgatagagag gagaattccc acttccttgc gacgggcgtt
    32041 gatccaaagg ctgagcaaga gggcaaggag gagaactgag aagctcaagc taccccagaa
    32101 gaggaggttg gccatcttgt acataccaga gatagattgc tcaagagctg ggtagttaga
    32161 ggagctcttg acgagtgtgt agctcttcca gttgatacca ctgatgccat tcaactcttt
    32221 cataacatca tccaagttct tgtctgctgt tacaaagaag gttgcgtccc cataaatggc
    32281 tgtgtcttct gtgtatccat aaagttttgc agcagtgtga atgtctgtaa tagctgtgtt
    32341 ttcgtaaagt tcttgtgagt aggttactgc tgacttatta tgaccatcaa agagtccctt
    32401 gattgtcact tcaactgttt ccttggctcc tttttcatta tctgcatcgt agatattaga
    32461 gtccagttta accttgtccc ctactttcca gccgtgtttg gctgccaagt ccttgtgcaa
    32521 gaggatttta tccttgtcgt cgttggttaa gtgctctcct tcgactagtt tataagaacc
    32581 agagacaaac ttgtcttctt tagaggagtc attgacacct gtaatcatca agctacttcc
    32641 aaaacgtttg gcacgatcag cagtgagatt cttcttggtt tctggcgttt caatcaggtc
    32701 atatccagtc aaatctccga tagcgttgat acgtttgaca taagactcga tggccttgtt
    32761 ttcggtgatt tttttgatgt cttcaccctt gatattccca gcaccacgag gcgttccttg
    32821 gttgacgcga cgattgattt gcatggagaa gctattggtg atatttttaa aggtctcctg
    32881 agaagccttg gcagtagctc ccttgattga caagccgacc aaactcaagc tcgccatgag
    32941 gagaataatc aggaagatga caatcgattt gaaaaacttc cttgtaacat aggcaaatgc
    33001 gttgtgtaac atagattccc tttctagatt ttgttttaat cattctatca aaataagctc
    33061 aaattattta ctagtattgc gcgtttcagt cagtttctta tcctttaatt caagtgtaat
    33121 atctgacgct tgtgccactt ctttactgtg agttacgaca atcacacatt tacctgtttt
    33181 ctgggcaagt gatttgagta gttcgacaat atctccagca gttttaggat ccagatttcc
    33241 tgttggctca tcagctagaa taactggagc ttctgagacc aaactgcgag caatggcaac
    33301 acgttgctgt tgaccacctg ataactggag aacattccgc ttgatctggc tttcatccaa
    33361 accaagctca agaagtgtat tcttgcttgc ctttttgttg accaatcgga tattttccag
    33421 cggagaaaga taatctatca agttataatt ttgaaagacc agggaaatat ggtgcatgcg
    33481 atggtaagaa tagcccttct tacgaatatc ctctccttga aaaaggatag aaccttcaac
    33541 aggactatct agaccagcaa gtagggacaa gagtgtggat tttcctgctc ctgactcccc
    33601 aataatactg taaaattttc caggttcaaa attataatcg atctgatata ggactgcttc
    33661 agcagtattc ttataacggt aggtaacatc ttgtaattgt aataaagtca tgatttctcc
    33721 ttcttaacta atagatgata aaatttcttt cggtgatttt ctaaataaga ataggaaaca
    33781 aagggctaca gataagcaac taagcagaac tagaaaaaca taggattctg caaaagataa
    33841 gatgctagtt gataaactgc ttgctttggc tagtgtatct tgtaagcttg cctgatctcc
    33901 acttgctagt agagtttgga gtaggtaagt tgtgattccg tttcctgcaa caaatgctgg
    33961 aagcaaagct ccaagagata ccaaaactac ctctaaacag aattgtagga agatcgagct
    34021 cttgcctttt ccaagtgcaa gtaaaatccc cacttcatag acccgttctc tcaaccagag
    34081 agacaaaacc agaattaagg ctccagctcc tgctatcaac atcccataaa ggaagatggt
    34141 caggaaggtt tggaaagttg caactgagtc tttgatttgt tcaaaagcct tgttttcctt
    34201 ttcgacttgg tagccttgat tttccaaggc caagttttct acctgcttca tgagtccgtc
    34261 catttcctta ggattttcta catagaagcg tgctgcactg acttgagctt cactattgcc
    34321 caaaagggtt tggctacttt catagtctgt aaagacttga ttttcactga agtcagaaga
    34381 caagcctgtg aatttctctt gttttttacc agaaaagatg ccaataatct caaactctac
    34441 tgtttgtcct tttccagatt cagactgacc agcatccaag ccaatcttgt catgaagtga
    34501 aagaccgttc ttcttagcca attcttcgtg gataaggatt ttcttggaat cccctttttg
    34561 aaggtgtcgc ccttctttta gattgaaagc cgaactggta aaggttacat ccttggatga
    34621 atcctcaaga gccgttaagc taaccaagtt attgtctgca gctgataaat catcacgctc
    34681 cacgctctgc tctccagtca ctgcttcctt gtcttttagt tttgcgaccg tctcaagttc
    34741 aggagagaca ttttccagcc ccttaatctt gcttacagat gctaggtctg acaacttgaa
    34801 tgtctgacca ttctctatct tcttaataga aaaagatgta ttgagtgatt tataaagatt
    34861 gctttctact gttttgttgg acttcatcag agtcaaacag gctgaaattc cggccaataa
    34921 gaccaataaa atcagaaata aaataaaact tctcagtcgc tttctgctga cataagccca
    34981 agatctttgg attggattca tttgtcacct ccatatttgt aagactatta taaaacccaa
    35041 atatgaaatg tttatgaaat acgaaaaaaa aatatcgagt aggggataat ctctagcccc
    35101 tctcacacca ccgtacgtgc cgttcggcat acggc
//
LOCUS       DBJKQU010000017        34698 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.017, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000017 DBJKQU010000000
VERSION     DBJKQU010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34698
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.017"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            66..1958
                     /gene="pepO"
                     /locus_tag="ACSUUC_000937"
     CDS             66..1958
                     /gene="pepO"
                     /locus_tag="ACSUUC_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HHQ8054170.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2080..2709)
                     /locus_tag="ACSUUC_000938"
     CDS             complement(2080..2709)
                     /locus_tag="ACSUUC_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHQ8054171.1"
                     /translation="MKIYKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            3703..5925
                     /locus_tag="ACSUUC_000939"
     CDS             3703..5925
                     /locus_tag="ACSUUC_000939"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0008893 - guanosine-3',5'-bis(diphosphate)
                     3'-diphosphatase activity [Evidence IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT family protein"
                     /protein_id="HHQ8054172.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            5955..6398
                     /gene="dtd"
                     /locus_tag="ACSUUC_000940"
     CDS             5955..6398
                     /gene="dtd"
                     /locus_tag="ACSUUC_000940"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - peptidyl-tRNA hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HHQ8054173.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6665..6850)
                     /locus_tag="ACSUUC_000941"
     CDS             complement(6665..6850)
                     /locus_tag="ACSUUC_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054174.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(6869..7282)
                     /locus_tag="ACSUUC_000942"
     CDS             complement(6869..7282)
                     /locus_tag="ACSUUC_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054175.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(7413..8120)
                     /locus_tag="ACSUUC_000943"
     CDS             complement(7413..8120)
                     /locus_tag="ACSUUC_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter family
                     protein"
                     /protein_id="HHQ8054176.1"
                     /translation="MKKSLKIFATSKWFDLFGVALVVGIAIASGYLNSRLDKFVDWGL
                     WTALVPFGLISVTNVGISMLSTRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIIT
                     YPVTFLIYTFAIKKWKASQEGRPNQISQKQVKLAVIIISIIAFLFAFVTNYIGYEGKM
                     NLLAYVTTIAFALSLIANALNALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFY
                     ILNAIGALFVWNDEEVR"
     gene            complement(8239..8889)
                     /locus_tag="ACSUUC_000944"
     CDS             complement(8239..8889)
                     /locus_tag="ACSUUC_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HHQ8054177.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMVIAKQLYVEKIN"
     gene            9001..9843
                     /locus_tag="ACSUUC_000945"
     CDS             9001..9843
                     /locus_tag="ACSUUC_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HHQ8054178.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQLHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            9919..10356
                     /locus_tag="ACSUUC_000946"
     CDS             9919..10356
                     /locus_tag="ACSUUC_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HHQ8054179.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            10425..10727
                     /locus_tag="ACSUUC_000947"
     CDS             10425..10727
                     /locus_tag="ACSUUC_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054180.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSFISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(10818..11891)
                     /locus_tag="ACSUUC_000948"
     CDS             complement(10818..11891)
                     /locus_tag="ACSUUC_000948"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HHQ8054181.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPSQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPK
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            12047..12724
                     /locus_tag="ACSUUC_000949"
     CDS             12047..12724
                     /locus_tag="ACSUUC_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHQ8054182.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            12717..13691
                     /locus_tag="ACSUUC_000950"
     CDS             12717..13691
                     /locus_tag="ACSUUC_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HHQ8054183.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(13740..15683)
                     /gene="thrS"
                     /locus_tag="ACSUUC_000951"
     CDS             complement(13740..15683)
                     /gene="thrS"
                     /locus_tag="ACSUUC_000951"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HHQ8054184.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(15741..16064)
                     /locus_tag="ACSUUC_000952"
                     /pseudo
     CDS             complement(15741..16064)
                     /locus_tag="ACSUUC_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(16321..16684)
                     /locus_tag="ACSUUC_000953"
                     /pseudo
     CDS             complement(16321..16684)
                     /locus_tag="ACSUUC_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397621.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16921..17550
                     /locus_tag="ACSUUC_000954"
     CDS             16921..17550
                     /locus_tag="ACSUUC_000954"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HHQ8054185.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTPDFPEEFKPLAKAQADEFDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            17691..17960
                     /gene="rpsO"
                     /locus_tag="ACSUUC_000955"
     CDS             17691..17960
                     /gene="rpsO"
                     /locus_tag="ACSUUC_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HHQ8054186.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            18775..19389
                     /locus_tag="ACSUUC_000956"
     CDS             18775..19389
                     /locus_tag="ACSUUC_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HHQ8054187.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(19682..20431)
                     /locus_tag="ACSUUC_000957"
     CDS             complement(19682..20431)
                     /locus_tag="ACSUUC_000957"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HHQ8054188.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            20564..22900
                     /locus_tag="ACSUUC_000958"
     CDS             20564..22900
                     /locus_tag="ACSUUC_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HHQ8054189.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            23002..23679
                     /locus_tag="ACSUUC_000959"
     CDS             23002..23679
                     /locus_tag="ACSUUC_000959"
                     /EC_number="2.1.1.217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0160105 - tRNA
                     (adenine(22)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase"
                     /protein_id="HHQ8054190.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            23666..24463
                     /locus_tag="ACSUUC_000960"
     CDS             23666..24463
                     /locus_tag="ACSUUC_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HHQ8054191.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            24480..25583
                     /locus_tag="ACSUUC_000961"
     CDS             24480..25583
                     /locus_tag="ACSUUC_000961"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HHQ8054192.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            25839..26858
                     /gene="galE"
                     /locus_tag="ACSUUC_000962"
     CDS             25839..26858
                     /gene="galE"
                     /locus_tag="ACSUUC_000962"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HHQ8054193.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKVMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            26860..27825
                     /locus_tag="ACSUUC_000963"
     CDS             26860..27825
                     /locus_tag="ACSUUC_000963"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHQ8054194.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAAHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(27876..28082)
                     /locus_tag="ACSUUC_000964"
     CDS             complement(27876..28082)
                     /locus_tag="ACSUUC_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HHQ8054195.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            28134..28610
                     /locus_tag="ACSUUC_000965"
     CDS             28134..28610
                     /locus_tag="ACSUUC_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HHQ8054196.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSELESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            28619..29290
                     /gene="cmk"
                     /locus_tag="ACSUUC_000966"
     CDS             28619..29290
                     /gene="cmk"
                     /locus_tag="ACSUUC_000966"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HHQ8054197.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            29421..29759
                     /locus_tag="ACSUUC_000967"
     CDS             29421..29759
                     /locus_tag="ACSUUC_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HHQ8054198.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            29762..30391
                     /locus_tag="ACSUUC_000968"
     CDS             29762..30391
                     /locus_tag="ACSUUC_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HHQ8054199.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            30631..31782
                     /locus_tag="ACSUUC_000969"
     CDS             30631..31782
                     /locus_tag="ACSUUC_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHQ8054200.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            32095..32844
                     /gene="truA"
                     /locus_tag="ACSUUC_000970"
     CDS             32095..32844
                     /gene="truA"
                     /locus_tag="ACSUUC_000970"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HHQ8054201.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFILDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRKLAGPTAAPNGLYLKEIRYEE"
     gene            32834..33607
                     /locus_tag="ACSUUC_000971"
     CDS             32834..33607
                     /locus_tag="ACSUUC_000971"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HHQ8054202.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            33585..34046
                     /locus_tag="ACSUUC_000972"
     CDS             33585..34046
                     /locus_tag="ACSUUC_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHQ8054203.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            34271..34698
                     /locus_tag="ACSUUC_000973"
                     /pseudo
     CDS             34271..34698
                     /locus_tag="ACSUUC_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        10043 a         6512 c         7942 g        10201 t
ORIGIN      
        1 attaattgca ttccctagtg atttttgtta agataaatgc aaatacaaat gaaagcgaga
       61 acaagatgac acgttatcaa gatgattttt atgatgctat caatggagaa tggcaacaga
      121 cagctgaaat cccagcagat aagtctcaaa ctggaggttt tgttgattta gaccaggaaa
      181 ttgaagacct gatgctggcg acaacagaca agtggttagc aggtgaagag gtgcctgagg
      241 atgctatctt ggaaaacttt gtcaaatacc accgcctagt tcgtgatttt gacaagagag
      301 aagctgacgg tatcacacct gtcttaccac tccttaaaga attccaagaa ttggaaactt
      361 ttgcggattt tacagctaaa ctagcagagt ttgagcttgc aggaaaacca aacttccttc
      421 cttttggtgt atcgccagac tttatggatg ctagaatcaa tgttctatgg gctagcgctc
      481 caagcacaat cttgccagat acgacctact atgcagaaga acatcctcag cgcgaagaac
      541 tcttgactct ttggaaagaa agcagcgcaa atctcctcaa ggcttatgat ttctctgatg
      601 aagaaattga agacttgcta gaaaaaagac ttgaattgga ccgccgagtt gcggcagtgg
      661 tgctctctaa tgaagaaagt tcagaatatg ctaaactcta tcatccatat tcttacgaag
      721 atttcaagaa attcgcgcct gccctacctt tggatgactt cttcaaagca gttattgggc
      781 aattaccaga caaggttatt gtagacgagg aacgtttctg gcaagcagca gagcaattct
      841 acagtgagga agcctggtct ctccttaaag caaccttgat tttgagtgtt gtcaatcttt
      901 caaccagcta tttaacagag gatatccgtg ttttgtctgg tgcctacagc cgtgcccttt
      961 ctggagttcc agaggcaaaa gataaggtca aagcagctta tcatctagca caagaacctt
     1021 tcaagcaagc cctgggtctt tggtacgccc gtgagaagtt ctctccagaa gccaaggcgg
     1081 atgtggagaa aaaagtggca accatgattg atgtttataa ggagcgtctg cttaagaatg
     1141 actggctcac tccagaaacc tgtaaacagg ctatcgtgaa gctcaatgtg atcaaacctt
     1201 atattggcta tccagaagaa ttgcctgcac gttacaagga taaggtagtg aatgaaactg
     1261 ccagtctttt tgagaatgct ctagcctttg cgcgtgtgga aatcaagcac agttggagta
     1321 agtggaacca gcctgtagat tataaggaat ggggcatgcc tgctcatatg gtcaatgcct
     1381 actacaatcc tcagaagaac ctgattgtct ttccagcggc cattttacag gcgcctttct
     1441 atgacttgca tcagtcatct tctgctaact acggtggtat tggggcagtg attgcccatg
     1501 aaatttccca cgcctttgat actaacgggg cttcctttga cgaaaatggt agcctcaagg
     1561 attggtggac agagagcgac tatgctgcct tcaaggagaa aacacaaaaa gtcattgacc
     1621 aatttgatgg acaggattct tatggagcaa ccattaacgg taaattgact gtatcagaaa
     1681 acgtggctga cttgggagga atcgcagcag cgcttgaagc agctaagaga gaagcagact
     1741 tctcagcaga agagttcttc tacaacttcg gtcgcatctg gcgcatgaaa ggtcgaccag
     1801 aatttatgaa acttttggct agcgtcgatg tgcacgcacc agccaaactc cgtgtcaatg
     1861 tgcaagtacc aaacttcgac gatttcttta caacctatga tgtcaaagaa ggagacggaa
     1921 tgtggcgttc accagaggag cgcgtgatta tttggtaata caaaaaatct agtcatcaga
     1981 aaaaggcatc caatcacgtg tgaaaacctt gataggatgc cttttgtaat agaaagattt
     2041 gctggatagt ttacttaaat ttcgattgtc atcatcttgc taaaaaaagg gattgaaggc
     2101 cttttcgtga gcgatagtag tagctggacc atgtcctgga tagacatcgt agtttggtag
     2161 ggtgaagagt tgggtctgga tactatgaag gagttgctcc atgctaccag tcggaaggtc
     2221 ggtccgtccg atagtttcgc ggaatagagc atctcccgtc aagactaggt gagcatcagg
     2281 aaagactagg gaaacaccac cgatagagtg ccctggggtc ggtagaacct taaaacgaaa
     2341 ttcctctagt tggtattctt cgtgaaagac aaaggtgtgt tctgcaggtt ttgtgaccac
     2401 atctgccata tcatcgtggc gagggagacc ggagagatta tcgacaggag tgtagagcca
     2461 gctggcttcg ctctctgcga tatagacagg aggattgcca aacgtctcgc gaaccaagtc
     2521 cagactcatg atatggtcat aatgggcgtg ggtcaagaga atagcacaga tcggtttgtt
     2581 gatcttctcg attgtctgac gaatggcttc ccaatgacta ccaggatcga cgacgatgag
     2641 gtgcttttcg ccttctagat aataggtatt ttcataggca acaggattca cggttttata
     2701 gattttcata ctagctccaa tctcaaagaa tatactaata ctcttcgaaa atctcttcaa
     2761 accgcgtcaa ctttatctgc aacctcaaag cagtgctttg aacagcctgc ggctagcttt
     2821 ctagtttgct ctttgatttt cattgagtat aaattaagta tagcacagtt agggagaata
     2881 ggtaaggatt taaaatgaac ttaaaaacca gcatgactag atgaagacag gctggttatc
     2941 aatttatcaa tattggaaag gtgtcaattg cccttcatag gttgcataaa ctccgtcatt
     3001 agcttgtttg atagacgtga tgtttagagt gctaccgtag ttggcttctc atttgtcgct
     3061 atattcacta taagttatcc tactgggcag gttctggtcg ttagcatagt attgaacgag
     3121 ttttttatag ctttgctggc tgaataggaa caggcagcaa actcctaaca ttaggagagc
     3181 aaagatagaa atagcagttt ttttcatagg tattctcctt ataaactaaa ggatagaaga
     3241 aagtatcttg aggattttta tactcttcaa aaatctcttc aaaccgcgtc aacgtcgcct
     3301 tgccgtatat atgtgactga ctttgtcagt cttatctaca acctcaaagc agtgctttga
     3361 gcaacctgcg gctagtttcc tagtttgctc tttgattttc attgagtatt aattccaaaa
     3421 tccagtcaag gtaccagtgt atgtgatacg agttccaccg tttatctttc gtatcttcaa
     3481 tggaattggg gaaatcagaa agtctttggg ttacaatatg gtttccgttc ttctatctct
     3541 ccttctatca cctaagttta aaatctaact tcgtagtata ttatgggcca ataattcaga
     3601 attatcaagc aattttgaat tatttttttc ttattctgtt ccaatctagt tttcatattc
     3661 ttaaaaaagt gataaaatgg taggaagaat tggagagtag agatgccgaa agaagtgaat
     3721 ttaacaggcg aagaagttgt cgctttaacc aaagaatatt taacggaaga ggatgttcat
     3781 tttgtccata aggccttggt ctatgctgtt gaatgccaca gtggtcaata tcgcaaatca
     3841 ggcgagcctt atatcattca ccctatccaa gtggcaggta ttttagctaa gctaaagctg
     3901 gatgctgtaa cagtagcttg tggattcttg catgatgtgg tggaagatac agatgcgacc
     3961 ttggacgatt tggaaagaga gtttggtcct gatgtgcggg tgattgttga cggagttacc
     4021 aagcttggca aggtcgagta caaatcgatc gaggagcaat tagcggaaaa tcatcgcaag
     4081 atgctcatgg ccatgtctga ggacatccgc gttattttgg tcaaactgtc tgaccgcttg
     4141 cacaatatgc ggaccctgaa acatcttcga aaagacaagc aggagcgtat ttccaaagaa
     4201 accatggaaa tctatgcccc acttgcccat cgtttgggga tttccagtgt caaatgggaa
     4261 ttagaagact tgtctttccg ttatctcaat ccaacggagt tttacaagat tacccatatg
     4321 atgaaggaaa agcgcaggga gcgtgaggcc ttggtggatg aggtagtcac aaaattagag
     4381 gagtatacga cagaacgtca cttgaaaggg aagatttatg gtcgtcccaa gcatatttac
     4441 tcaattttcc gcaaaatgca ggacaagaga aaacggtttg aggaaatcta tgatctgatt
     4501 gctattcgtt gtattttaga tacccaaagt gatgtttatg ccatgcttgg ttacgtgcat
     4561 gaattttgga aaccgatgcc aggtcgcttc aaagactata ttgccaaccg caaggccaat
     4621 ggttatcagt ctatccatac gactgtttat ggaccaaaag ggccgattga attccagatt
     4681 cgaaccaagg aaatgcacga ggtggctgag tacggggttg cggctcactg ggcttataag
     4741 aaaggtataa aggggcaagt taacagcaag gaatcagcta ttggaatgaa ctggatcaag
     4801 gagatgatgg agctccaaga ccaggctgat gatgctaagg aatttgtgga ctctgttaag
     4861 gaaaactatt tggctgagga gatttacgtt tttaccccag atggagctgt ccgttccctt
     4921 cccaaagatt caggaccgat tgattttgcc tacgaaatcc ataccaaggt cggtgaaaaa
     4981 gcaactggtg ccaaggtcaa tggccgcatg gttccactga caaccaagtt aaagacaggg
     5041 gatcaggttg aaattatcgc caacccgaac tcctttggac ctagccgtga ctggctcaat
     5101 atggtcaaga ctagcaaggc gcgcaataag attcgccagt tctttaaaaa ccaagataag
     5161 gaattgtctg tcaacaaggg tcgtgagatg ctgatggctc agttccaaga aaatggctat
     5221 gtggcaaata aatttatgga caagcgccac atggatcaag ttctgcaaaa gaccagttac
     5281 aagacagaag actccctctt tgcggccatt ggttttgggg aaatcggtgc gattaccgtc
     5341 tttaatcgtc tgactgaaaa ggaacgccgt gaggaagagc gtgccaaggc caaggctgag
     5401 gcagaggagc ttgtcaaagg tggcgaggtc aaggttgaaa ataaagaaac tctcaaggtc
     5461 aagcatgagg ggggagtggt tattgaaggt gcttctggtc tcctagtgcg gattgctaag
     5521 tgttgtaacc ccgtgcctgg tgacgatatt gttggctaca ttaccaaggg tcgtggtgtg
     5581 gctattcacc gtgtggactg tatgaacctg cgtgcccaag aaaactacga gcaacgtctc
     5641 cttgatgtgg aatgggaaga ccagtactct agctcaaata aggagtatat ggcccatatc
     5701 gatatctacg gtctcaaccg tacaggactg ttgaacgatg tactgcaagt tctttcaaat
     5761 acaaccaaga atatttcaac ggtcaatgcc caaccaacca aggatatgaa gtttgctaat
     5821 atccatgtgt ccttcggtat tgccaacctc tctacactga ccacggttgt cgataaaatt
     5881 aagagtgtgc cagaagttta ctctgtcaaa cggaccaacg gctagttgtc ctagctctta
     5941 ctagaaaggc tattatgaaa atcattatcc aacgggttaa aaaagcccaa gtgagtatag
     6001 aaggccagat tcagggaaaa atcaatcagg gacttttatt gctggttggt gttggaccag
     6061 aggaccaaga ggaagatttg gactatgctg tgagaaaact ggtcaatatg cggatttttt
     6121 cagacgcaga aggcaagatg aacctgtctg tcaaagatat tgaaggagaa atcctctcta
     6181 tttctcagtt taccctcttt gcggatacta agaaaggcaa tcgtccagcc tttacagggg
     6241 cagctaaacc tgatatggca tcagacttct atgatgcttt caatcaaaaa ttagcgcaag
     6301 aagtgcccgt tcagacaggt atctttggag cagatatgca ggttgagctg gttaataacg
     6361 gacctgttac cattatccta gatactaaaa agagataaga aagaccaagc ccagtcggct
     6421 tggtctttct catctatcat aaaatactcc aaaaagaaat cggttcttga tatgcttggg
     6481 ggaagtctct tttcaggctt tggcagatgc gataggaagg gatgagatgt cctaggatga
     6541 ggagagttcc ctgaaggaaa agtggaatat cacttaaaga caccaaggag agaatcatca
     6601 ggctatccca taggagaatt tgtaaagcaa aacgccagaa tctcggtcta atctgggaat
     6661 agagttaact aaagtggtca caaagttggt ttgaaagata ggtcaatagc acaggatgaa
     6721 agaaaatgag ccaaccgcta taaatcaaaa tccagtccca agtaagcccc cttttaaatg
     6781 tcaaaaatgc cagcatgatt ccatcaatga caaggagttg aatggttttg atgaagatga
     6841 tttttttcat gctaaaacct ccttttcctt agagacactc ccataaagag atgtgtttgt
     6901 cgtaaaagtc tggatagttt tctcttaggt agtcagctgt catataataa aaagtagaat
     6961 ggcaagcagt gataattgac ataagagatg aaaaacgctg agaactaatg aaggctaaga
     7021 gaacaaaaaa tagaaaatca atggtgagaa cccctaaata gtagaagcga atctttttat
     7081 tgatttgagg ataaatctca gcgaattgat gtttgagtcg gacgatcaag agaaatagca
     7141 ggagtccttg agcaaggaag aaaattaaac cagagagcaa gagccactca aaagatgtct
     7201 cgagtctaat gataaaaaat gcaaatagta gcaaatcaat aactgcaatt gctataaaat
     7261 ggattctata gagttttttc atgacaagac ctccctcttt tatctaactt cattctactc
     7321 caaaagaatg ggagttacaa ctaaaatgat aaaaatagca gaagggagat tctcttaagt
     7381 tggctagtat tctttatttg agtttccttc tattatctaa cttcttcatc attccagaca
     7441 aataaagctc cgattgcatt gaggatataa aagatgtatt taccgatatt ggcgaagttt
     7501 ccttgaatac cagcttttgt cagctgaacg aaattgtaaa tcaaccaaaa gccccactga
     7561 gttgttagtt ttaatgcatt caaagcattg gcaatgaggg atagtgcaaa ggcaatagtt
     7621 gttacgtagg caaggagatt catcttgccc tcatatccga tatagttggt cacaaaggca
     7681 aagaggaagg cgatgatgga aatgatgatg accgccaatt ttacctgttt ttggcttatt
     7741 tggttgggtc tgccttcttg cgaagctttc catttcttta tagcaaaggt ataaatgagg
     7801 aaggtgacgg gataggtaat gatggccgcc ttatttccaa ggatataatc aatagcaccg
     7861 gacaaaatgg tattaacaat accaaagtaa tttccccatt tgcttaattt ccccgtgaaa
     7921 cgagtggaca acatggaaat cccaacgttg gttacggaaa tcaatccaaa gggtacaaga
     7981 gctgtccata gtccccagtc tacaaattta tcgaggcgtg agttgagata accagatgca
     8041 atcgcaatcc caacgaccaa agcaaccccg aagaggtcaa accatttaga tgtagcaaaa
     8101 atttttagtg attttttcat aggttaaact acctttcttt ttttttcaaa tattctacca
     8161 ccaaatgaaa gtaaaataaa atgatagaaa taaaaccctg aaaataaaac tttcagggtt
     8221 ggtaggggac ttgagaaatt agttgatttt ctcgacatag agttgttttg caatgaccat
     8281 attcacttgt aaatcctcgt cgttactgag gatagtgaag gtattgctga agccatcaaa
     8341 ctgcttgact tggagctggt caccgatgtg aagtgagtgc ttgtccagat aatggagaat
     8401 gtcaaaacta tcgtgcaccc gagtcaggcg gtaggcgcca gcttccttga tatcagctag
     8461 tgggaggtta ttgatttcaa cgaggagttc tcccttggca ggaatagttc ctccgtgggg
     8521 gcaggtttta gggaaaccta gcagtttatc tagtctttcc acgaacaggt cagagacagt
     8581 gtgttccaag acctcagctt cctcgtgaat ctggtcactt gtatagtcta aatgatgaac
     8641 tagaaaaact tcaatcaagc ggtgcttacg atagagctca gagaccagtt tgagaccgag
     8701 gtcagtcagt agatagccac attccttgtc ctttaggatg agattttcac ttttcattcg
     8761 tttgatcatt tcagttacgg cagggggaga gacttgcatg cgagccgcaa tttccttgtt
     8821 ggtaatctta tgcaggtcta tgccaatttc ataaatacat tttagatagt cttctttgtt
     8881 tggggtcatt cgtttcctct tgtctaatat ctttatctag tatatcaaaa aaagctagat
     8941 ttctctagct gtgacttttt atgttatact tattgcaaga gaaaaaacga ggagatggat
     9001 atgacgaaaa tagctcttct ttcagatatt catggaaata ccaccgcctt ggaggctgtt
     9061 ttggcagatg ctcggcagct aggagtggat gaatactggc ttttgggaga tattctcatg
     9121 ccagggacag gacgtagaag gattttggac ttgttggatc aactaccgat tacggctaga
     9181 gttttgggaa actgggaaga cagtctttgg catggtgtcc gtaaggaatt ggatagtact
     9241 cgccccagtc aacgctatct cttgcgccag tgccagtatg ttttagagga aatttcccta
     9301 gaagaaattg aagtgctcca caatcaacct cttcaacttc atcgtcagtt tggggatttg
     9361 acggtgggaa ttagccatca tctgcctgat aagaactggg ggcgagagtt gattcatact
     9421 ggcaaacaag aggagtttga ccgcttggtg actcatcctc cctgtgatat tgctgtttat
     9481 ggacatattc accagcagtt gcttcgttac gggactggtg ggcaattgat tgtcaatccg
     9541 ggttcgattg gccaaccttt ctttttggac gctcagctac ggaaggactt gcgggcccag
     9601 tatatgattt tggagtttga tgacaagggc ctggtagata tggacttccg acgggtagac
     9661 tacgatgtgg cagctgaatt gcagctggct aaagacctga gacttcccta ttttgaggtt
     9721 tattatgaaa gtctggtcaa tgggatccac catactcatc atcaggaatt tttgagagaa
     9781 ttggctcaga aagagggctg cgatcgggag ttagacgact ggttgaaaag tggtaacgat
     9841 tgacattaca actaaaaagg gtataataat agaaaaagaa gagtagaggc agggtagcct
     9901 cgtaaaaagg agaagaggat gcaaattcca agtagattta ccattgcgac tcatatgctg
     9961 ataatcattg ccctcgaggg gaaggaaagc aaggtgacca gtgattttct ggctgctagt
    10021 gtcggggtca atcctgtcat tatcagaaag atcttgtccc agttgaagaa ggcagagctg
    10081 atttcagtag cgcgtggaac gggcggaaca gagattgtca aggaccttaa ggatattagt
    10141 cttttagatg tttatcaggc ggtcgaatgt cttggtaaga caggtcaact cttcagtttc
    10201 catgacaatc cgaatcccaa ttgccctgta ggagctcata ttcatgatgt tttggatcaa
    10261 aaattggaga gaattcagtt gactatggag gcagaacttg gtcagaccag tctagaaaaa
    10321 gtcgtggccg atgcagagag tcagatgaag gattaagagg gataaatgcc ctcttttttt
    10381 ctttggataa ttatgataaa atgtagctat taaaggagta agaaatgtat cttgttatag
    10441 gaattgtatt agcctttata gtgtcatttt ggaaggataa tagaagtttg tggaatccag
    10501 tattattttt attatccttc atttcaagtt atttttatct atcctacctt ttttataaaa
    10561 atggatacga gaatgttcag ttagcttttt atgtatttgc ctttgtctta cttccttttt
    10621 tgctttttct aagtggcatc tttttaatct ataatggggt cattttgttg aaacgagagg
    10681 gacgttccaa gccccattat ctctcaatgc tctttgattt ttattgacta ttagattcta
    10741 tttaaaaaga cttagaatgc acatgaaagt atgtattcta ggtcttttgt tttgtataca
    10801 tttaattttc aagagtatta tctatttttc catgcatggt aacgagtatc aatcaataac
    10861 tgggtaaggc gacccaaggt ttctctttct tttggagtga gggattgagc ttggacaaag
    10921 agatgatgaa tgtattcaag cgcctttaag gaagccaagt cattgataga gctaatacca
    10981 gcatcaagaa tagtgccaaa gaagaggtcg aagtagagct gaagttcttc gtcagggact
    11041 gtggccaccc attctttaaa ggttgtgtct acttgccggc tatcactgtt ggtcttatcc
    11101 agttgaacga agtgcttgtc ctcaatctgc caactaaagg tatcgtgctg ggcgatgcca
    11161 cccagggcag tactctgaac gatgatttgg tgagcaggaa tttccagcat cataccgata
    11221 atggaacctt gtggaatgaa tatcttgctt ctatccatta tcctttgata acccgcagtc
    11281 tgtgtcaatt cttgatggag accaggtgca tcaaatgtat aaactgctgt gatctgattt
    11341 tgcaaacttt gctcaatttg gctagcagca tagatagcga gatttcctcc cttggaatgc
    11401 ccagccagaa taaccttttg cttaggatga tgggcaaaaa agttctttaa atagcgaagg
    11461 gcgtgctttt gagaaggaat ttccttcata taggtcaggt ggaaatcttc cttccagcca
    11521 atgatactgt catctgtccc acgaaagaca atcagatagg tatcgaggct gacacgataa
    11581 gtcatagccg caaattgctt ttgcagttca gggtcgatgt cgttgataaa atgggagagt
    11641 ttgcaatttt tgaagcgctt gtgttgagcc aattcatcta ataattgaag gcgatttttg
    11701 ctagtaagca tggtgggctc tcttggaacc tgaggtgcta gatctaaaag acgttgagga
    11761 agtgtggaga ccagattatc aaaggagagg taggtgattt ctattaaggt tagaatgtct
    11821 aactcattca agggaaggtc gtaataagaa tcatatgcga catctttcag atagtcaaaa
    11881 atattggcca taagagctcc tttcttttta tttatcttag caaatttccc tcaaattagc
    11941 tagtagcata gcctgtttgt gctggctaaa aacaggctat ttcaaattca gtttcagacc
    12001 atctagcatg gaaaaatctg ttataataat ggaaaaggag aagcgcatgc acaagatttt
    12061 attaatagaa gatgatcagg tcattcgtca acagattggg aaaatgctct ctgaatgggg
    12121 atttgaagtg gtcctggtag aagactttat ggaagttttg agtctatttg ttcagtcgga
    12181 acctcatctg gtcctcatgg atattggttt gcccttgttt aatggttatc actggtgtca
    12241 ggaaatccgc aagatttcca aggtacctat catgtttctt tcttcgagag accaggctat
    12301 ggatattgtc atggcaatca atatgggggc ggatgacttt gtgaccaagc cttttgacca
    12361 gcaggttctt ttagctaagg ttcagggctt gttgcgtcgt tcctatgagt ttgggcgtga
    12421 tgagagtttg ctggaatatg ctggtgttat cctcaatacc aaatccatgg atttacatta
    12481 tcaagggcaa gtcttgaatt tgaccaagaa tgaattccag attttacgcg tgttatttga
    12541 gcatgcaggc aacatcgtag cacgtgacga cctgatgcgg gaactttgga acagtgactt
    12601 tttcattgat gataataccc tctctgtcaa tgtggctcgt ttgcgtaaaa agttggagga
    12661 gcagggattg gtaggattta tcgagaccaa gaaaggaata gggtatggat tgaagcatgc
    12721 ttgattggaa acaatttttt ctagcctatc tgcgctcccg tagtcgtctt tttatctatc
    12781 tgctttcttt ggcatttctt gtcttactct ttcagttttt atttgccagt ctaggaattt
    12841 acttcctcta ctttttcttc ttgtgttgct ttgtaaccat attatttttc acttgggaca
    12901 tattggtgga aacgcaggtc tatcgccagg aacttctcta tggagagagg gaagccaagt
    12961 ctcctttgga aatagcttta gcagaaaaat tagaagcgcg tgagatggaa ctctatcagc
    13021 agaggtcaaa agcagaaaga aaactgacgg atttgctgga ttactatacc ttgtgggtcc
    13081 atcagataaa gacccccatt gcagccagtc aactcttagt tgcagaagtg gtcgaccgcc
    13141 aactgaagca gcagctagaa caggaaattt tcaaaatcga ctcctatacc aacctagttt
    13201 tacagtacct gcgtttagaa agtttccatg atgatttggt cttaaagcag gttcaaattg
    13261 aggacttggt caaggaaata attcgtaaat atgctctttt ctttattcaa aaaggcttaa
    13321 atgtcaatct acatgacctt gataaagaaa tcgtgacgga taaaaagtgg ctgctagtgg
    13381 ttattgagca aatcatctca aacagtctca agtacaccaa ggaaggtggt ctggagattt
    13441 atatggatga ccaagagctt tgtatcaaag atacgggaat cgggataaaa aacagtgatg
    13501 tcctccgagt atttgaacgt ggcttttcag gatacaatgg ccgtttgacc cagcagtcct
    13561 ctggacttgg cctttatcta tctaagaaaa tttctgaaga actggggcac cagattcgta
    13621 tcgagtctga ggtcggaaaa ggaacgacag tgcggattca gtttgctcaa gtgaacttag
    13681 tccttgagta aaaatagatg agaaaaagcc tccagattgg aggcttttat gctagactct
    13741 tatttctcaa cgcgtgattt gttggcgata tcagctagga tagcttgaac aaaattatca
    13801 actgagacag tttgtgtttc tttttggccg tagcgacgaa cgttgactgt ttcgtcttcc
    13861 atttctttgt ctccaacaat taattggtaa ggaatcttgc tagtttgtga agcacggatc
    13921 ttgaactgca ttttttcatt gcgctcatct acgtctgcac ggacaccgcg gtcacggagt
    13981 ttcttggcta cttcccaagc gtagtccacg tgtttttcgt tagatactgg gataagggtt
    14041 acttggtgtg gtgccagcca tgttgggaag gcacccttgt agttctcaat caagatagct
    14101 gtgaagcgtt ccatagttga gataacccca cggtggatca tgactggacg gtgatcttcg
    14161 ccatcagctc cgatgtattt gaggtcgaag cgttctggca acaagaaatc aagttggata
    14221 gtagaaaggg tttcttcttt tccaagggca gttttaatct ggatatccaa ttttggtccg
    14281 tagaaggctg cttcaccttc ggcttcaaag tagtccacgc ccatttcatc aagggctgca
    14341 cgaagcatgg tttgggcatt ttcccacatc tcatcgttat caaagtactt atgagtatct
    14401 tgagggtcac gaagagagag gcggaagcgg tagtcagtca agttgaagtc ttcataaaca
    14461 tcgataatca actgaagggc acgttggaat tcttcttgga tttgttctgg agtaacgaat
    14521 aggtgaccgt cgttgagtga catttcacgt acacgttgaa ggccagtgag ggcaccagat
    14581 ttttcgtaac ggtgcatcat accgatttca gcgatacgga ttggcaattc acggtaagag
    14641 tgaacatggt gtttgaaaac ttggatgtgg tgcggacagt tcattggacg aaggacaaat
    14701 tcttccccgt cacccatgtc catggttggg aacatgtctt cttggtaatg atcccagtgg
    14761 ccagaagtct tgtaaagctc aacagaagca agtggtggag tgtagacgtg ttggtagcca
    14821 gaagccaact ctttgtttac gatgtagcgt tccaattcac gacggatagt cgcaccattt
    14881 ggcaaccaga atggcaaacc ttgtcccact tcttgtgaaa tcataaagag gtcaagctct
    14941 ttaccaagtt tacggtggtc acgttcctta gcttcttcac gcatttgaag gtagtttttc
    15001 aagtctttct tgtcaaacca agctgtaccg tagatacgtt gcatcatagc gttgtcgctg
    15061 tttccacgcc agtacgcacc agctacatgg agaaggtgga agatttggat acgacctgtt
    15121 gatggaacat gaggtccacg gcagaggtct acatattcac cctgacgata gatagtcaaa
    15181 ccgccttcgt cttctgagtg ttcttcaatc aattccaact tgtaagggtc atttttgaag
    15241 atttcacgtg cctcgtcttt agtcacttct tcacgaatag atgggaagtt ttctttgacg
    15301 attttttgca tttcttcttc gatacgagga aggtcttcgt tagagatttg accagctgtg
    15361 ttgtcagtat cgtagtagaa accatcttcg atggctggac caactcccaa gtgaatgtct
    15421 gggaaaagac gacgagctgc ttgggcgaac aagtgagctg ctgagtgacg caagattgga
    15481 agggcatctt cgtgatcagg tgtcacaatt tcgatgcttc catcttcagt gatagcgcga
    15541 gtagtgtcga tgagtttgcc gttgaattta ccagccaagg cttttttagc tagggaattg
    15601 ctgatagatt gggcaatttc aaaagttgtt acgccagatt cgaattcacg aacagcgcca
    15661 tctgggaaag taatgttaat catgatgttc tcctttttta ttatttcata gtttctaagc
    15721 attgattttt tatcagcaga ctacttccaa gtcctaacgt tcaattgctt ttctttatca
    15781 gagaggaagt tttccatttc cgtcagaatg tctatatcca aacgttgaga aagttctaat
    15841 agtcaccaga tattttctga aagtttttgt tccagtgtgt agggtgtttc atcatagtag
    15901 cgtccttgtt ttgtcatcac cagtcgttgg aaatttccaa tatcattaga taaagccaag
    15961 aggtcttctt ctaccgtcca cttggaatca tgatgcttaa cttccagttc gttataagct
    16021 tgtcggattg cccaactgcg ctccactaat tcttgcaact ccataattag tatcctaata
    16081 aaaaaatgcg acatcctcga aaggacgtcg caacgtggtt ccaccttcat ttatgtacct
    16141 caaaagagag ggacacctct gattggctct aacgtggcca ccgttttatg ttttcataaa
    16201 aaactcaaga gtagtatcag tttagacttc ctatgcgttt ccagcaacca cgcactctct
    16261 agtagaaagg gactaagtga cttgtctcta tggattatta tagcatgatt gtgagatttt
    16321 tcaaggattt tgtgaaagtt ttttgttttt cattttttgt agaatatgct tgatgctaat
    16381 accagaatcc atgcccacca gagcaactgt ttcatagatt agcaagtaaa ttagtataaa
    16441 ctcaccaaag gttatgatag taaagtaaaa gagcagtccg ttaccaacta accatcaaag
    16501 tgagaaacgg aaacggtagc tatagagtaa cgatacaatc aagattacca gaggtgtaaa
    16561 gaagagaaga ttgtttatat agtgtaaggg ggtcagaaac aactagcaag aacaactcat
    16621 aaagtggcca ataaaagaat aatatgacca gatagtaggg gagatgggaa tagaatctac
    16681 gcatgataat cacctcgttt taaaaaaaca gacaacttag atctcttgct atgattatta
    16741 tagcatattt aaaacaagaa agtaaatttg ttgacaaaga agattttttt tcactagaat
    16801 catggttagt tttcttggta gaaatatttt gataataatt aagcaagact attgacattg
    16861 attattaaga gtgtcacaat tgctgtaact aaaataatta caacaagaga ggtataaaaa
    16921 atgaaactag cagttattgc agcaaatgga caagcgggga aagcaattgt tgaagaagca
    16981 gtcaaacgag gacatgaagt aacggctatt gttcgttctg aaaacaaaag tcaagctgag
    17041 tctattatta aaaaagattt atttgagttg acaaaagatg atcttactgg atttgatgct
    17101 gttatttcag cgtttggtgc ttatacacca gatacgctac cgctccatag caaatcaatc
    17161 gaactattta atcagcttct tgctggaaca cagacacgtt ttctagttgt agggggagca
    17221 ggaagccttt atatagatga aacaaaaacg acacgacttt tagatacgcc tgattttcct
    17281 gaagaattta agccactagc aaaagctcaa gcggatgaat ttgatcttct tcgtacaaaa
    17341 aataatctca actggacttt tgtcagtcct gctgtagatt ttattcccga tggtgaaaaa
    17401 acaggaaact acattctagc aggagaaatt tttactacta atggaaaagg aataagccag
    17461 attagttatg cagattatgc tattggattg gtagatgaac ttgaaaaagg tcatcatata
    17521 aaagaacgta tctctttact tgaaaaataa taactatgag agtattaatg tttgacagaa
    17581 aatttaaatc ttggtaaaat agggattgtc gtaaagacaa ataacttctt cttggttaca
    17641 ggcatgccaa cctgtcactc ggatgaagcc aaataaaaag gagaaacatc atggcaatct
    17701 caaaagagaa aaaaaatgaa atcattgcac aatatgcacg tcacgaaggt gatacaggtt
    17761 cagtagaggt tcaagttgct gtccttactt gggaaatcaa ccaccttaac gaacacatca
    17821 aacaacacaa aaaagaccac gctacttacc gtggattgat gaaaaaaatc ggtcgccgtc
    17881 gtaacttgct tgcatacttg cgtaaaaacg acgttaaccg ttaccgtgag ttgatcaact
    17941 ctctaggact tcgtcgctaa ttcaagatac aaaggccgtc aaaagcacaa agcaaaaata
    18001 ggaaaattga cgaagaaact tcagtttcta ggagatttta tcttttttgc caagtgctta
    18061 ggccgtgttc aattgagcat atcttgataa tgaagctact ctaaattggg tagctttttt
    18121 gcgttgtcac cttacctcga tatactcaag tataatcttt ggttacggtt cctagcactg
    18181 taaggtaaaa taaaccagct tttctccctt cggggagatt ttttttgttt cactgaaagt
    18241 ttcgtacgat cttcgcctcg tcgcctagtc tataaacgat ttatctagca agaatcatga
    18301 tgctaagggc gtcaaaaatc cgtatgaaaa tagggaaatg acacagtgtt cgatgagcac
    18361 aaggagtttc atctttttca ctaggatttt agcccgggct caaatcagct ctctgacttc
    18421 agagggcttt tttattgagg ttttatcggt aacaattttg gagactacaa aaacctcaaa
    18481 cggtatcagc taattacacc ataaaggtgc gcagttactc ggcttttcaa gccgagtaac
    18541 tgtatgcaag cccctagaag agcccactct ttacaaagta aagtatagta tgttatactt
    18601 tacatggaag tagtcactga attccagtta gaaattactt tgtaactacg ttttgaggag
    18661 gagtaaaatg ctttcctacg ttcgacatta cccactagcg atagctaaat taatgtgtct
    18721 gtgctctcct aaaatctgct gatttattac tgactaatac aggagttttt ttttatggga
    18781 cagacaatca tatctgctat tggtgtttat atttccacca gtatcgatta tttaattatt
    18841 ttaattattt tatttgcaca gctatcacag aataaacaga aatggcatat ttatgcgggg
    18901 caatatctag gcacaggctt acttgtaggg gcgagtttag ttgctgctta tgtcgttaat
    18961 ttcgtgcctg aagaatggat ggttggattg cttggtttaa tccctatcta tttagggatt
    19021 cgctttgcaa ttgttggaga agatgcggaa gaagaagagg aagaaattat tgaaagatta
    19081 gaacaaagca aggcaaatca actgttttgg acagttacat tgctgacaat tgcgtctggc
    19141 ggagataatt taggtatcta tataccttat tttgcttcgt tagattggtc acagaccctc
    19201 gtggccttgc ttgtgtttgt aatcggcata attatctttt gcgagattag tcgggtgtta
    19261 tcctctattc cgttaatatt cgagacaatt gaaaaatacg agcgaatcat tgtgccctta
    19321 gtattcattc tacttggact atacatcatg tatgaaaatg gcacgataga gacttttctg
    19381 atcgtgtaga tttttttgtt tcactaggat tttagcccga gctcaaatca gctctctgat
    19441 tttcagaggg ctttttcatt gagtataaat ggacaatctt aaagttactc tattgtagag
    19501 tggcttttga tttgattagg agattcttat aaatatagta aaatgaaaca aaaacaggac
    19561 aaatcgatca ggacagtcaa atcgatttct aaaaatgttt taagaagtag aggtgtacta
    19621 ttctagtttc aatttgatat ataaatgaaa accttagctg tttggccaag gttcatttct
    19681 tctatgcaag ttcttctctt ttcttatctg ggttccagat gaagcttgcg ataaagctaa
    19741 agatgatggt taggatagcg aggataatag caaggatgag ggcagggatg cggataaacc
    19801 accagagtgg atttggtttt ttatcattgt gccattgttt cgtttcttcg tccagacgtt
    19861 ggaattctgt ttgaatacga ttggcgactg tttcaatgcc ttcatcattc attttcttga
    19921 tatctgagat atcgattgga tttccaaagt tcatatcgac acgttcacgg ctaatcaagc
    19981 ccttcaaagt catgggaccg gtgtaggtaa ccggcatgat acggaccttg gccattttgg
    20041 caatcagtgc tgcgcccccc ttgacatcgt ttgagtggcg gctaccactt ggaaacatga
    20101 tgagagagcg gtcacttttt ttgagaacgt tgataggata tttgatggct gaggcgctgg
    20161 gattttcacg gtcgatggga aaggcgccac acatacgaat ccaccaacca aagatacggt
    20221 tggtaaagag ttcttttttt gccataaaga tgaactgttt tggcttggtc gcaaaggcca
    20281 tataaacagg atcccaccag gtacggtgag gcgcaactaa aatataattt tcatcttgat
    20341 taggaatttt atcagtatta tgatagtgag cattgccatt gatggaccat aagagcaata
    20401 caactaatcc acgcaaataa gtataaaaca tgcgatctcc ttcgattgtt ttcttgttat
    20461 tattatacct tatcaaagga gggctggcaa acttttccct tgactagatg catatttggg
    20521 atgaaattag aattctgtta aaaaaaatga tataatagaa tttatggata aaaataagat
    20581 tatgggatta acccaaagag aagtcaagga aagacaggct gagggtttgg tcaatgactt
    20641 taccgcatca gccagtacca gcacttggca aatcgttaaa cgaaatgtct ttaccctttt
    20701 taacgctttg aactttgcca ttgctttggc ccttgccttt gtgcaggctt ggagcaatct
    20761 ggtcttcttt gctgttatct gctttaacgc tttttctggg attgtgaccg agctacgagc
    20821 caaacacatg gtggacaagc tcaatctcat gaccaaggaa aaggtcaaaa ccatccgtga
    20881 tggtcaggaa gttgctctta atcctgaaga attagtgcta ggagatgtca ttcgtttgtc
    20941 tgcaggagag cagattccta gtgatgcctt ggttttggaa ggctttgcgg aagtcaatga
    21001 agccatgtta acgggagaaa gtgatttggt gcaaaaggaa gttgacggct tacttttgtc
    21061 aggaagtttc ctagccagtg ggtcagtttt atctcaagtt caccatgtcg gtgcagacaa
    21121 ctatgctgcc aaactcatgc ttgaggctaa gaccgttaaa cccatcaact cccgtatcat
    21181 gaaatcgctg gacaagttgg ctggttttac tgggaagatt atcattccct ttggtctggc
    21241 tctcttgctg gaagccttgc ttttaaaagg cctgcctctc aagtcatctg ttgtaaattc
    21301 gtcgacagct cttttgggaa tgttgcctaa gggaattgcc cttttgacca ttacttcgct
    21361 tttgactgca gtgattaagc taggtttgaa aaaggtcttg gtgcaggaga tgtactctgt
    21421 tgagaccttg gcgcgcgtgg atatgctctg tctggacaag acgggcacca tcacccaagg
    21481 aaagatgcag gtggaggctg ttcttccact gacggaaact tacggtgaag aggctattgc
    21541 cagcatcttg actagctaca tggcccatag tgaggataaa aatccaacag ctcaagccat
    21601 tcgccagaga ttccaaggtc aagtagtcta tcctatgctc tctaatcttc ccttctccag
    21661 cgaccgcaag tggggagcca tggagttaga aggtttggga atagttttct taggggcacc
    21721 tgagatgttg ctggattctg aggtcccaga agccagagag gccttggaga gaggttcacg
    21781 tgtcttggtc ttagctctca gtcaggagaa attagaccat cacaaaccac agaaaccatc
    21841 tgatattcag gctctagcct tgctggaaat cttggatcct attcgagagg gagcggcaga
    21901 gacgctgaac tatctccgtt ctcaggaagt ggggctcaag attatctctg gtgacaatcc
    21961 agttacggta tccagcattg cccagaaggc tggttttgcg gactatcaca gctatgtcga
    22021 ttgttcaaaa atcacggatg aggaattgat tgctctggcg gaggagacag cgattttcgg
    22081 acgtgtttcc cctcatcaaa agaaactcat tatccaaacg ctgaaaaaag cgggtcatac
    22141 aacagctatg actggggatg gagttaatga tatcctggct cttcgtgagg cggattgttc
    22201 tatcgtaatg gcggagggag acccggcaac ccgtcagatt gccaacctgg ttctcttgaa
    22261 ctcagacttt aatgatgttc ctgagattct ttttgaaggt cgtcgtgtgg tcaataacat
    22321 tgcccacatc gctccgattt tcttgataaa gaccatctac tcattcttgc tcgcagttat
    22381 ctgtatcgcc agtgctttac taggtcggtc tgaatggatc ttgattttcc ccttcattcc
    22441 aatccagatt accatgattg accagtttgt ggaaggtttc ccaccattcg ttttgacttt
    22501 tgagcgaaat atcaaacctg tcgagccaaa cttcctcaga agatccatgc ttcgtgccct
    22561 accaagtgcc ctcatggtcg tgtttagcgt tctttttgtg aaaatctttg gaacgagtca
    22621 aggttggtct gagttagaaa tctcaactct cctctattat ctcttggggt caattggttt
    22681 cttatccgta tttagagcct gcatgccatt cactctatgg cgagtcctat tgattgtctg
    22741 gtcagtagga ggcttcctag ccacagctct cttcccaaga attcaaaaac tgcttgaaat
    22801 tgcaacctta acagaacaaa cgttgcctgt ttatggtgtc atgatgttgg tctttacagt
    22861 gattttcatc ctgactagtc gctatcaagc tagaaaataa agaaagactg caatctgtgg
    22921 attgcagttt ttttaggtac aagattgcca gccgaaatgt ggtataataa gaggtaatag
    22981 agttttggaa agtgagagaa gatgatttca aagagattag aattggtagc ttcctttgtg
    23041 tcacaggggg ctattttact agatgtggga agtgaccatg cttatctgcc tatcgagttg
    23101 gttgagagag gccaaatcaa aagcgctatt gcaggtgagg tggtggaagg tccctatcag
    23161 tctgcggtta aaaatgttga ggctcacggc ctaaaggaga aaatccaagt ccgtttagcc
    23221 aatggcttgg cagcttttga agagactgac caagtgtctg tcattaccat tgctggcatg
    23281 ggtggtcgtt tgattgctag gattttagaa gaaggtttgg ggaagttagc taatgtagag
    23341 cgtttgatcc tccagcccaa taatcgtgaa gacgacttgc gtatctggct acaggatcat
    23401 ggattccaga ttgtagcaga aagcatctta gaagaagctg gcaagtttta cgagattttg
    23461 gtggtggaag caggacaaat gaagctatca gccagtgatg ttcgctttgg tcccttcttg
    23521 tccaaagaag tcagtccagt atttgtccaa aaatggcaaa aagaagctga gaagctagag
    23581 ttcgccctcg gacaaatccc agaaaaaaat ctggaagaac gtcaagttct agtagataag
    23641 attcaagcta tcaaggaggt gccccatgtt agcaagtgaa gtgatccaag cttatgaagc
    23701 cttttgccct caggaatttt ctatggaggg agacagccgt ggtctgcaaa ttggcacttt
    23761 agacaagggt atccaaaggg tcatggttgc cctcgatatt cgtgaagaga cagtggcaga
    23821 ggccattgaa aagggtgtgg acttgattat cgtcaagcac gcgcctatct ttcgtcctat
    23881 caaggacttg cttgccagcc gtccgcaaaa tcagatttac atcgacctga ttaagcatga
    23941 tatcgcagtt tatgtcagcc ataccaatat tgatatcgtt gaaaatgggc tcaatgactg
    24001 gttttgtcag atgctaggaa tcgaggagac gacttatctg caggaaacag gtccagaacg
    24061 tggaattgga cgtattggga atattcagcc tcagacattt tgggaattgg cccaacaggt
    24121 caagcaagtc tttgacctag atagccttcg aatggtgcat tatcaagaga atgatttgca
    24181 gaagcctatt tcaagagtag caatttgtgg tggaagcggg cagtctttct ataaggatgc
    24241 tttggcaaag ggggcagatg tctatatcac tggcgacatc tactaccata ctgctcagga
    24301 tatgctgtct gatggcttgt tagcattgga tccaggtcac tatatcgaag tgctttttgt
    24361 ggaaaaaatc gcagcactcc ttactcaatg gaaagagaaa aaaggctggg aactagagat
    24421 tttacctagt caagcatcga ccaatccttt ccgtcatatc tagttagaaa gtgaagacaa
    24481 tgaaaaaagt tgccattatt ggagcaggaa ttgtgggagc aacagctgcc tactacctct
    24541 cgagagaaag tgacttagag gtgaccgttt ttgaccatga gcaaggtcaa gccaccaagg
    24601 ccgcagcagg aattatcagt ccttggtttt ccaaacgccg taataaagcc tggtacaaga
    24661 tggcgcgctt gggggctgat ttttatgtgg atttattagc tgatttagag aaatcaggac
    24721 aagaaatcga cttttaccag cgttcgggag tctttctttt gaaaaaggat gaatccaagt
    24781 tggaagaact ttatcaactg gccctccagc gcagagaaga atctcccttg atagggcaat
    24841 tagccattct ggaccaagct tcagctaatg aattattccc tggtttgcag ggatttgacc
    24901 gcctgctcta tgcttctggt ggagcgagag tagatggcca actcttggta actcgtttgc
    24961 tagaagccag tcatgtcaag ctggtcaaag aaaaagtgac tctgacaccg ttagcatcag
    25021 gctaccagat tggcgaagag gtgtttgatc aggttatttt ggcaacggga gcttggttgg
    25081 gggacatgtt agagccttta ggttatgaag tggatgtccg tcctcaaaaa ggacaactac
    25141 gagattatca gcttgcccaa gacatggaag attaccctgt tgtcatgcca gaaggggagt
    25201 gggatttgat tccctttgca ggtgggaaat tatccttggg cgctacccat gaaaatgaca
    25261 tgggatttga tttgacggta gatgaaccct tgctccaaca aatggaggag gccaccttga
    25321 ctcactatct gattttggct gaagctactt caaaatctga gcgtgttgga atccgtgcct
    25381 acaccagtga tttctctcct ttctttgggc aggtgcctga cttaactggt gtctatgcag
    25441 ccagtggact aggttcatca ggcctcacaa ctggtcctat tattggttac catttagctc
    25501 aactgatcca agacaaggag ttgaccttgg accctgaaaa ttacccaatt gaaaactatg
    25561 tcaaacgagt aaaaagcgaa taatactcaa tgaaaatcaa agaacaaact aggaaactag
    25621 ccgcgggtta ctcaaagcac tgctttgagg ttgtggatag aactgacgaa gtcagtaacc
    25681 atacccatgg caaggcgacg ttgacgtggt ttgaattgga ttttcgaaga gtataagcat
    25741 tttactgaaa ttttatcagg tagtttagga tggcaaatga cattccctgt caaaaatggt
    25801 aaaataagaa aaaataatct gagaatcgag gaaaaaagat gcaagaaaag attttggtaa
    25861 ctggtggtgc cggttttatt ggaacccaca ctgttattga attgatccaa gcaggccatc
    25921 aagttgttgt ggtggataat cttgtcaata gcaatcgtaa gagtttagaa gttgttgaaa
    25981 gaatcacagg agttgagatt cctttctatg aggcagatat tcgtgacaca gataccctca
    26041 gagatatttt caagcaggaa gaaccgactg gtgtcattca ctttgctggt ttgaaggctg
    26101 ttggcgaatc aacacgtatc cctcttgcct actatgacaa caatatcgct ggaactgtca
    26161 gccttttgaa agtcatggaa gaaaacaact gtaaaaacat catcttcagt tcttctgcga
    26221 cagtttacgg ggatccgcac acagtgccca tcttggaaga tttcccactt tcagtgacca
    26281 acccatacgg tcgtactaag ctcatgctag aggaaatttt gactgatatt tacaaagcag
    26341 actcagaatg gaatgttgtc ttgcttcgtt actttaaccc aatcggagcc catgagagtg
    26401 gtgatttggg agaaaatcca aacggtattc caaacaatct cttgccatat gtgactcaag
    26461 tagccgttgg aaaattagag caagtgcaag tgtttggaga cgattacgat acggaagatg
    26521 gaacaggtgt tcgtgactat atccacgttg tcgatttggc taagggtcac gttgcagctt
    26581 tgaaaaaaat ccaaaaaggt tcaggactaa acgtttataa ccttggaact ggtaaaggtt
    26641 actcagttct tgaaattatc caaaacatgg aaaaagcggt gggacgtcct attccttacc
    26701 gcatcgtaga acgtcgccca ggtgatatcg ctgcctgcta ctcagatcca gcaaaagcta
    26761 aagcagaact cggttgggaa gcagaactcg acatcaccca aatgtgtgaa gacgcatggc
    26821 gttggcaaag caagcatcca aatggatttg aagactaaga tgatgatttc aatcatcgtc
    26881 ccttgtttaa acgaagagga agtacttcct cttttttatc aggctctgga agctttactt
    26941 ccagatttgg aaacagaaat cgagtatgtc tttgtcgatg atggatcgag tgatgggacc
    27001 ttggaactct taaaggccta tcgggagcaa aatccggcag cccattatat ttctttctcg
    27061 cgaaattttg gcaaagaagc agccctttat gcaggcttgc aatatgcgac aggagatttg
    27121 gtggtggtga tggatgcaga cctccaagat cctcctagta tgttgtttga gatgaaaaat
    27181 gtactagaca aaaatgtaga cttggactgc gttgggacac ggagaactag tcgggaggga
    27241 gaacccttct ttcgcagttt ctgtgctgtt ctcttttatc gcctcatgca aaaaatcagc
    27301 ccagtagctc tgccgtcggg tgtccgtgat tttcgtatga tgagaaggtc tgtggtcgat
    27361 gccattttaa gcttgactga gtccaatcgt ttttcaaagg ggctcttcgc ctgggtgggt
    27421 ttcaaaacct actatttgga ctatccaaat gtcgaaaggc aggctggcaa gaccagttgg
    27481 agttttaggc aactcttttt ctactccatt gaagggatta ttaatttttc agattttccc
    27541 ttgattatag cctttgtagc tggtctccta tcttgttttc tttctctgct gatgaccttt
    27601 tttgttgtgg ttcggaccct cattttgggc aatccgacat ctggttggac ctctctgatg
    27661 gctgttattc tctttcttgg aggcattcaa ctcttgacca ttgggattct cggaaagtat
    27721 atcagtaaga tttatttaga gactaaaaaa agaccacttt atcttatcaa agaaaaaagt
    27781 gaccttcctg attttacaga aaaaaataaa gtgaaaagac tataatttta catggaaata
    27841 tgctaaacta gagggagtgg attatcgcca ttgatttagg cttcctggtt tccaatcagg
    27901 gcgcgagttg ggcaattttt aacagcctct aagacatcct gactaggaga aatttctttt
    27961 tccagttggt cagggtcatc gtaaaaacgc acgattccat tatcgtggta atcaaataaa
    28021 tcagaataag tttggcaaag cccacaggcg atacatcgtt caggtataag tgtgattttc
    28081 atgttcatat ttatattgta ataagaaaag taaaaaaaaa caaggagtaa ggtatggcaa
    28141 aagaaccgtg gcaagaagat atctatgatc aagaagaatc aagagcagag cgtcggcatc
    28201 gaaaccacgg aggggctgat aggatggcta atcgtatttt gacgatccta gctagtattt
    28261 tctttgtaat tgtggtggtg atggtcatcg ttctcatcta tctatcatcg ggggggagta
    28321 atcgcacagc agccttaaaa gactttcatg attctgatgc aagtgtagta caaatctcat
    28381 cttcaagcag ttctcagcct gagcagagtt cagagctaga atctacttct agtagttcag
    28441 aagaagctgc taatcctgaa ggaacgatta aagttctcgc aggagaaggg gaagcagcta
    28501 ttgccgctcg tgcaggaatc tccattgctc agttagaggc cttgaatcct gggcacatgg
    28561 ctacaggatc ttggtttgct aatccaggtg atgttataaa aataaaatag gagccgatat
    28621 gaaaacaatt caaattgcta ttgatggtcc tgcttccagc ggtaagagta cggtcgcaaa
    28681 gattattgct aaggattttg gattcaccta ccttgataca ggagctatgt atcgtgcagc
    28741 gacctatatg gctcttaaga accaattagg agttgaagaa gtcgaagccc ttctagcctt
    28801 gttggaccag catccaatca gctttggacg ttcagaaact ggagaccagc ttgtttttgt
    28861 aggagatgtg gatattaccc atcctatccg tgaaaatgaa gtgaccaatc atgtttctgc
    28921 tattgcagca attcctgaag tgcgtgagaa actggtttct ctccaacaag aaattgccca
    28981 gcaaggcggg attgtcatgg atggtcgcga tattggaact gttgtattgc cacaagcaga
    29041 attgaaaatt ttcctagtag cttctgttga tgagagagca gagcgtcgtt acaaggaaaa
    29101 tattgccaag ggaattgaaa cagaccttga aaccctaaaa aaggaaattg ctgcgcgtga
    29161 ctacaaggat agtcatcgtg agacttctcc tctcaaacaa gcagaggatg ctgtctacct
    29221 tgatacaact ggtttgaaca ttcaagaagt agttgaaaaa atcaaagcag aagctgaaaa
    29281 aagaatgtaa atgtagaaaa gccgatagat tgatatcggt ttttttctaa atttgtcaaa
    29341 atgctgattt tagggtataa tagttgctgt tcgagaaatt ttgattttca aagaatagtg
    29401 aatgatgata aggagaaacc atgaacaatt taccaaattg tccaaaatgt aactcagagt
    29461 atgtctacga agacggtgcc ctactggttt gcccagagtg tgctcatgag tggaatcctg
    29521 ctgaagttgc agaagtagaa gaaggtcttg tcgctatcga tgccaacgga aataaattga
    29581 ctgatggtga tacagtaact ctcatcaagg acttgaaagt aaaaggtgcg ccaaaagatt
    29641 tgaaacaagg gacgcgcgtg aaaaatatcc gcatcgtaga aggcgaccac aatatcgact
    29701 gtaagattga tggttttggt gccatgaaac ttaaatcaga gtttgtgagg aagatttaag
    29761 catgtcaaaa cactataaac ttgtatttta tagccgtatc ttcttgtttc tagcggcttt
    29821 tacgggagtt tatcttgaaa ttactaggca tggtggtttt gggatgcttc tctattacac
    29881 ggttctgtcc aacctcttgg taactatttt taccctttat cttctaaagg ttatgagccg
    29941 tgtaggtgaa aattggcaaa ggccaagtct cttgcgctta aaaggtgggg tcaccatgag
    30001 tatcatgatt acctgtgtga tttaccattt cctcttggcg cccattgcga ctaatttcta
    30061 taccctagaa aatttccttt gccactatat cgttcccatc tggtttttag cggataccct
    30121 cttttttgac aaacagggtc aatacaagat ttgggatcca gcagtgtgga ccattttacc
    30181 ctttctgtat atgatgtttg ctctttttaa tggcttggtt ctaaaactca atattccaaa
    30241 tgccaaggat aatcctttcc cttacttctt tttgaatgtg aacaagggtt ggaatgttgt
    30301 gtttaagtgg tgtctgatta tctttgttgc ctatatggta gcaggattta ttttctactt
    30361 tatcaagcaa atcaagagaa agtcatccta atactcttcg aaaatctctt caaaccacgt
    30421 cagtttccat ctgcaacctc aaaacactgt tttgaacaac ctgcggctag cttcctagtt
    30481 tgctctttga ttttcattga gtataagata caagggattc attttcgaat ttaagaagga
    30541 gtctacaaac caatgaggct tcttcttttc ttgcttattt gataactatc aaaaaagtag
    30601 aagattaaga gaaatataga aagagatttc atgaaacaat ttttagaacg ggccagcatt
    30661 ttggctctct ccctcgtttt gattacctcc ttttccattt cgagtgctct accagccatg
    30721 tttgactatt atcagggtta ttctaaggaa caaattgagc tcttggtgag cttgccttcc
    30781 tttggaatca tgatgatgtt actgctaaat ggtttcttag aaaaaatatt tcctgagcgc
    30841 ttacagatta gtttgggctt gctgatttta tcattgagcg gtacagctcc cttctggtac
    30901 caagcctatc cctttgtctt tggaacacgg cttctctttg gtttgggtct tgggatgatc
    30961 aatgccaagg ccatttctat tatcagtgaa cgctaccaag gaaaaaggcg aattcagatg
    31021 ttagggctac gcgcttctgc agaggtcgtt ggagcttctc tcattacctt ggccgtcggt
    31081 cagttgttgg cctttggttg gacagctatc tttctagcct atagtgctgg atttttggtg
    31141 ctgccccttt atctgctctt tgtcccttat ggaaaatcaa agaaagaagt caagaaaaga
    31201 gcgaaggaag caagtcgttt aactcgagaa atgaaaggct tgatttttac cttagctatc
    31261 gaagcggcag ttgtagtttg taccaataca gctattacca tccgtattcc aagtttgatg
    31321 gtggaaagag gattggggga tgcccagtta tctagttttg ttcttagtat catgcagttg
    31381 atcgggattg tggctggggt gagtttttct ttcttgattt ctatctttaa agagaaactg
    31441 ctcctctggt ctggtattac ctttggcttg gggcaaattg tgattgcctt gtcttcatcc
    31501 ttgtgggtgg tagtagcagg aagtgttctg gctggatttg cctatagtgt agtcttgacg
    31561 acggtctttc aacttgtctc tgaacgaatt ccagctaaac tcctcaatca agcaacttca
    31621 tttgctgtat taggctgtag tttcggagcc tttacgaccc catttgttct aggtgcaatt
    31681 ggcttactaa ctcacaatgg gatgttggtc tttagtatct taggaggttg gttgattgta
    31741 atctctatct ttgtcatgta cctacttcag aagagagctt aggattgatt cctaagtttt
    31801 tcttttgata ctcaatgaaa atcaaagagc atagttgatt gagtttggaa tagtacgctg
    31861 tagttgctaa aatatttcta gaaattaatt tgacttttct aatagagtta ttcatatctt
    31921 atttcaatct actatagaaa gctagccgca ggttgctcaa aatagtgttt tgaggttgca
    31981 gatggaaact gacgtggttt gaagagattt tcgaagagta tgagattttt atacccatac
    32041 aatatttgtt ttaggtcctt gtttacagac taatttcttg ataaaataga ggttatgacg
    32101 agatataaag caactatttc ctatgatggt tatgcctttg ctggctttca gcgccagtct
    32161 catgcgcgta gcgttcagga agaaattgaa aaaaccttga ccagattaaa taaagggcaa
    32221 accattactg ttcacggtgc tggtaggaca gatagtgggg ttcatgccct gggacaggtc
    32281 attcattttg acctgcctta tcagatggat gaggagaaac tccgttttgc cttggatacc
    32341 cagtctcctg aagatattga tgtgatttcg attgagcttg tggcagatga ttttcattgc
    32401 cgttatgcca aacatagcaa gacctatgag tttattttgg atagaggacg tcccaaaaat
    32461 cctatgcgcc gtcactatgc cacccacttt ccctacccac tcgatgtgga acgaatgcag
    32521 attgcaatca aaaagctaga gggaacccat gattttaccg gttttacagc ctctgggact
    32581 agtgtagagg ataaggttcg caccatcaca gaagctagtt taatagtcga tgagacagga
    32641 caatttttga cctttacctt ttcaggaaat ggtttcttgt ataaacagat tcgcaatatg
    32701 gtggggactc ttctcaaaat cggtaacaac cgcatgccag tagagcagat tgatctcatc
    32761 ttggagaaga aggacaggaa acttgcaggt cccactgcag caccaaatgg tttgtattta
    32821 aaggagattc gttatgaaga ataatcgtat tttagcactt tctggaaatg atatttttag
    32881 tggtggtgga ctgtcagctg atttggctac ctataccttg aacggcttgc atgggtttgt
    32941 agcagtgact tgtttgacag ccttgacaga aaaaggattt gaagtctttc caactgatga
    33001 taccattttt caacatgaat tagatagctt gcgtgatgtg gaatttgggg gaattaagat
    33061 tggtcttctc cctactgtca gtgtggctga gaaggccttg gactttatca aacaacgccc
    33121 aggagtacct gtggtgttgg atcctgtctt ggtctgcaag gaaacgcatg atgtagctgt
    33181 cagtgagctc tgccaagagt tgattcgctt tttcccttat gtcagtgtga ttacgcctaa
    33241 tctcccagaa gcagaattat tatccggtca ggaaattaaa accttggaag acatgaaaac
    33301 tgcagcgcag aaattgcatg atttaggagc gccagcagtc attatcaagg gaggcaatcg
    33361 tcttagtcag gacaaggctg tggatgtctt ttatgatgga cagaccttta ctatcctaga
    33421 aaatccagtt atccaaggcc aaaatgctgg tgcaggttgt acctttgcct ctagcattgc
    33481 cagtcacttg attaaaggtg ataaactttt gccagcagta gaaagctcta aggctttcgt
    33541 ttatcgtgct attgcacaag cagatcagta tggagtaaga caatatgaag caaacaaaaa
    33601 caactaaaat cgcccttgta tccctattaa ccgccctttc tgtggttcta ggttatttct
    33661 taaaaatccc aacacctaca ggaattctaa ctcttttaga tgctggtgtc ttctttgcgg
    33721 ccttttactt tggtagtcgt gaaggagcgg tagtcggagg actagcaagt ttcttgattg
    33781 acctcttatc aggctaccct cagtggatgt tctttagctt ggtcaaccat ggcttgcagg
    33841 gatttttcgc aggatttaaa ggaaaaagtc agtggttagg ccttatttta gcaactattg
    33901 ccatggtagg aggctacgcc ttgggttcta ctttgatgaa tggctgggca gcagccctcc
    33961 cagaaattct accaaatttc atgcaaaata tggtagggat gattgtagga tttattctta
    34021 gtcaaagtat caagaagatt aagtaatact cttcgaaaat ctcttcaaac cacgtcagtt
    34081 tccatctgca acctcaaaac actgttttga gcagcctgcg gctagctttc tagtctgatt
    34141 ttcattgagc ataaagaggt tgagtaaaaa gtctttcaaa taagaaaaac gcatagtata
    34201 ggatgttgaa atgatgaact gccccccaaa agttagacag aaaaaatcta acttttgggg
    34261 tgtttttatt atgaaactaa cttatgatga taaagttcag atctatgaac ttagaaaaca
    34321 aggatatagc ttagagaagc tttcaaataa atttgggata aacaattcta atcttaggta
    34381 catgattaaa ttgattgatc gttacggaat agagttcgtc aaaaaaggaa aaaatcgtta
    34441 ctattctcct gtttaaaaca agaaatgatt aataaagtct gacatgaagg ctagactaaa
    34501 gatagagttt ctcttgaata cggtctccca agtcgtacga tacttcttaa ctggctagca
    34561 caatacagga aaaacgggta tactattgtt gagaaaacaa gagggagagt acctaaaatg
    34621 ggacgtaagc ccaaaaagag acctgaagag aggacagaat tagaacgtct tcaagcagaa
    34681 aatgagtacc tgagagcg
//
LOCUS       DBJKQU010000018        34664 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.018, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000018 DBJKQU010000000
VERSION     DBJKQU010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34664
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.018"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(22..1311)
                     /locus_tag="ACSUUC_000974"
                     /pseudo
     CDS             complement(22..1311)
                     /locus_tag="ACSUUC_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003611335.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(1292..1486)
                     /locus_tag="ACSUUC_000975"
     CDS             complement(1292..1486)
                     /locus_tag="ACSUUC_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HHQ8054204.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEEDGDVPS"
     gene            complement(1683..2006)
                     /gene="tnpB"
                     /locus_tag="ACSUUC_000976"
     CDS             complement(1683..2006)
                     /gene="tnpB"
                     /locus_tag="ACSUUC_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HHQ8054205.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWLSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
     gene            complement(1987..2172)
                     /locus_tag="ACSUUC_000977"
     CDS             complement(1987..2172)
                     /locus_tag="ACSUUC_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054206.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(2476..4038)
                     /gene="guaA"
                     /locus_tag="ACSUUC_000978"
     CDS             complement(2476..4038)
                     /gene="guaA"
                     /locus_tag="ACSUUC_000978"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HHQ8054207.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4180..4878
                     /locus_tag="ACSUUC_000979"
     CDS             4180..4878
                     /locus_tag="ACSUUC_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHQ8054208.1"
                     /translation="MLPAYMKIHDQIKKDIDEYRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4921..5817)
                     /locus_tag="ACSUUC_000980"
     CDS             complement(4921..5817)
                     /locus_tag="ACSUUC_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HHQ8054209.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5826..6761)
                     /locus_tag="ACSUUC_000981"
     CDS             complement(5826..6761)
                     /locus_tag="ACSUUC_000981"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HHQ8054210.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTASELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6758..7483)
                     /locus_tag="ACSUUC_000982"
     CDS             complement(6758..7483)
                     /locus_tag="ACSUUC_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HHQ8054211.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     SYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7567..8202)
                     /locus_tag="ACSUUC_000983"
     CDS             complement(7567..8202)
                     /locus_tag="ACSUUC_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HHQ8054212.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8204..9031)
                     /locus_tag="ACSUUC_000984"
     CDS             complement(8204..9031)
                     /locus_tag="ACSUUC_000984"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHQ8054213.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9053..10124)
                     /locus_tag="ACSUUC_000985"
                     /pseudo
     CDS             complement(9053..10124)
                     /locus_tag="ACSUUC_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241626.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10619..11230
                     /gene="def"
                     /locus_tag="ACSUUC_000986"
     CDS             10619..11230
                     /gene="def"
                     /locus_tag="ACSUUC_000986"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HHQ8054214.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11275..12003
                     /gene="rlmB"
                     /locus_tag="ACSUUC_000987"
     CDS             11275..12003
                     /gene="rlmB"
                     /locus_tag="ACSUUC_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HHQ8054215.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(12042..12953)
                     /gene="trxB"
                     /locus_tag="ACSUUC_000988"
     CDS             complement(12042..12953)
                     /gene="trxB"
                     /locus_tag="ACSUUC_000988"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HHQ8054216.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13019..13243)
                     /locus_tag="ACSUUC_000989"
     CDS             complement(13019..13243)
                     /locus_tag="ACSUUC_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HHQ8054217.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13321..14064)
                     /locus_tag="ACSUUC_000990"
     CDS             complement(13321..14064)
                     /locus_tag="ACSUUC_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054218.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14064..14864)
                     /locus_tag="ACSUUC_000991"
     CDS             complement(14064..14864)
                     /locus_tag="ACSUUC_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHQ8054219.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15022..15378)
                     /locus_tag="ACSUUC_000992"
     CDS             complement(15022..15378)
                     /locus_tag="ACSUUC_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HHQ8054220.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15391..15903)
                     /locus_tag="ACSUUC_000993"
     CDS             complement(15391..15903)
                     /locus_tag="ACSUUC_000993"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HHQ8054221.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGEPQDLSNLLLAPIGTNFEKRVWSYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNK"
     gene            complement(15903..16397)
                     /locus_tag="ACSUUC_000994"
     CDS             complement(15903..16397)
                     /locus_tag="ACSUUC_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HHQ8054222.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16532..16978
                     /locus_tag="ACSUUC_000995"
     CDS             16532..16978
                     /locus_tag="ACSUUC_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HHQ8054223.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16975..17622
                     /gene="trhA"
                     /locus_tag="ACSUUC_000996"
     CDS             16975..17622
                     /gene="trhA"
                     /locus_tag="ACSUUC_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAQR family membrane homeostasis protein TrhA"
                     /protein_id="HHQ8054224.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17643..18224)
                     /gene="pdxT"
                     /locus_tag="ACSUUC_000997"
     CDS             complement(17643..18224)
                     /gene="pdxT"
                     /locus_tag="ACSUUC_000997"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HHQ8054225.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREGILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18225..19100)
                     /gene="pdxS"
                     /locus_tag="ACSUUC_000998"
     CDS             complement(18225..19100)
                     /gene="pdxS"
                     /locus_tag="ACSUUC_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HHQ8054226.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19252..20631)
                     /gene="nox"
                     /locus_tag="ACSUUC_000999"
     CDS             complement(19252..20631)
                     /gene="nox"
                     /locus_tag="ACSUUC_000999"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HHQ8054227.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20925..21848
                     /locus_tag="ACSUUC_001000"
     CDS             20925..21848
                     /locus_tag="ACSUUC_001000"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HHQ8054228.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21908..22513
                     /locus_tag="ACSUUC_001001"
     CDS             21908..22513
                     /locus_tag="ACSUUC_001001"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase [NAD(P)H] activity
                     [Evidence IEA];
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HHQ8054229.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEETDGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22532..23776
                     /locus_tag="ACSUUC_001002"
     CDS             22532..23776
                     /locus_tag="ACSUUC_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HHQ8054230.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23893..24150)
                     /locus_tag="ACSUUC_001003"
     CDS             complement(23893..24150)
                     /locus_tag="ACSUUC_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HHQ8054231.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24192..26228)
                     /gene="glyS"
                     /locus_tag="ACSUUC_001004"
     CDS             complement(24192..26228)
                     /gene="glyS"
                     /locus_tag="ACSUUC_001004"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HHQ8054232.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26440..27357)
                     /gene="glyQ"
                     /locus_tag="ACSUUC_001005"
     CDS             complement(26440..27357)
                     /gene="glyQ"
                     /locus_tag="ACSUUC_001005"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HHQ8054233.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(27552..28313)
                     /locus_tag="ACSUUC_001006"
     CDS             complement(27552..28313)
                     /locus_tag="ACSUUC_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HHQ8054234.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDLNAATQIIRESAVPAYTNNRRMVMTPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVFDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28586..29428)
                     /locus_tag="ACSUUC_001007"
     CDS             complement(28586..29428)
                     /locus_tag="ACSUUC_001007"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HHQ8054235.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSITISRIQANLDCFGIELSHKERETLKTIAVQLGAPRVD
                     DVDF"
     gene            complement(29542..30933)
                     /gene="pgdA"
                     /locus_tag="ACSUUC_001008"
     CDS             complement(29542..30933)
                     /gene="pgdA"
                     /locus_tag="ACSUUC_001008"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HHQ8054236.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31171..31606)
                     /locus_tag="ACSUUC_001009"
                     /pseudo
     CDS             complement(31171..31606)
                     /locus_tag="ACSUUC_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            31760..32737
                     /locus_tag="ACSUUC_001010"
     CDS             31760..32737
                     /locus_tag="ACSUUC_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HHQ8054237.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            32734..33816
                     /locus_tag="ACSUUC_001011"
     CDS             32734..33816
                     /locus_tag="ACSUUC_001011"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HHQ8054238.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(33880..34664)
                     /locus_tag="ACSUUC_001012"
                     /pseudo
     CDS             complement(33880..34664)
                     /locus_tag="ACSUUC_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10246 a         7764 c         6234 g        10420 t
ORIGIN      
        1 agttcctaat ctggagattt cttatttgca cttttcttgt acaactttag tccacggtaa
       61 ataggcctct aaaacctctt tgtttacgag agtttcctcg tttggaagac attctagaag
      121 ataggataga tatttctcac tatttagttg atgacgttta gctgtttcca ataagctcat
      181 aataatagct cttgctttag ctccttcaaa aactttgaga aaacaaccac cctcgctttt
      241 ttaaactgag cttaggctaa aagagtccag tggactcttt tactccgtcc cataaccaat
      301 gatttaatgg cgcgttcagc tagattattg gaaaggacca gatgtccgtc ttttaaaatg
      361 gtcttaaagg tttcttcata cttgaggctg tattcaattg cccttcctag ttttgaaccc
      421 gataaaactg actgacgacg gcaccaagca aagaagtctt ctattagggg ttggagctct
      481 tcttgacgtt tctgtagtcg ttcatcagct ggcaaagcct cccagtctct ttccaaggaa
      541 aataactgat cacaataggc taatccttta gctcctaaag atgatttatc cgcttgcttg
      601 gggggcgctt caaaaaactt ccttctcaca tgtgcccaac atccaacaag ttcagcttct
      661 gccagttgac tgacgataag cttctagcgg ttcgcagttt accaagctta gcgtcgcctt
      721 gctcctaaac cttggactgc tatcgcatag gcagaactag aggactaaag tcctaagtta
      781 ctgccgcaac atgtcacaat gcacatagcc agaataatct cctaggaatt cttgtactac
      841 taaaccactc cgacgctgat catggtggta cagcgtgatt gcttgatttt cagctttccc
      901 agacaaaaag gtccaatagt aggtcagctg actatcactc tctagcaccc tataagaagt
      961 ttcatctgca tgaagtaagg gcttgagtca atagtctcgt tataaagggg ctttaggaat
     1021 aggagctttc acgattttat cactcggatt tttatcactg catgcttggc atttgtaagc
     1081 gtgttggata tgatctatgc gttttaattg cgcaggaata aagaccaatt cttgtccttg
     1141 aagactccct ccaatctctt ttagatctcc ctgacaatca gggcaaatcc tctcttctac
     1201 ttgatgatga acttcttctg aatcaaattg ggcaagaaga gcttggcgtt tccctttaga
     1261 tttcttacgt ttgtaggtaa tttcttctgt ttcaactggg aacatctcca tcttcctcag
     1321 atggagactc ttcctcaaaa aggttgagtt gtccagaggg gcaaacactt ttctcagagg
     1381 attttccata gagcttttga gtcagataag ccacttgttc acgcagaagg gcaagttcat
     1441 tggtgagact atcaattgta gcactctgtt gttgaatgat tttcaatctt cttccatgag
     1501 cttccctctc tgttttctaa ctttattata ctaaaaagaa agtcctcatt tcaatagaaa
     1561 tcacgacttt ctgatggatt tatagtaaaa tgaaataaga acaggacaaa tcgatcagga
     1621 caatcaaatc gatttctaac aatgttttag aagcagaggt gtactattct agtttcaatc
     1681 tactatattt ttggagtgat agaaaagccc ttcataagcc aatctacttg ttcaggtgcg
     1741 agagctttga catccttttc tgtacttagc caagtcagtt ttccgttctc aaagcgttta
     1801 tataatatcc aaaatccttg accatcccag taaaggactt taaagcggtc tttacgtcca
     1861 ccacaaaaga gaaagacttg atcggagaaa ggatccaatt caaagtgggt tttaaccaga
     1921 taagccagtg aatcgattcc ttgtctcata tccgttttcc cacatacgag atagacctgc
     1981 cctaggctag atagatgaat tgtcatagag caacacctta tccaaaagct gttctatcat
     2041 ttcgagattg agagattgaa aaaaacttac ttcaagcttg ccaatacgaa ttttaagcag
     2101 aatatcattt ctctttttag aatcaaaagg acgagattgt ggaatctcta caggaacaat
     2161 aggttgtggc attaaaatat cctccaatag ttttacttta ctaatagtat acaggaggag
     2221 ctccatgaat gatagatacc ttgttatgac gcgcttacta tattagaaag ttggctctct
     2281 aattaaatta attctcatta tatatatcaa aagaccgcag tttgaaaact acggtctaat
     2341 tttttgtcca aatgtaaacc acttggaact attattcaat ttattctttt tagcaaatgt
     2401 tcccgtttta atcccagtta cagtttttaa tcctctgtaa ccgttgattt tacaaagctt
     2461 ttaatttttt tgcgattatt cccactcaac tgttgcaggt ggtttacttg taatatcgta
     2521 gacgatacgg ttaacatgat ccacttcatt tacgatacgt actgagattt tttgaagtac
     2581 ttcccatgga attttggcaa aatcagcagt cataccatcg atagaagtga tagcacggat
     2641 tgcaatcgtg tagtcatacg tacgaccgtc acccataaca ccgactgaac gaacgcctgt
     2701 gttaacagtg aagtattgcc aaatatcgcg gtcaagtcca gctttagcga tttcttcacg
     2761 aagaatagcg tctgattcac gaacggtttc aagtttctct tcagtgattt cacccatgac
     2821 acggatagca agtcctggtc ctgggaatgg ttggcgccat acgatatggt ctggcatacc
     2881 aagctctgta ccaagagcac gaacttcatc cttgtaaaga gtattgagtg gttcaatcaa
     2941 ttcaaactgc atatcttctg gaagaccacc cacgttgtgg tgtgacttga tagtttgagc
     3001 tgtatccgta ccagactcga taacatctgt atataaagta ccttgagcaa ggaatttcac
     3061 atctttgagc ttgcttgctt cgtcatcgaa tacatagaca aactcgttac cgatgatttt
     3121 acgtttttgt tcaggatcag aaacgccagc aagtttgtca aggaaacgtt tagcagcgtc
     3181 tgctttgacg atattcaaac caaacttacc accgagcatg tccataactt gatcagcttc
     3241 gcctttacga agaagaccgt ggtctacgaa gatacagatc aattgatcgc caatcgcttt
     3301 ttggagaaga accccaacga cagatgagtc aacaccacct gatagaccaa gaaggacacg
     3361 tttatcaccg acggtttcac gaattttttt gatctgcatg tcaatgaaat tatccattga
     3421 ccagtcacct ttagccttac aaatgttaag ggcaaagtta cgaaggatat catttccgta
     3481 tacagaatga cgaacttctg ggtggaattg gataccgtaa atgtgtttat ctgggttttc
     3541 gatggctgcg tatgggcagt cagctgatgt acctgtacga acaaagtcag caggaatctc
     3601 agtaaccgca tcaccatggc tcatcaaaac agtctgttca tcaggtgttg attcaaaaag
     3661 cgctgatggt gtgtgagtta gggttgattg accgtattca cgatttccag catcacctgc
     3721 aggaacaact tttcctccaa gtttatgggt caataactgc ataccataac agattcccaa
     3781 aattggaatt ccgagttcga agatttctgg gtcaatatca aatgaaccat cttcatatac
     3841 agaatttgga ccacctgata gaataattcc tacaggattg acttcacgaa cttcagcagc
     3901 tgaaatttta tggcttttta gttctgaaaa aacaccaatc tcacggatac ggcgtgaaat
     3961 cagctggttg tactggctac catagtccaa tacgatgatt ttttctacat cttgcaaatc
     4021 agttgaaatg ttgctcatct ttttcctttc tcaaaagaaa tatcttttcc caatattcta
     4081 tcacaaataa gggcgaatta ccaactaaac aaggcgaagt ttgacttttt ctagtttatt
     4141 ggggtacaat agagaaaaga tagaaatgaa gtgaaaaata tgctacctgc ttatatgaaa
     4201 atccatgatc agataaaaaa ggatattgac gagtaccgtt gggctattgg tgagaggctt
     4261 cccagtgaaa gagatctagc tgagcagttt gcggtcagtc gcatgaccct ccgccaagcc
     4321 gtatctctat tagtcgaaga aggcgtctta gagcgccgtg taggaagcgg cacctttgtt
     4381 tccagtactc gagtacaaga aaagatgcga gggacaacca gttttactga aattgtcaaa
     4441 tcccaaggta aagttccctc tagccagctc atttcctaca aaaaaaccat tcccaatgag
     4501 caagaagttg ccaagctagg aatttttcca acggacaata ttatccgaat ggagcgggtc
     4561 cgctatgccg accaagttcc cctagtttat gaagttgctt ctattcctga aaaattcatt
     4621 aaggacttta aaaaagaaga aatcaccagt catttcttcc aaaccttgca aaaacatggc
     4681 tatcgtatcg gcaaatctca acagaccatc tatgctcgcc ttgctaaaga aaagattgcc
     4741 cactatttgg aagttgaaaa aggacatgct attcttggat tgacccaggt ttcctaccta
     4801 gaagatggta ctgcttttga atacgtaaaa agtcaatatg taggcgaacg ctttgaattt
     4861 tatcttgaaa ataattagat taccacgcaa aaactctctg tcacgaacaa agagtctttt
     4921 ttatttttct aagaataaat ctttcaaaga aatcaaagtt acagcaaaca atatcattgc
     4981 cataccaaga aaatcaatgg gataaaattg ttcattcatt attaagaagg caaagaaaat
     5041 cgccgatatt ggctcaattg aagccaacaa gcttgacttg accggtccta tcagactggc
     5101 tcctttaagg aaagctgtat aggcaaagac agtcccgata aggataatgc ctgcaaacgc
     5161 aaggagaaaa tcaagactag tcgggatatc ggcctgtaga acccctgtaa aaggaagggc
     5221 gaccaaacct gctatgacca ttcccacacc aatgaccaag ctgctccccc actttttaat
     5281 caaggctatg ggtaaaatga tatacagagc ataagtcaag gcagaaaaga gaccccagaa
     5341 cagaccagca ggtgtcatgg ataactggtc caactgccca tgtgttgcga tcaggaaggt
     5401 tcctccgatg gcgaatatga tggaaactat ctctcccagt gtcggtgcca ccctatcctt
     5461 gatacagcta taaattaaaa ttccgacagg acaaacatac tgaagcaccg tcgctgttcc
     5521 cgcattggtc tcctgaatag cagacagata ggcgaattgg ttgagaaaaa gaccaatcag
     5581 agcaaaaata agaagagaca gcaaactctt tctatccttt aaaaagacca gtattttatc
     5641 ctttgcagta gcataagcca agagcatgag aattccacca gcgattaaaa gacgcaagtt
     5701 agtcaagacc agagccgaaa ttccgtgtgc cattaggtat tggccactcg ttcctgacaa
     5761 cccccaagca ataccagcca caactgttag taaagtccct tttaaactat ttgacatgtc
     5821 tctccttact cttctttgcg aatcaagttc atcacttgat tgcggtctaa tatccattga
     5881 gctctctcgt ccttttcata ggtacgattc gataggaaaa tagtggcttc ttgcttctga
     5941 cgattccaca tgataaaggt acctgtatag cccgtatggt ctagccaatc tccttccaaa
     6001 ttccatgcta aagaacgttc cttgtcatcc aaaggagaaa aattttgatt taagtctctt
     6061 gcaaaatcat ctgctaaata gtgttctaaa aagatttgta aatcctttat agtcgaaaat
     6121 aaaccagcac tcccagcatg tctacccagg agacgagcct tgggatcatg cactatgcct
     6181 gcctctacac ctctaactgt tggaacagca agctcaactg gcccaaactt ggtttccgtc
     6241 attccccaag gtttccagac ttgatccttt aaaatcacat ccaaatcttg attaaaaatt
     6301 ctttccaaaa taaagcccaa cagcaaaaaa tggacatccg aataaagaaa ggctggctga
     6361 cttcgtctgt tgagatgaaa catcgcttcc tttaattcag aggctgttaa aagatcacga
     6421 ttaggaataa aaggatcaag gtctgttgca tgagtcaaga gctggcgaat agtgatgtct
     6481 ggataatcac tctcaggtaa aaaatctatt accagtctat caatatctaa ttgacctatt
     6541 tcccacaaga aggtacaaac tgtgccaacc ccaacaacct tgctgacact agctaggtca
     6601 taaactagtc ctgcctcagt ctgcaagcca tgctctgggg cactctggcc taaatagaac
     6661 tctgtccatt gattgtcctt aaaatacgca aaagaggctc cgggataaat tcctgcctcg
     6721 atttgttctt ctattttttt aataatcttg gtccacttca tacttcttca aaccacaatt
     6781 caacattatt tctatcttta ccaaggaaga atttttcaga cttaggaata aaatattcag
     6841 tagactcaaa cttctggcga agacttgcta tgtctaattc attgaccaag aacttgagca
     6901 tagataagtc ccaggtaacc gtattgtcca cagtcaaatc ctgcccctga gctggaataa
     6961 aatcaaggga tgccccaatt tcagatgatt ccaagaaact ttcgatatca gttgggagat
     7021 gtaattccat agaaatctca aatttactta aagaaattga tgccaaatct gtttgaaatt
     7081 caggcttttc tcctacttct actagacttg ctatgtcatc ttccgcatga atcaaaatca
     7141 aatcatcttc tggtgagaaa atttcaaaag cgtagctatt ttgaccttta tataatcgat
     7201 gaatcgaatc tgttttagat aagattcctt caatttctaa gggattttcc accttgacaa
     7261 tcaatctagc tagttttttt cttccctcta ccttacgagt acgcatactg ggagcttctt
     7321 ctaaaaccag cttttcaaga cccgtttggt cacctagtga cagaaaggcc gattcttcta
     7381 acaaggcctt cattccaagg gtttcaatat aaaatgtttc atttaatttt ctattattag
     7441 cttttaaagt aggaataatc cgtacaatct gatttacatt cataaattcc tccgtcactt
     7501 tttattttaa aggattttag aattttttac aagatattat gctcaaattt aacattattt
     7561 agctatttag taaagatagt ctttcaaggc ttttgacaaa gcctgataac cagcaatact
     7621 gaggtgcagt ccatcagttg tatattcttt tttgagttgg cctgcttggt ctgtcaaaca
     7681 atcaaatact ggcacaaatt ccacctgcat ataggcagat gcaagctctt gataggcttg
     7741 attccagttc tgaatttttt cattcgagcg gatatagact gcctgctggt actcctctct
     7801 ctcattgaca ggcaaaatgg aaagcaattt aatctctgtc aatggataat cgcgagcaac
     7861 ggattgaatg atagcttcga gattattgag agcctcattc acaggaacat cctttccgat
     7921 atcatttgtc ccaatcagaa gaaaaatttt atctactgct ccaccatata gatgagcatc
     7981 aaggttctct agtaacagtc ctgtctgata gccacgaatt cctcgattga caatcgtctt
     8041 tgaagtccca aatagctcct gtagaggata atactcgaca atggaatccc caataaaaag
     8101 aatgtttggt tctacaacag aaatgtgatt taggtgacga tacttagttt gaattttttc
     8161 ttgttccttt aggagccaat tttctaataa ctgtactgcc acttcattct cctttttcta
     8221 accagttttc caaaacttga taaactcctc cttggctgtt ggctggtgct agagcagtcg
     8281 ccacagcttt ggctttctca tcagcatttt ccatcgcata ggcaattcca gccatttcaa
     8341 gcatttcaac atcattttca ctatcaccaa aagccatgat ttcttgggat ttcaagtccc
     8401 agcgcttgag taattcctcc aagccccatg ctttatgaat cccagcttgg aggatatcaa
     8461 tgcaaccata gccactggat acagctcgga cacggccatc aaagagagca ttgatttctt
     8521 ccaaaaccga actcaaacgt tcctcaccaa caaccatgct catcttgagc acaccaccaa
     8581 agaggtcaga tgttaattca tccacaaatt gcatccgttg gtagaatttt tcaatcattt
     8641 ctggagtcat aaaactttca agatctgtaa aaatcgtacc ttccttgaca aaatcaccct
     8701 tcatccccgt tacaacaaac tggtcctgac acgctcgacc cttgaaatga gccaaagcct
     8761 tgttgacaat ggcgtcatcc catgtctgag cctgaatcaa ttcattgttt tcaaaaatac
     8821 gagcgccatt agcaacaacc agaaccactc gatccaccaa gggactcagt agttgtctca
     8881 tgcggtgaat ttcattgccc gtcgcaatga caaaacgaat gcccctttga tccaactgat
     8941 ctaaaatctt ttccaatcgt gggagatcaa gctgacccct agcatccagc aaggtcccat
     9001 ccatatctgt cgcaattacc ttaatcatca tttactttcc tctggattca agctaatacc
     9061 acttcaatcc cacatgttca ttcatttctt tataggctgt atcaattcgt tccttagtcg
     9121 cttcatctaa ctggtcacga tgactgccac ccctctataa aatcttccaa aatataagtt
     9181 tggtaatgat acaagggata tccttctggt gaaaaggttc cctttggtgt tcgattgacc
     9241 caagtaggat gagctttagc tgttccgata gttgtttttc catccttctt cttgatggtg
     9301 acatccatga gaacaccacg ttcagtccac ttagcattct cttcatctcc catagattca
     9361 attcgttgat tggaaatgaa gttccccatt taatagataa tgagtttctt atctccatct
     9421 ttttcaacca tttcagatgg ttcaacaacg tgaggatgcc ctccaaagat aatatccgct
     9481 ccccaatcga tcatcttgtg ataaagagct ttttgttctt cagttggttc caatcgatac
     9541 tcaacaccca tctgaagcat gataatggtg atatctgctt ccttctctgc ccgttcaatt
     9601 tcagccttca tcttatcttc gtttaaatct gaaagataac gattatagtc ttccttagaa
     9661 atatactgct caattccatt gaaaccatag gaataggcta acaatgcaac cttgatacca
     9721 ttcacttcct taatgaccag cggagcctga acacgtggtt cgtgcgtata aactccgatt
     9781 ggagtgattc cagctttctc aataatatcg gccgttgaaa taactccctc aatttgcgaa
     9841 tccaaaatat gattatgagc taaatccagc acatgataac ctgcctcctt aatagcatcc
     9901 ataacttcaa caggagcatt aaagagaaga taacccgcta aataatgatc cttattaatg
     9961 gttccttcaa aatcaccaat agctaaatct gcttgcttga gccaaggagt cacatactca
    10021 aaattttcat gaaagtcata ggtaccgtct tcttttttag ctgaaaagaa aagtccatcg
    10081 tggtagagca aatccccgtg ggccataatt ctggcagttt tttcctcttc ctactcctga
    10141 gacttttgct tagtcccctc ttgagaaata gtatctcgtt tttgactagt caagggattc
    10201 cttggaagct ttcaaacaac aagaccaagc ccattgataa accaactgct agcaagagta
    10261 tcgccacaaa tcccttattg ctccacttgc gataactcct aaaaagttta ccaagccctt
    10321 cataaaacga aaagctaaac caccctgatt tcgattttgt cttctttgta tcttcgttct
    10381 ccctactttc ttatgcaagc cttttctttt tattatatca cagataagta tttctttcac
    10441 aattgaattg aacttcctat ctattttcta taaatcctaa atgccataat gctttcaatt
    10501 cttgtcattt tgtgatatca tgtagaggaa atgaactaat ccacagtggc ttattccaag
    10561 tataccactt gggctttggc agtagctaac tgcactaaac ataatataag gagagaaaat
    10621 gtctgcaata gaacgtatta caaaagctgc tcacttaatt gatatgaacg atattatccg
    10681 tgaagggaat cctactctac gcacggttgc tgaggaagtc actttccccc tatctgacca
    10741 ggaaatcatc ctaggcgaaa agatgatgca attccttaaa cattcccaag atcctgtcat
    10801 ggctgaaaaa atgggactcc gcggtggtgt tggactggct gctccccagt tagatatctc
    10861 aaaacgcatt atcgctgttt tggtacctaa tattgttgaa gaaggcgaaa ctccacagga
    10921 agcctacgat ttggaagcca ttatgtacaa tccaaaaatc gtctctcact ctgttcaaga
    10981 tgctgctctt ggcgaaggag aaggttgcct gtctgttgac cgtaacgtgc ctggctatgt
    11041 tgttcgccat gcccgcgtta ctgttgacta ctttgacaaa gatggagaaa aacaccgtat
    11101 caaactcaaa ggctacaact ccattgttgt tcagcatgaa attgaccaca ttaacggtat
    11161 catgttttac gatcgcatca atgaaaaaga cccatttgca gttaaagatg gtttactgat
    11221 tcttgaataa agaaaatccc gttgcaagac ggggttttgt gttataatag aggcatgaaa
    11281 acaaatgata ttgtctatgg tgtccacgcc gttaccgaag ccctccttgc aaatacagga
    11341 aacaaactct acctccaaga agatctccga ggtaagaatg ttgagaaagt caaggaacta
    11401 gctacagaaa agaaggtgtc catttcttgg acatcaaaaa aatctctctc tgagatgact
    11461 gaaggtgctg ttcatcaagg ttttgttcta cgagtgtctg aatttgccta tagcgagcta
    11521 gattacatcc ttgcaaaaac acgccaagaa gaaaatccac ttctattgat tctagatggt
    11581 ctaactgatc cccataatct gggttctatc ttgcgaacag ccgatgcgac caatgtttca
    11641 ggtgtcatca ttcccaagca ccgtgctgtc ggagtaactc ctgtcgttgc caaaacagcc
    11701 acaggtgcta ttgaacacgt tccaattgcc cgagtgacaa acctcagtca aaccttagat
    11761 aaactcaagg atgaaggctt ctggaccttt ggaacggata tgaacggtac tccttgccac
    11821 aagtggaata caaaagggaa aatcgccctc atcatcggaa atgaaggaaa aggcatctct
    11881 agcaacatca aaaaacaggt cgatgaaatg attaccattc cgatgaatgg acatgttcaa
    11941 agcctcaatg ccagtgttgc tgcagccatt ctcatgtacg aagttttccg aaatagacta
    12001 taaaaaagtt tccagtcatc tgattggaaa cttttttatg attaactatg ttctgtgata
    12061 aacttgtagg cttcttgacc agcgatagct ccatctccaa ctgctgttgt tacttggcga
    12121 aggtctttca agcgaacatc tccaactgca aagataccgt cgactgcagt tttcatgtgg
    12181 ttatctgtca caatccatcc tgcctgatct tggatattca attctttaac aaaatcgcta
    12241 agagggtcca atccaacata gataaagaca ccaccgaagg cttgttctgt cacttgacct
    12301 gttttcacat tttcaaatac gactgattct actcggtttt cacccttgat tttccttact
    12361 acagaatccc atataaagct gattttctca ttggcaaagg cgcgatcttg taaaaccttt
    12421 tgggcacgaa gttggtcacg acggtgaaca atggtaacag tcttagcaaa acgagtcaag
    12481 aagagggctt cttcaacagc tgaatctcca ccaccaacta ccaataaatc ttggtcacgg
    12541 aagaaagcac catcacacac agcacagtaa gaaacaccac gactgttcag ttcttcttct
    12601 ccaggcactc ccaaaggacg gtgtttagaa ccagttgcta cgataactgt acgtgtttca
    12661 tatgtttggt catcagtcat cactttctta aaatcaccat ggtcttcgac attttcaaca
    12721 taaccataaa tgtgctccac accaagattt tcaagtggtt caaacatctt ttcagccaat
    12781 tcaggtccac taatattagc gtatcctggg taattttcga tatcagatgt attattcatc
    12841 tgaccacctg gcagaccacc ttcaatcaaa gctactttta gattgcttcg agcagcatac
    12901 aaggccgcag tcatccctgc aggtccagca ccgataataa tagtatcgta catatagatt
    12961 ccttctttct tgttgtaact atctttattc taactctttc ttgtcaatca cgcaaggatt
    13021 atgccttgaa aacaagaatt aaactcataa ccgcaaagga taatactggg acaaccaaga
    13081 ctccaatcat aatcatatca tagagatggg cttggcgagc cttggctgtc ttatcaactc
    13141 ccgacatggc tctcagacca atccaaatcc ctaaaaaaat cagaacaagg atggtggtca
    13201 atatcaaact ctcgaaatat aaagaaaata gttgcagtag catgatttct ctcatttcta
    13261 tcttttttaa agagtaaact cagctagtcc aactaactga gttttccttt atctattata
    13321 tcaaatataa gtccgtttgt aactagcgaa gaattctttt gtccgctctt ctttaggggt
    13381 gtggataatc tcatccggag ttccagactc gatgattttc cccttatcta agaagagaat
    13441 cttatccgca acttgggcta caaaggacat gtcatgactg accaaaatca tggtctgacc
    13501 tgacttagca gcatctgcaa tagacttttc tacttcaccg accaattctg ggtcaagggc
    13561 tgaagttggt tcgtctaaga gcaaaacatc tggtttcata gcaagcgcac gcgctagggc
    13621 aacccgttgc ttctgtccac ctgataaatg gcgaggataa tggttttcac ggtccgaaag
    13681 cccaacctta gccaactctt ccttggcaat cttagtcgct tcttggtcag ataatttctt
    13741 gacaacaacc aagccttctt tcacattatc aagtgctgtt cggcgttcaa acaaattaaa
    13801 ctgttggaaa accatagaca acttacggcg tagggcaagg atttcttctt gagtaatttt
    13861 agaaaaatca actgaaaaac catcaatctg aatagagcca ctgtcaggtg tttcaagata
    13921 attgagactg cgaagaaagg ttgattttcc agctcctgaa gaaccaatca aggctacaac
    13981 ttcccctttt tgaatatcca agtccagatg atccaagaca gtctgtcctg aaaaggattt
    14041 gcttaaattc gaaatcttaa tcattaacga aggtctcctt tcacatctgt ttgcactgta
    14101 tcaggtgcag aaatagccat ttttctctcg atgaaacgac cgaggctttc aattccgata
    14161 ttgactaccc aataaacaag ggcaacggag atgaagcgtt caaaatagcg ataatcagct
    14221 ccacctagaa tctgagcttg ggcaaagact tccacaacac ccgcactaaa agctagagat
    14281 gttcccttgg tcaaaccgat gagggaatta atcaaggttg gagtagctac caccgctgca
    14341 ttaggaataa tcactcgtcg ataaacttgc gctcgggtca tacccagact gcgtgccgcc
    14401 tcaatctcac caggattaac tgagagaatg gctgcacgaa tggtttcact agcataagct
    14461 gcctcattaa aggcaaaggc gacaatcgca aaagctgcag ctggaatcgc attgatattg
    14521 agaccagttc cccattgctg attgagggct ttcaaagcca aagggattcc gtagtaggtc
    14581 aacatgagtt gcaccaaaat cggtgtccct tttaagaaac taacaaagaa ggcctgcaag
    14641 ggatataaaa tcttgacacg attgatcttc acaatggcaa aaagaagcgc caaaaccaag
    14701 ccaaaaaggg caccaccaat tgtcaacata attgttgttg gaagttgttg gacaattcta
    14761 gggattccat caaagaccga acgtaggcta aacagcttgc catccggaat caattgcatc
    14821 aagttttggt accaatctga tgctaaaatc gttgtaacat tcataaaaac atcctcttct
    14881 gataatgatt cattctacca tgcttctgcc gtcaatgaaa ttatttgcta cggtcagata
    14941 cagactttgt ctacctacta gtttatcata ctttgaaaca gggaagttat atattttatc
    15001 tatcaaagag atagataaaa actatttcag tcccagttct tcataagatt ttcgataacc
    15061 gatttgctta acagttccat tttctactaa aatgggccgt tttaacaaca taccgtcact
    15121 tgctaacaac tcagccgctt cttggtttga caaacttcct accttatctt ttagccctaa
    15181 ttcacggtat ttgattccac tggtgttgaa aaattgcttc aattcaaatc ctgaggtttc
    15241 tagccaattc aaaatgactt cttggctagg tgtttcttcc acgatatgga cggctttata
    15301 gtccacacct aattgattta attcttgttt tgctttttta caagttgaac atttggggta
    15361 ttcgataaat tctaacatgt gcttctcctt ctatttgttt ctatctttaa aatctactcc
    15421 ttcatgctcc aagagccaag ctttcttttc cactcctgca gcatagcctg tcagacgctt
    15481 gcctgctccc aacacacgat gacaaggtac taggatagac caaggattgc gtcccactgc
    15541 tccaccaatt gcttgagcag aagccacttg caggtcttga gcaatttgtc cataggtcac
    15601 tgtctgacca taaggaattc cctgtaaata ggaccaaact ctcttttcaa aattcgttcc
    15661 aattggcgcc aagagcaagt tggataaatc ctgaggctcg cctttaaagt aatcatctaa
    15721 gcaagcaata actgggtcta aaataggatg actaacaact tcttctatcg tttcatctcc
    15781 tagtcccctc tcaaaatgct tctgctcctg aacccaaatt ccatacaaat aatggtcatc
    15841 agctacaagt gatagaatac caattggtga ggagtagagg atttttacat acttcttttg
    15901 cattatttct ttaatttttg ataggccaag cgttcgccat ctactggcac cttaccaact
    15961 tgtttaaaac caagtttttc aaaaatatgt tgcataacct tgttttcagc atgcgtatct
    16021 gagcgaaaat caagataatc aaaaccttca atcaagccct ctaagaaggt ttgagcaact
    16081 ccttttccct gcacatctgc tgccacagca atacggtgaa agactagata ctctgactct
    16141 ccagcttgcc agtttccctc ataaatagct tcataggcct cctctggact cttggtcaca
    16201 gcagcatagg ctagcagttc tccctcttcc aaggctacgt aggcttgccc tgagatgata
    16261 tcatcgataa taacatctgc atttggatag ccattttgcc actggttact accagcatct
    16321 gctaaacatt ttttggcatc ctctatcacc tgcatgatgg catctacttc atttggaaaa
    16381 gctaaacgaa tttccatctt ttttcctcat ttctgactag tttctcccat catagcataa
    16441 tttaagtctt tctacaagca gttaaaactt gactttgtat ttttgttatt ttataatcta
    16501 gttatcaaaa ctatataaaa aggagttgaa aatgaaaact accttttcct acccaaaatg
    16561 ggcagaaatt ccaaacatta acctctatct ggaccaggtt ttgctctatg tcaatcaggt
    16621 ctgcgcccct atctctccta ataaagacaa aggcctaaca gcatctatgg tcaacaatta
    16681 tgtgaaaaat ggttacctga caaagcctga caaaaaaaaa taccaacgcc aacagattgc
    16741 ccgtttgatt gctatcacaa ccctcaagtc tgtattttct attcaagaaa tagcccagac
    16801 acttaatact ctacaaactc aagcaagttc agaccaactc tacgatgctt ttgtggacta
    16861 catgaaccaa ggaattgacc cagctaaccc tattatccaa accagctgcc aaaccgttaa
    16921 actctatcat caaactctag acttaatcga tcatactcaa gaggaggtaa tccaatgaac
    16981 actagtctta aactcagcaa acaactcagt tttggagagg agattgctaa tagcgtgacc
    17041 catgctgtgg gtgcagtcat catgcttatc ttgctgccta tttcatccat ctatagttat
    17101 gaagcacacg gatttttatc ctctatcggc gtttccattt tcgtcatcag tctctttctc
    17161 atgttcctat catccaccat ttatcactct atggcctatg gttcgaccca caaatatgtt
    17221 ttgcgaatca ttgaccattc tatgatttac gttgccattg ccggctcata cacgcccgtt
    17281 gtcttgacct tgatgaataa ctggtttggc tatctgatta ttgtcatcca atggggaacg
    17341 accatctttg gtattctcta taaaatcttt gctaaaaagg tcaatgagaa atttagcctt
    17401 gctctttacc tgattatggg ctggttggtt ctggctatca ttcctgccat tatcagtcaa
    17461 acgacacccg ttttctggag tctcatggta actggcggac tctgttatac agttggagct
    17521 ggattttatg ccaagaaaaa accttatttc cacatgattt ggcatctctt tatcctagct
    17581 gcgtccgcac ttcaatacat cgctattgtt tattacatgt aaaaaagttg agaaattcaa
    17641 tctcaacttt tttctttaca catattgata aagtactggt gcaagcgcac atcatcagtc
    17701 aattctggat gaaaagaact taccaacata tttttttctt gggctgcaac aatttgattg
    17761 ttcactgttg ctagaatttc tacaccctca ccaacactac tgataatcgg accacggata
    17821 aaggtcattg gaatcttgcc aactccctta cattctgctt ccgtgtagaa acttcctaat
    17881 tggcgcccat aagcattacg ctcgaccacc atatccatag ttcctagatg actctctttc
    17941 tgagaagtga tttccttagc cagcaaaatt aagcccgcac aggtcccaaa cactggtaag
    18001 ccagatagaa tgccttctcg gatgggaagt agcatgttct ggtcacgtaa gagcttgccc
    18061 atggttgtag actcaccacc aggcaaaatc aaacccgaca agtcactctg atcttgctga
    18121 aaatcatcta gatttctgag ttctacactc tcgacaccta attgatctag cacttttgca
    18181 tgttctgcaa aggccccttg caaggccaat attccgattt tcatctattt tcctcgttca
    18241 gccatgagaa tttggatttc attttcatta ataccaacca tggcttctcc taaatcttca
    18301 gagatttgag ctaggatttg aggattacgg aagttagtca cagccttaac aatggcactc
    18361 gctcgtttaa caggatctcc tgacttgaaa atacctgaac cgacaaagac cccctctgcc
    18421 cctaattgca tcattaacgc agcatctgct ggcgttgcaa cacctccagc agcgaaattt
    18481 acaactggca attttccatg ttcatgaaca tattggacca attctacagg gacttgcaaa
    18541 tccttggcag caacataaag ctcgtcctca cgtaagtttt gaatgcggcg aatttcctga
    18601 ttcatcatac gcatatgacg aacagcttgg acgatatccc ctgtccctgg ttctcctttg
    18661 gtacgaatca tggaagcacc ttcagcgata cgacgcaagg cttcacccaa atccttagca
    18721 ccacagacaa aaggaacttg gaattctttc ttgtccacat ggaaacggtc atcagctgga
    18781 gatagaactt cactctcgtc gatataatca atttcaatag cctctaaaat ctgagcttca
    18841 acaaaatgcc cgattctgac cttagccatt actggaatac taaccgcttc ttggatttcc
    18901 ttaatcatct ttgggtcgct catgcgggaa actcctccag ctgcacgaat atcagccgga
    18961 attcgttcca aggccatcac agctgccgca ccagcagctt ctgcgatacg agcctgttca
    19021 ggattctgca catccataat aacaccaccc ttgagcatct gtgccaagtt tttatttagt
    19081 tcataacgat tttcagtcat ttgttttatc ctcatcattt gtattggtag ctaccttttc
    19141 attttaagtc agaacagaat gaagcacaag ataaaaaaac tataattgta tggggacaga
    19201 ttagctaaaa actatctgac cttaacttaa ggccagatag ctcattcatt tttatttttc
    19261 agccgtaagg gcagccattg tgatgtagtt gtatggtttg ttgaagtgtg gcaagaagaa
    19321 gaggtctgtc aatgccaatt tatcaattgt cacatgctct tggatagcaa gtgagaacat
    19381 gtggattccc atgctaattg caatatcatg tgaaaccatt tgggcaccaa gaatttcacg
    19441 gctatctttg tcaaagacaa tcttaattgc tacttcatgg ttgtcatgtt tcatgaattc
    19501 tggtttttga agatcgttaa agcctgtttc agttgcgttg taaccagcag ctttcgcttt
    19561 ttcaagagtc aaaccagttg aaaccatgtg aagaccgtag attgagatac catttgaacc
    19621 ttgaacaccg attccttcca attcatgtcc acaagcgttg taggcaccaa cgataccagt
    19681 gcgaacagca tttgaagcaa gagcgatata gcttgtatct ttacgagcat tgtcataaac
    19741 agtcgcacag tcaccaacag cgtaaacgcc tgggatagat gtttcttgtt tcttgtctac
    19801 aaggaaggca ccgttgcgga agagttcgat cttaccatct gcaagggctg tgtttggacg
    19861 gaaaccaact gcaaggataa ccatatccac gtcaaagctt tctttgtcag taatcaagcg
    19921 ttcaacttta ccgtcacctt cgattgcttt aacagtttga cctagagcca agcggatgtt
    19981 gtgatcttcc aagttcttcg ccatcatttg tgtgaagtct ttgtcatagt aaccgttcaa
    20041 gacagtatca acgatatcaa caaggacaac ttcttttcca agacgttcaa aggcttcagc
    20101 aagttcaaca ccgatgtaac caccaccaac aacggcgata cggtcgaggt gttggctctt
    20161 gtcagaaagt ttattgataa cttcttcagc attttggtac aatttcacga attgtacgtt
    20221 ttcaagagtt gctttaaatt cgcggtttcc tttaacaatt tcaacacctt cgattggtgg
    20281 caagattggt gtagaacctg tagcgaaaat caatttttcg tatgattctt tgtgctcttt
    20341 tccttcaact tccgctgtaa ctactttgtt atcatagtcg attgaaagaa caggtgagtt
    20401 catgtaaact ttagcacctt tagcttccaa tttttcttta tcagaataga acaagccttc
    20461 agcaccgtca atttgttcac caatccaaag agccattcca catcctagga aagagatgtt
    20521 agagttttgg tcaaatacaa caatttcgtt ctcatttcca aaattatcca acatggtatt
    20581 gatacatgct gtaccagcgt ggttagcacc gactacaacg attttactca taaaaatttc
    20641 ctgccttcat tctaaattta ccttactagt ataccattta ccgttagcgt ttacaagggg
    20701 ggtactatta tttcagcatt ttttatcaaa aataattccc catttatcct gttttcaagc
    20761 ctcatgaatt ttatgagcat atttcttgac tttttccaaa ttttgtttgt gaaaattcta
    20821 actttatggt attataataa catgaaaatg aaatgtaagg gcttcaattt agatgattat
    20881 ttgatattac aacttatttt ctataagaga aaggagttgg tagcttgact cttcgttcac
    20941 attctgaacg gctaatgggg actactatca ctatttcatt agtggatgag caagccgata
    21001 tctttctcca aaaatccttt gacttgctca aagaacttga ataccgcttc aacgccaata
    21061 gtcaagaatc tgagttgatg gaaatcaatt atcaagcagg aatagccccc gtcacggttc
    21121 atccagacct gtttgagctg atttcacttg ggttagagca tagcctagcg ctctctagcc
    21181 acctcaatat cagcattggt cccttaattc aaacctggcg tatcggtttt tcagatgcca
    21241 aggtcgccca gcctcaagaa attgaatcgg tgctgcctct aatcaatcct catggtatcg
    21301 agttagattc ttctacttct actgtgtttt taaaacagaa aggaatgaag atcgatctag
    21361 gttgtttagc caaaggatac agtgcggata aggttgccca atttcttagg aaagaggggg
    21421 tgacttctgc cttgatcaat ctgggaggga atatcctgac cattggaaaa aatcaggcaa
    21481 gaggggataa cccatggcaa atcgggattc aagacccagc caatcctagg ggaaatcatt
    21541 taatgaccat ccctgttgtc aataaatctg tcgtgacttc aggcatttat gaacgtcacc
    21601 tgaccgtcga tggacaagat taccatcaca tttttgacag tcaaacagga tatcctgttg
    21661 aaacggaact agcgagtcta acaatcatct ctgataaatc agtcgatggc gaaatctgga
    21721 cgactcgact ctttggagaa agacctgctt ctatcctctg gcaagtcgaa agtttggagg
    21781 gcatcgaagt catcctcatc gataaagaag gccacctaag ctgttcttca ggaattccta
    21841 ctctatagag acaactgttt caatggaatt ttaaaattgt attatgtaaa aagagaaagg
    21901 aaatctcatg ttaaaactta ttgctattgt tggaacaaat tcaaaacgtt ctacaaaccg
    21961 tcaattgctt caatacatgc aaaaacactt tgctgacaaa gctgaaattg agcttgttga
    22021 aatcaaggcc attcctgtct tcaacaaacc agctgacaag caagtacctg ctgaaatatt
    22081 ggaaattgct gctaaaatcg aagagacaga tggcgttatt atcggtactc ctgagtatga
    22141 tcactctatt ccagctgttt tgatgagcgc tcttgcttgg ttgtcttatg gtatttaccc
    22201 acttttgaac aaaccaatca tgattacagg tgcttcttac ggtacgcttg gttcatctcg
    22261 tgcccaattg caacttcgtc aaatcttgaa tgctcctgaa atcaaggcaa atgttcttcc
    22321 agatgaattc ttgctctcac actctcttca agcatttaac ccaagtggcg acttggttga
    22381 ccttgatgtt atcaagaaat tggatgccat ctttgatgac ttccgtatct ttgtaaaaat
    22441 cacagaaaaa ttacgtaatg cacaagaatt acttcgcaaa gatgctgaag actttgactg
    22501 ggaaaatttg taagatagga gaccaaaaag aatgaaattt gttggacttg ttggatcaaa
    22561 ctacgatcaa tcatataacc gtaagctctt ggaatttatc cgtcgctact tcaaactcaa
    22621 atttgaatta gaagttcttg aaattgacga agttccaatg tttaaccaag atgaaaaatg
    22681 ggatgaaagt ttccaattac gttatttata taacaaaatt actcgtgcag atggtgttat
    22741 cattgctact cctgagcata accacactat ctcagcttca ctcaaatctg tacttgaatg
    22801 gctttcatac gaagttcatc catttgaaaa caagcctgtt atgattgtgg gtgcatcata
    22861 ctatgaccaa ggaacatcac gtgctcaagt tcaccttcgt aaaatccttg atgctccagg
    22921 tgttaatgcc tacacgcttc caggtaacga attccttctt ggtaaagcta aggaagcttt
    22981 tgataacaac ggaaatatca ccaacgaagg cactgttaaa ttccttgaaa cttgcttaga
    23041 taactttgtt aaatacgtag gagtcgtttc gaaattgaaa aaaccaaaac caatcgaatc
    23101 agaagacttg gattgtggaa aaccaatcgc tacaaccatc acagaagttg accctgacga
    23161 tccagaatgg gtagaaaaag ttgcagcaat cactggtgct gtttctggtg atacctatgt
    23221 caaattggac cacggtatcc taacagttaa ccaaattgat atgttcttga aagctatgcc
    23281 atttgaattg acatacgctg acgataacaa ccaattcctc tactacaaca acgctcacca
    23341 agatccagac actatgttcg ctaaacgtgt accacctcaa tcaggtagcc gtatgtcgac
    23401 tgttcatggt tctcttccac cagcacgtat gaagaacgta gagtgggtta tcggaacact
    23461 tcgcaacgga aaccaagaat acgtccgtac gatcgttcca ggttctcctg caggtgttat
    23521 caacactcac aactaccaag caatgtacta tcctgatgga tcatacgctg gtatcaatga
    23581 aatcgtcttt aacttccaac catggcttga ctggtaccta aaagagactg gtcaacgttt
    23641 ggtgggtggt agcggaccat ttgctcctgc tgccggaggt catggagacg ccgatgctac
    23701 ttctggcgct tctgattcag gggatgctgg aggccacggt ggtgacgcag acgctacagc
    23761 cggtgcaagt tactaatgat agtttttagg aaccattatg gttccttttt tagcgaaaaa
    23821 agactagcaa acacaaactg ctagtctctt tgttatcgtt tcatctatct ttgttaaaag
    23881 aaagaataca tattatgaat ttggatcatc aagactacgg ccatgtaatc ctttttcacg
    23941 ttgtacttgg cgtagttttt ctggtgtaac atcgtttcct tcttcgtcca caattttgat
    24001 tccttcaatg tggtgacgaa cagcgcggcg ataaccttcg atgtactcct cacgtagttt
    24061 ggcttgttcc actttttctt ctggtgttaa gccttctgtt tttttctttt tagcaagctc
    24121 attgatacga gcaatttttt tcggatccat ttcttctcct ctgtaataag ataaagtccg
    24181 tttatcaaat tttatttagt gttaatttgg ttaaaacaag caaacttagc tgctttcttg
    24241 gttagttgtg acaagattgc caaacgattt tgacggacag cctgatcttc agccattacc
    24301 atagtatttt caaagaaagc atcaatgact gggctaagcg caaagagttg tttcaattgc
    24361 tgacttgcag gtcctgataa aacgagtgtt tctactgctt ctgccaaagc tttttcttgg
    24421 tcattctcaa atagtgctga atcaaccgta gcaacccctt ctgccttctc agccaggtta
    24481 aaggcacgag aaagtgattc aacagatggt ttaaaatctt cttccttgct tacttctacg
    24541 agagcacttg ctgcttccaa catatctgcc acaacaaagt ttgaacctgc aagaactgct
    24601 tctttgatat cttttggagt agagcccatc atcttatcaa cacgagcctt gataaagtcc
    24661 ataacctctg ctttattttc ataagtcaaa ctgtcaaatt tcaatgcata aaggctatca
    24721 atcagctcat ccatagcaat gtgccaacca aaggcatcca agatacgaac cacaccttga
    24781 gttgcacgac gaagggcata agggtcatta gaacctgatg gaatcaatcc tactgagaag
    24841 aaactcaaaa tcgtatccaa tttgtctgca atggctagaa ctgcgccgac cttgctctct
    24901 ggaagttctc cttcagctga tgtaggcatg tagtgttcac gaatagcagc tgccaccgct
    24961 ggagtttcac cagcaagaag ggtgtatttt tcacccataa ttccttggag ttcgtcaaat
    25021 tcaccaacca tacctgtcaa caagtcaaac ttgtaaatgg ctgctgcacg agcaaggtca
    25081 actgtttcat ccactgacaa accagctttt tctgccaaaa gtacagtgat ttgacccgta
    25141 cgaatcatgt gttcacgaag ggaaccaatc ttctcatgga aggtgacatt gtttaatttt
    25201 tcaacaagat ctgaaatcac caatttttgg tcttcacgcc agaagaattc tccgtcttcc
    25261 aagcgggcta ccaagacttt ttcatttcct ttgatgacat ttttcaaacg ctctgcgttt
    25321 ccgttacgaa cagaaatgaa gtttggcaag agttttccat cttgatcacg aacaacaaag
    25381 taacgctggt gttccttcat agaagtcacc aagacttctt ctggaacttc aaggtattta
    25441 gcatcaaaac ttcccatgaa ggcagttggg tattcaacca aattcaagac ttcattcagc
    25501 aaatccgcat caatttcgat acgtacacca tgttttgcct caatttcctt gatttggtca
    25561 acaatcattt gctcacgttc acatggatct gcgattacaa actgcttacg aaggtcttct
    25621 tcatagctca atgctgactg aattttggtt tctttcccca agaaacgatg gccacggctc
    25681 acacgacttc ccttgatatc aaggaaatcc aagtcaaact cttgctcatc caagagaaca
    25741 gttaaagtgt ggacagggcg gatgtattca aagctatttc cagcccagtg catgctgaca
    25801 gggaaagtca atgacttcaa gacatctaca acaccaggaa caatggcttc aactgcttga
    25861 ccaacttctt ccttagtgac atagacatat tcttcaccct tgatttcacg gaattcgata
    25921 tcttcaacag tcaagccttt tccacggaca aatccttgag ctgctttggt gaagtttcca
    25981 tcactatcca aggcaatttt ctttgctggt cccttgaaat cttctgtcaa atcagactgt
    26041 ttgtctgata aaccagtcac acgaacagcc aaacgacgtg gtgttgagaa ggtttgaatg
    26101 gcttcaaaag acaggcggtt ttccttgagg aaggctgcca ttttttcgcc tagttgtttt
    26161 tcacttggtg tgacaacata ggctggtaat tcttcaagac cgagttctac taataagttt
    26221 tttgtcatgt tttttctccg aaaagtatct ttttattttc cagtttgcct tatgtgattg
    26281 gcacgcaagc aaccaacttc gttgtttcat tgctaaaatt ggagccaaaa gtctccaatt
    26341 ttgcctagta tccttagttt cactaaggat accttcatca ctgcggcaac tggctcaggg
    26401 ctcactctgt tcgcccattt tcgtaatttg tcactctctt tattctgcgt cttctgctaa
    26461 aagtttaact cgtgtttctt catccaaaag tgggtaacct aggcgtttgc gttctgcaac
    26521 aaaggttttg gctacaacac gggccaagtt acggatacga gcgatatagc ctgcacgctc
    26581 tgttacagat acggcaccac gcgcgtcaag cagattaaag gtatgtgaac atttgagaac
    26641 atagtcatag gcagggtgta ccaagccttc ttctaatgca cgaccagctt ctttttcaaa
    26701 cttatcaaag ttttcaagca acatttcttg gtccgaaatt tcaaatgaat attttgagtg
    26761 ctcatactca ggctggataa agatttctcc gtattttaca ccatcagccc actcgatatc
    26821 atagacagag tctacttctt gaatgtaaga agccaagcgc tccaaaccat aggtaacttc
    26881 cgcagtcaca gggccagttg ccaatccacc gacttgttgg aaataagtga actgagtgat
    26941 ttccattccg tcaagccaaa cttcccaacc aagaccagct gaaccagttg atgggttttc
    27001 ccagttgtcc tcaacaaaac gaatatcgtg ctccaaagga ttgattccca atttttccaa
    27061 agactcaagg taaagttctt ggatatttga tggagaaggc ttcatgacca cctggaattg
    27121 gtggtgttgg tagagacggt tagggttttc cccataacga ccgtcagcag gacgacgtga
    27181 tggctctaca taagctgcat tccatggctc aggtccgata gcacgaagga aagtgtaagg
    27241 actcattgtt cccgcacctt tttcattatc ataagcctgc ataagcatac aaccttggtc
    27301 attccaaaat tgttgcaaag tcaaaataat ttcttgaaat gttaatttct tagacattga
    27361 atactcctta ataaaaaata attacttgcg acacgagtct gcctcgtcga tcatacgagg
    27421 caagacgagt tagtactgcg tctagctcag gcactctagt gctgagcgtg gggcagtccg
    27481 actgtaagga ggtttctgcc actgatgcag tgaaatgtta atttctcaga cattgaatac
    27541 tcctttagtt tttatatttc tttttcaatt aatttctgct gaacaaacca atctaacaag
    27601 ggaaaagttt tttctgtatt tgcccataaa tgataagaat caaagaccgc ttgtacacta
    27661 cctaaatttt ctaccaactt atctactgtc aaaaagctgc gccagtattc ataaaaaata
    27721 cttgcatagt tcttatcata agtcgaagaa ccaaaatcat tcaatgaatg ccaaccatac
    27781 ttcttctgaa aaagttctac gagagattga ttacaaattt tttccgcttg aaattcctct
    27841 tctgtcaaga aatacttgcg actaatatat tcaaccatcc cctcttcgaa ccagatataa
    27901 gagtcataac catcaaaatc atctaaaaaa tgctccgacc aatgagctaa ctcatgtcct
    27961 acaatctgta agaggaaatt ttcagataaa gaatgatagt ggctttctat tgcttgagtt
    28021 tgctcagaac actcgtagtc catcaactga tacaaataca actctttcca aacagctaaa
    28081 tcaggcgtca taaccattcg tctattattt gtataggctg gaacagcact ttccctaata
    28141 atctgtgtag cagcattaag atctgaccaa ataacggctt gcggtaaatc acagactgca
    28201 agttcattct ttaaaaaaga ttgataatct ttcaactttt cagtatttct tactacaaaa
    28261 tcacgaaatg tagctagttg actatcgtct tttacaagat aaaggttgtc cacggctctc
    28321 ctttctttca cacaatagac tgaataagca aaagaaccac atctgacaag cctaggttga
    28381 tttaacctag gggcgtcaga aacgcggttc caccctaatt tattacttca ttgtttttga
    28441 aaatactaca gaaagcgcca gcccattatt ttgccctact tggctcccac tgtcccaagc
    28501 tcgcttgaag aacgccataa gactttcttt cctgctgact attatatcaa aaattagaat
    28561 aatgtacaat tctttttatg attttctaga aatccacatc atcaactcgt ggagcaccca
    28621 attgaacagc aatcgttttt aaggtttctc tctccttatg actcagttca attccaaagc
    28681 aatcaagatt agcctgaata cgagagattg tgatagattt tggaagtggt aaaaatcctt
    28741 ctgccaagct ccaggccaag gctatctgag caaccgattt tccgtgattt gctgctattt
    28801 cttggacttg cttgctatca aacagttctc cttgtccaaa aggcccccaa gcttccaata
    28861 aaattccctt ttcacgacag taagctacga cttgatcttg atacacacct ggcgccaagc
    28921 gaacttgatt gaccgcagga acgatagttg cagtttcaag caaggcatcc aaatgatggg
    28981 gaagaaaatt gctaacgccg atagcacgga ttttcccttc ttgatagagg tcttccatcg
    29041 ctctccaaac ttccgcattg cgagttttcc atgcgtcatt ttctctgagc ggttttgggt
    29101 tcggccaatg aatcaaatac aaatccaaat aatccaagcc cagtttttct atagattttt
    29161 ccaaagcttg acgagtttgc tcataggttt gctgactatt ccaaagcttg gtagttacga
    29221 acatttcttc acgtggaact ccgctatctt tgattgcttg accaacactt tcttcattct
    29281 gataaatcgc cgccgtatca atatgacgat aaccagcctt caaggcttct aacactgcac
    29341 gataggcttc ttctccatcc ttagccttaa aagttccaaa tcccaatact ggaatttcta
    29401 ctccattatt taattgatag gtattcatat gcttctcctt ctattttatt catcaattat
    29461 agcataaaac attttttaag tagtactatc ttctgtaaaa aataagtctg tcaaatatct
    29521 aacagaccta ttttttcttg cttattcatc acgactatag tacagctcat gagcttttag
    29581 gcgagtattg agcatctctg gtatggtcac aaaggtataa ccttgatttt tcaaatactc
    29641 aatgaccctt ggcaaggcat tgactgtcgg actgtgaata tcatgcatca aaacgataga
    29701 gccgttagct acttgatgct gaatttctgt caaaatagat gcttcatttt tactcttcca
    29761 gtccagacta tccacatccc acatgataaa gctcaaatcc aagctattgc gaatatcatc
    29821 tgtaatagca ccataaggtg gacgcatgag tttagaacta gaacccagca ctttagttag
    29881 cacatcctca gtatcagtaa tctgcttttt agcttcatca agagagagtt gcgagagaat
    29941 cggatggctc caactatggt ttccaacaac atgaccttca gattttatcc tcttcaccaa
    30001 gtcctcattc ccagaaacat ttttcccaag cacaaagaaa gtcgctttaa tatcatattt
    30061 agctagggtc tctaatacct gcggggtcgt tgctggattt ggaccatcat caaaggttag
    30121 agcgacaact ttttgatgtt tcttatcaaa gtaagattgg tacaaggccg catctttttc
    30181 gagtaagtac gaagattgga taacatcaaa gaaagcagat actggcaagg ctatctcttc
    30241 taaattttca accacaggac ttggataaag gataatctga ctatccttgt aatcaaaatt
    30301 ccatgcagac aagtcttggt cagagaagtt ttttacaatc tgctcactct ggtcttgctc
    30361 tattttttta tcctctatga aggaggtcaa ctcttttatc agctgttcct tagccttact
    30421 agcatctgaa aacagttggt caagtgtaaa aggttgccca tcttctgtta agtgaacctt
    30481 tcctagactg gtcttttcag tctcttcaat cttaaaagca actaaatcat agatttgttt
    30541 ggtcacatta cgattaacga ctccctttaa acctgactct tcttgctctg tatagtagaa
    30601 aacaagattg tccttacttt ctagcttgtc cttaacatct tgatttatca gctccctaac
    30661 agaggaaatc actttctccc cttggagagg ataataggca atcacttcgg cttgcccctg
    30721 acgaaaatgc tccttctgat ttccctcact caattgatca tctttctctt ttttgagcga
    30781 ttcaatcttt tgctcaaaac ttttttgctg gtagatctta aaagcaataa atccgcctaa
    30841 taggcaaata gaaattgcta aaataccaat caaagccaat aatacatgtc tcgttttccc
    30901 gtgtctgcca cgtcctagtc tacttttatt catatttata tcataacaaa tttgagcaat
    30961 aatttcaatg atacaatttg gcaatccaca attcctctag caagccaaag catcttacat
    31021 caactccaac atccgtatct gtagagatta tgtagttttc tatctatgga atttctagta
    31081 gattgaagct agaatagtag acctatactt ctaaaacatt gttagaaatc gatttgactg
    31141 tcctgatcga tttgtcctgt tctcatttca tttcactata aaactatgaa aagctaggtc
    31201 atctgagaag taattactat cgacaattgc gatagcgtat actagtgcga tttgtttgta
    31261 gctctggtgg gtatcacctt cacgttggcg aattttttct aggttttgat taacctgact
    31321 gcacagataa gcccataggc gattgatgaa aaaattctga tgatgaacct gaatttcgat
    31381 gataacttgg attccattat ctaactccgc caagacgtct atactagtat agaaatcttg
    31441 cgctgagtag ggcatggaag gcaagacgtg aatgttactt ccctccaaaa tcgtcacatt
    31501 ttttgctggc aagtccagca tatcgcggat aaattgacaa atcattagtt gggctgatac
    31561 ctggatgtct gagaatcctc cttttcctcc ttctattata gcacattttt aaatctaggt
    31621 ttgctagatt ctatgcttct atctatttat tcggaaaaga aagctaatag cttatttgaa
    31681 attttctcct ctctgttgga tagtcccgtc tatctatgtt ataatgaaag aaggatttaa
    31741 aatcggaaaa ggagtattta tgctaaaatt aggtgtcatc ggaactggcg ctatcagcca
    31801 tcatttcata gaagcagccc ataccagtgg agaataccaa ctggtcgcaa tctattctag
    31861 aaaactagaa actgcagcaa cctttgcttc tcgctatcag aatatccaac tattcgatca
    31921 attagaagtc ttcttcaaat cttcttttga tttagtctat atcgccagtc caaactcctt
    31981 acattttgct caggcaaaag ctgccttgtc tgctggtaaa catgttattc ttgaaaagcc
    32041 agctgtcact caaccacaag aatggtttga tttgattcaa acagctgaaa aaaataactg
    32101 ttttatcttt gaagcagctc gtaattatca cgagaaagcc tttactacta tcaaaaactt
    32161 tttagcagat aagcaagtgt taggagcaga tttcaactat gccaaatact cttccaagat
    32221 gcctgactta ttggctggac aaacaccaaa tgtcttttca gaccgttttg ctggtggagc
    32281 cctcatggat ttggggattt atcccctcta tgctgctgtt cgtctttttg aaaaagctaa
    32341 tgacgcgact taccatgctc aacagcttga caatagcatt gacctaaatg gagatggtat
    32401 cctcttctac ccagactatc aagttcacat caaggctgga aaaaacatca cttccaatct
    32461 tccttgcgag atttatacaa cagatggaac cttgactctc aacacgattg agcatattcg
    32521 ctcagctatt tttaccgacc accaaggaaa tcaagtccag cttcctatcc aacaggctcc
    32581 tcatacgatg actgaggaag tcgctgcatt tgcacacatg atccagcaac cagatctgaa
    32641 tctctaccaa acttggctgt atgatgcagg ctctgttcat gagctactat ataccatgcg
    32701 ccagactgct ggcgttagat ttgaggcaga aaaatgaaaa ccaaactacc gactgaatgg
    32761 caagaactga gtgaccaact cggtttccaa gaattcaccc ccattcaaac tcaactattt
    32821 gagctccttc ttgctggaga aaacctccta ggagtgagcc aaaccggaac tggtaagacc
    32881 ctagcgtatc tcctaccaag tcttctcaga ctacaaaaga aaaaagccca acaactcttg
    32941 attctagcac caaacacgga acttgctgga cagatttttg atgtatgtaa aacgtgggca
    33001 gaagctatcg gattgactgc tcaactcttc ctttcaggtt caagtcagaa acgacaaatt
    33061 gaacgtctta aaaaggggcc agaaattctg attggaactc ctggccgtat ctttgaactc
    33121 attaaactta aaaaaatcaa gatgatgaat gtggaaacca tcatcctgga tgaatttgac
    33181 caattactag atgattctca gattcacttt gtagagaaaa tcactcacta cgcacctcgt
    33241 gaccaccaac tggtctacat gagtgccacg accaagtttg accaagaaaa gattgtgccg
    33301 aatacacgca ctattgatct ctctgatcaa aaattggaca atatccagca tttctacatg
    33361 caggtagacc aacgtcatcg agtggatatg ctacgaaaac tggctcatgt agaggatttc
    33421 cgtggtctag tcttcttcaa tagcctgtca gaccttggga atgccgagga aaaactacag
    33481 tatcgtgata tattggctgt ttccctcgct agtgatgtta atgttaaatt tagaaaaatc
    33541 atcttagaaa agtttaaaga taaccaacta accctgcttc ttgcaactga ccttttggct
    33601 cgtggaattg atatcgatag cctagaatgt gtcgtaaact ttgatattcc tagagatagc
    33661 gaaacctaca cacaccgtgc tggccgtact ggtcgtatgg gcaaggaagg ttatgttatc
    33721 actctcgtca ctcatccaga agaaatcaaa aaacttaaaa agtttgcaag tatccgagaa
    33781 attgtcctaa aaaaccaaga actctatatc aaataaagcc ccattgctct atacacatcc
    33841 agtgtatgga gcttttttat aagcaattca attttatact catctgcttt caaaaagcat
    33901 tctagtccat ctccgattaa cgatggactt tatcacctcc ttctccaatc cttgtatgac
    33961 atcttgaagt tgattcatga catcttccaa aattcgaaag gctttattct taaatccacg
    34021 tttacgaatc tctttccaca cttgttcaat ggggttcatc tctggtgtgt atggaggaat
    34081 aaatgcaaaa ccaatattag tcggaatctt taagatactt gatttatgcc atatagcatt
    34141 gtccataacg agtaaaaaat aatcatctgg ataagcttgt gaaagctctt ctaaaaaggc
    34201 gttcatccac tcagtattac atctaccagc tattaagaaa aatgattcgc ctgtatgggc
    34261 atcaacagct ccataacaat agcgaaattc tcgtatatag tgactatgga tatgtggacc
    34321 tactcctatt ggagcccaac aagatcccag tttactgatt ctaccgaaac cagcctcatc
    34381 ttggtacatc aagcgaacct tacgaaaacg tctactatat ttaaaacgct ttcttgtctt
    34441 cttgaattga gattttattt ttagacgcga caatggtttg agcgtctgct ttcttaggat
    34501 gttctggacg tggcataata tttcgccaac catggcgctt caacagttga tagaaggcat
    34561 cacgtgtgta ggaacgacct aactcctttt tataagcctg aaataaggca tcaattgtaa
    34621 caaattctcc tgcctctgca gccttcaaat ggcgggcaag aaag
//
LOCUS       DBJKQU010000019        33446 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.019, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000019 DBJKQU010000000
VERSION     DBJKQU010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33446
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.019"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(<1..362)
                     /locus_tag="ACSUUC_001013"
     CDS             complement(<1..362)
                     /locus_tag="ACSUUC_001013"
                     /inference="COORDINATES: protein motif:HMM:NF025126.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HHQ8054239.1"
                     /translation="MFDKKQKRGYKESAKNLANWHYNDKEDSYTHPDGWYYRFHHTKH
                     QKTQTDFQQEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQRKI
                     DVEPVFGQIKASLGYKRC"
     gene            complement(527..772)
                     /locus_tag="ACSUUC_001014"
     CDS             complement(527..772)
                     /locus_tag="ACSUUC_001014"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054240.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEDCHFHAF
                     YHAFDRLSYHLKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            complement(984..1343)
                     /locus_tag="ACSUUC_001015"
     CDS             complement(984..1343)
                     /locus_tag="ACSUUC_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HHQ8054241.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            1435..2391
                     /locus_tag="ACSUUC_001016"
                     /pseudo
     CDS             1435..2391
                     /locus_tag="ACSUUC_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            2375..2932
                     /locus_tag="ACSUUC_001017"
     CDS             2375..2932
                     /locus_tag="ACSUUC_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHQ8054242.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            2925..3179
                     /locus_tag="ACSUUC_001018"
     CDS             2925..3179
                     /locus_tag="ACSUUC_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054243.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            3191..5245
                     /locus_tag="ACSUUC_001019"
     CDS             3191..5245
                     /locus_tag="ACSUUC_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HHQ8054244.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLIWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHSFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            5429..6289
                     /locus_tag="ACSUUC_001020"
     CDS             5429..6289
                     /locus_tag="ACSUUC_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HHQ8054245.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            6500..7210
                     /gene="ccdA2"
                     /locus_tag="ACSUUC_001021"
     CDS             6500..7210
                     /gene="ccdA2"
                     /locus_tag="ACSUUC_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HHQ8054246.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            7230..7796
                     /locus_tag="ACSUUC_001022"
     CDS             7230..7796
                     /locus_tag="ACSUUC_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HHQ8054247.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            7807..8919
                     /gene="msrB"
                     /locus_tag="ACSUUC_001023"
     CDS             7807..8919
                     /gene="msrB"
                     /locus_tag="ACSUUC_001023"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HHQ8054248.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKTVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            9187..9924
                     /locus_tag="ACSUUC_001024"
     CDS             9187..9924
                     /locus_tag="ACSUUC_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHQ8054249.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            9921..11612
                     /locus_tag="ACSUUC_001025"
     CDS             9921..11612
                     /locus_tag="ACSUUC_001025"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cache domain-containing sensor histidine kinase"
                     /protein_id="HHQ8054250.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSAGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            11728..12291
                     /locus_tag="ACSUUC_001026"
     CDS             11728..12291
                     /locus_tag="ACSUUC_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HHQ8054251.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            12313..17976
                     /locus_tag="ACSUUC_001027"
     CDS             12313..17976
                     /locus_tag="ACSUUC_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HHQ8054252.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGTMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDPTKYTDEET
                     VLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPIEGTTVETR
                     EEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAPTITETVIE
                     KPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSIKVALKDNT
                     GTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKEVQLDLKKV
                     EIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLAITNIEEVT
                     EEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDLVDAMQKNP
                     NGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFDRVEGGSIK
                     NINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDKLDDAGIMT
                     NVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIVGHLAHDFN
                     PRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKRGDIFFGSN
                     DMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMGITADTFEV
                     TEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQGNKLTTDS
                     PLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVKQVKEYSVA
                     ELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVNAIKNLYLE
                     ESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGLTYLNRYYG
                     VKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFREVVAKNTLS
                     GNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYRLYEGLNNG
                     QHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRETFKSEINKRAKEQVN
                     YLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPDYAPIREFF
                     GRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETTHVNDRMAY
                     LGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQWYNPDPTKL
                     QTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRPMDRNKLSG
                     PHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTAYVNVNMMA
                     GIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKENNGLLGDDF
                     IIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKTMFDEAVTK
                     DLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            18045..19766
                     /gene="pabB"
                     /locus_tag="ACSUUC_001028"
     CDS             18045..19766
                     /gene="pabB"
                     /locus_tag="ACSUUC_001028"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - 4-aminobenzoate biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HHQ8054253.1"
                     /translation="MHRKTVIDFRTLGERYTFTKPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            19767..20384
                     /locus_tag="ACSUUC_001029"
     CDS             19767..20384
                     /locus_tag="ACSUUC_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HHQ8054254.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSRCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            20434..21432
                     /locus_tag="ACSUUC_001030"
     CDS             20434..21432
                     /locus_tag="ACSUUC_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HHQ8054255.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            21559..22518
                     /locus_tag="ACSUUC_001031"
     CDS             21559..22518
                     /locus_tag="ACSUUC_001031"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HHQ8054256.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            22615..23454
                     /locus_tag="ACSUUC_001032"
     CDS             22615..23454
                     /locus_tag="ACSUUC_001032"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HHQ8054257.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(23502..23672)
                     /locus_tag="ACSUUC_001033"
     CDS             complement(23502..23672)
                     /locus_tag="ACSUUC_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HHQ8054258.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            23793..24677
                     /gene="miaA"
                     /locus_tag="ACSUUC_001034"
     CDS             23793..24677
                     /gene="miaA"
                     /locus_tag="ACSUUC_001034"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HHQ8054259.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            24670..25908
                     /gene="hflX"
                     /locus_tag="ACSUUC_001035"
     CDS             24670..25908
                     /gene="hflX"
                     /locus_tag="ACSUUC_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HHQ8054260.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            25901..26524
                     /locus_tag="ACSUUC_001036"
     CDS             25901..26524
                     /locus_tag="ACSUUC_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HHQ8054261.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLKEAAAFSGKRYFRSENRTAMLYID"
     gene            26539..27468
                     /gene="rnz"
                     /locus_tag="ACSUUC_001037"
     CDS             26539..27468
                     /gene="rnz"
                     /locus_tag="ACSUUC_001037"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HHQ8054262.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAKKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKDDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            27489..28244
                     /locus_tag="ACSUUC_001038"
     CDS             27489..28244
                     /locus_tag="ACSUUC_001038"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HHQ8054263.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(28298..29206)
                     /locus_tag="ACSUUC_001039"
     CDS             complement(28298..29206)
                     /locus_tag="ACSUUC_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHQ8054264.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            29270..29539
                     /locus_tag="ACSUUC_001040"
     CDS             29270..29539
                     /locus_tag="ACSUUC_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HHQ8054265.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            29539..29919
                     /locus_tag="ACSUUC_001041"
     CDS             29539..29919
                     /locus_tag="ACSUUC_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HHQ8054266.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            30008..30235
                     /locus_tag="ACSUUC_001042"
     CDS             30008..30235
                     /locus_tag="ACSUUC_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054267.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(30275..31000)
                     /locus_tag="ACSUUC_001043"
     CDS             complement(30275..31000)
                     /locus_tag="ACSUUC_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HHQ8054268.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            31162..33003
                     /gene="typA"
                     /locus_tag="ACSUUC_001044"
     CDS             31162..33003
                     /gene="typA"
                     /locus_tag="ACSUUC_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HHQ8054269.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDSTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            33023..33277
                     /locus_tag="ACSUUC_001045"
     CDS             33023..33277
                     /locus_tag="ACSUUC_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HHQ8054270.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
BASE COUNT        10111 a         6160 c         7487 g         9688 t
ORIGIN      
        1 ttacatctct tgtaacccaa agaagccttt atctgcccaa agacaggttc cacatcaatc
       61 ttgcgttgag cgaaaatctg tctaccttgg ggagataaaa gcgcctgaca ttctttagct
      121 ttcaagtttt gatagcgttc gttcatatat agtccctttt gaggggctga ttcaggttcg
      181 tcggcgtagt aaaccttgat ttcctgttga aagtctgtct gtgttttctg atgtttggta
      241 tggtgaaaac gataatacca gccatcagga tgtgtgtagc tatcctcctt gtcattatag
      301 tgccaattcg ctaagttttt agctgactct ttataccctc tcttttgttt cttatcaaac
      361 atggcatatt taatcaggag gggagtgatt tcttcttgaa aatagacttg tatctgttct
      421 tgaagtttgg cggagaattt ctctgtcgtt ttcttccaca caaaactata cttgttggca
      481 ttggcttcaa tcttagttcc gtcaataaac aaacaatcta aggtcactaa ctcttccatt
      541 tttcaatttt tcgaccagag aaaatccctt gtgaataggc aaatagaaga gtagatacaa
      601 gcattttaag gtgataagac aggcgatcaa aggcatgata gaaggcgtgg aaatgacaat
      661 cctccaaggt attcaccact ttttcaatag taaaaacgag atggtcttgt ggcaagaagg
      721 aactgatttc tagtggtaaa gttgtttgat ttgtgttata gtgaatatgc atgggatagc
      781 ctttctaaat ggtttattgg gcaattctat tttaccaaga ctatcgtaac catgcaaaaa
      841 aagcaacggc aaatccgttg ctttttttgg agataagaga ctattgtccc agactctttt
      901 ctttgtataa aattgtatag tgttattgtc tatactattt tgtagagaaa gaaaaaatcc
      961 ctagaaaatg cttagggatt cgactatttc attaagaaca attcaacaat catttctaca
     1021 tacatgataa gggttaataa gaatcctgca cgccagaaga atttgatgaa tttaggatag
     1081 taaaagctgc gttttttcaa aaggaagaaa aagacgagaa taatggctag gatcgagagg
     1141 gctagcccca gtctagggag gaaattatgg gtaaaggttt tagctgtaat caggtaatat
     1201 tcaaatacca agaccggaaa agccaaatcc gcaaagtttc gtcctagttt ttttaatcta
     1261 aaaagtttgg ttaggataat gcagacgact aaggtcagta tcaataataa aatagatgct
     1321 aatttcatta aaatcatacc catattgtat cataaaaaaa ggctaatgga aacgagaaac
     1381 agaggaattt ataggaaagt caggcttttg agattgtggg tgatttttgt tataatgaaa
     1441 gtcatgaaat cttataatac cttgaatgat tattatcgaa aattctttgg agaaaagact
     1501 tttaaagtcc ctattgatgc gggatttgac tgtcccaatc gtgatggaac tgtggctcat
     1561 ggaggctgta ctttttgtac ggtttcaggt tctggagatg ctattgtagc cccagatgcg
     1621 cctatccgtg agcaatttta taaggaaatt gactttatgc accgtaagtg gccggatgtt
     1681 cagaagtatc tggtttattt tcaaaatttt accaacaccc atgaaaaggt ggaagttatt
     1741 cgagagcgtt atgaacaggc tatcaatgag ccaggtgtgg taggtatcaa tattggaacg
     1801 cgcccagact gtttaccaga cgaaaccatc gaatatttgg ctgagttatc ggagtgcatg
     1861 catgtgacgg ttgaattggg cttgcagacc acttatgaag caacctctga cctgattaac
     1921 cgtgtgcatt cttatgaatt gtaggtggaa acggtcaagc gtttgagaaa gtatcccaag
     1981 attgagattg ttttccattt gatcaatggc ttgcctggtg aaacccatga gatgatggtt
     2041 gaaaatgtcc gccgttgtgt cacggataac gatattcaag ggattaaact gcatttgctc
     2101 catcttatga caaatactcg tatgcaacga gattaccatg agggacgttt acaattgatg
     2161 agtcaggacg aatatgtcag ggtcatctgt gaccaactgg aaattattcc caaacatatc
     2221 gtcatccatc gaattacagg agatgcgcct agggatatgc tgattggtcc tatgtggagc
     2281 ctcaaaaaat gggaagtcct caacagcatt gagatggaga tgcgacgtcg tggaagtgtt
     2341 caaggatgca aggctgtaaa acaggagttt gaaaatgaaa agaccacttg agatggcaca
     2401 tgattttttg gctgaggtcg tgacaaaaga ggatgtcgta gtggatgcga ctatgggaaa
     2461 tggtcatgac acgctttttt tagccaagct agccaagcaa gtctatgcct ttgatattca
     2521 gaagcaagcc ttggaaaaga cccaagagcg tttgcatcag gctggcttga caaatgccca
     2581 gttaatcttg caaggccatg agacactgga ccagtttgtg acaaaagcta aggcagggat
     2641 ttttaatctg ggctatttgc cgtcagctga taagtctgtc atcacccgac cgcagacaac
     2701 gattgaggca ttagaaaagc tatgtggctt acttgtcaaa ggtggacgaa ttgctattat
     2761 gatttactat ggtcatgaag gaggcgacct cgagagagat gctgtcttgg attttgtgat
     2821 ccagttgaac caacaagagt acacagctgc catttaccga actttaaacc aagtcaacaa
     2881 cccgccgttt ttagtgatga ttgaaaaatt agagagatac agacatggat aaacaatacc
     2941 tacacgaaaa gctggatgcc atgcgccaga attttgttga atcaactcac cacgaacgag
     3001 cggtgggcgt gctagaccaa gcgcatatga gcaaaaaaat gcttaaaatc aagaaaaaat
     3061 tagttgctct tgaaatggaa cggtgccaga gaaaaattga gcacaaagac tgttccaaga
     3121 ttgaccaaaa aatcaaagag cagaaggaga tatttgaatc ctgttgtaaa aaagattaag
     3181 gaggacgtgc gtggaattac tgatttacct catcctattt ttactggttt tgattgtctc
     3241 aagtacaacc aataagctcc tacccttttt gcctctccct ttggtgcaga ttcttttggg
     3301 aattgtgatt ggtctctttt tacccaatac tgactttcat cttaatacgg agttgttttt
     3361 ggccctggtt atcggaccct tgcttttccg agaggctgaa gaagcagatg ttacggctat
     3421 tttaaaacac tggcgaatca ttgtttatct catatttcca gtgattttta tctcgaccct
     3481 gagtttgggt ggcttggccc atcttatttg gttcagcctt cccttggcag cttgcttggc
     3541 tgttggggca gcccttggtc ctacggactt ggtggccttt gcctctcttt cggagcgttt
     3601 tagctttcct aagcgcgtgt ccaatattct taagggcgaa ggactcttga atgatgcttc
     3661 tggtttggtg gcttttcagg tagctttgac agcttggaca actggagctt tttctctggg
     3721 gcaagctagc agttcgctca tcttttcaat cctaggcggt tttttaattg gctttttaac
     3781 agccatgacc aatcgtttcc tccatagctt cttgctaagt gtgagagcaa cggatattgc
     3841 tagtgagctc cttctggaat tgagtttgcc cttggtaacc ttcttcctgg cagaagaagt
     3901 ccatgtttca gggattattg ccgtcgtagt tgctggaatt ttaaaggcaa gtcgcttcaa
     3961 gaaaatcacg ctcctcgaag cccaagtgga tacggtgacc gagacggtct ggcatacagt
     4021 gacctttatg ctcaacggtt ctgtctttgt gattttaggg atggagttgg aaatgatagc
     4081 agaacctatc ttgaccaatc caatctataa tcctctactt ttattgctat ctctcatcgc
     4141 ccttaccttt gtcctctttg tcattcgttt tattatgatc tatggctatt atgcctatag
     4201 aacccgacgc ctcaagaaaa agctaaataa gtatatgaag gacatgtttc tcttgacctt
     4261 ttcaggtgtt aagggaacgg tgtcgattgc tacgattctc ttgataccaa gtaatctaga
     4321 acaggagtat cctctcttgc ttttccttgt tgcaggtgtg acgcttgtca gctttttaac
     4381 aggtctcttg gtcttgcctc atctttctga tgaagaggaa gaaagcaagg attatctcat
     4441 gcatatcgcc attttgaatg aagtaacgct agagttggaa aaagagttgg aagacactag
     4501 aaataaactt cccctctatg cggctattga caattatcat ggacgtattg aaaatctcat
     4561 tttaagccaa gaaaaccagg atgatcaaga agactgggct gctttgaaac tcttgattct
     4621 tagtattgaa agtgatggtt tggaacaggc ctatgaagag gggaacatta gcaatcgtgc
     4681 ttaccgagtt taccaacgtt atctgaaaaa tatagaacaa ggaatcaatc gtaaacttgc
     4741 ctcaagactg acctattatt ttcttgtttc cttgaggatt ttacgttttc tccttcatga
     4801 agtttttact ctcggaaaga ccttccgtag ctggaagaac aaggagcaaa gccgtctccg
     4861 tgctcttgat tatgaccaaa ttgcagagct ctatcttgcc aatacagaga tgattattga
     4921 aagtttggaa aacctgaagg gagtctacag acgctctttg attagtttta tgcaggagtc
     4981 tcgtcttcga gaaacagcta ttatcagcag tggtgccttt gtcgaacggg ttatcaatcg
     5041 tgtcaaaccc aacaatatcg atgaaatgct gagaggctat tatctggagc gcaagttgat
     5101 tttcgaatac gaagaaaaac gattgattac gactaagtat gccaagaaat tacgacaaaa
     5161 tgtaaataac ttagagaact attccttgaa ggaagctgcc aataccctac cgtatgatat
     5221 ggtggaattg gtaagaagaa attagttaat actcttcgaa aatctcttca aaccacgtca
     5281 gcgtcgcctt accgtatgta tgtgactgac ttcgtcagtc ttatctacaa cctcaaaaca
     5341 gtgttttgag cagcttgcgg ctagctttct agtttgctct ttgattttca ttgagtataa
     5401 gattataagt gaaggagtat gatatgacat gaaaaagtgg tggaaagagc tgatagacaa
     5461 acctttatta aaagcttttt tgcattatta tcaagcatca gatagtgagt tgaccagtgt
     5521 cgcagtagcc tactattggt tgatttcgat tttccccctg cttttggtgg tggtcaatat
     5581 cctcccctat tttcagattc ctgtgggaga atttttgggc tttatgaaag acgttctgcc
     5641 cccaagcctc tatgaaggtg tggaaaaaat agccagagaa gttttgacgc aaccttcaac
     5701 aggtttattg agtttttctg ttttatcggc gttatggagt ttttcaaaat ctatgaattt
     5761 cttgcaaaaa gcttttaaca aggcttatgg cgtcgaaaag agtcgtggac ttatttccca
     5821 tcagatgctg agtctcctag tcagttttgg cttgcagctc ctctttgcgt ttgccttgtt
     5881 tttgatctta tttggtcaga tgattttggc tttacttgct cattattgga caaaagatgg
     5941 cattatctat caggctttac aagggttggc aggtcctctg atttacgccc tcctctttgc
     6001 tatcttggtc atgctttatt attttcttcc caatctatct aacaggaaaa ttagctatac
     6061 cctaccaggc agtgcctttg ttctcttagt gattttaggt ttactaactc tgttctctag
     6121 ttatctcaat tactatgtcc atcatttggt ggatgtccga attttaggtt ccgttcttct
     6181 tgttgttatg atgttttggt ttatcttgat tgctaaaatt gttatcctag gcgcggttat
     6241 caatgccagt atgcagagtt tgaaagatcc ggtctttaaa aaagactaac tatttatcta
     6301 ttataaaagc gcatagtatc aagactttat agaaccttga tactatgcgc ttttgtgctt
     6361 tgacagtttt ttgtatagtt tttgtccaag atttctaaat catctgatta aattcctatt
     6421 ttcccctatc attgtccctg ttttttcgaa aatggaagga gtataataaa tctatcaata
     6481 aaatgatagg aggaacttta tgggtcatat tttctttttt ctaagtgtct ttttggcagg
     6541 gattctatcc ttcttttctc cttgtatctt acctttgtta ccggtctata caggggtgtt
     6601 actagatgat aaggatggtg ctcaggcttc tagcggcaaa ttttcaatct cagttactag
     6661 tttattacga actctggcct ttatagcagg aatttccttt atatttattt tgttgggcta
     6721 tggagctggt tttttaggcg atttgcttta tgcttcttgg ttccaatatc ttactggggc
     6781 aattattatc cttcttggtt tgcaccaaat ggagattcta cactttaagg ggctttataa
     6841 ggaaaagagg ctacaactgc aaggacaggg gcaaaatggt aagggctata gtcaggcatt
     6901 tttattgggc ttgaccttta gttttgcttg gacgccttgc gtggggccgg ttctggggtc
     6961 tgttttggcc ttggcggctt caggtggttc aggagcttgg cagggagctg gtctcatgtt
     7021 ggtgtatacg ctgggcttgg cgctaccatt cttgcttcta gctctgacct ctagttatgt
     7081 tttgaaacat ttccgaaaac ttcatcccta tctcggaatc ctcaaaaaag tgggaggttt
     7141 tctcattatt gtgatgggac tcttggttct gtttggaaat gcttcaattt taagtcaatt
     7201 atttgaataa aatggaaagg aatatcaata tgaaaaaatg gcaaacatgt gttcttggag
     7261 cgggttcgct cctttgtttg acggcttgtt caggcaagtc cgtgactagt gaacaccaaa
     7321 cgaaagatga aatgaagacg gagcagacag ctagtaaaac aagcgcagct aaagggaaag
     7381 aggtggctga ttttgaattg atgggagtag atggcaagac ctaccgttta tctgattaca
     7441 agggcaagaa agtctatctc aaattctggg cttcttggtg ttccatctgt ctggctagtc
     7501 ttccagatac ggatgagatt gctaaagaag ctggtgatga ctatgtggtc ttgacagtag
     7561 tgtcaccagg acataagggg gagcaatctg aagcggactt taagaattgg tataagggat
     7621 tggattataa aaatctccca gtcctagttg acccatcagg caaacttttg gaaacttatg
     7681 gtgtccgttc ttacccaacc caagccttta tagacaaaga aggcaagctg gtcaaaacac
     7741 atccaggatt catggaaaaa gatgcaattt tgcaaacttt gaaggaatta gcctaggagg
     7801 tgtcttatga atgataagtt aaaaatcttc ttgttgctag gagtattttt tctagccata
     7861 accggtttct atgttctatt gatacgaaat gcagggcaga cagatgcctc gcaaattgaa
     7921 aaggcggcag ttagccaagg aggaaaaaca gtgaaaaaaa cagaaattag taaagacgca
     7981 gacttgcacg aaatttatct agctggaggt tgtttctggg gagtggagga atatttctca
     8041 cgcgttcccg gggtgacgga tgccgtttca ggctatgcaa atggtagagg agaaacaacc
     8101 aagtacgaat tgattaacca aacaggtcat gcagaaaccg tccatgtcac ctatgatgcc
     8161 aagcaaattt ctctcaagga aatcctgctt cactatttcc gcattatcaa tccaaccagc
     8221 aaaaataaac aaggaaatga tgtggggacc cagtaccgta ctggtgttta ttacacagat
     8281 gacaaggatt tggaagtgat taaccaagtc tttgatgagg tggctaagaa atacgatcaa
     8341 cctctagcag ttgaaaagga aaacttgaag aattttgtgg tggctgagga ttaccatcaa
     8401 gactatctca agaaaaatcc aaatggctac tgccatatca atgttaatca ggcggcctat
     8461 cctgtcattg atgccagcaa atatccaaaa ccaagtgatg aggaattgaa aaagaccctg
     8521 tcacctgagg agtatgcagt tacccaggaa aatcaaacag aacgagcttt ctcaaaccgt
     8581 tactgggata aatttgaatc cggtatctat gtggatatag caactgggga acctctcttt
     8641 tcatcaaaag acaaatttga gtctggttgt ggctggccta gttttaccca acccatcagt
     8701 ccagatgttg tcacctacaa ggaagataag tcctacaata tgacgcgtat ggaagtgcgg
     8761 agccgagtag gagattctca ccttgggcat gtctttacgg atggtccaca ggacaagggc
     8821 ggcttacgtt actgtatcaa tagcctctct atccgcttta ttcccaaaga ccaaatggaa
     8881 gaaaaaggct acgcttattt actagattat gttgattaat actcttcgaa aatctcttca
     8941 aaccacgtca gcgtcgcctt accgtatgta gggttactga cttcgtcagt tttatctaca
     9001 acctcaaagc tatactttga gctgacttcg tcagttttat ctacaacctc aaagcggtac
     9061 tttgagaaac ctgtggctat cttcctagtt tactttttga tttttattga gtataagagg
     9121 tctttcctaa gcagttagag gagaattttg ctatactgat actagtaaat ggtaaaggag
     9181 cagagcatga cctacacaat cttaatcgta gaagatgaat atctggtaag acaaggtttg
     9241 actaaactgg tcaatgtagc agcctacgat atggaaatca tcggtcaggc tgaaaatgga
     9301 aggcaggctt gggaattgat ccaaaagcag gttccagata tcattttaac cgatatcaac
     9361 atgcctcatc taaatggcat ccagttggcc agtttggtac gagaaaccta tcctcaggtt
     9421 catttggtct ttttaacagg ttacgatgat tttgattatg ccttgtctgc tgtcaaacta
     9481 ggtgtggacg actacctgct caaacccttt tctcgtcagg atattgagga aatgttgggg
     9541 aaaatcaaac aaaaactaga caaggaagag aaagaagagc agttacaaga tttattgact
     9601 aataggtttg aaggaaacat ggcccagaaa atccagtctc atctggctga tagccaattt
     9661 agtttaaagt ctttagccag tgacttaggt tttagtccga cctatctgag ttctttgatt
     9721 aagaaagagt tgggcttgcc ttttcaggat tatctggtga gagaacgtgt taaacaagcc
     9781 aagctcttgc ttttaactac agatctgaag atttatgaga tcgcagagaa ggttggtttt
     9841 gaagatatga actattttac ccaacgtttt aagcagattg caggtgtgac acctcgtcag
     9901 tttaagaagg gagaagaccg atgaagcgtt cttctctttt agttagaatg gttatttcca
     9961 tctttctggt ctttctcatt ctcctagctc tggttggaac tttctactat caatcaagtt
    10021 cttcagccat tgaggccacc attgagggca acagccaaac gaccatcagc cagactagcc
    10081 actttattca gtcttatatc aaaaaactag aaaccacctc ggctggtttg acccagcaga
    10141 cggatgttct ggcctatgct gagaatccca gtcaagacaa ggtcgaggga atccgagatt
    10201 tgtttttgac catcttgaag tcagataagg acttgaaaac tgttgtgctg gtgaccaaat
    10261 ctggtcaggt catttctaca gatgacagtg tgcagatgaa aacttcctct gatatgatgg
    10321 ctgaggattg gtaccaaaag gctattcatc agggagctat gcctgttttg actccagctc
    10381 gtaaatcaga tagtcagtgg gtcatttctg tcactcaaga acttgttgat gcaaagggag
    10441 ccaatcttgg tgtgcttcgt ttggatattt cttatgaaac tctggaagcc tatctcaatc
    10501 aactccagtt ggggcagcag ggctttgcct tcattatcaa tgaaaaccat gaatttgtct
    10561 accatcctca acacacagtt tatagttcgt ctagcaaaat ggaggctatg aaaccctaca
    10621 tcgagacagg tcagggttat actcctggtc acaaatccta cgtcagtcaa gagaagattg
    10681 caggaactga ttggacggta cttggcgtgt catcattgga aaagttagac caggttcgga
    10741 gtcagctctt gtggaccttg cttggggcca gtgtcacatc tcttcttgtc tgtctctgct
    10801 tagtgtggtt cagtcttaaa cgctggattg ctcctttgaa ggatttgaga gaaaccatgt
    10861 tggaaattgc ttctggtgct caaaatcttc gtgccaagga agttggtgcc tatgaactga
    10921 gagaagtaac tcgccaattt aatgccatgt tggatcagat tgatcagttg atggtagcta
    10981 ttcgtagcca ggaagaaacg acccgtcagt accaacttca agccctttcg agccagatta
    11041 atccacattt cctctataac actttggaca ccatcatctg gatggctgaa tttcatgata
    11101 gtcagcgagt ggtgcaggtg accaagtcct tggcaaccta tttccgcttg gcgctcaatc
    11161 aaggcaagga cttgatttgt ctctctgacg aaatcaatca tgtccgccag tatctcttta
    11221 tccagaaaca acgctatgga gataagctgg aatacgaaat taatgaaaat gttgcctttg
    11281 ataatttagt cttacccaag ctggtcctac aaccccttgt agaaaatgct ctttaccatg
    11341 gcattaagga aaaggaaggt cagggccata ttaaactttc tgtccagaaa caggattcgg
    11401 gattggtcat ccgtattgag gatgatggcg ttggcttcca agatgctggt gatagtagtc
    11461 aaagtcaact caaacgtggg ggagttggtc ttcaaaatgt cgatcaacgg ctcaaacttc
    11521 attttggagc caattaccag atgaagattg attctagacc ccaaaaagga acgaaagttg
    11581 aaatatatat aaatagaata gaaactagct aactcccagt caattctggg agttttatgc
    11641 gtaattgggc aaactttcta ggttgtctat cttgctaaaa acaagaaaaa acggtatgat
    11701 agaagagtga caacagaggt aacagagatg aacgagacac agattcaaag agaaacacgt
    11761 caggtagtgg aagatgtttt agaaaagacc aatttgaaac agggggccct ttttgtttta
    11821 ggtctatctt ctagtgaggt gctaggtggt cagattggga aagaatccag tcaagagatt
    11881 ggtgagctga tagtggagac tatcttgggt attctaggta gtagaggtat ccatttagca
    11941 gttcaaggtt gtgagcatgt caatcgggct ctcgttgttg aacgtcaggt ggcagagcag
    12001 tttggtctgg aaattgtcag tgtccatcct actcttcatg caggaggttc ggggcagttg
    12061 gcagccttta agtttatgca ggatccagtt gaggttgaat ttatcaaggc tcatgctgga
    12121 ttggatatcg gagacactgc aattggcatg catgtcaagc atgttcaggt tccgattcgc
    12181 cctattttga gagagattgg tcatgcccat gtaacggcac tgactagtcg tccaaaatta
    12241 atcggaggtg cgcgtgcgca ctatccgcaa gatgctatta ggaagttttg agaatgaata
    12301 aaggagataa aagtgtttaa aaaagaccgt ttttcaattc gtaagattaa gggagttgta
    12361 ggctctgtat ttcttggaag ccttttgatg gctccttctg tagtggacgc agccacctat
    12421 cactatgtaa ataaagagat tatttcacaa gaagctaaag atttaattca gacaggaaag
    12481 cctgacagga atgaagttgt atatggtttg gtgtatcaaa aagatcagtt gcctcaaaca
    12541 gggacagaag catctgtttt gacagctttt ggtttgctga ctgttgggag cttgctttta
    12601 atctacaaga gaaagaaaat tgctagcgtc tttctagttg gaactatggg attggtagtt
    12661 cttcctagtg caggggctgt agacccagtt gcgaccctag cactggctag tcgagagggt
    12721 gttgttgaaa tggagggcta tcgctatgtt ggttatctat caggtgacat cctcaaaacg
    12781 cttggcttgg acactgtttt agaagaaacc tcagcaaaac ctggagaggt gactgtagtc
    12841 gaagttgaga ctcctcaatc aacaacaaat caggagcaag ctaggacaga aaaccaagta
    12901 gtagagacag aggaagctcc aaaagaagaa gcacctaaaa cagaagaaag tccaaaggaa
    12961 gaaccaaaat cggaggtaaa acctactgac gacacccttc ctaaagtaga agaggggaaa
    13021 gaagattcag cagaaccagc tccagttgaa gaagtaggtg gagaagttga gtcaaaacca
    13081 gaggaaaaag tagcagttaa gccagaaagt caaccatcag acaaaccagc tgaggaatca
    13141 aaagttgaac aagcaggtga accagtcgcg ccaagaaaag acgaacaggc accagtcgag
    13201 ccagaaaatc aaccagaagc tcctgaagaa gagaaggctg tagaggaaac accgaaacaa
    13261 gaagagtcaa ctccagatac caaggctgaa gaaactgtag aaccaaaaga ggagactaaa
    13321 acagctaagg ggacgcaaga agaagattac gtgggtgagg ctcttgttcc agaacaatta
    13381 cctgagtata aggtgactga aggaacactc gttgaagaat caactacaga acttgactat
    13441 aaaactgaaa cgactgagga cccaaccaag tacacggacg aagaaactgt cctacgaaat
    13501 ggtgaaaaag gaagtcaagt tacaaaaaca acctataaaa caataggagg ggttaaaact
    13561 gaccaagttc tttcaaccag tacggaagtc accaaggagc ctgtaaatca acaggtaatc
    13621 cgtggtacaa aaccaattga agggacaacg gttgagacaa gagaagaaat cattcctttt
    13681 gaaacaaaag aacaagaaga tgacacttta aaacgcggaa caagacaagt aactcaagaa
    13741 ggtgtaaacg ataagaaaca aattactgaa acctataaaa caattcgcgg agaaaaaaca
    13801 agtgacgctc ctactatcac agaaacagtg attgaaaaac ctcaagacaa aattattaag
    13861 aatggcacaa aagagttaga gaaaccaacc ttggaatggg ctaaaacaga taaagatgtc
    13921 ttgaagaaga gtgcgacagc tagttataca ttgactaaac cagctggagt agaaattaaa
    13981 tcgattaaag tagctctaaa agataatact ggaacagttg ttaaagaagt aacggtagaa
    14041 gaaaataact tacaagctac tttagacaac ttgaaatatt atcaaggtta tacactatcc
    14101 acaaccatgg tctatgatcg aggtaacggt gaagaaactg aaatattaga agataaagaa
    14161 gttcagttag accttaaaaa agttgagatt aaagatatta aagaaacaag attgatgaaa
    14221 gtggatgaga atggaaatga aacagatagt agccttctag aaactgttcc agaaaatcta
    14281 acgtcatatt atctaaaaat taccactaat cataataaag taacaaggct tgccattact
    14341 aatatagagg aagtaactga ggaggagaca tccttattta aagttactgc ttcagctcct
    14401 gatttaatcc aacgtgattc aaataatagt ttgagtcaaa catacactta ttacatagag
    14461 aaacccaaag catcgcaaaa taacgtttac tataacttca aagatttagt agatgctatg
    14521 cagaaaaatc ctaacggtga gtttaaatta ggatcggatt taaatgcaac aaatgtacct
    14581 acaccaagta aatcatatgt aacaggtaaa tttacaggtc acttaacaag tgttgatggt
    14641 aagcatttct ccattcataa cactgctcgt ccattatttg atagagttga agggggttct
    14701 atcaaaaata ttaatttaat taacgttaat attaatatgc cttgggcaaa tcaattagct
    14761 tcattagctc aaacagtgaa aaatgcaact gttgaaaata ttaaagtaac gggtactatc
    14821 gttggtaata acaatgttgc gggtattttg gataaattag atgatgcagg tattatgact
    14881 aatgttgctt ttatcggaaa agttcaatct gttggtgata aagggtggaa cttggctggg
    14941 attgcatctg agatttatcg aggcaattta aataaagctt atgcagatgt tgaacttaaa
    15001 ggtttaaata ctcgtgcagg tgctatagta ggacatttag ctcatgattt taatccaaga
    15061 gatgttggtg cttggtctaa tgtaagaaat tctgtagcca aaggtactat tgatgttgct
    15121 agaggtgatg taggcggttt aattggtaaa gactggcctt ggggaaccat tgataacaat
    15181 atcagcttag tgaatgttaa gcgtggtgat attttctttg gttctaatga tatggatgat
    15241 gaatttgtaa gcaattggat taaacctaat aatgcaacag ttatcggtgt gagttctgga
    15301 gataaaaccc ataaacaatc gtctaaaatt aaagaaattt cacaggtaga agctgataag
    15361 aaaattaagg atatgggtat cactgctgat acatttgaag taactgagca tttggttgat
    15421 aagttgaatc gccgtatatt acgtgatgaa gaatacaaaa caattcaaga ttataatgca
    15481 aatcgtgagc ttgtttatcg taatgttgaa aaactccaac cgttctacaa caaagaatgg
    15541 attgtgaatc aagggaacaa acttacaact gatagtccat taatgaataa agaagtattg
    15601 tctgtgactg caatgaaagg taatgacttt attacagacc ttacagatgc tgaccatatt
    15661 atggttcatt acgcagataa gacaaaagat atctttacga tttctcctaa agactctcaa
    15721 gttaagcaag taaaagaata cagtgtcgca gagcttggtg aagtcgtcta tacaccaaat
    15781 atggttgtta aagatcgtgc agatttaatt agtgctattg aaggtatttt aagtccaatt
    15841 gaattacaat ctgatccaat ttatcaacga ttaggaagaa ctggggataa cagagttaat
    15901 gcaattaaga atctttactt agaagaaagc tttaaagaag taaaagatca tcttaataca
    15961 tttgtgacaa aattagttga aaatgaagat catcaactga atacagatga agctgcaaaa
    16021 cgtgccttga ttaagaaaat tgaagataac aaagctgctg tcctgttagg attaacatac
    16081 ctaaatcgtt attacggtgt gaaatttgat aacttcaata ttaaagaatt aatgctattc
    16141 aaaccagatt tttatggtaa gaatgtaagt gttttagatc gattaataga aattggttca
    16201 aaagaggact atattaaggg aagtcgtaca caggagtcct tccgtgaagt ggtggcgaaa
    16261 aatactcttt ctggaaactt acatgacttc ttgacctaca atatgaaact attcacaaat
    16321 gaaacagaca taaatgtttg gtttaagaaa gctattgaaa ataatgctta tgtagttgaa
    16381 caaccgtcaa ctaaccctgc atttgctaat aaaaaatatc gtctatatga aggacttaat
    16441 aacggacaac atggacgcat gattttatcg cttctgaact tgaaagatgc acatttattt
    16501 atgatttcaa catataatac tatctcattt agttcgtttg aaaagtatgg taaagataca
    16561 gaagaaaaac gtgaaacgtt caagagtgaa atcaataaac gtgctaaaga gcaagttaat
    16621 tacttagatt tttggtcacg ccttgccact gataatgtcc gcgataaact tcttaagagt
    16681 caaaatgtag ttccaactcc tgtatgggat aatcatggtg cacccggtgg ttggcctgat
    16741 agatttggtc atcgaaaaga taaaccggat tatgcaccta ttcgtgaatt ctttggacgt
    16801 attgataagt atcatgatta taagtatggg tatggagcgt atgcttacat ctttgctgat
    16861 ccacagccta tggatgctgt atattttgtt atgtcggatt taataagtga atatggcaca
    16921 tctgccttta cacatgagac tacccacgta aatgaccgaa tggcatatct gggaggtcat
    16981 agacatcgac agggtacaga tcttgaagca tttgctcaag gtatgttaca aactccagca
    17041 gaacatggac atcaaggtga atatggcgca cttggattaa atatggcatt tgaacgttca
    17101 aatgatggaa accaatggta taatccagat cctaccaaac ttcaaacacg tgaccaaatc
    17161 gaccattaca tgaagaacta caatgaagct atgatgatgc tcgattatgc agaagctgag
    17221 gctgttcttc ctaaggttaa aggtgacaat agtaagtggt tcaagaaaat tgatcgcgaa
    17281 acacgtcgac caatggacag aaataaacta agtggtcctc accaatggga caaagtgcgt
    17341 gatttgatag acgctgagaa aacaactaac cttgaaacca tcgatgactt ggtaaataat
    17401 aatttcatga ccattcacgg aaatccaggt aataaggtct tccacccaga ggactttggt
    17461 acggcatatg tcaatgttaa tatgatggct ggtatttatg gcggtaatac gagtcaaggt
    17521 gcccctggtt ctctatcctt caaacataac gccttccgta tgtggggtta ctatggatat
    17581 gaacatgggt tcattgacta tgtttcaagc aaacatcaag gtgcagccaa taaagaaaat
    17641 aacggtctat taggtgatga tttcattatt aagaaagttt ctaataacca attttcaaac
    17701 cttgaagatt ggaagaagca atggtatggg gaagttctta caaaatctaa aaaaggtttt
    17761 gcaccaattg aaattaatgg cactcaaatt tcaacctatg aacagttgaa gactatgttt
    17821 gatgaggctg ttactaaaga tttaacggaa ctaaacgata gtagtattaa agacaaatac
    17881 cgaaatacag ttgtcttgaa atcgaaagtc tttaaagctc tccttaaaaa cacagacggt
    17941 ttctctggtg atctatttac tgcaccacaa gcatagaatg aataaaatcg taaaaaggta
    18001 gatcagcttt gtctgtatct gcctttttat gctatactta aggtatgcat agaaaaacag
    18061 tgattgattt taggactttg ggggagagat atacctttac caagcctatt aaagagttga
    18121 aaacgagaaa tgtagaagaa gtggcagatt tgctggcaca agtggaaagc taccaagagc
    18181 aaggttatta tgtggtgggg tatgtcagct acgaggctgc acctgctttt gaggaaaaat
    18241 tagcagttca caaggatccc ctactgggag agtacctgct ttattttact gttcatgata
    18301 gcgtagaaac ttcccctatt cctctgactt atgaggatat tgatttgccc tcaaattggc
    18361 aggaagtaac gtctgcagca gactatgaaa aggccattgc ccaaattcac catcatttac
    18421 ggcagggaga tacctatcag gtcaactaca ccgtccaact taagcaaaag ttaaatgcca
    18481 atccttttgc catctacaat cgtatggtgg tagagcagga ggcgggctac aatgcctatg
    18541 tggaacatga cgagatggca gtgatttcca tgagcccaga gctctttttt gagcaaaatg
    18601 atcgcgagtt gacaacacga ccaatgaagg ggacgactca gcgtggggta actgaccaag
    18661 aagatcttga acaggccagt tggttggaac aggatcccaa aaatcgctct gaaaatatga
    18721 tgattgtgga cctcttgcgc aatgatatga accgtatttc tgaagttggg agcgagcacg
    18781 tggagcgtct gtgtcaggta gagcagtatt caactgtttg gcagatgact tcgaccatca
    18841 agagtcagtt gcgagaggat gtggaccttg ttgaaatctt ccgctcactc tttccttgtg
    18901 gttccataac gggtgcaccg aaaattgcga caatggagat tatcaaggac ttggagcctc
    18961 aaccgcgtgg agtctactgt ggaacgattg gtctcttgct tccaaatgga cgacggattt
    19021 ttaatgtggc cattcgtacc attcaacttc acaaaggtca agccatttat ggagttggcg
    19081 gagggattac ttgggatagc acatgggaat ctgaataccg agaggttcat caaaaggcag
    19141 cagttcttta tcgtaaacaa gctcgcttcc aactgattac gacaggggaa atcagccaga
    19201 agaacctgtt gtttgaagat caacatctgg aaagactgag aaaagctagt cgttattttg
    19261 cctttccttt tgatgcagaa gacttgggac acaagattga ggaagagtgt caggattgtg
    19321 aagctaatcg agattaccgc ttgcgaatca gccttagcaa atctggagag atagaagtca
    19381 atcgtcaagt attaacccct ctcagtacaa gcttttgtca ggcccaagtc tgccttcagg
    19441 aagctgcttt gaatcaatcc tttacctact ttaaaaccac tcaccgaccg catttgagcc
    19501 taggagaaca agagaagatt taccacaata agtcaggaga actgcttgaa acctctatag
    19561 gaaatttggt tctgaaaatc gctggaaaac tctacacacc gcctatccga cttggaatct
    19621 tgccaggaat ttaccgtcag tatttgctag aaacaggaca ggtagaagag aaagtcttga
    19681 ccttggcaga tttagcccaa gcagaagcta tttacggctg taatgcagtg agaggcttgt
    19741 atgaactaag ccttgaggag aactagatga aactgatatt tttgcatggg ttagggcagt
    19801 cagcagagtc ttggaaagaa gttcggaatc tactgacaga ttatccttct gaggctatcg
    19861 agttatttcc ttctggagtt agtaactatc aacaagctaa ggagcgagtt tatcagcacc
    19921 tagctcaaga gacagaacct tttgttttga ttggattgtc cttaggtgct gccctggcac
    19981 tagaactttc cagttacgat ttaccaaatc ttcgagcttt gattctgtca agatgcccgc
    20041 ttaaattagc agggaatatc ctattttatc ttcagttgct gatttttaaa ctacttccca
    20101 aaagagtatt tgaaaaacag ggagcagaca aggctcttat ggtcggagtt tctgaggagt
    20161 tgaagacact tgatttaacg gatatagcag gaacttgccc ttatccaacc ttactaattt
    20221 gtggtatcaa agataaaccg aatcttagtt ctatgagaag tcttcataaa ctaatatcag
    20281 aatcccaatt tcagattatc ccagatggcc ctcatgtctt gaataaggca aaaccaaagg
    20341 agtttgtaga aaagaccaga agtttccttg aattgctgaa ataagtttga taaaataata
    20401 ttgaaatcga tatcataatt atgggagaaa gaaatgaata aacgtctatt tttaaaaatg
    20461 agtctggtga cgttgccaat tttagccttg ttttcacaac cagttttggc ggaagaaaac
    20521 atccattttt cgagctgtaa ggaagcttgg gcgaatggct attcggatat tcacgaggga
    20581 gaacctggtt attctgccaa gttagaccgt gatcatgatg gtgtggcttg cgaattgaaa
    20641 aatgctccta agggtgcttt taaagcaaaa cagtcaacgg ctattcaaat caacacaagt
    20701 tcagcaacaa caagtggttg ggttaagcag gacggcgctt ggtactactt tgatggaaat
    20761 ggaaatctag tgaaaaatgc atggcaggga agctattacc tgaaagctga tggtaaaatg
    20821 gcccagagtg aatggattta tgactcttct tatcaagctt ggtattattt gaaatcagat
    20881 ggttcttatg caaaaaatgc atggcaagga gcttattacc ttaaatcaaa cggtaaaatg
    20941 gcacaaggtg agtgggttta tgattcttct taccaagcat ggtattactt gaaatcagat
    21001 ggttcatatg ctcgcaatgc atggcaagga aactactatt tgaaatcaga tggtaaaatg
    21061 gctaaaggtg aatgggttta tgatgccacc tatcaagctt ggtattattt gacatcagat
    21121 ggttcttatg cttacagtac atggcaagga aattactatc taaaatcgga tggtaaaatg
    21181 gctgtcaatg aatgggttga tggtggacgt tattatgttg gcgctgacgg agtttggaag
    21241 gaaggtcaag caagtacagt ttcttctagt aatgatagca atagtgaata ttctgctgct
    21301 ttaggaaagg caaaaagtta taattcgtta ttccacatgt caaaaaaacg tatgtataga
    21361 caattaactt ctgattttga taaattttca aatgatgcag ctcaatatgc cattgatcat
    21421 ttagatgatt aacagatact ggtaggcgaa aaaattcctt ataattcatt tacgcaaacc
    21481 tttgcataag tgaatggatt ttgatatact agtactgtaa gcattttcaa ttactacaca
    21541 atgaaaaagg agaatatgat gagtcaaaag attattggga ttgaccttgg tggaacttct
    21601 atcaaatttg caatcttaac aacagcagga gaaatccaag gaaaatggtc aatcaagacc
    21661 aacattttgg atgagggaag tcatatcgtt gatgatatga ttgagtctat tcaacatcgt
    21721 ttggacttgc ttggattggc agcagcggac ttccaaggca ttggaatggg atcaccaggt
    21781 gtggttgacc gtgacaaagg gactgttatc ggtgcctaca acttgaactg gaaaaccctt
    21841 caaccaatca aacaaaagat tgaaaaagct ttgggcattc catttttcat cgataatgat
    21901 gccaacgtag cagctcttgg tgagcgctgg atgggtgctg gagataacca accagacgtt
    21961 gtctttatga cactcggtac tggtgttggt ggcggtatcg tcgcagaagg caaattgctt
    22021 cacggtgttg ctggtgcagc aggtgagctt ggtcacatca ctgttgactt tgaccagcca
    22081 atctcatgta cttgtggtaa aaaaggctgc cttgagacag ttgcttcagc aacagggatt
    22141 gtcaacttga ctcgtcgcta tgccgatgaa tacgaaggcg atgcagcctt gaaacgcttg
    22201 attgataacg gagaagaagt aactgctaag actgtctttg atctcgcaaa agaaggagac
    22261 gaccttgctt tgattgttta ccgtaacttc tcacgttact tgggaatcgc ttgtgctaac
    22321 attggttcaa tcctaaaccc atcaacaatc gtcatcggtg gtggtgtgtc agctgcggga
    22381 gaattccttc tacaaggtgt tcaaaaagtt tacgatgaaa atagtttccc acaagtacgc
    22441 acatctacta aattagctct tgcaactcta ggaaatgacg ctggagttat cggagcagca
    22501 tcacttgtat tgcaataaga taatgagaga ggaaaatgct aacctagagt tagtaatgtt
    22561 cctcttttat tttttatgct atactagtta ggacaatgaa tgaggtgaga gtaaatgaca
    22621 aaagcagata cgatttttaa agagaatatt gaacgcattc taaaggaagg tgttttctca
    22681 gagcaggctc gtcctaagta caaggatggg actgttgcta attccaagta tgtaactggt
    22741 gccttttccg agtacgactt atctaaagga gaatttccta tcacaacctt gcgtcccatt
    22801 gcaatcaaat ccgccatcaa agaagttctc tggatttacc aagaccagtc aaatagctta
    22861 gaagtgctta atgacaagta caatgttcac tactggaatg actgggaagt tggagacacg
    22921 ggaaccattg gtgagcgcta tggtgccgtt gttaagaaac acgacattat caataagctt
    22981 ctcaaacagt tggaaaccaa tccttggaac cgccgcaata ttatttcgct ctgggattac
    23041 caagctttcg aagaaacaga tgggctgctc ccgtgcgcct ttcagaccat gtttgatgtc
    23101 cggcgtgttg atggggaaat ctatctggat gcgaccttga cccagcgctc caatgatatg
    23161 ctggtggccc accacatcaa cgctatgcag tatgtggctt tgcagatgat gattgccaaa
    23221 cattttggct ggaaggttgg gaagttcttc tacttcatca acaacctcca tatctatgat
    23281 aatcaatttg aacaagctca ggaattgctc cgtcgggagc cgtcaaactg ccaaccacgc
    23341 ttggttttaa atgttcctga tgggactaat ttctttgata tcaaagcaga agattttgag
    23401 ttggtggatt atgaccctgt taagccacag ttgaagtttg acctagctat ttaaaagaat
    23461 agaaaaaaga agttgagaat aatcccaact tcttttgttt cttaacgtga tacgcggcga
    23521 cgagctgctt ttttacggtt ttcttcgatg aaagctgctt tttgctcttc tggttcgatt
    23581 actttctttt taaatgcgta tactgcacct gcaacggcag cgacagttcc tgcgacacct
    23641 gttacaagac ctttagcgaa tcctttagcc atgagtcttc ctcctttata ttctcaatca
    23701 gccagcctcc tcaagaggtc acatttttct gactgacctt tttgtgttat aataatagta
    23761 acgaaaaaat gggaattttt caaggaaaaa agatgaaaac aaaaataatt gtgattgttg
    23821 gaccgactgc tgttggaaag acggctctag ctattgaagt tgcaaagcgt tttaatggcg
    23881 aagtggttag tggagatagc cagcaagtct atcgaggact tgatattggg acggccaagg
    23941 ctagtccaga agagcaggca gctgttcctc atcatttaat cgatgttaga gagataaccg
    24001 agtcttactc ggcttttgat tttgtttcag aagctaagat gactattgag ggtattcaca
    24061 accgtggcaa gctagccatt atcgccggtg ggactggact ttatatccag agcttgctag
    24121 aaggttacca cctaggtggg gagactcctc atgaggagat tttagcttat cgagctagtt
    24181 tggagccata ttcagatgag gaattagccc atttggtgga tcaagcaggc cttgagattc
    24241 cccagtttaa tcgtcgtcgt gctatgcgtg ccttagaaat tgcccatttt ggtcaggatt
    24301 tggaaaatca agagaccttg tatgaaccgc tgattatctg cttggatgat gaacgtagtc
    24361 aactttatga gcgtatcaac caccgagtgg atttgatgtt tgaggctggg cttttggatg
    24421 aggccaagtg gctgtttgac cattccccta atgtacaggc tgctaaagga attggctata
    24481 aggaactctt tccttatttc cgtggagagc agaccttgga ggaagctcgt gagagtctca
    24541 aacaggctac tcgtcgtttt gccaagcgtc agctgacctg gttccgtaat cgcatgcagg
    24601 tcacctttta tcagattgga gaatctggtg tacaagaccg cattttaagc cagatagagg
    24661 agtttttaga tgattgaaac ggagaaaaaa gaggagcggg tcctgctgat tggtgtggaa
    24721 ttgcagggta tggacagttt tgacctctcc atggaagaat tggctagttt agcgaaaacg
    24781 gcaggggcag tcgttgtaga tagctacaga caaaaacgtg aaaaatatga ttccaagacc
    24841 ttcgtcggct ctggtaagtt ggaagagatt gcgcttatgg tggatgcaga agaaatcact
    24901 actgtcatcg tcaacaaccg tctgacccca aggcagaatg tcaatctaga ggaagttctc
    24961 ggtgttaagg tcattgaccg tatgcagttg attttggata tctttgccat gcgggctcga
    25021 agccatgaag ggaagctcca agtccaccta gcccaactca aatacctctt gcctcgcttg
    25081 gttggtcagg ggattatgct cagccgtcag gcagggggaa ttggttcccg tggtcctggt
    25141 gaaagccaac tggagctgaa ccgtcgtagc gttcgcaatc aaatcacgga tatcgagcgc
    25201 cagcttaagg tggttgagaa aaatcgtgcg actgtcagag aaaaacgttt ggagtctagc
    25261 acctttaaga ttggtttgat tggttatacc aatgctggga aatcaactat catgaacatc
    25321 ttgaccagta agacccagta tgaagcagat gagctctttg cgactctgga tgcgacaacc
    25381 aagagtattc atctaggagg caatctccaa gtaactttga cagataccgt tggctttatc
    25441 caagatttgc cgacagagtt ggtgtccagt ttcaagtcaa ccttggaaga aagcaagcat
    25501 gtggaccttc tggttcatgt tatcgatgct agcaatcctt accacgagga gcatgaaaaa
    25561 acggttctct ccatcatgaa agacctggac atggaagata ttcctcactt gacgctttat
    25621 aataaagcgg atttggtgga ggatttcacg cctacccaaa cgccatatac cctcatttct
    25681 gccaagtctg aggacagtcg tgaaaacttg caagcattat tgctagataa gattaaggaa
    25741 atttttgaag catttaccct gcgagtgcct ttttcaaagt cctacaagat tcatgattta
    25801 gagagtgttg cgattcttga agaacgtgat tatcaggaag acagcgaagt gattacaggc
    25861 tacatttccg agaaaaataa atggaggtta gaagaatttt atgactgata ttaaaacttt
    25921 ggctctaaag tatggaggtt atacaagtct ggacaaggtc tatctggatc agcttctagc
    25981 tggtaaaaca gagcaggagc agttaacact tattacacct ccgccaagtg ttgttaatgc
    26041 ctactttgca gaactctatc agaaaaagag tcctcaggct gcgacggatt attttgcaga
    26101 actcagtcag gaactgaatc tttacaatac tgagccaagt ttcaccctag aaaataagtc
    26161 ttttattcgg cttaatctgt ctggtaaatc ctttggtttt tgttatgaga gtgacggctt
    26221 tggtcggatt ttctctgaaa atgaggagaa aatctcggat gacttgctct ttgaaattgc
    26281 gcaaattttc ccccatcaat tagtctttga agagtctggt aagatttaca tgaagcctgt
    26341 cgaggacgag gaagttgtca gcctagaaag tctcacagct ttgactgatt tggaaagatt
    26401 ggctgatggt cgaaaacgtc tcaaaggcta cagccaagag gatttattga aagaagctgc
    26461 tgctttttct ggcaaacgct atttccgatc ggaaaaccgc acagccatgt tatatattga
    26521 ttaattagaa agtatcgaat ggatattcaa tttttaggaa cgggggctgg tcagccctct
    26581 aaagcccgca acgtttcaag tctcgccctg aaacttttgg atgagattaa cgaagtttgg
    26641 ctctttgact gtggagaagg tacgcaaaat cgcattctgg aaaccacaat tcgaccacgt
    26701 aaggtcagca aaatctttat tacccatctg catggagacc acatttttgg tttgccaggt
    26761 ttcctttcta gccgtgcctt tcaggccaat gaagagcaga cagatttgga aatctacgga
    26821 cctcaaggaa tcaagtcatt tgtcttaacc agccttcgtg tgtcaggttc tcgtctgccc
    26881 taccgcattc atttccatga gtttgaccaa gattctctgg gtaaaattct tgaaaccgat
    26941 aaattcactg tgtatgcaga ggagctggac cacactattt tctgtgttgg ctatcgtgtc
    27001 atgcaaaagg atctagaagg gacgctggat gctaaaaaac tcaaggctgc tggtgttccg
    27061 ttcggcccgc tttttggtaa aatcaaaaac ggccaggatc ttgttttgga agacggaact
    27121 gaaatcaagg cagcagacta tatctcagcg ccacgtccag gtaagattat cactatttta
    27181 ggagacactc gaaaaacgga tgccagtgtg cgtctggctg tcaatgcaga tgtcctagtt
    27241 catgagtcca cttatggcaa ggatgatgaa aaaattgctc gtaaccatgg tcactcaact
    27301 aatatgcaag ctgcacaagt agcggtagaa gcaggtgcca aacgcctcct actcaaccat
    27361 atcagtgccc gtttcctctc aaaagatata agcaaactca agaaagacgc tgccacaatt
    27421 tttgaaaatg tccatgtggt caaagacttg gaagaagtgg aaatctagca gtcacagaaa
    27481 ggataagtat gcctactatt ctcattaccg gagctagcgg tggtctagct caagaaatgg
    27541 tcaaactcct gcccaatgac caactcatct tgcttggtag aaataaggaa aaattagccc
    27601 aactctacgg aaattattcc catgcagaat tgattgaaat tgatattacc gacgattcag
    27661 ccctagaagc tctggtaact gatctttatc tccgctatgg caagattgat gtcttgatta
    27721 acaacgctgg ttacgggatt tttgagggat ttgaccaaat tgctgataaa gacattcacc
    27781 agatgtttga ggtcaatacc tttgccctga tgaatctgtc tcgtcacctt gcggctcgta
    27841 tgaaggaaag cagcaaaggg catatcatca acatcgtcag catggcaggt ctaatagcta
    27901 ctggcaagtc tagtctttac tcagcgacca agtttgcggc tattggtttt tcaaatgctc
    27961 tgcgactcga acttatgccc tatggagtct atgtgacaac agtcaatcca ggtccaatcc
    28021 gaacaggatt ttttgaccaa gctgacccag atggaactta tcttaaatcg gttgaccgct
    28081 tcctcttaga ggcagatgca gtggctaaaa agattgtcaa gattataggc aaaaataaac
    28141 gagaactcaa tctcccgatt ttgttgaacc tagcccataa gttttatact ctctttccca
    28201 agctagctga taagttggca ggggaaactt ttaattataa gtaaaaagaa ccaatgtgca
    28261 ggttgttgct agcctacata ttggttctta tcatttctca actatcaaac tgaacttctt
    28321 ctagtagata gtcgataaag cgttcgccca tcttagatag gctggttttc tcatgctgga
    28381 tatagaccag ctcaatcggg tcatcaatat ccagtgggat agaaacgata ttgtctccgt
    28441 ttaggttgct gttcaaaatc cctgtcgcaa tggtataacc atccaaacca atcaagagat
    28501 taaagagggt ggcacggtca ctgaccacaa tggatttctt gtggtgttct tgagaaagaa
    28561 tctcttctga aaagtagaag gagttgtgcg tcccttggtc atagctgagg taagggaaat
    28621 tctccaaatc agacagtttc accttgtctt tctttgccag agggttggtc ttgctgacaa
    28681 agatatgcgg ttgcgctgtg aagagatggt gggctagcag gtgattgtca tccagcatct
    28741 tggttaaaac atcacggttg taactgttta agaagaggac cccgacctca ctgcggaagt
    28801 tcttgacgtc gtcgataatc tcccaagtcc gagtttcacg aaggaagagt tcgtatttct
    28861 ccatatcgct tttcttgagc aaagagacaa aggcattgac cacaaaggca tagtgttgag
    28921 acgaaacgct aaagagttcg cggtgggcga caggattttt atagcgttcc tccagaagct
    28981 gggtctgctc gacaacctga cgggcataag agagaaactc catcccatca cgggtcaagg
    29041 tgattccctt gggattgcgg ataaagatct caatgcccat ttcattttcc aaatctcgca
    29101 ctgcattgga gagacttggc tgagtgataa agagttgctt ggctgcctca ttcatggagc
    29161 cagtttcgac gattttgata atataatgta attgttgaat tctcatgttt ttattgtacc
    29221 atacttgcct tagaatcgct aaagaagata ggaaaataag gagcattgtg tgagtctctt
    29281 cttgaaaaaa acacaaaatt ttgctagaat gagtcttatg aaaacattct atgatgtgca
    29341 gcaattcctc aaacgatttg gtattattgt ttacatggga aaacgcttat atgatattga
    29401 actgatgaag ttggaactat ctcggattta cgatgcaggg ttgatggata aattagacta
    29461 tctagaggca gaagcagttc ttcgcagaga gcacaaggta gaattggatt atattgagaa
    29521 aaatggagaa aagaactaat ggttacttgg attttgtggg cacttatact agcaatgttg
    29581 gcgtggatgg gctttaacta tcttcgtatt cgccgtgcgg ctaaaattgt ggacaatgag
    29641 gagtttgaag ccttgattcg tacgggtcaa ttgattgatt tgcgcgaccc agcagaattc
    29701 cacagaaaac atatccttgg tgcacgcaat attccttcaa gtcagttgaa aactagtctt
    29761 gcagcccttc gtaaagataa acctgtcctt ctctacgaaa accaacgtgc gcaacgagtt
    29821 acaaatgcag ctctttactt gaaaaaacaa ggtttttctg agatttatat cctttcttat
    29881 ggcttggatt cttggaaagg gaaagtgaag actagctaac cttatttcca aattagtcga
    29941 atgataggat gaagatattg ttttatagta taattaattt gtataaaatt taaggagttc
    30001 ttagaacatg aaagaaaaga agaaaaatcc actttttgtg ggtatcttgt cgattattct
    30061 tggtttgtta tttccaattg taggcctgat tttgggtatc ataggattgg tcttggctat
    30121 ttcataccaa aaagagtcac aattagacta taaaatagaa aagattctta atatcttagg
    30181 aattgtgatt tctgtagtta actggattgt agcaatcgcc ttaatttttc ggtaaataaa
    30241 agaaaaaagc tttagtttta aagctttttt tgttttatcg actcatctct aaatagtttt
    30301 taatgatttg taactctttt tggttcaaag ggcggtagtt accttctgct aaatctgggt
    30361 tcaatgtgaa gtccccaaat tggattcttt tgaggctagt caccttaaca ccaaccgaga
    30421 ggaacatttt cttgatttga tgaaattttc cttctgaaat ggtgatagag gcttgactga
    30481 gggagggact tgcagataga atctctagtt ttgcgggttt acagacagta ccatctaaaa
    30541 agacaattcc cttttgaaag gcttggatat ggtcaggtgt tagaagtcca ttaacctgga
    30601 cttggtaagt cttatcgaca tgatattggg gatggaggag ctgaaagccc aagggaccgt
    30661 tatcggtcaa gaggaggagt cccgttgtat ctcggtccag tcggccaacg gcatagagct
    30721 tgtcagactg gatgtcagat ggaagcaggt ccatgacggt cggaagttcc ttgtctttgt
    30781 tggctgtaac gacaccagca ggtttatgaa gcataagata ggtgtgttca tagccttgaa
    30841 tgattcgatc ctgaaaaagg agttcttgta gtcctgtatc gatattttga gctagggagc
    30901 gggctgggca accatcgact agaatttccc ctctgaggag tgcttgcttc atggcctttc
    30961 ggctaacttt ttcttgggct aataaattat ctaaacgcat actgtgccta tcttatcata
    31021 agtcgcttgc tttgaaaagg cttgacgtga aaagaaaagc ggagtgaaaa catttacact
    31081 tgcttgagtt atgttattta cttgaaatta tggtataatc gttcagttag aaaataaatt
    31141 ttgaatatta tagaggaaat catgacaaaa ttaagagaag atatccgtaa cattgcgatt
    31201 atcgcccacg ttgaccacgg taaaacaacc ctggttgacg aattattgaa acaatcagaa
    31261 acgcttgatg cacggactga attggcagag cgtgctatgg actcaaacga tatcgaaaaa
    31321 gagcgtggaa ttaccatcct tgctaaaaat actgccgttg cttacaacgg aactcgtatc
    31381 aatattatgg acacaccagg acacgcggac tttggtggag aagttgagcg tatcatgaaa
    31441 atggttgacg gtgttgtctt ggtcgtagat gcctatgaag gaaccatgcc acaaactcgt
    31501 ttcgtattga aaaaagcctt ggaacaagac cttgtcccaa tcgtggttgt taacaaaatc
    31561 gataagccat cagctcgtcc agcagaagta gtggatgaag tcttggaact tttcatcgag
    31621 cttggtgcag atgacgacca gcttgatttc ccagtggttt atgcttcagc gatcaacgga
    31681 acttcttcat tgtcagatga tccagctgac caagaagcga ctatggcacc aatctttgac
    31741 acgattatcg accatatccc agctccagta gataactcag atgagccttt gcagttccaa
    31801 gtgtcacttt tggactacaa tgacttcgtt ggacgtatcg gtatcggtcg tgtcttccgt
    31861 ggtacagtta aggttgggga ccaagttacc ctttctaaac ttgacggtac aactaaaaac
    31921 ttccgtgtta caaaactctt cggtttcttt ggtttggaac gtcgtgaaat ccaagaagcc
    31981 aaagcgggtg acttgattgc cgtttcaggt atggaagaca tctttgtcgg tgaaaccatc
    32041 actccgacag atgcagtaga agctcttcca atcctacaca tcgatgagcc aactcttcaa
    32101 atgactttct tggtcaacaa ctcaccattt gctggtaaag aaggtaaatg ggtaacttct
    32161 cgtaaggtgg aagaacgctt gcaggcagaa ttgcaaacag acgtttccct tcgtgttgac
    32221 tcaactgatt caccagataa atggactgtt tcaggacgtg gagaattgca cttgtcaatc
    32281 cttatcgaaa caatgcgtcg tgagggctat gaacttcaag tatctcgtcc agaagttatc
    32341 gtaaaagaaa tcgacggtgt taaatgtgaa ccatttgaac gtgtacaaat cgacactcca
    32401 gaagaatacc aagggtctgt tatccaaagc ctttctgaac gtaaaggtga aatgttggat
    32461 atgatttcaa ctggtaatgg tcaaactcgt ttggtcttcc ttgttccagc gcgtggtttg
    32521 attggatact caactgagtt cttgtcaatg actcgtggtt acggtatcat gaaccatacc
    32581 ttcgaccaat acttgccatt gattccaggg gaaattggtg gacgtcaccg tggtgccctt
    32641 gtttctatcg atgctggtaa ggctacaact tactcaatca tgtctatcga agaacgtggt
    32701 acgatctttg tcaacccagg tactgaggtt tatgaaggaa tgatcatcgg tgaaaactct
    32761 cgtgaaaatg acttgacagt taacatcacg aaggcaaaac aaatgaccaa cgttcgttca
    32821 gctactaagg accaaacagc tgttatcaag acgcctcgta tcttgacact tgaagagtct
    32881 cttgagttct tgaacgacga tgagtacatg gaagtaacgc ctgagtctat ccgtttgcgt
    32941 aaacaaatcc ttaacaaagc agagcgtgag aaagctaaca agaagaaaaa atcagctgaa
    33001 taagagctag aaagagagaa agatggtcta tttagtccta ggaattttac tgctcctact
    33061 ctatgtattt gcgacaccag aaagcattaa agggactgtc aatatcgtcg ctatggtatg
    33121 tattttagtg gcactcttga ttttattggt tctatctttt ctgaaaattt ttcaattacc
    33181 aacagaaata ttcctagcaa tagccatgtt gatcctagct tactttagtg ttagagacat
    33241 cacactcatg ccagtcaaaa aaagtaaaag aagataaaaa gagagttttg gctctctttt
    33301 ttgctaggaa ttttacaaga ttgcaattta tttttgagtt atcaccatct cttttgtttg
    33361 gataatatga atgggaaaaa cttgaataaa attctttaat ggcatctatt ttatatttgg
    33421 ttagtactgg ttgcatatta ttttga
//
LOCUS       DBJKQU010000020        33089 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.020, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000020 DBJKQU010000000
VERSION     DBJKQU010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33089
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.020"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(196..393)
                     /gene="blpI"
                     /locus_tag="ACSUUC_001046"
     CDS             complement(196..393)
                     /gene="blpI"
                     /locus_tag="ACSUUC_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HHQ8054271.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            683..1270
                     /locus_tag="ACSUUC_001047"
     CDS             683..1270
                     /locus_tag="ACSUUC_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HHQ8054272.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            1197..2840
                     /locus_tag="ACSUUC_001048"
     CDS             1197..2840
                     /locus_tag="ACSUUC_001048"
                     /inference="COORDINATES: protein motif:HMM:TIGR01193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HHQ8054273.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDVLASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2851..4212
                     /locus_tag="ACSUUC_001049"
     CDS             2851..4212
                     /locus_tag="ACSUUC_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HHQ8054274.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANYLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLGNNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            4269..4424
                     /gene="blpC"
                     /locus_tag="ACSUUC_001050"
     CDS             4269..4424
                     /gene="blpC"
                     /locus_tag="ACSUUC_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HHQ8054275.1"
                     /translation="MDKKQNLASFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(4469..5809)
                     /locus_tag="ACSUUC_001051"
     CDS             complement(4469..5809)
                     /locus_tag="ACSUUC_001051"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHQ8054276.1"
                     /translation="MNIVWILLHTLITNGLEIVIFFKVDGINLTFERIFKAFLLKILL
                     VFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDIERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(5823..6560)
                     /locus_tag="ACSUUC_001052"
     CDS             complement(5823..6560)
                     /locus_tag="ACSUUC_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHQ8054277.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETDLLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6565..6903)
                     /locus_tag="ACSUUC_001053"
     CDS             complement(6565..6903)
                     /locus_tag="ACSUUC_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HHQ8054278.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNI
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7179..7508
                     /locus_tag="ACSUUC_001054"
     CDS             7179..7508
                     /locus_tag="ACSUUC_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HHQ8054279.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7676..8725)
                     /locus_tag="ACSUUC_001055"
     CDS             complement(7676..8725)
                     /locus_tag="ACSUUC_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8054280.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFCQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8722..9453)
                     /locus_tag="ACSUUC_001056"
     CDS             complement(8722..9453)
                     /locus_tag="ACSUUC_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054281.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9521..9931
                     /locus_tag="ACSUUC_001057"
     CDS             9521..9931
                     /locus_tag="ACSUUC_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HHQ8054282.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9941..10228
                     /locus_tag="ACSUUC_001058"
     CDS             9941..10228
                     /locus_tag="ACSUUC_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054283.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(10951..12087)
                     /gene="dnaJ"
                     /locus_tag="ACSUUC_001059"
     CDS             complement(10951..12087)
                     /gene="dnaJ"
                     /locus_tag="ACSUUC_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HHQ8054284.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12489..12845)
                     /locus_tag="ACSUUC_001060"
     CDS             complement(12489..12845)
                     /locus_tag="ACSUUC_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HHQ8054285.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(12847..14670)
                     /gene="dnaK"
                     /locus_tag="ACSUUC_001061"
     CDS             complement(12847..14670)
                     /gene="dnaK"
                     /locus_tag="ACSUUC_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HHQ8054286.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15150..15674)
                     /gene="grpE"
                     /locus_tag="ACSUUC_001062"
     CDS             complement(15150..15674)
                     /gene="grpE"
                     /locus_tag="ACSUUC_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HHQ8054287.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15701..16735)
                     /gene="hrcA"
                     /locus_tag="ACSUUC_001063"
     CDS             complement(15701..16735)
                     /gene="hrcA"
                     /locus_tag="ACSUUC_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HHQ8054288.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16899..17409)
                     /locus_tag="ACSUUC_001064"
                     /pseudo
     CDS             complement(16899..17409)
                     /locus_tag="ACSUUC_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
     gene            18017..20350
                     /gene="hsdR"
                     /locus_tag="ACSUUC_001065"
     CDS             18017..20350
                     /gene="hsdR"
                     /locus_tag="ACSUUC_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HHQ8054289.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKAHRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20363..21880
                     /locus_tag="ACSUUC_001066"
     CDS             20363..21880
                     /locus_tag="ACSUUC_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HHQ8054290.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINAIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTNDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILPLDQGFKNRQAQTKQSPSSFIEII"
     gene            complement(21969..22118)
                     /locus_tag="ACSUUC_001067"
     CDS             complement(21969..22118)
                     /locus_tag="ACSUUC_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HHQ8054291.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFYKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            22083..22202
                     /locus_tag="ACSUUC_001068"
     CDS             22083..22202
                     /locus_tag="ACSUUC_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HHQ8054292.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(22298..23644)
                     /gene="glnA"
                     /locus_tag="ACSUUC_001069"
     CDS             complement(22298..23644)
                     /gene="glnA"
                     /locus_tag="ACSUUC_001069"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HHQ8054293.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(23681..24037)
                     /gene="glnR"
                     /locus_tag="ACSUUC_001070"
     CDS             complement(23681..24037)
                     /gene="glnR"
                     /locus_tag="ACSUUC_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HHQ8054294.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(24114..24641)
                     /locus_tag="ACSUUC_001071"
     CDS             complement(24114..24641)
                     /locus_tag="ACSUUC_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HHQ8054295.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDKSVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(24777..25973)
                     /locus_tag="ACSUUC_001072"
     CDS             complement(24777..25973)
                     /locus_tag="ACSUUC_001072"
                     /EC_number="2.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HHQ8054296.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(26063..31003)
                     /locus_tag="ACSUUC_001073"
     CDS             complement(26063..31003)
                     /locus_tag="ACSUUC_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033925 - mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HHQ8054297.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANPELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETAEAASAAKPEEK
                     ASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFALSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDNLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEAQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKSAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            31296..32927
                     /locus_tag="ACSUUC_001074"
     CDS             31296..32927
                     /locus_tag="ACSUUC_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HHQ8054298.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGFGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
BASE COUNT        10070 a         6905 c         6070 g        10044 t
ORIGIN      
        1 tagttaagtt ttttattcct accaatccat caactaagta aagcatcaac gattacataa
       61 acgattgata atataattaa aattttgcta actatcttat tctcatcatt cttagataac
      121 tttgatattt tgtaagtaag taaataagac agtaaattaa tagcgataat aatactatat
      181 ttaagaatca taatcttaca aagaggacat aattcctgaa cctacacaaa taagtgttgc
      241 tgctccccca gttatcggac cagtcgcagc agctaatagt actgctccaa tacaaccacc
      301 gattgcagat cctaaattgc ctcttcctcc actaactatt tcgagttctt cattatccat
      361 aacagaaaat tgttccatca tttttgtatt catgacaaat actccttttt tatttttgtc
      421 ttgttgtaac tttgataagt ttagtatatc atcgtttttt aaaatttttc atccagatct
      481 tgaattgtca tcgaaacgtc ttgaattagc ttttttattt caagccacct ctatttcaag
      541 ccacctctaa atgtttaaaa aaaataattt ctaatcactt ttttaccatt caggaagttt
      601 taatgactat tcaagatttc ataaaatatg aacttagttt tatgacataa tagacctatc
      661 cactatatga aaggaattgc caatgacttc ttataaacgt acatttgttc ctcaaataga
      721 tgcgagagac tgtggtgtcg ctgccttagc ctcgattgct aaattctatg gttcagattt
      781 ttctctagct cacttgagag aacttgcaaa gaccaataaa gaagggacga ctgctcttgg
      841 cattgtaaaa gccgctgatg aaatgggctt tgaaacaaga cctgttcaag cagataaaac
      901 gctctttgac atgagtgatg tcccctatcc atttatcgtt cacgttaaca aagaaggaaa
      961 actccaacat tactatgttg tctatcaaac aaagaaagac tatctgatta ttggtgatcc
     1021 tgacccttct gtaaaaatca ctaaaatgtc aaaagaacgc tttttctatg aatggactgg
     1081 agtagctatt tttctagcta ccaaacccag ctatcaaccc cataaagata aaaagaatgg
     1141 tctactaagc aagcttcctt cctctgattt tcaaacaaaa atctctcatt gcttacattg
     1201 ttctctcaag cttattggtc actattatca atataggtgg ttcttactat ctccaaggaa
     1261 tcttggatga atacattcca aatcagatga aatcaacttt aggaatcatc tcagttggtc
     1321 tggttatcac ctatatcctc caacaagtca tgagcttctc cagagattat ctcctaaccg
     1381 ttctgagcca gagattaagc attgatgtga ttttatccta tattcgccat atttttgaac
     1441 ttcccatgtc tttctttgcg acacgtcgta caggagaaat catttcacgg ttcacagatg
     1501 ctaactctat tatagatgtc ttggcttcta ccattctttc tctttttctg gatgtttcta
     1561 ttctgattct tgtaggggga gtcttgctgg cacaaaaccc taatctcttc ctcctttctc
     1621 ttctttccat tcctatatac atgttcatca tcttttcttt tatgaaacct tttgaaaaaa
     1681 tgaaccatga tgtcatgcaa agtaattcta tggttagctc tgccattatc gaagatatca
     1741 acgggattga aactataaag tcgctcacga gtgaagaaaa tcgctatcaa aatatagaca
     1801 gcgaatttgt agattatttg gaaaaatcct ttaagctcag taaatattct attttacaaa
     1861 cgagtttaaa gcagggaaca aaattagttc tgaatatcct tatcctatgg tttggcgctc
     1921 aattagtcat gtcgagtaaa atttctatcg gtcagctgat tacctttaac acactttttt
     1981 cttactttac aactcctatg gaaaatatta tcaacctcca aaccaaactc caatctgcga
     2041 aggtcgctaa taaccgtttg aacgaagtct atctagtcga atctgaattt caagttcaag
     2101 aaaaccctgt tcattcacat tttttgatgg gcgatattga atttgatgac ctttcttata
     2161 agtatggttt tggacgagat accttaacag atattaatct cacgattaaa caaggagata
     2221 aggttagcct agttggagtt agtggttctg gtaaaacaac tttagccaaa atgattgtca
     2281 atttctttaa accctacaaa gggcatattt ccatcaatca tcaggatatt aaaaacattg
     2341 ataaaaaagt cttgcgccgt catattaatt acctacccca acaagcctat atctttaatg
     2401 gctctatttt ggaaaactta accttgggcg gtaatcatat gattagccaa gaagatattc
     2461 taaaagctta tgaattagct gaaattcgtc aagacattga aagaatgcct atgggctatc
     2521 aaactcagct ctctgatgga gctggtctat caggaggaca aaagcaacga atcgctctcg
     2581 ctcgtgctct tttaactaaa gctcctgttt taatactaga tgaagctact agcggtcttg
     2641 atgtcttgac tgagaaaaag gttatagata atcttatatc cctaactgat aaaaccattc
     2701 tctttgtagc ccatcgtctc agtatagccg aacgaaccaa ccgtgtcatt gttcttgacc
     2761 aggggaaaat cattgaagtt ggtagtcacc aagagttaat gcaggcgcaa ggcttctacc
     2821 atcatctatt caataaataa ggagaatgtc atgaatccta atctttttag aagcgtcgag
     2881 ttttatcaga gacgttacca taactatgcg acagtgttaa ttatacctct ttcattactg
     2941 tttactttca tcttgatttt ctcccttgtt gccacaaaag aaattactgt tacttcccaa
     3001 ggagaaatcg cccctacaag tgtcattgca tctattcagt cgaccagtga taatcctatc
     3061 cttgctaatt atttagtggc aaatcaagta gttgagaaag gtgacttact catcaaatac
     3121 tctgaaacaa tggaagaaag tcagaaaact gccttagcaa ctcaattaca aagacttgag
     3181 aagcaaaaag aaggacttgg aattttgaaa caaagcttag aaaaagcgac tgatcttttt
     3241 tctggcgagg atgaatttgg ctaccataat acctttatga attttactaa acaatcccat
     3301 gatattgaac tgggtatcac aaagactaac actgaagttt caaatcaagc caatcttgcc
     3361 aatagcagtt catcagctat tgaacaagaa attacaaaag ttcaacaaca aattggagaa
     3421 tatcaagagc tgagagatgc tatcataaat aacagagcac gcttaccaac tagcaatcca
     3481 caccagtcaa ttttgaatcg ttatcttgta gcctcacaag gacaaacaca aggaacggca
     3541 gaggagccat ttttatctca aattaatcaa agtattgcag gtctggaatc atctatcgca
     3601 agcctcaaaa ttcagcaagc tggtatcgga agtgtagcaa cttatgataa tagtttagca
     3661 accaaaattg aagtactccg cactcaattt ttacaaacag cttctcagca acaactaacc
     3721 gtggagaatc aattaacaga attaaaagta caactagatc aagcaacgca gcgcttagga
     3781 aacaatacct taaccgctcc aagtaaaggt atcgttcatc tgaacagcga atttgaaggt
     3841 aaaaatagaa ttccaactgg tacagaaatt gctcaaatat tccctgtcat cacagataca
     3901 agagaagtac taatcactta ctacgtatct tctgactatc tacctctact agataaagga
     3961 caaactgtaa gattaaaact ggagaagatt ggaaatcacg gcaccaccat catcggccaa
     4021 cttcagacaa ttgatcaaac tcctaccaga acagagcaag gtaatctctt taaattaacc
     4081 gctcttgcaa aactatctaa tgaggatagt aaactcatcc aatatggctt acaaggtcgc
     4141 gtcactagtg taactgcaaa gaaaacatat tttgattatt tcaaagataa aattttaacc
     4201 cattctgatt aattttcaga taacactcta taactattta ttatcttatc aaaaaggaga
     4261 atcataacat ggataagaaa caaaacctag cttcatttca agaactaaca actaccgaac
     4321 tcaaccaaat tacaggtgga ggactgtggg aagatatctt atacagcctt aatataatta
     4381 agcataacaa tacgaaagga cttcatcatc caatacaact ataaaaaata agaccgagta
     4441 acaagaactc tcggtcttat ttttttcatc attctgtagg tatcatagta agcacctgac
     4501 gaaagacttg atcttgacag gtagtattta aactggcatt gggataactt tccacaatct
     4561 tcataacggt atagagaccg acacctctct cctccccttt agaactaact ccaaaggaga
     4621 agatttcaga aatatcgatg ccctcttctt tgatggaatt ttcgatgatg aaggtctcct
     4681 gtgctccact ttttaaaaag gcaattgaaa catgaggttg accggcctct gcactcgctt
     4741 caatagcatt atcacaaagg atagacacaa tggttagaaa atcaagcagt ctcatcccct
     4801 caacctgaat ctcttcagga acttcgacat taaagacaat gttcttatct ctagctttta
     4861 taaattttcc agctaggaga cttttgaggg cacgatcccg aacattcacc aatcggccaa
     4921 ggtcatattt attgtcctgc aattttttac tagaatcctt taagaccaag tcatagacct
     4981 cttttatctg ctccatatcc tcctcttcaa tacccagacg taaacttgtc aagaggttgg
     5041 tgtagtcatg gcgaaaactc cttacttcct tgtaaagttc ctctatatgc cgactatagc
     5101 gttctatatc tctatagcgc aagacctgct cttggtccag tctatcatgg agtttgtcct
     5161 tcaaataggt atccaatttc ttgataaccc ccataaaaaa taggaggtag aacactagga
     5221 tgagatggcg aacagtcgtt gattgaatac cttgctcata ttcaaagtaa gacagacttt
     5281 gtatcaccaa atagtaagcc cccattatcc agttaatctt agtcagggac ttttgaaaac
     5341 ctgtatctag aatctccctt ctcaaactag taaaatcata gtccaaccat ttcaaaaagg
     5401 ctagagaaat gaagaaattg aaaattatta tacataaccc agtgaatgag tagccatcat
     5461 atacttgccc ttgtcccaaa aatggaagca caaaatagga gactcctcta taaaagagat
     5521 tcaccaatat cattggaaag agaccataaa agaaaaggag ttttttagga agccctctta
     5581 acaataagaa agacaagcct atgccgtaca agggttccat aaaataagat aggtaaacat
     5641 ttcctactat atagctaatc attacaaaaa caaagaccaa cagtatcttc aaaagaaagg
     5701 ccttaaaaat cctctcgaaa gtaagattaa ttccatccac cttaaagaaa atgacaattt
     5761 ctagcccatt agtaataagt gtatgcaata atatccaaac aatattcata aactctccta
     5821 gttcagtgta agttattaat agcctcagac acttccctga ccttataacg cgcgatcaga
     5881 caacttccac cattgggaaa aaaaaggagt ttttctttct tatccaaatg caccacattt
     5941 gcaggattga tgagaaaaga gcgatggcac tgcaagagac ggggttcctg cttgaaaacc
     6001 tcctctaaac tcgctgtaaa ttccagcctg tctgtcttgg tatagagaat aacacgatgg
     6061 gctctgggag acgtttcgag atagtaaacc tctttaaaag gatattggaa ttgggcaaat
     6121 tttgatttaa agtaaaagca atcttccgcc agacttttac tatcttgact attggcatag
     6181 aggaggtctg tctcgattcg agattcaaac tcctctgccg aaagggcctt atcaatatag
     6241 tccagagcag acacttggta gcgaaaggac aggggcataa actccgagtg agtcgtcaca
     6301 aagacaatca gggcataagg atcccgatcc cgaatctttc tagccacttc cagtcccttc
     6361 atctcttcat ttcgaatctc aatatccaaa aagaatagct gatgggcccc cttctcatgc
     6421 acttcagcca gcagttggtc cggcttgcca aatacctcaa aagagctagg aatgatatga
     6481 tgtgctttca aaagtttctc aatcgtcgtt tcaattctag tctgttggga aaaatcatcc
     6541 tctaaaacaa atattctcat cttcttactc tccctctttc aaccattttt gacgaatttc
     6601 tctatagcga cgtctggcat acttgacagc gtattgacct tcttctccga gaaaaaggat
     6661 tctttcttga aaatcaatcg attttaattt atcaagatta accaaacaat ttcgatgaca
     6721 tctcatcaag gtttccccac attggttctc aagattactt aaattttgaa gtatattaaa
     6781 actagcttct tctgtaacaa tctgtacggt atgggcttta gttggatgtg tttggatata
     6841 gtagatatcg tcgatgttta ctttatagac tgttttctgc gtctgaataa tcatatattt
     6901 cattggattc tcctcctaag aaaagaataa cagaaaaggt ctagcccaag cacacccaat
     6961 cctaaacagt ctttgaaaac tcctaaaagg attattttct acaacatcat gatgagctta
     7021 caactatttt atcataaaat tcactcagcg caattcaaga catttcaatg acaattaaag
     7081 atttgaataa aaaaaaagaa ttaaaagtga taaactaaca gtatcaaaac acagttgcca
     7141 gaagtaagac tggcacccag attaaaggag gcattcccat gacagataca gaccccatca
     7201 aaagagctca tactttgatt actgacttaa acaaagccta ccaagcatgc aaacaggcaa
     7261 gcgctgacga cgtccgcttt caggagcaat taaactctat tcttggtttt ctagccaagg
     7321 ctgaaacagt ggataatcga ttcttgattg aactagaaaa attttaccag acttccagtc
     7381 ttctcatggg actcagcgct cttgatccag atgctccaac tcgcgccgct tggcgggcct
     7441 atgaccgctt ccactttgac caagtcaaga ccaagttaat actcaatgaa aatcaaagag
     7501 caaactagga agctagccgc aagctgtact tgagtacggt aagacgacgc tgacgtggtt
     7561 tgaagatatt ttcgaagagt ataagtctct acggaccaac cattatcctg tagtaacaaa
     7621 aaagaagttg agacagactg aactcaactt cttttttagt gtcgtatcag caatgttagt
     7681 cctgcatctg acgttttacc tgataaggca aatacaagac tagtaaaacc aaaccagctc
     7741 ctagtaaggc tagaagggct agtttttctt ggaaggtaat caacccaaca actaattcca
     7801 caagtaaaac aaaactggtc aatcctcgaa ctacctcctg taagcctttt tccttttgcc
     7861 ccttgtccag cggaaagagt tgggtcaaat actggtagtc aaaggcatga tagagggcca
     7921 gcaactggaa gagcaagagg tagttaaaga gaactaccac tgctgtcgca atccaagctt
     7981 gctcgataaa aacctgcgcc agtacggaaa gtaagagaag acgaagactg agagcaaaga
     8041 ggtcgccatt tcgcagataa gaacgcagat agagattttg ccaaatcttc ccaggcacct
     8101 tctgaacagc ctttaaaata aagtccagat aggcacgacg cttaacgctg tttgaaattc
     8161 ccttgacctg cgtaaagagg gcaaagaaac gaagcaagac ttgcttacgc ttgctttctt
     8221 gagaaataag atagtcccag tccagtccag tttcagtgaa aaatttgctg gccttttgac
     8281 aaaagtggaa atattttcct acccccaata aaagcacata gagcagaaaa actggcaagc
     8341 cataacccat tgccaaaaat aaaggcgcaa ataacagcaa gaaaagggtc tgtacaaaga
     8401 gccaaaagac tagggaaatg ccagtttgac gcttgagatg gagcttgatt tcctcttctc
     8461 caactaagag aaagagcttg tctggagcct ccatataggt ggcaattcct ccccaaagta
     8521 aaagtaaaac agacgtaatt cctacaaaca aaaggatagg ccaatgattt tcaggaaaat
     8581 gttgtaagag ttgactgtac tggtaggcta gaaagcccaa caggacaagc aggaacaaga
     8641 caaagtggtc attgagcaca tagcgcagat aaccaagaca ctccttacga aaggcctgct
     8701 ttctctttaa aaacaagtct ttcataggtc ctcctctttt gtcagagcca agtaaatatc
     8761 attcaaacta gcctcaggca tatcaaaggc ttcgcgtagt tgcaggagat tgcctttggc
     8821 acgcacctct cccttgtgaa gaatgacaaa ggcatcacac atcttctccg ccgaatccag
     8881 cacgtgggta ctcatgagaa tagacttgcc cttttgcttc tccacttcca aaagctgaat
     8941 caaatcagaa atagccagcg gatcaagacc aaggaaaggc tcatccacga tgaaaaggct
     9001 tggatccacc acaaaagcac agataatcat gaccttctgc ttcatccctt ttgaaaaatg
     9061 aacagggaac cagtctaatt tctggtccag acggaacatc tttaacaagg gctctactcg
     9121 ttcgaaagcc actttttgct caataccgta agccatagca accgtttcga tatgctctct
     9181 gagggtcaat tcctcataca gactaggcgt ctcaggaatg tagccaatct gcttgcggta
     9241 gctagtcgca tctccttgca gagtcaggcc attgatattg atggagccac tataaggtgc
     9301 caacagaccg ataatctcat tgatcgtcgt tgatttccca gcaccattga gaccaatcaa
     9361 accgaccaac tgcccacttt caacagtaaa ggacacatct ttcaaaacag gaacatgaac
     9421 atagccacct gtcaggtttt taatttctaa catattttct ccaaatctgg tataatgtag
     9481 ctatattata tcaaaattta gtacagtaga ggtagatttt atgtcagatt gcattttttg
     9541 taaaatcatc gcaggggaaa ttcctgcttc aaaagtatat gaagatgagc aggtccttgc
     9601 ctttcttgat atctctcaag taacactagg acacaccttg gtcgtgccaa aagaacacta
     9661 tcgcaatctt ttggagatgg atgctacgag cgccagccaa ctctttgccc aagtaccaaa
     9721 agtagctcaa aaagtcatga aagtcactaa ggctgctggt atgaatatca tttccaactg
     9781 tgaagaagtc gctggtcaaa cagtttttca tactcacgtt caccttgtgc ctcgctacag
     9841 tgctgacgat gacctcaaga ttgattttat cgcccacgaa ccagactttg acaaacttgc
     9901 tcaagtcgct gaaaccatca aaaacgctta aggagttgct atgaaattat ccaacctact
     9961 gctatttgca ggagctgcag ccggaagtta tctggttaca aaaaatcgcc aaaccatcac
    10021 agatgaagtc ttgaatacca ctgaccgcgt tcaagctatc aaggacgatg tggatattat
    10081 ccaaaacagc ctgcaaatca ttaaccagca aaaagaactt atcaaggaat accaagaaga
    10141 cttgacttac aagtttaagg tcttggaaaa ggatatccag actagactag ctgtgataaa
    10201 agaaatgcag ggaactgaag ataagtaaaa agagcccccc ggctcttttt taaaacgtaa
    10261 acaagttata gtgaattgaa tttagaatag cacaccatag tttctaaagc attgttagag
    10321 attactttaa aatcctctta tcaatttgtt catattctat ttcaatctat tatatatatc
    10381 ccatcaacta tgcatcataa tttaggtaac tcatactcaa taaaaatcaa aaagcaaact
    10441 agaaagctag gcacagactg ctcaaaacac cgttttaagg ttgtggatag aactgacgaa
    10501 gtcagctcaa aacactgttt tgaggttgtg gatagaactg acgaagtcag taaccatacc
    10561 catggcaagc cgacgctgac gtggtttgaa gaaatttttg aagagtatca ttcaccattt
    10621 cacaactaaa tcgaagactt tctgccgtaa tgaaaacacc tgaaacagct tggtttcagc
    10681 tgtccggaaa ctttaagact taggttcaaa gtttaggtat ggaacttcga aggaggtcgc
    10741 taccgtccgt cattacttag gaaagtctta aaaaatctat aaagtaaaaa gagcccgaca
    10801 gctctttttg tttatactca atgaaaatca aaaagcaaac taggaaacta gccacgggct
    10861 gctcaaaaca ctgttttgag gttgtagata cgactcacat atatacggca agccgacgct
    10921 gacgtggttt gaagagattt tcaaagagta ttattctcca tcaaaggcat ctttaatatg
    10981 atcaaagaag ccttttttct ttggatttac tttcaagtca ccagcagccg cgaattcttt
    11041 caaggctact ttttggcggt cgttcaagcc tgtcggtgtt acgacattaa cagtaacgta
    11101 ttggtcacca actgcaccgc cacgaaggct cggtgccccc ttactacgta ggcggaattt
    11161 cttaccagtc tgagttccct ctggaataac caattcaaca tcaccgtgaa cagttggaat
    11221 atctactgta tcaccaagag ccgcttggac aaagttgagg ttgagattgt agaagatagt
    11281 cgttccttca cgttcaaact tgtcgctagc ttccacagaa actactacat acaagtcacc
    11341 ataaggtcca ccgttaaagc ctgcttcacc ttgaccagcg aggcgaattt gttgacctgt
    11401 ttccacacca gcagggattt tcacatgtac gctatgagct tgtttctcat gacctgttcc
    11461 atgacaggtt gtacatggat atttgatttc ttttccttgg ccgtgacaga catcacaggt
    11521 tacttggcga cgcatcatac caagaggagt ctgcgtatcg acgttaatga caccagcgcc
    11581 atgacagcgt ccacaagtga ctggacttgt ccctggctta gcaccagagc cattacatgt
    11641 acgacagcca gcttcacgat gatacttaac ttccttctca gttccgaaga tagcttcttc
    11701 aaaggtcaaa ttgacacgat actggagatc atctccttgg cgaggagcgt ttggattgcg
    11761 cgaagaaccg cctccgccga agaaacttga gaaaatatcc tcaaaaccac cgaagccacc
    11821 tgccccattg aaaccgccga aaccaccatc tccaccaaaa ccaccattgg cgcctgcagc
    11881 accatactgg tcataggcag cacgtttttg gtcgtcactc aaagtctcat aggcttcttg
    11941 aacttccttg tacttgtcct cagcaccagg ctccttgttg atatctgggt gatatttttt
    12001 ggaaagctta cgataagcct ttttgatttc gtctgccgaa gcgtttttgg atacccccag
    12061 acgatcataa aattcagtat tgttcataat tcaagataca aagggcgtca aacggacaca
    12121 gccatctagg agttttgacg acggacgctt atgtcctaga aaaaactatc tttttggcac
    12181 agtccgtagc ccgtgttcag ttacgaacac ccttattcct ttctattgat gttctgaatc
    12241 gaaccaccat ttaggtcgga ttcaattcct ttcttttata tttagtaaga aattctgaaa
    12301 cccgtgttca gttacgaaca ctctttgttc ctttctattg atgagacaaa acccaaacaa
    12361 atgagattcc gtcccttttt atcgaaaaac agaggctggg ttgcaacctc tgcaaataag
    12421 taaattaact ttattttgat tttaaatatc ctataagtac agaaatattt atatattttt
    12481 gtctcttctt agtatttgcc tatataattc caattgatca taagaaatac aactactgtc
    12541 caaatcatac caattatgaa cggtattaca aatttatatg tttgtatttc taatgatatc
    12601 atagctgata ccatcgccga tacaaatgca gacaacaata ctgaagtaac aaaattcctt
    12661 accgcttcat catttttgac acaactatca tgctcagcta atataatttc tctatatata
    12721 gtcaaacatt ctactggaat attatctata aaaccttttg ctgcttcata gttgtcagct
    12781 tgattacaaa aatcattata aacttttcgt gtatttttta gatactcatc atccaataca
    12841 ctcatcttat ttttccgtaa actctccgtc tacgacgtca tcgcctgcgt ttcctgttgc
    12901 ttgtgcgcct tctgctcctt cttgagcttg ttgcgctgct gcggcttgtt cgtagagttt
    12961 cacagcaagg ccttgagctt tttcgttcaa cgcttcaagt ttcgctttca tgtcgtccaa
    13021 gttgttgtct tcttgagctt tcttaaggtc atcaagggca gcttgggcag cgtcacgttc
    13081 tgcgtcgaag cctttacctt cagtttcctt gattgtcttt tcagtcgcaa agattgcttg
    13141 gtctacttca ttacgaaggt ctacttcttc tttacgtttc ttatcagctt cagcgtttgc
    13201 ttctgcatct ttcatcatgc ggtcgatttc ttcgtcagtc aaacctgagt tcgattggat
    13261 gacaatagtt tgttcttttt gagttccaag gtctttggcc ttaacagaca cgataccgtt
    13321 cttgtcgatg tcaaatgtta cttcgatttg aggaattcca cgaggtgcag ctgggatatc
    13381 agtcaattgg aagcgtccaa gagtcttgtt atctgctgcc attgggcgtt caccttgaag
    13441 aacgtggata tcaacggctg gttggttgtc tgctgctgtt gagaagactt gtgatttaga
    13501 tgttgggatt gtagtgttgc gatcgataag ttttgtaaat actccaccca ttgtttcgat
    13561 accaagtgac aatggcgtta catcaagaag gacaacgtcc ttgacatcac cagtaatcac
    13621 accaccttgg atagccgcac ccatagcaac tacttcatca gggtttactg atttgtttgg
    13681 ttctttacca gtttcagctt taacagcttc aacaacggca gggatacgag ttgaaccacc
    13741 aacaaggata acttcgtcga tttctgacaa gctcaaacct gcatctgaaa gggcttgacg
    13801 aactggaact tttgtacgtt caacaaggtc acgagtcaaa tcgtcaaatt tcgcacgagt
    13861 caaagtcatt tccaagtgaa gaggtccagc ctcacctgca gtgataaatg gcaagctgat
    13921 ttgtgttgaa gttacaccag aaaggtcttt cttcgctttt tcagccgcat ctttcaaacg
    13981 ttgcattgcc atcttgtcag tagacaagtc gataccgttt tctttcttga attctgctac
    14041 caagtggtca atgatttttt ggtcaaagtc gtcaccacca agtttgttgt cccctgcagt
    14101 tgacaatacg tcgaagacac cgtcacccaa ttcaaggata gagacgtcga atgtaccacc
    14161 accaaggtca aataccaaga ttttttcttc tttgtcagtc ttgtccaaac cataagcaag
    14221 agctgctgca gttggttcgt taacaatacg ttctacttca agaccagcaa ttttaccagc
    14281 gtcttttgtt gcttgacgtt gagcgtcgtt gaagtaagcc ggaactgtga taacagcttt
    14341 ggttactttc tcaccaaggt agtcttcagc gtagcctttc aagtattgaa ggatcatagc
    14401 tgagatttct tgtggagtgt attcttttcc atttgcagaa actttttcag aagttcccat
    14461 cttagatttg atagagataa ctgtatctgg gtttgtaact gcttgacgtt ttgcagcatc
    14521 accaacgatg atttctccgt ttttgaatga gactacagat ggagttgtgc ggtttccttc
    14581 tgggtttgcg atgattttgc tttcagttcc ttcaagaact gcaactgctg agtttgttgt
    14641 acctaagtca ataccgataa ttttagacat gtgtttttct ccttgttagt taattttcta
    14701 tttttctttt tgatactctt cttaagtggc gacgccgtca gagcttgact tcgtcaatct
    14761 ctttgactaa actttgagcc taaggtctca aaatttgcgc aaatagcacc acggcgaaga
    14821 gtatcgtctt tggttcgctt cgctcactat tacaaagcca aacatatttt atctttcttc
    14881 atagtttatt gtcgtttcgg acaagttttc tattatgtaa attgcgacac gaggagtcga
    14941 aatcgatttt atttcgacga cgagttagta aggaagctag gcaaacgtca tagcgattgc
    15001 cgttttctga cgagttgctt tagctaccgt cagaattgcc gaatcgaaca cgccctaagc
    15061 tctgagtaaa aaagatagat tttcttgtgt tcatcgaaca cttcgtcaat ctcctatttt
    15121 tactgcgagc tttttacgag ctttgtatct tagttataca ccactaccat tgctgggcgt
    15181 aggatgcggt catggagttt gtagcctttt tgaaagactt gggcgatggt atctactggg
    15241 tgttcatcgt ctgctgggag agtttggatg gccatatggt agttatggtc aaattcgcca
    15301 tctgctgcga tttcttcaat tccttcttct ttcaaagcgt gaatcaagct ttcttgcacc
    15361 atcgccaagc ccttcttcac atcatctgtc aaaccttcaa ctgcaagtgc acgctcaagg
    15421 ttgtcaagag atggtaagat tgcttttgcc aagtcctggc tacgataacg ttgcaagttt
    15481 tgacgttctt cattggcacg gcgttggata ttttgcattt ctgcatgagc gcgaagatat
    15541 ttgttttcga actcatctgc acgttcattt gccaagtcca actcagactt ttcaggagtt
    15601 gtttcttcag ctgtttccac aacttcctct tcttgaactt cttctacttc ttcatttttt
    15661 atatcttggg ccatgttcgc ctcctttaat gatttcaatc ttaatgtact tcgtaatgat
    15721 tactgctgag gtagcggtaa aaatctgtca acttcatggt caaaacacgg ttgaccacat
    15781 tgatttgatt gattagctgt tggtaatcca gattaactgg accgataatg gctagaattc
    15841 caactcctcg ataaggaatg aggaacttac tactaatcac tgctaggtca gctaaacagg
    15901 actcttgacc gtctgcaaca cgaacatttt gcatctgatc ctcacgcaac ccctcacgaa
    15961 tctccaaggc caccttttgc ggttggtcaa agaactgata ggctgctaga ttggcaaaat
    16021 tcaagagatg gaccttgccc gccatcacaa tgttttcgtt gaacatttcc ttaaagatgt
    16081 gttcaaagag atcgatgaca ttatccgttg ttgtaaagta acgctggata atctgcggaa
    16141 tctccgtccg aatcttgtag tgaatatcta aaacggtgtg accgaggaaa cgttcctgaa
    16201 tgatgctctt cagtttcagc aaatcctcct gcaagaagtt ccttggaatc agaaactgac
    16261 tagtaaccgt tcgcgactcg tctagggtaa ataccgccaa ggctgtatgt tgccccaaaa
    16321 caacgatatc aaaggctgtc aaacgttgcc tgctcggctc aacatccagt gccactaccg
    16381 tacagccact caggtctgtt agtaagttag cagcctcttg cagaatatcc tccaatttga
    16441 agaattcctg atcaaaggct ttgacaatct catatacctc attttcagcc agccggtcaa
    16501 aatccagtga gtgtttcaca tagtactgaa aaccagcaac acttggcatc cgaccgcttg
    16561 aagtatgagc cttctcaagc aacccttgtt tttctagttc cgccatgtca ttacgaatgg
    16621 ttgcactgct agagttaata gactcttgca aggcttttga tccgacaggt tcgtgcgttt
    16681 tggtaaagat gtcaataatc agatttaaaa tatcctgctg acgctctgta accatctcat
    16741 cactcctctc tgtctgatca attagcactc aatgcatcca agtgctaact catgattcta
    16801 ttatacaccc ttagaagaga atgtcaagac aaaaactcaa aaaattagca ctcttttatc
    16861 aagagtgcta aaaatcaatc tgaagaccta gaaccttgct attcatctac tcggtatttc
    16921 ctttttagtc tgaaataacc ataaattaga taagaaatca gaaaagcata taaaacaaaa
    16981 ataagaaaga aagacataga aagatcctct ctaaacaaac tcatacaaac aacaagacca
    17041 cctgagaaag tagctgtaca ggaacgaagt ctagattgca taacttccca tttgagccct
    17101 ttactcatac agacttgatc ctctggaagt aaatcagaag acgatttacg aagaatcgaa
    17161 caagaaccta ctcctatcaa ttcccaacct ctatctctaa aatcttgcag ttcatgctta
    17221 tactttttta agaaatctag aatcatagat acggtagatg acatcgtctg gttgacattg
    17281 gtcaaaatag aacaaaccaa aacgactcgt tctatacctc caacctttca aatgcatctc
    17341 atgtaaatgt tcttcttcct tgtccaaatc aacaatggtg aaaatccgaa attctactct
    17401 gctattcatt gtcttacccc aaaattagaa aacatgcctg gcgttattta ttagataatt
    17461 ctttccactt ttgactcaat ctccaaaaaa tataagaaat ctgaatcgca aaaactatca
    17521 ataaaaccca atctattatg aaaatcaaaa acactttcca actgaaagaa ctacctccag
    17581 tgacaaactt tgagaaaaac ggtagtagag ctaaaaagag aaataaaata ggaagcatcc
    17641 gcattgttaa aatccgtttg gcataaaaaa atctttattt aaacgaaaat attatggcaa
    17701 aatttacgcc agtttttgaa cggctgatgt agatatttta tactttcaaa atgtttaaat
    17761 gtgattattt atttttgaaa aatagatcac cagcccgact gaaagtgctt atagaatgat
    17821 aataagtcgc ctgccgaaaa cagcgaaaaa tagcggtgtt atgcggagat aatctgacgc
    17881 gatgcgaaag tatattgcat acttattttc aacaatttag cagagtattt ttataagtgt
    17941 gatataatag aagtataatt tgttctgata gtttatttta tggagaagta gatttttaga
    18001 atgcggaggg ttcaatatgg ttgagtttat aaagtctaag aaagaaatga gtgaggagga
    18061 tattaaagca aatttcatca ctcctgctat tgtatccaaa ggatggaaaa atggtgagca
    18121 tatcgcttac gaagaatact tcactgatgg tcgaattgaa gttagaggag ataaggctca
    18181 tcgtaaagaa ggaaaaaaat cagactattc actgtattac caatttggaa ctcgaattgc
    18241 aattgttgag gcaaaggata ataaacacag cgttcgagca ggattacaac aagctattga
    18301 atatggagag attttagatg ttccatttgt ttattcttcg aatggtgatg gctttattga
    18361 acacgaccgt atcacgagag aagaacgtga gctggagtta gacgaattcc ctactcgtga
    18421 agaattattt tctcgtatga cgaaggaaaa aggattgacg tacgaaatta cagaagctat
    18481 ctcaactcca tactatacag acgccttctc aatgaaaacg ccacgctatt atcagcaaat
    18541 agctatcaac cgtactattg aaacagttgc cagaggacaa aaacgagtaa tgtttgtgat
    18601 ggcaacagga acggggaaaa cgttcatggc ttttcaaatt attcatcgcc ttcgaaaagc
    18661 tggtttggct aaacgagttt tattcttagc ggatagaaac atcttagtag accaaacgat
    18721 ggctgaagac tttaggccat tcgaaaaggt aatgacgaaa attacaccaa aacttttgac
    18781 tgctcctgaa aaattaaatt cttttgaaat ttatctaggg ctttatcagc aactaactgg
    18841 tgaagatgga actgaaacac attatcaaaa atttgacaaa gacttctttg atttaatcgt
    18901 aattgatgaa gcgcaccgtg gttcagctaa ggaaaacagt aactggcgta agataattga
    18961 ttatttcagt tctgcgacac agattgggat gaccgctact cctaaagaaa ccaagaatgc
    19021 ttccaatacg gaatactttg gtgagccaat ctatacttat agtttaaaac agggaatcga
    19081 ggatggtttt ttggctccat atcgtgttat gagagttaat ttagatgtag atgtggatgg
    19141 ttatcgtcca gaaactggaa aagttgatgc taacggacaa ttaatagaag ataggtacta
    19201 cggcaggaaa gattttgata aaaccattgt cattgatgat agaacgcaaa gagttgccaa
    19261 gtttgtttct gattatatga agcaaaacaa tgcacgattt gataaaacaa ttgttttttg
    19321 tgttgatatt gaccatgccg agcgaatgcg tgctgcactt gtaaaagaga atctagactt
    19381 agtccaagaa gactatcgtt atgtcatgca agtaactggt gacaacgctg aaggaaaagc
    19441 tcaactggat aactttatgg atgtcaattc taattttccc gctattgtaa caacgtctaa
    19501 attattaacg acaggagtta atgctaaaac atgtcgtttg attgttttag actctaatat
    19561 ccaatccatg actgaattta aacaaattat tggtcgtggc acacgtcttt atcctcaaaa
    19621 ggggaaagaa ttttttacga ttattgattt tcgaaatgtt accaatttgt ttgctgaccc
    19681 tgattttgat ggtgatccag tgaaggtgct ggaaacaggt gcgaaaacag tcagtggttc
    19741 tacgcccggt ttcgtaagtg aggaaggtga cccagtagaa aaatatatcg ttacagacaa
    19801 gcaggttacc attcttaatt ctactgttca agtattggat gaaaacggga aactgattac
    19861 cgaaagcctg accgactaca ctcggaagaa tatcttaggt agctacgcca ctttgaacga
    19921 ttttatcaca gtttggcata cggcggataa aaagaagctt atcttagacg aactttataa
    19981 aaaaggagtt tatctagatg ctattcgaga gtcggaggga atatcagaac aagaaatcga
    20041 tgattttgat ttactcctaa aacttgccta tggtcaaaaa gaattaacca aaacggaacg
    20101 tatcaataag ctcaaacaaa gcggatattt atataaatat agtgaggaag cgcgtgctgt
    20161 tttggaaatt ttactgaaca aatacatgga taaaggtatt ggagaactcg aaagcattga
    20221 aacattaaaa cttccagaat ttcagatata tggtggaacc ttcaaaatca tcaatactta
    20281 ttttggagat aaaaaacgat atttacaagc aattaaagaa ttggagcaag agctatttac
    20341 agtagcttaa tgaaaggaaa gtatgtcaat tacatcattt gtaaaaagaa ttcaagatat
    20401 cactcgaaac gatgctggtg ttaatggtga tgctcaacgt attgagcaaa tgtcttggtt
    20461 attattctta aaaatttatg atagccgtga aatggtttgg gaattagaag aagacgagta
    20521 tgagtcaatt atcccagagg aattaaaatg gcgaaattgg gctcatgctc aaaatgggga
    20581 acgggtattg acaggcgatg aattacttga ttttgtcaat aacaagttat tcaaagagtt
    20641 gaaagagctt gaaataactt caaatatgcc tattcgaaaa acgattgtta aatcagcttt
    20701 tgaagatgcg aacaactata tgaaaaatgg cgtcttgtta cgccaagtca tcaatgctat
    20761 tgatgaagtt gatttcaata gccctgaaga tcgtcattcg tttaatgata tttacgaaaa
    20821 aattcttaaa gatattcaaa atgctgggaa ctcaggagaa ttttatacgc cacgtgcagc
    20881 gactgatttt attgccgaag ttcttgaccc aaaacttgga gaatcaatgg cagaccttgc
    20941 ttgcggaaca ggaggcttct tgacttcgac tctgaaccgt ttaagtagtc aacgtaaaac
    21001 tagtgaagat accaaaaaat ataatacagc tgtttttggt attgaaaaga aagcatttcc
    21061 tcatctttta gcagttacaa atctgtttct tcacgaaatt gatgacccta aaattgttca
    21121 tggaaatact ttggagaaaa atgttcgtga atatacgaat gatgaaaaat ttgacattat
    21181 tatgatgaat ccaccttttg gagggtcaga attagaaaca ataaaaaata actttccagc
    21241 agaattacgg agttctgaaa cagctgattt atttatggct gtcattatgt atcgtttgaa
    21301 agaaaatggt cgtgttggag ttattttacc tgatggtttt ctatttggtg aaggtgtaaa
    21361 aactcgcttg aaacaaaaac tggtagatga gttcaacttg catacgatta ttaggttgcc
    21421 tcatagtgtc tttgcaccgt atacaggaat ccatacgaac attcttttct ttgataaaac
    21481 aaagaaaaca gaagaaactt ggttttatcg tttagatatg ccagatggtt ataaaaattt
    21541 ctcgaaaact aagccgatga agtcagaaca cttcaatcct gttcgtgact ggtgggaaaa
    21601 tcgtgaagag attctggaag gtaagttcta caaatctaaa tcatttacac ctagtgaatt
    21661 ggctgagttg aattataatt tagaccagtg tggttttcca aaagaggaag aggaaatctt
    21721 aaatcccttt gagttgattc agaattatca agcggaaaga gcaactttaa atcataagat
    21781 tgataatgta ttagctgata ttcttccgct cgatcaggga ttcaaaaatc gacaagcaca
    21841 aacaaaacag tcgccatcat catttattga gataatatag tagattgaaa taagatgtaa
    21901 acaaatcgat taggaaagtt aaattagttt ctagaaattt ttagcagatg tagtgtacta
    21961 ttctagtctc aatttactat ggcttcaaat atatctttcg aaaaaatatt tacagatgtg
    22021 taattttgaa gcttgtaaaa gttagtaaac ttgtagattt cgatttgaag taacttgttt
    22081 tcttgcccga tattgttttt gaaattgaat ttttccatag tgactccttg attttcttct
    22141 acacgtctga tgataaatct aattcgcaaa agagtcaaga ggatttttcg aaaaataaat
    22201 agcgaccgaa atcgctattt taagggttat aggtatttga tggcttagac tgctgtgtga
    22261 ctgtttaccc acaggcaatc tttcttctat attagtatta gtaaaggtct aaataattat
    22321 caatttccca ttgtgaaacg aaggttgcat aacttgccca ttcgattcgt ttggcttcaa
    22381 ggaagctagt gtagatgtga tctccgagag cagctttaac cacttcatct tctgtcaaag
    22441 ctttcaaagc gttgtgaaga gttgatggaa ggtctgtaat accagcttcc ttgcgctctt
    22501 ctgctgtcat gatgtagata ttttcttcga taggagctgg tgcttcgatt ttattttcaa
    22561 taccatacaa accaacttcc aaaagaacag ccatagcaac gtaagggttc gccattggat
    22621 ccactgaacg caactcaaga cgagttccca taccacgtga agcaggtacg cgcacaagtg
    22681 gcgaacggtt acgaccagcc caagcaatgt aaacaggcgc ttcataacct ggaaccaaac
    22741 gtttgtatga gttaactgtt gggttcatga tggcagtata gttgtaagca tgcttgatca
    22801 aaccgcctag gaaatggtaa gctgtttctg acaactgcat tccttttgga tcatttggat
    22861 caaagaaggc gttatttcct tctgcatcaa acaaggacat attacagtgc atacctgagc
    22921 cagcaatacc aaattttggc ttcgccataa atgttgcgta aagtccgtgt ttgcgagcaa
    22981 tggttttaac aacaagttta aagatttgaa tcttatcaca agcacggaga acttcatcgt
    23041 acttaaagtc aatctcatgc tgtccaaccg caacctcgtg gtgactcgct tctacttcaa
    23101 atcccatttt ggtcaagaca ttcacaatct cacgacgtgt gttgtccgca aggtcagtag
    23161 gtgccaaatc aaagtagcca cccttgtcat tcacttcaag tgttgggtcc ccattttcat
    23221 ccaacttaaa taggaagaat tctggctctg gaccaaggtt gaaggatttg aatccaactt
    23281 cttccatgtg acgaagagct cgtttcaaat taccacgagg gtcacccgca aatggttcac
    23341 cttctgttgt atagacatca cagatcagac ctgcaacact tccattttca tctccccaag
    23401 ggaagactgt ccatgtatcc aagtccgggt acaagtacat atccgactca ttgatacgta
    23461 caaaaccttc aatagaagat ccatcaaaca taaccttgtt cgataagacc ttatctaact
    23521 gttcatctgt agcaggaatt tcgacgtttt tcatggttcc caaaatatct gagaacataa
    23581 gacgaataaa ggtaacattt ttttccttga cttcacgacg aatatctgca gctgtgattg
    23641 gcataagttt tctccttaat ctatgactac ttgcggttgc ctaaccgcga ccaaaaggtg
    23701 actgtactga agcaaaacgc ccctgttgga ggagttcatt gtgaagtgca cgacgtactt
    23761 cagtctgact aaccgctttc ttggatttcg cttcacgttc agcatatttt ttcttaatgg
    23821 cagcgatatt ataaccttca gagatataat ctttgatttc aagcagacga tccatgtcat
    23881 tcaaggaata catgcgacga tttccttcgt ttcgatcggg cttgatcaac tcttgatctt
    23941 cataataacg aatctgacgc gccgataaat cggtcaactt cataacactg ccgataggaa
    24001 aaacagccat atttcggcga aattcttttt ccttcattta caatttcctt ctttctgtct
    24061 attatagtct aaaaaaagac aaacgtcaat tgataatgtt ataaaatgta acattatttt
    24121 tcttttttct ctaaaaagag acgaatacga tcaatatcgt aatttacaat aattgcgaca
    24181 aaaactccca taaacgtttc tgatacacgc acaaacacgt acgaaattgt ctcaccactt
    24241 ggaattgata gggtaatgat taacatagct gctacaccac caataacccc tgctttgtta
    24301 ttcatggcta catttgtcat aatggttaac atggtgcaga ttggaacaac taccaaggtc
    24361 acccaaaagg cttcgtggaa aaaggtattt aataagaaga agaccaaggc atagagtcca
    24421 ccgatactat ttcctagaat acgcgaagtc ccaaaatgaa cactcttatc aaaactctcc
    24481 ctcaggctaa aaacggctgt caaagcacca atttgaagac ctttccagcc aaaaaagcca
    24541 aaaatcaaga gaactagaaa aacagcaata cctgttttaa aggttcgcat accaagtttg
    24601 aactgggatt tatcgaattt atatttttta aaataactca taatctcaac tttctatttc
    24661 cattttatca taaatcggtg atttttatga gtaatagttg agaggaagcg tttttatttt
    24721 aagcaaaaga aaagaggaac tttcatccct ctcttctttg atttgtttat aaaatcttat
    24781 ttttctgtca aggctgcaag tcctggaaga accttacctt caagaagttc cattgatgct
    24841 ccaccacccg tactaatcca tgagaacttg tctgcacggc caaggttaat cgctgcggca
    24901 gctgagtcac caccaccgat gattgattta actcctggtt gtttcacgat agcgtccatc
    24961 acaccgattg taccagcttg gaaatctggg ttttcaaata cacccatagg tccgttccat
    25021 acaactgttt tggcaccagt caaagcttcg tcaaatttgg cgatagattt tggaccgatg
    25081 tcaagaccaa ggaagccttc agaaactgct tcaccttcag tgtcacgcac ttcagtgtaa
    25141 ccagcaaatg cgttagcttc ttttgagtca actggcaaga tcaatttacc atttgctttt
    25201 tcaagaagag ctttcgcaac atccaatttg tcttcttcta caagtgagtt accgatttcg
    25261 ataccttgtg ctttgtagaa tgtgtaagtc atcccaccac cgataaggac tttatcagct
    25321 ttttcaagca agttttcgat aacaccgatc ttgtctgaaa cttttgaacc accaaggata
    25381 gccacgaatg gacgttctgg agtttcaact gcttcttgga tgtaggcaat ttcgttttca
    25441 agaaggaaac cagcaactgc tttttcaacg tttgctgaga taccaacgtt agatgcgtgt
    25501 gcacggtgag ctgtaccgaa tgcatcgttt acgaagatac catctccaag tgatgcccag
    25561 tatttaccaa gttcaggatc gtttttagat tctttcttgc cgtcaacatc ttcgtaacga
    25621 gtgttttcaa ccaagagaac ttgtccatct tcaagagcgt tgattgccgc ttccaattca
    25681 gcaccacgag tgacacctgg gaaaacaaca tcttgaccaa gttttgctgc caagtctgct
    25741 gctacaggag caagtgattt accagcttta tcagcttctt ctttcacacg tccaaggtga
    25801 gagaaaagaa ttgcacgtcc accttgttcg atgatgtact taatagttgg aagagctgct
    25861 gtgatacggt tatcgttagt gattacgcca tctttcaatg gtacgttgaa gtcaacacga
    25921 acgaggactt ttttaccttt caagtcaacg tctttaacag taagttttgc catgttacaa
    25981 aaactccttt atttatttta ttcgaaacta ttatatcaca ctttggaaat ataaggaaag
    26041 atttcacaag atttttcgat atttaatctt tatcttctct tttccgtctc aaggtcaagg
    26101 ctaaactagc aagaccgagg ctggctaagc ctgctattag ggcttcatta gcatcagctg
    26161 ttcctgtatt tggcaattgt ttgcttgctt cttctgattt aactgctgta ttttgagctg
    26221 gtttttcctg tgtagctact actgctggta ctgtttttac ttttgttcca atttcaacaa
    26281 tttctggaat cgcttcttgg atgacttctg ttgaacgaag acgacgctga ccgttttcat
    26341 caacttcaaa gacatgtctt aacagtccat ctcgtccctg tataatgact cgttgttccc
    26401 caactagcat ctcagcattt tcatgctctt gacgatgaaa ggcaaccttt tcctcttgaa
    26461 cttccaattt aggagccttt tgttgatcag aagccggttg ataagtaggt tttggaagga
    26521 ctttgttttg tggtgctggt ttagcaggtt gtggtttttc agcagattca taaacaaagg
    26581 cataatgagt aaagtgaggt gctgtaaaga taacatgact atccgtttgt tcaaaagcca
    26641 attctactgc ctctttgcct tcaggtaaga aaaatacttt cttaactttc ttatcttttt
    26701 caattgggat tttcacaata gaagcataag agagatcaac atcttgacct ttttcatcca
    26761 aaccttctat ttcaaagaca tgagcatctt ctccagcaaa gtatttcttc tcttcagcac
    26821 ttgcttgaac acgctctact ttcaaaccct tgatgacagt cttctcttta tttgagaagt
    26881 gtacttcaac acctgtttta ctatcagaaa agactgctga cttgtcttct ttcaataaag
    26941 caaccagatc ttttagactc tgtttcgctg ttgcaagctc ttctggactc aaatctactt
    27001 tttcaaccaa ggccttgttt ttctcaagaa gcggagctag ggcagaacct gaaggatggt
    27061 ttggtttggc agccaagagt tcttgagcct cacctgttaa gcgatcaagc tctgtctttt
    27121 cttccgtaaa tttctcttga ccattcagag ctttatgagc ttctgtcaat ttattaagtc
    27181 ggtcattgac ttgatcttgg gtgctagttt catggtcttt caacacttgt tcggccgctt
    27241 caattgcttt caagaaggct tcttttactt ctggtgaagc aaagttatag accaccttgt
    27301 tcttagcagc ttcaacttct gctaattttt gtttgaggta ctcatcgttc aatgctgctt
    27361 ttggagatac caaaacatca aagttgactt catgaccttg gtaacgaagc gtcaaggttt
    27421 gacgaccagt cttttgagca tcgtaaccag aaatttcaac tccctcatca gtaaaggaat
    27481 gttcttccat ggtgtcattg ctataagcca ctgcaaagcg tccttcagac aagtctaagt
    27541 tatcaccaac taggtaatct tttttcggtt cctgacttac ttcaattccc aaaatagttt
    27601 tcggacttgc ttcatcttgg ccagtgacag tcactgacaa attagcattt actggttgtc
    27661 ccaaatattg gagagtaaga ttctgttctc ccttatgatg cgtatcaaaa cctgatactg
    27721 atacacctgc gtgagttagg cgaatgagtt cgtcctcagt tcctccttca tactgaactc
    27781 gaagaacacc acctctaagg tccaaatcct ccccttcggc gtagcttgtt ttcttaggtc
    27841 ctgtttctag gctgactgac ttgattcttc tgtcatcttt tggaacggaa actgctagga
    27901 cattactaat ttccttgcct ggcaactggg tacgataata aagaagacca gattgatttg
    27961 tcaaatccaa tggtgcactt gctaggtctc ctccaacttc gctcttcaag gttgcgagcg
    28021 gagtttgaga atttggatta tcataaacgg taatagttgc tccagccggt acatctgcaa
    28081 agccaacttg taccttgtta ttgcctagag aacgggctgc agccttggcc atcggaatat
    28141 tgacactctc agtatcaagc ttttcataca ttttccagtt atagatacga atagccttcc
    28201 atggagttcc attgtcagaa gtgacaacat tcaagcgcca gtcttgagca gtgattggtt
    28261 tatcaagagt gatatctgtc acgtgtgctt tgttaccacg gacttcctta gctagcttcc
    28321 actcaccatc tgcatcttta taataaaggt caaagtcttt agtgttcatc aagccatcgt
    28381 taacagactc accaccagct cctgcatgat ccatgaccca tctaacaaca gtacgtggct
    28441 tggtcaaacg aatatccaca ctaccactca actgagctga agaccattta tctgacaagc
    28501 tagtaatggt accgttcaac ataccttcaa taccttctcc accttcagtc ttagggaaag
    28561 tactatcaat aactgttgca cctggaacga tattttcagc tagtggtttt ggtaggctgg
    28621 tatcttttac agtcataccc caatcaaagg ttgtggttgc agcttctgaa cgaactccat
    28681 ttttaccgac tgctacaacc ttcagttctt gagttgtacc ctgagcactt gctgagcggc
    28741 taacttttgg tagataaata gttgtagaag atgagccagt tagtaatttc cagctgtctc
    28801 catctttttc ataaacttca tagaaatctg catccttgtt gcctttaaat tgcacaactg
    28861 cttccgcttc ttgggcattt ttaagagatt gtttcactac agaaaagctt gtcggcgatt
    28921 gtggctcttg gtgattgtcc gagatagtta attgtccgag gttgaactga taatctttta
    28981 cagcaccttc atgctcaaaa aatagtttga ctgcatagat ggttttacct gctagtgagc
    29041 tgagagcaaa ttcttcattt gtccagttgt cagaaagggt tagctctttc catgcatctg
    29101 catcatcgaa tttgtagtct ggagttgtag agaatgccat ataaacttta gaaccttttc
    29161 ctcccttgtg ggcaacacga agtttggtct tctcagttac ttctaactta gtagaataaa
    29221 gtctcacatc ctgatctgtc ttaccggcta catcaccaga gaatttaagg gaatttccgc
    29281 cattataggc atctgtaaaa tcatattctg cacgaagttt ttcccctgtt gaagtctgcc
    29341 accagcgcca tgttggaaga acacctgata ctgaacgata attccactca gaatccttag
    29401 aaaccttacc atctacgaac cattttttac catgacctgt attaaaagaa gtagtaaaag
    29461 tattacctac cgctggcgta cggtccgcaa ctaggttagc aataccatac caatctttgt
    29521 cacctggttt ttggccagta gggtctcctt gataacctgt aaagaagata tcttcatttt
    29581 tatgataatc ttcaccagtt tttcctaaac ttgtaatggt atctggggca aataaaccaa
    29641 gagaaaggcg caatttccca ttttcgtcta aaatgtcatt ccacttaacc tttgtcttgt
    29701 aggaaccacc ctgttgcaat tccaaacctg caaatacatc ataaggatta cgaccaatcc
    29761 agttggcagt tgcaatagtg taatcatttt tagccttatc ccagttaaag ttagcaaaga
    29821 agttatctgc cggaacctta tctccttctg gttgcatgaa ttggtagttg tattctccca
    29881 aaccatcttg atgataacgt ccatagttat aggtcatggc atcgtaccaa gaatacttga
    29941 ttggatggtt taccttagca gcatattcct tgctatagag cataaactgg cgcatctttt
    30001 ctccaagagg tttaaccaaa tctccagttg tttcttggtt gatgaaatag ccatcatagc
    30061 cataatactt ggccatgtct accaatttac gggcaattgg gaagctacca tctgcgtctt
    30121 gcttcaaagc ttcagcaaat ctttcttgat ctgcaatact attagaccag ttgaagaaga
    30181 gtgtaccgta tacaggaacc ccgttacggt gacctgcatc aataacgtca ggagttggta
    30241 cgagaccttc ccagaagacc attgaatcta gatattgcca atagtcaaaa gcataggcct
    30301 tgaactcttc tccaccaaca gaagcatggt cttttgcttt agaattggtg tttgataagg
    30361 cttgaacttt tgcttccttg ctagcttttt cattgactaa atgacctgtc cgacgtgaag
    30421 cgaggacaac agatccgcgg ttaatagcat catcttcacg agcacctggt tcccatttta
    30481 acaattcttc ccaagaatta aatttgattt cctttggttt taatgttttt tctgtatttt
    30541 tagggacatc tggctggact tctttttcag tcttattagc ttctgctgct ggtttagact
    30601 catccccttg gttagttgct tcgggctttg cttctgtttc cttgtcagac ttaggttttg
    30661 cttctgcaga tggtgtttct gcaaccacct cacttgcttt ttcctctggt ttagctgcgc
    30721 tagctgcttc tgcagtttca gatgctatcg ctactccttc tgccttttct agcttgtttt
    30781 ctctagcatg ttccccttca ttctgcttat cagcttcatt ggtcgaatgc tcactctctc
    30841 ctgaaacaag ctctggatta gctccgctat tttcaggaac tgcagtttct tcagccaagg
    30901 ctggaccagc aaataaaaca gcaccaatca tcagcgagca ggctcctact gataacttac
    30961 gaatactgta acgacaacgt ctttcaaaaa atggattctt cattttctcc tcctaaaaga
    31021 ttgattttgt tgttttcaag aaagcgcttt atattctgta gttttttatc aaactctaga
    31081 accatgataa tcacattttt atcctaaaac atttttagac aaaaaacaat aactgtttgc
    31141 acaaatctaa aataaggtta aaaactctta aaaataatac acttatcaat tataattttc
    31201 ttttacaaac ttgacattaa cacttgttag atttactttt atcctttaaa atagaatagg
    31261 agatattccg cgattatttt tcggaggaaa aagaaatgtc cattaattgg caggaaattt
    31321 tatttcactt tttaggtggt ctggggctat tcttatatag catcaagacc atgggagacg
    31381 gtttgcaaca agctgctgga gatcgccttc gtttttacat tgacaaatat actagtaatc
    31441 ctttctttgg agttctggtt ggtattggga tgactgctct aattcagtct agttctggtg
    31501 taacagttat cacagtcggc ctggtcagtg ccggtctctt aaccttacgt caggctatcg
    31561 ggattgtcat gggtgctaat attgggacaa ctgtcacatc ctttctcatc ggttttaaat
    31621 taggtaacta tgccctacct atgctcttta tcggtgccgt ctgtctcttt tttacaaaaa
    31681 atcggacagt caataatatc ggacgcatcc tctttggttt cggtggtatc ttttttgccc
    31741 tcaatctcat gagcggcgca atggctccac tcaaggattt acaggtcttt aaggactata
    31801 tgattgagct aagtaagaat cctgttttgg gtgtctttgt cggtaccggc ttgaccttgc
    31861 taattcaagc ttcttcggct accattggga ttttacaaaa cctctacgcc ggcaatctaa
    31921 ttgacctaca gggagctttg ccagttctat ttggtgacaa tatcgggaca accattacag
    31981 ccatcattgc ctctttaggg gctaatattg cagctaaacg ggtagcagga gctcatgttg
    32041 ccttcaacgt tatcggaaca gtcgtctgcg ttatttttct agttcctttt actgtcctga
    32101 ttcattggtt tgaagctacg ctaaatctag caccggaaat gaccatcgcc tttgctcacg
    32161 gaacctttaa tattaccaac accattgtcc aatttccatt tatcggagct ctggcttact
    32221 ttgtaaccaa gattattcct ggagaggacg aggttgtcaa atacgaaccc ttatatcttg
    32281 atgaacattt catcaaacag gccccatcta tcgctctagg aaatgctaag aaagagctct
    32341 tgcacttagg aaactacgct gctaaagcct ttgacctttc ctataagtac atcattgatt
    32401 tggatgaaaa agttgctgaa aaagggcata aaaccgaaga agcaattaac accatcgatg
    32461 agcaattaac acgttatctc attgcccttt caagcgaagc tctcagccaa aaagaaagtg
    32521 aagtgcttac caatatcctt gattcctccc gtgatttgga acggattgga gaccacacgg
    32581 aggctctact caatctgact gactatcttc aacggaaaaa tgttgaattt tctgatgccg
    32641 ccttgaaaga attagaggaa gtttaccgcc aaactagtga ctttatcaaa gatgctctgg
    32701 atagtgtgga aaacaatgat attgaaaaag cacgcagtct tgtagaacgt catgaagcaa
    32761 tcaataagat agaacgtgtt ctcagaaaaa cccacatcaa acgcctcaac aaaggcgaat
    32821 gttcaacaca agctggggtc aactttatcg acatcatctc acactacact cgtgtatcag
    32881 accacgctat gaaccttgct gaaaaggttt ttgcagaaca aatctaagaa ccaagaagct
    32941 atccatcata attggatggc tttttacttt ttcctaagca agactaggct gaatgaaact
    33001 gaaagagtat tctgcagata tatagtatat tgaaactaga atagtacacc tctatttcta
    33061 aaacattgtt agaaatcgat ttgactgtc
//
LOCUS       DBJKQU010000021        31807 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.021, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000021 DBJKQU010000000
VERSION     DBJKQU010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31807
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.021"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(1..297)
                     /locus_tag="ACSUUC_001075"
     CDS             complement(1..297)
                     /locus_tag="ACSUUC_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054299.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="ACSUUC_001076"
     CDS             complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="ACSUUC_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HHQ8054300.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3571..4797)
                     /locus_tag="ACSUUC_001077"
     CDS             complement(3571..4797)
                     /locus_tag="ACSUUC_001077"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HHQ8054301.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4840..5532)
                     /locus_tag="ACSUUC_001078"
     CDS             complement(4840..5532)
                     /locus_tag="ACSUUC_001078"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HHQ8054302.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5705..7456)
                     /locus_tag="ACSUUC_001079"
     CDS             complement(5705..7456)
                     /locus_tag="ACSUUC_001079"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054303.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7446..9191)
                     /locus_tag="ACSUUC_001080"
     CDS             complement(7446..9191)
                     /locus_tag="ACSUUC_001080"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054304.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9400..9843)
                     /locus_tag="ACSUUC_001081"
                     /pseudo
     CDS             complement(9400..9843)
                     /locus_tag="ACSUUC_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521075.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
     gene            complement(9846..10302)
                     /locus_tag="ACSUUC_001082"
                     /pseudo
     CDS             complement(9846..10302)
                     /locus_tag="ACSUUC_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10436..11263
                     /locus_tag="ACSUUC_001083"
     CDS             10436..11263
                     /locus_tag="ACSUUC_001083"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HHQ8054305.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11275..11526
                     /locus_tag="ACSUUC_001084"
     CDS             11275..11526
                     /locus_tag="ACSUUC_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHQ8054306.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLSL
                     EECQLMLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLY"
     gene            11533..11661
                     /locus_tag="ACSUUC_001085"
     CDS             11533..11661
                     /locus_tag="ACSUUC_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HHQ8054307.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPNGYFLRFSE"
     regulatory      12044..12139
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12539..13120
                     /locus_tag="ACSUUC_001086"
     CDS             12539..13120
                     /locus_tag="ACSUUC_001086"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HHQ8054308.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13120..14382
                     /locus_tag="ACSUUC_001087"
     CDS             13120..14382
                     /locus_tag="ACSUUC_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HHQ8054309.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIAMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14469..15335)
                     /locus_tag="ACSUUC_001088"
     CDS             complement(14469..15335)
                     /locus_tag="ACSUUC_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HHQ8054310.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15322..16092)
                     /locus_tag="ACSUUC_001089"
     CDS             complement(15322..16092)
                     /locus_tag="ACSUUC_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-methyltransferase"
                     /protein_id="HHQ8054311.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16118..16972)
                     /locus_tag="ACSUUC_001090"
     CDS             complement(16118..16972)
                     /locus_tag="ACSUUC_001090"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0032775 - obsolete DNA methylation on
                     adenine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HHQ8054312.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELIPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17129..17533)
                     /locus_tag="ACSUUC_001091"
     CDS             complement(17129..17533)
                     /locus_tag="ACSUUC_001091"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HHQ8054313.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEDRQVRI"
     gene            complement(17603..19084)
                     /locus_tag="ACSUUC_001092"
     CDS             complement(17603..19084)
                     /locus_tag="ACSUUC_001092"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HHQ8054314.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(19103..20281)
                     /locus_tag="ACSUUC_001093"
     CDS             complement(19103..20281)
                     /locus_tag="ACSUUC_001093"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HHQ8054315.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20446..21453
                     /gene="galR"
                     /locus_tag="ACSUUC_001094"
     CDS             20446..21453
                     /gene="galR"
                     /locus_tag="ACSUUC_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HHQ8054316.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21499..22536)
                     /locus_tag="ACSUUC_001095"
     CDS             complement(21499..22536)
                     /locus_tag="ACSUUC_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HHQ8054317.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAVEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22537..22890)
                     /gene="nmlR"
                     /locus_tag="ACSUUC_001096"
     CDS             complement(22537..22890)
                     /gene="nmlR"
                     /locus_tag="ACSUUC_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HHQ8054318.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23134..24024)
                     /gene="czcD"
                     /locus_tag="ACSUUC_001097"
     CDS             complement(23134..24024)
                     /gene="czcD"
                     /locus_tag="ACSUUC_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HHQ8054319.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24157..24693
                     /gene="sczA"
                     /locus_tag="ACSUUC_001098"
     CDS             24157..24693
                     /gene="sczA"
                     /locus_tag="ACSUUC_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HHQ8054320.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24860..25666)
                     /gene="pnuC"
                     /locus_tag="ACSUUC_001099"
     CDS             complement(24860..25666)
                     /gene="pnuC"
                     /locus_tag="ACSUUC_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HHQ8054321.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26011..27531)
                     /locus_tag="ACSUUC_001100"
     CDS             complement(26011..27531)
                     /locus_tag="ACSUUC_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HHQ8054322.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(27524..28252)
                     /locus_tag="ACSUUC_001101"
     CDS             complement(27524..28252)
                     /locus_tag="ACSUUC_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHQ8054323.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(28267..29031)
                     /locus_tag="ACSUUC_001102"
     CDS             complement(28267..29031)
                     /locus_tag="ACSUUC_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HHQ8054324.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29035..29478)
                     /locus_tag="ACSUUC_001103"
     CDS             complement(29035..29478)
                     /locus_tag="ACSUUC_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHQ8054325.1"
                     /translation="MRDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30160..30456)
                     /locus_tag="ACSUUC_001104"
     CDS             complement(30160..30456)
                     /locus_tag="ACSUUC_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HHQ8054326.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLASFIKREESKYRGTATSALMYEELFKML"
     gene            complement(30478..31542)
                     /gene="pepA"
                     /locus_tag="ACSUUC_001105"
     CDS             complement(30478..31542)
                     /gene="pepA"
                     /locus_tag="ACSUUC_001105"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HHQ8054327.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
BASE COUNT         9460 a         7147 c         5647 g         9553 t
ORIGIN      
        1 ttatttcatt ttattatact ctgttaattc atatgagttt aaaccgattt catctttaac
       61 ctcgagtaaa gcagtttcaa atatttgttt aagagttttt gattctttac aattaaccga
      121 caaactttct gataaaatat gtacaacttc tgagactgaa taacctatct cctctttaga
      181 attatataaa tctgtagctc caccaataat ccaaaaatac tgattttgtg aacctacaat
      241 atcctcattt tctacggaac ttccttgtat cgaacaaatt ttatttatct ttaccataat
      301 acttcaaccc ttttagtgtc aaaagtaaac caattcctgt cactgttaag aatagttcca
      361 taatcttgtt cgaaccagtc tttggtaatt tttgttttac atctactatt tctttagatt
      421 tattaatatg attttcagtt tctctgccat ctccaactat tttatagttt acttcttctg
      481 tcttattatc ttgtttattg tcgatcttgt cattcatttg tctattatct ttacttgagt
      541 taaactctcc gttcttctgg ttactatcaa ttacattatt tgaattagat tgtttttcct
      601 ctttgttttt ttctttttcg tttttatcac ttaaattatt tgttacaatt ttgtaaagcc
      661 cattctccgt tacaatattg aaattaccat cgctatcacg tataacaggt tctttcccgt
      721 ttgcattaga tttgatgaat gatatatact taccggataa attataaaat tggttattta
      781 aaacggttat tttacccttt gaatcctcaa taacaattcc ttctttacca ccgaatatac
      841 tattctctga cactactaaa ttatcactaa ctcgtaataa ttcaatattt ggttgttctg
      901 tttccttaga attattatta attacatttt ttgttacagt aatatctgat acttttccta
      961 aatattctgc actatctttt gcaactcgta tcgcttttgt tttaggatcg gcaatattaa
     1021 atatattttc ggcgataacc acctgtttat ttaaatctaa taggtcttta gtgtttttat
     1081 agctataagc atttactaaa gctgctccgc tttctcgata atgtacactc tctcctttaa
     1141 ctttcttatc aaagcgattt cctttgatta atacatcagt gaatcctgta aaacgtacac
     1201 ctgcatacat catgttatca aaatgattat ttaaaatttt aatattagag gggttctgtg
     1261 tcgacaatgt ttgatagtgt gtgccaattg ctgttactaa ttccccagat ttatcacttt
     1321 tgccaaaata ggaattttga atagtcacat tttcagattt tttcccatca tcattcaagg
     1381 cataaggaaa accttttcta gttaatggtt caatctgaat gctctcctta cttatgattt
     1441 gcccatcctt catcgttttg ggtaaggctt gcccaagaaa acgagaatta tcaactaata
     1501 catttttcga acctgcaatt tgaatagcat gcccttgata actatccttg aatgttacat
     1561 tttttatagt tacgttattt gaattcccaa tagcaaatgc acctgaagaa tttataagtg
     1621 gtagattttt tgctttagtt ccttcttcat tcaaagcacc gttcatatca atcgtaccac
     1681 cagaataact aatatcttct gttgggcccc attctacttg cgcaccatca tccgtaaata
     1741 aacctgtcat aaaaacaatg gaagggtgat tcttaatatt tataccattt agaattgtag
     1801 ctttctcatt caattctaag tgtgtatgac tttttaaaaa aacaatttct tttactaaat
     1861 aagttccttc aggaaaatat acatttcctc cacctagccc ttgagctgca gcatctattg
     1921 catcttgaat tgcttgtcga tcatcatgaa tcccatcacc taccgcacca taatctttta
     1981 cacttaaagc agtatcttca aattcttttt tgataattct gtcacttata acatcttcct
     2041 tataactctt attttcatta gtagatgtta ctgtagattc aactgttctg ttgtctaatt
     2101 gtgaattgga acgaatagta ccattagagc tgatactatt aacacttaac gaattatcta
     2161 aaccattagt ggttgaatta gaggcaatca tttcagcaga acgattctga ttaacagttg
     2221 gtgaattatc taaatcatta gtaattgcat tagaagactc ttttgtagcc atcggtgaag
     2281 aactagtaac aacttcatcc gataaaatac cttggcttcc caaaattgaa attgccaata
     2341 gtaccgagca agtccccacc tttaatttac gaatactgaa tacctcatta ggaacaaaat
     2401 atttcatcag aacctccaat ttttttacta tttttaacaa ttgattatta cttttcttaa
     2461 aatagataga atgacaccgc tgtcattatc tttatcatat attttccaaa ttgaattgtc
     2521 aaggaataac acaagaaaat attaaaattt atactcttcg gaaatctctt caaactaggt
     2581 cagtgccgcc ttgccctaag tctaggttac tgacttggtc agttctatag tagactgaaa
     2641 ctataatagt acacctctac ttctaaaaca ttgttagaaa tcgatttaac tgtcccgatc
     2701 aatttgtcct attcttgttt cattttacta tatctacaac ctcaaagcag ggttttgagc
     2761 tatctatggc caacttccta gtttgctctt tagccttcca ttcaaaagtg atgctatctt
     2821 tcttagcttg aatataaaat atcccattta ctatatttaa atttgttgat atgttgtaaa
     2881 ttataaatga aagaacaaat accttgtcat acaagcattc gccagggata tttacctgaa
     2941 tatcgctcat atggcggatt gaaactaaaa cactacaata tatttcttaa atagaccttc
     3001 tataaaagct agatttaacc tcgataaaaa tagatgcagt gcttctaaaa tactggaata
     3061 gggcatatag gtaatcgtag acaagtgttt tatagattgt ctcgcaggag atctaatgat
     3121 gtatagcaag catcactaaa catatgggat atttgcgtta ttataatatc aacatgctat
     3181 aaattctatc atgcaaaaga atgactagaa catgaaagac aggcacaaaa ctttgaacaa
     3241 tattctgaaa acaaaaaaaa gacgctagtt tccacaatct cactcatgga aactcacgtc
     3301 tttcaaaaaa tagggtgaat tgaaaactag aacaagacac tagattttct aaatgatgtc
     3361 tagtaaggat tctaaatgct ataccaaatt gctcacatct tatttcaaac cacgggactc
     3421 ccacaagaaa ggaaaatcct ataaaaattc tctctctgag gagaaagagg cctcaactac
     3481 aggtgtaaac tattatcaat tgaaaacaac agtttttaca ctcaattaga ctttttaggg
     3541 acaggatcac tttcgcttga ctgtagtttg tcattttttt gataaagtta gcactttttc
     3601 agaaactgtt ttgaaagtct caatgatata gtctacttct tcatcgctta atttagtatg
     3661 aagagggagg gtaatttcat tctcaaagaa ggcataggcc ttaggatagt tcgtcatatc
     3721 aaatccaaga ttcttatagg ctgtcaagag aggaagcggt ttgtagtgaa cattacttgc
     3781 aattcctgct ttagccaatt cttggatgat gaggttgcgt tcttctaggc ttgctccttc
     3841 tacacgggtg atgtagaggt ggcgtgaaga ttcgacagtt tcagtcttgt gtgccaaagg
     3901 atggatgcga gaacctgcaa aaccactatc atagcggtcc acaatgtcct tacggcgttg
     3961 caacaaactt ggatagcggt ccaattgtac caaaccaagt gaagccatga tatcggtcat
     4021 gttgcactta taggctggtg taacgatatc gtattcccat gaccccagtt gcatcttggc
     4081 aagagcatcc ttagtttgcc cgtgaaggga aaggatttgg aattccttgt acatctcttc
     4141 gtcatcaatc actggattgg ctttccaagt cgcacttcca ccttctgccg ttgtaaagtt
     4201 cttaacagca tggaatgaga aggaagtaaa atcagcgata gaaccagaag gttgtccttt
     4261 ataagtagat cccaaagcgt gggcactatc agagacaatg acaatacggt taaaggcctt
     4321 ttgccacttg cttgaagcgg taaagaagtc acgttttttc tccacgactt ggaacaaacg
     4381 gtcataatcg caaacaatcc ctgcgagctc tactgggata atcaccttag ttttctcagt
     4441 gatagcttgc tcaagcaggt catagtccat ctcaaacgta tctgcttgga tatccaccat
     4501 gacaggggtt gctcccacgt gcgtaatgac actacatgaa gccgtatagg tcatggctgg
     4561 aacgatgact tcatcaccag gtcccacttc caaaacgcgt aaaatcaact ccagagcggc
     4621 tgtcgcagag ttgagacaaa cagtcttagg tgtctgtgtg taaagagaca agcggcgctc
     4681 cagttctttt gttttaggac ctgttgtgat ccaaccagaa cgcagggtat ccgctacttc
     4741 agcaatttct gcttctgtga tatcaggcgg tgaaaatgga atattgtaat ttggcattga
     4801 tttgctcctt ttatctgtac tcattttctt atgactactt tattttagta cctcaaacac
     4861 ggtttgaaac atgattttga tgtccccaaa gaaactaaac tctcggagat aggcgaggtt
     4921 atagcgcatc ttttcaggaa gaacatgctc cacataggcc tgatcaactg acagaccttt
     4981 ctccgtcatt tgactgatga tggtgtcctc atccttgtag ttgatgctgg ctggagaggt
     5041 aattcctgct tgcaagagca aggttgccat catttcaggg ctatactgct ctgtataacg
     5101 tggcacttca ggtcgtgtac cgacaaagga catctcacct ttaaggacat tgaccaactg
     5161 aggcagttcg tccaaacgga cacgtcggat gaaatttcca accttggtaa tacggctatc
     5221 gttagcagaa gtcaccagac ttcctttttt atccgcatcc gtcaccatgg tacggaactt
     5281 ccaaatcttg aaccgacggt tgtactgggt cacacgctct tgcttgtaaa tcactggccc
     5341 cttgctatcc aacttgatcc aaatgctcaa gatgagaaag atgggagaag ttagaaccag
     5401 taagaccaag gccaaaaccc agtccaagca acgcttgaaa atcagcgaac ccttcctttt
     5461 agagacaagc tggtagtaag actcaacctc gcttgatttc atttccacag gcaagtcttc
     5521 ccatttcagc atgctgttct cctttgtttt tattatacta tttgtcaaca tttttcatta
     5581 taccacaaaa tggaaaaggc ggtgaaagaa atctgtaatt tgaaggattt ccttctagta
     5641 ctcaatgaaa atcaaagtac agctttgaga ttgcagataa agctgacatg gtttaaagag
     5701 attttcaaag agtataggcc atggcccctg cctgcaaact atacatcttg tgataggttc
     5761 ctcccagagt caagagttcc tcatgggttc cactctcgat aatgcgtccc ttatccaaga
     5821 catagatgca gttggcgtct tgaatagtag aaaggcggtg agcgatagca atagttgttc
     5881 ggccctgtct catcttcgcc agagaagctt gaaccaaact ttctgtttca gagtcaatat
     5941 tggctgtcgc ttcatccaaa atcaggattt taggctggct ggcgactgtt ctagcaaagg
     6001 caagaagctg gcgctgccca gtagagaagc tcgaaccacg ctcggaaaca ggagagtcgt
     6061 acccctgagg aagttcttga ataaaggaat ctgcatccac aaaggctgcc gcagcctgaa
     6121 cctgctcatc actgatttct tggtacatgg cgatattgga cttaatagtt ccatgataga
     6181 ggaagggttc ctgtaaaacc aaaccgatgt tttttctcag ctcttcttga ctgaaatccc
     6241 tgatatccac atcatccaag agaactctcc ctgactggaa ttcataaaag cgcatgagga
     6301 cattgataat agacgatttc cctgaacctg tatgacctac aaaggcaatg gtttcaccct
     6361 tattaacaga gaaagaaatg tcatccagaa tcggatgttt accgtcatac gagaaacaca
     6421 catgttcaaa acggatattg ccttctttga ctttggcttg cccattttct tgaaggggct
     6481 cataggtcct ctcatcgatt aaggcaaaga cacggcctgc agaaaccata gacgtttgca
     6541 gtgttgaaaa gttttgcgtc acctcaatca aagggtcaaa gaggcggttg atgtactgga
     6601 taaaagcata catggtcccg gccgttatcc cgatagaaag accacgatag ccaaaatagg
     6661 tcatcaagac agcataacct agaagtttca acaaactcat ggcaggtctc aaaaagaggg
     6721 catccaaggc tacagaacgg ttggcatagg ccaagtgctc ttggttgatt tcatcaaatt
     6781 ctgcctgcag gcgcttctct tgattaaaag cctgaataat cctgattccc tcgatattct
     6841 ctgccagctt actattgata tctgacaaga gacttctggt tttctcgatg attttcactg
     6901 acttttttcg atagagattg accaaaagga aaatcaaggg gagaaagagc aagactaatg
     6961 ctgtcaaacg aaaatccagc accaacatgg tataaagggt tgtcagaaag ataaaaactg
     7021 ctgagataaa gctggataaa atcccagaaa acatatcact aatcgtctcg gtatcgttgg
     7081 tcaaacgaga aacgatagaa cctgctggcg tcttgtcaaa gtaagacatg cccagtttct
     7141 ccatattggc aaaggcatcc cgacgaatat ccctaacaat actgtaagac acgcgcgcaa
     7201 agagaagatt gccgacatac tgaactacag tttgtaggat gtagagacca tagtagacca
     7261 gcaaaacggt cacggctagt tggttaagat tgctgagata ctggtcgata aagtgggaag
     7321 ccacaagggg aatgacactt ttaatgaccg tcgtcgctag gagaaaactg agtgccaaaa
     7381 aggtaaggag tccataaggc ttgagatagg acatcaagcg cttcaataca gtccattgtt
     7441 cttgtttatt ctgcatcttc ttctcccttc atttccagct gctgagactg gtaggtttgg
     7501 gcataccagc catccaaagc tagcaagtct tcgtgcctgc ctcgttcgat aatttgacca
     7561 ttttgcagga ctaaaatcaa atctgcatgg acaactgcac tcaggcgatg ggcagtgata
     7621 atggttgtct tgtcctttcg cgtctccttg aggttgtcga taatcgcata ctctgtcttg
     7681 gcatctacgg cggataagga atcatccaaa atcaagatat cagggtctaa aatcatagcc
     7741 cgactcatag ccaaccgttg cttttgacca ccagaaagac tgactccttt ttcaccaatc
     7801 agcgtatcaa atccttgagg catgtctaca atatcttggt aaactcgggc tagcttagta
     7861 gcttcctcga ccgctgaaag gggcaagtta ggattgccaa agcggatatt gtctaggatt
     7921 gaagtcgcaa aaagaaactg gtcctgagga acatagccca tgagactgcg aaggtctgtc
     7981 agacgatagt cccgaatatc gtgaccgttt agataaatgg cgcccttatc cacatcgtat
     8041 tcacgcaaga ggagcttgat taaggacgtt ttcccagagc ctgtctgccc aaccaagccc
     8101 agtgtttgcc cttttgccaa actaaagtga atatccgtca gtgtttcctc attttcaaaa
     8161 gcaaagctgt caatggcata ctccaaacgc ccattttcaa taccatccag aggaaactcc
     8221 gggtcttgta caggagattc ctgagacaaa agattttcaa tccgctggta agaaaccttc
     8281 cctcgctgag tagtattaaa gaggaagccg atggccataa gaggccagac cagcatatcc
     8341 aaatagctga taaaggtgac tagattccca actgtaatct gcccttcctg aaccaccaag
     8401 gagccaacca aaagcgttaa aacataggac gaaccaacaa acaagagaac catagggtca
     8461 aagagactat catatttcat ggtttgcagg ttcttttgga aggttaattc attgactgcc
     8521 tgaaaagact tcaactcgtc tgcctgataa ccgaaagact tggtcacttt gatacctgat
     8581 acggactcct gtaccttgtt attgagttca gaaaaagcag cttgggattc gccaaaggcc
     8641 ttatgagtct ttctccctag gcgactagtc gcataggcca tgaaaggtag ggggagaatg
     8701 gcaacaagag tcatctgcca tgagatgcta aagagcatgg tcaacaaagt caccagagcc
     8761 gtgatagagg catccaccgc agacatgaca ccgccacctg ctaaacgagt caaggcattg
     8821 atatcattgg ttgcgtgtgc catcagatca cccgtccgat aggtttgata aaaggctgac
     8881 gacatttttg tgaaatgctt aaacaagcga gaccgcatga tctgtcccaa gcaataagag
     8941 gtcccaagga tatacatacg ccacacatag cgcaaatagt acataccaaa ggctgcaagt
     9001 agcaagtaaa ataggctaag aaggaggtcc tgctgggtta attgccccga tgtgatggca
     9061 tcaataaccc gccccataac cataggagga atgagattga ggacggaaac caagaccagg
     9121 gccacaattc cgactagata acggcgtttt tctaacttga aaaaccacca aagtttttga
     9181 ataatggaca taaaatccct ttctgattgc aaatggaaac ctgaggccaa tactcaatga
     9241 aaatcaaaga gcaaactagg aaactagccg caggctgctc aaagcactgc tttgaggttg
     9301 tagatagaac tgacgaagtc agtaacctac atacggcaag gcgacgttga cgcggtttga
     9361 agagattttc gaagagtaca agaccccagg tttttctttt tcataagtta cgactgtaac
     9421 agcacccttg tcatattcag caataaagat attggctaca ttgtcatgcc cttgtttact
     9481 gaggttatca agcaaccact cttcgctacg accaatcgat tccaagacat ctacttgaat
     9541 cacaccgtca gtcacaactg gatacttagg attttcatct cccatttgca caacgataag
     9601 ttgcccattt tgctcttgca cagctcgttt gacttgcttc atctggaaaa tcccttggct
     9661 acgaagtttg agggctacat ccgatgcaga caaaccaact gaacgacagg cttctgggtc
     9721 aatattccca tttttgataa ggagagttgg cttaccatca atcaaacgtt tcacaaagtg
     9781 aacattgttg ttgagccatt tgagagtcaa gaccagtttg attaaaattt cgatataatt
     9841 aagtgtcatt tgttcacatc caccagttca attgcgtctg tcttatacaa ttcgactttc
     9901 tctaacaggt acttgtctgg ctcacttccg tttagggcac gataatagcg atctcccacc
     9961 ttgataagtg cgccatctgt gtttgtggaa gtattaacat agacttctga cttgtctact
    10021 cccaaatctt tggaaacaac ctcgatgaaa tgaagtgaag tttgaaattt attgttagaa
    10081 acttgattgt tttgataagt cgtgatgctg accaaaagca gagctaaata aggccagagc
    10141 tgaaatcatg accaactcac gaaattcggt tcccttttta tcatggtatg ccttgaaagc
    10201 aaaaaaaact gtcacagcta atagaacaat cccaaagcca accatgatac cattttgctg
    10261 accgatttgg ctgagtacat agtcataaga gtagaatttc atatattttc actctctttc
    10321 ataaaatcat tcttaattat aaacgaaaga gagtaatttt tcaaaccata cgttggggaa
    10381 atagatcttt ttttggtata ataaaatcta taatctgaat gaaaaaggta actttatgaa
    10441 acttatctca tggaatattg attccctaaa cgctgcccta actagtgact cagctcgtgc
    10501 caaattgtcc caagaagtcc tacaaacctt ggtcgctgaa aatgctgata ttattgctat
    10561 ccaagaaacc aagctttctg ccaaaggacc tacaaagaaa cacgtggaaa ttttagaaga
    10621 actcttccca ggctacgaaa acacgtggcg ctcttcccaa gagcctgccc gtaaaggcta
    10681 tgctggaacc atgttccttt ataagaaaga acttacgcct acgatcagct tcccagaaat
    10741 cggtgcccct tctaccatgg acttggaagg ccgtatcatc actctagaat ttgatgcatt
    10801 tttcgtaacc caagtttaca ctccaaacgc tggtgacggt ctcaaacgct tggaagaacg
    10861 ccaagtctgg gatgttaaat atgctgagta tttggctgaa ctagacaaag aaaaaccagt
    10921 ccttgcgacc ggtgactaca acgtagccca caatgaaatc gaccttgcaa atcctgctag
    10981 caaccgccgt tcacctggat ttactgacga ggaacgtgct ggatttacca accttttggc
    11041 aactggattt acagacacct tccgccatgt tcatggcgat gttcctgaac gctacacttg
    11101 gtgggcacaa cgcagcaaaa cttctaaaat caacaataca ggctggagaa tcgactactg
    11161 gctcacaagt aaccgtatcg ctgacaaggt cactaaatct gatatgattg actcaggtgc
    11221 tcgccaagac catacaccga ttgtcttgga aattgacttg taaggatttt ctatatggac
    11281 tacaatgcgg tcattcccga gttgcttgta tcgaatatcg aacagtctcg gtccttctac
    11341 tgtggtttac tgggttttag gattgaatac caacgtccag aagaaaactt tctctttctt
    11401 tctcttgaag agtgtcaact aatgttagag gagggaacaa aggatcaact agctgaactg
    11461 acctacccct ttggtcgtgg agtcaatctc tcctttggca taaaggatgt ttcaaaactc
    11521 tattaaagag tgatgaaggc aaactatcct atttatcgtc ccttgaccaa aagaaagttt
    11581 cgtgtcagtg atccctatat ctatcctcat aaatttgcag ttttggatcc aaatggctat
    11641 tttttaagat ttagcgagta gaataataaa aattgggaaa agtctttaaa gttagaaaaa
    11701 ggcatattgt caggtgttta aaaacttgat agtatgcctt ttatgatgga aaaatcttct
    11761 aatactcttc gaaaatctct tcaagccaca tcaacgtcgc cttaccgtag gtatatgata
    11821 ctgactctgt caattctatc cacaacctca aaacagtgat ttgaggttgt ggatagcttc
    11881 ctagtttgct ctttgatttt catttagtat aaatgttagc ttacaatgca gtttttgttc
    11941 actccttctt ctgtttgttc gttttttaaa ccaaaatact aacaaaatag ttgatttata
    12001 aagttattta gtgtaaaata aaaacattgg ctcaaaccta tttaaaattg aatatcgttt
    12061 tacttgttta tgtcgtgaat tggcacgacg tttctacaag gtgccggaac acctaacaat
    12121 aagtaagtca gcagtgagat atggccgttt ttgccatgcc tatttggggg acttacttag
    12181 agattaagta ggtctttttt gaatattttt aatatttccc ttaattagtg cggacgggag
    12241 gtgaaattat cctgtgaata atttcaggaa tccagggaat ttcatcccta atttttgagc
    12301 ccctagctct ttcatttcta ggcttaggct aaaatagttc cccgaactat tttactctca
    12361 aaaatcccgt catagacaat aacaagatta ttgtctatga taccactaca acgggaaata
    12421 tttgataaga ctcgcttcgc tcgtaatagt tttatcaaat atatagtatt agcaaaaggg
    12481 atcactatag aaacatttaa acaacaagta aattaacttt tagactttag gaggtcttat
    12541 gaaattatta gaagagcgca tcctcaagga tgggcatatc ttgggtgata acatcctcaa
    12601 ggtagattcc tttttaaccc accaagttga ctttagcttg atgcgagaga ttggtaaggt
    12661 ttttgcggaa aaatttgctg ctgctggcat taccaaggtc gtaaccattg aagcgtcggg
    12721 tattgcccca gccgttttta cagctgaagc cttaaacgtt cccatgattt tcgccaaaaa
    12781 agctaagaac atcaccatga acgaaggcat cttaactgct caagtctact cctttaccaa
    12841 gcaggtgacc agcactgttt ctatcgctgg aaaattcctc tcaccagagg acaaggtttt
    12901 gattatcgac gatttccttg ctaatggcca agctgctaaa ggcttgattc aaatcatcga
    12961 acaggccggt gccacagtcc aagctatcgg tatcgtgatt gagaaatcct tccaagatgg
    13021 tcgtgatttg cttgaaaaag caggctaccc tgtcctatca cttgctcgct tggatcgttt
    13081 tgaaaatggt caggtcgtat ttaaggaggc agatctctaa tgcaaactca agaaaaacac
    13141 tcgcaagcag ccgttctggg cttgcagcac ttactagcca tgtactcagg atctatcctg
    13201 gttcccatca tgattgcgac agcccttggc tattcagctg agcagttgac ctacctgatt
    13261 tctacagata tcttcatgtg tggggtggca accttcctcc aactccaact caacaaatac
    13321 tttgggattg gactcccagt cgttcttgga gttgcattcc agtcggtcgc tcccttgatt
    13381 atgattgggc aaagccatgg tagtggcgct atgtttggtg cccttatcgc atctgggatt
    13441 tacgtggttc ttgtttcagg catcttctca aaagtagcca atctcttccc atctatcgta
    13501 acaggatctg ttattaccac gattggttta accttgatcc ctgtcgctat tggaaatatg
    13561 ggaaataacg ttccagagcc aactggtcaa agtctcttgc ttgcagctat tactgttctg
    13621 attatcctct tgatcaacat ctttaccaaa ggatttatca agtctatctc tattttgatt
    13681 ggtctggttg ttggaactgc cattgctgct actatgggct tggtggactt ctctcctgtt
    13741 gcggtagctc cacttgtcca tgtcccaact ccactctact ttgggatgcc aacctttgaa
    13801 atctcatcta ttgccatgat gtgtatcatc gcaacggtgt ctatggttga gtcaactggt
    13861 gtttatctag ccttgtctga tatcacaaaa gatccaatcg acagcacgcg ccttcgcaac
    13921 ggttaccgcg cagaaggttt ggcggtactt ctcggaggaa tctttaacac cttcccttac
    13981 accggatttt cacaaaacgt tggtttggtt aaattgtcag gcatcaaaaa acgcctgcca
    14041 atctactacg cagctggttt cctggttctc cttggactgc ttcctaagtt tggtgccctt
    14101 gcccaaatca ttccaagctc cgtcctcggc ggtgccatgc tggtgatgtt tggttttgta
    14161 tctattcaag ggatgcaaat cctcgcccga gttgactttg ctaacaatga acacaacttc
    14221 cttatcgcag ctgtttcaat cgctgcaggt gtcggtctca acaacagtaa tctctttgtc
    14281 agcatgccga cagccttcca aatgttcttc tcaaacggaa tcgtcgtagc cagcctactc
    14341 gccattgtcc tcaatgccgt attaaatcat aaaaagaaat aagaaaaaga ggtgcgagcc
    14401 tcttttttgt ttatcacaaa ttgattataa atacaatcaa tcccaattcc catctaattg
    14461 aattggacct atttcaaatt ctttaaaata ttatgttcca aatcgttaat attatataag
    14521 aatggtaaaa tatcaaatgt ttctcgtaaa ttattcttag ccttatacca accttgtcca
    14581 tcagtaatcc acataaactc aacattagga atagctttag tttcttcagc aatcattttg
    14641 taagatctag ccgtctcatt taattttgaa ccacttcctg aataaaaatt aacctcaatc
    14701 agataaagca cttgttcatt ttttatgaca aaatcaaaac gtttcacagt attcccatca
    14761 ttcgtaatag cagataaatc gacagaaaaa atttcctcta tttcattttg ttcaatctct
    14821 ttaaataaat tctctcctaa aatataccct tcagcttcaa gatagctttg aacaatattt
    14881 tccatcgcat ctccagtccg atttttgcgc ccattagtat ccataccaac ctcaacacct
    14941 gtaacgtagt caactaaatt tgatactaaa tgattttgca ataaatcaaa tatacctgat
    15001 ttttccaaaa acatagtata ttcttcaata ctatagtttc gtttactaaa atcaaaatag
    15061 aaatctttta tcggatcctt aacaataatc gtatctctca aacgtttagc aataagtaga
    15121 ggcacaactt tcaaaatttc tggataattt tgatataagt ctaaaaaatc ctcttgtata
    15181 tttttactac caataagact attcataata tttagagcaa cttttatact agatacattt
    15241 ttataaacct taggaaaatc tgtataataa gtccagtcag ctactgtgtc ggtcatcgtt
    15301 gacaaccact catcaaaatt tctagtttgt ttcattttct gcctccaacc tcttccttgc
    15361 aatttttaaa tattcttttt cagcatcgat acctataaat cttctaccta accgcttcgc
    15421 aacaacaccc gtagtgccac taccaacaaa tgggtctaga atatagtcac cctctttagt
    15481 agaggctaaa ataatacgtt ctaacaaata ctctggtttt tgagttggat gtttcccagc
    15541 ccatttttca actttctttg ttaaagaacc ggtccagaca tctttcattt gttttccatc
    15601 attcaattct ttcattaaat cataattgta gtaatgacga gcttttttat cattttttct
    15661 ggcccataaa atggtttcag tagaatgggt aaaataacga caagataaat tgggggcagg
    15721 gtttgttttc tgccaagtaa tattattcag aattttaaaa ccttcttgtt ctaatgccat
    15781 tccaactgag tatatgttgt gcaaactacc tgaaatccat accgtcccat taggcttcag
    15841 aacttctttt gctaggcgaa tccatttacg attaaactca tgtttttctt cgaatgaaga
    15901 aattttatcc caatctcctt tatcaacaga aactacttgt cccccagaat tagatattcc
    15961 accattactt aaaaaataag gtggatcagc aaaaatcata tccatacttt ctggtttcat
    16021 ttttgataag aacttgaacg tatctgaatg aacaagaatc atcttatttt tattgtagta
    16081 tggttttgtc ataagaacac ctccatactt atattcgtta tttttcataa tttgtgacta
    16141 taatttcaga aatttttcct cgacttgaag attttgctcc attagttcgg gtagcttcaa
    16201 cataatgtat attaaaatcc ttatacaact cctctactaa agcactagaa gaatttgata
    16261 acataacata agctcctgta tcactcaatc tcttaaaggc atctcttaat cttacttgat
    16321 ctgcaaaaga gaatccctca tgagtataag acgtaaatgc actcgtctca gacaatggaa
    16381 tatatggagg gtcaaaatac acaaaatctc ctgttcgaac atctacaatt gccttttcaa
    16441 aatctcccac tttaatttct agttgattgt tatttatata aactgaaata gcagatatca
    16501 attcctcatc aacaatttta ggattcttat aacgtccata tggaacatta aattgattct
    16561 tagaattcac acgatataga ccattaaagt tcactctcaa catatataga atacgtgcag
    16621 ctctttgtac ttcggacatc atatctattc tttcatcacg atctgcagaa cgtaaatcta
    16681 aataatattc ttttgaatta tattcctgat gaactttcaa aatttcaatc aattcttgag
    16741 gattgtcctt aatttgttga tagcaattta ttagttcagc gttaaaatca ttaataactg
    16801 catctttagg agccaaatca aaaaataaag ctccacctcc aacaaaaggt tcgaaatacc
    16861 tgttataggt tttaggtatt aattctctaa taacaggcaa taattgtctt ttaccacctg
    16921 tccatttcgt gaacggttgt aaagtaactt tctttatttc ttttatcttc atgcttttaa
    16981 ttataccata gaaattaaaa cacaactctt gtattttcta ccacattact aaattttcta
    17041 ttttagaatt aaatcatatc aatatcaaaa aatgagtaag gcaaatctta taaattccaa
    17101 aattcacctc actctattaa attactcttt atatccttac ctgtctgtct tctgaccgct
    17161 ggcctgtgac aaacatggta aaggttgctt tgcagacatt tctgccttct tgattggtga
    17221 tatccacatc cattacacag gttgtacgac cttgatggac acattctcct ttaatggtca
    17281 atacatcgtc gagttttcct gccttaaggt agttgataga ggattggagt gtcaccccat
    17341 caagtcccag cgagataacc accaaaccac tgatttggtc acatagcgtg aatagatagc
    17401 caccatgggc attgccatag tagttgagcg acgagttcac tactttggtc gtcaccacaa
    17461 cgtgaccatc tctcattttt tcaatttcgt aattttcaaa ggcagatata gcgtcaaaat
    17521 gaaagtcttt catcgtttcc tcctgatatt tcaaacgaca ctatgatact actttttata
    17581 ggactgtgca aggagaaagc tcctagtcta gtaaaattcc gacctgttcc acaaagcgca
    17641 taaaggctgt ctgaccttgt tctgtctgct tgtagactcc tgcatcctca agtacacgca
    17701 caaagatagc acccacagag tccttgacga ttgcaagggc tttttcttta tccgttaggt
    17761 ctggatgttg ggatttgagt tggtctgccc actcctgatg ataatcggca actgtaacag
    17821 cttctcctac aagatagcta gcgacttgct ccacttcttc tttcagacgt ggtggcaaga
    17881 ttgccaagcc catgacctca atcaagccga tattttcctt cttgatatgt tggacatcct
    17941 tgtggggatg atagatgcca tcaggatgct ctgctgaagt ctgattgtct cgcaagacca
    18001 agtccaactc aaactgtcca tcacgcttac gcgctattgg tgtgatggtg tgatgcggtg
    18061 tcccgtctgt ctctgctaaa atctgcacac tagaatctga atactgacgc cattcctgga
    18121 aaatcttatc agctaagtta atcaaatcct ctttggaatc cgaagtcaag cgtaggacag
    18181 acattggcca cttgataatt ccagccttga cctgctcaaa accagcaaat cggaaggtct
    18241 tttgcaaggg agccaattcc ataggaaata cgtgacggcc tccctgataa tgatcatgag
    18301 ttagaataga gccccccaca atcggcaggt cggcattaga tccagcaaaa tatcctggaa
    18361 actgctctac gatagccaac agacgttcaa aactctgacg actaatggcc atgggacgat
    18421 gctggccatc taaaaagata caatgctcat taaagtaagc atagggcgaa tactggaacc
    18481 cccattcctg accaaccatt tcaaaacgga taatccggtg gttgctgcga gctgggtggt
    18541 tgacccgacc atggtaaccc tcattctcta aacaaagttg acactgagga taattactag
    18601 cttgcaccaa cttggctacc gcaatctctt tcggatcctt ttcaggctta gagagattga
    18661 tggtaatttc aagttctcca taatcagatg gaacacgata agcgatattt ttagcaatgg
    18721 ccttgagttt gatgtagtca tttttccgac tgagttgata aaaatcctct atcgcttgct
    18781 caggagagta ggcataggct tcccagaagt cacgattgac ctgactcgga caaggagtca
    18841 ccaagtccat cagttcagta ccaaggattt cacgcgcagt ctgactatcc tcaatcatct
    18901 ctaatcgaac ggcttcctca actagctggt ccttgaggtc aatcaattta tccagattgg
    18961 tctcaacttc caaaacacct tctcccactc gtgccaaaac acgattggtc aggtagattc
    19021 gatccatttc ctcaaatgaa ctttcagaaa tgacatgtgt tacaaattta tctactaagg
    19081 tcactataga gcctcctttt gactagtcaa ggacgcgagt cccacctgca acttcagcga
    19141 tatagaagct tggagcgtat ccaactactt cctcgtagtg tttgcctaca gcttccttaa
    19201 aggcctcaac agtatctttt tgaaccaagg caatggcaca gccaccaaaa ccagcccctg
    19261 tcatacgagc accgagaact ccttcttgtg cccaagctgt gtgaacaaga gtatccaatt
    19321 ccaaaccagt tacttcataa tcatgctcca gagaaacgtg tgacgcattc atcaaacgac
    19381 caaatgtttc caaatcacct gcttgaaggg ctgcttgagc tttaagggta cgttggtttt
    19441 caagcacagc atggcgagca cgtttcaaac gattttcatc tttaatcaaa tagctatatt
    19501 ggtcaacggc ccactcgtcc aattcaccca gggtctgaat atccaaggca acttgcaatt
    19561 cttccactgc tttttcacac tcagcacgac gttcattgta tttagagtcc gccaattcac
    19621 ggcgtttgtt ggtgttcatg ataacaacga cattgtcctt caaatcaagt ggcaccaaat
    19681 catactctaa ggtgttggta tcaaggtaaa tagcacgttg atcagccccc ataccaatag
    19741 caaactggtc catgatacca gagttgactc cgataaagtt attttctgtt tgttttccga
    19801 ttttaaccaa atcgagacgc tctaatttta aatcaaagag atgctctgcc actacccctg
    19861 tcaagagctc caaggatgct gaagaagaca aaccagcacc atttgggata ttcccataaa
    19921 cataaaaatc aaaacctttg tcaatcacgt gcccagcttc ttgcaagaaa tgaaggacac
    19981 cttttggata attggtccag ttgtgctctt tttcaaactt gaggtcagcg agaggcactt
    20041 cgataatgcc cttgtcctca aagttagctg agtagaaacg caagacttgg tcatcacgct
    20101 tacgagctgc accgtaagtt cccaaggaaa tagcagcagg aaaaacgtgc ccaccgttgt
    20161 agtctgtgtg ttcaccaatc aaattaatac ggcctggtga aaagaaggtt tggtctgctt
    20221 cttgaccaaa aacagcaaga aagtctttgc gaaggacttc agtagtaaga tgttgtgcca
    20281 tatgaattct cctttgactg tccgttaagc catcttaacg tgtaatcgtt ttctttctat
    20341 tgtatccaag gaatttccca aggtcaatcc tttttactaa aattttacta aaatatcagt
    20401 aaaaagaaga aaaatatgat atactaacct aatcaaggag gatttatggc taccttaaaa
    20461 gacattgcac agctagcctc tgtctcaatc gcgaccgtat cccgtgtcct caaccgcgac
    20521 cagagcctat ctgttacaga agaaaccaga caccgtattt taaccgttgc tgaagagcta
    20581 ggctacacca aacatctcaa gacaggcgag tcccacaagc ccaagcaaaa gattgccatt
    20641 atccaatggg tcagcgaaca aggggagcta gacgacctct actactacca gattcgccta
    20701 ggaatagaaa aaagagccca agagttggac tacgatatct tgcgctattt taatgaccat
    20761 ccttttacct taagcgagga agtgattggg attctctgca tcggaaaatt tagccgagct
    20821 cagatttctg cctttgaaga ataccaaaag cctcttgtat ttctagacag cgatacactt
    20881 tccctgggac atacctgtat tatcacggat ttttacactg ctatgaaaca ggttgtcgat
    20941 tatttcctca gtcaagggat ggaccgcatc gggattctaa cagggcttga ggaaacaaca
    21001 gaccaagaag aaatcattca ggacaagcgt ctagaaaact tcaaaaacta cagtcaagcg
    21061 aggggaatct atcatgatga actggtcttt caaggaagat ttactgccca gtctggctat
    21121 gacttaatga aggaggccat tcagagcttg ggagaccaac ttccgccagc atttttcgca
    21181 gccagcgata gtttagctat cggtgccctc cgtgccctcc aagaagctgg aatcagcctg
    21241 ccagatcgcg tcagcctcat ttcattcaac gacaccagtc tgaccaaaca ggtctatcct
    21301 cccctctcta gtattacagt ttatactgaa gaaatggggc gagcaggtat ggatattctt
    21361 aacaaggaag tcctccacgg tcgcaaaatt cctagcctga ccatgctggg aaccagactg
    21421 acattaagag aaagtaccct aaatcaagaa taggataaca taaaaaacga atagagttct
    21481 aaaactccta ttcgtttttt attcgattac aatcatagac ttaattgtct tacgttcatc
    21541 catatctttg taggcttggt cgatatcttc cagtttataa cttgaagtaa agacgcgacc
    21601 tggattgata tcaccatcaa ggacggcttt tagtaaaaat tgcttatcgt atgttgtagc
    21661 agaagctgcc ccacctgcta cagagatatt ttgcataaat gtcgaaccaa gagcacgatt
    21721 attatagtgt gggactccta caaagcccat acgccctcca ttatgaagaa cacctagcgc
    21781 ctgttctata gcagcctccg taccaacaca ttcaagtgct gcgtctgctc ctccaccgag
    21841 gatttcacgc accttggtaa ttccttcttg accacgttct gcaacaacag ctgtcgcacc
    21901 tgactccata gccatctttt gacggtcttc atgacggctc ataaggataa tttgtgatgc
    21961 tccacgcatc ttagccgcga tgacagcaca ttgaccaaca gccccatcac cgataacaac
    22021 aaccttgtcc cctttttgaa catttgcaac acgcgccgca tgatagcctg tcggcatgac
    22081 atctgcaaga gtcaaaaggg actggagcat cccttctgta tagtcagaag gttgaccagg
    22141 gattttaacc agcgcccagt ttgcatagtg gaagcgaata tattctgcct gaaaatcacc
    22201 ccccaaatta ttgccaatat gattgtcgca agaaccgtca aatccagcaa gacaggcatc
    22261 acactcacca catccatgtg taaaagggac aatcacaaaa tcacctggtt tcaccgtcgt
    22321 aatggcttcc acagcttctt caacaatccc aatcgcttcg tgtccactat ttttgtgtcc
    22381 agctttcgtt tctggattac ggtacctcca taaatctgaa ccacaaacgc acgcacgaac
    22441 cacacgaata atcacatcat ccgcttctat tatttgcgga cgttcaatgc tagcaagtcc
    22501 aacctgacct gcctttgtat atactgctga tttcatttaa aattttcctt ccttataaag
    22561 tttaattttg agatttaaac gatttaaagc tgtctgtagc tgagacaagc gctcctctaa
    22621 tttttgcttt tcctcttcta aaataccaag cctctcctct ctcgtttcat ctcccttttg
    22681 gtagagcgac atatagtcaa ctaaactatc tacagagaca cccgccgaac gaaaacactt
    22741 aataaattcc agcgcttcga tatcctgatc ttgaaaatca cgaatcccag tagcagtacg
    22801 agtaatcggt ggcacaagac caacccgttc ataataccga atcgtatccg ctgaaattcc
    22861 caacaaatca ctggcagatt taatattcac acgctaacct cctctcattt cattcactga
    22921 attcacgcta ttctaactca cttatcttat tatataactt tgagttgact ccaagtcaag
    22981 cattttgtat ctaatcgaaa aatttttatc attaacaatc atatatctgg agtttataca
    23041 atgctcttct cttaccaatt tttgaaatat ttaaataata aagaaattac tctattccaa
    23101 ataagatagt acccaagtat ttttcacttt tttctaatgt tgatgctcat aactccgttc
    23161 caagtcacac acctttcgct tatgggtttg gtgagtttct aggtcagcat caatttcaat
    23221 ggtaatattt tgaaaaccac aatcttttag gaaaattcga atagactctt tacaagtttc
    23281 catatgttcc atttctttta gacaaacatg gacaatggca tttttttcca aagcatccat
    23341 agtccagaga ttaagctgat taaggctggc cacattgtcc aatcgctcca ggccactctt
    23401 tacttgcttg atatcaagac cttctggcac agcatccaag aaaatcttga gtgtagacca
    23461 aaaacgtgga agggcttttg aaagaataaa gaaagaaatg acaagggaca aaagaggatc
    23521 taggatatac cagtccgtaa atcgaagaac aatcgccatc aggataacag ctacccaccc
    23581 tagcgtatct tccagaaaat gcagactcag aatagactca ttctttgtct ttcccttacc
    23641 aaccaccaga ctcgctaaca gattgatagt aatcgcaata attcctaacc agagaatccc
    23701 ctcatcattg actggttgcg gatgcaaaat cttcgtgaca ttttccaaaa tgactagaac
    23761 agagcccgtt acgagaatca cagctgttac caaggctcct agcaggctaa accgcttata
    23821 gcccaaggtg tactgattgt cttcttcacg attggagatt gtttctagaa aagctgatat
    23881 tccaattgca atcgcatctc ccaagtcatg cacagagtca gcaagaacag cgctagaacc
    23941 aaatactcca cctgcaataa actcaacaat ggcataagtc aaatttaaga aaaaagccac
    24001 ccaaacagca tattttgcct tcatatttct cattcctttg ttataataga tttatgaaca
    24061 ccttgttcat tatcattatc cactaaaact caaagaaagg atagaagcaa aacgtcagct
    24121 ttattcagtt ctgaacaatt tgccttaagt gtccatatga ctaacattga ccgccgtatc
    24181 agcaaaacca aaaaagccat ctatcaagct tttatacaac ttttgaatgc taagggctac
    24241 gaggccacta ctgttcagga tatcattgat ctcgcagatg tgggacgatc caccttttac
    24301 tgtcactatg agagtaagga gcttcttctg gaccagctct gccgctacct cttccatcat
    24361 ctttttgaaa gagagcaagc catttcaacc gaggactacc tcgcccacct ctttctccat
    24421 tttcataaaa accaagacca tatcaccagt ctgctatttt ccaaaaatga ctacttcctc
    24481 cgtcaactcc ataaagagct agaacaccat gtctattccg tgctagctga taatttaaaa
    24541 gaagcccacc ctaatctgcc tacttcttac ctccaacact tggtcatgtc caactttatc
    24601 gagacattga cctggtggct caaaaaaggt caagatttca cagaccagga agttgtccaa
    24661 ttttatctag accttctcat tcctaaaaat tgaatataga gtaaagcttc agttgtctta
    24721 tttctaggtt actgagtttt ttatcttttc aacaacaaaa gaggacccgc cgatcctctt
    24781 tttcatacta taaatccttg attatcaact atatctgttt taatcgaaat ctcaaaacag
    24841 cactttcaaa catcttttcc tagttaagta aatcagtatt ctgcttagct gccttgctcc
    24901 attgatacca accaactaga ctgttaatga gataaattag atatttccct tgaatttgca
    24961 ggctttctcc ccaccagaga tagattgaaa agacattggt agccgcccag aatatccact
    25021 gttcacggta aacagctgtc atgaggattt gccctacccc attggttgca tctgtgattg
    25081 aatcacgata gggacgattg gcaccaatag actgataaat gaagccaaag gccaaccacc
    25141 aaagcacact aatggaaaga tactttgtcc agcccttgcc gtccagttta cgcgcgacaa
    25201 actcctgctt ttccttctta aactgtgcct gataaatcca aactagaagt ccaattggct
    25261 gcatgactgt gaagtaaagt gtcgtcagca cctcaccata aaagcctttc tgtagggcca
    25321 aaataaggta aataacagag ttaatcaagc caaaaagata attacttgct cgaccttccg
    25381 atacaaagat tacacagata atccctgtca agctacaaat catcccaatc cagtcaacaa
    25441 tacgatgttc gtaaaccaac tccagccaga gaggaaaact tcctaaaacc agcaaataaa
    25501 tccactgggc aaaactacga tgggcaaaga ggtcatccca gatagccttc atagttcctg
    25561 aaaatcctaa atcagccata gccgcaacca tacgacggta accacctgac atttcaccta
    25621 gggttgtttt gatattttca attttctttt gcaaataagt atgcatcatt tctccttttg
    25681 tttttaaaga gccgtgtctg gatagacttt cggacgcaac gctctattag ataatgaact
    25741 gcctatacac aagatttcta accttagtcg acatgagctg aaacctctta tttgttaagt
    25801 agttcacaaa atattataca cctattttat gaatagtcaa ctgtctttac agtaaaattt
    25861 tagaaaatca tgaaaatttt ctctttcttt ccattttaag tgacattcag tcattctcac
    25921 atcaaaaaag cccagacgaa attgtctgag cattctttta tctagtcgtt taaggaagtt
    25981 gagttcagta tgtttaaagt ctctgtccca tcatttcttc aacaaacctt gttcttggag
    26041 aaactccttg gctacttgct ttgctgactt gccttcaaca ccgacttggt agttgagctg
    26101 gctcatctgg ctttctgtaa tcttaccagc caatgtatta agaactcttt ccaactctgg
    26161 gtgtttcttg agaagagctt ctttcatgag tggagcccct tgataaggtg ggaagagttg
    26221 cttgtcatct tccaagacct gtaaatcata acgctccaat tccgcatcag tcgaataggc
    26281 atccgtgatt tgaatatccc ctgactgaat agcctgatag cgaagggctg gctccatggt
    26341 cgctacattg agattgagac catacattga ttgcaagccc ttatttccat cttcacggtc
    26401 gttaaactcg agtgtaaaac ctgccttcaa ctgcccttcc acttttttca agtctgaaat
    26461 ggtcttcaag ccatattctt gagcaatctt tttcggaaca gctacagcat aggtgttttg
    26521 ataagacatg ggtttgagat aggctagatg atcctgctta gcaatgccat cacgcgccac
    26581 ctgataaacc tgttctggtt catgactcac cttgggtgat ggttgaagca aactttcagt
    26641 caccgtacca gtaaattcag gatagatgtc aatatcgcct tttttcagag cttcataaag
    26701 gaagcttgtc ttcccaaaat tcggtttaac agtcgcagtc atgctggtat tttcttcaat
    26761 cagcaactta tacatattgg ccaaaatttc tggttctgga cctattttcc cagcaataac
    26821 caagttttcc ttctcttttt gaaccaaaag agctggacta taagacagac ccagtaataa
    26881 agccaccaag gcaaaacctg agaaaatcgt ccgtaatttt gctttttcca tcacttttag
    26941 taggaagtta aaggcaatgg ctagcactgc agaagaaagt gccccaatca aaatcaaact
    27001 ggcattatta cggtcaattc ccaaaagaat aaaggaacct agtccccctg caccaatcaa
    27061 ggccgccaag gttgccgtac cgataatcaa aacagctgcc gtccgaatcc cagacatgat
    27121 aacaggcatg gcgagtggaa tttcaaattt cttgagacgt tcccatctgg tcatcccaaa
    27181 ggcaatccca gcctcttgca ggttcggatc aattcccttc agcccagtga tagtattttg
    27241 caaaataggg aaaatcgcat aaatcactag agctgtcaaa gccggcaagg tcccaattcc
    27301 catcaaaggg ataaagagcc ccaacaaggc cagagacggg atggtctgga aaatacctgc
    27361 aatctgcaag acccagtcgg ccagcttctc atgatagcga agaaaaacag ccaagggaat
    27421 cgcaagcaaa atagctagta acaaggtcaa aagcgacaac tgcaaatgtt gagatagagc
    27481 tgtcaaccaa tcactaaaac gatcctgaaa agttgcaatt aaattagtca tgaacactac
    27541 ctccaaacaa gtctgctaca aagtctgttg caggcgcttt taaaattgtc tcgggattcg
    27601 ctacctggcg aatttctcca tcctgcaaga cagcaatacg gtccgccaac ttcaaggctt
    27661 catccgtatc atgggttaca aaaatcgttg tcatcccaaa ctctttatgc aattcttttg
    27721 tcagaacctg caactgtttt ctcgaaatag catccaaggc cgaaaagggt tcatccatga
    27781 ggaaaatctt gggctgacca atcatagctc ggacaatacc gacccgttgc tgttctccac
    27841 cagataattc actaggtaag cgatgcccat actcggctac tggtaaacca accttagcca
    27901 aaagctcttc tgttttcttc gtaatttctt ccttgctcca ccccttcatt tcaggaatga
    27961 gagcaatatt ttccgcaact gttagatttg gaaaaagagc aatagcctgt aaaacataac
    28021 cagtagaaag acgaagttca cgctcatcat agtctttgat gcgcttccca tccatataaa
    28081 tatttccatc agttggttcc aaaagacggt taatcatctt gagcatggtc gtcttacctg
    28141 acccagaagg ccctactaaa accataaatt ccccatcctc aatctgtaag ttgacatctc
    28201 tcaagacatc cttttctgtg tagcgcagtg ctacattttt gtattcaatc attctttgtc
    28261 ctcaatttaa aacttccctc gattggtcaa gtcttctacc ttaggcataa cttccttatt
    28321 atcccaatgc tccacaattt tcccgttctc taaacggaag atatcgtact gggcataagc
    28381 aacgccatca atctgagtct gaccatagct aaccacatag tttccttgtc ctaagagttg
    28441 gaaaacaaag tcaaaagtga cactatattc agccacatag tttttataag cagcacttcc
    28501 ttgtccaata tcatgattat gctgaatcaa atcgtctgcc acataatcac tccactgctc
    28561 tagctcccca ttttggaaaa tttctgtcaa gaaacggcga accagctttt tattttctgc
    28621 tttcttgtcc aaatccttga tttcaaaatc tccaaaaatt tgatctagtt ggtcattttc
    28681 aggtgttcga tagtagtcaa cgacatccca atgctcaaca atacgaccat tctcatccgc
    28741 acggaaagta tccgtcgtca cccattgagc ttctccacca ttcagatatt gatgaacatg
    28801 aacaaagacc agattgccat cctcaatggt gcggacaatc ttaatctgac gctctggatg
    28861 acgctcaaag aaatctgcaa agaaggctgc aaatccttct ttcccgtcag gaacacctgt
    28921 cgaatgttgg atataggtat cccctacaga ctgggcttga gcctcagcaa ctcgtccgtc
    28981 ttgaatggca tggatgtata ggttgtgagc atttttcact tgttgtgaca tattctaaac
    29041 ctcatttccc ttctctttca gattcgccaa aattctttct tgaaaacctt caaattggtg
    29101 aatttcttcc tctgaaaatc ctttgtaaaa gatagtatcc aatttctgac tgacacgatg
    29161 ccccacttct ttctgggact tgcctaactc cgttaaaact aaatacttct tacgcttgtc
    29221 ttttccacac ggactaacaa ttacaagctt ttgttcctct agctttttta tcatagtcgt
    29281 cagcgtatta ttcgcaagcc cagtcgcaag cgcgatatct gtcgcagttg cgcagccagt
    29341 ttcactattc cataaaaccg ctaaaatctt gccctgttca cccctataaa gagcctcagg
    29401 atcttgactc agtaactttt gaaaaatccg cccattcaac aaacgaatat gatgggctag
    29461 caaatgacta tctctcataa cacctccaat ttatttcgat atcgaaatga ataaaacaat
    29521 tgtaacactc atcgttctat ctgtcaacta tttcgatttg gaaataattt ttgataatta
    29581 tccacaccac catactccgg ctcaactaac ttttaacgag agtttctaaa ttccttcgtc
    29641 ctccagtcta caaaagcctt ccatccgtac tatcctatat tttatgaggg gacacatttt
    29701 tcctatcaga gcatttattt taaagataga agtaaatcat aattgcttcc atctgttctt
    29761 ttatagtata ttgaagttga actagggcac tgtatcttct aaaacattga taaaaagcga
    29821 tttgaatttc ccaatcaatt tgttcgtatt tatagcattt tgcaactgga ataggacacc
    29881 atgactgcta aaagatttct ataaattcat ttaatttcct caatcaattt gttcatatct
    29941 tatttcatcc cgttataatt tcaccttacc ctatcttttt cgtagcaccc ttcaaacagc
    30001 ctatccccta ccgtttgacg attcctcact tcgctccact tccattacag aagtttcttc
    30061 actactatgg tctcggctga cttctcatga ttccttgtta ctactatttg aacgctcacg
    30121 agataggtct tataaaaaat gctttgatcc acaatggaat caaagcattt taaagagttc
    30181 ctcatacata agcgcagaag tcgcagttcc tctgtacttg gattcttctc ttttgataaa
    30241 gctagccaag ttgagcaact caggtgctgg atgtttggga tttaggagca attcacgatt
    30301 gaccaggcct gagagacgaa ctgcctgcaa ttgctcattt gtagtaggca gttttttagt
    30361 agtctctagg agagcagcaa ctaaatcttc actcaaatca tgtcgagcat gattgtaaag
    30421 atcttttata aggctttcta ggtttggttc taccatccct accacctccc ttatggttta
    30481 ataatgttta atcaaatcaa ccgttgaacg atccaatttc ttcaccaagg cttgtaagaa
    30541 agcttgcgct tctaggaagt catccattgc atagagggtt tggtgagaat ggatataacg
    30601 agcgcagaca ccgatagttg ttgatgggac accaccattt ttcagatgag ctgcacctgc
    30661 atctgttccg cctttaccac agtagtattg gtacttgata ccagcttctt cagccgttgt
    30721 caaaaggaaa tccttcatcc ctggaagaag caagtgacct ggatcataga aacgaatcaa
    30781 ggttccatct ccaatcttgc cttgaccacc gtagacatca cctgctggtg agcaatcaac
    30841 tgcgaggaag acttctgggt caaacttggt tgtagaggta tgagcgccac gcagaccaac
    30901 ttcttcttgg acgttagaac ccagatagag ttcattgccg agtttttgac ctgataaagc
    30961 ttcagctagc tcgcttacca tgaggacacc gtagcggtta tcccaagctt ttgagatgat
    31021 atttttttca ttggctgtca aaattgcaga actatctggt acaatggtat caccaggacg
    31081 gatgccaaaa ctttctgcct cagccttgtc cgcaaaacca ccatcaaaaa cgatatcggc
    31141 aatggctggc atggttggtc ccccctttcc acgagtcaaa tgcggaggaa cagaacctga
    31201 aatcacagga atttcatgac catcacgagt caagagtttg aaacgttggc tgctaactac
    31261 catggggttc cagccaccga tttctacgac acggaaggta ccatctggct tgatttcgct
    31321 gaccataaaa ccaacttcgt ccatatgaga agcgaccaag acgcgcggtg catccacagc
    31381 ttctgaatgt ttgataccaa aaataccacc caagccatct gtcaccactt catccacatg
    31441 cggtgtcaac ttttcacgaa gataagcacg gacaggcgct tcatgacctg agactgcagc
    31501 aagttctgtt acttctttaa tttttgaaaa taatgttgtc atttcagttc cttctttctt
    31561 tcatccattt taccactttt tataggagaa ggatagtggg aaggtggatt tctaagttag
    31621 tatcttagtc ctgctctatc ttaaaaaagg atagtattct cttgcatgta gtgcaaaatc
    31681 tagtaaacat tccaaaatta actcgaatat ttatttccaa acaaaaaaca atacaccatc
    31741 aaagttgttt agatttttca tgaaatttac agaaaatagt tgacttccct ttcttctttc
    31801 tttaaat
//
LOCUS       DBJKQU010000022        29898 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.022, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000022 DBJKQU010000000
VERSION     DBJKQU010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 29898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29898
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.022"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(31..786)
                     /locus_tag="ACSUUC_001106"
                     /pseudo
     CDS             complement(31..786)
                     /locus_tag="ACSUUC_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(924..2546)
                     /gene="groL"
                     /locus_tag="ACSUUC_001107"
     CDS             complement(924..2546)
                     /gene="groL"
                     /locus_tag="ACSUUC_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HHQ8054328.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2562..2846)
                     /gene="groES"
                     /locus_tag="ACSUUC_001108"
     CDS             complement(2562..2846)
                     /gene="groES"
                     /locus_tag="ACSUUC_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HHQ8054329.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKAAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(3116..3511)
                     /locus_tag="ACSUUC_001109"
     CDS             complement(3116..3511)
                     /locus_tag="ACSUUC_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HHQ8054330.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3589..4350)
                     /locus_tag="ACSUUC_001110"
     CDS             complement(3589..4350)
                     /locus_tag="ACSUUC_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HHQ8054331.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHVINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(4383..5009)
                     /gene="ytpR"
                     /locus_tag="ACSUUC_001111"
     CDS             complement(4383..5009)
                     /gene="ytpR"
                     /locus_tag="ACSUUC_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HHQ8054332.1"
                     /translation="MIFTYNKEYVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(5025..5342)
                     /locus_tag="ACSUUC_001112"
     CDS             complement(5025..5342)
                     /locus_tag="ACSUUC_001112"
                     /EC_number="1.8.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HHQ8054333.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(5339..5638)
                     /locus_tag="ACSUUC_001113"
     CDS             complement(5339..5638)
                     /locus_tag="ACSUUC_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HHQ8054334.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDLFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFIYENEDLVYEEEVL"
     gene            complement(5836..5916)
                     /locus_tag="ACSUUC_001114"
     CDS             complement(5836..5916)
                     /locus_tag="ACSUUC_001114"
                     /inference="COORDINATES: protein motif:HMM:NF039231.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054335.1"
                     /translation="MASSGKMLRNTYTPDSYYVGNLGAWQ"
     gene            complement(5923..6114)
                     /locus_tag="ACSUUC_001115"
     CDS             complement(5923..6114)
                     /locus_tag="ACSUUC_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HHQ8054336.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(6275..6949)
                     /locus_tag="ACSUUC_001116"
     CDS             complement(6275..6949)
                     /locus_tag="ACSUUC_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LiaF transmembrane domain-containing protein"
                     /protein_id="HHQ8054337.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(6955..7401)
                     /locus_tag="ACSUUC_001117"
     CDS             complement(6955..7401)
                     /locus_tag="ACSUUC_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HHQ8054338.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7503..8018)
                     /locus_tag="ACSUUC_001118"
     CDS             complement(7503..8018)
                     /locus_tag="ACSUUC_001118"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HHQ8054339.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVCVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLFLHVS"
     gene            complement(8015..8377)
                     /locus_tag="ACSUUC_001119"
     CDS             complement(8015..8377)
                     /locus_tag="ACSUUC_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HHQ8054340.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8443..9474)
                     /locus_tag="ACSUUC_001120"
     CDS             complement(8443..9474)
                     /locus_tag="ACSUUC_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHQ8054341.1"
                     /translation="MDFLLMGALFIVLPQTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATVHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            complement(9481..10302)
                     /locus_tag="ACSUUC_001121"
     CDS             complement(9481..10302)
                     /locus_tag="ACSUUC_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8054342.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPA
                     SMMMGMPFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLM
                     RTTNDITQVQMLITMDLQVVTCGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            complement(10319..10789)
                     /locus_tag="ACSUUC_001122"
     CDS             complement(10319..10789)
                     /locus_tag="ACSUUC_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHQ8054343.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(10913..11629)
                     /locus_tag="ACSUUC_001123"
     CDS             complement(10913..11629)
                     /locus_tag="ACSUUC_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHQ8054344.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12510..13919)
                     /gene="ply"
                     /locus_tag="ACSUUC_001124"
     CDS             complement(12510..13919)
                     /gene="ply"
                     /locus_tag="ACSUUC_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HHQ8054345.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQHEKITAHSMEQ
                     LKVKFGSDFEKIGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLRQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            complement(13930..14340)
                     /locus_tag="ACSUUC_001125"
     CDS             complement(13930..14340)
                     /locus_tag="ACSUUC_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054346.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDYLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(14333..14941)
                     /locus_tag="ACSUUC_001126"
     CDS             complement(14333..14941)
                     /locus_tag="ACSUUC_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054347.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14954..15412)
                     /locus_tag="ACSUUC_001127"
     CDS             complement(14954..15412)
                     /locus_tag="ACSUUC_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HHQ8054348.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15537..15668
                     /locus_tag="ACSUUC_001128"
     CDS             15537..15668
                     /locus_tag="ACSUUC_001128"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054349.1"
                     /translation="MNYEASKQLTDTRFKRLVGVQRTTFEEMLAVLKTAYQKSRTSW"
     gene            15646..15933
                     /locus_tag="ACSUUC_001129"
                     /pseudo
     CDS             15646..15933
                     /locus_tag="ACSUUC_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(16674..16934)
                     /locus_tag="ACSUUC_001130"
     CDS             complement(16674..16934)
                     /locus_tag="ACSUUC_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054350.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(16993..17544)
                     /locus_tag="ACSUUC_001131"
     CDS             complement(16993..17544)
                     /locus_tag="ACSUUC_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054351.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(17534..18319)
                     /locus_tag="ACSUUC_001132"
     CDS             complement(17534..18319)
                     /locus_tag="ACSUUC_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054352.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLKGKMLEIWKYRPFVSEFWNDFKNNH
                     DKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(18727..19152)
                     /locus_tag="ACSUUC_001133"
     CDS             complement(18727..19152)
                     /locus_tag="ACSUUC_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054353.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(19283..19672)
                     /locus_tag="ACSUUC_001134"
                     /pseudo
     CDS             complement(19283..19672)
                     /locus_tag="ACSUUC_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            complement(19685..19891)
                     /locus_tag="ACSUUC_001135"
     CDS             complement(19685..19891)
                     /locus_tag="ACSUUC_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054354.1"
                     /translation="MDLSNKASNLRKKLGADGESSIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(19878..20039)
                     /locus_tag="ACSUUC_001136"
     CDS             complement(19878..20039)
                     /locus_tag="ACSUUC_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHQ8054355.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(20385..21341)
                     /gene="lytA"
                     /locus_tag="ACSUUC_001137"
     CDS             complement(20385..21341)
                     /gene="lytA"
                     /locus_tag="ACSUUC_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HHQ8054356.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(21717..23087)
                     /locus_tag="ACSUUC_001138"
     CDS             complement(21717..23087)
                     /locus_tag="ACSUUC_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHQ8054357.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQSLGAKRPDRIAQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(23394..24560)
                     /gene="recA"
                     /locus_tag="ACSUUC_001139"
     CDS             complement(23394..24560)
                     /gene="recA"
                     /locus_tag="ACSUUC_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HHQ8054358.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(24615..25871)
                     /locus_tag="ACSUUC_001140"
     CDS             complement(24615..25871)
                     /locus_tag="ACSUUC_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HHQ8054359.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FTLRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGNPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHVFNLVRKALLSD"
     gene            complement(25956..26972)
                     /gene="brpA"
                     /locus_tag="ACSUUC_001141"
     CDS             complement(25956..26972)
                     /gene="brpA"
                     /locus_tag="ACSUUC_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation/cell division transcriptional
                     regulator BrpA"
                     /protein_id="HHQ8054360.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNLLRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(26980..27498)
                     /locus_tag="ACSUUC_001142"
     CDS             complement(26980..27498)
                     /locus_tag="ACSUUC_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HHQ8054361.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(27488..27931)
                     /gene="tsaE"
                     /locus_tag="ACSUUC_001143"
     CDS             complement(27488..27931)
                     /gene="tsaE"
                     /locus_tag="ACSUUC_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HHQ8054362.1"
                     /translation="MYTKNEEELQALGESLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(28017..28637)
                     /locus_tag="ACSUUC_001144"
     CDS             complement(28017..28637)
                     /locus_tag="ACSUUC_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054363.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(29020..29883)
                     /locus_tag="ACSUUC_001145"
     CDS             complement(29020..29883)
                     /locus_tag="ACSUUC_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHQ8054364.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
BASE COUNT         8917 a         6673 c         5177 g         9131 t
ORIGIN      
        1 ttttagaagt aaaggtgtac tattctagtt tcaatctact ataaatttga tatgagaata
       61 gtctttctca acatccttac ccaacaagaa tgctgtagcg tccttcttaa cttgaaccag
      121 gtcaatattc tgggcttggg ctgcatagac gcagccacaa taacattgac gatagatatc
      181 atactcctca cacatctcta ctgaacgttt gtagccttga tttttcttga aatcgttggg
      241 aagatagtgg gtcgtgtaaa ttttttgcac atcgattccg atgctgttga tggtttgaga
      301 attcttatga ggactgatgg tcaaggctga accaaagtag tcaaagccca agtccatagc
      361 cacttgcgct gttttatcca gtcggtagtc aaaacaaacc ttgcaacggt cgccaccttc
      421 gggctcctcc tctagtcccc taactagttt tcggtattaa ttgggttcgt agggagcttc
      481 taggtactga accgtatttc ctgtccgctc attaaaatca ctaacaaatt tcttggtgac
      541 atagacccgc ttatggtatt ctaccttggg atggatatta gaattggcaa aatagatggt
      601 cacatctgca tacttggtca aatattctag tgtataggta ctacaagggg cacagcaaac
      661 atgcacgaga atggttggcc gttgctcatt tttctaccat acttctacca ttttctgcat
      721 gacacggtca taattaatct tctgattggg gggcatcttg cacagaattt cttctacatc
      781 gatcatgttc ttctcctttt tctagtctta ttttatcata taagttagga gagctcaaat
      841 caatttagaa gtgaatatta taaaaagaag ggttagtcat tccctccttt tgtgtttttt
      901 ataagttgtt ttctatagaa agcttacatc atcccgccca tcatacttgg atccattgct
      961 ggagctgggg ctactggttc tggtttattg gctacgactg cttctgttgt caaaatcaag
     1021 cttgctacag atgctgcatt ttgtagggct gaacgactca ctttaactgg atcaatgata
     1081 ccttgatcaa tcatgttaac ccactcgcca gttgctgcgt tgaatcctat accaagctca
     1141 gcatttttca aacgatcgat aacgatagat ccttcaaatc ctgcattgtg agcaatttga
     1201 cgaacgggtt cttccaaagc acggagaaca atattacgtc ctgttgcttc atctcctgtc
     1261 aattccaagg tagcaacagc tggaatcaca ttggcaagag ctgttccacc acctgcaaca
     1321 ataccttctt caacagctgc acgagtagcg ttgagggcat cttcaatgcg gagtttcatt
     1381 tctttcaact cagtttcagt tgcggctccg accttaataa ccgctacacc acctgacaat
     1441 ttggccaagc gttcttgcaa tttttcacgg tcaaattcag aagttgtagt ttcgatttga
     1501 gacttgataa ccgcaacacg gtgagaaatc gcttcaggat ttcctgcacc ttctacaata
     1561 accgtgctat ctttgtccac ggtcactctc gctgcttgac caagagcttc aattgtcgca
     1621 tctttcaact caagaccaag gtcttctgtg ataactgttc cgcctgttaa gatggcgata
     1681 tcttcaagca tggctttgcg acggtcacca aaaccaggtg ccttgactgc tactacgttg
     1741 aaggttccac gaatcttgtt caaaacaaga gttggaagag cctcgccatc cacatcatcc
     1801 gcaataatca agagtggacg attgctttgg agaatgcttt ccaaaagtgg caagatttct
     1861 tggatattag aaattttctt gtctgtaatc aaaatgtacg gattttcaag gtcagccacc
     1921 attttttcgc tatcagtcac catgtactgt gaaaggtaac cacggtcaaa ctgcattcct
     1981 tctacgactt caagctctgt ttccatacca cgtgactctt cgatggtgat gacaccgtct
     2041 ttgccaactt tttccattgc ttcagagatg tactcaccaa ctttttcaga acgagaagat
     2101 acggctgcaa cttgagcgat agcttcttta ttggcaacag ggatggcgtt gtttttcaaa
     2161 gcttcaactg ctgcggcaac tgccgtttca atcccacgac gaataccgat tggatttgca
     2221 cctgctgtga cgtttttgat tccttcacgg acgattgctt gggtcaaaac agttgcagtt
     2281 gtagttccat cacctgcgat atcattggtt tttgaagcta cttctgatac caatttggca
     2341 cccatatttt caaaatggtc ttccaattcg atttctttgg caatggtcac accgtcattg
     2401 gtaatcaaag gtgaaccgaa tgacttttca agaacgacat tgcgaccttt tggtcccaag
     2461 gttactttaa cagtgtctgc aaggatatcg acaccacgaa ccatggctga acgggcatct
     2521 gatgaaaatt taatttcttt tgacatactt actttctcct tctattcctc aatgattgcc
     2581 aaaatgttag cttcgcctac gatgatgtac ttttcatcgc catctttgac atcaagacct
     2641 gcgtgggctt caactaagac acgatctcca gttttaacac ttggagcaac caagtcaccg
     2701 ttcaaggtac gaacaccttg tccagtagcc acaacttgag ctgctttggt tttttcttgg
     2761 gctgagcctg caaggacaaa gcccccaacg gtttgttctt tttcttctat ttttaagacc
     2821 acacggtccc ctaatggttt caacatctga tttcctccat aatgagatag atattattag
     2881 cactctttga acttgagtgc taattcataa ttctattgta tcacttggtc agaaatagtc
     2941 aagaaaaaag tctgactttc tcaagataaa aagcctgaga ccaactcaga ctttttaatg
     3001 tttatactca atgaaaatca aagagcaaac taggaagcta gccgcaggct gctcaaagca
     3061 ttgctttgat gttgtggata aagctaacgt ggtttgaaga gattttcgaa gagtattaaa
     3121 atggcaattc ttcctcttcc aagaccaaat ctgccaaatc ttggcctgca ttattttcac
     3181 gcatggcacg ttgagcacga ctttctaaga gttggaatcc tgtcacaagg acttcggtta
     3241 catagttcat ctgaccattt ttctcaaagc gacgggtacg caattctcca tcaacggaaa
     3301 tgagactacc tttggttgcg tagcttgcca aagtttctgc tagcctgccc cataggacca
     3361 tattgacaaa atcagcttca cgttcaccgt tttggtcttt gtaacgacgg ttgacagcga
     3421 tagttgctcg cgctaccgac ttgtcattgt tggttttgtg caattctggt gtagacgtta
     3481 aacgcccaat caagataact ttattataca tattttcttc ctcctactta tctattcgta
     3541 ggaaatcaaa aaaagttaca gaaatttgta acttttcgag gaaatttctt attttttatg
     3601 aatcatgaaa cctgtcgcct gttgattggc cataatggtc atatctgtaa tctgaacacg
     3661 gcgaggctga ctggtcacat agactactgt gtctgcaata tcctgagctt gcaaggcttc
     3721 tattccttgg taaacggacg cagcccgctc tttatcacca tgaaaacgaa cagttgagaa
     3781 atctgtttcg acaatcccag gctgaatggt tgtcaccttg atatccgttg cgatggtatc
     3841 aattcgcagt ccatccgaaa aggtcttaac cgctgccttg gtagctgagt aaacagcggc
     3901 accagcatag gcgtagattc ctgcggttga ccccatattg ataacgtgac cttgattgac
     3961 ttttatcatt gctggcaaga aacagcgagt aaccgccatc agacctttaa cattggtatc
     4021 caacatggtc aacatatcca actcctcata gtcttgatag ggagccaagt caagagccag
     4081 tccggcgttg ttgaccaaga tatcaatcct ccctatcgtt tctagaatat cagagcaaac
     4141 agtcttcacc atgaccatat ccgtcacatc tagtggaaaa gtccagacag tttgatttgg
     4201 aaagcttact gcaaactccg acttgaggat ttctaatctg tctatccgtc gtcctgttag
     4261 aacgacatcc tcaccctgct ccagataagc acgcgcaatc gcttcaccga ttcctgaggt
     4321 tgctcccgta atcactacat tttttgccat cttatttcct tctatcagat gctgacaagt
     4381 tcctaggcag tccagtgttt cgctgggtcg aacggtgttc cgacaacttg gtcttctgat
     4441 aattcaagca ccccacgttt ttgcggagca tttggcagat gcaattcacg aggactgcac
     4501 atcataccaa aactcttttc accacgaagt tcacctggga aaatgagatt cccttttggc
     4561 atcatagctc caggaagcgc gacaatggtt ttcaacccca cacgcgcatt gggagctcct
     4621 gcaacgattt gtacagtctt atcacttgcg actgcaactt ggcagatgtt gaggtggtca
     4681 ctatctggat gggctaccat ctcaacaatt tcaccgacaa caaacttagg ttccttatca
     4741 ttaacaattt cttctgtaaa accttccgcc tgcaactctt ggttcaaacg agcgacttgc
     4801 tcatctgtca aaaagacttg accgcgctct gcaatttcaa ataaacttga aacttcgaaa
     4861 atattccaag ccactgtttc cccattatct ttgagaaaaa cacgggctac cttgcctttg
     4921 cgctccacat ccagtttggc atctccgcta tttttcacga tgaccataag gacatcaccg
     4981 acatattctt tgttatacgt aaaaatcatt gtttcctttt tctcctattt caatcctgct
     5041 aaaaaatcat tgatttgttg cttgctttta cggtcgcgat tgacaaaacg accgatttcc
     5101 ttgtcctttt ctagaacaac aaggctagga attccgtaaa catcccagag tttggccaaa
     5161 tccatatact gatctcggtc cattcgaata aaggtgaact ctggattggt ctcctcaatc
     5221 tctggtaagg caggataaat ataacgacaa tcgccacacc agtctgccac aaaaaggaag
     5281 accttcttgc ccgctttttc cactaaagat gctaattctt ctaaacttgc tggctgtatc
     5341 ataagacttc ctcctcatag actaggtctt cattttcata gataaaggta taatgacggc
     5401 catcctcaaa aatgacgcca ccaaccaagc tctccagact gctttcgtaa acttgaacat
     5461 agagggtcgc aatttccccc atgtcggaaa aaaggtctcg cacaatctct gtcaactctt
     5521 cctgagtctt catgagctta cggtcatctg caactttttt cgtagcaaga gcaaggcttc
     5581 cgatacctag cagagccaag cctgccatcc acattttttt agctttcata ccattcattt
     5641 taacacaaaa aaggcttcag gacaaatgag gaagcagcag aaaagcaagt aaaaagcctc
     5701 ttcctttaag gaaaaagact tcttatacta agagcaaact aggaagctag ccgcaggctg
     5761 ctcaaaacac ggttttgagg ttgtagataa ggcgacgttg acgtggtttg aagagatttt
     5821 caaagagtat tattcttatt gccaggcacc taagttgcca acgtagtaac tatcaggtgt
     5881 gtaggtattg cgaagcatct tacctgatga agccagataa tactacttgc cattgtcttt
     5941 gacccaatca ttcgcaatca tggaaccaga agaacttaca taataccatt ctcccttgtc
     6001 ataaacccaa gtactgactt tcatggttcc tgagcaatta aaggcaaaaa aactgtccaa
     6061 tatcattcgt tttttaaaag catttgacac tacatcatct acgctgtagt acatagatac
     6121 atcaaacgta aaagccaaaa tatcgaaaaa tatacaactt ttaaaggcag catttcattt
     6181 tttaaagtct aacaaccata gaactgaaat cagagcaagg catcaatttc ctactcttag
     6241 tacgtctatt ttgatggttg aagtgaagat ttttttattt aacgtagaca atttccaact
     6301 tcccaaaagc cacatctcca cggatagtca aggttttgct ggttggggct acaggagcgt
     6361 cagccttagc tgcaccaaag gaggtttcta ctttcaaatc tacacgccag tgttgtggaa
     6421 catagacggt tgcattcccg aaggccactt caatatttaa agttgcaaaa tcacctagca
     6481 tctctgcatt atcatagtag attttagcat ccccaaaagc gacttccact tggtcatcta
     6541 cgagatcttg atcttgctta tagaaggtcc cgctaccaaa agcgacttcc ttatccgtga
     6601 cgactgtttt tttcccattg taccaccatt ttttttcatt ccagaactta cttgaatgcg
     6661 tcagataacc aacaccaagt accaccaaga tgctagccca aataagagaa tgattggtaa
     6721 ctggtaacaa gtcataagcg taatttgcaa tgatgagcgc cagtaaacct gtaaaaactg
     6781 ccgaagtgag atgacgtcta aggatggact caatggactt ataagcaaaa aaaacaatac
     6841 ctagtaaagg ccatatttta ccatccaaag aaggaattcc aaaattccct tgcagcaaga
     6901 tccaagctgc taaaaccaac aaaacaatac caaatgcttt ctttttcatg ttttttacct
     6961 catgtttctt agattttctt ttaggaggga ttggtaatgc cgtgagacat gaacctcctt
     7021 gtgcgtctga taaaaggaaa tggtgcccgt tcctgaaaag gacttgtcca ctgagtaaat
     7081 ctgacggatg tttgcgatcg ttgacttgga aactcgatta aaatagcgag gcaagataga
     7141 ctccaactca tagagcttga ggcgaacctc ataagcttcc ttctggttat gagcgtagat
     7201 cttgctccct tctgtttcaa agaagagaat ttctgacagg tctagataat attcacctgt
     7261 ccccttgtaa aaagtcaacc tcggagcctt tgactcttgc aagagccgtt gcaagtctgc
     7321 aatttcatct gtcaaagtgg gggtcttgat gacaatttca gtctcctcta aattgccgtc
     7381 aatctcaatt cgtaacttca tcacatctcc tttctgactc tactatatca aagctaagtt
     7441 aggaatacaa gggcaaaaaa gcaagtggtc aatttgaagc agtaagtggt tgtaggacta
     7501 gcttaactta catgtaagaa taggaagaaa aggaatcccc acaccaaacc acaagcatag
     7561 ccaaccaaga catccttggg ataatgaaca ccccctaaaa ccctcaccaa ccccagcaaa
     7621 gctgaaaaga tcaagcatac taagccaata ggtagactag catgcagaca ggccatggag
     7681 atgatagttg ccgaaaagac atggcgactg ggcatcgacc gtcccgaact atccttatca
     7741 agaaggggac agatatccca agtttcataa ggtctcgggt gattgatttt cttacgaaac
     7801 agggacaagg ccacaaaacc tgatgcagga ataagcacac aaaccccaac ttgctgacca
     7861 agtcctagtt gcaggtaagt ggtgactagc aagatcagat agaccagggg catggcgact
     7921 gtcatcaaac gattgaaact gcgtaatagg aataaaagaa ttggacgact agttagtctg
     7981 gagctgatat ttcgatacca ttcttgataa tttttcattt atgcttctca tacttttcta
     8041 gaacttgttg agatgttttc cccttggcaa gccaatccac tagcttgtcc aagcgacgta
     8101 tttcctgcat cagaggatca tcaatttcct caatacggac actgcaaatc ttccctgtaa
     8161 ttgcaattcg ttcagggaca taatatggtg cttgtctaaa aaaatctccg taagtaacat
     8221 ccctatccag acaagcaaga acatcactca cttcataccc tgtcaaccaa ctggtcactt
     8281 ggtgaactga ctctgccttt ccaccctttc gctcaacttt tgcaatcaag gctaagtaga
     8341 cagcagcaaa tttcatattg tataatttct gactcatact tctctctttc tatgtgtact
     8401 agtataaata agaaaaagaa ggccgtcaag ccttcttttg atttattctt ctgcttcatc
     8461 ttctgtaaat tgactattgt acaagtcagc gtagaagcca ccttgcgcca tcagttcctc
     8521 atagttgcct tgctcgatga tatttccatc tttcatgacc aagatcaagt ctgcatttcg
     8581 gatggttgac aagcggtggg caatgacaaa ggatgtgcgt ccttccatca aacggtccat
     8641 ggctttttgg atcaattcct ctgtccgtgt gtcaacagaa gaagtcgcct catccaaaat
     8701 caaaagcggt gcatccttaa gaagggcacg agcaatagtc aatagttgtt tttgtcctac
     8761 agacaaggtc acggtgtcat ccaagatggt atcatagcca tctggcaagg tcataataaa
     8821 gtggtgaatt cccacagcct tactagcttc catcattcgt tcatcactaa tccctatttg
     8881 attatagatg agattgtctc gaatagttcc ttcaaagagc caggtatcct gcaagaccat
     8941 tgaaaaggca tcatgcactt ctgaacgcgt catagccttg gtatccacac catcaatgtg
     9001 aatacttccc ttatcaatct catagaattt catcaaaaga ttgacaatgg ttgtcttacc
     9061 agtcccagtc ggcccaacaa tggcaacctt ttgaccagca tgaactgtcg cagagaagtc
     9121 atagtcttga acattgacac cgtccaccag aatttctcct gctgacacgt cgtagaaacg
     9181 tggaatcaga ttgaccagag ttgatttacc agaacctgtt gacccaataa aggccactgt
     9241 ttgaccagtt tctgctttaa agctaacatg ttcaataact gcctccgaat ttgccgcata
     9301 gcggaaggtc acatccttaa actcgacctg acctttgaag ttttcatcag tcagctgcac
     9361 ttgaacaggg ttttggatag aagaatgcaa atctaaaact tgattaatcc gcttagcaga
     9421 gaccatagtt tggggaagaa cgatgaagag tgctcccatg agaaggaagt ccatgacaac
     9481 ctacatggca taagacatga aaacaatcat gtcactaaag agaggcagac gcgctatcgg
     9541 agcagcgtcg ttaatcacat aggccccaat ccagtaaatc gccacactca aaccacttga
     9601 aatccccatc atgataggat tcaaaatagc cataagacgg ttgacaaaca aatttaaacg
     9661 ggtcaattca tcatttactg ctgcaaattt ttcattttga taatcctctg cattgtaggc
     9721 acgaacgaca cgaatacctg ttaaactctc acgagtgata ctgttcagtt tatctgtcag
     9781 cccctgaatc aaggactgtt ttggaaaggc tagcgtcatc aaaacggtcg tcatcaggac
     9841 gttgacaatc actgccacaa gtacggccca gagccagtat tctgaatgac ctaaaatctt
     9901 cccaatagcc cagatagcca taattggacc acacgttacc acttgcaagt ccatagtaat
     9961 caacatttga acttgagtaa tgtcattggt agtacgcatc aagaggctag gaattgaaaa
    10021 tttcttaatc tctgtctgcg agtaatccaa aactcggtta aaaatatcac ttctcagcct
    10081 actagtataa gaagccgcca ctcgggatgc aaaaaatcca actgcaacta cggacaagaa
    10141 ggcaagaaag ggcattccca tcatcatgct tgccggctgc cacaactcat ctaaattagt
    10201 tccttgacta cctagcaaat ccgtaatttt cgagatatag gtcggcactt ccaactctag
    10261 atagaccgaa aagcaagtaa agagaatggc tagtaaaatc atcccccatt cttttctact
    10321 aattcttttg actaatttct ttattctctc ctcctattcc cttgatattt gcctgtagtt
    10381 gaccgagaac tttctcaaaa atcagtaatt catcttcatc aatgtcttcc atcaactgct
    10441 tgtctatgcg ttcaaaaaaa gccttaacct gttgcatctg agaacgtgct ttgtccgtca
    10501 gacgaacaaa cttagcccgc ttatcaacag gactcgcctc caattccacc aaaccatttt
    10561 gcactatacg cttaaccaga ttactagcaa cagacttggt aatattgagt tcctgctcga
    10621 tatctttaat caagaccaag tcttggtttt tctcgcgatt atccaaaaaa tgcacaacct
    10681 gaccttgcgg cccacccata aattcaatgc cgcaacgttt ggcttccttt tgcaccatca
    10741 ggtgaatttg atgaccaaaa cgcttaaaga ctaacatcgg tttatccata atctccccct
    10801 tctaaataaa aatagttctc tggagaataa ttaaatttct atgagaacta ttttcttgat
    10861 taaaaaaatc ccaagtgatt ttctcactta ggatcatgtt ctataggtta aattaaaacc
    10921 catctacgtt cgtataaatc ttttggacgt cttcgtcgtc ttcaagaacg ctgtaaagtt
    10981 tttcaaaggt ttcaaggtct tcgcctgaca attccacttc tgactgagga atcatttcca
    11041 attcagtcac ttggaattct tcaataccag actcacggag ggcaacgata gccttgtgaa
    11101 ggtcagttgg cgctgtgtaa actgtgattg taccttcttg tgcttctacg tcatccacat
    11161 ccacatccgc ttcgagcaat tgctcaaaga ctgcgtccgc atcttcacct ccaaatacaa
    11221 taacaccttt gttgtcaaag aggtaagaaa cagaacctga agcgcccatg tttccgccgt
    11281 ttttaccaaa ggctgcacgg acattggctg ctgtacggtt gacgttagaa gtcaaagtat
    11341 ccacaattag catagagcca tttggcccaa aaccttcgta acgtccttct gtaaaggttt
    11401 cgtctgtgtt tcctttggct ttatcaatcg ctttatcgat aatgtgtttt ggcacttggg
    11461 cttgtttagc acggtcgata acgaatttca aagctgagtt tgattctgga tctggatcac
    11521 cttttttagc tgctacatag atttctacac caaattttgc atatacttta gagttggctc
    11581 catctttagc cgttttcttg gctacgatat tggcccattt acgtcccatt aggaatctcc
    11641 ttttttcaca ttttaatctt tcttattata acacaagttt ttttgatttt cactagagga
    11701 aatggatttt attagcaaat caagctagga tagcacttta cctgctaaga tggtcttgcc
    11761 tttctatctt tatcaacaga cactcatcca cattcaaaaa acaaactaga ccattatctg
    11821 caaatagaaa gtttcagcca agtttgacaa agtcagctca aattactgtt tgaagtttgt
    11881 agatataagc gacaaaaaca atcatactgc accttttgtt gacagtctac tccagacata
    11941 tcatagttca agtaaatact ttgaaatcca acagttctta taggcgctat tgtattctaa
    12001 gaaatcaata gaagagtttc taagcaaacc tctaatactc aataaaaatc aaagagcaaa
    12061 ctagaaagct agccgcaggt tgctcaaaac actgttttga ggttgcggat agggctgaca
    12121 tggtttgaag agattttcga agagtataat ttacgtgttc ctaagatgga gaagttagac
    12181 tagtacactg gcacttctaa accattgcta gcaattgatt tgttcatatt taatttcatt
    12241 ttttccataa atgggtatta gatataaaca gcaaaatatt tccgatacgt gtcattcttg
    12301 aatttccaat catctaaaac aagtaaagga taatcaatcc cctgtatatc aaggaattgg
    12361 ctaccctttt tactttttta cacatcctgt ttgatagact cattttaaca tcacgagcat
    12421 actccaatgg aaatcgctag gcaagagata aactttcaga tattcgcaga gagctcatcg
    12481 cctctttttg tcgcaaacat tcttctctcc taatcatttt ctaccttatc ctctacctga
    12541 ggatagagag ttgttcccca aatagaaatc gtccgcttac gcactagtgg caaatcggtt
    12601 ttttcataaa ccgtacgcca ccattcccag gcaagcccgg tacactctct aattttgaca
    12661 gagagattgc gaacattccc ttttaaagga atactagtgg taaagtgagc cgtcaaatcc
    12721 tgcccatttc tgtcccaagc cttaggagtc aagacttcct tgccttgatg atcataggat
    12781 aattcatccc aagtaatata atattgagca acataggcac cactatgatc cagcagtaaa
    12841 tctccgtttc tgtaagctgt aaccttagtc tcaacatagt ctgtactgtt ttgaaaggtc
    12901 gcaactacat tgtcacgtaa aaaagaagtt gtataggaaa tcggcaagcc tggatgatcg
    12961 gctgtaaagc gactgccttc ttgaatcaag tcctctacca tatccacctt gcctgttaca
    13021 actcgggcac ccgaacttgg gtcgccccct aaaataaccg ccttcacttc tgtattgtcc
    13081 aaaatctgct tccactctgt ctgaggagct actcctttta tcaaagattc aaaagcagcc
    13141 tctacttcat cactcttact cgtggtttcc aacttgagat agacttggcg cccataagca
    13201 acactcgaaa tatagaccaa aggacgctct gcagaaattc ctctctgcct taaatcctct
    13261 accgttacag tatcttgaaa cacatctcct ggatttttaa cagcatctac gctgactgta
    13321 taataaatct gcttaaaatt aacaatctga atctgctttt cgcctgaatg gacagagtta
    13381 aaatcaatat caagagaatt ccctatcttt tcaaagtcag aaccaaactt gaccttgagt
    13441 tgttccatgc tgtgagccgt gattttttca tgctgcattc tagctgggac attattgacc
    13501 tgaccataat cttgatgcca cttagccaac aaatcgttta ccgctccgcg aacacttgaa
    13561 ttgctggggt cttccacttg gagaaagcta tcgctacttg ccaaaccagg caaatcaata
    13621 ctataagtca tcggagcacg atcgaccgca agaagagtgg gattattctc taacaaggtc
    13681 tcatccacta cgagaagtgc tccaggatag aggcgactgt cgttggtagc tgttacagaa
    13741 atatcacttg tatttgtcga caagctccgc ttctttcttt cgataacaac aaactcatcg
    13801 ggtagctgat taccctcttt gatgaaacga ttttcaatac tttctccctg atgggtcaag
    13861 agtttctttt tatcgtaatt catagctagt ataaagtcat ttactgcttt atttgccatc
    13921 ttctacctcc taataagttc ctggattgag ttgcataaac tcagacttgt tcagcgaaat
    13981 cagccgtggt tggactaagt aatccaaaat ttcctcgtac aattcttctg agacattgcg
    14041 tcgccgtctg gctaaataag aagtcggaat gaccgtatta tccaacataa ataccttatc
    14101 taagtcaatc aaggttggtc ttgtaaaagg attacgagct agatccggct cttctatcat
    14161 aaagttcttg accaaacgtc tggtcaagag agctggtttg aaggtctgat ttttaaccaa
    14221 ctctttgttt ttagtcatgc tgttgtcaat acagatatac atatgattct tcacagccaa
    14281 atcgctacta atagtcggaa aaggcaaata aagagctaca acatctcctc tcttaatcaa
    14341 gcaagagcac ccccttttct cctaatgtaa catagacagg attgaccaag tcttctgatt
    14401 gactcagaat ttccaaagtt tgagtttggc gcgctgtcaa tttagtagca tcttgtctct
    14461 tcaatacaaa atgcttgtcg ccaataacct tgacaatata atccttctcc aaagctgact
    14521 ggtaaatcca catcagatgt tgtctgtcct gagaactcaa gagagaagga ttttcaagcc
    14581 tcccgatagt ctgataaaaa tcaaaaacag gagctaactc ctgccaatct gattggctag
    14641 ttgtcaaggc tagaaaaagg gctttgcgag ctgatacttc ttggttagcc ttgagagtta
    14701 ctttcccctc caagtttttt agaaatcggg aaactccaga aagcaaattt ttctctaact
    14761 gcgagaaata aaaacctttc gttcccagac ataagtcttt catgtcgctt tctctagcaa
    14821 ataagagctc aaacatttga tagtaaaaga aaaatatctg gcactgggtc gcgctcatct
    14881 tttccttatc ggcttctttt tttaaccaga gcaagggcga caggtagctg gattgagaca
    14941 tttcctctac ctcctactct tttttaactg gagcatctgc actagctgcc acttcttttg
    15001 actggatact ttcccactgg ttaatctcct ctgagataag accttcgcat gtcttgacaa
    15061 atagggcaaa agccttggtc tttcctgcat atttctccgt ttggcattga tagaggaatt
    15121 tttctttctc caggagttgc gcagtttttt ggtaagaaat ccaattttcc tttgcattat
    15181 acaaattgat aatcccctca cacagcaagc cgagactgga taaggcaacc gaaatcaaac
    15241 ggtagcgatc acctggcata ggaatagcac aaaagacagc tatgaggaaa cctgccacga
    15301 tttctgttat ttttaatacc ttatagcgcc tacgatgttg aacgcttttc tttaaaaaat
    15361 gagctatctg tacgtctaat cgctctgtca ggtacatttc ttctggcgtc atattcgtaa
    15421 ctcctttcat ttactttgat aaccatagta taacatattt gaatatcaaa gtatagtaaa
    15481 aactggacta taacttatta gactccctgc gaaacaaaat atggtatagt agttctatga
    15541 attatgaagc aagtaaacaa ttaactgata cacgatttaa gcgtcttgtt ggtgttcagc
    15601 gtaccacttt tgaagagatg ttagctgtat taaaaacagc ttatcaaaaa agtcggacaa
    15661 gctggtaaaa tcttggctga cagtggttat caagggctca tgaagatata tcctcaagca
    15721 caaactccac gtaaagccag caaactcaag ccgctaacag ctgaagataa agcctataac
    15781 catgcgctat ccaaggagag aagcaaggtt gagaacatct ttgccaaagt aaaaacgttt
    15841 aaaatgattt caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg
    15901 attgctggta ttatcaatca tgaactagga ttttggtttc gcaggaagtc tattatatat
    15961 gcacagacat atgaaatctt tttgagacag cagttatgat atatttatcc attcacaaca
    16021 tcttctgtac taatactaca atattggtac attttgatta cacaatcgtt tcaaaaaata
    16081 tgatggaagc ctgagtattt tatagtaatt cccttcctat caactagatc aaccagttga
    16141 gtgttgaatg ttgaaacacc ctagcctcag caaaggacta tgatcagcat ttcctagcca
    16201 ataggacgct ccaaatcacc tattctaagt ccatcactag cttggtcagt aagatacaga
    16261 ctgcaaggcg agactgacgt ggttgatgag attttggaag agtattacaa tcatagattc
    16321 accagtagac ttgaccgcag atttaactat agtagattga aactagaata gtacatctct
    16381 gcttctaaaa cattgttaga aatcgatttg actgtcctga tcaatttgtc ctgttctcgt
    16441 ttcatttcac tatactaaaa aaccacctga aacaaatcaa gtgactagag gataaaaaca
    16501 aagactaggc aaaaagtttt gaaaagcaaa aaacgcataa tatcaggtct tgaaaaacct
    16561 tgatactata cgtttgattg tgggaagatt gacttcattt tctcctgaaa ttgaagtttt
    16621 ttctagtttc cagatataga cgaattcaat atagccatct cgctacaatt attttaacca
    16681 tcgagaaaat ttttcagaat ttcaaaaatt tcattttgat ccaatgaaat gtcatcattt
    16741 tgaagaatag ttgacttcac aggctctaat tctatcacaa agcggtgtat gtctgctttt
    16801 accgcactac ttgatgttat agccgataac ttttcatctc ctagcaagga agctgtcaaa
    16861 cgggtaaggt cattcaaatg ctttttaatg gacttactta aaccttgagc acctgtagca
    16921 gagcgttccc tcatatccag ccaagcttta gccttaaaaa taattaatac tcaatgaaaa
    16981 tcaaagagca aactaggaag ctagctgcag gctgctcaaa acactgtttt gaggttgtag
    17041 atggaagctg acgtggtttg aagagatttt cgaagagtat aaaccacaat tactcaatac
    17101 cgaatacccc tgaatggttt ctttttcatg caccaatata ttataataat cttcatccaa
    17161 taataaggct gataaactgg catcttggtc aaaatgtaag ggaatttctc gaccgtcctt
    17221 ctttaatgga tattctggta agatactaaa tagttcaatc atagaaggaa actcaggatt
    17281 agttgttgta aatcgaaaaa gctgcgcttt ctcatctttc tgacttcctt gatactctcc
    17341 caattctaaa aaatgattca aggtagtata aaattcctta ttttttactt cataaatgat
    17401 gaccatatca taatcttttg ttgtgcgact tttaaatcct tgcgaatcca atacgataga
    17461 ggtagcagtt cccccaatca gaacataata gttctgaaaa tccgcaaaca tttcttgaaa
    17521 aataactttc gtattagctg gcatcatctt ctcccagata ctgtaatatc atattttcta
    17581 gtgcttcact ctcttcctct atacgtgggt catcatcatc ttttaaggtc aaataaagag
    17641 aaatcggatc tacaaattgt ttatcatgat tatttttaaa atcattccaa aactcagata
    17701 caaaaggacg atatttccat atctctagca tctttccttt taaaacatgc tgagaaagtg
    17761 gcaaggataa ctgattgaat tttctctgcc atatgacata gctagtattt tcatccgttt
    17821 cagctaaaaa agttgaatgc gacaaagcat aagcaccacc atatagaagg ttagaaacag
    17881 attttatctg ctttatatcg ccatctggca ataaaaaggc aatccacgtt aattgttcgc
    17941 taggtgttaa ttccttaggg atttcagtat cattcgcatt gagtactagt cccaatggag
    18001 ggaagaagag gtttccctta aagtctacaa acggaactct agcttgaagt aattgctttt
    18061 tttcactgtc tgataacttc gaaaacacca aaacaacatc catattggct ttttcaccca
    18121 tagtgcgagc ctgagtaaca aatgaactca aactccccct tctcttttct ttaatcaata
    18181 aaaatgattc cttatgaaaa gtcatttgag tatactcaaa cctttttaca aaactgattg
    18241 gtaaagtcaa agtcagttcc tcaatactga catcaacata aaaggattga aaaattgaca
    18301 ttatcttttt gacattcatg ttttttcctt attctatcat ttttattata ttttatcatt
    18361 cggtataata aaatataagt tttttgataa aataaccaaa aactactcgc tatcccctct
    18421 cacattaccc tacatatcgt ttgacatgcg actgatagtt caggaaaact tcaaggagaa
    18481 cttttctctc atccactatg caggacttac tatttcactt ctactcctat aggctcaatt
    18541 tgacactttt ctttttcgaa ttgctcatat gcctcctgaa tagtgagttc gatttatcca
    18601 aatttatttt tgtctatttt gatgaatact tccacgaaga tagtctgaaa atgaatttgc
    18661 accaattttc cttctctttt taagcatatt attccagata tgattgccct cttgttcagt
    18721 aataaattac gctttaaacg cttcaatcag tatatctcct gttgtcatat gttctaaaga
    18781 aaattcttct acatatggtt taacatctct taggttatta cttcctaata tcccattatg
    18841 ctttttcgct aagaaaatag aagtcgcttc tcccttacca ataatcttgt tactatcatg
    18901 atttcttgtt aaatctctat ataatgcgta ttcttcagtt ccaatgtcta tgctcacaat
    18961 ctcagctgaa cccttagtta ccaactggtc tatcctagat tttaaatggg gaattgtagg
    19021 tatattgatt tcatcataca cctcttgtgg aataacaatt ttacccgaat agagcttttc
    19081 taaaagatgt tcagtgccaa cccataaaaa tgctgaaata caatctgcat caataaatac
    19141 acgactagtc aaacgacaac tccccctctt catctagccc atatacaata tcatatctga
    19201 aagcatctag taacagttcc tcatacttcc cttgcgaaat tctgttattt tctaaaagtt
    19261 gttcagtcga tttaatatag tgtcctaata ccatttcctt tttactttct gacaaaggac
    19321 gatataaact tgtatcatag cctaatcttg aagctgtctc tataacacta atatccatat
    19381 ttttaatttc ttctgcatca aggtatccat catttctcaa tctatataac atagctttat
    19441 gactgatacc ataaaactga cccaatttta taatatcttc tacttcaaga tgagttctat
    19501 tggcattttc tctgatttcc tcaaccatcc tatacagtga agatgggaaa attaaaaaat
    19561 aagaagcaaa ctgatccgct tttctttcag tttcatctcc ttcaccaatc aagataagac
    19621 tgactgaact cttcttcacc tcatcataat aaagatgata cagtccatgt gctaaagaaa
    19681 atctttacct tcctaatggc atgtctgaat tgactgcaat gagactgaac tgagttcctt
    19741 tataacagac tccgctaata ttctttccga gtccataaaa taccagcgtc aaattttcta
    19801 tcttttgtac caatttaaaa atatctatcg acgattcacc atcagctccc aacttttttc
    19861 taagatttga agctttatta cttaaatcca ttcgtgatat tcctttcacc tttttccatt
    19921 ttggcaatca tgctttgatt caaagacaaa tactcagcaa tcttatcttg agtaagattt
    19981 gaagatattc taagttcttt tattcttttt ccaacatcac atacatttat catattcata
    20041 cacctctcat aaaaagaata gcacactctt gtcataattt tttaaataaa aaaattatga
    20101 caaaacaagg aagcaattta ttgatgctgc ttaaaaatct aaaattgatg agttcctatc
    20161 aaaaatcgta tcttcaacct caaaacagta cttaaagcta tccgactcgg tttacattgt
    20221 caaatttaga ttttatttga gcataacttt ctagttcgct ttctgatttt tgtttaatat
    20281 agtagcaaac attgaaggaa atatctccac aagaaaacgc atactattaa gctttttcaa
    20341 gacctaataa tatgcgctgt tctgatttga aagacattcc attattattt tactgtaatc
    20401 aagccatctg gctctactgt gaactctggt ttatctgcca gtgttccgtc tggtttgagg
    20461 tagtaccagc ctgttccgtc cgctgactgg ataaaggcat ttgataccat ggcgccttct
    20521 ttagcgtcta agtagtacca agtgtccttg tacttgaccc agcctgtctt catggcacct
    20581 tctacatcaa aatagtacca cttctcagcg attttcttcc agcctgtagc catttcgcct
    20641 gagttgtcga accagtacca gttgccgtct gtgtgcttcc tccagcggtc tgcaagcata
    20701 tagcctgaac tgtcaaagta gtaccaagtg ccattgattt tctcaaactt gtcttttgga
    20761 taagagccgt ctgaatgtac gtaccagtag ccagtgtcat tcttctgcca gcctgtttca
    20821 atcgtcaagc cgttctcaat atcatgctta aactgctcac ggctaatgcc ccattttgcc
    20881 aagtaagggt atggatccac atggtctgag tggttgtttg gttggttatt cgtgcaatac
    20941 tcgtgcgttt taattccagc taagctccct gtatcaagcg ttttcggcaa acctgcttca
    21001 tctgctagat tgcgtaagag ttcgatataa aggcggtagt ccgtcatgaa ctcttcttta
    21061 gttgaatggc tttcaatcag ttcaaccgct gcataggtct cagcattcca accgccccca
    21121 acgtcccagg caccattatc aacaggtcct acctgcatga tgcaaccgtt cccaacaatg
    21181 tgcgagaaaa aacctaattc tgggtctttc cgccagtgat aatccgcttc attctgtacg
    21241 gttgaatgcg gattcccagt tgagtgtgcg tgtacttgcc tatatggttg cacgccgact
    21301 tgaggcaaat ctgttcttaa tttactcaca ttaatttcca tattctactc cttatcaatt
    21361 aaaacaactc attttttaca atccagaacc agaaactcct ttatttctac cttacaaaga
    21421 agacaatctt agtcacgatt aggcttgtag atagaacctc aaaacgcact attttgacac
    21481 tgtaaatagg actgacaagg tctgcattct atctacaata acaccccaga ctaaaaagct
    21541 tttcaaaagt atatttttac agtctctata tgtccttttc ataaatacta tactttatta
    21601 tatcatataa aagaagtcaa aagtctgtta aactattttc aacaccaaac taaagaagag
    21661 aacacaagtt ttttcgatgt tcactagagg aaatggattt tattcagtaa atccaactag
    21721 gattgcactt tggttgccaa aattgccttt ccttctttta tcaagggatg acggaatagt
    21781 gagaagtaca gttgaactgt catggcaacc cagataagag gttcacaaag gataacaccc
    21841 ttatatcctg cccaaggaat aatcaaaacc acaaaaacga tttttccgat tagttcaata
    21901 aagctagaaa ctagaggaag gatcttttgc cccaagccct gcaagcaatt gcgataaatc
    21961 aacaagaggc tcaaaatggg ataaaaggct gaactgattt gcagatagag acttccattt
    22021 tctatcaagt aaccatctgt cgaactagcc aagaaggaaa ccaaggctgg actggcaaaa
    22081 aagaggaaaa tacaaacaaa aactgcccag gatatactta aacgactgcc gattcgaaga
    22141 ccttgagcaa tgcggtcagg tcgcttagct cctagactct gagaagcaaa ggtcgtcatt
    22201 gatgcagaaa tagcggtcat aggaagaagg gcaaaggtca taatgcgtcg agctgccgtc
    22261 tgagcactaa taatcactgc accaaatgta ttaacagaag actgtaaaat cacactgccg
    22321 atagatacaa ttgaactcat caagcccata gccaaacctt gctccaagag atccgcgtac
    22381 aagcttttgt cccatttgaa atgtttaaac cgtggcaaga gttctggcac acttttacga
    22441 atataataaa agcagagaac cgctgataaa ccttgtgaaa taatagtagc aagtcctgcg
    22501 gattgaactc ccagatgcaa ttgcgtaata aaatagagat ccagaaccac attaaccaag
    22561 gcagagaaaa tcagaaatcc cagggctgct agactgtcac caatagaccg caacaagcct
    22621 gcaaaaagat tataagcaaa gctgacacct acacaggtca caatcataga aatatattga
    22681 taagattgag gaagaatttc tgcaggagta tctaagtatt gcaagagagg atacaagcca
    22741 agaaagccca gcaacataac tagaatgctc aaaagagcac ctaaaatcca ggtggctgct
    22801 actgcttcct tgattttagt gaaattccga gccccataat aacgagcaat gacaatcccc
    22861 atgccattgc caacaccaag tgtaaaacct acaatcaggt caaaaatcgc tgtcgtcgct
    22921 cctactgcag ccaaggattc ttgaccaaga aatcgtccaa caatcaagac atcagcagtg
    22981 ttatagagct gttgaaaaat atttgatagc aagattggaa aggtgaagct taagagcgag
    23041 ggaagaatcg gaccatgtat caggtccact gttcgttttt tattcataaa gctattatat
    23101 cagctttcca gaggagcgac aagaaacagc aaacttatat atagcggaat gaaataagga
    23161 aagtcaaatc gatttttaac aatgttttag aagtagatgt gtactattct agtttcgatc
    23221 tattatagtt ggttgagttt ggaatagtac gctgtagctg ctaaaacatt tctagaaatt
    23281 aatttgactt tcctaataga gttgttcata tcttatttca agctactata tataatctaa
    23341 aaacctgaat caaaaatcga aaaagtagcg gatttctcca ctgctttaac agcttattct
    23401 tcaatttcga tttcaagttc atcgcctaag tcaagcgtaa cttcttcatt cactgcttct
    23461 tctttctttg gctcatcttt tttgttttca gtatcttgtt ctgaaacttc ttctccatca
    23521 atcaagccaa atttagaacg gacttgctta tcaatttcat caaagatttc tgggtgctct
    23581 gccaagtatt tcttagcatt ctcagaacct tgcccaattt tttcatcttt gtaagaatac
    23641 caagcccctg cttttttgat aatatccaaa tcgcttgcaa tcttcaaaag ctcaccagtc
    23701 ttagaaattc cttctccgta cataatttca actacggctt ccttaaacgg tggagctacc
    23761 ttatttttta caaccttaat cttagtttct ttaccgacat tggtttcttt ttggtcacca
    23821 gttcccttaa tttgtgtatt accacgaaca tccaagcgga ctgaagcata gaatttcaaa
    23881 gcacgtccgc ccggtgttgt ttctggattt ccaaacatca ctccaacttt ttcacgcaat
    23941 tggttgataa aaatggcaat tgttttggtt ttattgatag aggcgccaag tttacgcatg
    24001 gcctggctca tcatacgagc ctgcaaacca acatggctat ctccgatatc tccatcaatt
    24061 tccgcacgag gaacaagggc agcaactgag tcgactacga caagatcaac tgcacctgag
    24121 tcaatcaatt ttcccgcaat ctcaagacct tgctctcctg agtctggttg agacaagagc
    24181 aattcgtcaa tattgacacc aagggccgca gcataagctg gatcaagggc atgttccgca
    24241 tcgataaagg cagcaatccc accttctttt tgcgcttgtg caactgcatg aagggcaacc
    24301 gttgtcttac cagatgactc tgggccatag atttcgatga tacgtccctt aggataacca
    24361 cctgagccaa gggcaatgtc aagagctaaa gaacctgagc tcatcacttg caccttttgc
    24421 tccgcacgtt cacccaaacg catgattgat cctttaccaa agtctttctc aatcaattta
    24481 agagcgtcat tcaaggcctt ttcacgttct gccccaaatt tttttgaaat ttcttctaat
    24541 ttttttggtt ttttcgccat tctattctcc tacattctaa tgatcctcag acctatctac
    24601 tattatatca aaagttagtc acttaataaa gccttgcgaa ctaggttaaa gacatgcata
    24661 accgcaatgt gacgtacatc tgctcggctt ctgcctccaa tattaacctt gataacctca
    24721 gttccttgat cttgcgccaa gcctatgaag actgtcccaa ctgggtttcc ttctaggcta
    24781 tctggtcctg ccactccagt caaactaatt ccaaaatcag actgggtctt gcttcgtgcc
    24841 tgctcagcca tcttctgagc tgtaaattca gacaccacac catgttcttc caaattcttg
    24901 gcaggaatat ccaacatcct tgatttttcc tccaagctat aggtcacaaa accgccctta
    24961 aatatacttg aaactccaga aaaattcgcc acggtagctt ggaaaagacc tgccgtcaaa
    25021 ctctctgcag ccgcgatggt tttcccttgc cttttcagtt cttctaccac aatgctggct
    25081 aaactagttt cttccccata accatagcaa aagtctcgta aagaaattcc ttcgaaagtc
    25141 tggcagtcca agatttgatt ttccaagata tccagcgctt gattcgcctc ttcttgactg
    25201 ctagcctttg ttgacagacg tagagtgact tctcctgtct tggcataagg ggccaaggta
    25261 ggatcgatct gattatcaat taaatcagcc aaaatcgtaa ccaactggct ctcgccaatc
    25321 ccaaagaaac gaagaactcg ggaatacagc ttgctccctg tcatcaactt gggtagaagt
    25381 tggtttaaga ccatgggttt caattcactt ggcggacctg gaaggacgac ataggtcact
    25441 ccgtctactt ctaattttcc tccaacagcc agtcctgttt cgtttggcag tggaatcgct
    25501 ccttctacaa tttgagcttg tctttcgtta ttcggtgttc gggcatagtc tggtcgcagg
    25561 gtaaaaaaga tatccaactt ctcctgagcc tgaggatcaa agactaatgc tttccctaaa
    25621 aatttagcta gggtttgttt ggttaggtcg tcctcagttg gccccaaacc gcctgtcaaa
    25681 atcaccagac tgctacgttg actggcaatc tcaagcaaag acaagagacg aacttcattg
    25741 tctcctacag ccgtctgaaa atatacatct accccaatct cagctagttt ttccgacaaa
    25801 aactgggcat tggtgttgac aatctgccct gtcaaaatct ctgttccaac agcaatgatt
    25861 tctgctttca tgtttcctcc tacctatcta ttcgtatttt tttgaaaaaa tcgcaggaat
    25921 tttcctacga ttgatttttt tatttgtatc aaaagttaat tatcttcatc accaacaggt
    25981 gctctgccaa ataaatcttc aaataaaacc gcattggttt caagctgagt aacttcttct
    26041 tgtcccaaag aacgtcggag tagattttgc atttccaaca tatgtgctct cgaaacaatc
    26101 tggtaagaaa caccttgaag tatctctcct tcaccctgca actgctgagt ttcaatggtt
    26161 ttaaatgaat ctttatagcc tagcaagtta gggatacttt ttgcagacaa atcaatattg
    26221 gtctgcatat tgtcactcaa agcttttaga atctcttgat aatgaccaat gctatttaaa
    26281 ctgagagctt tttccatgac tttttgaata acttcacgtt gacgtttttg acgaccataa
    26341 tccccctcag gatcttggta acgcattcgt gcatagacta gggcttcttc tcccccaata
    26401 tgttgctccc caacaccgat agaaatagta ttaaattctt cttggtcact gatagaaatt
    26461 gggaaaccta ggatattatt gactgtaata cctcctactg catccactag tttttgcaat
    26521 cctctcatat tgaccatcac atagcgatca atatggatat tcatcatttt ttgaatggtt
    26581 tctatagcaa gctctgctcc accatctgca tatgctgagt tcagtttcgc ttcatgagcc
    26641 tgaccattcc ctgattcaat gcgcgtcaga atatcccgct ctaaactcat cattgttgtt
    26701 tttttcgttt taggattcac tgtcatcaag atcatgctat cacttctacc gacccaagtt
    26761 tcagttcgtt caacatttcc ggtgtccact cccattaaca gaatggttag aggttcagtc
    26821 gcttcaataa ccttggtttc ttcgccgatt tttttatagg ttttagctaa ggtttctgtc
    26881 ccttgttgat aaatagtata agcaaaaaca cctactccta ctacagttac agaaagtaaa
    26941 gctagcacca ttccaataat ttttttaacc atatttctac taacctatca gtttacccat
    27001 caagtaaaca tcgataaatt tcccttcttc tatatatgcc ccacgctctt ggctaccttc
    27061 aatgacaaag ccatgctttt gataaagatg gactgctgct tgattacgag tttggacagt
    27121 cagttggaga cgacgcagaa tgccacttgc ttgtgcccac tctatcgctt cttctagcaa
    27181 caaacttccc aagccattat tccaatatct ttttccaatc acaatgaaga gatctccaat
    27241 atgacggact ctcttacgct ggtcagctgt aatatttaca ataccagcaa ttttgccatt
    27301 taagaatgca agtaaggtta tctgattgtc cgaactagct tgcttgttga ggaatatttc
    27361 catctcctca ctagtcaaga gaataccatc tccgtctagg ctggtaaagt ctgtctccaa
    27421 actcacacga tttaaaaagg ccactaattc agctgcatct ttgggctctg cttccctaat
    27481 gagcaattca tactccatat tgaagctcct ctaacaattt ctcagcacgc aaaccctttg
    27541 cctgaaaatt taaacggcgt ccatctgctt cttttagaat ttccaattct aaataagcat
    27601 ctggcaaggc atctcctaag agatttcccc actcaataac agtcacgcca ccaccaaaga
    27661 taaactcatc caagtcgata gaatcagcat ctccttcaat acgataaaca tctaggtgat
    27721 aaagtggaag tcgaccttca tactctctca cgatagtata ggtgggactt ttaatcattt
    27781 gagaaatctg taatcctttt gcaagtcctt tagtaaaggt cgttttacct gcacccagtt
    27841 ctccagttaa gattaaaaca tcattctttg ctaatagatg gcccaaactc tcccctaagg
    27901 cttgcaactc ttcttcattt tttgtgtaca tactcttatt ataccaaaaa cttttctttt
    27961 gtgtctattt tcctactaaa cttatcatca taacatccat aaaaaacagg ctttctctaa
    28021 aagaaaatga gcgtaacaat gaccaataca agatctcgga aaatatgacc ataaaaggaa
    28081 acttccttct taaccgaatt tgggacaaga taggctgcaa aaaacaagcc cagtccaata
    28141 taaatcagaa gtgagacaat ggtcattgga tttcttaaga aaagaagtgt tgctaaaata
    28201 gtcaccaaca ctgtcttttt tctgtctagc atagcaagaa aatcgcgcac gtattttttc
    28261 aagggtaaaa aaatcagcaa atctagccca aataggaaaa agaaggatgg caataaaaag
    28321 tcaactaatt cttgctgcag cgtatttttg atgaacaagt tatctgacaa aacaagaaca
    28381 gctcctaaca aattaattaa gagtaacata ctgtaaaaaa gcttcaccga cttcttactg
    28441 gctaggacac tatggacttc ttgcttacgg gtataaagat aatttactcc agcacagatt
    28501 cctgaaacga aaaccatgct tccgatgaaa aaagctgtac tttgtttaaa ggacaagatg
    28561 cattccttcc ataggaaaca gctactcaaa ctgatttgaa ttaaagctaa caaaaataag
    28621 attctcattg atttcatctt ctctctccct tcctaccaat cattatacta ggagaaaaga
    28681 gagaactgtt tctaatcttc tcaaatgtct ctttaagacg ctaaacaaac actagagact
    28741 aatactcaat gaaaatcaaa gatcaaacta ggtagctagc cacaggttgc tcaaaacagt
    28801 gttttgagat tgcagataga gctgacgtga tttgaagaga ttttcgaaga atatagattt
    28861 gaaatcatga aaatccgtca aacgggtggt tgttttgtct cgcacctcac ggagcgagac
    28921 ggactcagag tcacataatt ataaggctga tagtattaat ctaactatca gccttacagg
    28981 ttatttaacg tttcagaaaa actataatgt caagattaac taaacagtat ctagttcctt
    29041 caaataattt tctatcttca tcagcattaa aggattgtta taaatcttgc atagctctct
    29101 tgcttctata taataatttt tgacttgttc tctgtctaga aatttggctc cagcatttcc
    29161 tacaagaata agtagaggag ccaattggta gcttgtctgt ctttgtttac agagttcaat
    29221 cgtttcaaga gcttcttgga tggcttcatt atatttttcc tttgatacta ggtagtgagc
    29281 gtagttgtaa cgaactctga tgtagccaaa taaaaactct tgatggtcca aattttttgt
    29341 ctgatacaac tctattaaat gagagtagtt tgcctcatat tcttgttcac gacccactaa
    29401 ggaatagaaa ttagatagag tattcaacgc ctttaaataa atcagagtat ttgaagagac
    29461 ttttaataat atattttcca atgaagaaat tgcctcacac ttactgtcat attgatagaa
    29521 gtcaataata gctttaatcc attcaaggta agttcggtct tctagtgtta gaaaagtact
    29581 tcgttcaatc tctattctat aaatatattc caaatcgtca taatttctat cgtctaatag
    29641 tcgagcagac aattgcttga aattagagag gttagattta atttcaattt gttcattaaa
    29701 aaaataatct aatggtactt caagtcgttg agagagtttg aacaaaaggt ctgcggaggg
    29761 aatgaaatgc cctctctcaa ttttactaat ctggctttgt tcacaaattc cttctgcaag
    29821 agtttgttgg gagagtctca actcttttct tttcaatctg aatttctctg cgagtgtatt
    29881 cattaaagat aataaacc
//
LOCUS       DBJKQU010000023        28915 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.023, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000023 DBJKQU010000000
VERSION     DBJKQU010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 28915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28915
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.023"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            72..860
                     /gene="codY"
                     /locus_tag="ACSUUC_001146"
     CDS             72..860
                     /gene="codY"
                     /locus_tag="ACSUUC_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HHQ8054365.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            860..1435
                     /locus_tag="ACSUUC_001147"
     CDS             860..1435
                     /locus_tag="ACSUUC_001147"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HHQ8054366.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            1517..1602
                     /locus_tag="ACSUUC_001148"
     tRNA            1517..1602
                     /locus_tag="ACSUUC_001148"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1551..1553,aa:Leu,seq:aag)
     gene            1875..3005
                     /locus_tag="ACSUUC_001149"
     CDS             1875..3005
                     /locus_tag="ACSUUC_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054367.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            3506..4264
                     /locus_tag="ACSUUC_001150"
     CDS             3506..4264
                     /locus_tag="ACSUUC_001150"
                     /EC_number="2.1.-.-"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHQ8054368.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMRLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            4351..4863
                     /locus_tag="ACSUUC_001151"
     CDS             4351..4863
                     /locus_tag="ACSUUC_001151"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HHQ8054369.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            5045..5989
                     /gene="metA"
                     /locus_tag="ACSUUC_001152"
     CDS             5045..5989
                     /gene="metA"
                     /locus_tag="ACSUUC_001152"
                     /EC_number="2.3.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004414 - homoserine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-acetyltransferase MetA"
                     /protein_id="HHQ8054370.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYRYL"
     gene            5998..6675
                     /locus_tag="ACSUUC_001153"
     CDS             5998..6675
                     /locus_tag="ACSUUC_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HHQ8054371.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEISPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            6773..7531
                     /gene="tpiA"
                     /locus_tag="ACSUUC_001154"
     CDS             6773..7531
                     /gene="tpiA"
                     /locus_tag="ACSUUC_001154"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HHQ8054372.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVVSKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            7569..9074
                     /gene="lytC"
                     /locus_tag="ACSUUC_001155"
     CDS             7569..9074
                     /gene="lytC"
                     /locus_tag="ACSUUC_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HHQ8054373.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGTRYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            9570..10088
                     /locus_tag="ACSUUC_001156"
     CDS             9570..10088
                     /locus_tag="ACSUUC_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dps family protein"
                     /protein_id="HHQ8054374.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            10218..10724
                     /locus_tag="ACSUUC_001157"
     CDS             10218..10724
                     /locus_tag="ACSUUC_001157"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HHQ8054375.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            10724..10894
                     /locus_tag="ACSUUC_001158"
     CDS             10724..10894
                     /locus_tag="ACSUUC_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054376.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            10926..12158
                     /gene="clpX"
                     /locus_tag="ACSUUC_001159"
     CDS             10926..12158
                     /gene="clpX"
                     /locus_tag="ACSUUC_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HHQ8054377.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKNENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            12167..12754
                     /gene="yihA"
                     /locus_tag="ACSUUC_001160"
     CDS             12167..12754
                     /gene="yihA"
                     /locus_tag="ACSUUC_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HHQ8054378.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            12765..13145
                     /locus_tag="ACSUUC_001161"
     CDS             12765..13145
                     /locus_tag="ACSUUC_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HHQ8054379.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            13197..14087
                     /gene="rapZ"
                     /locus_tag="ACSUUC_001162"
     CDS             13197..14087
                     /gene="rapZ"
                     /locus_tag="ACSUUC_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HHQ8054380.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            14084..15061
                     /locus_tag="ACSUUC_001163"
     CDS             14084..15061
                     /locus_tag="ACSUUC_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HHQ8054381.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQAILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            15058..15969
                     /gene="whiA"
                     /locus_tag="ACSUUC_001164"
     CDS             15058..15969
                     /gene="whiA"
                     /locus_tag="ACSUUC_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HHQ8054382.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(16003..16968)
                     /locus_tag="ACSUUC_001165"
     CDS             complement(16003..16968)
                     /locus_tag="ACSUUC_001165"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HHQ8054383.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPGQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            17104..17961
                     /gene="cdaA"
                     /locus_tag="ACSUUC_001166"
     CDS             17104..17961
                     /gene="cdaA"
                     /locus_tag="ACSUUC_001166"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HHQ8054384.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            17948..18727
                     /locus_tag="ACSUUC_001167"
     CDS             17948..18727
                     /locus_tag="ACSUUC_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HHQ8054385.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            18751..20103
                     /gene="glmM"
                     /locus_tag="ACSUUC_001168"
     CDS             18751..20103
                     /gene="glmM"
                     /locus_tag="ACSUUC_001168"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HHQ8054386.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KTIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTIEEVDYYVDTITDVVRAEIGID
                     "
     gene            20177..20551
                     /locus_tag="ACSUUC_001169"
     CDS             20177..20551
                     /locus_tag="ACSUUC_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HHQ8054387.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            20553..21401
                     /locus_tag="ACSUUC_001170"
     CDS             20553..21401
                     /locus_tag="ACSUUC_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HHQ8054388.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            21667..22434
                     /gene="dapB"
                     /locus_tag="ACSUUC_001171"
     CDS             21667..22434
                     /gene="dapB"
                     /locus_tag="ACSUUC_001171"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HHQ8054389.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLPDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            22431..23630
                     /locus_tag="ACSUUC_001172"
     CDS             22431..23630
                     /locus_tag="ACSUUC_001172"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HHQ8054390.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAI
                     TEKYQSLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            23627..25498
                     /locus_tag="ACSUUC_001173"
     CDS             23627..25498
                     /locus_tag="ACSUUC_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HHQ8054391.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMSRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQVKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(25641..26825)
                     /gene="mntE"
                     /locus_tag="ACSUUC_001174"
     CDS             complement(25641..26825)
                     /gene="mntE"
                     /locus_tag="ACSUUC_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HHQ8054392.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            27129..>28915
                     /locus_tag="ACSUUC_001175"
     CDS             27129..>28915
                     /locus_tag="ACSUUC_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HHQ8054393.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVILANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEDHVLTGAELNELSDEDFEKVVG"
BASE COUNT         8537 a         5322 c         6683 g         8373 t
ORIGIN      
        1 aattttcaga taattattga aaaagagacg tttttatgtt ataatgatag cgattaaatt
       61 cgaggtgaaa aatggcacat ttattagaaa aaactagaaa aattacatca attttgaaac
      121 gctcagagga gcagttgcag gatgagctcc cttacaacgc tattacgcgt cagttagcgg
      181 atattattca ttgcaatgcc tgcattatca atagtaaggg acgtctgctt ggctatttta
      241 tgcgttataa aacaaataca gatcgcgtag agcaattctt ccaaactaag attttcccag
      301 atgactacgt tcaaggggct aatatgattt acgaaacaga agcaaacttg cctgttgagc
      361 atgatatgag tattttccct gttgagagta gagatgattt tccagatggc ttgacgacta
      421 ttgcaccgat tcatgtatcg gggattcgcc ttggttcttt gattatttgg cgtaatgata
      481 aaaaattcga agatgaggac ttggttcttg ttgagattgc cagtaccgtt gttgggattc
      541 agcttcttaa cttccaacgt gaagaagatg agaaaaatat tcgtcgtcgt actgctgtca
      601 ccatggcggt caataccctt tcttactccg aactccgtgc tgtttcagca attttagggg
      661 aattaaatgg aaatgaaggg aagttgactg cgtcagtgat tgcagatcgt atcggaatca
      721 ctcgctctgt gattgtcaat gctcttcgta aacttgagtc tgcggggatt attgaaagtc
      781 gctcacttgg aatgaaggga acctatctta aggtcttgat ttcagatatt tttgaagaag
      841 tgaagaaaag agattactaa tgacaaaggc tttaatttcg attgattata cagaagattt
      901 tgttgctgat agtgggaagc tgacagcagg tgctccagct caggcgattt cggatgccat
      961 cagcaaggta actcgattag cttttgaacg aggagattat atcttcttta ctattgatgc
     1021 tcatgaagaa aacgattttt tccatccgga aagtaagtta tttcctcctc ataatctgat
     1081 tgggacgagt ggacggaatt tatatggaga tttggggatc ttttatcaag agcatggttc
     1141 agacagtcgt gtcttttgga tggataaacg ccattactca gctttttcag ggactgacct
     1201 agatattcgt ttgagagagc gtagagtgtc taccgttatc ttaacaggtg tcttgacgga
     1261 tatctgtgtc ctacatacag ctatagatgc ctataatcta ggatatgaca tcgagattgt
     1321 taaaccagct gttgcttcca tctggcctga aaatcatcaa tttgccctag gtcatttcaa
     1381 aaatacactc ggagctaagt tagtagatga aaatctaaat gaactttctg agtaacctgg
     1441 ttggtgaaaa tgaaaaaatt tgaaaaaaag tgttgacaag catcccaaaa gttgatatac
     1501 tagtaaagta atcgatgcgg ggatggcgga attggcagac gcgcaggact aaggatcctg
     1561 tgaccgcttt aggtcgtgag ggttcaagtc cctctctccg cataggaaaa gagttagcta
     1621 aagctagctc ttttgtattt ctctaaaaaa ttagaatcca gtcaaatgta gtggagaatc
     1681 agcgaaaata tgggaaaact gatccttgtt tctgcttttg tcatagaaga ataataaatt
     1741 caaattctcc gatattctct aaagttttgt gcaagttgca cagaactttt ttattttttt
     1801 ggtcatcttg ccatagaaat ataaagcgtt ttcatctata atataattat caaaagacaa
     1861 aaggagttca cctcatggta gaattgaatc ttaaaaatat ttacaaaaaa tatccaaaca
     1921 gcgaacacta ttcagttgaa gatttcaact tgaacatcaa agataaagaa tttatcgttt
     1981 tcgtaggacc ttcaggatgt ggtaaatcaa ctacactccg tatgattgct ggtcttgaag
     2041 acattacaga aggtactgca tctatcgatg gcgtggttgt caacgacgta gctccaaaag
     2101 accgtgatat cgccatggta ttccaaaact acgctcttta cccacacatg actgtttatg
     2161 acaacatggc tttcggtttg aaattgcgta aatacagcaa agaagacatt aacaaacgtg
     2221 ttcaagaagc agctgaaata cttggattga aagaattctt ggaacgtaaa ccagctgacc
     2281 tttcaggtgg tcaacgtcaa cgtgttgcca tggggcgtgc gattgtccgt gatgcgaaag
     2341 tattcttgat ggacgaacct ttgtcaaact tggatgccaa acttcgtgta tcaatgcgtg
     2401 ctgaaatcgc taaaattcac cgtcgtatcg gagctacaac tatctatgta actcacgacc
     2461 aaacagaagc gatgacactt gcagaccgta tcgttattat gtcagctact aagaaccctg
     2521 ctggtacagg tactatcgga cgtgtagaac aaatcggtac tcctcaagaa gtttacaaaa
     2581 atccagttaa caaatttgtt gcaggattca tcggaagccc agctatgaat ttcatcaacg
     2641 tgaaattggt tggtagcgaa attgtttctg acggtttccg tttgaaagtg ccagaaggag
     2701 cattgaaagt tcttcgtgaa aaaggctacg aaggaaaaga attgatcttt ggtatccgtc
     2761 cagaagacgt gaatgcagaa cctgctttcc ttgaaacatt cccagactgt gttgtaaaag
     2821 cgactatctc tgtatcagaa ctgcttggtt cagaatctca cctttactgc caagttggta
     2881 aagacgagtt tgttgcaaaa gttgatgctc gtgactactt gcaaacaggt gcaacagttg
     2941 agcttggatt tgacttgaac aaagcacact tcttcgatgt agaaactgaa aaaacaatct
     3001 actaaaataa ataaaattca aagcactaca agaaaagata tctctttatc aattgtagtg
     3061 gagagatatc agttaatcta gggagagaaa caaaatgctt ctctcctttt tgctagggaa
     3121 gtcatattat gcatctatat tgtgatgctc tttaatactc ttcgaaaatc tcttcaaacc
     3181 acgtcaacgt cgccttgccg tacgtatgat tactgatttc gtcagtttta tctgcaacct
     3241 caaagatgta ctttgagcag cttacggcta gtttcctagt ttgctctttg atttccattg
     3301 agtattattt gtgggtacca tctacaagtg aagctatatg cgtaaactac gtgagcaatt
     3361 gaattcgaac tagagaggta ataataaatt tatgctatag ttatggtgac ttgtatgctt
     3421 ttgattctag tttatcaaat aatagattag aattgtcaga taatatcatt ttgtgttata
     3481 atgaagaaaa aacagaggtg ttcaaatgtc agaagcaggt cataagtttt tagcaaaatt
     3541 ggggaaaaaa cgcttacgtc caggtggaaa gcgtgccaca gattggttaa ttgcagaagg
     3601 aggattttca aaagaaaaga gaatactaga ggttgcgtgt aataggggaa ctacagcaat
     3661 tgagttggca cagcgttttg gttgtaagat aactgctgtt gatatggatg ctcaagcttt
     3721 agaagtggct aaaaaatctg ctggaacggc aggtgttgct catttaatca gttttgaaag
     3781 agcaaatgca atgaaacttc cttatcaaga tgctagtttt gatattgtta taaatgaagc
     3841 tatgctgact atgcaagccg atcaagctaa gaaaaaatgt gtaatggaat atctaagggt
     3901 attaaaacct ggaggtcttc tattgacgca tgatgtgctt cttaaggaag ctaaagagtc
     3961 tatcagacag gaattatcac aagcaattca tgtaaatgta ggtcctttaa ctcaagatgg
     4021 ttgggaacag gtgatgatag aatcaggtta ttgtgatgtg aaagtattga ctggtgaaat
     4081 gacattaatg agattatcgg gtatgattta tgacgaaggt ttgctaggaa ctttgaaaat
     4141 ttgtgtaaat gcttgtaaaa aggagaatag aaagcagttt ttaactatgt ataaaatgtt
     4201 tgctaagaat aaacagaaat tgggctttat tgcgatggct agttataaat cgtcaaaacg
     4261 ttagataatt attgaagtta acttttcctt ttttctttct taaaaaatat gctataatag
     4321 agagtaaaaa actttgaaag aaagaaaaag atgaatttaa aagattacat tgcaacaatt
     4381 gaaaattatc caaaggaagg cattaccttc cgtgatatta gtcctttgat ggctgatgga
     4441 aatgcttata gctacgctgt tcgtgaaatc gttcagtatg ctactgacaa gaaagtcgac
     4501 atgatcgtgg gacctgaagc tcgtggattt atcgtgggtt gtccagttgc ctttgagttg
     4561 ggaattggtt ttgcgcctgt tcgtaagcca ggtaaattgc cacgcgaagt tatttctgct
     4621 gactatgaaa aagagtacgg tgtcgatacc ttgactatgc acgcggatgc cattaagcca
     4681 ggtcaacgtg ttcttattgt agatgacctt ttggcgacag gtggaactgt taaggcaact
     4741 atcgagatga ttgaaaaact tggtggtgtt atggcaggtt gtgccttcct tgttgaattg
     4801 gatgaattga acggccgtga aaaaattggt gactacgact acaaagttct tatgcattat
     4861 taatgaaaac agtccctagg gctgttttct ctacactagg atataaaaat agactataac
     4921 tagttagaga aaaactataa ttgaaaacta tatcttcttg cagtataata aaaggactaa
     4981 gtgtttgaga tttgtcttca aacatatgca attattcctg aaagagtaca gttaggagag
     5041 ggttatgccg attcgaattg ataaaaaatt gccagctgtt gagattttac ggacagagaa
     5101 tatctttgtc atggatgatc aacgtgctgc ccaccaagat atccgtcctt tgaagatttt
     5161 aattttaaat ctcatgccac agaaaatggt cacagagacc cagttgttgc gccacttggc
     5221 taatacaccc ctacaactgg atattgattt tctctatatg gagagccacc gttctaaaac
     5281 aactcgttca gagcacatgg agaccttcta taaaactttt cctgaagtca aggatgagta
     5341 ttttgatggg atgatcatca cgggtgctcc agttgagcat ttaccatttg aggaagtgga
     5401 ctattgggag gaatttagac agatgcttga gtggtctaag actcatgtct attcgaccct
     5461 tcatatctgt tggggggctc aggctgggct ttatctgcgc tatggtgtag aaaaatacca
     5521 gatggacagt aagctatcag gtatttatcc tcaggacacc ctaaaagagg gtcaccttct
     5581 atttagaggc tttgatgata gctatgtatc ccctcattca cggcacacgg agatttctaa
     5641 ggaagaggtc ttaaacaaga ccaatctcga gattttatca gaaggacctc aggttggggt
     5701 ttctattttg gccagtcgtg atttacgaga aatttatagt tttggtcatt tggagtatga
     5761 ccgtgatacc ttggcaaaag agtattttcg agatcgtgat gcaggtttcg acccacatat
     5821 tccagaaaat tactttaaag atgatgatgt taatcaggta ccttgtcttt gttggtcttc
     5881 atctgcagcc ctctttttca gtaattgggt aaaccatgcg gtctatcagg agacgccttt
     5941 tgactggaga aagatagaag atgatgcatc tgcatatagg tatttataag aggaattatg
     6001 acatatttag acgcttttaa atcaggtacc ttggttttac cgagtgccct gctcttgcat
     6061 tttaaggaac tctttccttc tagcgacgat tttctggttt ggcaattttt ctatttgcaa
     6121 aatacgacag gcttagaaga aatatcgcca agccagattg ctgaaaggat tggcaaggaa
     6181 atttcggatg tcaaccagtc catttctaat ctgacggaaa ggggactgct ccagtatcgt
     6241 actatcgaat taaatggcga aattgaattg ctctttgatg ctagtttggc cttggaacgt
     6301 ttggatgacc tgtttggagc agttcattca agttcagacc agctaacacc acaaaaccag
     6361 ctcaaggatt tggtggaaac cttccagcag gagttgggac gattgttgac gccttttgag
     6421 attgaggatt tgaccaagac actaaaggaa gatggaacca gtgctgactt gattaaggag
     6481 gctcttcgtg aagctgtttt gaacggaaaa ccaaactgga agtacattca ggcgattttg
     6541 agaaactggc gccatgaagg aatcaagagt gtggctcaaa ttgaggccaa gagagcagaa
     6601 agagaagcaa gcaatcctca gttgacacag gtatctgcag atttcataaa tgccatggat
     6661 ctctggaagg attaatccat gcaagtaggc ttgaaatccg agtaagattt gcaagctgtg
     6721 tataattgtg atagaataaa tagaaaataa attgaaaaaa gaggtatgtg aaatgtcacg
     6781 taaaccattt atcgctggta actggaaaat gaacaaaaat ccagaagaag ctaaagcatt
     6841 cgttgaagca gttgtatcaa aacttccttc atcagatctt gttgaagcag gtatcgctgc
     6901 tccagctctt gatttgacaa ctgttcttgc tgttgcaaaa ggctcaaacc ttaaagttgc
     6961 tgctcaaaac tgctactttg aaaatgcagg tgctttcact ggtgaaacta gcccacaagt
     7021 tttgaaagaa atcggtactg actacgttgt tatcggtcac tcagaacgcc gtgactactt
     7081 ccatgaaact gacgaagata tcaacaaaaa agcaaaagca atctttgcga acggtatgct
     7141 tccaatcatc tgttgtggtg aatcacttga aacttacgaa gctggtaaag ctgctgaatt
     7201 cgtaggtgct caagtatctg ctgcattggc tggattgact gctgaacaag ttgctgcctc
     7261 agttatcgct tatgagccaa tctgggctat cggtactggt aaatcagctt cacaagacga
     7321 tgcacaaaaa atgtgtaaag ttgttcgtga cgttgtagct gctgactttg gtcaagaagt
     7381 cgcagacaaa gttcgtgttc aatacggtgg ttctgttaaa cctgaaaatg ttgcttcata
     7441 catggcttgc ccagacgttg acggtgccct tgtaggtggt gcgtcacttg aagctgaaag
     7501 cttcttggct ttgcttgact ttgtaaaata atcagtaagt agcaaaagct aggtggaaca
     7561 gcattcagat gtctgttaca ttttttatag gagaggaaag attgaaaata aaaattggat
     7621 tagcaagtat ctgtttacta ggcttggcaa ctagtcatgt cgctgcaaat gaaactgaag
     7681 tagcaaaaac ttcgcaggat acaacgacag cttcaagtag ttcagagcaa aatcagtctt
     7741 ctaataaaac gcaaacgagc gcagaagtac agactaatgc tgctgcccac tgggatgggg
     7801 attattatgt aaaggatgat ggttctaaag ctcaaagtga atggattttt gacaactact
     7861 ataaggcttg gttttatatt aattcagatg gtcgttactc gcagaatgaa tggcatggaa
     7921 attactacct gaaatcaggt ggatatatgg cccaaaacga gtggatctat gacagtaatt
     7981 acaagagttg gttttatctc aagtcagatg gggcttatgc tcatcaagaa tggcaattga
     8041 ttggaaataa gtggtactac ttcaagaagt ggggttacat ggctaaaagc caatggcaag
     8101 gaagttattt cttgaatggt caaggagcta tgatgcaaaa tgaatggctc tatgatccag
     8161 cctattctgc ttatttttat ctaaaatccg atggaactta tgctaaccaa gagtggcaaa
     8221 aagtgggcgg caaatggtac tatttcaaga agtggggcta tatggctcgg aatgagtggc
     8281 aaggcaacta ctatttgact ggaagtggtg ccatggcgac tgacgaagtg attatggatg
     8341 gtactcgcta tatctttgcg gcctctggtg agctcaaaga aaagaaagat ttgaatgtcg
     8401 gctgggttca cagagatggt aagcgctatt tctttaataa tagagaagaa caagtgggaa
     8461 ccgaacatgc taagaaagtc attgatatta gtgagcacaa tggtcgtatc aatgattgga
     8521 aaaaggttat tgatgagaac gaggtggatg gtgtcattgt tcgtctaggt tatagcggta
     8581 aagaagacaa ggaattggcg cataacatta aggagttaaa ccgtctggga attccttatg
     8641 gtgtctatct ctatacctat gctgaaaatg agaccgatgc tgagaatgac gctaaacaga
     8701 ccattgaact tataaagaaa tacaatatga acctgtctta ccctatctat tatgatgttg
     8761 agaactggga atatgtaaat aagagcaaga gagctccaag tgatacagac acttgggtta
     8821 aaatcatcaa caagtacatg gacacgatga agcaggcggg ttatcaaaat gtgtatgtct
     8881 atagctatcg tagtttatta cagacgcgtt taaaacaccc agatatttta aaacatgtaa
     8941 actgggtagc ggcctatacg aatgctttag aatgggaaaa cccttattat tcaggagaaa
     9001 aaggttggca atatacctct tctgaataca tgaaaggaat ccaagggcgc gtagatgtca
     9061 gcgtttggta ttaagcgatg atttgaaaga gggatgtgat agtagcaccc tctttttctt
     9121 tgttttatga tagttcatcc tcgagtaaat tcaagatctt gctcggaaat gaagcttata
     9181 tagtagattg aatatagaca aataccttgt gattggtaaa acattttaga aattcattta
     9241 cctttcctaa tcgacttggt ttcatcttat ttcaatctat tatagtattg gggaatttct
     9301 tcaaaccaca tcagcttggt cagttctacc tgcgacctca aaacttgtgc tttggtcaag
     9361 ctgggtttag tttcctagtt tgctgatgga tttccattga ctataagcat ccaaccctct
     9421 ttttgtcttc taaagaattc ttaaattatc agtctattgc aacttttctc atataagttc
     9481 tttgtcttgc tattggtttt ccttagtagt atactaaggt agtaatcatt aagaagtggt
     9541 tacaaaaaat aatgaatgag gtaaagaaaa tggtagaatt gaaaaaagaa gcagtaaaag
     9601 acgtaacatc attgacaaaa gcagcgccag tagcattggc aaaaacaaag gaagtcttga
     9661 accaagctgt tgctgatttg tatgtagctc acgttgcttt gcaccaagtg cactggtata
     9721 tgcatggtcg tggtttcctt gtatggcatc caaaaatgga tgagtacatg gaagctcttg
     9781 acggtcaatt ggatgaaatc agcgaacgct tgattacact cggtggaagc ccattctcta
     9841 cattgacaga gttccttcaa aatagtgaaa tcgaagaaga agctggtgaa taccgtaatg
     9901 ttgaagaaag cttggaacgt gttcttgtta tctaccgtta cttgtcagaa cttttccaaa
     9961 aaggtttgga tgtcactgat gaagaaggtg acgatgtgac aaacggtatc tttgcaggcg
    10021 ctaaaactga aacagataaa acaatttgga tgcttgcagc cgaacttgga caagcacctg
    10081 gtttgtaaga aataaggaaa catagataaa tctgtaggaa atttcttaca gattttttct
    10141 attttgtaag ctattccaaa ccagtctttt tttgagtttt ttgataaaat agtactatca
    10201 gtgaaaagga tggaagcatg actaagaaaa tcgtagctat ttgggcccag gatgaagagg
    10261 gtgtgattgg taaggacaat cgtctgcctt ggcatttgcc agcagaattg cagcacttta
    10321 aagaaacaac tctgaatcat gctatcttga tggggcgtgt gacctttgat gggatggggc
    10381 gtcgcttgct tccaaaacgg gaaaccctga ttttgacgcg taatccggaa gaaaagatag
    10441 atggggttgc tacttttcag gacgtccagt ctgttcttga ctggtatcag gctcaagaaa
    10501 agaatctcta cattatcggt gggaagcaaa tttttcaggc ttttgaacct taccttgatg
    10561 aagtgattgt cactcacatt catgctcggg tggaaggaga tacctatttc cctgaagaac
    10621 ttgacttgtc tctttttgag acagtttcaa gcaaatttta cgccaaagat gagaagaatc
    10681 cttatgattt taccatccaa taccgcaaga gaaaggaagt ctaatggaac ggagtttatt
    10741 tggtctattc acggcttttc tgtgtttcat ctgctttctg gcaggagcac aggcttttcg
    10801 taaaaagcgt tacgggcttt ctatcctcct ttggttaaat gcctttacca atctggtcaa
    10861 tagtattcat gctttttaca tgaccttatt ttagatagaa tgacagtata gaatggaagg
    10921 aaatcatgtc tacaaataga aaaaatgata tgatggttta ttgctcattt tgtggcaaaa
    10981 accaagaaga agtacaaaaa ataattgctg gcaacaatgc ttttatttgt aatgaatgcg
    11041 tggagttagc tcaggaaatc attcgagaag aattggttga ggaagtcttg gcagacttgt
    11101 ctgaggtgcc aaaaccaatt gaactcctcc atatcttgaa ccactatgta attggtcaag
    11161 atcgtgccaa gcgtgccttg gcagtggcgg tttataacca ctacaaacgc atcaatttcc
    11221 acgatacacg cgaagagtca gaagatgtgg atttgcagaa gtcaaacatt ttgatgattg
    11281 gcccaactgg ttcagggaaa actttccttg cccagacctt ggctaagagc ttgaatgtac
    11341 cttttgctat tgcggatgcg acagctctga cggaggctgg ttatgtgggt gaggatgtgg
    11401 aaaatatact cctcaaactc ttgcaggttg ctgactttaa catcgaacgt gcagagcgtg
    11461 gcattatcta tgtggatgaa attgacaaga ttgccaagaa gaatgagaat gtgtctatca
    11521 cacgtgatgt ttctggtgaa ggggtgcaac aagcccttct caagattatc gagggaactg
    11581 ttgctagcgt accgcctcaa ggtggacgca aacatccaca acaagagatg attcaagtgg
    11641 atacaaaaaa tatcctcttc atcgtgggtg gtgcttttga tggtattgaa gaaattgtca
    11701 aacaacgtct gggtgaaaaa gtcatcggat ttggtcaaaa caataaggcg attgacgaaa
    11761 acagctcata catgcaagaa atcatcgctg aagacattca aaaatttggt attatccctg
    11821 agttgattgg acgcttgcct gtttttgcgg ctcttgagca attgaccgtt gatgacttgg
    11881 ttcgcatctt gaaagagcca agaaatgcct tggtgaaaca ataccaaacc ttgctttctt
    11941 atgatgatgt tgagttggaa tttgacgacg aagcccttca agagattgct aataaagcaa
    12001 tcgaacggaa gacaggggcg cgtggacttc gctccatcat cgaagaaacc atgctagatg
    12061 ttatgtttga ggtgccgagt caggaaaatg tgaaattggt tcgcatcact aaagaaactg
    12121 tcgatggaac ggataaaccg atcctagaaa cagcctagag gtgactatgg aacttaatac
    12181 acacaatgct gaaatcttgc tcagtgcagc taataagtcc cactatccgc aggatgaact
    12241 gccagagatt gccctagcag ggcgttcaaa tgttggtaaa tccagcttta tcaacactat
    12301 gttgaaccgt aagaatctcg ctcgtacatc aggaaaacct ggtaaaaccc agctcctgaa
    12361 cttttttaac attgatgaca agatgcgctt tgtggatgtg cctggttatg gctatgctcg
    12421 tgtttctaaa aaggaacgtg aaaagtgggg gtgcatgatt gaggagtact taacgactcg
    12481 ggaaaatctc cgtgcggttg tcagtctagt tgaccttcgt catgacccgt cagcagatga
    12541 tgtgcagatg tacgaatttc tcaagtatta tgagattcca gtcatcattg tggcgaccaa
    12601 ggcggacaag attcctcgtg gtaaatggaa caagcatgaa tcagcaatca aaaagaaatt
    12661 aaactttgac ccaagtgacg atttcatcct cttttcatct gtcagcaagg cagggatgga
    12721 tgaggcttgg gatgcaatct tagaaaaatt gtgaggaaaa gaaaatggca aaaacaattc
    12781 atacagataa ggccccaaag gctatcgggc cctatgttca aggaaaaatc gttggcaacc
    12841 ttttgtttgc tagcggtcaa gttcccctat cccctgaaac tggggaaatt gtaggagaga
    12901 atatccaaga acagacagag caagtcttga aaaacatcgg tgctattttg gcagaagcag
    12961 gaacagactt tgaccatgtt gtcaaaacaa cttgtttctt gagcgatatg aacgactttg
    13021 ttccttttaa tgaggtttac caaacggcct tcaaagagga attcccagct cgttcagctg
    13081 tggaggtagc tcgtcttcct cgtgatgtaa aagtcgaaat tgaagtcatc gcagagattg
    13141 gataagctag ttgaagtttg gtgttgccaa acttcttttg atataaggag aaaaagatga
    13201 caaagaaaca acttcacttg gtgattgtga cagggatgag tggcgcaggg aaaactgtag
    13261 ccattcagtc cttcgaggat ctaggttatt tcaccattga taatatgccg ccagctctct
    13321 tgcctaagtt tttgcagctg gttgaaatta aggaagacaa tcctaagttg gccttggtag
    13381 tggatatgcg tagccgttct ttcttttcag agattcaagc tgttttggat gagttggaaa
    13441 atcaagatgg tttggatttc aaaatcctct ttttggatgc ggctgataag gaattggtcg
    13501 ctcgttacaa ggaaaccaga cggagtcacc cactagcagc agacggtcgt attttagatg
    13561 gaatcaagtt ggaacgtgaa ctcttggcac ctttgaaaaa tatgagccaa aatgtggtgg
    13621 atacgactga actcactcca cgtgagctgc gcaaaaccct tgcagagcag ttttcagacc
    13681 aagaacaagc ccagtctttc cgtatcgaag tcatgtcttt cggatttaag tatggaatcc
    13741 cgattgatgc ggacttggtc tttgatgtcc gtttcttgcc aaatccctat tatttaccag
    13801 aactgagaaa ccaaacgggt gtggatgaac ctgtttatga ttatgtcatg aaccatcctg
    13861 agtcagaaga cttttatcaa catttattgg ccttgattga gccgattctg ccaagttacc
    13921 aaaaggaagg taagtccgtt ttgaccattg ccatgggatg tacgggtgga caacaccgta
    13981 gtgtggcatt tgctaaacgc ttggtgcagg acttatccaa gaattggtct gttaatgaag
    14041 ggcatcgcga caaagaccgc agaaaggaaa cggtaaaccg ttcatgagaa aaccaaagat
    14101 aacggtgatt ggtggaggga ctggaattcc cgtcattcta aaaagtctgc gggaaaaaga
    14161 tgtggaaatc gcagctatcg tgacggtggc agatgatggt ggttcttcag gtgaactccg
    14221 aaaaaatatg caacagttga caccgccagg tgatcttcgt aatgtccttg tggccatgtc
    14281 ggatatgcct aagttttatg agaaggtctt tcagtatcgg ttctctgagg atgccggagc
    14341 ctttgctggc catccattgg gaaatctcat cattgctggc ttgtcagaaa tgcagggttc
    14401 aacctataat gccatgcagt tattgagcaa atttttccat acaacaggga aaatttatcc
    14461 ttccagtgac catcctttga cccttcatgc agtctttcag gatgggacag aagtggctgg
    14521 agagagtcat attgtagacc atcgaggcat aattgacaat gtctatgtga ccaatgccct
    14581 aaacgatgat acgcctctgg ccagccgtcg agtagtgcag gccatccttg aaagtgacat
    14641 gattgtccta gggccaggtt ccctctttac ctctattttg cccaatatcg tgattaagga
    14701 aattgggcgg gctcttttgg aaactaaggc agaaattgcc tatgtctgta atatcatgac
    14761 ccaacgtggg gagacggaac actttacaga tagcgaccac gtggaagtct tgcatcgtca
    14821 ccttggtcgc ccttttatcg acactgtctt ggtgaatatt gaaaaagtgc ctcaggaata
    14881 catgaattcc aaccgttttg atgaatactt agtgcaagtg gaacacgatt ttgtaggtct
    14941 ttgtaagcaa gtttcgcgcg tgatttcatc taacttcctt cgtctggaaa atggcggtgc
    15001 cttccacgat ggagatttga ttgtggacga gttgatgcgc attatacagg tgaaaaaatg
    15061 agtttcacag tagcagtaaa agaagaaatc ctgggccaac accatctgag ctggcatgaa
    15121 ttatctgcca ttatcaaaat gtctggtagc atcggtctct cgacttcggg cttgactttg
    15181 tcagttgtga cagaaaatgc caaactggcc cgtcacctct atgagtcctt tcttcatttc
    15241 tatgaaatca aatctgaaat tcgtcaccac caacgtagca atcttcgcaa gaatcgcgtc
    15301 tataccgttt ttacagatga aaaggtgcag gatttgttaa gtgatttgca cttggcagac
    15361 tctttctttg gcctggaaac aggtattgat gaggcgattt tatcggatga ggaagcaggt
    15421 cgtgcctatc tctgtggcgc tttcttggca aatgggagca ttcgtgaccc tgagtcaggc
    15481 aagtaccagt tggaaatcag ttctgtttat ctggaccacg cgcaaggaat tgcctccctt
    15541 ctccaacagt ttttactgga tgccaaggtg cttgagcgca agaagggggc tgtgacctat
    15601 ctccagcgag cagaagacat tatggacttc ttgatagtaa tcggagccat gcaggcacgt
    15661 gatgattttg agcgggttaa gattttgcga gaaacccgta acgacctcaa tcgggctaat
    15721 aatgccgaga cagctaatat cgctcggaca gtttctgcca gcatgaagac cattaacaat
    15781 atcagtaaaa tcaaagatat catgggctta gaaaatttgc cagtagattt gcaggaagtg
    15841 gcgcaactga ggattcagca cccagactac tctatccagc agttagcaga tagtctcagc
    15901 acccctctga ccaaaagtgg tgtcaatcac agactcagaa aaatcaataa gatagccgat
    15961 gaattataaa accacgaatc ctatgtgact cgtggttctt ttttataaac tggtagagtg
    16021 ttttggttgt actttttgtt cagggtcaat gtagttgata gcgttgttga cagcagttgg
    16081 agcttctccg aggcctgtcg caatcagatc aatttttccg tcatagtagc agcagtcacc
    16141 gatagcatag atacctgctt ggctggattc ttgtttgctg ttgacgataa tcttgtgacg
    16201 gttgaggtcg agcccccagt ttttaaggtt accgacagaa gatttgaaac catagttgac
    16261 aaagaggtgg tctaggtcaa tggtttcagt ttcatcagat ttgacttttg tgatttcaag
    16321 tttatcaagt gtttttccat ttccaaggag ttggccaggg gcgaatggtg tcttgatggt
    16381 tacagatgat tcttgcaagg cttgaacact gtgttccaag gcacggaaat tatctctgcg
    16441 gtgaacaagg gtagttggtg cgattttttc aaaagccaaa gcccaatcca cagccgagtc
    16501 tcccccacca agaatcgtca ctttcttacc agcgtattgc tgaatgttag aaacgtggta
    16561 gtggatattt tcatagccct caaccccttc aagttccagc ggacgtggtt tgaaggcacc
    16621 gccacccata gcgatgataa ctgttttagt caggtgactt cctttagaag ttgtgatggc
    16681 aaattcttct tgtttgtcaa tctcaagaac cgtttcattg agatgaatag gggtatcaaa
    16741 tccatttagc tgttcaatca agcggttagt caactcttct ccagtcaggt ttgggaagcc
    16801 tggtacgtct aggatttcct tttcagggta gagaatagca ggttgtccac ctagctgggg
    16861 aagagagtcg atgatttgaa ccttggcttg gcgtaggtgg gcataaaagg ctgcaaaaag
    16921 cccgacagga ccaccaccca caatggtaat atcatagagt tgagacatag tttctccttt
    16981 gttttttcta gtcagtttat tttatcatat ttttgttcaa tgtaaaatgg actaggatag
    17041 ggaaaaaaat gcccgaaaat ggtataatag gacgaaagtg ttttgatagg gaggatatca
    17101 gggatgaatt ttcaacaatt atccaatctg caatattgga ccagtttgtt tgcaagtcca
    17161 tggacgatag ctatcaatct gattgatatt ttgattgttg cttatatttt ataccatttt
    17221 acaaaagcta ttgcaggaac caagattatg attttggtac gtggagtttt ggtatttatt
    17281 ttagctcaaa tccttgcaaa tatgattggt ttgactacga tttcttggtt aatcaatcaa
    17341 attattactt atggggttat tgcggcggtt gttatcttct ctccagagat tcggactggt
    17401 ttggaacgtt tgggaagagc gacagatttc ttttccaatg cccctattag tgctgaggaa
    17461 cagatgattc gtgcctttgt taagtctgtt gaatacatga gtcctcgtaa aatcggggcc
    17521 ttggttgcta ttcagcgtgt acgtaccttg caggagtata tttcgacagg aattcccttg
    17581 gatgctaaga tttctgcaga acttctcatt aacattttta ttcccaacac tcccctacat
    17641 gacggtgcgg tgattatcaa agaagaacgt atcgctgtga cgtctgccta tctgcccttg
    17701 acaaaaaaca cagggatttc caaggaattt gggaccagac accgggcggc tatcggttta
    17761 tcagaagtct cagatgcctt gacttttgtc gtatcagagg aaacgggagg aatttcgata
    17821 acctataatg gaaggtttaa gcacaaccta acacttgatg aatttgaaac agaattacgt
    17881 gaaatcttac ttccaaaaga ggaagtgggt cttagtttta aagaacgatt gctaggagga
    17941 tggaaacatg aaaaaaaata gtttatatat catatcctca ctcttttttg cttgtgtctt
    18001 atttgtctat gctacggcga cgaattttca aaacagtacc agtgctaggc aggtaaaaac
    18061 ggaaacctat actaatacag taacaaatgt ccctattgac atacgctata atagtgataa
    18121 gtattttatt agcggttttg cttcagaagt atcagtggtc ttgactggtg caaatcgcct
    18181 atcgctagct agtgaaatgc aagaaagtac acgtaaattc aaggttactg ctgacctaac
    18241 agatgccggt gttggaacga ttgaagttcc tttgagcatt gaagatttac ccaatgggct
    18301 gaccgctgtg gcgactccgc aaaaaattac agtcaagatt ggtaagaagg ctcagaagga
    18361 taaggtaaag attgtaccag agattgaccc tagtcaaatt gatagtcggg tgcaaattga
    18421 aaatgtcatg gtgtcagata aagaagtgtc gattacgagt gaccaagaga cattggatag
    18481 aattgataag attatcgctg tcttgccaac tagcgaacgt ataacaggta attacagtgg
    18541 ttcagtacct ttgcaggcaa tcgaccgcaa tggtgttgtc ttaccggcag ttatcactcc
    18601 gtttgataca ataatgaagg tgactacaaa accagtagca ccaagttcaa gcacatcaaa
    18661 ttcaagtaca agcagttcat cggagacatc ttcgtcaacg aaagcaacta gttcaaaaac
    18721 gaattaaaaa tagaaaagga ttttataaca atgggtaaat attttgggac tgatggagtc
    18781 cgtggagaag ctaacctaga actaacacca gaattagcct ttaaactagg acgttttgga
    18841 ggctatgttc ttagtcaaca tgaaacggaa gcgccgaaag tctttgtagg acgtgacaca
    18901 cgtatttcag gggaaatgct ggaatcggcc ttggtggcag gtctcctttc agtagggatt
    18961 cacgtataca aacttggtgt ccttgcaaca ccagcagtag cttacttggt tgaaactgaa
    19021 ggagcaagtg ccggtgtcat gatttctgct agccacaacc cagcccttga taacggaatc
    19081 aagttctttg gcggtgatgg cttcaaacta gatgatgaaa aagaagcaga aattgaagcc
    19141 ttgctagatg ctgaggaaga cactcttcct cgtccaagtg cagaaggctt aggaattttg
    19201 gtagattatc cagaaggctt gcgtaagtat gaaggatacc ttgtttcaac tggaactcct
    19261 cttgatggaa tgaaggttgc cttggataca gctaatggag cagcttctac cagtgcccgt
    19321 caaatctttg cagaccttgg tgcccaattg acggttatcg gggaaacacc agacggtctt
    19381 aacatcaacc ttaatgttgg ttcaacacat ccagaagccc ttcaagaagt ggtcaaagaa
    19441 agtgggtcag ctattggttt ggcctttgat ggagacagtg accgcttgat tgctgttgat
    19501 gagaatggtg acatcgtcga tggtgacaag attatgtata tcatcggaaa atacctttct
    19561 gaaaaaggac aattggctca aaatacaatt gtgacaactg ttatgtctaa ccttggtttc
    19621 cacaaggcct tgaatcgcga aggtattaac aaggcagtta ctgcagttgg tgaccgctac
    19681 gttgttgaag aaatgagaaa atcaggctac aaccttggtg gtgaacagtc tggtcacgtt
    19741 atcttgatgg attacaatac cacaggtgat ggtcaattat cagcagttca attgactaaa
    19801 atcatgaagg aaactggtaa gagcttatca gagttggcgg cagaagtaac gatttatcca
    19861 caaaaattag ttaatatccg agtggaaaac gtcatgaagg aaaaggccat ggaagtgcca
    19921 gctatcaaga ccatcatcga gaagatggaa gaagaaatgg cggggaacgg ccgtatcctt
    19981 gttcgtccaa gtggaacaga gcccctcttg cgtgttatgg cagaagcgcc tacaatagaa
    20041 gaagtggact actatgttga taccatcaca gatgtagttc gtgctgaaat tgggattgac
    20101 taaatcctag aaaactagat gaaaataaaa aattatggta caatagctta taatattgta
    20161 gccgatggag aaagacatga atcttaaacg tgaacaagaa tttgttagtc agtatcattt
    20221 tgatgcgcgt aattttgaat gggaaaatga aaatggagct cctgaaacca aggtggatgt
    20281 gaatttccaa ttgctccaac atgaccaaga aaatcaagtg acttccttga ttgtcatctt
    20341 gagctttatg attgtatttg ataagtttgt cattagtgga acaatctcac aagtaaacca
    20401 tatcgatggc cgtattgtca atgaaccaag tgaattgaac caagaagagg tggaaacctt
    20461 ggctcgtcca tgtttgaaca tgctcaatcg tttgacttac gaagtgactg aaattgcatt
    20521 agacttacca ggaattaatt tggagttcta atatgaaatt agctgttttc acagattcct
    20581 ctgcttatct cagtgaagag accttgcaaa gagaagactt gtttgtcttg gatattcctg
    20641 tcaatattga tggtgaggaa tatgtcgaag gcatcaatct gtctgctgag gaattttacc
    20701 aaaaaatggc tcaggcttct gaattgccta agaccagtca accaagtatt gccaagttag
    20761 atgagatctt aacttcgctc aaagaacaag gctatacaca tgccttgggg cttttcctat
    20821 cttctggaat ttcaggtttt taccaaaata tccagtatat ggtcgatgac tatgagggct
    20881 taaccattgc tttcccagac actttgatta caagtgctcc cctaggcatc atggttgaaa
    20941 gcgtctttaa ttggcgtgat cagggcgatg attttgccag cattcaggat aagctagcca
    21001 ttcaaatcag ccgtacgtca gcctttatca tggtagatga cttggatcat ttggtaaaag
    21061 gtggacgcct ttcaaatggg gctgccattt tgggcaattt gcttagcatt aagccaatcc
    21121 tttattttaa cgatcaaggt gtgattgaag tttacgaaaa agttcgtact gaaaagaagg
    21181 ccaccaaacg cttaattgaa attatcaagg aaacaacggc ttcaggtcaa taccgggtca
    21241 ttgtcattca tgggaatgct cctgaaaagg ctgaagaatt gcgtcagcat ttgcttgatt
    21301 ttggcttggg ttcggatgtt tcacttgcta catttggtag tgtcattgga acgcacctag
    21361 gagcaggaag tattgctctg ggttatattc cagtgattta gtaggcactt ctaggctagt
    21421 taatcttagc aattgaacac ggactacctg cctcttgaaa aaagatgtct gtcttgcctt
    21481 tcgtggaaag tcagtgccat tccctatttt tcatgggtgg ctaagatcct ttgtattttg
    21541 ataattgaac acgcctggaa ccctgtgtga aaaagatagt tcttccaagg agtagacact
    21601 tcttgatcag aattcctatt ttcactttgt gttcttacag gctttgtatc ttagacagga
    21661 gtagagatga gtattcgagt aattattgcc ggttttaagg gaaagatggg tcaagctgct
    21721 tgccagatgg tcttgcctga ttcagatttg gacttggtag cagttttgga tccttttgag
    21781 tctgagtcag aatggcaggg tattcctgtt ttcaaggata aggctgattt agctggtttt
    21841 gaagcggatg tctgggtaga ctttactact ccagctgttg cctacgaaaa tacacgtttt
    21901 gctcttgaaa atggctttgc tccagtagtt ggaacgactg gtttcacgag tgaagaaatt
    21961 gcagagctaa aagaattttc tcgtgcccaa gacttgggtg gcctgattgc ccctaacttt
    22021 gccttgggtg ctgtcttact catgcaattt gcgacgcagg ctgccaaata tttcccaaat
    22081 gtggagatta ttgagctcca tcatgacaag aaaaaggatg ctccgagtgg aacagccatt
    22141 aaaacagctg agttgatggc agaggttcga gagtcaattc agcaaggtgc agcagatgag
    22201 gaagagctga ttgctggtgc tcgtggtgct gactttgatg gtatgcgcat ccactcagtt
    22261 cgtttgccag gcttggtagc tcatcaggaa gtcatctttg gcaatcaggg agaagggttg
    22321 accctccgtc atgactccta tgatcgcatc tccttcatga caggagtcaa tttgggaatt
    22381 aaagaagttg tcaagcgtca tgagcttgtc tatggattag aacacttatt atgagattaa
    22441 cgcaaatgcc ttctgaattt cagaaggctt taccagtatt agaaaaaatt aaagaagcag
    22501 gctttgaggc ttattttgtt gggggctctg ttcgagatgc ccttctccat agccctatcc
    22561 acgatgtgga tattgcgacg tcttcttatc cagaagagac caagcagatt tttccgcgaa
    22621 cagccgatat cggaatcgag catggaaccg tcttggtctt agatggggat gaggagtatg
    22681 aggtaacaac ctttcggaca gaggatgtct atgtggacta tcgcagaccc agtgcggttt
    22741 cctttgtgcg ctcgctagaa gaagacctca aacgccgtga tttcacagtc aacgcctttg
    22801 ccttggatga gacaggagaa atcgttgact tgttccatgg tttagaagat ttggaaaagc
    22861 aagtcttgcg agcagttgga gtggctagtg agcgtttcaa cgaagatgct ttacggatta
    22921 tgcgtggttt ccgttttcag gctagtcttg gttttgcact tgagccagaa acatttaaag
    22981 ctatgaagac cttgacgccg cttttggaga aaatttctgt agagcgtacc ttcgtcgaat
    23041 ttgataaact cttgctggct ccattttgga gaaggggctt ggcttccatg attgagagtc
    23101 aagcttatga ctatctccct gatatggcat ctagccagga caagctcaac agactgtttg
    23161 atttggagac tgattttact tttgaatcct ctgaacaagc ctgggcggct ttactatggg
    23221 ctttggagat tgaaaatgcg cagtcatttt tgaaatcttg gaagacctca cgccagtttg
    23281 ccaagcaagt tcaggatttg ctgattattt tggctctgcg tgaaaatgga gaattgagca
    23341 agcgagattg ttatcgcttt gacatagatt tgcttttaca ggctgaaaat cttcgtcaag
    23401 ctcaaggaaa agaagtcaac ccacaagcca tcacagaaaa ataccaaagc ttgactatcc
    23461 atgacaagaa agagattcag attaatggcg atattttgat caaggaatat ggctatcagc
    23521 caggcccaga cttgggagag attttaacag agattgagtt tgccattgtc gatggagaat
    23581 tggagaataa tcgtgaagcc atccatgctt acctgaggga gaaaaaatga gtgattttat
    23641 cgttgaaaaa ctaagtaaat ccgttggtga caagaccgtt tttagggata tttcctttat
    23701 tatccatgac ttagacagaa ttggtttaat cggtgtcaat gggactggca agaccaccct
    23761 tttggacgtc ctttctggtg tttctggatt tgatggggat gtcagtcctt tttcagctaa
    23821 aaatgattac cagattggtt atttgactca ggatcctgat tttgatgata gaaagacagt
    23881 tttggatacg gttctatcta gtgaactcaa ggaaatccag ctcattcgtg agtatgaatt
    23941 gattatgctc gactatagtg aggacaagca ggcgcgtttg gaacgtgtca tggcagagat
    24001 ggactctctc caagcttggg aaatcgagag tcaggtcaag accgttctta gcaaattggg
    24061 cattcaagac ttatctactc ctgttgggga attgtcaggt ggtctgagaa gacgggtaca
    24121 gttggcacaa gtcttacttg gcaaccacga ccttttgctt ttggatgagc cgaccaacca
    24181 tctggatatt gcgattattg agtggctgac cctctttttg aaaaattcta agaagaccgt
    24241 cctttttatc actcacgatc gttatttctt agacgctttg tcaacacgga ttttcgagtt
    24301 ggagcgagca ggcttgacag aatatcaggg caattaccag gactatgttc gccttaaggc
    24361 agaacaggac gagcgcgatg cagctctact tcataaaaaa gaacaactct acaaacaaga
    24421 actggcctgg atgagcagac aaccgcaggc gcgtgcgacc aagcaacaag ctcgtatcaa
    24481 tcgtttccat gatctgaaaa aggaagtttc aggcagtagt gctgagacag acttgactat
    24541 gaactttgaa accagtcgga ttgggaagaa agtcatcgag tttcaggctg tttcctttgc
    24601 ctatgaaaat aagcccattt tgcaagattt taatctctta gttcaggtta aagaccgtat
    24661 tggaattgtt ggggacaatg gtgttggaaa atcaacccta cttaacctga ttgcaggaag
    24721 tcttgagccg acagcaggac aagttgtgat tggggaaact gttcgcatcg cctatttctc
    24781 tcaacaaatt gagggtttgg atgaaagcaa gcgtgtgatc aattacctgc aggaagtggc
    24841 agaggaggtc aagaccagtg gtggttctac gacttccatc gctgagttgc tggagcaatt
    24901 cctcttccca cgttcgacgc atgggacctt gattgagaag ttgtcagggg gtgagaaaaa
    24961 acgtctttat ctcctcaaac tgcttttgga aaaaccaaat gttcttcttt tagacgagcc
    25021 aaccaatgac ctagatattg caactttgac agtcttagag aatttcttgc aaggttttgc
    25081 aggtcccgtt ttaacagtca gtcacgaccg ctatttcttg gataaggtag cgaccaagat
    25141 tctcgctttt gaggatggca agattcgtcc tttctttggt cattacaccg actatcttga
    25201 tgaaaaagct tttgaaacag atatggccaa tcaagtgcaa aaggccgaaa aggaaaaagt
    25261 ggtcaaggtt cgagaagaca agaaacgcat gacctaccaa gaaaagcagg agtgggcaag
    25321 tattgaaggt gatattgaaa ccttggaaaa acgtatcgct gctattgaag aggaaatgca
    25381 ggctaacggc tctgactttg gtaagctggc tactctccaa aaagaattgg atgagaaaaa
    25441 tgaagcactc cttgaaaaat acgaacgcta tgagtatctc agtgaatttg atagttaaga
    25501 ctattcgaaa atcaaagtgc aaactatgtc ggcttcacat tgccgactca agtacagcct
    25561 gtgaccggct tcctaatttg cactttgatt tttattgagt ataaaagaat agaaaaatcc
    25621 cgtctcatga aaggatttct ctattctttt ttggtttctt gatgaaagat attttgccag
    25681 gtttcgtggc gacgccagat actggtatgg atgataccat ctaactcata gcagatgagt
    25741 ttggtttttt gactgatgga agtaatttga atgtccttga tagcagaatt taactctttt
    25801 ttggtcttat aagcctcttt atccatctgc tctccatctt ggcgaatata gacaaaatca
    25861 tcagtcaaga gttcttctag ttggtttcct tggtcaatca attgttcacg cataagcaat
    25921 tttttataga cattgtctaa aatttcatcc tcagggatag gtgctggttc gatatggaca
    25981 tcggtatcaa agacgccaaa acgctcctcc agcatagact cgacctgatc cgcgatttca
    26041 tggctttcaa aaacagacaa gtcaggattc atctctagtg taatatccag gtagatgttg
    26101 ctaccgtagg tgcgacctct ttgcgatttg accttgctga ttttgggaat ttccatgata
    26161 gccttttggt agtcctcgag caggcggtcg tcaaagccat ctgaaagact aaaggaagac
    26221 tcgatgaaga tatcataggc agtcttcaag ataaagaaag tgatgatgat agcaaccagt
    26281 ttatccacaa tcggataatt gaaactacta gctaggatgg caatggcggt tccaagtgag
    26341 gtaacagcgt cagaaagatt gtccttagca gctgccttca gcgccttgga gttggatttc
    26401 ttactgaggc gagtattgta gagatagacc acaaacataa tcgctgcaga aatgattcct
    26461 agagttgcac caagaggatc aatgaccgtt tcttcccgac tgagaatctt ttgaatggta
    26521 tctcttagaa catcgaaacc gacatagaac atgatgatag aagtgatcaa gcttgccaaa
    26581 tcttcaatct tccaatgacc aaaacggtgg tcacggtctg caggctggcg cgccatccga
    26641 atcccgatta agagggccac atttccaatg atgtccgata cgttattaaa accatcggcc
    26701 accaaactgg atgaatgaag gagatgacca gctgctaatt tggctgcaga caagatcaaa
    26761 taggtcgaaa tactgataat ggctccacgc tcagctaact tgagatttga gatagattgc
    26821 ttcattcaac ttcctttcta gtcacatagc attctaccat tatactggtt ttcaaggaaa
    26881 aattcaaata aggcagtttt tactctttga aaactcccca aaatttggta taatggtact
    26941 actcaaggga gtagctggca gaaacctgtg atagtgtcgt cattccgaat tttatgctga
    27001 aaagtatgct ttccggccct atcttaaaca gcgagacttg ttatgattaa caggtctctt
    27061 tttgtttgtc gtgaaaagat atgacagaaa gagagtctgt tttgcacaca atgtcaagga
    27121 ggagacacat gtcaaaagaa caaaaacgcc aagcgtttta tactcagagc cctgaagagg
    27181 tcttgcaggc tgtggatgcg accgagcaag gtttgtcatc aagtgaggcg gaaaagcgcc
    27241 ttgccgaatt tgggcacaat gaactcgaag aaggcgagaa acgatcaatc ttggtcaaat
    27301 tcatcgagca atttaaggat ttgatgatta tcatcctagt tgcggcagca atcttgtcag
    27361 tcgtgacttc tggtggggaa gatatcgcag atgccattat catcctagct gtggttatca
    27421 tcaacgctgc ctttggtgtt taccaagaag gaaaagctga agaagctatt gaagccctca
    27481 aatccatgtc tagtccagtt gcccgcgttc ttcgtgatgg acacatggca gagattgact
    27541 ctaaagaatt ggtaccaggc gatatcgttg cccttgaagc aggtgacgtg gtaccagcgg
    27601 acctacgttt gatagaagcc aactctctta aaattgaaga agcagccttg acaggtgaat
    27661 ctgtaccagt cgaaaaagac ttgtcagtcg agcttgcgac agatgctggt attggtgacc
    27721 gtgtcaacat ggccttccaa aactcaaacg taacctatgg tcgtgggatg ggtgttgttg
    27781 tcaatacagg tatgtacact gaagttggtc atattgctgg tatgcttcaa gatgcggatg
    27841 agactgatac accactcaaa caaaatttga acaacctttc taaggtcttg acctatgcta
    27901 tcttggtcat tgcccttgtt acttttgtag tgggtgtctt cattcaaggg aaaaatccac
    27961 ttggtgagtt gttgacttct gttgcccttg ccgttgcagc cattccagaa ggacttcctg
    28021 ctatcgttac catcgttctt tctcttggta ctcaagtttt ggccaaacga cattccatcg
    28081 ttcgtaagtt gccagcagtt gaaacacttg gttcaactga aatcatcgct tctgataaga
    28141 ctggtacgct gactatgaac aagatgacag tcgaaaaagt cttctacgat gcggttctac
    28201 atgactcagc tgatgatatt gaactaggtc ttgaaatgcc actacttcgt tcagttatct
    28261 tggccaatga tacgaaaatc gatgtggaag gtaacttgat tggtgaccca accgaaacag
    28321 cctttatcca atatgccttg gacaagggct atgatgtcaa aggtttctta gagaaatatc
    28381 ctcgtgtagc tgaattgcca tttgactctg accgtaagct catgtcaaca gttcacccat
    28441 tgccagatgg tcgtttcctt gtagcagtca agggtgcgcc agaccaactc ttaaaacgtt
    28501 gtcttcttcg tgataaggct ggggatattg ctccgattga tgagaaggtt acaaatctca
    28561 ttcatacaaa caattctgaa atggctcatc aagccttgcg tgtccttgca ggtgcttata
    28621 agattatcga tagtattcca gaaaatctca cttctgaaga gcttgaaaat gatttaattt
    28681 ttactggttt gattgggatg attgatcctg aacgtcctga agctgctgag gctgttcgtg
    28741 tggctaagga agctggaatt cgtccaatta tgattacagg tgaccaccaa gacaccgcag
    28801 aagctattgc caaacgtttg ggaatcattg acgcaaacga tacagaagac cacgttttaa
    28861 ctggtgctga gctcaacgaa ttatctgatg aagactttga aaaagttgtt ggtca
//
LOCUS       DBJKQU010000024        27641 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.024, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000024 DBJKQU010000000
VERSION     DBJKQU010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.024"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(203..490)
                     /locus_tag="ACSUUC_001176"
                     /pseudo
     CDS             complement(203..490)
                     /locus_tag="ACSUUC_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            489..752
                     /locus_tag="ACSUUC_001177"
                     /pseudo
     CDS             489..752
                     /locus_tag="ACSUUC_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            799..1497
                     /locus_tag="ACSUUC_001178"
     CDS             799..1497
                     /locus_tag="ACSUUC_001178"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047465 - N-acylglucosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HHQ8054394.1"
                     /translation="MSQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            1516..3033
                     /locus_tag="ACSUUC_001179"
     CDS             1516..3033
                     /locus_tag="ACSUUC_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHQ8054395.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTSGRGEEVDSKEISESADSTSNIADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            3158..4486
                     /locus_tag="ACSUUC_001180"
     CDS             3158..4486
                     /locus_tag="ACSUUC_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHQ8054396.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            4738..5604
                     /locus_tag="ACSUUC_001181"
     CDS             4738..5604
                     /locus_tag="ACSUUC_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHQ8054397.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            5620..6459
                     /locus_tag="ACSUUC_001182"
     CDS             5620..6459
                     /locus_tag="ACSUUC_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHQ8054398.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            6732..7184
                     /locus_tag="ACSUUC_001183"
     CDS             6732..7184
                     /locus_tag="ACSUUC_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HHQ8054399.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            7281..7625
                     /locus_tag="ACSUUC_001184"
     CDS             7281..7625
                     /locus_tag="ACSUUC_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054400.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVRLLTKIFGWILRIAVLAADVYGNFANNIAAAWDA
                     HDKIPNNGRINF"
     gene            7635..7829
                     /locus_tag="ACSUUC_001185"
     CDS             7635..7829
                     /locus_tag="ACSUUC_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054401.1"
                     /translation="MKALCIFLLYMLAWTVLAMIIRGGLDGFDEHTWRNILASALSSL
                     YIHYISIDRKRKKSKRKKKK"
     gene            7912..8556
                     /locus_tag="ACSUUC_001186"
     CDS             7912..8556
                     /locus_tag="ACSUUC_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HHQ8054402.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            8725..9642
                     /locus_tag="ACSUUC_001187"
     CDS             8725..9642
                     /locus_tag="ACSUUC_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HHQ8054403.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKDKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            9660..10544
                     /locus_tag="ACSUUC_001188"
     CDS             9660..10544
                     /locus_tag="ACSUUC_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HHQ8054404.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(10560..11411)
                     /locus_tag="ACSUUC_001189"
     CDS             complement(10560..11411)
                     /locus_tag="ACSUUC_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHQ8054405.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDGNCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            11611..13668
                     /gene="pbp2b"
                     /locus_tag="ACSUUC_001190"
     CDS             11611..13668
                     /gene="pbp2b"
                     /locus_tag="ACSUUC_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HHQ8054406.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            13679..14275
                     /gene="recR"
                     /locus_tag="ACSUUC_001191"
     CDS             13679..14275
                     /gene="recR"
                     /locus_tag="ACSUUC_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HHQ8054407.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            14451..15494
                     /locus_tag="ACSUUC_001192"
     CDS             14451..15494
                     /locus_tag="ACSUUC_001192"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HHQ8054408.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            15578..16951
                     /locus_tag="ACSUUC_001193"
     CDS             15578..16951
                     /locus_tag="ACSUUC_001193"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HHQ8054409.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAYLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGNQSVQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            16938..17549
                     /locus_tag="ACSUUC_001194"
     CDS             16938..17549
                     /locus_tag="ACSUUC_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HHQ8054410.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEGSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDINRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPVLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            17640..18344
                     /locus_tag="ACSUUC_001195"
     CDS             17640..18344
                     /locus_tag="ACSUUC_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HHQ8054411.1"
                     /translation="MNLWDIFFTTQATKPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIVKEA"
     gene            18563..19936
                     /gene="ftsA"
                     /locus_tag="ACSUUC_001196"
     CDS             18563..19936
                     /gene="ftsA"
                     /locus_tag="ACSUUC_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HHQ8054412.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            19953..21212
                     /gene="ftsZ"
                     /locus_tag="ACSUUC_001197"
     CDS             19953..21212
                     /gene="ftsZ"
                     /locus_tag="ACSUUC_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HHQ8054413.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            21217..21888
                     /locus_tag="ACSUUC_001198"
     CDS             21217..21888
                     /locus_tag="ACSUUC_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HHQ8054414.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYIGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            21898..22437
                     /locus_tag="ACSUUC_001199"
     CDS             21898..22437
                     /locus_tag="ACSUUC_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA];
                     GO_process: GO:0090529 - cell septum assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HHQ8054415.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            22437..22700
                     /locus_tag="ACSUUC_001200"
     CDS             22437..22700
                     /locus_tag="ACSUUC_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HHQ8054416.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            22697..23482
                     /locus_tag="ACSUUC_001201"
     CDS             22697..23482
                     /locus_tag="ACSUUC_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HHQ8054417.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            23491..24279
                     /gene="divIVA"
                     /locus_tag="ACSUUC_001202"
     CDS             23491..24279
                     /gene="divIVA"
                     /locus_tag="ACSUUC_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HHQ8054418.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMAELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            24627..27419
                     /gene="ileS"
                     /locus_tag="ACSUUC_001203"
     CDS             24627..27419
                     /gene="ileS"
                     /locus_tag="ACSUUC_001203"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HHQ8054419.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEYGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT         8363 a         5056 c         6073 g         8149 t
ORIGIN      
        1 aataaaacat tgaggaaata ataaaaatct atgggtaatg ttctgaaagt acttttaggt
       61 taggagagaa atataatgat ttttgaaaat tgattcaaaa aatagcgaat tgtagaaaac
      121 gcttaacaaa tggtgtataa tagacttcca gcgaaacaaa atatgctaca ataaacctat
      181 gaattataaa gcaaccttat actcatctgt cttcacaaag cattctagtc catctccgat
      241 taacgatgga ctttatcatc tccttctcca gtccttgtat gacatcttcc aaagttcgaa
      301 aggctttatt cttaaatcca cgtttacgaa tctctttcca cacttattca atggggttca
      361 tttctggtgt gtatggagga ataaatgcaa agccaatatt agtcggaatc tttaaggcac
      421 ttgatttatg ccatatagca ttgtccataa cgaataaaag ataatcatct ggataagctt
      481 gtgaaagctt ggctgacagt ggttatcaag ggctcatgaa gatatatctt caagcacaaa
      541 ctccacgtaa atccagcaaa ctcaagccgc taacagctga agataaagcc tataaccatg
      601 cgctatctaa ggagagaagc aaggttgaga atatttttgc caaagtaaaa acgtttaaaa
      661 tgttttcaac aacctatcga aatcatcgta aacgcttcgg attacgaatg aatttgattg
      721 ctgatattat caatcatgaa ctaggattct agttttgcag gaagtctaat aaatgtataa
      781 gaaaaaggag gaaaaaggat gtcacagatt agcaaagaag ccttgattga gcaaatcaaa
      841 gatggaatca tcgtttcttg tcaggctctt cctcatgaac cgctttatac agaagcggga
      901 ggggtgattc ccttgctggt caaagcggct gagcaaggtg gagcagtcgg tatccgagca
      961 aacagtgttc gcgatatcaa ggaaattaag gaagtcacta aacttccaat cattgggatt
     1021 atcaaacgtg attatccacc tcaggaaccc ttcatcacgg ctactatgaa agaagttgat
     1081 gaattggcag aactggacat cgaggtgatt gctctggatt gtaccaagcg tgaacgctac
     1141 gatggtttgg aaattcaaga gttcattcgt caggttaagg agaaatatcc taatcagctt
     1201 ttgatggctg atactagtat cttcgaagaa gggctagcag ctgtagaagc aggaattgac
     1261 tttgtcggaa caaccttatc aggctacaca tcctacagtc caaaagtaga cggtccagat
     1321 tttgaattga ttaagaaact ctgtgatgcc ggtgtagatg tcattgcaga aggaaaaatt
     1381 catacaccag aacaagccaa acaaatcctt gaatatggag tgcgaggcat cgttgttggt
     1441 ggcgccatta ctagaccaaa agagattaca gaacgcttcg ttgctagtct taaataagat
     1501 gtgaggggga gttttatgtt taaagtttta caaaaagttg gaaaagcttt tatgttacct
     1561 atagctatac ttcctgcagc aggtctactt ttggggattg gtggtgcact ttcaaaccca
     1621 accacgatag caacttatcc aatactagac aatagtattt ttcaatcaat attccaagta
     1681 atgagctctg caggagaggt tgtattcagt aatttgtcac tacttctctg tgtgggatta
     1741 tgtattggct tagcgaaacg agataaagga accgctgcgt tagcaggagt aactggttac
     1801 ttagttatga ctgcaacgat caaagcttta gtaaaacttt ttatggcaga aggatctgca
     1861 attgatactg gagttattgg agcattagtt gtcggaatag ttgccgtata tttgcacaac
     1921 cgatataaca atattcaatt accttccgct ttaggattct ttggaggttc acgcttcgtt
     1981 cctattgtta catcgttctc ttctatcttg attggctttg tcttctttgt tatttggcca
     2041 cctttccaac aacttcttgt ttctacaggt ggatatattt ctcaggcggg tccaattgga
     2101 acttttctat atggattttt aatgagactt tctggagcag taggcttaca tcatataatt
     2161 taccctatgt tttggtatac tgaacttggt ggtgttgaaa ctgttgcagg acaaacagtg
     2221 gttggagctc aaaaaatatt ttttgctcaa ttagccgatt tggcccattc tggattattt
     2281 acagaaggaa caaggttttt tgcaggtcgt ttctcaacaa tgatgttcgg tttaccggct
     2341 gcctgtttag cgatgtacca tagtgttcct aaaaatcgtc gtaaaaaata cgcgggtttg
     2401 ttttttggag ttgctttaac atcttttatt accggtatta cagaaccaat tgaatttatg
     2461 tttctattcg tcagtccggt tctatatgtt gttcacgcat tccttgatgg tgttagcttc
     2521 tttattgcag acgtcttaaa tatttcaata ggaaacacat tttcaggagg tgtaatcgat
     2581 ttcactttat ttggaatttt gcaggggaac gctaagacga attgggttct tcagattcca
     2641 tttggactta tttggagtgt tttgtattat attattttta gatggttcat tactcaattc
     2701 aacgttctaa cgtcaggacg aggagaagaa gtagattcta aagaaatttc tgaatccgca
     2761 gattcaactt caaatattgc agattattta aaacaggata gcctacaaat tatcagagcc
     2821 ttgggtggat caaataatat agaagatgta gatgcttgtg tgacacgttt acgtgtagct
     2881 gtaaaagaag ttaatcaagt tgataaagca cttttaaaac aaattggtgc agttgatgtc
     2941 ttagaagtga agggtggcat tcaagcaatc tatggagcaa aagcaatctt atataaaaat
     3001 agtattaatg aaattttagg tgtagatgat taagtactta ctgacttaat aaaaaacaga
     3061 ggagagtgat ggatgagtag gatgaaatga aatcgcatac aagaaataaa gaactcatta
     3121 tccaagttgg atacgcttat tacataggag aatacaaatg aaatttagaa aattagcttg
     3181 tacagtactt gcgggtgctg cggttcttgg tcttgctgct tgtggcaatt ctggcggaag
     3241 taaagatgct gccaaatcag gtggtgacgg tgccaaaaca gaaatcactt ggtgggcatt
     3301 cccagtattt acccaagaaa aaactggtga cggtgttgga acttatgaaa aatcaatcat
     3361 cgaagcgttt gaaaaagcaa acccagatat aaaagtgaaa ttggaaacca tcgacttcaa
     3421 gtcaggtcct gaaaaaatca caacagccat cgaagcagga acagctccag acgtactctt
     3481 tgatgcacca ggacgtatca tccaatacgg taaaaacggt aaattggctg agttgaacga
     3541 cctcttcaca gatgaatttg ttaaagatgt caacaatgaa aacatcgtac aagcaagtaa
     3601 agctggagac aaggcttata tgtatccgat tagttctgcc ccattctaca tggcaatgaa
     3661 caagaaaatg ttagaagatg ctggagtagc aaaccttgta aaagaaggtt ggacaactga
     3721 tgattttgaa aaagtattga aagcacttaa agacaagggt tacacaccag gttcattgtt
     3781 cagttctggt caagggggag accaaggaac acgtgccttt atctctaacc tttatagcgg
     3841 ttctgtaaca gatgaaaaag ttagcaaata tacaactgat gatcctaaat tcgtcaaagg
     3901 tcttgaaaaa gcaactagct ggattaaaga caatttgatc aataatggtt cacaatttga
     3961 cggtggggca gatatccaaa actttgccaa cggtcaaaca tcttacacaa tcctttgggc
     4021 accagctcaa aatggtatcc aagctaaact tttagaagca agtaaggtag aagtggtaga
     4081 agtaccattc ccatcagacg aaggtaagcc agctcttgag taccttgtaa acgggtttgc
     4141 agtattcaac aataaagacg acaagaaagt cgctgcatct aagaaattca tccagtttat
     4201 cgcagatgac aaagagtggg gacctaaaga cgtagttcgt acaggtgctt tcccagtccg
     4261 tacttcattt ggaaaacttt atgaagacaa acgcatggaa acaatcagcg gctggactca
     4321 atactactca ccatactaca acactattga tggatttgct gaaatgagaa cactttggtt
     4381 cccaatgttg caatctgtat caaatggtga cgaaaaacca gcagatgctt tgaaagcctt
     4441 cactgaaaaa gcgaacgaaa caatcaaaaa agctatgaaa caatagtcct tagttattct
     4501 ataaaaagta gttttttaaa gaacctaaga gtgtataccc ccttttccct ctacacagat
     4561 agtgtaagaa aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa
     4621 gttcttacat aagcgaacca taaaaaattt cattttgatt ttaaaacagt tcaagaaagt
     4681 caaaaaatta ttctatttga aagagaggtg ccgactgtga aagtcaataa aatccgtatg
     4741 cgggaaacag tgatttccta cgctttccta gcaccagtat tattcttctt tgtcatcttt
     4801 gtgttggctc cgatggtgat gggcttcatt acaagtttct ttaactactc aatgactaaa
     4861 tttgagtttg tgggcttaga taactatatc cgtatgttta aagatcctgt ctttacaaaa
     4921 tctctgatta acacagttat tttggttatt ggatctgtac cagttgttgt tctattctca
     4981 ctctttgtag catctcagac ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc
     5041 gtcttcttcc ttcctgttgt aacgggtagt gttgccgtga cagttgtttg gaaatggatt
     5101 tatgacccgc tatcagggat tctaaacttt gtccttaagt caagccacat catcagccaa
     5161 aacatttctt ggttgggaga taaaaactgg gcattgatgg cgattatgat tattctcttg
     5221 accacttcag ttggtcagcc catcatcctt tatatcgctg ccatggggaa tattgacaat
     5281 tcactggttg aagcggcgcg tgttgatggc gcaactgagt ttcaagtttt ttggaagatt
     5341 aaatggccaa gccttcttcc aacaactctt tatattgcaa tcatcacaac aattaactca
     5401 ttccagtgtt tcgccttgat tcagcttttg acatctggtg gtccaaacta ctcaacaagt
     5461 accttgatgt actaccttta cgaaaaagcc ttccaattga cagaatacgg ctatgccaac
     5521 acaattggtg tcttcttggc agtcatgatt gctatcgtaa gctttgttca atttaaagta
     5581 cttggaaacg acgtagaata ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa
     5641 ccattaacag cctttactgt tatttcaaca atcattttgc tcttgttgac tgtgctgttc
     5701 atctttccat tctactggat tttgacaggg gcattcaaat cacaacctga tacaattgtt
     5761 attcctcctc agtggttccc taaaatgcca accatggaaa acttccaaca actcatggtg
     5821 cagaaccctg ccttgcaatg gatgtggaac tcagtattta tctcattggt aaccatgttc
     5881 ttagtttgtg caacctcatc tctagcaggt tatgtattgg ctaaaaaacg tttctatggt
     5941 caacgcattc tatttgctat ctttatcgct gctatggcgc ttccaaaaca agttgtcctt
     6001 gtaccattgg tacgtatcgt caacttcatg ggaatccacg atactctctg ggcagttatc
     6061 ttgcctttga ttggatggcc attcggtgtc ttcctcatga aacaatttag tgaaaatatt
     6121 cctacagagt tgcttgaatc agctaaaatc gacggttgtg gtgagattcg taccttctgg
     6181 agtgtagcct tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt taccttcatc
     6241 aatacttgga atgactactt catgcaattg gtaatgttga cttcacgtaa caatttgacc
     6301 atctcacttg gggttgcgac catgcaggct gaaatggcaa ccaactatgg tttgattatg
     6361 gcaggagctg cccttgctgc tgttccaatc gtcacagtct tccttgtctt ccaaaaatcc
     6421 ttcacacagg gtattactat gggagcggtc aaaggataat actctgcgaa aatcgaatgc
     6481 aaactacgtc agcttcacct tgccatactt aagtattgcc tgcggttagc ttcctagttt
     6541 gttcttcaat tttcattgag tataggaaaa tcaatctatc aagatacaga agtatatttt
     6601 atagatttag agaatataga ggttataagt gtctacaaaa tggagggtat gcagttactt
     6661 tatgaagttt tgtcagacac ttatcaactt aagaatggtt ttagttaact atcagaaacg
     6721 aaggaaagag tatgattttt gacgatttga aaaacatcac cttttacaaa gggattcatc
     6781 ccaatttaga caaggctatc gactacctct accaacatcg taaagattca ttcgaattag
     6841 gaaagtatga gattgatgga gataaagtct ttctagttgt tcaggaaaat gtcctcaatc
     6901 aagttgagaa taatcaattt gaacaccata agaactatgc agatttgcat ttgctgatag
     6961 aagggcatga atattcgagc tacggttcac gtatcaaaga cgaggcagta gcattcgacg
     7021 aagcgagtga cattggcttt gttcattgtc atgaacacta cccgctcttg ttgggttatc
     7081 acaattttgc gattttcttc ccaggtgagc cacatcagcc aaatggttat gcaggcatgg
     7141 aagaaaaggt tcgaaaatat ctctttaaaa tcttgattga ttaaaaatag gatgaattgt
     7201 ttttttgtaa agctttgata atactctacc atgaaattga tctttgtgag gtagagaaat
     7261 gagaataaaa tatttaaaaa ttggtatctt ctaagtatgc tgcaagagct agtttcttag
     7321 atggacaggg gattacagtt gatgagatgt cctggataat taggggcatt gtgaatggat
     7381 tgattggtag atacataaaa ttaggtactt atgcagctaa gtatggtatt agtatggcgc
     7441 gctcgatctt aagtagggca gctgcaactg cggcagcaag agtaagatta ttgactaaga
     7501 tttttggatg gattttacga atagctgtgc tcgcagctga tgtatatggt aattttgcca
     7561 acaatattgc tgcagcttgg gatgcacatg ataaaatccc taacaatggt cgtataaact
     7621 tttaaaatgc gagaatgaaa gcactttgta tttttttatt gtatatgtta gcttggacag
     7681 tgcttgcaat gataatccgt ggagggctag atggatttga tgaacacact tggcgtaata
     7741 ttttagctag tgcgttgtcc tcgctataca tacattatat atccatagat agaaaaagaa
     7801 aaaagtccaa aagaaaaaag aaaaaataga tttgttcatg gtagggactt atgaaagctt
     7861 tactaacaaa aaagaaaaca gtttacaaag aaaaatgatg gaggagcaaa catggcacaa
     7921 aaaggagtaa gccttatcaa ggcagcattt gatacagata actttctcat gcgttttagt
     7981 gagaaagtct tggacatcgt gacagccaat cttctttttg tcgtctcttg tttgcccatc
     8041 gtgacgattg gagtggctaa aatcagcctc tacgagacca tgttcgaagt taagaagagc
     8101 agacgggtgc ctgtttttaa aatctatcta agatctttca agcaaaatct gaaactaggt
     8161 cttcagctgg gtttaatgga gttaggaatt gtgtttctta ccctttcaga tctctatctt
     8221 ttctggggtc aaacagctct gcccttccaa ttgctgaaag ccatttgtct aggcattctg
     8281 attttcctta cgattgtgat gttggctagc tatccaatcg cggcacgtta tgatttaact
     8341 tggaaagaag tgttacaaaa agggcttatc ttggctagtt ttaactttcc ttggttcttc
     8401 ctcatgttag ccattcttgt cctcattgtg atggttcttt atctgtccgc cttcagtcta
     8461 ctcttaggtg gctcagtctt cctacttttt gggtttggac tattggtctt tatccagact
     8521 ggattgatgg agaaaatttt cgcaaaatac caataggagc cttatttctg aaactacttt
     8581 caaaggctcc aaacgctatt ctataagcga gaaactaaaa tctaagtgtc tataagatat
     8641 tgaaagcctt ttcggtaaag tgtatactaa agaagtaaag aaaaatctgc tttagcagaa
     8701 aataaaaata ataggagaaa atctatgtca gatttgaaaa aatacgaagg tgtcattcca
     8761 gccttctacg catgttatga tgatcaagga gaagtaagcc cagaacgtac gcgtgccttg
     8821 gttcaatact tcattgataa aggtgttcaa ggtctttatg tcaatggttc ttctggtgaa
     8881 tgtatctacc aaagcgttga agatcgcaag ttgattttgg aagaagtcat ggcggtagcc
     8941 aaagataaat tgaccattat tgcccatgtt gcttgcaata atactaaaga tagtatggaa
     9001 cttgctcgcc atgctgaaag cttgggagta gatgctattg caacgattcc accaatttat
     9061 ttccgcttgc cagaatactc agttgccaaa tactggaacg atatcagttc tgcagctcca
     9121 aacacagact acgtgattta caacattcct caattggcag gggttgcttt gactccaagc
     9181 ctttacacag aaatgttgaa aaatcctcgt gttatcggtg tgaagaactc ttctatgcca
     9241 gttcaagata tccaaacctt tgtcagcctt ggtggagaag accatatcgt ctttaatggt
     9301 cctgatgagc agttcctagg aggacgcctc atgggggcta gggctggtat cggtggtact
     9361 tatggtgcta tgccagaact cttcttgaaa ctcaatcagt tgattgcgga taaggaccta
     9421 gaaacagcgc gtgaattgca gtatgctatc aacgcaatca ttggtaaact cacttctgct
     9481 catggaaata tgtacggtgt catcaaagaa gtcttgaaaa tcaatgaagg cttgaatatt
     9541 ggatctgttc gttcaccatt gacaccagtg actgaagaag atcgtccagt tgtagaagcg
     9601 gctgctgcct tgattcgtga aaccaaggag cgcttcctct aatctaaaag gaggtattta
     9661 tgacatatta cgttgcaatt gatatcggtg gaaccaacat caagtatggt ttggttgatc
     9721 aagaggggca acttcttgaa tcgcatgaaa tgccaactga ggcgcataag ggtggacctc
     9781 atatcttaca aaagaccaaa gatatcgtag ctagttattt agaaaaaggc ccagtagcag
     9841 gtgttgccat atcttctgct gggatggtgg atccggataa gggtgagatt ttctatgctg
     9901 ggccgcaaat ccctaactac gcaggcaccc agttcaaaaa ggaaatcgaa gaaagcttta
     9961 ctattccttg tgagattgaa aatgatgtca actgtgcagg tcttgctgag gcagtatctg
    10021 gttcaggcaa gggagcaagt gtgacacttt gcttgaccat tggaacaggt atcggtggtt
    10081 gcttgattat ggataggaaa gtcttccatg gttttagcaa ttcagcctgt gaagtcgggt
    10141 atatgcatat gcaggatgga gcttttcagg atctcgcttc tacaacagct ttagtgaaat
    10201 atgtagctga agcccatgga gaagatgttg atcagtggaa tggccgacgt atctttaagg
    10261 aagctactga aggaaacaaa atctgcatgg aaggcattga ccgtatggtt gactatctag
    10321 gaaaaggtct ggcaaatatt tgctacgttg ccaatccaga agtggttatt cttggtggtg
    10381 gtatcatggg gcaagaggct atcctcaaac ctaagatccg cacagccttg aaagaggctt
    10441 tggtaccaag tttagcagaa aaaacacgat tagaatttgc ccatcaccaa aatacagcag
    10501 ggatgttggg tgcatattat cattttaaga caaaacaatc ctagtttggc tcagccaaac
    10561 taggattttc ttacacgttt ttgtctacga tagccgttga gttttttatt ttcccagtag
    10621 ctattaaaga ttttttcctt gctttcgcga ttgatttcca aaaagtaggc ataaatcaaa
    10681 tcgataaaga agagcatagg aagttgagcg gatattcgtt ggatatagga gggttggctg
    10741 tgggtggcta caagaacagt ctctgtatag gtctggctat ctttattggg aacacttgta
    10801 aagagtacag tctttgcccc catctccttg gcatctaata gactatctaa aatagaagga
    10861 gttgagcctg aaagtgagaa gcccagtact agacaatttc catccatgat gctggttgtc
    10921 caggcaaagc cgtcttggtc tgtcaaagct tcgcagacca cacctagtcg cataaaacgt
    10981 aatttcattt cacgggcgac gaggccagaa ctccctgttc caaagaagta gatacgctca
    11041 gcatcttcga ttagctgggc aattcgctct agttggattt cgtcaatcaa gtcttgtgtt
    11101 tgttccctca tattgctata acttctgagg actcgtttgg tcagtggact gtgcttggag
    11161 acttggttgg cttgattttc tgcctgatgt tggtattgga aaataaattc tcggtagcca
    11221 gtaaagccac actttttagc aaagcgggtc aaagcagctt gagaaatatg taatttttgg
    11281 gtgacttgtt gagaagataa atcatctgta atcgtttcag cttgcaaaaa atagcgagcg
    11341 atttcttgct ctaggtctgt catttcttca aaatgtgaat caatgatagt tgcgatatct
    11401 ggtttgtcca tagggaaagc tcctttacat gagtcatact ggaagactag atcagggaat
    11461 agtcacactt cattataaca cataatataa ggatagataa ataaaaacgc atttctgttt
    11521 taaaaacgaa aaaatcgaaa aagcttcttt cttttccata attttctact caaattgtgg
    11581 tacaattaag agtaagattt taagttagaa atgagactga tttgtatgag aaaatttaac
    11641 agccattcga ttccgattcg gcttaattta ttgttttcaa tcgtcatttt actctttatg
    11701 accattattg gtcgtttgtt gtatatgcag gttttgaaca aggattttta cgaaaaaaag
    11761 ctagcctcag ctagtcagac caagattaca agcagttcag cccgtgggga aatttatgat
    11821 gctagtggaa aacctttggt agaaaatacg ttaaagcagg ttgtttcctt tacgcgtagc
    11881 aataaaatga cggctacaga cttaaaagaa acagctaaaa agttactgac ttatgtgagc
    11941 atcagttctc caaatttgac agaacgccag ctggcggatt actatttggc tgatcctgaa
    12001 atctataaaa aaacagtgga agctctccca agtgagaaac gcttggattc agatggcaat
    12061 cgtctatccg aatcagaact gtataacaat gcggtcgata gtgtccaaac aagtcaacta
    12121 aactatacag aggatgaaaa gaaagaaatc tatcttttta gtcagttaaa tgctgttgga
    12181 aactttgcga caggaaccat tgctacagat cctctaaatg attctcaggt ggctgttatt
    12241 gcctctattt caaaggagat gcctggcatt agtatttcta cttcttggga tagaaaggtt
    12301 ttggaaactt ccctttcttc tatagttggg agtgtatcca gtgaaaaagc tggtctccca
    12361 gcggaagaag cagaagccta tcttaaaaaa ggctattctc taaatgatcg tgtaggaacc
    12421 tcctatttgg aaaagcaata tgaagagacc ttacaaggaa aacgctcggt aaaagaaatc
    12481 catctggata aatatggcaa tatggaaagc gtggatacaa ttgaggaagg tagtaaggga
    12541 aacaatatca aactgaccat tgatttggct ttccaagata gcgtggatgc tttactgaaa
    12601 agttatttca attccgagct agaaaatggt ggagccaagt attctgaagg tgtctatgca
    12661 gtcgccctta acccaaaaac aggtgcggtt ttgtctatgt cagggattaa acatgacttg
    12721 aaaacgggag agttgacgcc tgattccttg ggaacggtaa ccaatgtctt tgttccaggt
    12781 tcggttgtca aggcggcgac catcagctca ggttgggaaa atggagtctt gtcaggaaac
    12841 cagaccttga cagaccagtc cattgtcttc caaggttcag ctcccatcaa ttcttggtat
    12901 actcaggctt acggttcatt ccctatcaca gcggtccaag ctctggagta ttcatcaaat
    12961 acctatatgg tccaaacagc cttaggtctt atggggcaaa cctatcaacc caatatgttt
    13021 gtcggcacca gcaatctaga gtctgctatg gagaaactgc gttcaacctt tggcgaatat
    13081 ggcttgggta ctgcgacagg aattgaccta ccagatgaat ctactggatt tgttcccaaa
    13141 gagtatagct ttgctaatta cattactaat gcctttgggc agtttgataa ctatacgccg
    13201 atgcagttgg ctcagtatgt agcaactatt gcaaataatg gtgttcgtgt ggctcctcgt
    13261 attgttgaag gcatttatgg taataatgat aagggaggac tgggtgactt gattcagcaa
    13321 ctgcaaccga cagagataaa taaggtcaat atatccgact ccgatatgag catcttgcac
    13381 caaggttttt atcaggttgc ccatggtact agtggattga caactggacg tgccttttca
    13441 aatggcgcct tggtatccat tagcggaaaa acaggtacag ccgaaagcta tgtggcagat
    13501 ggtcagcaag caaccaatac caatgcggtg gcctatgccc catctgataa tccccaaatc
    13561 gctgttgcag tggtctttcc tcataatacc aatctaacaa atggtgtagg accttccatt
    13621 gcgcgtgaca ttatcaatct gtatcaaaaa taccatccaa tgaactagaa aggaaattat
    13681 gctttatcca acacctattg ccaagttgat tgacagttat tctaagttac caggtatcgg
    13741 gattaagacg gctacgcgtc tggcctttta tacgattggg atgtctgctg atgatgtcaa
    13801 tgaatttgca aaaaatctcc tttctgctaa gagagaattg acatattgtt ctatttgtgg
    13861 acgtttgaca gacgacgatc cttgttctat ctgtactgat ccgactcgtg accagacaac
    13921 aattttagtt cttgaggata gtagagatgt ggcagccatg gaaaatatcc aagaatacca
    13981 tggactctat catgtccttc atggcctcat ttctcctatg aatggtatca gtccggacga
    14041 tatcaatctc aagagcctta tgactcgtct tatggatagt gaagtttcag aagtgattgt
    14101 ggcgactaat gctacagcgg atggtgaagc gacttccatg tatctttcac gtttgctcaa
    14161 gccggctggt atcaaggtta cgcgtctagc acgaggtctc gctgtgggag cggacattga
    14221 gtatgcggac gaagtgacac tcttacgagc gattgaaaat cggacagagt tgtaagtgta
    14281 ggcaaattta cgaactccat tcatttataa aaaatcaaag aggctgaaaa tcgttcctat
    14341 cggcctcttt ttgtatagtg tgatgagtag gatcaggttc aagttttaaa aaaccaagca
    14401 aatatgatat actaaagagc gagtattcta gtagaattag gacaaataat atgaaacaaa
    14461 cgattattct tttatatggt ggacggagtg cggaacgcga agtctctgtc ctttcagctg
    14521 agagtgtcat gcgtgcggtc aattacgacc gtttcacagt caagactttc tttatcagtc
    14581 agtcaggtga ctttatcaaa acacaggaat ttagtcatgc tccggggcaa gaagaccgtc
    14641 tcatgaccaa tgaaaccatt gattgggata agaaagttgc accaagtgct atctacgaag
    14701 aaggtgcagt ggtctttcca gtccttcacg ggccaatggg agaagatggc tctgttcaag
    14761 gattcttgga agttttgaaa atgccttacg ttggttgcaa cattttgtca tcaagtcttg
    14821 ccatggataa aatcacgact aagcgtgttc tggaatctgc tggtattgcc caagttcctt
    14881 atgtggctat cgttgaaggc gatgatgtga ctgctaaaat cgctgaagtg gaagaaaaat
    14941 tggcttatcc agtcttcact aagccgtcaa acatggggtc tagtgtcggt atttctaagt
    15001 ctgaaaacca agaagaactc cgtcaagcct taaaacttgc cttccgatat gacagccgtg
    15061 tcttggttga gcaaggagtg aatgcccgtg aaattgaggt tggcctcttg ggtaactacg
    15121 atgtcaagag cacgctacct ggagaagttg tcaaggacgt tgccttttat gactacgatg
    15181 ccaagtatat tgataacaag attactatgg atattcctgc caaaatcagt gatgatgtgg
    15241 tggctgtcat gcgtcaaaat gcagaaacag ccttccgtgc cattggtggc cttggtctat
    15301 ctcgttgcga tttcttctat acagataagg gagagatttt tctcaacgag ctcaatacca
    15361 tgccaggttt tacccagtgg tctatgtacc cactactttg ggacaatatg gggatcagct
    15421 acccagaact aatcgagcgt ttggttgacc ttgccaagga aagttttgac aagcgcgaag
    15481 cgcatttgat ataaaatgaa agagagggta gaagccagaa ccatcactgc acggtgacta
    15541 gagttctcgg acttcagccc tttttaaagg agtagaaatg aaattaacaa tccatgaaat
    15601 tgcccaagtt gttggagcca aaaatgatat cagtatcttt gaggacaccc agttagaaaa
    15661 agctgagttt gatagtcgtt tgattggaac tggagattta tttgtgccac ttaaaggtgc
    15721 gcgtgatggc catgacttta ttgaaacagc ctttgaaaat ggtgcagcag taaccttgtc
    15781 tgagaaagag gtctcaaatc atccttacat tctagtagat gatgttttga cagcctttca
    15841 atccctagca tcctactatc ttgaaaaaac gactgttgat gtctttgctg ttacaggttc
    15901 aaatggcaag acaacgacta aggatatgtt ggcgtattta ctgtcaacaa gatacaagac
    15961 ctacaaaaca caaggcaatt acaataatga gattggcctt ccttacacag ttctccacat
    16021 gcctgaagga acagaaaagt tggtcttgga gatggggcag gaccacttgg gagatattca
    16081 tctcttgtct gaattggctc gtccaaaaac agccatcgtg accttggttg gagaagctca
    16141 tttggccttt ttcaaagatc gttctgagat tgctaaagga aaaatgcaaa ttgcagacgg
    16201 aatggcttca ggttccttgc ttttagcgcc ggctgaccct atcgtagagg actatttgcc
    16261 aactgataaa aaggtggttc gttttggtca aggagcagag ctggaaatta ctgacttggt
    16321 tgagcgcaaa gatagtctga ccttcaaggc caatttctta gagcaagtcc ttgatttgcc
    16381 agtaactggc aagtataatg cgacaaatgc tatgattgca tcctatgttg ccttgcaaga
    16441 aggagtttca gaggagcaaa ttcatcaggc cttccaagat cttgaattga cgcgtaaccg
    16501 taccgaatgg aagaaagcag ccaatggagc agatatcctg tctgatgtat acaatgccaa
    16561 tccaactgct atgaagttga ttttagagac tttctctgcc attccagcca atgaaggtgg
    16621 caagaaaatt gcggttttag cggacatgaa ggaactgggt aaccagtcag ttcaacttca
    16681 taatcagatg attttgagcc tttctccaga tgtgcttgat accgtgattt tctatggaga
    16741 agacattgct gaattagccc aattggccag tcaaatgttc ccaattggcc acgtttacta
    16801 cttcaagaaa acagaagacc aagaccaatt tgaagaccta gtcaagcagg tcaaggaaag
    16861 cctcagtgcc aatgatcaaa tcttgctcaa gggctctaac tctatgaacc tagctatgtt
    16921 ggtagaaagt ttagaaaatg aaaccaagtg attttgttaa gtatctgcaa agaatgattg
    16981 cccttacaga tactggctta acctttacaa aagatccttt tgaccgtgag cgctacgagg
    17041 acttgcgaag tctgttatct gaaatgttga atcagggatc agacctggat gcagaagaag
    17101 tagcagaagt cttgaaacca acttcagctt atgcgactcc cttaatggac gtccgtgctt
    17161 ggattgttga ggatgagaag atttgtctgg ttaggggaca aggagagggt agttgggctt
    17221 tgccaggtgg ctttggtgaa gtcggctatt ctccaactga aaatattctc aaggaaattg
    17281 aagaagaaac cggttttaaa gccaaagttg aaagactgct agctgttttt gatatcaatc
    17341 gtttccaact acagagcaaa caatatgcaa agtttgtttt tgaatgtaag cttctcgatg
    17401 gacaattcca agaaaatcaa gaaattgcag accttcaatt ttttgccatt gatcaactgc
    17461 cagtcttatc tgaaaaacgc attaccaagg agcaaataga gattctttgg caggtttatc
    17521 aaggtcagag ggagcaatat cttgactaag aagatgatta tcgtattttt aaatccattt
    17581 ttaacaacta gcatggtata ataatatgca ggaaaatttt gaattatgag gaagactaga
    17641 tgaatttatg ggatattttc tttacgactc aggcaaccaa gccgcccaaa tttgaccttt
    17701 tttggtatgt tagcctattt acgctcttag ccttaacctt ttatacagcc catcgctatc
    17761 gtgaaaagaa ggtttaccaa cgatttttcc aaatcttgca gactgttcag ttaatccttc
    17821 tttatggttg gtactgggtc aatcatatgc cactgtcaga aagcctaccc ttttaccatt
    17881 gccgtatggc tatgtttgtg gtactcttgc ttcctggtca atccaaatat aaacaatact
    17941 ttgcattatt gggaacattt gggacattag cagcctttgt ttatccagtg ccagatgctt
    18001 acccttttcc acatatcacc attctatcct ttatctttgg tcatttagca ctcttgggga
    18061 actctctagt ttatctattg agacagtata atgcgcgatt gctggatgtg aagggaattt
    18121 ttctcatgac ctttgcccta aatgccttga tttttgtggt caatttggtg acaggtggcg
    18181 attacggatt tttgacaaaa ccgccattgg ttggggatca cggtctagta gctaattatt
    18241 tacttgtttc aattgtgctg gtagctacta tcagtttgac taagaaaatc ttagaattct
    18301 ttttagctca agaagcagaa aaaatgattg taaaggaagc ttaacacaga gctttctttt
    18361 ttgctcttag agagttttta caatcagctt ataaaataag aatttctgaa tagacaaact
    18421 caaaaaatgg ctgggaaatt taggaaaaaa gcaagcacga ttaaattttt tgtgttataa
    18481 tattttgtga atagctatgc ctatgtttag ctatggaata atacgaagtg cgaaacttgg
    18541 aagatagaga ggaagcgatg taatggctag agaaggcttt tttacaggtc tagatattgg
    18601 aacaagctct gtcaaggtgc ttgtggccga gcagagaaat ggtgaattaa atgtaattgg
    18661 cgtgagtaat gccaaaagta aaggtgtaaa ggatggaatt attgttgata ttgatgcagc
    18721 agcaactgct atcaagtcag ccatttccca agcggaagaa aaggcaggca tttcgattaa
    18781 atcagtaaat gtcggcttgc ctggtaatct tttgcaggta gaaccaactc aggggatgat
    18841 tccagtaaca tctgatacta aggaaattac ggatcaagat gttgaaaatg ttgtcaaatc
    18901 agctttgaca aagagtatga cacctgaccg tgaagtcatt acctttattc ctgaagaatt
    18961 tattgtggat ggtttccaag ggattcgtga cccacgtggc atgatggggg ttcgccttga
    19021 aatgcgtggt ttgctttata caggacctcg tactatcttg cacaatttgc gtaagacggt
    19081 tgagcgtgca ggtgttcagg ttgaaaatgt tatcatttca ccactagcaa tggttcagtc
    19141 tgttttgaac gaaggggaac gtgaatttgg tgctacagtg attgatatgg gggcaggtca
    19201 aacgactgtc gctacaatcc gtaatcaaga actccagttc acacatattc tccaagaagg
    19261 tggagattat gtaactaaag atatctccaa ggttttgaaa acctctcgca aattagcgga
    19321 aggcttgaaa ctgaattacg gggaagccta tccgcctctt gcaagcaaag aaaccttcca
    19381 agtagaggtt attggagaag tagaagcagt cgaagtgacg gaagcctact tgtcagaaat
    19441 tatttctgca cgaatcaagc acatccttga acaaatcaag caagaattag atagaaggcg
    19501 tctattggac ctccctggtg gtattgtctt aatcggtggg aatgccattt taccaggtat
    19561 ggttgagctt gctcaggaag tctttggcgt ccgtgtcaag ctttatgttc caaatcaagt
    19621 tggtatccgt aatccagcct ttgcgcatgt gattagttta tcagaatttg cgggtcaatt
    19681 aacagaagtt aatcttttgg ctcagggagc gataaaaggt gagaatgact taagtcatca
    19741 gccaattagt tttggtggga tgctgcaaaa aacagctcag tttgtacaat caacgcctgt
    19801 tcaaccagct cctgctccag aagtagagcc ggtggcgcct acagaaccaa tggcggattt
    19861 ccaacaagct tcacaaaata aaccgaaatt agcagatcgt ttccgtggct tgatcggaag
    19921 catgtttgac gaataaagag gaaaaataaa ttatgacatt ttcatttgat acagctgctg
    19981 ctcaaggggc agtgattaaa gtaattggtg tcggtggagg tggtggcaat gccatcaacc
    20041 gtatggtcga cgaaggtgtt acaggcgtag aatttatcgc agcaaacaca gatgtacaag
    20101 cattgagtag tacaaaagct gagactgtta ttcagttggg acctaaattg actcgtggtt
    20161 tgggtgcagg aggtcaacct gaggttggtc gtaaagccgc tgaagaaagc gaagaaacac
    20221 tgacggaagc tattagtggt gccgatatgg tcttcatcac tgctggtatg ggaggaggct
    20281 ctggaactgg agctgctcct gttattgctc gtattgccaa agatttaggt gcgcttacag
    20341 ttggtgttgt aacacgtccc tttggttttg aaggaagtaa gcgtggacaa tttgctgtag
    20401 aaggaatcaa tcaacttcgt gagcatgtag acactctatt gattatctca aacaacaatt
    20461 tgcttgaaat tgttgataag aaaacaccgc ttttggaggc tcttagcgaa gcggataacg
    20521 ttcttcgtca aggtgttcaa gggattaccg atttgattac caatccagga ttgattaacc
    20581 ttgactttgc cgatgtgaaa acggtaatgg caaacaaagg gaatgctctt atgggtattg
    20641 gtatcggtag tggagaagaa cgtgtggtag aagcggcacg taaggcaatc tattcaccac
    20701 ttcttgaaac aactattgac ggtgctgagg atgttatcgt caacgttact ggtggtcttg
    20761 acttaacctt gattgaggca gaagaggctt cacaaattgt gaaccaggca gcaggtcaag
    20821 gagtgaacat ctggctcggt acttcaattg atgaaagtat gcgtgatgaa attcgtgtaa
    20881 cagttgttgc aacgggtgtt cgtcaagacc gcgtagaaaa ggttgtggct ccacaagcta
    20941 gatctgctac taactaccgt gagacagtga aaccagctca ttcacatggc tttgatcgtc
    21001 attttgatat ggcagaaaca gctgaattgc caaaacaaaa tccacgtcgt ttggaaccaa
    21061 ctcaggcatc tgcttttggt gattgggatc ttcgccgtga atcgattgtt cgtacaacag
    21121 attcagtcgt ttctccagtc gagcgctttg aagccccaat ttcacaagat gaagatgaat
    21181 tggatacacc tccatttttc aaaaatcgtt aagtaaatga atgtaaaaga aaatacagaa
    21241 cttgtttttc gagaagttgc agaggctagt ctgagtgctc atcgagagag tggttcggtc
    21301 tctgtcattg cagttaccaa gtatgtagat gtaccgacag cggaagcctt gcttccgcta
    21361 ggtgttcatc atatcggtga aaatcgtgta gataagtttc tggaaaaata tgaagcttta
    21421 aaagatcgag atgtgacttg gcatttgatt ggtaccttgc aaagacgtaa ggtgaaagat
    21481 gtcattcaat acgttgatta tttccatgca ttggactcag taaagctagc aggggaaatt
    21541 caaaaaagaa gtgaccgagt catcaagtgt ttccttcaag taaatatttc taaagaagaa
    21601 agcaaacacg gtttttcgag agaggaactg ctggaaatct tgccagagtt agccagacta
    21661 gataagattg aatatattgg tttaatgacg atggcacctt ttgaggctag cagtgagcag
    21721 ttgaaagaga ttttcaaggc ggcccaagat ttacaaagag aaattcaaga gaaacaaatt
    21781 ccaaatatgc ctatgaccga gttaagtatg ggaatgagtc gtgattataa agaagcgatt
    21841 caattcggtt ccacttttgt tcgtataggt acatcatttt ttaagtagga gagaaccatg
    21901 tctttaaaag atagattcga tagatttata gattatttta cggaggatga ggattcaagt
    21961 ctcccttatg aaaaaagaga tgagcctgtg tttacttcag taaattcttc acaggaaccg
    22021 gctctcccaa tgaatcaacc ttcacagtcg gctggtacaa aagagaacaa tatcaccaga
    22081 cttcatgcaa gacaacagga attggcaaat cagagtcagc gtgcaacgga taaggtcatt
    22141 atagatgttc gttatcctag aaaatatgag gatgcaacag aaattgttga tttattggca
    22201 ggaaacgaaa gtatcttgat tgactttcag tatatgacag aggtgcaggc tcgtcgttgt
    22261 ttggactatt tggatggagc ttgtcatgtt ttagctggaa atttgaaaaa ggtagcttct
    22321 accatgtatt tgttgacacc agtgaacgtt attgtaaatg ttgaagatat ccgtttacca
    22381 gatgaagatc aacagggtga gttcggtttt gatatgaagc gaaatagagt acgataatga
    22441 tttttttaat tcgtatgatt tataatgcag tggatattta ctccctgatt ttggtagcct
    22501 tcgctgtcat gtcttggttt ccaggtgcct acgaatccag tttaggtcgt tggattgtag
    22561 cgttggtgaa accagtgctt gctcccttgc aacgcctgcc tttacagata gcgggtcttg
    22621 atttatctgt ttgggttgcg attgttttgg ttcgattttt aggagaaaac ctagtgcgtt
    22681 ttctggcgat gataggatga ataaagggat ttatcagcat ttctccatag aagatcgtcc
    22741 atttcttgac aagggaatgg aatggataaa gaaggtagaa gatagctatg ctcctttttt
    22801 aactcctttt atcaatcctc atcaggagaa gctattaaag attttggcca aaacctatgg
    22861 tcttgcttgt agcagtagtg gggaattcgt ctcgagtgag tatgttcgag ttttattata
    22921 cccagattat ttccaaccag agttttcaga ttttgaaata tctctccagg aaattgtgta
    22981 ttccaataaa tttgaacatt taacgcatgc taagatttta gggacagtca tcaatcaatt
    23041 agggattgaa cggaaacttt ttggagatat cctagtagat gaagaacggg cgcagattat
    23101 gattaatcag cagtttcttc ttctctttca agatggacta aagaaaattg gtcgtatacc
    23161 tgtttcgctg gaggaacgtc ctttcaccga gaaaatagat aagctagaac agtatcgaga
    23221 actggattta tctgtgtcta gttttcgatt agatgttctt ttatcaaatg ttttgaaact
    23281 atctaggaat caagcaaacc agttgattga aaagaaactt gtccaagtaa attatcatgt
    23341 ggtagacaaa tcagattaca ctgttcaagt tggagacttg attagtgtga gaaaatttgg
    23401 tcgcttgaga ttacttcaag ataagggaca aacgaaaaaa gagaagaaaa aaataaccgt
    23461 ccagttatta ttaagtaagt gaggaataga atgccaatta catcattaga aataaaggac
    23521 aagacttttg gaactcgatt cagaggtttt gatccagaag aagtcgatga atttttagat
    23581 attgtggttc gtgattacga agatcttgtg cgtgcgaatc atgataaaaa tttgcgtatt
    23641 aagagtttag aagagcgttt gtcttacttt gatgaaataa aagattcatt gagccagtct
    23701 gtattgattg ctcaggatac agctgagaga gtgaaacagg cggcgcatga acgttcaaac
    23761 aatatcattc atcaagcaga gcaagatgcg caacgcttgt tggaagaagc taaatataag
    23821 gcaaacgaga ttcttcgtca agcaactgat aatgctaaga aagtcgctgt tgaaacagaa
    23881 gaattgaaga acaagagccg tgtcttccac caacgtctca aatctacaat tgagagtcag
    23941 ttggctattg ttgaatcttc agattgggaa gatattctcc gtccaacagc tacttatctt
    24001 caaaccagtg atgaagcctt taaagaagtg gttagcgaag tacttggaga accgattcca
    24061 gctccaattg aagaagaacc aattgatatg acacgtcagt tctctcaagc agaaatggca
    24121 gaattacaag ctcgtattga ggtagccgat aaagaattgt ctgaatttga agctcagatt
    24181 aaacaggaag tggaagctcc aactcctgta gtgagtcctc aagttgaaga agagcctctg
    24241 ctcatccagt tggcccaatg tatgaagaac cagaagtagc tccaatgcat ccgataggtc
    24301 caacaccagc tacagaaact gttgattcaa taccgggatt tgaagcaccg caagaatctg
    24361 ttacaatttt ataagaaata ttctgagaac aatatcttat ccttatattt ccagcgagca
    24421 ggagatggtg tgagtcctgt aatccctatt gataagatta tcctctcaaa aactcaagtc
    24481 tgaagctagt aagatttgac gtttcccacg ttacgggata agagggagaa agactaaatc
    24541 tttttccgaa taaaggtggt accacgattt tcgtcctttt tggaagtcgt ggtttttaat
    24601 ttgttattat ttataaagga gataccatga aactcaaaga cacccttaat cttgggaaaa
    24661 ctgaattccc aatgcgtgca ggccttccta ccaaagagcc agtttggcaa aaggaatggg
    24721 aagatgcaaa actttatcaa cgtcgtcaag aattgaacca aggaaaacct catttcacct
    24781 tgcatgatgg ccctccatac gctaacggaa atatccacgt tggacatgct atgaacaaga
    24841 tttcaaaaga tatcattgtt cgttctaagt ctatgtcagg attttacgca ccatttattc
    24901 ctggttggga tactcatggt ctgccaatcg agcaagtctt gtcaaaacaa ggtgtcaaac
    24961 gtaaagaaat ggacttggtt gagtacttga aactttgccg tgagtacgct ctttctcaag
    25021 tagataaaca acgtgaagat tttaaacgtt tgggtgtttc tggtgactgg gaaaatccat
    25081 atgtgacctt gactcctgac tatgaagcag ctcaaattcg tgtatttggt gagatggcta
    25141 ataagggtta tatctaccgt ggtgctaagc cagtttactg gtcatggtca tctgagtcag
    25201 cacttgctga agcagagatt gaataccatg acttggtttc aacttccctt tactatgcca
    25261 acaaggtaaa agatggcaaa ggagttctag atacagatac ttatatcgtt gtctggacaa
    25321 cgactccatt taccatcaca gcttctcgtg gtttgacggt tggtgcagat attgattacg
    25381 ttttggttca acctgctggt gaagctcgta agtttgtcgt tgctgctgaa ttattgacta
    25441 gcttgtctga gaaatttggc tgggctgatg ttcaagtttt ggaaacttac cgtggccaag
    25501 aactcaacca catcgtaaca gaacacccat gggatacagc tgtagaagag ttggtaattc
    25561 ttggtgacca cgttacgact gactctggta caggtattgt ccatacagcc cctggttttg
    25621 gtgaggacga ttacaatgtt ggtattgcta ataatcttga agtcgcagtg actgttgatg
    25681 aacgtggtat catgatgaag aatgctggtc ctgaatttga aggtcaattc tatgaaaagg
    25741 tagttccaac tgttattgaa aaacttggta acctccttct tgcccaagaa gaaatctctc
    25801 actcatatcc atttgactgg cgtactaaga aaccaatcat ctggcgtgca gttccacaat
    25861 ggtttgcctc agtttctaaa ttccgtcaag aaatcttgga cgaaattgaa aaagtgaaat
    25921 tccactcaga atggggtaaa gtccgtcttt acaatatgat ccgtgaccgt ggtgactggg
    25981 ttatctctcg tcaacgtgct tggggtgttc cacttcctat cttctacgct gaagatggta
    26041 cagctatcat ggtagctgaa actattgaac acgtagctca actttttgaa gaatatggtt
    26101 caagcatttg gtgggaacgt gatgccaaag acctcttgcc agaaggattt actcatccag
    26161 gttcaccaaa cggcgagttc aaaaaagaaa ctgatatcat ggacgtttgg tttgactcag
    26221 gttcatcatg gaatggagtg gtggtaaacc gtcctgaatt gacttaccca gccgaccttt
    26281 acctagaagg ttctgaccaa taccgtggtt ggtttaactc atcacttatc acatctgttg
    26341 ccaaccatgg cgtagcacct tacaaacaaa tcttgtcaca aggttttgcc cttgatggta
    26401 aaggtgagaa gatgtctaaa tctcttggaa atactattgc tccaagcgat gttgaaaaac
    26461 aattcggtgc tgaaatcttg cgtctctggg taacaagtgt tgactcaagc aatgacgtgc
    26521 gtatctctat ggatatcttg agccaagttt ctgaaactta ccgtaagatt cgtaacactc
    26581 ttcgtttctt gattgccaat acatctgact ttaacccagc tcaagataca gtcgcttacg
    26641 atgagcttcg ttcagttgat aagtacatga cgattcgctt taaccagctt gtcaagacca
    26701 ttcgtgatgc ctatgcagac tttgaattct tgacgatcta caaggccttg gtgaacttta
    26761 tcaacgttga cttgtcagcc ttctaccttg attttgccaa agatgttgtt tacattgaag
    26821 gtgccaaatc actggaacgc cgtcaaatgc agactgtctt ctatgacatt cttgtcaaaa
    26881 tcaccaaact cttgacacca atccttcctc acactgcgga agaaatctgg tcatatcttg
    26941 agtttgaaac agaagacttc gtccaattgt cagaattacc agaagttcaa acttttgcta
    27001 accaagaaga aatcttggat acatgggcag ccttcatgga ctttcgtgga caagcacaaa
    27061 aagccttgga agaagctcgt aatgcaaaag ttatcggtaa atcacttgaa gcacacttga
    27121 cagtttatcc aaatgaagtt gtgaaaactc tactcgaagc agtaaacagc aatgtagcac
    27181 aacttttgat cgtgtctgag ttgaccatcg cagaaggacc agctccggaa gctgccctta
    27241 gcttcgaaga tgtagccttc acagttgaac gtgctactgg tgaagtatgt gaccgttgcc
    27301 gtcgtatcga cccaacaaca gcagaacgca gctaccaggc agttatctgt gaccactgtg
    27361 caagcatcgt agaagaaaac tttgcggaag cagtcgcaga aggatttgaa gagaaataag
    27421 attgaaaagt ctaggcaaaa ttcaatttga gaagaaaaga caactaattt tatagtctat
    27481 taaacgcatt gtatcacgtt tttgaatacc tgatatgatg cgttttttat ttattttaaa
    27541 aatttgcgag gtatgacttt ttatactcaa caagaatcaa agagaaactt agcaagctaa
    27601 cagtagtaag ataaaatagg aatttgatat tagggataag a
//
LOCUS       DBJKQU010000025        25561 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.025, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000025 DBJKQU010000000
VERSION     DBJKQU010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25561
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.025"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(<1..275)
                     /locus_tag="ACSUUC_001204"
     CDS             complement(<1..275)
                     /locus_tag="ACSUUC_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHQ8054420.1"
                     /translation="MRNKIWYSSSMNDEASKQLTDARFKRLVGVQRTTFEEILAVLKT
                     AYQLKHAKGGRKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESN"
     gene            complement(626..1486)
                     /locus_tag="ACSUUC_001205"
     CDS             complement(626..1486)
                     /locus_tag="ACSUUC_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HHQ8054421.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1502..2779)
                     /gene="spxR"
                     /locus_tag="ACSUUC_001206"
     CDS             complement(1502..2779)
                     /gene="spxR"
                     /locus_tag="ACSUUC_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HHQ8054422.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2772..3323)
                     /locus_tag="ACSUUC_001207"
     CDS             complement(2772..3323)
                     /locus_tag="ACSUUC_001207"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8054423.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3339..4598)
                     /locus_tag="ACSUUC_001208"
     CDS             complement(3339..4598)
                     /locus_tag="ACSUUC_001208"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HHQ8054424.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGVSIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGTSVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(5753..5911)
                     /locus_tag="ACSUUC_001209"
     CDS             complement(5753..5911)
                     /locus_tag="ACSUUC_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054425.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(5921..7231)
                     /gene="obgE"
                     /locus_tag="ACSUUC_001210"
     CDS             complement(5921..7231)
                     /gene="obgE"
                     /locus_tag="ACSUUC_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HHQ8054426.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(7295..7429)
                     /locus_tag="ACSUUC_001211"
     CDS             complement(7295..7429)
                     /locus_tag="ACSUUC_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HHQ8054427.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(7488..7664)
                     /locus_tag="ACSUUC_001212"
     CDS             complement(7488..7664)
                     /locus_tag="ACSUUC_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HHQ8054428.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(7695..9020)
                     /locus_tag="ACSUUC_001213"
     CDS             complement(7695..9020)
                     /locus_tag="ACSUUC_001213"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HHQ8054429.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRSSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(9036..10079)
                     /gene="cpoA"
                     /locus_tag="ACSUUC_001214"
     CDS             complement(9036..10079)
                     /gene="cpoA"
                     /locus_tag="ACSUUC_001214"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HHQ8054430.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(10194..10523)
                     /locus_tag="ACSUUC_001215"
     CDS             complement(10194..10523)
                     /locus_tag="ACSUUC_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HHQ8054431.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10537..11646)
                     /gene="rpoD"
                     /locus_tag="ACSUUC_001216"
     CDS             complement(10537..11646)
                     /gene="rpoD"
                     /locus_tag="ACSUUC_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HHQ8054432.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(11649..13409)
                     /gene="dnaG"
                     /locus_tag="ACSUUC_001217"
     CDS             complement(11649..13409)
                     /gene="dnaG"
                     /locus_tag="ACSUUC_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HHQ8054433.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(13499..14257)
                     /locus_tag="ACSUUC_001218"
     CDS             complement(13499..14257)
                     /locus_tag="ACSUUC_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054434.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(14254..15120)
                     /locus_tag="ACSUUC_001219"
     CDS             complement(14254..15120)
                     /locus_tag="ACSUUC_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8054435.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMDLMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(15189..16193)
                     /gene="trpX"
                     /locus_tag="ACSUUC_001220"
     CDS             complement(15189..16193)
                     /gene="trpX"
                     /locus_tag="ACSUUC_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HHQ8054436.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(16306..16523)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16606..19302)
                     /gene="ppc"
                     /locus_tag="ACSUUC_001221"
     CDS             complement(16606..19302)
                     /gene="ppc"
                     /locus_tag="ACSUUC_001221"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HHQ8054437.1"
                     /translation="MSLQKLENYSNKSVVKEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWHNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFDSSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(19322..20551)
                     /gene="ftsW"
                     /locus_tag="ACSUUC_001222"
     CDS             complement(19322..20551)
                     /gene="ftsW"
                     /locus_tag="ACSUUC_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division peptidoglycan polymerase FtsW"
                     /protein_id="HHQ8054438.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(20695..21009)
                     /locus_tag="ACSUUC_001223"
                     /pseudo
     CDS             complement(20695..21009)
                     /locus_tag="ACSUUC_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(21457..21678)
                     /locus_tag="ACSUUC_001224"
     CDS             complement(21457..21678)
                     /locus_tag="ACSUUC_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHQ8054439.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            complement(22358..23569)
                     /locus_tag="ACSUUC_001225"
                     /pseudo
     CDS             complement(22358..23569)
                     /locus_tag="ACSUUC_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011225463.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(23571..24815)
                     /locus_tag="ACSUUC_001226"
     CDS             complement(23571..24815)
                     /locus_tag="ACSUUC_001226"
                     /EC_number="6.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HHQ8054440.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQGLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMLVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            complement(24839..>25561)
                     /gene="galE"
                     /locus_tag="ACSUUC_001227"
     CDS             complement(24839..>25561)
                     /gene="galE"
                     /locus_tag="ACSUUC_001227"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HHQ8054441.1"
                     /translation="NLLSTINILKLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLK
                     ASNPYGRTKQYIEVLLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVP
                     YITQVAIGKLPYLNIFGVDYSTPDGTCIRDYVHVNDLVYGHRKALEYIFNTDEGLYEV
                     INLGSGVGFSVFEILHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRY
                     DIMKMCQDTWKWQQKHPNGYDD"
BASE COUNT         7836 a         5544 c         4209 g         7972 t
ORIGIN      
        1 aagttgcttt cgtgaatacc aaaatcagcc gcaatttgtt cataagttcg atattctcgc
       61 acatattgaa gagtggccat aagaaggtct tctaggctta atttaggttt tcgtccacct
      121 tttgcgtgtt taagttgata agctgttttt aatacagcta atatctcttc aaaagtcgtg
      181 cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact tgcttcatca
      241 ttcatagaac tactatacca tattttattt cgcaggaagt ctaatctaaa aaaggtaaat
      301 ttaagattgg caatacgaac gttaaacaga attccatttc tctttttaga atcaaaacga
      361 caatattgtg gaatctctac aggaacaata gactgcgaca ctaaaatatc ctctcttagt
      421 tttactttac taatagtata taggaggaga gccctgaatc ctagaccctt tgttatgatg
      481 cgcttacaaa cagagttgga aaaaatctta aaagcagaaa aacgcatgat atcagcccct
      541 aacacttgat acaatgcgtt ttattatgaa aagatctact ggatttttta tcaaaataaa
      601 cttccagtag tcttttcact ttttattaat aagttccttc ttcaccttgg ctagtcaaga
      661 taacaggtcc atctttcgta atgacaaatt ggtgttcata ctgacatgac aatccaccgt
      721 caatggtctt atgcgcccaa ccagttttca tatctgtatc aatttcccaa tcgcctgtat
      781 tgatcattgg ttcaatggtt aagaccattc cttcacgaag acggagtcca cgacctgcaa
      841 taccatagtt aggaaccatt ggttcttcgt gcatagttgg gccaacacca tgaccaacca
      901 aatcacgcac tacaccgtaa ccacgacttt cagcgtattc ttgaatagcc gcaccgatat
      961 caccgatacg atttccaaca acagcttgct caataccctt gtacatagct tctttggtta
     1021 catccatcaa gtttttgact tcttcggacg gtgtaccaac agcataagcc caacatgagt
     1081 ctgctaaacc accagaatag ctctgagtgt attttttcat ttgttcaaca ttgttgaagt
     1141 ttaattttga gacatttagg tcagatttag caatgggacc tcccaaaacc atatcaactt
     1201 tgagcaaatc accatctttc aagatataat gacgagggaa agcgtgagcc acttcatcgt
     1261 taagagagca acaggtagca taaggatagt ccatcatggc accgtcaacc ccaatctgaa
     1321 gtggaaggaa attttcttct ttacaacgac ggcggacata ttcttcaact tcccacatat
     1381 ctacgcctgg cttaatcaaa tcacgtaagc ctatatgaat acttgctaga aaatcaccag
     1441 ccttgtccat agcttcgatt tcacgagctg attttaatgt tatcatcttt tctcctagtt
     1501 tctaattaat tttaacagtc acatttgctt ttgaaacaat ctggtgacca tgataaatat
     1561 cgtaatcaat tatagctgac cgtctcgtat gatgaataat ccgtgcctga atgcgcaata
     1621 tatcatctat ctgaacagcc tgcaaaaagt agatcagcat ctgctcgata atgagattgc
     1681 gaccactatt aacaactaaa tcttgggtca tgtgggtcag aatttctgcc aatacaccat
     1741 tagccaaaac tccatttttt tctagcataa agggttccac tgtaatgact acttcatcat
     1801 ggtgataaga gagcttttgt ccaatctgct cagaaaaagt tggtagagcc gaaacttggg
     1861 aacggctcat cttctccatg acatctcgtc gcgtcacaac gccaagcaaa gtttgattgc
     1921 ttcgaacaac tggtaccatt tcaaagtctt ctgcgatcat ccgttgactc acattggcaa
     1981 tatttgtcga taatccaacc aaaaatagac tacgagacat aaccttatca attgtcgtgc
     2041 ttggtgattt atcaccagcg tctctcatgg ttacaacacc aacaacgacc tgatgttgat
     2101 tgataacagg gaaacggctg ctacgattct tacgaaccaa gtccaaataa tctttaactg
     2161 tatctgtctc tcttagaaaa ccatactcat gactagggcg ataaagtttc tcaactgtca
     2221 gaatatcagt cttgatttgg acatttgaca aggctttatt gatcatggtc gcgacggtaa
     2281 aggtatcatg cttacttctt agaacaggaa tccctttttg attggccagt ttaagcacat
     2341 catcatgaac ctgaaatccc cctgtaacca gaactgcatt ttcattttcc aaggctagca
     2401 actgaatacg ggttcggtct ccgacaatca agagcccccc atcatgaagg taagacaaga
     2461 tattttgttc agtcatggca ccaattgaaa acttactaaa ctctctctct aaaccttctt
     2521 gcccagccag aacctcagaa gaagtcactt ctgcaatttc agcaaacgtt aatctctcta
     2581 tagcaacttt ctgggattta acacgaattg ttccacttct aggacgggtc tccacaattc
     2641 cacggttttc agcttcttta atagcccgat aggctgttcc atcactaact cctagatgat
     2701 tcgaaatgct acgaacactg acccttttac ctactggtaa ttcctccaaa tagcttagaa
     2761 tttcctgatg cttactcatt gaactctcct tttacatacc gaaattcaag ataatcccgc
     2821 atttttcttg tgtaacgatc acttccctta aactgacgga acaaactaaa tccagactta
     2881 agagcaactc tttggctagc tttattttca aggtgggtaa tgataaataa ttgttttaag
     2941 ccaaattcct caaaagaaag ctgacaaatt tttctaacaa cctctgtcat aaatccttgc
     3001 gaccaagcat cttttctcaa aaaatagcca agctcagctt cttttttgat ttcatctaac
     3061 ttctcaaatt taatagaacc aatcatttgt tgatttttct ggtcacaaat tgcccacact
     3121 cccaaagggg acttcataaa gtaattggcc agtgcatatt gactttcttc cagacttgcc
     3181 tgcgttggga aaataaattg aagattttct ggatttgaag ctatctcgcg gaagtcctga
     3241 ctatcactaa aaaagaaagg acgcaaatac aagcgatccg tttcaaaaaa agaaaacatt
     3301 gctaatttgg tccaaatatt cataaacacc tctacggttt aatcctcaac aagtctaata
     3361 tccgctccta aattacgtaa tttttcgata atatcagaat aaccacgtaa gataaactcg
     3421 atattggtaa tttcagtttt accttcagcc ataagcccag caatgactag tgcagcccca
     3481 gctcttaagt cggtcgcttt aacactggtc ccacgtaaat cacgtccacc cgtgtacaaa
     3541 atatgaccat ttgttgtcga aatatccgca tccatctttg ctagttcaaa aacatgattt
     3601 acacgttttt cgtaaatcgt atcgacaatt gtaccacgac cattcgctct tagtaaaaga
     3661 ggggtaagcg gttgttgcaa atcagttgca aagcctgggt aaggagctgt cttaatattg
     3721 attgctttca aattagactg ttcctcgaca aaaatgctgt cttcagatac agtcattctc
     3781 actcccattt cttccaactt agcaataaac ccttccaggt gttcgtaaag aacattattt
     3841 atacgaattc ctttaccaac tgcagcagct aaagatatat atgttccagc ttcaatgcgg
     3901 tctggaatca cctgatgacg tgtcccatgt aatctttcaa caccatcaat aatgatgata
     3961 ttagttcctg ccccacggat atgggcaccc atattattca agagagtagc tacatcaata
     4021 atctcaggtt cacgagctgc attttcaata atagtacgac catttgcttt aaccgcagca
     4081 atcatcgtat taatcgttgc tcccacacta accgtatcca tgtaaatact tacaccatga
     4141 agtcctgtat ctttagcaga taacttcatg ttatctccct cgtagctagc agtggcaccc
     4201 atagcttcaa acgccttaag gtgtaagtca atcggacgag gaccaagatc acatcctccc
     4261 ggtagaccaa ctgtcgcttc accaaaacgg cctaagaggc tcccataaaa atagtaagat
     4321 gcacgaagac tgttaatttt accataaggc attggaatat tttgaacacc tcttggatca
     4381 atctccaaga catcgtcata acgcttaaca gtagctccca tcaattccat gatttcgaca
     4441 agactggcta catccgaaat atctggaaca caatccaaag tcaccacatc atcagccaat
     4501 ataatagctg gaattaaggc cacaacacta tttttagcac cactaatagt aatttcacct
     4561 tgcagtggta atccaccatt gataacaatt tttctcattc taagttttca atactctttc
     4621 aagatttcta ataaggtctt caaaataaag tatatcataa atttatcctt ttttccatcc
     4681 ttttcaattt tattggctaa atcagagttg acgagttagt aactgaatta ctaatactca
     4741 ataaaaatca aagatcaaac taggaaacta gccgcaggtt gctcaaaaca ctgttttgag
     4801 attgtagatg gaactgacgt agtcagtatc ctacacatac ggcaaggcga tattgacgtg
     4861 atttgaagag attttcgaag agtataatct ttctcgaatc gctattgccc cttttttatc
     4921 ccctaaaact gagtaggagc taagactaga tctcttatct aagtatcgga atacggctgt
     4981 tcaactaaat tttagcaaga acttctcccc cttctctcag ttcacagaag cgttttatac
     5041 ataccgtcct atcagacaat ctattttaaa gataaccgtg actcaggatc acttctatct
     5101 gtcgttttct ctttatagtg atagacctca cgggataagt cgtacatctt tcctcgtgta
     5161 tacaagatat gagggcgtta aaaggttaca gtgaaaatag aaaatcttag tacgaattca
     5221 attactctcg tgatttacgc atataggtta cgactacctt tttggacttt agaatttgag
     5281 gccctcttat ccgctatata cgccttatta tcacgttcct gttcgtagag ccacgatttc
     5341 gctatccctt cttctgacaa ttcttatttc cagcgtcaga cttaaaacgg tctatcccca
     5401 gaccatttta atctgctacc tcacgatagt caggcttggg aatcgctatt tgactcgccg
     5461 agaactttga catcagatat actataacaa attgaaataa gaatcaaaca atttaatttt
     5521 gaaattcaaa tcaatttata acaatatagt tgattgaaac tagaatagta catctctgct
     5581 tctaaaacat tgttagaaat cgattttact gtcctgatcg atttgtcctg ttctcatttc
     5641 attttactat attttagaag atatgctgtg ctattccaga ttcagtttgc tatacatgcc
     5701 tgtcgtacca caaaatcccg tgtctgatga ggcacgggat tttttagctt ctttactgag
     5761 atggattttc ctttttagtt cgtgccaatc tcaaggcacg atttggattg agacgattaa
     5821 atagttcttc caatttcttt tcattccaaa cgtctgcggc ggaaacaaaa ttaccatccg
     5881 catctcggaa agatatcggt ttatctccca taccagtctc ctagtctaca aattcaaact
     5941 caaatttacc aatgcggacc aaatccccat ctttagctcc acgcgcacga agggcttcat
     6001 caacccccat accacgaagc tgacgggcaa atttcatgac agattcatca cgatcaaagt
     6061 tggtcatatt aaagagtttc atgagttttt caccagaaag tacccatgtc gcatcgtcat
     6121 cacgactaat ttcaaaggct ttttcttctt cgtcaaatcc atagtaagct tcttcttcca
     6181 tatcggactc gtcgtagagc aaaaattctg gtgtcttgtc taacaattca gctgtagcat
     6241 ctaaaagtgt tgccagacct tgcttggtca atccagaaat tgggaagata gctggtaact
     6301 cttcaaattc atcataattt tcagccaatt ttttcttaaa gtcttcaaga ttttcctgac
     6361 tctcaggcat gtccatctta ttagctacaa taatctgtgg acgctccatg aggcgaagat
     6421 tgtaagactc cagctcttta ttgatagcta ggtagtcctc atatggatca cggccttcgc
     6481 tagctgacat atcaatgatg tgaaggataa cacgtgtacg ctcgatgtga cggaggaact
     6541 gagttcccaa accaacacct tgactagccc cttcaatcaa acctggcaag tcggctactg
     6601 caaaggattc acctgattgg gtgcgaacca tacctaaatt tggtacaata gtggtaaagt
     6661 ggtaggcacc aattttaggc ttagctgagg taataacact taaaagtgtt gacttcccta
     6721 cagatgggaa tcctactaaa ccgacatctg ccaagatttt tagttccaat tgtaactcac
     6781 gttcctgacc tggttctcca ttttcagaga tttccggtgc aggatttttt ggtgtcgcga
     6841 aacgaatatt tccacgtcca ccacgaccac cgtgggcaac gataaattct tgcccatgtt
     6901 caatcaaatc tgttaaaacc ttgccagtct ccgcatcacg aacagtcgta ccttgtggta
     6961 ctcgaactct aaggtcctca gcaccacgac catgcatccc tttggtcatc cctttttcac
     7021 cagaatcagc cttgaaatga cgattgtagc ggaaatccat caaggtacgt agtccttcgt
     7081 ctacaacgaa gaccacattg cctccacgac caccatcacc accccaaggg cctccattag
     7141 ggacatattt ttcacgacga aaggcaacca taccatcgcc accattacca gccttgacct
     7201 taatcttagc tgtatctaaa aacatactca ttatttcttc tcactttaaa aaagggctgg
     7261 gaaatcccag tcactaaatt ttcttgaatc tattttatag attactgagg gcaccaattg
     7321 cagttgcaaa aattcccaat aaacttgcta ctagcatgat aatcacgata aacaaggtta
     7381 ttttctcaaa catagttttt ttacgatttc cattatctcc aaatgccatt tttctctcct
     7441 tcgttacatt ctattttcta ttatcttagc atgaattgag ctagttttca atagtcagtt
     7501 gctactggtg cgataatcca taaaataatg taagctacaa ttccagctcc gtaacagcaa
     7561 gtaagaacac cccaaatgac ttgaacgata gtcggatcca tatccagata atgggccacc
     7621 ccagcacaaa cacccgcaat ctttttatca cgaccgcttc tcattaattg tttttttcat
     7681 agctgttcct ctttctattc ttcatggtct ttccaatagt ctctcatact gatcaactgt
     7741 gtttttgaag ccttcaacat gcgtctagat ccttttacag gtacagcaac cacctgttgc
     7801 tgaagataca aaactgtctt aaagatacgc tgactgaccg tatcatcttt agccaaatct
     7861 ttctggaagt tatttgaaat aatggcatcc agataaaact catgcactcg tttcccaaag
     7921 ttctcagctg aaatctcata caatttctct gataaggtat gctcgttcat gtctggtgtt
     7981 gcaatcaggg cttccaaaat agcaccagcc aaatcatgtt ctccatagta caaggttcca
     8041 aacattttat cactgatgag gttgttcaaa taaggatttc cgtgagcaat gacaggtgtt
     8101 ccactggcta agctttccaa gtaggtcaaa ccttgcgttt cgcttgtcga tgccgaaatg
     8161 aagaaatccg ccgctttata gtaaagagcc gtctcactag gagcaatcat ccctgtaaag
     8221 atgactgagt cttgaatctc taggttctgg gcttgctctt tgaggtcatt cagataaggg
     8281 ccatccccag ctactaccag tttaaccttg tcttcctctt tcagaacatc agcaaaggct
     8341 gctaaaactg cttgaatatt tttttcatag gagattctcg aaagactaag caacgtcttt
     8401 tcaccatctt gaatccctag tttactacgc agttctttca aattttcctg cttgatttcc
     8461 ggacgctcaa acttggctaa ttcaatccca gtaggaatga cccgtttttc aaccttgacc
     8521 ttataatcag atagcaagtc acggacaatc tcactagggc aaataacccc atccacatca
     8581 tgcaggaaac ctctaaccag atacttgacc atactcgacc ggatcaacat ccccttagca
     8641 atataatgga catagtcttc atactgggtg tgataggtat ggatgactgg aattttcaat
     8701 tcacgcgcaa tccaaatccc caacaggcca agagaaaatt ctgtctgagt atggataata
     8761 tctagctgat actgtttagc aatttcaagt gccttgctaa aacctcggta ggcaaagcga
     8821 cgatccttaa aagcaaagaa aggaacactt ggaatgcgga taatttgcca atcttcgtag
     8881 cgattgacat ccttatctgt cgtcgtaaag ataaaaacag catgtccctg cttttcaagt
     8941 tctgttttca aggttcgaat actggtcgca acaccagaaa cctgaggaaa ataggtatct
     9001 gtaaataaac caattcgcat agattacctc actttttact ttctccctaa agcggcttgt
     9061 ttctcataaa agtccaacca gatttgtaac agatgctctt cagaatactc tctggaaata
     9121 ttcttggcct tttctttgag atcttttaag acagcaggat ttgcttgata ttccaaaata
     9181 gcctctttca tctcttctct acccgctgtc gcccgataat ttccctccaa aatcacctta
     9241 tagagatcta aatcacgcaa cataatagga gcctcacaac tcgcagcttc taaaatagtc
     9301 ataggaaaga gctcattgta actaggcaac aagaaaagat ccgctagagc atacaattcg
     9361 cgcatccgct ctggcgatac aatgcctgga aaaatcaaat ttttaggggg attttccata
     9421 attttcttat agtgttcata accatctgtc ataccaccaa aagagaagcc accagcccag
     9481 ataaaggtaa tctgaggcaa ttcctcagcc agacggataa agtcatcaat ccctttacgt
     9541 ttctgaactt gcccagcacc tactacgata aactgattgt cactaagacc aagatctgtg
     9601 cgcagtctga ctacctcttc ttgtggtaga ggatgccatt tttccttgtt gacaaagtta
     9661 ggaatatagg tcactttttc acgtggaata ccagctgcta ccaaatcctc aataaacata
     9721 ggattgacca caaccaagtg ctccatccgg ttgtaaaaag aaaatacata gcgtttcaca
     9781 attcccttta agaaaaatgg aattttcaaa cttccttcaa gtgtagctgg caagaaatgc
     9841 acatagccaa tctttctccc tgagcgtttc ttttggaagg ttgataaata atagggaaaa
     9901 tcaatcgtat gaaagtgagt cacatctgcc tcgattggaa gattttctgt aacaatcaat
     9961 tggtccttgg cagcacggtg aagaagacga actaattcac ggtaagcacc tgaaactccc
    10021 tgtcctgcta ctttctcact tgaactcaac atattgatgc gtaatttctt tttctccata
    10081 actactatta tatcattttc tttgaataaa atcagcaaaa gaaaggagag actagaggaa
    10141 aagaggggaa atttcctcgc ttttccaaca gtctctcaca tgcttttata tgtttactta
    10201 atgcctaggg caatgcgggc atagcgactc attttttcaa ctgtccaggc tggataccag
    10261 actaatttaa cctcagtatc cgttacttct ggaacctcta tcatagcatc ataaatctgg
    10321 tctgtcaaaa ggtctgctaa gggacaaccc atagttgtca aagtcatgtc aatctctgtt
    10381 tgccctgtgt caccgtcaaa acgaatctca tagatcaaac caagattgac aatatcgatt
    10441 cccaactcag ggtcgatgac ttcttccaag gctgttaaaa tccgtgtttt gatgttttca
    10501 atttgctctt ctgtataagc catattttcc tcactcttag tcttcaataa aatcacgaag
    10561 cggtttgctg cggcttggtt ggcgtagttt tctcaaagcc tttgcttcaa tctgacggat
    10621 acgctcacga gttacgttaa agactttccc cacatcttca agtgtgcgca tttttccatc
    10681 atctagtcca aaacgtagac gcagaacatt ttcttcacgg tctgtaagag tatctaagat
    10741 ttcatccaat tgctcacgca agacgatacg agtcgtataa tccactggat tttcaattac
    10801 ttcatcttcg ataaagtctc caaggtggct atcgtcctct tcaccgatag gagtttcaag
    10861 agatactggt tcttgggcaa tcttcaagat ttcacgaacc ttatcaggtg tcatatccat
    10921 tcgttcagca atctgttctg gtgtcggatc ttgccccaat tcttgaagga gattccgctg
    10981 ttcacgaacc aatttattga tagtttcaac catgtgaact gggatacgga tggtacgagc
    11041 ttgatccgca atagcacgag tgatagcctg acgaatccac caagttgcat aagttgaaaa
    11101 cttgaaccct ttagaatagt caaacttgtc aaccgccttc atcaagccca tatttccttc
    11161 ttgaatcaag tcaaggaact gcatgccacg accgacatag cgtttggcaa tagaaacaac
    11221 caaacgaaga ttggcttccg caagacgttg tttggcttcg atatcgccag cttcaacagc
    11281 cagtgccaac tctttctcct cttcattggt caagagagga acgaccccta tttctttcaa
    11341 gtacatacgg acagggtcat tgaccttagc agaagttgac ccaatcaagt cctcatcgct
    11401 gagttctggt tcttcttcat tgctaagaac acgcgcactt ggatttcctt cgttatctgt
    11461 gatagaaatg cctgcatcct gaatccgttg caagagatct tcaatcccat cagcgtccaa
    11521 ggtaaaagga ataaccagac ttgcattgat ttcatcatct gttgctgtcc ctttttgctt
    11581 atgattacgg ataaattctg ctacctgtac gtcaaatgtt gttacttctt tttgttttgt
    11641 tgccattatt actccattct tctcttttgg gaaattaaac gttccaattc ttctagggct
    11701 gtatctgtat ctcctacatg gctagcttcc tgcaccttct ttttgattct catattgtcc
    11761 tgattcaaga gagccttgtt tcgagtcatc tctacttcac taagttcctg cggcgatatc
    11821 tcagcaggca aatcctgagc taaaacttgg taccaagctc tttcaacttc ctctgtctgc
    11881 tctgctaaaa cttctggagg aagatttcca tactggccaa gcaagtcata taagacctga
    11941 aattcaggtg tagcaaatgc aaagtcttct cgcaaacggt aatcgttcaa aacaagaggg
    12001 gattccatca tccgatagag tagatgggct tctgccctca taatagccga taactgcttg
    12061 gtgataggca tggtgattgg cgtcggtctg gaaattcctt ccatgcgatt ctgcctttgc
    12121 acctgacgac tctcattaac aatctgctca atctgggtat aatcaaagga cgccagactg
    12181 tcagctaaaa tatgaatata gctgttttga gcagcgatgg acttttcttg aacaatcaag
    12241 ggagctattt tttcaataaa ctcaatctga gcctgcagat tttcactgtt ttcaggtttg
    12301 tactgatgaa tgtagaactc aatcggacta atacgagttt ttgttaatag ataggccaag
    12361 tcttctggac catttttttg tagatactca tcaggatcca agttatcagg catgctaacg
    12421 atttgcacag gcatatcacc aatttcatcc aatgctttca atatcgcggc ttgcccagcc
    12481 ttatctccat cgtaaacaag aaccaatttc ttggttaacc ttttcagatg ctcaacatgc
    12541 tctcgactca aggccgttcc catcgacgcc acagcatttt cgattccagc ccgataggct
    12601 gcaataacat ccatgaatcc ttccatcagg taaatctcac tagcttttcc agaagatctt
    12661 tttgccctat ccatatgata taattcgtaa cttttgttaa aaattgcagt cgatcggctg
    12721 tttttatact tagaagtttg tgaatccgtt ttttgccaga tacgacctga gaaggcaatg
    12781 acctttcctt ggtcatttgt caggggaaac ataatgcgat tgtgaaaggt gtctacaaat
    12841 tgattggcat ccgagagata aaacaggcct gaatccagta aatcctcttc acgatactga
    12901 tcagacaaac gttgatagag atagtttcgt tctggaggtg ctaaaccaat ccaaaaatgt
    12961 ttaagcactt catctgtcaa accccgctga taaaggtaat ttctggcctc ttctcccata
    13021 gtcgttgtca tgagaatagc atggtaaaat ttggctgcat cttcgtgcat atcataaaga
    13081 gcttggtgag gcgaggctgg cttctgttca ctataaagcg gtttttcaac ctcaatcccg
    13141 acacgctgac ctaagatttg gacagcctcc ataaaggtaa ccccttggta ctcctcgatg
    13201 aatttaaaga catcacctga gcgaccacaa ccaaaacagt ggtaaaactg cttgtcctct
    13261 acaacgttga aagaaggtgt tttttcacca tgaaaaggac agagccctag atagttccgt
    13321 cctgcctttt gtaaagaaat cacatctcct atgacttcca caatgttggc attgtttttg
    13381 atttcttcaa tgacttgttt gtcaaccata cacaatacct ccatgttatc atagtttact
    13441 ttatatagta tactttattt cagaaaaaaa gtaaaccatt tcactcattt tccctacttt
    13501 attcaaagag ttgataataa tcagagattt tcatttttgc tttttcttct tggtttaaat
    13561 cttggataat ccgtccttct ttcatgacaa tcaagcgatt gccgtatttg agagcatctt
    13621 ccatatgatg agtaatcata agggctgtta gctgatcttt cttaacaaat tcatctgtca
    13681 attccatcaa agcaacacta gtctttggat ccagggcagc agtatgctca tctaacagga
    13741 gtaattcagg tcgcttcaag gttgccatca agagactcaa agcctgtctt tgtccacctg
    13801 ataagaactc aatcggtgta ttcaagtgtt tctcaagacc atttcctact ttttcaatgg
    13861 ttgcctgaaa ttcatcctta tagctagtca agcgtcttgg taacaatcca cgcttttcac
    13921 cacgaaactt ggcgattaaa agattttcag cgaccgtcat acggggagct gtccccatct
    13981 ttggatcttg gaagacacga gacaggtact tggcacgctt ctcgggtgaa aacttagtga
    14041 gatcttcacc taaaatacgg atagttccac tagttagtga taaggtccct gctatagtgt
    14101 taaagagagt tgattttcca gcaccatttc cgcccaaaat cgtgataaag tcccgttcaa
    14161 aaatttctaa ggaaacatca tttaaaataa tcttttcttc atcaaagcca tttttaacga
    14221 ttttggttgc attttttaat tctacaattg ctgtcatttg cttaacttgg ctcctttcaa
    14281 gattgtttgc ttaaatgttg gaatcatgag gcagactgct aaaatcaaag cactgtataa
    14341 acgaaggtaa cttgtattaa agccaagtgc gataactgcc cacactaaaa attgataagc
    14401 gatagaacct acaacgatag taaccaaacg ctctgccaag ctcaaactct tgaaaataac
    14461 ttctccaata atcaaacttg caagccccac aacgataacc ccgatccctc gagacacatc
    14521 ggcatagcct tcttgctgag caatgagggc acctgcaagg gcaatcacac catttgataa
    14581 gaccaagccc atgagatcca tgcgtccagt atgaatcccg aaacttctag ccatatcagg
    14641 attatcccct gtagcaatat aggcttgtcc gagtttagtg tccaagaaaa agagcatgag
    14701 agcaataaca atgctcacaa agatgagacc tgtcaagagt tgattcaaat ccgaatcaaa
    14761 aggcaaaaca tcctgaattt gcttggttcc aagcaggcct aaatttgcac gtcccataat
    14821 caagagcatg attgagtgac aagaagtcat caccaaaatc cctgagagca aggttgggat
    14881 cttccctttt gtataaagaa ggcctgctgc cattccagcc aaacaacctg ctcctacagc
    14941 aacaagtgtc gctaaaaatg gattcacgcc tttggttatc aaagtgacag caacagctcc
    15001 cccaagaggg aaggaacctt ctgtcgtcat atctggaaag tttaaaatcc taaatgtcat
    15061 aaagattccc agacctagaa tagcccagac aaatccttga gaaataatgg aaacaatcat
    15121 attttattta atcctttcta tattcatctt tttaaaaaat gggaagagtc tcctcctccc
    15181 taccttattt attcgatgac ttgtcctgct tctttgagaa cagactcagg aatagtaata
    15241 cctagttctt gtgctatttt tttattgata actgacttac cagttgaaaa gacattgact
    15301 ggggtatcgg ctggttttgc acctttcaag acttgcacaa tcattttacc tgttgccaca
    15361 ccaaggtcat gttggtcaat tacaactgat gccaaaccac ctacttctac catagctgtc
    15421 gcactgggat aaattggttt cttagaactt tgattgctag agacaaccgt tggaaatcct
    15481 gatgcaatgg tgttatcaat tggaacccaa atagcatcta ccttgctagt cataacagtg
    15541 acagttgagg caatttcatt tgttgaagga actgcaaatg tttccactgt cagacctgct
    15601 ttttcagcat aagccttaaa ttcttcgacc tgtgtttttg aattgtcttc gctacttgag
    15661 taaagagctc cgattgtttt cacattcggt gtcagagcct tgatgagttc aacttgttgt
    15721 tgagctggat tgtggtcaga tacccctgta acgttgccac ctggtttttt caaatcttta
    15781 accaagttag caccaattgg gtctgtaata gcggccatga taaccggtag gtcttttgtt
    15841 gcactagcca acccttgggc tgctggtgtt gcgataccaa ccacaaggtc attcccattt
    15901 gcaaccaatt gtttactcat tgtcgcaacc ttactttggt caccttctga gttcataaaa
    15961 tcaattttaa cttgatcatc tttatatcct tcttctgcaa gtccatcttg gatcccttta
    16021 taaatcaaat caagggatgg atggctcaca aattgaagca caccaatctt ggttattttc
    16081 ttctcatcct tattattctg aacttctgat ttattcattg aagaataaat caagcttcct
    16141 gctactaaga ctgctaatgc agcaataatt ccaattaaac gtttattttt cattctgttt
    16201 ctccttttta tttcctttaa catatttcac ttatctaaac aagcgacgcc attgttttct
    16261 ttccatacta acctccatca aaaaaatcct cacacaaaaa acttgtgtga ggacgtcgat
    16321 gcgcggtacc acctcaatta tagggaattt ccctatcgct cagtctcgca ataacgagat
    16381 gcactgtaag gtgtgcttac cgaattttta taatttcaaa ttctaaatag cattcagccc
    16441 aattttcatc attgccactt atctgttttc agctaccaca gactctctaa aaagtttgta
    16501 tgattacttt tctgaatggt taaattatat catttttaaa ctacttgtca atagtctatt
    16561 agaatttttt tgatattcac ttttagcatt cactcttgaa aattatcaac ctgaattacg
    16621 caatcctgtc gcaattccgt tgatggtgat atgaatcaat cgttcttgat cactggacaa
    16681 ttctccacga cgttggcgtt taatcaactc taactgaata tagttgagaa tattaaagta
    16741 aggcatacgg taatccagac tagcttttag atatggattg tcagctaaga gttcgtcatg
    16801 tccttcaata gccaagataa cgttcttagt aacttgccat tcatttaaaa tagtctcata
    16861 gatggcctta acttgctcgt cttcacaaag tttagcatat tcaaaagcaa tattcatatt
    16921 tgattttgac aaaaccatat caacatttga aagaagcgat tggaagaaag gccaattttg
    16981 gtacatatct cgtaagatag caatattctc tggattttta ttgataaatt ccttgaagct
    17041 tgaaccaacc ccgtaccatc cagggaacat aacacgactc tgtgaccatg agaataccca
    17101 agggatggca cgcaatccac cgatttcagt aatagtctta cgagcggctg gacgagaacc
    17161 aatattaaaa cttgaaatag ccttgattgg acttgaatcg aagaaataat catagaaatg
    17221 ctcattacca aagaccaaat cacggtagat atcgtaacta cggtccacta cttgatccat
    17281 aatggcttca taacgatttg gggtattggt atcgctcttc ttctgagtaa tcatacggtt
    17341 aatagctgcc gatactagca tttcaaggtt atagtaagcg gcgtctttgt taccgtattt
    17401 attcccaatt acttcaccct gctccgtcaa gcggatacga tccttgatag acttgagcgg
    17461 ttgagatgta atggcttcat aggttggccc accaccacga ccgacagtac caccacgacc
    17521 atggaagaag gtaaccttaa cgccaaattc atctccaata gcagtcaatt gttgttgagc
    17581 cttgtagagg gtccaacatg atgacaagta accgccatct ttattactgt cagagtagcc
    17641 aagcatgatt tcttggtagt tatttcgtga gtcaatccat tttttggcaa ggctaagaga
    17701 aagatatttt ctcattgttt cctctgaatg atccaagtct tcaattgttt caaaaagggg
    17761 aacaatctga acacgcgccc tttccgtatc caccagtcct acttctttta acagaatagc
    17821 taattctagc atatcagaaa ggctggttgc atgtgaaatg atggtctgac ggatgacatc
    17881 atctcccaac ttatctttca aaacacgagc cgtcttaaaa atagctaatt cttttgctaa
    17941 taattctgat ttttctgcgt gagtcgcaga aagaattcgg ggatcttctt ctaattcttt
    18001 caagagaagg tcacactttt cttcttcgct caactcgcta taacgagaat gaattcctgc
    18061 tgatttcaag agttctgcca cacaggcttc atagacgcta gagtcttgtc gcatatcaat
    18121 tgacgctaag taaaaaccaa atatctctac tgcctgcaat aattccacaa aatcacctga
    18181 aatcaaggac tcacccttat tttctagtag agaatctcga atggcaatca aatccttgta
    18241 gaaatcattg gcggtttcat aacgagtccc aacttcttca tcctcaatca gataggtttt
    18301 agttgcctga atttttgatt gaatatcaaa caaggcacga cggtaaagct ctttttcgcg
    18361 gtaaatagag ttatccttgg attgacgagc catttctctg acttgcttgc tgacgttgac
    18421 aatgctagtt gaaagagaaa attcacgata aagttggtaa atctttttat catagtagtt
    18481 catgatgact tcacactgag tgagtgcaga ctgcttcaag gtctttgctg taacaaatgg
    18541 atttccatca cggtcaccac ctatccacat acccatggtg attggtttag cctgttttaa
    18601 attcagacca tgcgcttgcg ctaagcgctt atactccgtc gtcaaatgag ggacagcttt
    18661 caaaaaggag ctgttgtaat attccatagc attcgtgatt tcgttagtca cttttaattt
    18721 tttctcacga atcatgtctg tctgcatgat aatttcgatg taacgacgca aatcattgtg
    18781 ccatttatct ttattgatta accccaactt aacatcacgg tatttacgca aaagactatg
    18841 aatatgattt gttaaatcca acatactttt gcgttgcact tgtgttggat gggctgtcaa
    18901 aacagggaca acattcaagt gttctaggat ctcaacggca ttttcctttt ctgctaccaa
    18961 tttaatcgtt gtagataatt tacctaaata gtcctgatca atattatttt gatgattgat
    19021 ttcataagct aaatccacat cctctgaaat attaatcaaa agaggtaaga tagagaaata
    19081 gcgtgaaata tagaccattt catcatttga taagctagtc actagacggt ttagaccttg
    19141 ataatcttcc tgcgttgata attctttcaa ctgtattatt ttttcaaagg tctctggggc
    19201 aagcatattt ttagtaatat cttccagtaa ttctgttaga atcaagactt cttctttcac
    19261 aacactttta ttactataat tttctaattt ttgaagagac ataaactatc ctttctttat
    19321 cctacttcaa cagaaggttc attggttgat tttccaattc tcggtacaac ttagcgcgtt
    19381 tttcactggc atcaatattt aagacaaagg ctactgccac tgataagact agaagactat
    19441 ttccaccctg ggataagaag gggaaagtca ctcctgtaga tggaatcaag cccgaaatcc
    19501 ctccgatatt gacaaatacc tgaaccaaca tcatccctcc gacaccgagt gcaaccatgg
    19561 cattgaaagg attctccgct cggataccga ccaagataat ccgcaaaatc atgaaaaaca
    19621 agagagctaa aataagactg gcaccaacaa agccaaattc ttcaatcacg atagaaaaga
    19681 caaagtctgt atgagcttct ggcaaataac ctcgtttttc aatcgagttt ccaagaccta
    19741 gaccaaacca accgccattg accatggcaa aataagaatt agctaactgg tgacctgcat
    19801 cagcacgatc ggcaaaagga ttaaaaaagg cactaaagcg cttggctaca tagccaaata
    19861 ctggaatttt tgaaaaggtc tcaacaccga ttaggctgat agtggtcaag acaaagacag
    19921 aagtggcaga tacgagcgcc agaatggttg aaaaccagcg ataagcgatt ccactaactg
    19981 tatacataat caaggaaacc aagactaaaa tagtcgcatt tcctaaatca gggaaaattc
    20041 ccaaacttcc aatcagaact aggagaacga atcgccaatc attaaaagca cggggaagcc
    20101 attgattttg agtcaaaact tgaaaatcat aagtagctat ttcttcttgc tgtttggaga
    20161 atcggtgagc taaataccaa ataataatga tttttaagta ctcagctggc tgaatagtta
    20221 ctcctgcaac cgaaatccaa ccgtatgccc cgtttacgga aataccaata aaacgagcca
    20281 agaacaataa aagcatttct attaatataa ctaaaatgat tagtcgctca tttctcaaaa
    20341 aatctagtct caatttataa attaaggcaa tcagtatcaa actaacaatc caaaagattc
    20401 cttggtttcg aaccaactgc aaggcactct tgccttcttc aattaaaata gcactggtgg
    20461 tcgaatagac cacaatcaag cccaaaatag ataaaagcaa gtagggaatc aagatggaat
    20521 aatttaataa gtgcctctta ctaatcttca tagcatcacc actctactag gatacagata
    20581 aatctgttcc aaattccgtt ttattttcta gttttgattg ctattatacc attttttcag
    20641 aaagaaaaaa actcttacct tacaatcctt cgaattttac tgtttttaca gaattaaggc
    20701 agaatttgaa atcgtaaaac cattttgaat aagagttgct tcaacccatt gactccgacg
    20761 gattaagttg ctttcgtgaa tgccaaaatc agccgcaatt tgttcataag tgctctattc
    20821 tcgcatgtat tgaatagtta ccataaggag atcgtctagg attaatttgc tttttcgtcc
    20881 accttttgcg cgtttacgtt gataagctgt ttttaacaca gctaacatct cttcaaaagt
    20941 cgtgcgctga acacctacaa ggatcttgaa acggctatcg cttaattgtt tacttgcttc
    21001 atcatccata gttttattgt attgtatttt tgtttcgcag gaagtctatt attcctttcg
    21061 ttccaaggtt tttacgcttt ttcaagcaat cctacacact ccacgtgatg cgtctgtgga
    21121 actcaaaagg ttcggggaac cttttgagga ttaattgcgt ttctctaaca aactcacaca
    21181 ttcaacgtgg catgactgat gaagtcatca taagaatttc acttgctgct ctttctcggt
    21241 ggcagcctga acggtcagaa gtatcattgt atatcatttg tatcatggca tataaagtat
    21301 cgctctattt tattgatggt tttaatatcg ctcttatcat ggcgaaccat tcaaatctgc
    21361 tccacaaatg aggaaagtac cattttggac tattcaattg tcaaagaaca aataaaaaaa
    21421 atcttcgcat tttcacactc tatgaaattg aggagattat tttctaaagc gaattttatc
    21481 aggaaaatcc gtcaatccca ataggtagtc tgtactgaca tcgtaaaagt ttgagagagt
    21541 taccaatata tctgctgtta acgtatgctc accccgttca attttagcat aagctgagtc
    21601 tgtaaacgaa agtattttag ctatttgttt ttgggtcaaa tcgtgatctt ccctcaaatc
    21661 tctcaaacgt ctgtacatct agctttctcc tgagaaaagt ataatatata aaactaagaa
    21721 atcattcaaa gtgtccaaac tggacatttt gaactaaaat taatttatta aacatatctc
    21781 ataagcatat ctattatagg taagacaata ttaagaaaga cggtcaaaat ctattaaccg
    21841 tctaaagatg ttataagcta ttaaaaaatc agcagtaatc cggtaacaaa agtcacataa
    21901 ttttgttaag gaagggatta atgatgtcca gattactact aaccagcaaa ttgaaaaatg
    21961 gtcaacatga tatttctaat gtgaatctct tactttcaga acctaaaagt tgaataatag
    22021 ccacccccta cttatcaata aaattttccg ttgcattaac agatgtatat agaccactcc
    22081 atggatttca aagcaattaa ctagacttta tttgtcaata accacaaaat tagattagaa
    22141 aaatcattaa aaattaattg gagtcctttg tgatgctttt tcaataaaag taatacttct
    22201 caatatttta actgaactaa agaaatagca taatggtatc ttgattgtat tcttctaaaa
    22261 aggattgccc ttcacattca actgtgattg attaaattcc aaaaatatat tccaaaggcg
    22321 ctctaaattc tctatatcag ctatttttta tcatctatca acttctatca tacctcttca
    22381 atagcgtgct aaatattagc gataatatcg taatagatac accaataata aaaaaattaa
    22441 aagtattgtt aggatttaaa actactgaga aaaaaacagt acctagtggc ataaaaagaa
    22501 tagctaccgt aaagatgatt ccaaatactc tgccaagaaa ctcattatct acgtctcttt
    22561 gaacaataga gaaaaattgg atattaaaaa tggaaagaaa tagactaaat aatgctggag
    22621 taaaggctaa aataatgacg ttgcggaaca tataatagat cggcgctgtt agcattaaca
    22681 tcaaacctga atatgctaaa aagagcatta aacgtttgct tgacaaggat ttattgataa
    22741 atccacttaa tatcgcacca ataaagccac caatcgcttc ggctgttaaa aaggttccat
    22801 atagcccact tgaaatactt ccaaacattt gattactgta tggcagcaac aaattatagg
    22861 ctgctaggaa aaagttaaca agtgctgaaa gggcaattat agtgagaatt tgtttatgac
    22921 tatatacata cgtaaatcct atttttaaat catcaaagat tcctcttatc gtcatattct
    22981 cttttgtatc cacctcctca tttacaggag taatgaagaa aattagtgag gcagcaatta
    23041 aaaacgataa tccatctagt aataacacac catgtattcc aagtaactta tataagaaaa
    23101 ttgcaatcat aggaattgtt actttaatca cagtacttgt tgtttctagc aatgaattaa
    23161 gttatgatat actgtccttt tttacaattt ctttcgtaaa agctttgtat gatggccctg
    23221 aaaaagcact cataaaagcc aaaatgacat ttgttatgac tatcgcataa accaaccatt
    23281 tttcttggga tataaatgaa agagttatgc aagcaatacc acataagata tttgtagtaa
    23341 taataatttt tttccgcttg aaactatctg caataactcc accaaataaa ttaaatagaa
    23401 cacctatcat actttctaat gattgataaa ttgcaaccac tgatagagat gttggattaa
    23461 gaccagcaag aaaggtatta ttggcgaaat caaacatgat atctccgatt cgagatatca
    23521 tcctactagc tacaatggat agaatattgt gatgttcttc tctaatcatt ttattctccc
    23581 gaatcagtaa tcacatattt aaacttttgt gatatgtgct taagttcatc taaccttttc
    23641 tcaaattcac aactattttt gcaattaaat tggaccaaca ttgaattttc gactacattt
    23701 tcagatactt tatagtaagt atttggttta ataaatatgt acactttttt tgcccaagcc
    23761 aattcttttt catcaggtac ctcgataacc ttaccttgct ttctatataa agcaaacgtt
    23821 gctgagatat tagcaggtct agaaatcact ttagaaaaat ttattttttt caatccttgt
    23881 gaattagtca aaatatccca atattcttta attacatcaa ctccatgact atcctcaatt
    23941 aactggggaa tatctccccc tccaaatctt tttccaactt cacaaaagac tattttacca
    24001 gttgataatt caaggaacca ttcaaaatga aaaggggtta tttcagaatt gatagaaaaa
    24061 acattcaaaa ctttgcgaca ttcttccaat gctttttcta tgtattcaat tttttcacta
    24121 tcattatata acgaactagt ccttacaaga taatatccac tagaacttaa ggtattgaac
    24181 aatagttcct catattcgtg aacataaaat cgcttaatct cacttccaat tgaataacca
    24241 tcacatgtta tcatgttatc gatatcaatg tattcctcta taatatagtt tttttcaaaa
    24301 tacactgaat caattttctc gttagggtaa acttttttta ttccattact tcctgcttca
    24361 tttctaggtt ttaaaattgc agcagaagat ttacaattat tccaaaaaac acgtaaatca
    24421 ttttctgatt ctaaaagcct aaaatacggt tgatttacta ctccaactaa aaatgaacgc
    24481 atgaagtatt tgtctttaaa taataaatta gacacagagt gagtattttt ttctacaaaa
    24541 tgatcattca aaaaacctac tatatccatg tcttcctcac tcaaggttgt aatactctca
    24601 acttctgtat tttgacttat ccttctaatt tctaagatga tatttggtag aataaaatct
    24661 tctaaaaaaa tgaccttagg tagattattt ccttcagcta gataatcttc atattttttt
    24721 ctttgaacct caggtgcaat aattactaca tttctgttat acagatattt tagtttaaca
    24781 acccgtgcag aatatctaaa taatactata tgcatgttaa tcccaatcct ttcaattatt
    24841 agtcatcata tccatttgga tgtttctgtt gccatttcca cgtatcttgg cacattttca
    24901 taatatcata ccttggcttc catcccagta gctcttctgc ttttgaaata tctgcaattg
    24961 aaacgtccat atctcctgct ctccttgaag ttatcttata tggaatatac gagcctatga
    25021 cactctctaa gctgtgtagg atttcaaata cactaaaacc aacaccactt cctaaattga
    25081 ttacttcata taaaccttca tctgtattaa aaatatactc taatgctttt ctgtgtccgt
    25141 atactaaatc gttaacgtga acatagtccc ttatacaagt cccatcagga gtactgtaat
    25201 caactccgaa tatatttaaa tatggtaatt ttccaattgc aacttgtgta atgtaaggaa
    25261 caagattatt cggaattcca tttggatcct ctcctaaatc accactttca tgtgcaccca
    25321 atggattaaa atacctcaga caaacaattt tccaatttga attcgaaata aacaaatcat
    25381 ttaaaagtac ttctatatac tgttttgttc tcccatacgg gtttgaagct tttaatggat
    25441 tagtctcata gaatggcatg ataggagtac tttcgtatac agtagctgat gaactaaaca
    25501 caaaattaaa taccttatat tttttcatta gttttaaaat atttatagtt gataataaat
    25561 t
//
LOCUS       DBJKQU010000026        23913 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.026, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000026 DBJKQU010000000
VERSION     DBJKQU010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23913
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.026"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(116..2374)
                     /locus_tag="ACSUUC_001228"
     CDS             complement(116..2374)
                     /locus_tag="ACSUUC_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHQ8054442.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2603..2833)
                     /locus_tag="ACSUUC_001229"
     CDS             complement(2603..2833)
                     /locus_tag="ACSUUC_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HHQ8054443.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3023..3706
                     /locus_tag="ACSUUC_001230"
     CDS             3023..3706
                     /locus_tag="ACSUUC_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHQ8054444.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3706..4440
                     /locus_tag="ACSUUC_001231"
     CDS             3706..4440
                     /locus_tag="ACSUUC_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054445.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQILSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4594..5451
                     /locus_tag="ACSUUC_001232"
     CDS             4594..5451
                     /locus_tag="ACSUUC_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HHQ8054446.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5593..6465
                     /locus_tag="ACSUUC_001233"
     CDS             5593..6465
                     /locus_tag="ACSUUC_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HHQ8054447.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPESMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6747..7430
                     /gene="rpiA"
                     /locus_tag="ACSUUC_001234"
     CDS             6747..7430
                     /gene="rpiA"
                     /locus_tag="ACSUUC_001234"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HHQ8054448.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFEQAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7444..8655
                     /locus_tag="ACSUUC_001235"
     CDS             7444..8655
                     /locus_tag="ACSUUC_001235"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - metabolic compound salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HHQ8054449.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEADIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8657..9199
                     /locus_tag="ACSUUC_001236"
     CDS             8657..9199
                     /locus_tag="ACSUUC_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HHQ8054450.1"
                     /translation="MTRYALLVRGINVGSKNKVVMAELHQELTNLGLEKVESYINSGN
                     IFFASIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9215..10024
                     /locus_tag="ACSUUC_001237"
     CDS             9215..10024
                     /locus_tag="ACSUUC_001237"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HHQ8054451.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKIDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10500..10895
                     /locus_tag="ACSUUC_001238"
     CDS             10500..10895
                     /locus_tag="ACSUUC_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipase family protein"
                     /protein_id="HHQ8054452.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            10905..11480
                     /locus_tag="ACSUUC_001239"
     CDS             10905..11480
                     /locus_tag="ACSUUC_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HHQ8054453.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKARFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDGSGKEIE"
     gene            11505..12017
                     /locus_tag="ACSUUC_001240"
     CDS             11505..12017
                     /locus_tag="ACSUUC_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
                     /protein_id="HHQ8054454.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12671..13381
                     /gene="deoD"
                     /locus_tag="ACSUUC_001241"
     CDS             12671..13381
                     /gene="deoD"
                     /locus_tag="ACSUUC_001241"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HHQ8054455.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13404..13928)
                     /locus_tag="ACSUUC_001242"
     CDS             complement(13404..13928)
                     /locus_tag="ACSUUC_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HHQ8054456.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13981..14217)
                     /gene="rpsT"
                     /locus_tag="ACSUUC_001243"
     CDS             complement(13981..14217)
                     /gene="rpsT"
                     /locus_tag="ACSUUC_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HHQ8054457.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            complement(14285..15205)
                     /gene="coaA"
                     /locus_tag="ACSUUC_001244"
     CDS             complement(14285..15205)
                     /gene="coaA"
                     /locus_tag="ACSUUC_001244"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HHQ8054458.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15395..15798
                     /locus_tag="ACSUUC_001245"
                     /pseudo
     CDS             15395..15798
                     /locus_tag="ACSUUC_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16005..16595
                     /locus_tag="ACSUUC_001246"
     CDS             16005..16595
                     /locus_tag="ACSUUC_001246"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHQ8054459.1"
                     /translation="MSKMYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDF
                     GSQLLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEK
                     NNAKATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16592..17869
                     /locus_tag="ACSUUC_001247"
     CDS             16592..17869
                     /locus_tag="ACSUUC_001247"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HHQ8054460.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17887..18549
                     /gene="deoC"
                     /locus_tag="ACSUUC_001248"
     CDS             17887..18549
                     /gene="deoC"
                     /locus_tag="ACSUUC_001248"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HHQ8054461.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18536..18925
                     /locus_tag="ACSUUC_001249"
     CDS             18536..18925
                     /locus_tag="ACSUUC_001249"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HHQ8054462.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19016..20068
                     /locus_tag="ACSUUC_001250"
     CDS             19016..20068
                     /locus_tag="ACSUUC_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family lipoprotein"
                     /protein_id="HHQ8054463.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20212..21747
                     /locus_tag="ACSUUC_001251"
     CDS             20212..21747
                     /locus_tag="ACSUUC_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054464.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            21740..22798
                     /locus_tag="ACSUUC_001252"
     CDS             21740..22798
                     /locus_tag="ACSUUC_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8054465.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22801..23757
                     /locus_tag="ACSUUC_001253"
     CDS             22801..23757
                     /locus_tag="ACSUUC_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8054466.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            23842..>23913
                     /locus_tag="ACSUUC_001254"
     CDS             23842..>23913
                     /locus_tag="ACSUUC_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HHQ8054467.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKL"
BASE COUNT         6960 a         4323 c         5444 g         7186 t
ORIGIN      
        1 agattcagtc tactatatat cataatggac aaagggcaag ctgtcaagaa attacagtta
       61 ttttagtaaa aaaagaagca gaaaaatttc attttctact ccttttctat aggatttatt
      121 tttctttttc agaactttta acttcagctt ttttggcaga tttaatctga atgtttccct
      181 tgctagtcat aactgctttg agatcttttt cgcttggatt ttcaaggtag tagtcagtga
      241 ttgtgtcctc aatatagtct tgaatagtcc gacgaagtgg gcgtgctccc atttttggat
      301 cataacctag gtcaaccaac ttttccttga ccttatcagt tacatccaaa cgaatgttgt
      361 tgctagagag gcgcttgtta acatctgcta gcatgagctc gacaatctga aggaggttat
      421 ccttgctgag agccttaaat tcgataatgc catcaaaacg gttcataaac tctgggctaa
      481 agaagttacc gagttcaccg aggacagaat tggtacgtcc ttctctagca gcaccaaatc
      541 caacgctagc ttcggtcttt cctgtacctg catttgaggt catgataatg atggcatcct
      601 tgaagctaac ggtgcgtcct tgcccgtctg tcaaacgacc atcgtccaag acttgaagaa
      661 acatgtgcat aacatctggg tgagcttttt ccacttcatc gagaaggatg agagaatatg
      721 gattgtggcg aactttttca gttaattgac cagcctcatc atagccaaca taacctggag
      781 gggcgccgac caacttagcc acactatgtt tttccatgta ttcactcata tcaaagcgaa
      841 tcatactatc agcagaacca aaaagttcga tagccagttg tttggaaagt tctgtcttac
      901 cgacaccagt tggcccaacg aagaggaagc ttccgattgg gcggttaggg gtaccaagtc
      961 cgacacgatt acggcgaata gccttggcaa tcttatcgac tgcatcatct tggccaataa
     1021 catgagactt gagatcttcg gctagatgga tgagttgaga ttgttctttc tctttcaaat
     1081 caccaacagg gatattggtt ttctgctcga taatgtgctc aatagttttc tcgctgatga
     1141 taggagtatc ctggtctgtg atctttttct tttgcatttc cttatacttg gcaatctggt
     1201 cgcggaagta ggccgccttc tcaaaatctt cttctcgtgt agcttgagac ttgagatttt
     1261 cagcctcaat caagcgctga tcaattactt taggatccac aaaattcaag gtcaagttca
     1321 tcttagaacc agcttcatct aggaggtcaa tggccttgtc aggcaagaag cgatcttgga
     1381 tgtagcgatt ggaaagagtt gcagctgctt caatcgcagc atctgtatat tgaacgtggt
     1441 ggtaatcttc gtatttcttt tgaatccctt tgagaatagt gattgtttcg tccaccgttg
     1501 gttcatcgac tttaacaggc tgcatacgac gctcgagggc agcatccttt tcaatgatac
     1561 ggtattcatt gagggtagta gcaccgacta gttgcagttc tccacgagca agggctggct
     1621 tgaggatatt tcctgcgtcc atattaccat cactcgcaga accagcacca acaatttcat
     1681 ggatttcatc gataaagagg atgatgtctt cacgtttgcg aatttcttcc atgagttttt
     1741 gcatgcgttc ttcaaattgt cctcgaatcc ccgttccttg aactaagcta accacatcca
     1801 gacggatgac ttgtttacct tggagtttat gtggcacatc gccatcgaca attttctgag
     1861 ctagaccttc gacaacggcc gtttttccga caccaggttc accgataagg acaggattat
     1921 tcttggttct acgattgaga atctcgatga cacggataat ctcatcgtcg cgcccaataa
     1981 cggggtcaat gtctccacga cgggcaattt cagttacatt aataccaaat tcttccagca
     2041 ggcctttttc ttggctaggt ggcggagttt gagcagatcc acgattttgg gaaccataac
     2101 cgccgtttcc accgtaacct ccacctgatt gggttggggg aataggagga gtattgctag
     2161 aaggtctgaa attgtttaga tcattgaaga aatcaccaaa gggatcgaag tcacgattgt
     2221 tcagatccgt catacctttg aagaggctat tgttaggatc tgttttgata atcttatagc
     2281 agttttgaca gaggtcaatt tgtttttgtt ttccattgag attggtgtaa agatgaattg
     2341 ttgagtcgtt aattttacag ttttgacaaa gcatacatct acctcatttc tttctttagc
     2401 ctgacttgtt taaaggtcaa aaatagtcaa attctatact ctcattataa caggattggg
     2461 gtgtaaagca agtaaaaaga ttgaagcttt gagaagttgt tacaatgaaa atttttgtga
     2521 atttggacta taaaaaaatc ctatttgtga gacaaaaagg attttactta gacatgcagg
     2581 gacaatccca gcttgtttta gattagtaga gaagttcgta aatttccatt gcgattaagt
     2641 caatgctatc aaacgtatac gtttcgcgat cttctacgtc acgaagggta aagattgggc
     2701 cgttttcttc gtcgtggctg tacgcaactt ctgcaacaac aactccttcg cgttcaaaat
     2761 tacgttttaa atttccgcca tcgtttgcca ttgcttcaag gcggttgatg attctaacca
     2821 aatgtgattc cattttgatt ctccttcatt tcttatcgtt actattttac cataaaggag
     2881 gccaacttga ctagaaaaaa ctaagatttc tcgctaattc tgctagttta aagattttta
     2941 aataaattgg ataaaaaatt taaattttaa ttcaaaacat gttataatca tacagtattc
     3001 tattttagaa agcagtgtga ctatgaattt ttctttttta cctaagtatt taccttattt
     3061 taactatggg gctgttgtga cgattcttat ttctatctgt gttatctttt tgggaactat
     3121 tttgggtgtt gtcttggctt ttgggcaacg ttcaaagttt aaaccgcttg tttggttggc
     3181 caacttgtac gtttggattt tccgtgggac accgatgatg gttcaaatta tgattgcctt
     3241 tgctcttatg catatcaatg ctccgactat tcagattgga attttaggtg ttgatttttc
     3301 gcgtctgatt ccagggattt tgattatctc tatgaatagt ggtgcttatg tttcggagac
     3361 tgttcgtgcc ggaatcaatg cggttccaaa aggtcagcta gaggcggctt attcgctagg
     3421 gattcgtcct aaaaatgcga tgcgttatgt gattttgcca caagcagtca aaaatatctt
     3481 gccagcattg gggaacgaat ttatcaccat tatcaaggac agctccctct tatcagctat
     3541 tggggtcatg gagttgtgga atggggctac aacagtttct acaacaacct atctaccttt
     3601 aacaccactt ttatttgcag cattttacta cttgattatg acctctattc tgacagtagc
     3661 cttgaaagct tttgaaaaac atatgggaca aggagataag aaataatgac agaaaccttg
     3721 ataaaaattg aaaatttaca taaatctttt ggaaagaatg aagtattgaa gggcatcaac
     3781 ctcgagatta aaagaggaga agttgtcgtt atcatcggtc cttcagggag tgggaaatct
     3841 accttgcttc gctctatgaa tttgttggag gaagcaacca aggggaagct tatctttgag
     3901 ggagtcgata ttacggacaa gaagaatgac ctgtttgcca tgcgtgagaa gatgggcatg
     3961 gttttccaac aatttaacct ctttcctaat atgactgtga tggaaaatat taccttgtca
     4021 cctatcaaga ctaaaggtga aagcagggaa gttgctgaga agagagccca agagcttttg
     4081 gaaaaagttg gtttgccaga taaggcagac gcttatccac agattctgtc gggtgggcaa
     4141 caacaacgga ttgccatcgc gcgtgggttg gctatggaac cagatgtttt gctctttgac
     4201 gaaccaactt cagccttgga tcctgaaatg gtaggtgagg tattggctgt tatgcaagac
     4261 cttgccaagt cagggatgac tatggttatc gtaacacatg agatgggatt tgcccgtgag
     4321 gtggcagatc gtgttatctt tatggcagac ggtgtggttg ttgaagatgg gacacctgag
     4381 cagatttttg aacaaaccca agaacaacgg actaaagatt tcttgagtaa ggttttataa
     4441 tctattttaa aatttcaaga caagattagt gaaaagttca accagagctt tttcttatag
     4501 tttgaaacta taggataacc taggaaagaa gtgttagagg gcactagcag tttttggtat
     4561 aatggaagat atttgaaaga aaagagaagt gatatgacac agattattga tgggaaagct
     4621 ttagcggcca aattgcaggg gcagttggct gaaaagactg caaaattaaa ggaggaaaca
     4681 gctctagtgc ctggtttggt agtgattttg gttggggata atccagccag ccaagtctac
     4741 gttcgcaaca aggagaggtc agctcttgcg gctggttccc gtagcgaagt agtgcgagtt
     4801 ccagagacta ttactcaaga ggaattgtta gacctgattg ctaaatataa tcaggatcca
     4861 gcttggcatg ggattttggt ccagttgcca ttaccaaaac atatcgatga agaggcggtt
     4921 ttattagcca ttgacccaga aaaggatgtg gatggtttcc atcccctaaa catgggacgt
     4981 ctttggtctg gacatccagt catgattccc tcgacacctg caggaattat ggaaatgttt
     5041 catgaatatg ggattgactt ggaaggtaaa aatgcggtcg taatcggtcg ttcaaatatc
     5101 gttggaaaac ctatggctca gcttcttttg gctaaaaatg cgacagtaac cttggcccac
     5161 tcacgaactc ataatcttgc caaggtggct gctaaagcag atattcttgt agtcgcaatc
     5221 ggccgcgcca agtttgtgac tgctgacttt gtcaaaccag gtgcggttgt cattgacgtt
     5281 gggatgaatc gagatgaaaa tgggaagctc tgtggagatg ttgattatga ggcagttgca
     5341 ccacttgcta gccatatcac gccagtccct ggaggtgtcg gtcctatgac cattaccatg
     5401 ctgatggagc aaacttatca agcagcactt cggacattgg atagaaaata agagaaacat
     5461 tcgattaata gagtgtattt tctatagcta tatctaaaat ggcagaaatg aatattaaat
     5521 tttagatata agattacaaa aggaggtctg cgtctccttt ttattgtata ataaaagtga
     5581 gaggaaaaaa ggatgaaagt gattaatcaa accttattag aaaaagttat tattgaacgt
     5641 tctcgttcaa gtcataaagg agattatggt cgtctgctgc tgcttggtgg tacttatcct
     5701 tatggaggtg ccatcatcat ggctgcttta gcagctgtaa aaagcggtgc aggattggtg
     5761 accgttggaa cggacaggga aaatatcccg gctctgcaca gccatttacc tgagtctatg
     5821 gccttttctc ttcaagacca gcaattgtta aaagagcaat tggagaaggc agaagttgtc
     5881 ttgctggggc ctggtttacg agacgatgct tctggagaaa atctagtaaa acaggtcttt
     5941 gttaatttaa gccaaaatca gattttgatt gtagacggag gtgccttgac cattcttgct
     6001 aggacaagtt tgtcatttcc ctcaagccag cttatcctaa ctcctcacca aaaagaatgg
     6061 gaaaaattat ctggaattac gattgaaaag caaaaggaag atgcaacggc tagtgttctg
     6121 acttccttcc ctcaaggaac aattttggtg gagaaaggcc cagctactcg tatttgggaa
     6181 gttggccaat ctgattatta ccagttacag gttggtggtc cttatcaggc gactggggga
     6241 atgggagata ctctggctgg gatgatcgca ggatttgtag gccaattccg acaggccagt
     6301 ctctacgagc gtgtggcagt agcgacccat cttcattcag ccatagccca agaactatct
     6361 caagaaaatt atgtggtctt accgacggaa atcagcaggt atcttcccaa aataatgaaa
     6421 attatttgtc aacaagagag ggtaagcaaa gataaacttg tttaaaatag acagataaat
     6481 ctacttcctt ctcttaattt atgattcttg aaatgcgcct gctttaaggc taaactagac
     6541 gtatcaaagt taagagtttg tttttgtaac tggaaagaga tgaacaaatc aaatacataa
     6601 aagataaact catttttatt cgtttggtaa aaataaaatg catattttta aagaaagatt
     6661 gatgaaaaat gtagatttga tgtttttact tgaataaaaa gcggtttcat agtaaaataa
     6721 gaattgagaa tgatggaggt aaatcggtgg aaaatctgaa gaaaatggca ggtatcaagg
     6781 ctgctgagtt cgtgagcgat ggaatggtcg ttggacttgg aacaggctcg actgcctatt
     6841 attttgtcga agaaatcggt cgtcgtatca aggaagaagg attgcagatt acagctgtaa
     6901 caacttctag tgtgaccact aaacaggcag aaggccttaa tatcccgctc aagtctattg
     6961 accaagtaga ctttgtcgat gtgacggttg atggcgcaga tgaagtggat agtcagttta
     7021 atggaatcaa aggcggtggt ggtgcccttc tcatggaaaa ggtggtcgca acaccatcaa
     7081 aagaatacat ttgggtggtg gatgaaagca agctggtcga aaaactaggt gcttttaaat
     7141 tgccagtaga agtggttcag tatggtgcag agcaggtctt tcgtcatttt gaacaagctg
     7201 gctacaaacc aagtttccgt gaaaaagacg gccaacgttt tgtgacggat atgcagaatt
     7261 ttatcattga cctcgccttg gatgtcattg aaaatccaat tgcttttgga caagaattgg
     7321 accatgtcgt tggtgttgtg gagcatggtt tattcaacca aatggtggat aaggtaatcg
     7381 ttgctggacg agatggagtt cagatttcaa cttcaaaaaa aggaaaatag aagggggcat
     7441 aagatgtcta aatttaatcg tattcatttg gtggtactgg attctgtagg aatcggtgca
     7501 gcaccagatg ctaataactt tgtcaatgca ggggttccag atggagcttc tgacacactg
     7561 ggacacattt caaaaacagt tggtttgaat gtcccaaaca tggctaaaat aggtcttgga
     7621 aatattcctc gtgaaactcc tcttaagact gtagcagctg aaatcaatcc aactggatat
     7681 gcaacaaaat tagaggaagt atctcttggt aaggatacta tgactggaca ctgggaaatc
     7741 atgggactca acattactga gcctttcgat actttctgga acggattccc agaagaaatc
     7801 ctgacaaaaa ttgaagaatt ctcaggacgc aaggttattc gtgaagccaa caaaccttat
     7861 tcaggaacgg ctgttatcga tgattttgga ccacgtcaga tggaaactgg agagttgatt
     7921 atctatactt cagctgaccc tgttttgcag attgctgccc acgaagacat tattcctttg
     7981 gatgaattgt accgtatctg tgaatacgct cgttcgatta cccttgagcg tcctgccctt
     8041 cttggtcgca tcattgctcg cccttatgta ggtgaaccag gtaacttcac tcgtacggca
     8101 aaccgtcgtg acttggctgt atctccattt tccccaactg ttttggataa attgaatgag
     8161 gctgatatcg atacttatgc tgtgggtaaa atcaacgata tctttaacgg tgctggtatc
     8221 aaccatgaca tgggtcacaa caagtcaaat agtcatggaa ttgatacact attgaagact
     8281 atgggacttg ctgagtttga aaaaggattc tcattcacaa acctagttga ctttgatgcc
     8341 ctttacggcc atcgtcgtaa tgctcacggt taccgtgatt gcttgcatga gtttgatgaa
     8401 cgcttacctg aaattatcgc agctatgaga gagaatgacc ttctcttgat tactgcggac
     8461 catggaaatg acccaacgta tgcaggaacg gatcacactc gggaatatat tccattgttg
     8521 gcctatagcc ctgcctttaa aggaaatggt ctcattccag taggacattt tgcagatatt
     8581 tcagcgactg ttgccgataa ctttggtgtg gaaactgcta tgattgggga aagtttctta
     8641 gataaattgg tataagatga cgcgctatgc tttgctggtg agaggtatca atgttggtag
     8701 taagaataag gtcgtcatgg cggagcttca tcaagaattg acaaacttgg gactggaaaa
     8761 ggttgagagc tacatcaaca gtggcaatat tttctttgct tcgatagatt ccaaagccca
     8821 attggttgaa aagctagaga ctttctttgc agtccattat ccatttattc agagcttttc
     8881 tttactgagt ctagaggact ttgaggcgga acttgaaaat ctaccagctt ggtggagcag
     8941 agacttggca cgaaaagatt ttctctttta cactgagggt ttggatgtgg accaagtcat
     9001 cgcgacagtt gaaagtttag agctgaaaga tgaagtgctt tattttggaa aacttgggat
     9061 tttctggggg aaattttctg aagaatccta ttctaagact gcctatcaga agtatttgct
     9121 gaaggtgcct ttctaccgcc acattactat tcgtaatgct aaaacctttg acaaaattgg
     9181 tcaaatgcta aaaaaataat aaaggagaca cacaatgaca tttttaaaca aaatccatga
     9241 aactgctact ttcctgaaag aaaagggaat tgcagcccct gagttcggtc taatccttgg
     9301 gtcaggactt ggagaattgg cagaagaaat cgaaaatcca gttgtagtag actatgctga
     9361 gattccaaac tggggccgtt caacagtagt cggtcatgct ggtaaattgg tatatggtga
     9421 actggcaggt cgcaaggtct tggctcttca agggcgtttc catttctatg aagggaatcc
     9481 tctggaagtg gtgactttcc cagttcgtgt gatgaaagtt cttggatgtg aaggtgttat
     9541 tgtaaccaat gcagctggcg gtatcagatt tggtcctggt accttgatgg ctatctcaga
     9601 ccatatcaac atgacggggc aaaatccatt gatgggggaa aacttggatg actttggccc
     9661 acgtttccca gatatgtcta gggcctacac accagaatac cgtgccactg cccatgaagt
     9721 ggctaaaaaa cttaatatca agattgatga aggtgtctat atcggagtta ctggtccgac
     9781 ttatgaaaca ccagcagaaa ttcgttccta taagacactg ggagcagatg cagttggtat
     9841 gtctacggtt cctgaagtta tcgtggcagc ccactctggc ttgaaagttc tgggaatttc
     9901 atgtatcact aactttgcgg ctggtttcca agaagaactc aatcacgaag aagttgtaga
     9961 agtgactgaa cgtgttaaag gtgatttcaa aggcttgctt aaagcgattc ttgctgaatt
    10021 gtaagaaaaa agatttaaaa gggggagtgc ctctgtcttt tcaggattga ctgcctatcc
    10081 gtattaaaga agaaacagag gaatactatg agcttcttcc tgctcttata actgaaagaa
    10141 gcggaagaat aggtgtgtct gatctgatag ccagcattgt gaaagacaag attctaggat
    10201 actagcatta gcttcctagc caagcagact agtatgataa ggagagatga gaatgaattg
    10261 actttctgaa tttctcagtc ttatcatata tagcacaatg agatttcgct tgagtctgct
    10321 tgtaaataaa cgaaaagaaa gataagaaat aatgaaaatt ggtcaacgaa ttatgcgctt
    10381 tggcataaaa aattaagtat cggagttgta tctgttgtag tcggctttga tttctagctc
    10441 cagctggaat ttcagccaat gaagtaaagc aagatgtaac atctgaagtg gtaataggtg
    10501 tgctagattc taaggaggaa ttgaaagagt cagaaaatga tgctccaaaa ctagaaactc
    10561 ctcttagaga ggagccaaga ctagctcctc aaacgcttcc ggaagcaagt gaagttcttg
    10621 aaaacaaaag ggaagagtca aaagtagaga taacagagcc agctcaagcg gatgatatcc
    10681 gcaaggttgt tggggaatta gccaaggata taagtattac taagttgtat atgacaggtc
    10741 attctcttgg aggctaccta gctcagattg cagcggttga agattaccaa aaatatcctg
    10801 atttttataa ccatgtattg aggaaagtga caactttcag tgctcctaaa gtgattactt
    10861 ccagaactgt ttgggatgct aagaatggtt tctgagatgt tggtttggaa agtcgtaaat
    10921 tagctgttag tggaaaaatt aagcattatg tggttgataa tgacaatgtt gtgactccct
    10981 tgattcataa taatcgtgat attgttacat ttacaggtaa ttcacgcttt aaacaccgtt
    11041 ctcgtggcta ttttgaaagt ccaatgaatg atattcctaa ctttaatatt ggtaaacaag
    11101 ctaccttgga taaacatggt tatcgtgatc cgaaattgga taaagcgcga ttctttaaga
    11161 aacaggctct acctcaatct tctagtcaac caagcgctga accaatggaa aatattgcct
    11221 taggaaaaca ggttactcaa agttcgacag ctttcggagg agatgctaga agagctgtgg
    11281 atggcaaagt cgatggtaac tatggtcaca attctgtcac tcatacaaac ttccaatcta
    11341 agccttggtg gcaagtagat ttggctaaag aagaaaccat tcgccaaatc aatatttaca
    11401 accgaacaga cactgcccag gatagattgg caaactttga tgtcattctt ttagacggtt
    11461 ctggtaaaga aattgagtga aaacgtataa tatctcctaa agatgtgtca gcacaaatta
    11521 cgattaacca taaaaaagcg cgctatgttc ggattgagct agaaggctat aatgccctca
    11581 gtcttgcaga agttgaagtt ttccgcttta tagctacgaa tggtgaaacg gcgatacaag
    11641 tttctaagtc agttcaacca atcagtcaga ctcctgtgaa agataaaaca ttgacaattc
    11701 aacacagtgg agcttacatt gcccgctact ccataacttg ggaagaagtt acagtagata
    11761 aagatggaaa ccaagttgtt cgtagtcatt cttgggaagg aaacggtcgc aaccagactg
    11821 caggttttgt cctcaacctc ccaatcaaag aaaatatgag aaatctgcga gttaagattg
    11881 agaaaaagac gggcctacta tggaatagat ggcaaacaat ctatgaaaac agaccaattt
    11941 tagctcaacc ccaccgtaaa attacccatt ggggtacgac attgaattcc aaggtgagtg
    12001 acgatgatgt cttgtaatct gatggtacaa tgacagttag tttgtctagt ttataagaaa
    12061 gtactacctg agcttgaata gaactcaggt agctctctgt gaaagaacaa aattaatact
    12121 caatgaaaat caaagagcaa actaagaaac tagccgcagg ttgctcaaag cactgctttg
    12181 aggttgtaga taagactgac gaagtcagtc acatatataa tccaaggcga cgttgacgtg
    12241 gtttgaagag attttcgaag agtataaaca gaaaggtaga gcgcgtgttc taatttgaac
    12301 acgagtagaa aacttttcta aaaacaaaaa cgaaaggatg ggtaaactgt attcgctgaa
    12361 ctgaatacgg gcgactctcc tctaaatcaa aattaagaaa ggaattgacc ccaccctaaa
    12421 agtagtggga aaaagatagt tggtctagcg agcatcgctc actgcgccca actcctattt
    12481 tcccttcgct ttttgatggg tttggtatct ttctcaatat aaaatataaa ataaagaaag
    12541 gtagagcgtg tgttttgatt tgaacacgag cggaaaactc ggaaaataga taatctgact
    12601 gaaaaatcag gatttctcgt caggttccta attttcagtc gttttcttct cgctctttgt
    12661 atcataaatt atgtctatcc atattgctgc tcagcagggt gaaattgctg ataaaattct
    12721 tcttcctggg gatcctcttc gtgctaagtt tattgcggag aatttccttg gtgatgctgt
    12781 ttgttttaac gaagtgcgta acatgtttgg ttacactggt acttacaagg gtcaccgtgt
    12841 atctgtcatg ggaactggga tgggaatgcc atctatttcg atttatgcgc gtgagttaat
    12901 cgtagactac ggtgtgaaga aattgattcg tgtgggaact gcaggttctt tgaatgaaga
    12961 ggttcatgtt cgtgaattag ttttggcgca ggcggctgca accaactcaa acatcgttcg
    13021 taatgactgg ccacagtacg attttccaca aattgctagc tttgatttgc ttgataaagc
    13081 ctaccatatc gccaaagaac ttggtatgac tactcacgtt gggaacgttt tgtcatctga
    13141 tgtcttttac tcaaattact ttgaaaagaa tatcgagctt ggtaaatggg gagtcaaggc
    13201 tgtggaaatg gaagcagcag ctctttacta tcttgctgcc caataccatg ttgatgcgct
    13261 agctatcatg accatctctg atagcttggt caatccagac gaagacacaa ctgcagaaga
    13321 acgtcaaaat accttcactg atatgatgaa ggttggtttg gaaaccttga ttgcagaata
    13381 attatagcca aaaaggaagc cctttatgaa ttgtaggact tccttttctt atccagaaat
    13441 tgatctagct ctctctgatt tcgaagaata gtgactttat gtgaatattc ttggcaaagt
    13501 ttttggtaat tttctttttg agttttgcta cgcccatccc aaagaatcca tctgataaac
    13561 tcccagtcaa agcgttcagg gcaatctgcc gccatacttt ctctgacttt tccacggtat
    13621 ttaagataac gcttaaaggc tctaaagaga caggtcaatg gcaaaaaatt gagaaagatg
    13681 atttggtcag cttcttgcat tcgttcttgg tagtagcacc aagaataatt accatcgatg
    13741 acccaagctt tatgcttggt gagaaagttt tttatctcgg ttaacatcca ttcgcagtca
    13801 ctgtcttgcc aaccaggttg aaattggagt gtgtccatgt gcagttttgg aatggagtag
    13861 tagttagata acttttctgc tagagttgac ttaccagaac cagaatatcc gataattgtg
    13921 attttcattt tctacctttt cctatttgga gacaaaaaaa cagcctctat ggactgtttc
    13981 ttatttagca agtttagttg aaagacgagc tttatcgcgg cttgctttgt ttttgtgaat
    14041 caaaccttta gtttctgctt tatcgatagc tgagctagca gcacggaaaa gttcttcaga
    14101 tgggtttgct tcgaaagctt ttatagcagt acgcatagct gatttttgag ctgagttctt
    14161 ttcgttttgt ttaacgttca attcagcgcg tttgatagct gatttaatgt ttgccaatgt
    14221 tcttacctcc atatttacta actataccat tatatatgaa aacttacgtt ttgacaaggg
    14281 aaaattactt ttttaagtaa atttcatcga tttcatggtt cttgctttta tgaagaatca
    14341 cttctgcacg atttctggtt ggttcaatat aattttgcag atttgtgaga ttgatactga
    14401 tccagacctg atgggcaaag gactccactt ccccaatcgg catctgagta aaacgataat
    14461 agtagctatc agggtcgttt tgggctaggc tcagcatctt caagaaacgg tccagatacc
    14521 aactttcaat atcatccact ccagcatcta catagatgga aaagtcaaag aagtcagtga
    14581 tatagagacg atcgttttgt ggattttgaa agacattaat tccctcaaca attacaaaat
    14641 cagcagcttt gacactttgt ttcttttcgg gtacgatgtc gtaaacttca tgagaataga
    14701 caggaatatc tacatcttgt ccatttttga tgcggtccaa gaagttgaga agagcttcca
    14761 tatcatagct ttcaggaaat cctttacgat ttaaaatccc ctgctcaatc aaggtttgat
    14821 tgggatagag aaaaccatca gttgtaacca actcaaccgt agcatctgta aacgtacggg
    14881 acagtaggat ttgaagtagg cgactggttg tggattttcc aacggcaaca ctcccagaaa
    14941 ccccaataat aaaaggttga gatttacttt cacgttggag gaaaattcct tttgaaaagg
    15001 ctaaatcttc cttagttcgc ttgtaaatct gaatcagatg agccaagggg agatagatat
    15061 ctgtaacgtc ttggagactg atttggtcat taaaactctt gatagattcc aattcttctt
    15121 ctgtcaaagg aggtgttgtc tttcgatgta aagattgcca agtctggcgg ctgatttttt
    15181 caaaatgtaa aaattcgttg gtcatttgtt ttcccctaga tattttgtct atcataccat
    15241 aaaaagctaa aaaaataaag cggtttcttg aatgtggtaa gtcaatggta tatagtataa
    15301 gtgatcaatt tattgatgaa ataggagata gattctactg atttataagc ttataaaggg
    15361 ggctttttag ttcacaactt ataggaggtg tactatgaaa atcttaaaac gttacatatt
    15421 ggaactctgt tttattttaa gttttgcttt accttttata aaaggaacca atgcagataa
    15481 tggtagatgc tttgtggaaa cctattacgg ttttactttt ttgatggaac atgctattgt
    15541 aacagctgtc tttatctgtt cgttcttaat tgctttctta ctaaaaaacg atggacgaaa
    15601 tggattgctg cgggtagtta ttgcttttta gtcctacgga ttgcgacaga gggttatttc
    15661 ttccacatgt cactagaaga tttgatacga ctttggacaa gtttggaaat cctgacacaa
    15721 acgtatcagt tgggctttta tctaaacatt ttgttaggaa ttttgttgat aataaagtat
    15781 tttaaggtta agcaatagaa ataataatct gcctgattat agatgataaa ctttttgttt
    15841 ttatctggac tgtgatattt atagttctaa atggtttatt atttataagt gttgaaagag
    15901 attgaagaaa atggcttcgt gacttgcttt cttcggtctt tttcgtttta ttatcaattt
    15961 gtaaacgatt tacaatttga gtcaaattat ggtaaaatag tgtcatgagt aaaatgtact
    16021 atgcagaaaa tcctgacgct gctcacgaca ttcatgagtt gagagtggac ttgttgggag
    16081 aaaaaatgac ttttttgaca gatgcgggtg tttttagcaa gaaaatggtt gactttggaa
    16141 gtcaactctt gctcaagtgt ctggatgtca accaaggaga gacagtccta gatgtaggct
    16201 gtggttatgg tccattaggt ttgtccttgg tcaaggttta cggagttcag gcgaccatgg
    16261 ttgatattaa cactcgtgcc ctggatttag ctcagagaaa tgctgaaaaa aataatgcaa
    16321 aagcgacgat atttcaatct aatatttatg caagagttca agggcgattt gaccatgtca
    16381 tttccaatcc tcctatccgt gcgggcaagc aagtcgttca tgaaatcatc gagaaaagta
    16441 aagatttctt ggaaattggt ggagatttga ccatcgtcat ccagaaaaaa caaggagctc
    16501 caagtgccaa atctaagatg gaagatgtgt ttggcaattg tgaaatcctt aaaaaagaca
    16561 agggatacta tatccttaga agtgtgaaag aatgagagca gttgatttaa tccaaaaaaa
    16621 acgagacggt caagaactga cttcaagtga aattgaatgg ctgatagaag gctatgtatc
    16681 aggaactgtt cctgattatc agatgtctgc ctttgctatg gctgtttatt ttaaaggaat
    16741 gacgactcga gaaatctctg atttaacgat gaatatggtt aagactgggc aagagtttga
    16801 cctgtcagcc attgatggtg tgaaagttga caagcattct actggtggtg tcggcgataa
    16861 ggtaaccttg attttagctc ctcttgttgc tagcttcggt gtgcctgtag caaaaatgag
    16921 tggtcgtggt cttggccata caggcggaac aattgataaa ttggagtcca ttaggggcta
    16981 tcaagtagaa cgtagtcaag aggattttat tcgtcaggtt caggatattg gagtatctgt
    17041 cattgggcaa tcagaccagc tggtcaaagc agataagctt ctctatgccc ttcgtgatgt
    17101 gaccgcaact gtcgacacga ttcctttgat tgcgagttcg gtgatgagca agaaaattgc
    17161 ggcaggggcg gatgctattt tgctagacgt gactgtcggt gagggtgcct tcatgaagac
    17221 ggttgatgag gcgcgtgagt tggctcaaac tatggtagat cttggtaagg ttgttggacg
    17281 gaagacagta gcagtgatta cggatatgag ccagcctttg ggacgagcga ttggaaatcg
    17341 tctggaaatc cttgaagcat tggagatttt gcaaggtcaa ggacgtcagg atattaccca
    17401 ctttatttgt gaattggctc aaattatgct tggtttggca aatgttaaca aaactgttga
    17461 agaagttcgc caacatcttg aaaatggtca agcactggct aagtttgagg aaatggtgca
    17521 agcccaaggt ggagacttgg aagacctcta tcgtcctgta aatgtagctc atgtggtgga
    17581 aatccctgct caggaaacgg gtgtcatttc agctcttcca gctatggact ttggtcttta
    17641 tgccatgagg ctgggtgctg gtcgtgcagt taagtctgat gtcttggact atgaaacagg
    17701 aattgttttt gaaaagaaga ttggagactc cgttcaaaag ggtgaaattg ttgcaaaagt
    17761 atacacaaat gaaaaaattc cacctcaact agttacagat ttccaaaaat gtgttaaaat
    17821 aagtgatgaa gtgaaaaaaa tccgtgaaat tgtagaaatc atctcctaaa tggagggaaa
    17881 accgaaatga aattaaataa atatatagat catacgcttt taaaacaaga tgcaaagaaa
    17941 aaacaaattg atagtttgtt gtctgaggct agagagtatg gctttgccag tgtttgcgtt
    18001 aatccgacct gggttgaaca tgctaaaaaa ggacttgaag gcacagatgt taaggtttgc
    18061 acagtagtag gtttcccctt gggagcaaca acttcaactg tgaaagcttt tgaaacaaaa
    18121 gaagctatcc aaaatggggc tgatgagatt gacatggtaa tcaatgttgg ggctctcaag
    18181 tcaggtgatt tggccttggt tgagtcggat attcgtgcag tagtggaagc aagtggggac
    18241 aagttagtga aagttattat tgaagcttgc cttctgacag accaagaaaa agttttggct
    18301 tgccaattag cccaaaaagc aggagctgac tttgtcaaaa catctactgg cttttcaact
    18361 ggtggtgcta cgatagcaga tgttagatta atgcgtgaaa cagttggacc tgatatgggt
    18421 gtcaaggccg ccggtggagc tcgttcttat gcagatgctc ttacctttgt cgaagcaggt
    18481 gcgacccgta tcggaacgtc agctggggta gctattttaa aaggagaatt ggcagatggc
    18541 gactactgag ttgattgaac tggcaattga aaccagcaaa catgcctatg tcccctattc
    18601 tcactttcct atcggagcag ttttagtagc caaagacgga agtgtttaca cgggagtgaa
    18661 tatcgaaaat gctagctatc ctttgaccaa ttgcggtgag agaacagcta tttttaaggc
    18721 tatatctgaa ggccaaagag aattttcaga attgattgtc tatggtcaaa ctgaaaaacc
    18781 gatttcacca tgtggtgctt gtcgccaagt aatggtcgaa ttttttgaac aagatttaaa
    18841 agtgacccta gtcgcaaaag ataaatcgac ggtcgagatg acggtcgggg agttacttcc
    18901 atactctttt acagacttaa attagtctga gtcgctcttt gagtggcaag ggtctttgtg
    18961 accaatcaat ccatacttgc aacatcgttg cacatcttat ttaggaggtt cagtaatgaa
    19021 caagaaacaa tggctaggtc ttggcctagt tgcagtggca gcagttggac ttgctgcatg
    19081 tggtaaccgc tcttctcgta acgcagcttc atcttctgat gtgaagacaa aagcagcaat
    19141 cgtcactgat actggtggtg ttgatgacaa atcattcaac caatcagctt gggaaggttt
    19201 gcaagactgg ggtaaagaac acaatctttc aaaagataac ggtttcactt acttccaatc
    19261 aacaagtgaa gctgactacg ctaacaactt gcaacaagcg gctggaagtt acaacctaat
    19321 ctttggtgtt ggttttgccc ttcacaatgc agttgaagaa gcagctaaag aacacactga
    19381 cttgaactat gtcttgattg atgatgtgat taaagaccaa aaaaatgttg cgagcgtaac
    19441 tttcgctgat aatgagtcag gttaccttgc aggtgtggct gcagcaaaaa caactaagac
    19501 aaaacaagtt ggttttgtag gtggtatcga atctgaagtt atctctcgtt ttgaggcagg
    19561 attcaaggct ggtgttgcgt cagtagaccc atctatcaaa gtacaagttg actacgctgg
    19621 ttcatttggt gatgcggcta aaggtaaaac aattgcagcc gcacaatacg cagccggtgc
    19681 agatattgtt taccaagtag ctggtggtac aggtgcaggt gtctttgcag aggcaaaatc
    19741 tctcaacgaa agccgtcctg aaaatgaaaa agtttgggtt atcggtgttg accgtgacca
    19801 agaagcagaa ggtaaataca cttctaaaga tggcaaagaa tcaaactttg ttcttgtatc
    19861 tactttgaaa caagttggta caactgtaaa agatatttct aacaaggcag aaaaaggaga
    19921 attccctggc ggtcaagtga tcgtttactc attgaaggat aaaggggttg acttggcagt
    19981 aacaaacctt tcagaagaag gtaaaaaagc tgtcgaagat gcaaaagcta aaatccttga
    20041 tggaagcgta aaagttcctg aaaaataatg gatggaagtc atttcttagg aagcggccaa
    20101 gggccgcttt tttaagagtt gagacaaagt cattttgtct cagtaaagct tgctactaga
    20161 caaactagca agttttattg aaataaaata agactctgaa aggaagagca catggcacac
    20221 gaaaatgtca ttgagatgcg tgatattacc aaggtgtttg gtggatttgt tgccaacgac
    20281 aaaatcaact tgcacctacg aaaaggtgaa attcatgcac ttttaggaga aaatggggct
    20341 ggtaagtcca cgctaatgaa catgttagca ggccttcttg aaccaaccag tggtgaaatc
    20401 gcggtcaacg gtcaagttgt caatctcgac tccccatcta aagcagctag cttgggaatc
    20461 gggatggttc accagcactt tatgttggtt gaagccttca cagtggctga aaacatcatt
    20521 ttaggtagtg aattgactaa aaatggtgtg ctagatatcg ctggagctag caaagaaatc
    20581 aaggctcttt ctgaacgtta tggcttagct gttgaccctt ctgccaaggt agcagatatc
    20641 tcagttggag cccaacaacg tgtagaaatt ttaaaaacac tttatcgggg ggctgatatc
    20701 cttatctttg acgaaccaac ggctgttttg actccatcag aaattgatga gttgatggct
    20761 attatgaaaa atcttgtcaa agaaggaaaa tcaattatct tgattaccca caaattggat
    20821 gaaattcgcg cagtttctga ccgtgttaca gttatccgtc gtgggaaatc aattgaaacc
    20881 gttgaaattg caggggctac caatgctgat ttggcggaaa tgatggtagg acgttctgtt
    20941 tcctttaaaa cagagaagca agcctctaaa ccaaaagaag tggttttgtc tatcaaagat
    21001 ttggtggtca atgaaaaccg tggtgttcca gctgttaaaa atctgtcctt ggatgttcgt
    21061 gctggagaga ttgttggtat tgcggggatt gatggaaatg gtcagtctga actgattcaa
    21121 gccattacag gtcttcgtaa ggttgaatct ggtagcattg agctaaaagg agattcaatt
    21181 gtaggcttgc acccacgtca gattacagaa ctaagtgttg ggcacgttcc agaagaccgt
    21241 caccgtgatg gcttgatttt ggaaatgatg atatctgaaa atattgccct tcaaacctac
    21301 tataaagaac cacatagtaa aaatggaatt ttgaattatt caaatattac ttcttatgct
    21361 aaaaagctga tggaagagtt tgatgttcgc gctgccagtg aattagttcc tgcagctgca
    21421 ctctcaggag gaaatcaaca aaaagcaatt attgctcgtg aaattgatcg agatcctgat
    21481 ctccttatcg ttagccagcc aactcgtggg ttggatgtcg gtgccattga gtatatccac
    21541 aaacgcttga ttgaagagcg tgataatggc aaggctgtcc ttgttgtcag ctttgaattg
    21601 gatgagattt taaacgtctc agaccgtatt gccgttatcc acgatggtaa gattcaaggt
    21661 attgtatcac cagaaacaac caataaacaa ggacttggtg tcttgatggc tggtggaaac
    21721 ttgggaaagg agaagagtga tgtctaaaaa attacaacaa atttcggttc ccttgatttc
    21781 tgtattccta ggaattttac tcggagccat tgtcatgtgg atcttcggtt atgatgctat
    21841 ttggggctac gaagaattgt tctatacagc ctttggcagt ctgcgtggga ttggagaaat
    21901 cttccgtgct atgggtcctc tggtcttgat tggtcttggt tttgcggttg ccagtcgagc
    21961 tggtttcttt aacgtcggac ttcctggtca ggctttggca ggttggattc tcagtggttg
    22021 gtttgccctg tcgcatccag atatgccccg tcccttgatg attctagcaa ccatcgtgat
    22081 tgccttgatt gctggtggga ttgtcggagc gattccaggt attcttaggg cctatctagg
    22141 gacgtcagag gttattgtaa ccatcatgat gaactacatt gtcttgtatg tagggaatgc
    22201 ctttatccat gctttcccta aagacttcat gcaaagtaca gattcgacca ttcgtgttgg
    22261 ggctaatgca acctatcaga caccttggtt agctgagttg actggtaact cacggatgaa
    22321 tattggtatt ttctttgcca tcattgccgt tgcagttatt tggttcatgc tcaagaaaac
    22381 aactcttggt tttgaaatcc gtgcagttgg tcttaatcca catgcttcag aatatgctgg
    22441 tatttctgcc aagcggacta ttatcctatc tatgattatt tcaggtgcct tggcaggtct
    22501 tggtggagct gttgaaggtt tgggaacctt ccagaacgtc tatgttcaag gttcgtcatt
    22561 agctatcgga tttaacggaa tggcggttag tttgcttgcg gccaactcac caattggtat
    22621 actctttgca gccttcctat ttggcgttct ccaagttggg gctcctggta tgaatgcggc
    22681 gcaggtacca tctgagcttg tcagcattgt aacagcgtct attatcttct ttgtcagtgt
    22741 tcattacctt atcgaacgct ttgtcaaacc gaaaaaacaa gttaaaggag gtaagtaaag
    22801 atgtctatta taaccttgct ccccctcttg gtgtcttcta tgctgattta ctcagcacct
    22861 ctcatcttta caagtatcgg tggtgttttc tctgaacgtg gtggtgtggt aaacgttggc
    22921 cttgaaggaa ttatggttat gggtgccttt tctggagttg tctttaacct tgaatttgca
    22981 gaacaatttg gagcagcaac tccatggcta tccttgcttg tagcaggatt ggttggtagt
    23041 gttttctcta tcatccacgc agcagcgacg gttcatttcc gtgcagacca tgttgtcagc
    23101 ggtacggtat tgaacttgat ggcgcctgcc ttggctgttt tcttagttaa agttctttat
    23161 aacaaaggac aaaccgacaa cctaagtcaa acttttggac gctttgattt cccagtcttg
    23221 gcaaatatcc cagtgattgg tgatatcttc ttcaagtcaa ctagtctact tggttatctg
    23281 gcgattgcct tctcattcct tgcttggttt attctcttta agactcaatt tggtcttcgt
    23341 ctccgctctg tcggtgaaca tcctcaagca gcggatacct tgggaatcaa cgtctacaag
    23401 atgagatatt taggggttat tatttcaggt tttctaggtg gaattggcgg agcgatttat
    23461 gcgcaatcaa tctcagttaa cttctcagtg acaactattg ttggacctgg atttatcgcc
    23521 cttgctgcga tgatctttgg gaaatggaat ccaatcggtg ctatgctttc tagtctcttc
    23581 tttggacttt cacaaagttt ggctgttatc ggttctcaat tgccgttcct acaaggagtg
    23641 ccagcggttt atcttcaaat tgcaccttat gttttgacaa ttcttgtctt agcagccttc
    23701 tttggaaaag cagtcgcacc aaaagcagat ggtatcaact acatcaaatc aaaataagca
    23761 tacaaaaaaa cgtcagtcca atgactgaac tgccccccaa aagttagaca gaaaaaatct
    23821 aacttttggg gtgtttttat tatgaaatta acttatgatg ataaagttca gatctatgaa
    23881 cttagaaaac aaggatatag cttagagaag ctt
//
LOCUS       DBJKQU010000027        23662 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.027, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000027 DBJKQU010000000
VERSION     DBJKQU010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.027"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(1..619)
                     /locus_tag="ACSUUC_001255"
                     /pseudo
     CDS             complement(1..619)
                     /locus_tag="ACSUUC_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(728..1246)
                     /locus_tag="ACSUUC_001256"
     CDS             complement(728..1246)
                     /locus_tag="ACSUUC_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HHQ8054468.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1283..1411)
                     /locus_tag="ACSUUC_001257"
                     /pseudo
     CDS             complement(1283..1411)
                     /locus_tag="ACSUUC_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(1473..2342)
                     /gene="rsmI"
                     /locus_tag="ACSUUC_001258"
     CDS             complement(1473..2342)
                     /gene="rsmI"
                     /locus_tag="ACSUUC_001258"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HHQ8054469.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETSLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2345..2662)
                     /gene="yabA"
                     /locus_tag="ACSUUC_001259"
     CDS             complement(2345..2662)
                     /gene="yabA"
                     /locus_tag="ACSUUC_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HHQ8054470.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2702..3592)
                     /locus_tag="ACSUUC_001260"
     CDS             complement(2702..3592)
                     /locus_tag="ACSUUC_001260"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HHQ8054471.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3589..4227)
                     /gene="tmk"
                     /locus_tag="ACSUUC_001261"
     CDS             complement(3589..4227)
                     /gene="tmk"
                     /locus_tag="ACSUUC_001261"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - dTMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HHQ8054472.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4447..5244)
                     /gene="proC"
                     /locus_tag="ACSUUC_001262"
     CDS             complement(4447..5244)
                     /gene="proC"
                     /locus_tag="ACSUUC_001262"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HHQ8054473.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLSRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5248..6510)
                     /locus_tag="ACSUUC_001263"
     CDS             complement(5248..6510)
                     /locus_tag="ACSUUC_001263"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HHQ8054474.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADDDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(6520..7629)
                     /gene="proB"
                     /locus_tag="ACSUUC_001264"
     CDS             complement(6520..7629)
                     /gene="proB"
                     /locus_tag="ACSUUC_001264"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HHQ8054475.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7730..9625)
                     /gene="cbpE"
                     /locus_tag="ACSUUC_001265"
                     /gene_synonym="pce"
     CDS             complement(7730..9625)
                     /gene="cbpE"
                     /locus_tag="ACSUUC_001265"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HHQ8054476.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREEIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSSSPIGSYDSGQEINREYISWLESMGIQYINAASKDYDATVFDIRQDGLVNISTSYK
                     PIPSFQAGWHKSSYGNWWYQAPDSTGEYVVGWNEIKGEWYYFNQTGILLQNQWKKWNN
                     HWFYLTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQY
                     MGQWYYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWH
                     KKANDWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVS
                     IEKSATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSV
                     NKSESEQ"
     gene            complement(9628..10515)
                     /locus_tag="ACSUUC_001266"
     CDS             complement(9628..10515)
                     /locus_tag="ACSUUC_001266"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HHQ8054477.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10505..10966)
                     /gene="lspA"
                     /locus_tag="ACSUUC_001267"
     CDS             complement(10505..10966)
                     /gene="lspA"
                     /locus_tag="ACSUUC_001267"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HHQ8054478.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRASQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10963..11871)
                     /locus_tag="ACSUUC_001268"
     CDS             complement(10963..11871)
                     /locus_tag="ACSUUC_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHQ8054479.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLARKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11864..12061
                     /locus_tag="ACSUUC_001269"
     CDS             11864..12061
                     /locus_tag="ACSUUC_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHQ8054480.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12112..12783)
                     /locus_tag="ACSUUC_001270"
     CDS             complement(12112..12783)
                     /locus_tag="ACSUUC_001270"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHQ8054481.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLMESGVLLLAVIYLLVFAGKKTFHFKWQLRYFIYLLLGYITSYMSDFLFSYFISLSS
                     NQISLNETIEMIGRQELPYFLLIVCFIGPIAEELIYRGVLMTTFFKNSPWYGDVLLFA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNIYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12837..13058)
                     /locus_tag="ACSUUC_001271"
     CDS             complement(12837..13058)
                     /locus_tag="ACSUUC_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HHQ8054482.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWKMEPVLTLL
                     VHGFCPRDTDDLGYIGGGNHLCKGSAARF"
     gene            13330..14139
                     /locus_tag="ACSUUC_001272"
     CDS             13330..14139
                     /locus_tag="ACSUUC_001272"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHQ8054483.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14320..15195)
                     /gene="aguB"
                     /locus_tag="ACSUUC_001273"
     CDS             complement(14320..15195)
                     /gene="aguB"
                     /locus_tag="ACSUUC_001273"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HHQ8054484.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15205..16290)
                     /gene="aguA"
                     /locus_tag="ACSUUC_001274"
     CDS             complement(15205..16290)
                     /gene="aguA"
                     /locus_tag="ACSUUC_001274"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HHQ8054485.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16287..17414)
                     /gene="nspC"
                     /locus_tag="ACSUUC_001275"
     CDS             complement(16287..17414)
                     /gene="nspC"
                     /locus_tag="ACSUUC_001275"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HHQ8054486.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGSRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17414..18673)
                     /locus_tag="ACSUUC_001276"
     CDS             complement(17414..18673)
                     /locus_tag="ACSUUC_001276"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0009085 - lysine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HHQ8054487.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(18670..19530)
                     /gene="speE"
                     /locus_tag="ACSUUC_001277"
     CDS             complement(18670..19530)
                     /gene="speE"
                     /locus_tag="ACSUUC_001277"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HHQ8054488.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            19786..20911
                     /locus_tag="ACSUUC_001278"
                     /pseudo
     CDS             19786..20911
                     /locus_tag="ACSUUC_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857010.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(21029..22504)
                     /locus_tag="ACSUUC_001279"
     CDS             complement(21029..22504)
                     /locus_tag="ACSUUC_001279"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HHQ8054489.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINTIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            23239..23662
                     /locus_tag="ACSUUC_001280"
                     /pseudo
     CDS             23239..23662
                     /locus_tag="ACSUUC_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         6939 a         5398 c         4236 g         7089 t
ORIGIN      
        1 tgtaattctc aagctgtgag ttcattatga tttgtaaatc cgatatatct tcagcagcta
       61 aaaacacatt ttgaaatgtt ccaagtccgt tttcaccaaa actatattct ctcttactat
      121 acttactctt attattctct atatagttag agtcaaggtt cttaacctct tgaagttcat
      181 tttctttact tctgaggtta aaatctttta cttctgaagt taagtttttt gacttctgta
      241 agtcattttc ttttacctga aatatactca taaagtcttt aacataaatg atgttcggct
      301 taccaagtcc aagccttact ctttcgatca gtcctattcc tttttttaca tcaagctcat
      361 ctaatgtttt tatggcagtt ggctttgaga tatttcttct tttcataatt tcttcgacag
      421 taaaatagat aaatactctg ccttccttgt ctatccagtt attcttaaat gacattcctg
      481 tctatttaag aagtatggaa taaaggataa ttgcttctgc tgataagccc cgaaattctt
      541 ctctatcaac taatatctcc ggtactttta agaagttaaa tcttttcgct tctctgttat
      601 aaaaatattc aaagtccatg caagatcacc tcccttctta aaaatttgca aagaaaaaga
      661 cgatagtttt tcttctatcg cctttggtaa ccatttttat gaaatttttt aaagttaaaa
      721 atataattta taatactatc ttcttccatt ttctgatttt agttctgaaa gttccaaaag
      781 gtgcaaccgt atttacatga ataaacttat acacttccca agtcgctgtt ttagtcgctt
      841 catcagccca ctttctcata tgcggttcaa ataattcttc ctcactcaac gaatcaatca
      901 ttgcagagat agaatgaata ttttcattta attttgcttt caactcttgc agagataaat
      961 gagcgtaggt atctgtgaac cactgatata attcaccaag ttgattccat ttaaatttat
     1021 ccgatggtgt ttttacttga agcccctttc tttcatcttc ttcccattta agaaccaagt
     1081 tggtccaacc aacctgataa gcaaggtttt ctgctggagt tctgtcaact tcatcagctc
     1141 tcttatcttt taaattttct ggaatattat caaattctaa aatatatttc tcaaatgttt
     1201 tctctatctc agcttttagt tcttctttat tttcgtatgt tcgcaaaaaa tcaccttctt
     1261 tctgatttat caatcctttg atttaaaatg accttatttt tctatttata ccttctaaga
     1321 acgctataac tgctgctcca accatcggta ttccgtatgg gcttaataaa aaacttaata
     1381 ccaaagcttc tataccaagt gatacatctt tatattatca tcactaatta agttaaacag
     1441 aaacagacag aattattaca tcctgtctcc ctttattgtt tttcttccca gtcgtggtag
     1501 gcagcgtaga gttgactctt attccactgg taaatcttag cgacttcctt aatagcttga
     1561 tttttcttca taccttgctg gatacgagct tggatttcta agaacaagtc ttcctcgtct
     1621 ttttcttcca catcctgact ggcaccttca acaatcagaa gacattcacc cttgagagac
     1681 gtttcagcaa tgctttccag caattcagaa attgtacctc tttggtattc ttcatagatt
     1741 ttggtcaatt ccctgaccaa gacaacggag cggtcaccgt agacttctag catattttcc
     1801 aatgtatctg ccacacgatg gggcgattca taaaaaatct gagtttcagg atagtctttt
     1861 ttcgagtcga aaaattgctt ttgctggcct gattttctcg gtaaaaagcc gtaaaagata
     1921 tgtggctgcg gcgctaaacc actggcaatc aaggcggaaa ttcctgcaga ggcacctgga
     1981 actgtaacaa ctgcaatttc ttcctcaata gctgccttaa ccaaatcatg accagggtct
     2041 gaaatgctag gcaaaccggc atcagagacc tgagcaatac tttgccctgc tttcaagaaa
     2101 ccaatcaaat caggaatttt ttccttggca ttgtgctcat gaaaactgat ctgcttggtg
     2161 gaaatgtcaa aatgcttgag caaaagacct gtattgcgcg tatcctcagc agcaatccag
     2221 tccacttctt tcaaggtctg gatagcacga aaagtcatat catctagatt gccaatcggc
     2281 gttgccacta gatacagctt gccataggga gactgcccct taaaactttt ttgaatttgc
     2341 atgcctactc cctgtataac aactcatcac agaacataca ttcttcgtcc tgctctcgac
     2401 gttgtccata aaaatcatta catacgtgaa atccatcacg gtaaatgcga cggacacttt
     2461 cacgaacatg cttggccttg acaggagcat ctgcttccac ctcacccaag cgttctcgca
     2521 acttagaatt ttccaaacga agagctgtat tttcctctac caggctcttg agatttttct
     2581 tgatggcttc cacatcggcc aaggttacca ataactgttg ggaaaaatca tccagcgcgt
     2641 caaataattc ttttttgtcc ataaaacagc cctttccttt ctttatcatt catttttgag
     2701 tttatatttc tttcaagacc agatattcca tggcattttg aaagctgaca ttagcttgcc
     2761 acatttttct agcttctagt aaatcttgta gaatcactct tactcttacc tgcaagaggt
     2821 cctgcccaca gagaacttca agaatccgta aaacctgatc ctgtttttcc ttatcatctg
     2881 ccaagttggc taatttggca acctgtagat aactttcttt tttcttagct actaaccaag
     2941 tcagcaggcg ttcactttca tcgaccaagg tccaaaaact tgcctgatta gccaactttt
     3001 ctgcttcagc tcgcgattga ctaaacttag ctaaaagagt cgcttttttc ttaacaagtc
     3061 ccatttgttc taagagtaag ataagttttt cttcttgctt tttaaagtgg aagatctgag
     3121 tccgacttcg gattgtcggt aacatctttt cctcatcgct agtcaagaag aaaatataaa
     3181 cttcactctg gggttcttcg atgaccttga gcagagaatt ggctgcgttg ggatgcattt
     3241 tatccgcttg ctcgatgata aagacctgtt gctggctttc aatccctgct tgagaaaact
     3301 gtcccaccaa ttcccgaatg cgttctgtct tgatgacctg attgactggc ttaatcaagg
     3361 tgacatctgg aaactcttcc tgttcaatca gcttgcaact tcggcatttc tcacatggta
     3421 agacgccaac tttatccgta caaaagaggc tcttagctaa aaattgcgct atttccaagc
     3481 ttccaaagaa acctgaaaag agataggcgt gattgagctg gtcttgttct aagatacgga
     3541 caaaacggtc aaactgagct ggttgccaag cctttagttg atcttgtttc atttggccaa
     3601 gcccattccg tcaaacaaga cagccttggt agtttccaca acttgctcca aagggagact
     3661 agcatcaatc ttgacaatgc gatttccctc tttatccaga agagaaaggt agccttgacg
     3721 aactttttta tgcaagtcca acccttccaa atccaaacga ttaacctcgc ggtcactatt
     3781 agcagcaata cgagccagcc cttcttccac ctcgatgtca aaatagagtg tcaaatcggg
     3841 tttgaggcca tctgtcgcaa actgattgag ccagtcaatg gcttcaatat ctaagccacg
     3901 accaaatccc tgataggcaa cagaactatc gataaaacga tccatgatga ccaacttgcc
     3961 agcttcaagg gctggaagaa ctttttccac caaatgctgt ctgcgactgg caatatagag
     4021 aagtagctct gttttagcat ccatctgagt atgacttgga tccaaaatca cttcccgaat
     4081 cttctcccca atcaagactc cgccaggttc acgggtcgtc aacacctcta ctcctttttc
     4141 ctctaaaatt ggtagcagag cctctaaaac actggtcttg cctgctccct ctggtccctc
     4201 aagagagact aaaaatcctt ttgacatgtc taactcattt cttttttact acttctattc
     4261 tatcaaaaaa ataggggttt gtgacaatct ttttgtcttc tcatttcata ctcaatgaaa
     4321 atcaaagagc aaactaggaa gctagccgca ggctgtactt gagtacggca aggtgaagct
     4381 gacgcagttt gaatttgatt ttcgaagagt atcagccacc ataaaagagg cagataaaac
     4441 tacctcttat ttacctagtt cttgtgttcg tttataggct tgatgaactg cctccatgac
     4501 tgtgcctcga aaagcatgcg cttctaggct tgctacgcca gcaatagtcg aaccgcctgg
     4561 actacaaact tgatctttca aaactccagg atgttgctgg ctttctagga ccaattgccc
     4621 agctcctacc acagtttggg ctgccatttt caaggctgtt tctcgtgata atcccgtctg
     4681 aacacctgca tctgccaagg cttcaataaa gagatagaca aaggctggtc cacagcctgc
     4741 aagacctgtc gctgcattga ttaagctttc tcctaattca accaagagac cagccttgga
     4801 taaaagctga caaaagagct cactgtcctc agccctgcaa ttaggagaca aggcataact
     4861 aatcactcct tgcccgatag aagcaggggt attaggcatc atacgaataa ttcggtgttg
     4921 acttgggata agacttgcta gtttttctaa ggtcaatcca gctgccatcg aaatcaaaag
     4981 aagactttct cttttttcaa ggatggtctg gtattgagaa agcagttcag aaaactgagc
     5041 aggcttaact cctagaaaaa tcacatctgc ttctgcaaac atttcttcat tgctggaagc
     5101 ctgaccacca aagtctgcaa tgaaagcatc taccttagct tgactacgat tggcaaggag
     5161 aatctcatct gacgtcctag tctgcaagac agattttgcc aagctagcac ccatattccc
     5221 caaaccgata aatccaatct tcatctctta ctcccttatc tgcccatcac cagcaaccac
     5281 atacttgtag ctggtcaact ctttcaagcc cattggacca cgcgcgtgca atttctgagt
     5341 agaaatcccc atttcacaac caagaccaaa ttgtcctcca tctgtgaaac gagttgaggc
     5401 attaacatac accgctgcag agtccacttg atctgtaaag tatgctgcag cttcagcatt
     5461 ttccgtcaca atagcatccg aatgatgggt gctgtgggat tcaatgtgcg caaccgcttc
     5521 ttctaaactg ctcacaacct taacagcaag gacatagtct aaaaactcgg tgtcaaagtc
     5581 ttgggtctca gctgcttgac ctgaaacaaa ctggcttgct ttgctatcca agcggaattg
     5641 aattggttcc aacccagctt cttttcgatc tgcaaccagc acttgctcca agcgaggaag
     5701 gaagcttgct gccttgtctt catgaaccag cagaacctcc atggcattgc agacagaagg
     5761 acgactggtt ttggcattgt tgatgataga cagtgccttg tcgtcatctg cgtccttatc
     5821 gacataaaca tggacaatcc cagttcctgt ctcgataaca ggcacaatgg cattctcaac
     5881 cactgcattg atcaagccag ctcctccacg aggaatgaga aggtctagat agcccttggc
     5941 cttcatcata gcataactac tttcacggct agtatcctcc accagttgaa tcacatttgg
     6001 atgaatagta gtcgtctcca agcccttctt caaggctgtg acaatggcat gggttgtttg
     6061 ataggcatcc ttaccactac gaagaacaac cgcatttcca ctcttaagag tcaaagcagc
     6121 cgcatcagac gtcacatttg gacggctttc atagataata ccgatgacac ccatagctac
     6181 acgttttttt gtgataacca aaccattttc aagctgactt gtttctaaaa cttcaccgat
     6241 tggatctggt aaggcaacca cttcacgaat tcctcttgcc atcgcttcta tacgatctgc
     6301 atccaaataa agacgatcca acatcacatc tgagattttc cccttagccg ctgccatatc
     6361 gagggcatta gccgctaaaa tttcctcagt agcagccact aagtgatcag ccatggctag
     6421 caaggcttgg tttttcactt cttcactagc tgtgttaatc gattttttaa cagcctgtac
     6481 ctgttcaaat tgttcttgtc tactcaccat agtttacctc taaaattctg taaaaagtag
     6541 ttggatttca ggagtaatgg aaatccagtc gtcacggtaa atcaagacac ccttggcttt
     6601 ttgagaacgc aacatatcct ccaaagcaga tgctccaaat tgcacgcgtc cttttccaag
     6661 tgattttcca ctttccttat caaatactgt cacgatatca ccgtaagaaa agactccttc
     6721 tgcttcaacg ataccagata agagaagact ctttccatgt tgagagagag cttccgcagc
     6781 ccctttatca acccaaatag aaccttgact ctgagcatag aaggcaagcc attgtttctg
     6841 ggtacgaagc cccttctctt gagcaacaaa gtaagaacca tcctcggtct cctctgccgc
     6901 ctcaatcatg gaatctgatt tcaaggatga gcagatataa acaggaactc ctgattccgt
     6961 cgcgatagtt gcagccttga ttttggttaa cataccccca gttccgtttg acgaaccagc
     7021 tccaccagcc atatcaataa tctcacgatt gatggtctcg attctctcca agcgtttggc
     7081 tcttggatct gaattaggat ttccagtata gagaccgtcc acatctgtca agaaaactaa
     7141 aaggtctgct tggaccatcg ccgctacttg agcacttaga gtgtcattgt ccccaacctt
     7201 aagctcatca ataacgacac tatcattctc attgatgata ggaattgccc cacggttgag
     7261 caaaaccgac aaagcctgat gggcattttt ataacgacgc ttatccacaa agtcatcttg
     7321 ggtcagcaag atttgtgcag aaacgatttg acgcaagaga agattggtcg tatattcttc
     7381 caacaaaagt ccctgcccta ccgctgctga agcctgttta tcagcaattt tagtcggacg
     7441 ctttttaaat cctaaggctc caaaaccagc cgcaatggca cctgaagaca ccaaaatcaa
     7501 ctcatgacca gcctcgtgca gcatagccaa ctgctgggta atatccttta ccttactacg
     7561 tgataaactt ccatcctcat ttgtcagaga agaagtaccc accttaaaga caatccgttt
     7621 gtatttcata gtctcactcc gattattcat atttatccat tataacatga ataacaggaa
     7681 atagaaaaga gttgatagga aaaagaaggc cctaaaacct tcttttctac tactgttctg
     7741 attccgattt gtttacactc gtttcagagc tttgtgaagt tgaggatgtc aaatcttgac
     7801 tagttgaaaa atttgtaaca ctttcatgtt gactcgtttc tttattttca agatcctttt
     7861 tcactacttc tttggattct tttatttctg aatgacttgt agttttaatt gtagcagatt
     7921 tctcgatcga aacatccact aaccaggcac cacttgaatc cacagtataa ccttctggtg
     7981 tcttaccgtt cacaagtaat tgaccatttt ctttcaagaa gtaccattta tccttgtcct
     8041 tgatccaacc cacagctcgt gaaccgtctg tcttgtagaa ataccaatca tttgcctttt
     8101 tatgccagcc ttgcttcata gctcctgaat cttccagata ataatgttga ccagcaactt
     8161 ctatctcacc tgtcttcatg acaccagtag aatccatata gtaccaggtt tctttatctt
     8221 ttacccagcc cattttcatt tcccctgatg gagcaaagta ataccattgc cccatatatt
     8281 gaagccatcc tgtcttcata gaaccatcaa catccaaata ataccactgc tctttatctt
     8341 gaacccaacc aatttccatc tgattttctt tgttaaaata ataccagatt ccatcaattt
     8401 tcttccaatt tttagcagaa gcaccagagt ctgtcaaata gaaccaatga ttgttccatt
     8461 ttttccattg attctgtaat aagatacccg tttggttaaa gtaataccat tcacccttaa
     8521 tttcattcca accgacaaca tactctcctg tagaatcagg cgcttgatac caccagtttc
     8581 catatgaact cttatgccaa ccagcttgaa aacttggaat cggcttgtag gaagttgaaa
     8641 tgtttactaa accgtcttgt cgaatatcaa aaactgttgc atcatagtct ttgctggctg
     8701 catttatata ttgaattccc attgattcaa gccaactaat atattcccta tttatttctt
     8761 gaccgctatc atacgaacca attggtgagg aggaagtttg aacaatcaaa ctcggactca
     8821 aatttttaat gaaatccttg gtatttgatt tgttggtatc atggtgatga ttaaacttca
     8881 tcaaatcaac ttttccaatg agaggaccat acttgtcttc tgctccatga acattatcta
     8941 agtcgccccc aaggtaaatt ttcttgccat tgacttttac cacactaatc aaggaattgg
     9001 aattatcatc ccaaattttc tttaattcac ctgatgaatc ggtttcattt tcatagttat
     9061 agagttgaat atccatgtcc ccaaactgaa aatgagcatc cccttgtgtg atattttgaa
     9121 taactgaaac acctttttct gaagcagtct gtaaaacctt atcataaccg tacagattat
     9181 cccatagacg ttcagaatta gtaatacgat tatcactata tttcttaaga tagactcggt
     9241 caactggata ggtagacagt aattcatcaa catttccaat atgatcactg tgggtatggg
     9301 tcaccaaaat aaaatcaagt ttttggacac ccaattcctt caaacgacga aagacacggt
     9361 ctgttagaac atgcttataa gacgtttcaa tttcttctct ccatggatag cgagaatcac
     9421 ttccatctgg gaaatcataa tcttctcctg tatccaccat ggcaaaatgt ccattgcttt
     9481 caagaataat cgcatcactg ccaccttctt gaacattgat aaagtggatt ttatttcctg
     9541 aactttcttg agcctgaaca ttcccatacc atgacaaacc taaaaaagcg cctacaagtg
     9601 ctaaactagt taatttcttt ttcattctta ctttctcaat ctctccaagg tttccttaaa
     9661 aatctctggg atatctgctt taaattccaa ggtcttacct gttctcggat gagtaaaacc
     9721 taaagtcttg gcatgaagaa attgtccatg tcctttcaaa gtcttgcgag gaccatagac
     9781 ctcatcacca gcgactggat ggccgatata agccatgtgg acacggattt gatgagtgcg
     9841 ccctgtctcc agttgcaact ctactaagct ataatcgcca aagcgttcca agacgtgaaa
     9901 acgcgtcact gcaggcttcc ctttagcagt tacagcctgt ttcttacggt ctttttcact
     9961 ccggccaatc ggcgcttcaa ttacaccacg atcattaggc agatttccat gaacaatcgc
    10021 ccaatatttg cggagagact ttttatcctt gagttcttgg gcaagtgcta gatgcgcatc
    10081 atcgttttta gcaatcatga gaagacctga cgtatcctta tcaatacggt gaacaattcc
    10141 tggacgcaga accccattga tacccgacaa gtccttaata tgatacatga gggcatttac
    10201 tagggttcca ctggtatgac cagcactcgg gtgcacaacc attccctgag gtttgttaac
    10261 gacagccaca tcctcatctt ggtagactat ttctagcgga agatcctcag ccacatactc
    10321 taatacctct ggttctggca catggtaagt gacgacatca ccctcttgga ctgtgtattt
    10381 agctttcttg acttgaccat tgaccaagac ctggcctgat ttaatttgtt cattcgcaag
    10441 actgcgtgat aattctgtca aatctgacaa agccttatcc aaacgcagac caccagtttc
    10501 aattttaatt tccatttatt tcctctttta gcattgcaat caataaaata atcactccaa
    10561 ccgtcagata gctatctgcc acattgaaaa ttgcaaagtt gataaagtca aggtggaaca
    10621 tatccacaac aaagccctga ctggccctgt caataaagtt tccaagacca cccgcgatta
    10681 tcaaagtcaa acccaagacc atccagaatg agtcctccat gtgtttatgt aaataccaaa
    10741 tggcacctat cacgacaacc agagtaatga cagcgaataa cagctgctga tcttgtaaga
    10801 tagaaaaggc tgcacctcga ttttgcaggt aggtcaagct aacgaaattg ggaatccagg
    10861 agcgcacttc acccagtgga atctgctgga cgatatagga tttgaccaac tgatccagcc
    10921 caattaaaag cagtacaatg actgccacta ttgctctttt tttcatgatt tcctcttttg
    10981 atcaaaatat tcttgcatga cttctacgaa gagagtccca gcttgactaa gctccacttc
    11041 ttcacgttta acatagacca tgcggttatc taggttatcc ttgagacgaa taactgtaat
    11101 gccattaaca ctgtcactat ctaaaaatcc agaacctgtc gcataggcgt ccgtccgctc
    11161 caaaatacca ttcaaggtgg cacggtctgt cacattaaac atctgtgagc tagcgctggt
    11221 atcgacaaag ttctctgaat aataaaggta ctcgtctttc tcttgagtga aacgaaccgt
    11281 tggtaaatcc gctaaatcct ccatgactaa ttcctctttc cgagctaaag gatgaccctc
    11341 acagagataa atatgggtat ggaaaggaat caattcgatg acctccagac ctaacttttc
    11401 aacccgttgc ataatcccct ttttattttg attgttgagg tagataatcc caatctcact
    11461 atgcccttgc gccacttcat ctaatatttg aacagtagtt gattcaaaaa tacggaagtt
    11521 cttatagtca ggatagcgct ctgaaaaggc cgtaatagtt ggtggtaaga agtcatagtg
    11581 ctggctagca acggaaaatt catctttttc ttcttcagga ttggcatact gattttgaaa
    11641 aatatcaaat cctttaacca attcttgcgc tttttcataa aattccatcc cacgacgggt
    11701 caagaaagtc cctgagctgg tccgacggaa aatcttaaag cccaactctt tttccaaatc
    11761 acgaacagaa atagacagac tcggctgact aacatacatc ttttcagcag cttcacgaaa
    11821 agtaccacta ttggcaatag ccacaacata gcgtaattgt tgaatgttca tcttctaccc
    11881 ccaacttctt tatcttttta ttataccata ttttagaagt tttccaaaaa ggaaaaaaga
    11941 acatcctatt cttcttaact atcttcacta tctgcctttc tcacgccaat cttattttca
    12001 aaatcaattc aaaaaaataa gtggctacac accacttcag tatcggaaag aaaaacgttg
    12061 actatttgtg aaaaaagaaa atgccggaaa attccgacat tttttagtaa gctaacttcc
    12121 tgaaaatagg agtaaccaaa catcccagaa agcagtgata ttgatgagaa tatgaactag
    12181 tattggatag tagatgtttt tagtcatgcg atacaataga gccaaaataa gacctccgct
    12241 agcataaatg aaaaaagcaa gaggagttaa agcaaaattg atatgaatat aaccgaaaat
    12301 aatagcaaaa agcaagacat ctccgtacca aggcgagttt ttgaaaaagg ttgtcataag
    12361 cacaccgcga taaatcaatt cctcagcaat agggccgatg aagcaaacga tgagcaaaaa
    12421 atagggtaat tcctgtctcc ctatcatttc tatcgtttca ttcaaagaaa tttgatttga
    12481 agacagggat atgaaatacg aaaagagaaa gtcagacata tacgaagtga tgtaacccag
    12541 taaaaggtag ataaaatacc tcagctgcca cttgaaatga aaagttttct ttcctgcaaa
    12601 aactagtaga tagatgaccg ctaataaaag aactccactc tccatcaaaa gcagaatctg
    12661 aaaaaattca cgacttgctg gtagataggg ctttgcgaga taattgaaaa gcctccaaaa
    12721 ccaagttgat ttgtaaaaaa ttaaggacaa tgctagtaaa atttgaatag cccgtttttt
    12781 catattaaat tctctgcttt ctccacttgt ttcttcatat tactaataaa ttttacttaa
    12841 aatctcgcag cacttccttt gcaaagatga ttacctcctc caatatatcc taaatcatcg
    12901 gtgtctctgg gacaaaatcc atgaaccagc agagttaata ctggttccat tttccaagga
    12961 taataaccat taggttcttt accataggga tctgctccac cttgtatcag ctctaattct
    13021 tcatttgtta gatttatatt ttttgtcatt aaaatcatga tatatttcct ccgttattgt
    13081 ttagattagt tgagtaatct gctactcata cctacttaca aaaaaactat tatattaagt
    13141 tggtttttta atttgtctag ttgcaacatt gacaaacata gtatagcata tctttgccaa
    13201 atatcctctt caaatcatga attgtcatca aaacatctta aactataaaa tcaattagtc
    13261 tcaagctttc tatcaatttc ttatccaaaa tatgctataa taataccaaa agataaagaa
    13321 ggaagaccta tgattaaact actagccttg gatatggacg gcaccctcct caatgaagcc
    13381 aaggaaatcc cacaagctca cattactgct attcacaaag ccattgaaaa aggtgtcaaa
    13441 ctggttctct gtacgggtcg cccccttttc ggtgtcctcc cctactacaa aaaactgggg
    13501 cttgacctcc agaacgaata tgttattgtt aacaacggtt gttcaactca ccaaaccagt
    13561 gattggggtc tagttgactg gaaagaactg agtccagctg acatcgaata cctctatgac
    13621 cttgctgaaa agagtgatgt tcagttgaca ctttttgacg agtcacatta ttttgttctc
    13681 ggtggcaagc ccaatcaagt tattgaaaat gatgctaaac tagtattttc agacctgact
    13741 gaaatttctc ttgaggaagc gactagtgga aagttccgga tgttccaagg tatgttttta
    13801 ggaacaaaag aacaaacaga cgattttgag cagcgttttg ctgaagagct ttgccaacga
    13861 ttcagtggag ttcgttcgca gcctgtcatt tatgaagcaa tgccacttgg aacgacaaag
    13921 gctactgctc tttcacgact agctgagatt ttgaagattg attcctcaga gattatggcc
    13981 atgggcgatg ctaataacga tatcgaaatg ctccagtttg cagggcttgg gattgcaatg
    14041 ggaaatgcca gcgattatgt caaatctctt gcggatgccg ttacctcaag caacgaagaa
    14101 gacggcgttg cgcgtgctat tgagaaatat attctataaa aaagaaaagc aaatagacag
    14161 aagttactgc tatttgcttt tttgctaata ttttaaaata cggactaatc aatagacaag
    14221 aatagcgaat cataaaaatc gatttactag atgccatagt atcttatagt tgctaataag
    14281 aagttagtct agcagaatga atctctcatt tctcccacac taatctgtaa tttgtctata
    14341 catttctggt cttctatctc gaaacaagcc ccagtttaga cgttcacttg ctcccttgtc
    14401 taggtcataa gtagctaaca gaacagcttc ttcttgtctt tcagctcgtt ctagaatagc
    14461 tcctgtttca tccgtcataa aggaggaacc gtagaagtca agactggaac tctgtccgcc
    14521 attttcctca ctaggagtaa cctcctctaa accataacga ttggctgcga tgactggaac
    14581 aatattcgct gctgcgtgcc cttgcatagt acgttgccag tgaccacaac tatctgtatc
    14641 caaaattggc tctgaaccga tagctgtagg ataaaagagc aattcagcac cattcaatgc
    14701 aagacagcgc gctgtttcag ggaaccattg atcccaacag ataccgatac caatcttagc
    14761 atagcgagta ttccagacct tgaaaccagt gttaccaggc gtgaaataga atttttcttg
    14821 ataataatgg tcatctggta tatgggtctt tcgataaacg cccagcactt ccccatctgc
    14881 atcaatgacg gcaatagagt tatacaagac attaccatct ttttcataga aactgattgg
    14941 taaaacaact tgtagttcct tagcaatcac cttaaaatgc tgaatggcag tattttccgc
    15001 tacagattgg gcatactggt agtagtcata ctgacgttcc tgacagaaat agggatgttc
    15061 aaacaactcg ggcaagagaa taatttgggc tccttgctca gcagcctgac gtactaaacg
    15121 ctctgcggtt tggatatttg ttgccacatc cttagcgcat tgcatctgaa tggttgcaac
    15181 tcttacattt ctcatctttt tctcctattc tggaatttgt tgggtgatac agtggatatt
    15241 gccaccacct aagagaatat ctctggctgg tattccgaca actttacggt ctgggaaaca
    15301 cttgctgagg atatctaagg ccacttggtc gtttacatcc tcaaactgtg gaaccaagac
    15361 agccttgttg gcgatataaa agtttacgta ggaagctgct agtcgttcac ctgcgtatcg
    15421 ctcttcttct ccttcttcat agatgtagcc tggcaaatct tcttctgtca caacttgtcg
    15481 aactgcaggg ataggcaatt tatgaatggt gaagtgacaa ccttttgcat ctgtttcctg
    15541 ttctaagagt tcgagatctg cttttgacat ggcatactgg ggatcatttt cgtcatctgt
    15601 ccaagccaaa acaacctcag caggaccaac aaaggcagca acattatcga cgtgttcatt
    15661 ggtttcatcc tgataaatac cataaggaag ccaaataact ttttcagcac caagactttc
    15721 taataatgtg ttttcaatct cctctttagt caagttagga ttgcgaccag gactaagcaa
    15781 gcaactttca gttacgagaa tagttccttg accatcgcta tggattgcgc ctccttccag
    15841 tacaaaaggt ttagcatcat agacaggcct ttccaaggcc tcagcaaaac gactggctac
    15901 ttggtcatcc tcttcataat cttgataaag accatcatag gtgcctcccc aagcattgaa
    15961 ggcccaatcc acggctaatt tcttaccttt gtcattgacg agaatggttg ggccagtatc
    16021 acgcgcccag gcatcattgg tgggaatgtc taaataaaca accttgtctc caagatagga
    16081 ttgggcttca gatagatagg cctgctccac caaaagatag actctttccc cttctgctat
    16141 agtctcgatg atctgagtaa atgctctttt agcatccttt ccttgaaaag gccatgatcc
    16201 tggtcgagtc ggccatatca tgagggtacc atgatggggt tcgtactctg ctggcatgtg
    16261 atagcctaat ttttttggac tgtccatcat gataatctcc ctttaaagtc ttgatagcca
    16321 aaagctttga gtaagctaca gtctccctgt tcgtccatga gatagagact tggcaatcca
    16381 ataccattaa aggtattatt tttgacaaaa gaataaatgg ccatgtcttg aaaataaagt
    16441 ctgtctccga tttggactgg attttcaaaa ctataatcac caatcacatc gcccgtcaga
    16501 caggtattag aagaaagtct gtaggtatgg gctttttcct gtgcctcaaa gccatttctc
    16561 aaaggtggac gatagggcat ctcaagtaca tcaggcatat ggcaggtcgc agaggcgtct
    16621 aaaaccaaga tttccatacc gttttctaca atatctaata cctcagttgc taaataaccc
    16681 gcattaagcg caatggcttc accaggctcg atatagattt caagattgta agtttttcgg
    16741 atacgcttga tttctgaaat cagcaaatcc acatcgtaac cttctcttgt aatatgatga
    16801 ccaccaccca tattgagcca ttttacctca tgtaagtagg gaccaaactg ttcttctact
    16861 gctttcaaag ttgtttgtaa atcatctgct ccctgctcgc aaagggtatg aaaatgaagt
    16921 ccgtcaacca aatctagcaa atcactcgga atcttgtcta tagtaactcc aaagcgagaa
    16981 cctggtgcac aagggtcata gagcgcgtga tctccttgag ttgaacactg agggttgagg
    17041 cgcaaaccaa cactgacacc agcctctcga caacgcgaac catgcttacg caactgtctc
    17101 tctgagttaa agacgatatg gtctgttatc ccaagcaatt cctccatgtc ctcatccttg
    17161 aaagctggtg caaaaacatg gacttcacca ggaaattctt cccttgccaa tttggcctca
    17221 tagagtccac tagctgtcgt acctgataga tactggctaa tcaagggata agttttgtag
    17281 agggaatatg ccttctgggc aagcaagacc ttgcaaccgg cctcttcttg tacatattgt
    17341 agaatgcggc aattagcttc taacttggcc aagtcaataa cataggctgg tgttggtact
    17401 tgttctaact tcattagtcc accatttgtg gattttcaac cacaacccat ggcaaaccat
    17461 actcattcaa agcttccatg aatggatctg gatctaactc ctcaaggtta tacactccag
    17521 cttgtttcca agttccgttc atgactaatt ttgtcccaat catggctgga actcctgtcg
    17581 tataagaaat agcttgcgaa ccaacctctg cgtaacattc ctgatggtcg cagacattgt
    17641 agatatagat agtctttttg acaccgtctt tgacacctgt aaagatacat ccaatattgg
    17701 ttttacctac agtacgtgga ccaaggctag caggatctgg aagcaaggct ttcaaaaatt
    17761 gaattggaac aatttcttgg ccgttaaagt taatggtatc cgtacgaagg agtccaacat
    17821 tttcaagaca tttcatgtgc gtcaagtaag attgaccaaa agtcataaag aaacgaatgc
    17881 gtttgacacc tggaatgttc ttggccaatg attcgatttc ttcatggtga aggagataca
    17941 tatctttttg tccaacttga gggaaatcat actcacgctt gatagacata gcttcgactt
    18001 cgacccattt cccatcttcc cagtaagaac ctggcgcaga aacctcacgg agattaattt
    18061 ctggattaaa gttggttgca aatggataac cgtggtcacc gccattacag tctaaaatgt
    18121 cgatataatg gatttcatca aaatagtgtt tgagggcata agctgaaaag acactagtta
    18181 cacctgggtc aaaaccagaa ccaagaagag cagtcaagcc tgcttctttg aatttctctt
    18241 gataagccca ctgccatgag tagtcaaagt aggctgtaaa accaagttcc ttacaacgtt
    18301 tttcgtagat agcacgccac tcagggtctt ctgtgtcttc tgcttcgtag ttggctgtat
    18361 cgatatagtg aacacctgtt gccaaacaag catccataat ggttaaatct tgataaggca
    18421 gagctacatt caaaacagct tctggtttgt agctttcaat cagagcaatc acttcttcaa
    18481 ccttgtcagc atcaagagca gctgtctcaa tctttgtact tgttttgcct tccagtttag
    18541 ctttcaagtc atcgcatttt gacttggtac ggctagcaat cataatctct gtaaatgttt
    18601 cgctatcttg acaaatcttt gaaatagcaa cttgggcaac gcccccacaa ccaataacta
    18661 gtaaacgact catttttttc cttcctcttc ttctaaaatg tcctcaacat acttgggcaa
    18721 cataaaggct cccacgtgta agtttgcagt gtagtattct gtgaaaagct ggcgtttttt
    18781 ccagccttcc ttgtcaaaat ctttgacagg gtggtatttt ttcgatgcaa atccaaacaa
    18841 ccaatagcca gctgggctag ttggaatatg ggcctgataa acccgactga ttggaaaggc
    18901 ttgattgacc ttgcggtgca tgcttcggca ggccgactca tcctcgtcaa agaacggact
    18961 cccatgctgg taaatcatga tgccgtcttc cttcagagct cgataactat tgccgtagaa
    19021 ttccttggta aagagtcctt ccgtatggcc aaatggatct gtcgcatcgt tgatgataat
    19081 atcatagtca tattcgcagt ttcgcaaaaa gcgtagccca ttttggtagt aaatggtaac
    19141 acgaggatca tctaggcctg cagcaaagtc tgggaaatac tcacgacaga cctcgaccaa
    19201 catctcatcc ggttccacga tatcgatttg ttccagttca ggatagagtg ttaatacttg
    19261 ggcaacaccg ccgtcaccac ccccaataac caatactttc tttggatttg ggtggacagc
    19321 catgggaacg tgaacggtca tttcattgta gacgaaatca tccgcatctg agaacaagac
    19381 atggccattt aaaatcagta ttttcccaaa agctggcgta tccaagactt cgatatcctg
    19441 ccattcactt tttccagcgt aaagttgctt ggctgttctc agagacaatt tgacatctgg
    19501 agtatgaact tcagaaaacc ataaatccat ctatttctcc ttatattata tttagcgcag
    19561 ttagctactg ccaaagccca agtggtatac ttggaataag ccactgtgga ttagttcatt
    19621 tcctccaatc acttgacgat ttccgaaagg gtctaaccac agctttttgt ttcaattggt
    19681 aatgagtttg ataacgcata gacgttttat ctcgtctaag gtaacaaggc aaaaagttcg
    19741 tggataacca agtagacttg aaatactata tctggaggta ctcccatgct ttatgtgggc
    19801 attgatgtcg ctaaaaataa acacgatgtt acagccttga atgttcgagg aaaactgttc
    19861 ttaaaccact cactttttca aataataaag ctggttttga actcttagat ctgtctcttc
    19921 gacaactcaa ccaagactgt ctcatcgctc ttgaaaatac cggacattat gcctttaatc
    19981 tactgaactt cctgcatgaa caaggatata aagtttacac ctacactcct ttgctcatca
    20041 aggaatttgc caaatcatta tcacttcgca agactaaaac ggataagaaa gacgctcatg
    20101 gcatcgctct taaacttctt tctgacccca atcgtgaaca atttcaacac gataatcggc
    20161 aagtagaact aaaaatactg actagacata ttcatcgtct caagaaaaaa cagtctgatt
    20221 ggaaagtaca atacactcgt tgtcttgata tcatctttcc tgagttggat aaaatcgttg
    20281 gaaagcattc agaatatacc taccaactct tgacacgcta ccctaatcct cagaaaagga
    20341 ttgaggcagg atttgataag ctgatagaaa ttaagcgatt gaccgcttct aaaattcagg
    20401 atatcctctc agtcgcacct cgttctatcg gaacaacatc tcctgctcgt gaattcgaaa
    20461 tcatcaaaca ttacaagagg ctcattgaca aggcggaaac atgtgtcaat gacttgatgg
    20521 ctgagttcaa ctcggtcatc acgacggtca ctgggattga gaatcgttta ggggcggtca
    20581 ttttagccga gattcgaaat attcatgcct ttgataatcc tgctcaatta caagctttcg
    20641 ctggactgga ttcttctatt tatcagtcag gtcagattga tttagctgga agaatgatca
    20701 aacggggttc ccctcatctg cggtaggcac tcatacaagc tgccaaagca tgccctcgct
    20761 tttcacctgc ttttaaggcc tatcttaaga ctaagttaga ataaggaaaa cattacaatg
    20821 tagccatcat ccaccttgca aaaaaactta tccgaaccct gttttatatc ctaaaaaaga
    20881 gctgccattt gacgaacaaa aagtgatgta atttctgaaa ttaacacagg attacctttg
    20941 aaaaaatgga ctttttcaag agctttttgc catgctctaa aatcatcgcc aaatcatcaa
    21001 attgaaataa gaaatagttt agataaaact attgactttt cttatagttt gtctttctct
    21061 taatgacgtt gatgtgattg acctctggat cttccgtccc ttggagggag caaccacgtt
    21121 ccttggcaaa ttggatatag tcgacaattt ctcgtgtgat gcgttcgcca ggagccaaga
    21181 tagggattcc tggagggtaa cacatgacaa attccccaca gacctgtcca acagattcgt
    21241 ccaaggtcaa actttttctc tctgaataga aggcttcttg cggagacagc actaactcgg
    21301 gctgaatata ttctcctgct atcaaatctt ttccatctct tgaatagagt ctcttaatat
    21361 cagccagagc accaaccaag cgctcgatgt cttggatgcg gtcgccgatg gaaatatagg
    21421 ccaagatatt gccgatatca ccaaactcga tctgaatgtc gtattcgtct cgcaagaggt
    21481 cataaacctc gatacctgtt aagcctattc cctgagtgta aactgacaac ttggttacat
    21541 caaaatcaca gaccgacaca ccatctatta actcttttga gtaagcatag taaccgccaa
    21601 tggtattgat ttcatgacga gcgtactcgg atagctcaat gacttcctca aacgactctt
    21661 taccacgaag ggccaagttg cgacgtgaaa tatccaaact agccatcaat aagtaagagg
    21721 cagatgtaga ctgggtcagg tttataatct gacgaacgta ctcgggattc atctgctccc
    21781 cgattaaaag aagcgaactt tgtgtcaaac tcccaccaga cttatgcatg gaaactgctg
    21841 ccatatcagc tcctgcatcc atagcagaaa ttggaagttt accagtgaaa tgcaaatgcg
    21901 ctccatgggc ttcatctact aaaaccatca tgccagcttc atgagccatt tctgtcaacc
    21961 cctttaggtc tgaacagatg ccgtagtaag taggattgtt gattaggata gccttagcat
    22021 ctggatggtc ctttatggcc tgtgctactc ggtcattttc aagacctaaa gcgataccaa
    22081 tcttaggatc tacactcatc tcgatataga tgggaatggc accacataga accaacgcat
    22141 tgatagcaga tttatggaca tttcgtggca gaataatctt atctcctgcc ttgcaggttg
    22201 ccagaatcat agtctgcacc gatgaagttg ttccaccaat cattagaaag gcatggctag
    22261 ctccaaaagc atctgcagcc agctcctctg catcacgaat aatcgaaata ggatggccta
    22321 aattatccaa gggtttcatc gaattgacat caatgcctac acatttttct cctaagagtt
    22381 cgacaagttc tggatttccc cgtccacgct tgtgacctgg aacatcaaag ggaacaatcc
    22441 ttttcttgcg taacttcacc aaggcctcat aaattggggc ttggttttga tctaactctt
    22501 tcaaaacata ctcctttcaa tatttttagg accttatgaa aactaaggaa ctaaaggttg
    22561 actcatgaaa aaagagcagg ttttcacctg ctctgcaatc ttctgacgtg tttattttgg
    22621 tttctgttga gtatgtctgt tcccgatgtt tcctaactct ctagtagcaa atattacgta
    22681 ctttattgat cgtttcacaa gatgacgtgt gctttcacca cactaaaaat ttatgaatta
    22741 gaacaagtgt cctaacatca acttataaaa gtaggctttt aaccctatca ataatgtggc
    22801 ttttcaacca cgcttcggca ttcaaccctg cctgtccgta ggcatttttt actcgggttt
    22861 atatttgcta gaaaacatca tctcattttc taagctttat tactatatca tgtttttaag
    22921 aacttgtaaa gtattttttg ataaaaaata aaaatatagt agattgaaac tagaatagta
    22981 cacctctgct tctaaaacat tgttagaaat agattttact gtcctgatcg atttgttctg
    23041 ttcttgtttc attttactat atgttcgtaa atgaaagttc tataatgaag ttagccaccc
    23101 agccctccta aaaattagat ggttcaacta gccgatagct cttgtaggca taagaaaaca
    23161 cctctgtgtt atacttgttg ttcaaccaca aacacaagaa aggcgcagag atgcaagacc
    23221 attatactac aaaaggcgaa caaagggaaa tcaaatagag aaattgcctc tctgcttgga
    23281 aaagttcctc aaactatcca cactgaaatc aagcgtggga cagtccgaca atgtcttgga
    23341 aaagggcgct tcaaagaggt ttattctgcc gactatgctc aacagtctta tgaaaacaat
    23401 cgcaagcgct cggtcaagaa atcaagcttg accaaggaac taaaggaaaa gattctccac
    23461 tatcataacc aaaaattttc gcctgaaatg atggttatgg ctaaaggggt taacgtggga
    23521 atttcaacca tttactattg gattcatcat ggaaaattgg ggttaagcaa gcaggatttg
    23581 ccttacccta gaaaaggaaa agcgcttaag aaacaggcta gcaccaactt taaacctgct
    23641 ggtcaatcta tcgaacagcg gt
//
LOCUS       DBJKQU010000028        23111 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.028, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000028 DBJKQU010000000
VERSION     DBJKQU010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23111
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.028"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            1..785
                     /locus_tag="ACSUUC_001281"
                     /pseudo
     CDS             1..785
                     /locus_tag="ACSUUC_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            788..985
                     /locus_tag="ACSUUC_001282"
                     /pseudo
     CDS             788..985
                     /locus_tag="ACSUUC_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252110.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
     gene            complement(1057..1299)
                     /locus_tag="ACSUUC_001283"
     CDS             complement(1057..1299)
                     /locus_tag="ACSUUC_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HHQ8054490.1"
                     /translation="MKKDIHPEYRSVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(1395..2330)
                     /locus_tag="ACSUUC_001284"
     CDS             complement(1395..2330)
                     /locus_tag="ACSUUC_001284"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HHQ8054491.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            2434..2877
                     /locus_tag="ACSUUC_001285"
     CDS             2434..2877
                     /locus_tag="ACSUUC_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HHQ8054492.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            2993..3259
                     /locus_tag="ACSUUC_001286"
     CDS             2993..3259
                     /locus_tag="ACSUUC_001286"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HHQ8054493.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            3256..3630
                     /gene="crcB"
                     /locus_tag="ACSUUC_001287"
     CDS             3256..3630
                     /gene="crcB"
                     /locus_tag="ACSUUC_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HHQ8054494.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            3624..3953
                     /gene="crcB"
                     /locus_tag="ACSUUC_001288"
     CDS             3624..3953
                     /gene="crcB"
                     /locus_tag="ACSUUC_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HHQ8054495.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            4072..4419
                     /gene="rplS"
                     /locus_tag="ACSUUC_001289"
     CDS             4072..4419
                     /gene="rplS"
                     /locus_tag="ACSUUC_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HHQ8054496.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            4461..4532
                     /locus_tag="ACSUUC_001290"
     tRNA            4461..4532
                     /locus_tag="ACSUUC_001290"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4494..4496,aa:Arg,seq:cct)
     gene            complement(4587..5393)
                     /gene="yidA"
                     /locus_tag="ACSUUC_001291"
     CDS             complement(4587..5393)
                     /gene="yidA"
                     /locus_tag="ACSUUC_001291"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HHQ8054497.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(5406..6710)
                     /locus_tag="ACSUUC_001292"
     CDS             complement(5406..6710)
                     /locus_tag="ACSUUC_001292"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HHQ8054498.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            6782..7159
                     /locus_tag="ACSUUC_001293"
     CDS             6782..7159
                     /locus_tag="ACSUUC_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HHQ8054499.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            7250..7582
                     /locus_tag="ACSUUC_001294"
     CDS             7250..7582
                     /locus_tag="ACSUUC_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HHQ8054500.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            7594..9165
                     /gene="ffh"
                     /locus_tag="ACSUUC_001295"
     CDS             7594..9165
                     /gene="ffh"
                     /locus_tag="ACSUUC_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HHQ8054501.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKMDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(9360..10643)
                     /locus_tag="ACSUUC_001296"
     CDS             complement(9360..10643)
                     /locus_tag="ACSUUC_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease family protein"
                     /protein_id="HHQ8054502.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKKRVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(10897..11610)
                     /gene="rsmG"
                     /locus_tag="ACSUUC_001297"
     CDS             complement(10897..11610)
                     /gene="rsmG"
                     /locus_tag="ACSUUC_001297"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HHQ8054503.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            11704..12264
                     /locus_tag="ACSUUC_001298"
     CDS             11704..12264
                     /locus_tag="ACSUUC_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HHQ8054504.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            12266..13165
                     /gene="htpX"
                     /locus_tag="ACSUUC_001299"
     CDS             12266..13165
                     /gene="htpX"
                     /locus_tag="ACSUUC_001299"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HHQ8054505.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(13314..14873)
                     /locus_tag="ACSUUC_001300"
     CDS             complement(13314..14873)
                     /locus_tag="ACSUUC_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHQ8054506.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQSVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(15112..15428)
                     /locus_tag="ACSUUC_001301"
                     /pseudo
     CDS             complement(15112..15428)
                     /locus_tag="ACSUUC_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
     gene            15598..16140
                     /locus_tag="ACSUUC_001302"
     CDS             15598..16140
                     /locus_tag="ACSUUC_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceD family protein"
                     /protein_id="HHQ8054507.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16140..16769
                     /gene="nth"
                     /locus_tag="ACSUUC_001303"
     CDS             16140..16769
                     /gene="nth"
                     /locus_tag="ACSUUC_001303"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HHQ8054508.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKLSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            16980..17501
                     /gene="pyrR"
                     /locus_tag="ACSUUC_001304"
     CDS             16980..17501
                     /gene="pyrR"
                     /locus_tag="ACSUUC_001304"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HHQ8054509.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            17520..18443
                     /locus_tag="ACSUUC_001305"
     CDS             17520..18443
                     /locus_tag="ACSUUC_001305"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HHQ8054510.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            18493..19572
                     /locus_tag="ACSUUC_001306"
     CDS             18493..19572
                     /locus_tag="ACSUUC_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HHQ8054511.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            19885..23061
                     /gene="carB"
                     /locus_tag="ACSUUC_001307"
     CDS             19885..23061
                     /gene="carB"
                     /locus_tag="ACSUUC_001307"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HHQ8054512.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLSSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         6687 a         4430 c         5194 g         6800 t
ORIGIN      
        1 ctttcttgct cgccatttga aggctgcaga ggcaggagaa tttgttacaa ttgatgcctt
       61 atttcaggct tataaaaagg agttaggtcg ttcctacaca cgtgatgcct tctatcaatt
      121 gttgaagcgc catggttggc gaaatattac gccacgtcca gaacatccta ggaaagcaga
      181 cgctcaaacc attgtcgcat ctaaaaataa aatctcaatt caagaagaca agaaagcgct
      241 ttaaaaccag tagacgtttt cataaggttc gcttgatgta ccaagatgaa gctggtttcg
      301 gtagaatcag taaactggga tcttgttggt ctccaatagg agtaggtcca catgtccata
      361 gtcactatat acgagaattt cgctattgtt atggagctgt tgatgcccat acaggcgaat
      421 catttttctt aatagctggt agatgtaata ctgagtggat gaacgccttt ttagaagagc
      481 tttcacaagc ttatccagat gattattttt tactcgttat ggacaatgct atatggcata
      541 aatcaagtat cttaaagatt ccgactaata ttggttttgc atttattcct ccatacacac
      601 cagagatgaa ccccattgaa caagtgtgga aagagattcg taaacgtgga tttaagaata
      661 aggcctttcg aactttggaa gatgtcatga atcaacttca agatgtcata caaggactgg
      721 agaaggaggt gataaagtcc atcgttaatc ggagatggac tagaatgctt tttgaaagca
      781 gatgagtata agtcctcgtt ttgaagcctt ggaacaggct attgccttca aagatttgga
      841 aaaagtccga gaagctttta agaaaatgaa ttccacttgg accatcaatg aaagtgtggt
      901 tcgttacaat agtatagctc attatggacg tgttgaaaca gctatttcct tcctgcctag
      961 tagcatggaa accgaaccta cagatgagtc tggaacatga aaacagcagt tgatttcaag
     1021 aaacaaaaaa gaacagccga aactgttctc ttatcattat ttgagaccgt attttttgtt
     1081 gaaacgatcc acgcgtccat ctgcttgagt gaacttttga cgtccagtgt agaatgggtg
     1141 tgagtctgat gaaatttcca cacggatcaa tgggtaagtt tcgccttcga actcaactgt
     1201 ttcgttagag cgttttgttg aaccgctaag gaattggtaa ccagtagttg tgtccatgaa
     1261 gacaactgag cgatattctg gatggatatc ttttttcatt ttgcaatatt tcctttctgc
     1321 catggtctct ttgcgagcca tagattgtta ccatactagt ctatcagatt ctgaaaagtt
     1381 tggcaagtat tttatcagtt tttaagcaag ttttttaact tttggtagat gatttcgttt
     1441 tcttctaggc tataggaatt agcaccactt gctagagggt ggcctccacc atcatgctcc
     1501 ttggcgattt cattgatagg atggatttta ctgcgtaagc gaacgcggta gtggccatca
     1561 gcctgttcga caaaaattcc ccagagactc actctgtcaa tgcgtccagg tgcaccgaca
     1621 atggctgcag tttcagcatc ggttacattg tattgtttca agacttcttg actcaggata
     1681 acgcgagcag caccattttc atccacttcc agatggtcgt agatgtagcc ttgcagttta
     1741 gcaattttgt agctcatagt gtccattttg cgagtgagag ccgcaaagtc aaagttatgt
     1801 tctctcaaat aagcagccag gcgaagagtc cgtgcagtgg tagaagggta gaggaagcga
     1861 cctgtatcac cgacaattcc tgcaaagagc aactcagcat cgcgatctgc caaggctagt
     1921 tgggttgttt gggcaaatag ggtgatcatc tcgctagcgc tacttgaact agtatcgacc
     1981 caagacaggt caccgtatac atcatcattt ggatggtggt caatcttaat gagaaaatca
     2041 ccttgactat agcgcttatc atcgatacga gcagtattag ctgtatcaca gacgatgaca
     2101 agtgcgcctt ggtaggctct atcttcaaca agatccatct cagccatcca agtaagagtt
     2161 ggttcatcaa aaccgacggc tttgatggtt ttttctggga aatgatgttc cagcaaggct
     2221 ttcaatccca cctgacttcc taaggcatca gggtctggtt tcatatgacg atgaatgata
     2281 atggtgtcgt attctttaat tttttctaaa atttgttggc aaatctccat aaataacctc
     2341 aattctttct catttcattg tagcacaaga atttttattt ttaaaatgaa aaagatgtga
     2401 tataatggag aaagataaat tgaggaggac gatatggcat tagcaaaaat tgtatttgcc
     2461 agtatgaccg gtaataccga agaaattgca gatattgtag cagacaaatt acgtgacttg
     2521 ggcttggatg ttgatgttga tgaatgtaca actgttgacg cttcagactt cttggaagca
     2581 gacatcgcta tcgttgcgac ctatacttat ggtgatggtg aattgccaga tgagatgatg
     2641 gacttctacg aagacctagc agatctcaac ttgaatggca aaatctacgg agtggtcggc
     2701 tcaggagata ccttctacga tgaattctgt aaggctgttg atgactttga ccgtgtcttt
     2761 gtgtcaacag gagcagaaaa aggttcagag tgtgttaaag ttgatctttc tgccgaggaa
     2821 gaagatattg aacgcttgga acaattcgca gaagaattgg ttgctaaagt aggataagca
     2881 taaaagtgcg ctgatgtaat caatcagtgc atttttctta tcgagagttg ggattttact
     2941 agcctaattg atggcttttt gatacaataa ttcaaataaa ggaggagact gtgtggattt
     3001 agatattatt cgtcaagaaa tcgatcaaat cgacgaccaa attgtcaaac tgttagaaga
     3061 acgaatgcac ttagttgaag gagttgtcgc ttataagaag gcttcaggga aaccgatttt
     3121 agatactaag agagaagcag ttatttttga aaaggttaga agtcgtgtag aggacaagcg
     3181 ctatcaggag actattgtcg cgactttttc ggacatactc aaacgttcgc gtgattatca
     3241 ggatcaaaat atcaaatgaa aaaagaacaa ttttatccgc tagggatttt tctagctgct
     3301 atgttgggcg gacttgtccg ctacctagtt tccacttggt taccagccag tccagatttc
     3361 ccttggggca ctctctttgt caactatctg ggaattttct gcttgattta tcttgtcaag
     3421 ggctatctgg tctataaggg gactagtaag ggcttgattt tagcactggg gacgggtttt
     3481 tgcggaggtt taacaacttt ttccagccta atgcttgata ctgtgaagct gcttgataca
     3541 gggcgttatc ttagtttgat actgtatttg cttttgagta tcggtggagg cctgctttta
     3601 gcttactatt tggggaggaa gaaatggtaa tcgtctatct tgcaatcgcc tgtggcttgg
     3661 gagcactcgt acggtatttc ttttctcgct ataatcaagc ttctaaattg ccactcggaa
     3721 cgctcatagc taatctttta ggttgttttt taattggagt attctacaat catgtagagt
     3781 ctaaggaagt atatgctatt ctagcaacag gattttgtgg cggtttaaca actttttcga
     3841 ccttgaatga cgaacttcaa agactgctaa gtgataagaa ggtcttttat tcttacctga
     3901 ctttgactta cataggtggt ttggttgcga tttttttagg aattttgcta taaatttctt
     3961 tacttttttg tgaaaatttg gtaaactgta tcttgtgtgt aatggacgca caagaataca
     4021 gtttatccgc tgaggaagtt tcctcaagat tgacaaagat aggagaataa aatgaatcca
     4081 ttaatccaaa gcttgactga aggtcaactt cgtacagata tcccatcatt ccgtcctggt
     4141 gacactgttc gtgtacacgc gaaagttgtc gaaggtaacc gtgaacgtat ccagattttt
     4201 gaaggtgttg ttatcgcacg taaaggtgct ggaatctcag aaaactacac agttcgtaaa
     4261 atctctaacg gtgtaggtgt tgagcgtatc ttcccaatcc acactccacg tgttgaaaaa
     4321 atcgaagttg ttcgttacgg taaagtacgt cgtgcgaaat tgtactactt gcgtgctctt
     4381 caaggtaaag cagctcgtat caaagaaatc cgtcgttaat tcgactaaaa aactctgctt
     4441 ttcagcagag tttttatcta gctcccttag ttcaatggat ataacaactc cctcctaagg
     4501 agtagttgca ggttcgattc ctgcaggggg cagtaattag acatcaaaaa ccgctcagct
     4561 gagcggtttt tatctattct ttccttttac agtacccatg tacgaatagc atgggcaacg
     4621 ccggattcgt catttgtttt ggtgatgtat ttggcgattt ttttgatttc tggatttccg
     4681 ttttccatga ctacagggtt gccaacgact tccagcatgg cacggtcatt ttcttcgtct
     4741 ccgatagcca tggtttcatc tttggttaat cctagttttt cagctaagtg agtaatagct
     4801 gaacccttgt ctacattctt tttaaggagt tcgaggtaga aaggagcaga tttgttgata
     4861 gagtagtgct cgtaaaattc ggctggtatt ttttcaatcg cagcatcgag gatttctggt
     4921 tcatcgatga acatacactt gacaatttcc ttgccagcca tttcttcagg ggtacggtag
     4981 aagataggca tgctgacgag ggttgattcg tgtacagtgt attttccgat attgcgattt
     5041 gcagtataga taccgtcctt ggtaatggca tgcatgtgga caccgagctt gcgactgagg
     5101 aattccatat ccagataatc ctcataggtc aaggattcgc tgataatctc atggccagta
     5161 gcagtttctt ggacaagggc accattgaag gtcaccacat agtcaccttg gtctctcaac
     5221 tgcaagtcgt ccagaagttt ggcaacacct gcgatggggc ggccagttgc aatcacgact
     5281 ttgacaccag cttctttggc atcttggatg gcagaaaaga cttcaggagt gatttccttt
     5341 tggctgttga ctagggttcc gtcaatatcg acggcgatta gtttaatact cataaatttc
     5401 ctcttttagt ttttatttgg ggtaaaatga tcgttctcaa tcaagtgtaa aaattgctgg
     5461 gtgatgcttg cgaagatgct gttttggtct aacatttctt tcgggaaata aaagcgatta
     5521 tctccgtggc gacttccagc aagggattgg acgatagggg acaggctaga gagttctgcc
     5581 agttctccat ttttttgtaa aatctcaatc tgtgtccttg gattttcaga ttcgggacgg
     5641 taaatatcat aagggaggtc aaagttctta tgaatggcag tatagtagtc gggatcaaag
     5701 ccgatgtcct caaccaattt tctcatgcta gcgagttggt cttggtcttc ttgtgaaaag
     5761 gtaatggatt taaagacctt gcggttgaca aagcgatgcg ataaatctgc aagaatcttg
     5821 tcaggactgg tcatccagag ttggaagtag gtattcatca caccatcatc cagagccaga
     5881 tagtcagtca aggtcacatt tttttcgaag aaaggcagga ggtgtggaga agttcgggca
     5941 aagaaatcct tgtcctcagg atagagttcc ttggcgcgtt tgagaagatt ctgtaggaga
     6001 acttccatgg cgcgtgttgc ggggtggaaa taaacctgca tgtacatctg gtagcgactg
     6061 aggacgtagt cttcgatggc gtgcatgcca ttgcgctgaa aggcgatacc attttcgata
     6121 ggacgaatga ctcggaggat tcgagtcagg tcaaattccc cataggatgc tcctgtaaaa
     6181 taggagtcgc gcaagagata gtccatgcga tctgcgtcaa tctgactaga aatgagctgc
     6241 acgacctgct tgttaggata ggtatggtct atgacactgg caactttctc tggaaaatcg
     6301 ggcgctactt gtagcaagac ttggtgaatc tctgtctcag gattttgaat aatctcctga
     6361 gtaatggctt catggtctgt atcaaagaga ttttcaaaag tatgggagta ggcaccatgc
     6421 ccaaggtcgt gtaggagagc agcggtcatg gtcaagagag actcggcagg attccattcc
     6481 tcaggatatt tttcttcgaa aatctctgtg atgcgtcgtg caatttcata gactcctaga
     6541 cagtgagaga agcgactgtg ttctccaccg tggaaggtat aactggaagt tcccagttgt
     6601 ttgatccggc gcaaacgctg aaattctttt gtattaatca agtcatagat gatttgatta
     6661 ttgacatgga tgtagttgtg aacagggtca cggaatactt tttcgttcat atgaccatta
     6721 tagcaaaatc ctgctctttt tggtaaaata gtaggacaag agacaagaaa gagggcctga
     6781 tgtgaagatt cggatgcgaa atacaattca gtttgatgag cagttggaag tgattgacca
     6841 gctttatgat gtggaagtgc atgaaaaagg agattatagc tacctgcttt tctataatga
     6901 ggaaaaggaa aaagtagtga ttaaatttca tggtcaagaa cttatgatga gccgattttc
     6961 taatcccaag accattatgc gctttctaaa ggatagcgat agtttagcct atattcctac
     7021 acctatgggc atgcaggagt ttatcatcca aacgagccat tatcaagttg ataggcaaaa
     7081 gattgaacta gattatcaac tacaaaatca agagggacat ccttttgcca gctatcaatt
     7141 ggaaattact tggggctagg ctcatgtctt tttcaaattt agctatctat cttcttggat
     7201 cggcttccta gtgtggtaga ttaggctaat ttttggtata ataaaagtta tggaaatcga
     7261 aaaaaccaat cgtatgaatg cgctctttga attttatgcg gcgcttttga cagataagca
     7321 aatgaattat atcgagctct actacgctga tgattacagc cttgctgaaa ttgccgagga
     7381 gttcggtgtc agtcgtcagg ctgtctatga caatatcaag cgaacagaaa agattctgga
     7441 agattatgag atgaaattgc acatgtactc ggattatatt gtccgcagtc agatttttga
     7501 tcagattttg gagcgctatc ccaaggataa ctttctgcag gagcagatag aaattttaac
     7561 aagcattgat aatagagaat aagaggaaga aaaatggcat ttgaaagttt aacagaacgt
     7621 ttgcagaacg tctttaaaaa tctacgtaaa aaaggaaaaa tctctgaatc tgatgtccaa
     7681 gaggcaacca aagagattcg cttggccttg cttgaagccg acgttgcctt gcctgttgtg
     7741 aaggatttta tcaagaaggt tcgtgagcgt gcagtcgggc atgaggtcat tgatacactt
     7801 aatcctgcgc aacagattat taaaatcgtt gatgaggaac tgacagccgt tttaggttct
     7861 gatacggcag aaattatcaa gtcacctaag attccaacca tcatcatgat ggttggttta
     7921 caaggggctg gtaaaacaac ctttgctggt aaattggcca acaaactcaa gaaagaagaa
     7981 aatgctcgtc ctttgatgat tgcggcggat atttatcgtc cagctgccat tgaccagctt
     8041 aagaccttgg gacaacagat tgatgtgcct gtctttgcac ttggaacaga agtaccagct
     8101 gttgagattg tacgtcaagg tttggagcaa gcccaaacta atcataacga ctatgtcttg
     8161 attgatactg cgggtcgttt gcagattgat gagctcctca tgaatgagct tcgtgatgtg
     8221 aaagcattgg ctcaaccaaa tgaaatcttg cttgtcgttg atgctatgat tggtcaggaa
     8281 gcagccaatg ttgcgcgtga gtttaatgct cagttggaag tgactggggt catccttacc
     8341 aagattgatg gcgatactcg tggtggtgct gctctgtctg ttcgtcacat tactggaaaa
     8401 ccaatcaagt tcactggtac aggtgaaaag attacggaca ttgaaacctt ccacccagac
     8461 cgcatgtcta gccgtatcct tggtatgggg gatatgctca ctttgattga gaaagcttct
     8521 caggaatacg atgaacaaaa agcccttgaa atggctgaga agatgcgcga aaacaccttt
     8581 gattttaatg atttcatcga tcaattagat caggtgcaaa atatggggcc gatggaagac
     8641 ttgctcaaga tgattccagg tatggccaac aatccagccc ttcaaaacat gaagatggat
     8701 gaacgccaga ttgctcgtaa acgtgccatt gtgtcttcga tgacacctga agagcgtgaa
     8761 aacccagatt tgttaaatcc aagccgtcgc cgtcgtattg ctgctggttc tggaaataca
     8821 ttcgtcgaag tcaataaatt catcaaggac tttaaccagg ctaaacagct catgcagggt
     8881 gttatgtctg gggatatgaa taaaatgatg aagcaaatgg ggattaatcc aaataacctt
     8941 cctaaaaata tgccaaatat gggaggaatg gatatgtctg cccttgaagg aatgatggga
     9001 caaggcggta tgcctgactt atcagctctc ggaggagcag gaatgccaga tatgagccag
     9061 atgtttggtg gcggtttgaa aggtaaaatt ggtgaatttg ccatgaaaca gtccatgaaa
     9121 cgtatggcta acaaaatgaa gaaagcgaag aagaaacgca agtaagacaa gagattgatg
     9181 caaatctcat ttgatgagaa aataaagtaa aaatttctat gataaaacgt acagtatcaa
     9241 ggttttagaa tatctgatat tatacgtttt ttgattttaa taattttgtt aagacacttt
     9301 tattatggta tgcgaaaaat ccactcagct gtctgagtgg attaggtgta tttagactct
     9361 tagtctttat tttcgtatgg caagatcaag ttcaagatga ttcctgtcat ggctgaaagg
     9421 gcagtacctg aaagtgtaac tggaccaagt ttaaggatag ctcctccaag tccaagaacc
     9481 aacatagcac ttgcgatgat gaggtttcgc atttgagcga aatcaacacg ttttttaatc
     9541 aagactttca aaccattgct ggcgataacc ccatagagaa ggattgacat accaccaagt
     9601 acagcgtttg gaatagttga aatcaaggca gtgaatttac caaggaagct gagggcaatc
     9661 gcgatgaagg cagcgttacg gataactgag acagaagcga tacgagtcat accgataacc
     9721 cctgtatttt ctccgtaagt tgtattggct ggtccaccaa ggaaggcaga aacagaagtt
     9781 gcgataccgt caccaagaag agtacgatga agacctggtt cttttaagaa ttgacggcca
     9841 cagatttgac ccaaaacagt atggtctccg atatgttcag aaattgttac gatagcgatt
     9901 ggcaagatag cgatggcttc tggaccaaag taaagattgt actctttaaa ggcaccacct
     9961 gtgctaaatg gcaagtagaa accaggaatt tcgaaccagt tggctttaag aactggtgta
    10021 aagtcaacca agccaagagt tagtgcgaaa aggtaaccac cgataatggc aaagaggaat
    10081 ggaatgattc gtaggaagcc ttttcctttt gtattgataa aggcagcaat taggaaagta
    10141 acaacggcta ccagagcatt tttccaattt ccgtctgcta caagacctgc attggtaaca
    10201 gctgaacctg caagtccaag accgataacg atgatcatag gaccgataat gattggtggc
    10261 aagagtttat caatccattt tgttcctaca aatcggatgc tggtagcaac aaggacatag
    10321 accaaaccag tcaagataac ccctgtttgg gcagcagata catcaccccc catttctttc
    10381 atagccagtg acatagctgt gataaaggca aatgaagaac ctagataaac tggaacttta
    10441 aaaccagtag caatcatgta gatgagtgtt ccaacacctg aagcaaaaag ggcaacagat
    10501 acaggcattc ccaaaatcaa tggtaccaag atggtcgcac caaacatggc gaaaacgtgt
    10561 tggaagctaa ggagaattcc ttttccatcc gaaggacgtt ggtcaacgtc tagtaacaaa
    10621 tcaacagttg attcttgttt catataaacc tcacttttgg gcatcagaaa agagcccatt
    10681 attttacagc aataggccct cagagtaaga cttctctaaa atctagactt taaagagttt
    10741 caaatatttt tgcgtcttcg tcacctcacg ggatgacatt aaaaaccttt gcttaggata
    10801 gtatagcaga aaaaaatgat tttgtaaatc attttttccc gagcctagaa ataaaagagc
    10861 gaggctgatt ttgtaaacat ttgtttacta aaaaatttaa agtgggcgtt tatttggcat
    10921 accagcctta cgtggatatt tatttggtgt ttcttttttc ttttctacca ctgtgatata
    10981 gcgcggatct ctattcggta gggcgtagct gagattgtct tcgaccttac taaaaaggag
    11041 attgagggca ttcttagctt ctaataattc ctcaggcgca ttgctggcct tgagtgccaa
    11101 tagtttgcca ccaaccttaa ggtagggaat agtcaattca gataggacct gcatacgggc
    11161 aaccgcacga gctgttacaa aatcatattg agcacggaag ttcttgtctt gggcaaaatc
    11221 ttcggcacgt ccgtggtaga aatgaactcc gttcaaatcc agttcttgag ccaagagttg
    11281 taggaagttg atgcgcttat tgagtgaatc aataatggtc acatctaact ccggatagag
    11341 aattttcatt ggtagactag gaaatcctgc cccagccccg atatcaagaa gtttgatagt
    11401 ttcattggga atcaaacctt gaagaatggg tgcaatcgaa tcgtaaaaat gtttgagata
    11461 aacttcttcc ttgtccgtaa tcgccgtcaa attaatcttc tcattccact cgaccaagag
    11521 ctcaaaataa cgttcaaatt gttctttttg ctggtccgaa agtggaagat tctgctcggc
    11581 aagcaagttg taaaatgttt ttggtttcat agttatttcc ttctttagta tcatcttatt
    11641 ttaccacaat catagaaaat ttgatatact ggtactaatc taaaagcaga aaggacttat
    11701 attatgactt ggattattct tggagtttta gctcttgttg ttatttttgt gattgttagc
    11761 tataacggtt tggttaaaaa tcgtatgcaa accaaggagg cttggagtca gattgatgtt
    11821 cagttgaaac gtcgaaatga cctcttgcca aacttgattg agactgtaaa aggttatgcc
    11881 aaatatgaag gttctaccct tgaaaaggtg gcagaactac gtaaccaagt ggcggcagcg
    11941 acttcaccag cagaagctat gaaagccagt gatgccctca ctcgtcaggt ttcaggtatt
    12001 tttgcagttg cagaaagcta tccagatttg aaagctagtg ctaactttgt taaattgcaa
    12061 gaggagttga caaacacaga aaataaaatt tcttactctc gtcaactcta taacagtgtt
    12121 gtcagcaact acaatgtaaa attagaaact ttcccgagca atattatcgc tggaatgttt
    12181 ggatttaaag cggcagattt ccttcaaaca cctgaagagg aaaagtcggt tcctaaagtt
    12241 gattttagcg gtttaggtga ctaagatgtt gtttgatcaa attgcaagca ataaacgaaa
    12301 aacctggatt ttgttgctgg tatttttcct actcttagct cttgttggtt atgcggttgg
    12361 ttatctcttt ataagatctg gacttggtgg tttggttatc gcactgatta tcggctttat
    12421 ctacgctttg tctatgattt ttcaatcgac agagattgtc atgtccatga atggagcgcg
    12481 tgaggtggat gagcaaacgg caccagacct ctaccatgta gtggaagata tggctctggt
    12541 cgctcagatt cctatgcccc gtgttttcat cattgatgat ccagccttaa atgcctttgc
    12601 gacaggttct aatcctcaaa atgcggctgt tgctgcgact tcaggtctac tagctatcat
    12661 gaatcgtgaa gaactagaag ctgttatggg acatgaagtc agtcatattc gtaattatga
    12721 tatccgtatt tcgactattg cagttgccct tgctagtgct atcaccatgc tttctagtat
    12781 ggcaggtcgt atgatgtggt ggggtggagc aggtcgcaga cgaagtgatg atgaccgaga
    12841 tggaaatggt cttgaaatca ttatgctagt ggtttcccta ctagctattg tactggcacc
    12901 tctcgctgca accttggttc agctcgctat ttctcgtcag agggaatttc tggcagatgc
    12961 atctagtgtc gagctgactc gcaatcccca gggaatgatt aatgccctag ataagttgga
    13021 caatagcaaa cctatgagtc gccacgtcga tgatgctagc agtgcccttt atatcaatga
    13081 tcccaagaaa ggtggggggt tccaaaaact cttttatacc cacccaccta tctcagaacg
    13141 gattgaacgt ttaaaacata tgtaaaatga aggctggaaa aaagtcttta aaatctgaaa
    13201 aacgcataat atcaggtgtg aaaacttgat attatgcgtt ttactatggg aagatttact
    13261 tctttttctc ctaaaattgt gtttttgccc cacctatctg ctatgttgca aatttataaa
    13321 tcttctaaat taactagctt caaaccgtgt tctgtcatgc gatagatgat cgagcagact
    13381 tcttttaaga aacgacggtc atgcgaaaca gtgatgagac cgccaggata agtggcaaag
    13441 agttttctga tttggggttg agaagtggga gaaaagtttc gtgtgggttc atccagcagg
    13501 agaaagtttg gtttgcgcag gactaaatcc aaaagcagga gttttccctg ttgtccgcca
    13561 gataaggagc gaatttgatg ctgcatttct ggataactga aattgagact agctaggtga
    13621 gattggattt tctgtagttc ctctttttcc ccagttttac tgagataggc tattggggat
    13681 aaatccaatt gcagtttttt gtggtaatct tgtggcataa aaccaagtga aatctctctt
    13741 ttatcattca gaagtctctg taacttggct aacagagttg atttcccaac accatttggc
    13801 ccgataatac cgattttttc ttggccacgg acagttagtt gtagtttttg aaccaaaact
    13861 cggtcgtcaa tggacaaatt ttctttttcc agttggacta agactttaga agctggtaat
    13921 ggttggatgt ctgaaaagaa aagttggatt tgttcctctt caagtggctt ttgagtcatg
    13981 gactgagctg ccttttcgta gcgtttttct tgtgagagga cagttttcat ctttttagcc
    14041 aataggcgac cggcagtact atctttggta gctcgaagcg cagtttctac actttgcttg
    14101 actctccgat gtttttccat ggttttatcg taggctcttt ggttgttagc agcttgctga
    14161 ctttgtttgg caaaattagc ctttctctgc tcactatagc tatcatagtc taaatgctct
    14221 actagcgttt ccgcttcttt acggtgtttg accagtcgca agtgaacaat agtgtctgcc
    14281 gtttcagaaa gaaagtcttc atcatgggaa atgaaaataa cggtttgcct ggtcttttga
    14341 atctggcctt ttagccaatc aactgtctca aggtctaggt catttgaagg ttcatctaaa
    14401 aatagaatct caaagggttt ggctaactca tggataagct gaattttcaa agcttcgccc
    14461 cctgatagat tgccaatctt ttggtcactt gcgaaacgat tgctatcaaa atgcaattcc
    14521 tccgccaaac gatagaggat actgtagtct aaatcaatag aatctaaaaa gaagtagtcg
    14581 tgtaaagttt tctttttcag ctcctcggga agtttttgag gaatgtaggc cagtgactga
    14641 tagtcagatt ggatgtttcc cttgatagtg aaatcagaca aagcttcccc cattaaaatt
    14701 ttaagtaagg ttgatttgcc atttccttct tcaccaataa tagcaacctt ttccccgtct
    14761 tggatggtca tgcttaggtc agatacaaga tctcgtaaat ctttgttttg tgtgatggtt
    14821 agatgattga tttttatcat atgatttccc tttctagaat gttcatagtg cataacaaaa
    14881 agctctactt tacctagtag agcccaaagt ctatgtcaaa aaaactctat taacatgcca
    14941 gaaaaagagc ataaaagagc acacaaaaag agacaaaaac aagatctact aaataaaggt
    15001 tctttatttg atagacttag ttgttcatgt ctcccttacc tccgagtatt agtatcttta
    15061 tattatacct ttaaggaaat tttgtcaaca gaaaactgga aattctatgc tctaaaatcc
    15121 aaaaacaggt ccatagagac ttagtacgtg tttgacatgc tcgtaatgga atttatcata
    15181 gtttcgccaa gcagtgcgtg cttgatcgtt tagttttagg ctacccagtc caatcagaag
    15241 actggtgggt tggtaaaatt tctcaagatc aattaagata ctgttgttca acttttccgt
    15301 tttttgagct cttgcatagt agtgtttagc agctcttgta gtcgaatatc atctgccgta
    15361 ccctgtttac agttttggta gcttttattt aacttggata ggagttgaat gagtttcttg
    15421 tcttccatgt gagcatcctc cttgatctga tgtactcttt ccctatagta tagcactaaa
    15481 aaacaaaact gtcatagtaa atatgttaaa attttgaatt ttaattacaa agtttggtgt
    15541 gctgatttgt agccttttca tggtataatc aagagagtaa atctttatgg aggaagtatg
    15601 aaattaaata ttcaagaaat tcgtaagcag tctgaaggtt tgaactttga acaaacgtta
    15661 gatttagttg atgacctgcg tgcacgtaat caagaaattt tagatgtaaa agatatcctt
    15721 gcagttggga aagtacaata tgaagaccgt atgtatttct tagattatca actatcttat
    15781 accattgttc ttgcttcgag tcgcagtatg gagccagttg agttagttga atcttatcca
    15841 gtcacggaag ttttcatgga aggcgcaact aaccatctaa atcaagaaat tttagatgat
    15901 gacttggtct tgcccatcga aaatgaggcg cttgaccttg ctgagagtgt atcagacaat
    15961 atcttgctaa acattcctat caaggtcttg acggctgaag aagaagctgg tcaaggattt
    16021 gtctcaggaa atgactggca aatcatgaca gaggaagaat accaagctca acaagcagta
    16081 aagaaagaag aaaacagtcc ttttgctggc ttacaaggac tatttgacgg agatgaataa
    16141 tggtcttgtc aaaaaaacga gcacgaaagg tgctagaaga aatcattgcc ctcttcccag
    16201 atgccaagct tagtcttgat tttaccaatc attttgaact cctggttgcg gtcatgttat
    16261 cagcccagac gacagatgca gcggtaaata aggccacacc aggtctcttt gttgcctttc
    16321 caacacccca agctatgtct gtagcgacag agagtgagat tgcttcacat atttctcgct
    16381 tgggattgta tcggaataaa gctaaattcc ttaaaaaatg tgcccaacag ttactagacg
    16441 attttgatgg tcaagtccct cagacacgtg aagaattgga gagtttggca ggtgttggtc
    16501 gcaagacagc caatgttgtc atgagtgtag gatttgggat tccagccttt gcagtggata
    16561 ctcatgtgga gcgtatttgc aaacaccacg atattgtcaa aaaatcagcg acgccacttg
    16621 aggtggaaaa gcgggtcatg gatatcttgc cgcctgagca gtggttagct gcccatcagg
    16681 ccatgattta ttttggaaga gccatttgcc atccaaaaaa tccagagtgt gaccagtacc
    16741 cacaattata tgattttagc aatttgtaag atgctacatt gaaacttttt gcttgatttt
    16801 aagcatgctt tgtgctatag taaatgataa ctaaatattc ctttaaacct gtcccgtgag
    16861 gcaggcaagg agcgcgataa agtagaaggg tgaagtctat actgtgtgca gtagggctcg
    16921 cttggctata aatttcaagt ctccttgttt aaggagactt ttctttttgg aggtttgtca
    16981 tgaaaacaaa agaagttgta gacgaattga ccgtcaaacg agcgattacg cgtattactt
    17041 atgagattat cgaacgcaac aaagatttga ataagatcgt cttggctggt attaaaactc
    17101 gtggtgtctt tattgcccac cgaatccaag aacgtttgaa gcagttagaa aatctttcag
    17161 ttcctgttgt ggaattggat actaaacctt tccgtgatga tgttaaaagt ggagaagata
    17221 cttctttggt ttctgtcgat gtgacagacc gcgaagttat cttggtggat gatgtgctct
    17281 atacaggtcg taccatccgt gctgctattg ataatattgt cggtcatggt cgtcctgcgc
    17341 gtgtgagttt agcagttcta gtcgatcgtg gacatagaga attgccaatc cgtccagatt
    17401 acgttggaaa aaatatccca accagtcgtt ctgaagaaat catcgtagag atgacagaac
    17461 ttgatgacca agacagagtt ctgattactg aagaagctta gaaagttaaa ggagtagcca
    17521 tgtcagaaaa tcaacaagca ttgaaccatg tggtgtccat ggaagacctc actgtcgatc
    17581 aagtaatgaa attgatcaag cgaggaattg agtttaaaaa tggagcccag cttccctatg
    17641 aagaccatcc gattgtttcc aatctcttct ttgaggattc tacacggaca cataagtcct
    17701 ttgaagtcgc agagattaaa cttggattgg aacgacttga ctttgatgtg aagactagtt
    17761 cggttaataa gggtgagaca ctttatgaca ccattttgac tctgtctgct ttaggagtgg
    17821 atgtctgtgt gattcgccat ccagaggtcg actactatag agaattgatt gctagtccaa
    17881 cgattacgac ttccatcatc aatggtggag atggttcggg ccaacaccct agccagagct
    17941 tgcttgattt gatgaccatt tatgaggaat ttggccactt tgagggtctt aaagttgcta
    18001 ttgcaggtga cttggaccac tcacgcgttg ccaaatccaa tatgcagatt ttgaaacgct
    18061 tgggatctga actctttttc gctggacctg aggaatggag aagtcaagag tttgcagact
    18121 atggacagtt tgtaaccatt gatgaaatca ttgatcaggt tgatgtcatg atgtttctcc
    18181 gtgtgcaaca cgaacgccat gatagtggag ctgtattttc aaaagaagac taccatgccc
    18241 aacatggctt gactcaagaa cgttacgatc gtttgaaaga aacagcaatc ctcatgcacc
    18301 cagctccaat caatcgtgat gtagaaatag cagaccactt ggttgaagca ccaaaatcac
    18361 ggattgtcca acaaatgacc aatggtgtct ttgttcgaat ggcaatctta gaatccgtac
    18421 tagcgagtag aaacgccaac taaaacacaa gacgttaaaa gacgccagtg agcgtccacg
    18481 agaggtgaaa atatgacaaa aagaattcta gtattagaag atggcacagt ttttgaaggc
    18541 aaggccttcg gagcagatat tgatgtaaca ggcgaaatcg tctttaatac agggatgacc
    18601 ggctaccaag aatccattac agaccagtct tataatggac aaatcttgac ctttacttat
    18661 cctttggtag gaaattatgg tattaatcgt gatgattatg aatccattat tccaacttgt
    18721 aagggagtcg ttgtttttga agaagcgcgt agagctagca actggcgcaa ccaaatgacc
    18781 ttggatgaat ttttgaaagc caagaaaatt ccagggattt caggaattga tacgcgtgct
    18841 cttaccaaga ttatccgtaa gcatggtact atgcgtgcaa ccttgaccca tgttggggac
    18901 agtatggacc atgtgacgga ccagctccaa gcaacagttt taccgacaga caatatcaaa
    18961 caggtttcta ctaaaacgtc ttatccagct ccaggagttg gtttgagcgt ggtgctagtg
    19021 gactttggtc tcaagcactc aatcctacgt gaactttcta aacgcaactg taacgtgaca
    19081 gttgttcctt attcgacaac ggctgaagaa attctccatc tcaatcctga cggagttatg
    19141 ttgtcaaatg gtccaggtaa cccagaagac gttccacaag cactcgacat gattcgcggt
    19201 gtacaaggaa aaattccaat ctttggtatt tgtatgggac accaactctt tgcaatggca
    19261 aacggggcta agacctataa gatgaagttt ggccaccgtg gattcaacca tgcggtacgt
    19321 gaaatcgcaa caggacgagt agacttcacc agccagaacc atggttatgc agtcagccgc
    19381 gaggatttgc cagagcactt gattattacc cacgaagaaa tcaatgacaa gtcagtggaa
    19441 ggtgtgcgcc acagatacca acctgctttc tctgttcaat accacccaga tgcagctcct
    19501 gggccacacg acgctagcta cctatttgac gagtttatcg agatgatgga agtttttaaa
    19561 caatcaaact aagaacgagt aaaagctcgt cggagaattt atgtaactga acacggacgg
    19621 aaagctcaga atgtagagaa accaacttgg attgtcaatc cttccttgat ttcctaaaat
    19681 tcaatcgctt tctattcgtc ctttgtatct tatttaatgt cgccctgaga ggcgacgaat
    19741 agaaaggaga agggtgctcc gtatttgctg aactgaatac gggctacgga cggtgctaaa
    19801 aagatagtta ttcctagaac tgacagttct tcgtcataac tcctatttta gctttgtccg
    19861 cttgacaccc ttaatatctt atatatgcct aaacgtactg atattcaaaa aattatggtg
    19921 attggttctg gtccgattat tattggtcag gctgctgagt ttgactacgc tgggactcag
    19981 gcttgcttgt cgttgaaaga ggaaggttat gaggttgttt tggttaactc aaatcctgca
    20041 accatcatga cggacaagga aattgctgac aaggtttaca ttgaaccgat tacacttgag
    20101 tttgtgacac gtattcttcg taaggaaggt ccagatgcct tgctaccaac actcggtggt
    20161 cagacaggtc tcaacatggc catggaatta tctaaaaatg gtatcctaga cgagcttggc
    20221 gttgaacttc tgggtaccaa attatctgcc attgaccaag cggaggaccg tgacctcttt
    20281 aaacaattga tggaagagct tgaacaaccc attccagaat ctgaaattgt taacacagta
    20341 gaagaagcag ttgcctttgc agcgacaatt ggctacccag tcatcgttcg tccagccttt
    20401 acccttggtg gtactggtgg tggtatgtgt gccaacgaga aagaattgcg tgaaatcact
    20461 gaaaatggtt tgaaattgtc acctgttacc caatgtttga ttgagcgttc gattgccggt
    20521 ttcaaggaaa ttgaatacga agtgatgcgt gactcagctg acaatgcctt ggttgtttgt
    20581 aacatggaaa actttgaccc agttgggatt cacacagggg attccattgt atttgcccct
    20641 gcgcaaacca tgtcagacta tgaaaaccaa atgcttcgtg atgcgagctt gagcattatt
    20701 cgtgccctca agattgaagg tggatgtaat gttcagctag ctcttgatcc taacagcttc
    20761 aagtattatg ttatcgaagt aaaccctcgt gtatcacgtt cgtcagccct tgcttctaaa
    20821 gcgacaggat atccgattgc taagttggct gccaagattg cagtaggttt gaccttggat
    20881 gaggttataa acccagttac aggttcaacc tatgccatgt ttgaaccagc ccttgactac
    20941 gtagttgcta agattccacg tttcccattt gacaagtttg aaaagggtga acgccgtctc
    21001 ggtacacaaa tgaaggcgac tggagaagtc atggcaatcg gtcgtaacat cgaggaatct
    21061 cttctcaagg cctgccgctc ccttgaaatt ggggtgcacc acaatgaaat acctgaactt
    21121 gcagcagttt ctgatgatgc cttgattgaa aaggttgtca aagcccaaga tgaccgtctc
    21181 ttctacgtat cagaagccat tcgtcgtggc tacacacctg aagaaattgc agagcttaca
    21241 aaaattgata tcttctatct tgataaactc ttgcatatct ttgaaattga gcaagaattg
    21301 ggtgctcatc cacaagattt agaagttttg aaaacagcca aacttaatgg tttttcagac
    21361 cgtaagattg ctgaactctg gggaacgact gatgataaag ttcgccaact tcgcttggaa
    21421 aacaagattg ttccagttta taagatggta gacacttgtg cggcagagtt cgactccgaa
    21481 acgccatatt tctattcaac ctatggttgg gaaaatgaat ctatcagatc tgataaagaa
    21541 tctgtacttg tcctaggttc aggtccaatc cgtatcggtc aaggggttga gtttgactac
    21601 gcaaccgttc actctgttaa ggctatccag gcagctggtt atgaagctat catcatgaac
    21661 tcaaacccag agaccgtttc aacagacttc tctgtatcag ataagcttta ctttgagcca
    21721 ttgacattcg aagatgttat gaacgtcatt gacttggaac aaccaaaggg agttatcgtt
    21781 cagttcggtg gtcaaacagc catcaacctt gcggagccat tggcaaaagc aggtgtgacc
    21841 atccttggta cacaggttgc tgacctagat cgtgccgaag accgtgacct cttcgagcaa
    21901 gctctcaaag aattggatat tccacagcca ccaggacaaa cggctaccaa tgaagaagaa
    21961 gcagctcttg cagctcgtaa gattggcttc ccagttcttg tccgcccatc ttatgtactt
    22021 ggtggacgtg ccatggaaat cgttgaaaac gaagaagacc ttagttctta catgcgaact
    22081 gctgttaagg ctagtccaga ccacccagtt cttgtcgact cttatatcgt tgggcaagag
    22141 tgcgaagttg atgccatttc agatggtaaa aatgtactca ttcctggtat catggagcat
    22201 atcgaacgtg ctggtgtcca ctcaggtgac tcaatggctg tttacccacc acaaaccttg
    22261 tcgcaaaagg ttcaggagac catcgcagac tacaccaaac gcttagcaat cggtcttcac
    22321 tgccttggaa tgatgaacat ccagtttgtt atcaaggatg aaaaagtcta cgttattgag
    22381 gtcaatccac gtgccagccg tactgttcca ttcctatcta aggtaaccaa tattcctatg
    22441 gctcaagtag cgaccaaact cattcttggt caaagtttat cagaacttgg ctaccaaaat
    22501 ggactttacc ctgaaagcac ccgtgttcat atcaaggcac ctgtcttctc ctttaccaaa
    22561 ctagctaagg tagacagctt gctcggtcct gaaatgaagt caacaggtga agttatgggt
    22621 tctgatgcta ctttggaaaa agctctctat aaagcctttg aagcttctta tctacacttg
    22681 ccaacttttg gtaatgtcgt ctttaccatc gctgatgatg ccaaagaaga agccttgaac
    22741 ttggctcgtc gtttccaaaa cattggttat ggaatccttg cgacagaagg gacagcagcc
    22801 ttctttgcta gtcatggctt gcaagcccaa cctgttggta agattggtga tgacgataag
    22861 gatatcccaa gttttgtacg caaaggaaga attcaagcta tcattaacac agtaggaaca
    22921 aaacgaactg ctgacgaaga tggtgagcaa attcgtcgtt cagccattga acacggggtg
    22981 cccctcttca cagcgctaga tacagctaat gccatgctta aggtacttga aagtcgtagc
    23041 tttgttacag aagcgattta aatagaaaaa ataagatata gcagcctgaa tttagaacag
    23101 tacacaggga t
//
LOCUS       DBJKQU010000029        21890 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.029, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000029 DBJKQU010000000
VERSION     DBJKQU010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21890
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.029"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(1..163)
                     /locus_tag="ACSUUC_001308"
                     /pseudo
     CDS             complement(1..163)
                     /locus_tag="ACSUUC_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(547..1743)
                     /gene="tuf"
                     /locus_tag="ACSUUC_001309"
     CDS             complement(547..1743)
                     /gene="tuf"
                     /locus_tag="ACSUUC_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HHQ8054513.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2654..3523)
                     /gene="gla"
                     /locus_tag="ACSUUC_001310"
     CDS             complement(2654..3523)
                     /gene="gla"
                     /locus_tag="ACSUUC_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HHQ8054514.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3746..4267)
                     /locus_tag="ACSUUC_001311"
     CDS             complement(3746..4267)
                     /locus_tag="ACSUUC_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mucin-binding protein"
                     /protein_id="HHQ8054515.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(4225..5331)
                     /locus_tag="ACSUUC_001312"
     CDS             complement(4225..5331)
                     /locus_tag="ACSUUC_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HHQ8054516.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5442..5696)
                     /locus_tag="ACSUUC_001313"
     CDS             complement(5442..5696)
                     /locus_tag="ACSUUC_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054517.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5690..5932)
                     /locus_tag="ACSUUC_001314"
     CDS             complement(5690..5932)
                     /locus_tag="ACSUUC_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054518.1"
                     /translation="MYQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     TLNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            complement(6054..6572)
                     /locus_tag="ACSUUC_001315"
                     /pseudo
     CDS             complement(6054..6572)
                     /locus_tag="ACSUUC_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_152639374.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6574..6900)
                     /locus_tag="ACSUUC_001316"
     CDS             complement(6574..6900)
                     /locus_tag="ACSUUC_001316"
                     /inference="COORDINATES: protein motif:HMM:NF013842.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HHQ8054519.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            7134..8852
                     /locus_tag="ACSUUC_001317"
     CDS             7134..8852
                     /locus_tag="ACSUUC_001317"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HHQ8054520.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAILVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8963..9310
                     /locus_tag="ACSUUC_001318"
     CDS             8963..9310
                     /locus_tag="ACSUUC_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HHQ8054521.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9588..10424)
                     /locus_tag="ACSUUC_001319"
     CDS             complement(9588..10424)
                     /locus_tag="ACSUUC_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HHQ8054522.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10437..11066)
                     /locus_tag="ACSUUC_001320"
     CDS             complement(10437..11066)
                     /locus_tag="ACSUUC_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054523.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11076..11717)
                     /locus_tag="ACSUUC_001321"
     CDS             complement(11076..11717)
                     /locus_tag="ACSUUC_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHQ8054524.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11863..13092)
                     /locus_tag="ACSUUC_001322"
     CDS             complement(11863..13092)
                     /locus_tag="ACSUUC_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HHQ8054525.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13082..14248)
                     /locus_tag="ACSUUC_001323"
     CDS             complement(13082..14248)
                     /locus_tag="ACSUUC_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HHQ8054526.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14392..15405
                     /locus_tag="ACSUUC_001324"
     CDS             14392..15405
                     /locus_tag="ACSUUC_001324"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HHQ8054527.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15450..15869)
                     /locus_tag="ACSUUC_001325"
     CDS             complement(15450..15869)
                     /locus_tag="ACSUUC_001325"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HHQ8054528.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15880..17286)
                     /gene="atpD"
                     /locus_tag="ACSUUC_001326"
     CDS             complement(15880..17286)
                     /gene="atpD"
                     /locus_tag="ACSUUC_001326"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HHQ8054529.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17372..18250)
                     /locus_tag="ACSUUC_001327"
     CDS             complement(17372..18250)
                     /locus_tag="ACSUUC_001327"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HHQ8054530.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18266..19771)
                     /gene="atpA"
                     /locus_tag="ACSUUC_001328"
     CDS             complement(18266..19771)
                     /gene="atpA"
                     /locus_tag="ACSUUC_001328"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HHQ8054531.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19786..20322)
                     /locus_tag="ACSUUC_001329"
     CDS             complement(19786..20322)
                     /locus_tag="ACSUUC_001329"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HHQ8054532.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20322..20816)
                     /gene="atpF"
                     /locus_tag="ACSUUC_001330"
     CDS             complement(20322..20816)
                     /gene="atpF"
                     /locus_tag="ACSUUC_001330"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HHQ8054533.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLADKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20830..21546)
                     /gene="atpB"
                     /locus_tag="ACSUUC_001331"
     CDS             complement(20830..21546)
                     /gene="atpB"
                     /locus_tag="ACSUUC_001331"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HHQ8054534.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21581..21781)
                     /locus_tag="ACSUUC_001332"
     CDS             complement(21581..21781)
                     /locus_tag="ACSUUC_001332"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HHQ8054535.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         6538 a         4708 c         3976 g         6668 t
ORIGIN      
        1 caaatcattg tttgattaca gtctaaaagt tctataatct ctttataaga tttgcccata
       61 tcagacgaaa tagaacgatt tgaagacgtt tatgatattt agctgtacga gagtctttta
      121 aaagtgtttt gatggtttgg atttcttctt taattgattt catattacta ttgtataatg
      181 ctttttgatt ttagtctagt attatactct tcgaaaatct cttcaaaccg cgtcagcttc
      241 gccttgtcgt atagatgtta ctgacttcgt cagttctatc tacaacctaa aaacagtgtt
      301 ttgagcagtc tgtagctaac tttctatagt aaaatgaaat aagaacaaga caaatcgatc
      361 aggacagtca aatcgatttc taacaatgtt ttagaagtaa atgtgtacta ttctagtttc
      421 aatatattat agtttgctct ttgattttca ttgagtatta gttcaatatc taaaaaaaga
      481 accttgccaa gcaagattct tttagtgtct gacttaaata attgttcttc tgggaactaa
      541 atcgaattaa gcttcgattt ctgtaaccat acctgaacca acagtacgtc caccctcacg
      601 gatagagaat gtagtacctt gttctacggc gattgggtga atcaactcaa cgtcgattgt
      661 cacgttatca ccaggcatta ccatttcagt acctgctgga agttcgattg aacctgtaac
      721 gtcagtagta cggaagtaga attgtggacg gtagttgttg aagaatggag tgtgacgtcc
      781 accttcttct ttagtaagga tgtagacttc acctttgaat ttagtgtgtg ggttgattga
      841 acctggttta gcgataactt gtccacgttc gatttcatca cgttgaacac cacgaagaag
      901 gacacctacg ttatctccag caagaccttc gtcaagttgt ttacggaaca tttcaacacc
      961 agtaacaact gctttttgag tttcttcttt gataccaacg atttcgattt cgtcgttgac
     1021 tttaacgata ccacggtcga tacgtcctga agcaactgta ccacgtccag tgattgagaa
     1081 tacgtcctcg actggaagaa gcaatggttt gtcagtgtca cgttctggtt ctgggatata
     1141 ctcatcaact gtgttcatca attccataac gatgtcttcg tatttagagt caccttcaag
     1201 agctttaagt gctgaacctt ggataactgg aagatcgtca cctgggaagt cgtattctga
     1261 caataggtca cggatttcca tttcaaccaa ttcaagcaat tcttcgtcgt caaccaagtc
     1321 aactttgttc atgaagacga taaggtgttt aacaccaacc tgacgtgaaa gaaggatgtg
     1381 ctcacgagtt tgtggcattg gtccgtcagt tgaagctact acaaggatag ctccgtccat
     1441 ttgagcagca ccagtgatca tgtttttaac gtagtccgcg tgtcctggag cgtcgatgtg
     1501 agcgtagtga cgtttttcag tttcgtactc aacgtgcgca gtgttgatag tgataccgcg
     1561 ttcgcgttct tctggagcag catcgataga cgcatagtct ttaggttggt taactgatga
     1621 aggcaagcga cgtgccaaaa cagttgtgat agctgcagtt agggtagttt taccgtggtc
     1681 aacgtgtccg atagtaccaa tgttaacgtg tggtttacta cgatcgtatt tttcttttgc
     1741 catttgagta aaagcctcca ataaaatata ttttatagat agacagtagg caatacagtc
     1801 taactttcct tactatttta tcaaatttca gctaaattgc aagtgtttta caacgttttt
     1861 gtgaattatt cttgataaaa atttaactaa ctaatagaaa gtactaaata gacttatcct
     1921 tcaaggagtt ttcagcatta tccatccact cacttgctga aaatgtaaac agtctctggt
     1981 ttatatagta aaatgaaaca agaatagggc aaatcgatca ggacagtcaa atcgatttct
     2041 aacaatgttt tagaagttga ggtgtactat tctagtttca atctactata caacctcaaa
     2101 actgtgtttt gaacaacctg cggctagctt cttagtttgc cctttgattt tcattgagta
     2161 taaaattgca gataaaacga taacaatcat aggactcagc agagtcaatg taggtcgaag
     2221 aatagccctc ctaatcgctt attttatagc aaaatgaaat agaaactgaa cattttgttg
     2281 aggaaggtaa atcaattcct cacaatgttt gagaaagaag ggaggactat tccaacttca
     2341 acccactata aagcagactt acaagatagg gaacccatct ccgataatat atagtagaat
     2401 gaaaactgca caatttgatt ggagaattca aaccaatttc taacaatgtt ttagaaacaa
     2461 gggtctatta tttcaactgc aacctactat agcccattga agctggaata gcccactgag
     2521 acttctaaac cactgctgga gaggagtttg tttagagttt ctttcatttc cctaaaaaat
     2581 caaaaagaga gaaccagtct gatcctctct tacttataga tggtgctcac tcaaatgtta
     2641 aaggagctat ttcttagaga taaaggaatt tgaatacagc tactgccgca attgctgctg
     2701 cgataggtgc tactactggt acccaagaat accaccattt tgaatcgcct ttatgctcac
     2761 caagaactga ttttggaagg aaagcatgaa ggagacgtgg tcccaagtca cgggctgggt
     2821 tcaaggcagg tcctgtaggt cctccaagtg atgttaccaa agccataacg aggaatccaa
     2881 gtgccaagtg agccacagaa agtcctgaag cagtgtgtgg agccacctgt gctttaatag
     2941 ccaagtcaga aaaatcaact gtttgtcctg cttctattgc cttttgtttc atgaattgaa
     3001 gcacttcagc accaaagaag tttttagtca aaccaagagc tgcaaagaac aaaacaaatg
     3061 aaccaacaaa ctcattaatc aaaccattga cagttgctgc atagcgactt tcttttgtac
     3121 catggtcaat acttgaaata gttgagaaag ttcccaagat gttatttggt ttttcagttt
     3181 tcaagtagaa tggacggtat gttgccacaa ctaaggcttg gccaaagata gcccccaaga
     3241 cttgcgcgat aatgtaaggt accacttgtg cccaagggaa aagaccgcta actgcaagcc
     3301 ctagagtgaa agcagggttg atgtgattcc cagatacgtt accaaacatc aaggctggga
     3361 tcataacccc cataccataa ccaacagcga tgacgatcca gccactttgg tgacctttcg
     3421 tacctttaag ttcaacgttg gcaactgcac cattcccaag aatgatcaaa atggcagttc
     3481 ccaaaaattc agtggcatac ttcagtgccc atgtgaaatc catttgctag attctcctta
     3541 aaatttttta gatattcctt attttatcaa tttttaccct atttagcaac tgatttctgg
     3601 aaatattttt aaaaaaatag gattcatagt ttcccagttc aacgtacttg taagcgtttt
     3661 tattcttcac gaaagacctc attctcaaaa ccaggaaaaa gcccacatct gtgatctttt
     3721 ccttgttcct agattctaaa atctattatt tttcatcttc ttttttcttg aagaatccta
     3781 atcctagacc agctaacaag gtcatgatac cagcactagc caaggtagca ttagcttctg
     3841 tacctgtgtt tggcaattcc tctctcttac ctgtctcata agtcggaact tctgggtctg
     3901 gattcactgg agtttcagtt tttggagtac ctgggtctgg agttggttta tctggtgttg
     3961 ataaacggtc ataccttacc gttatttctt tatcactaga gtctgacgta acttcttgtg
     4021 attcaactgt tggaatatct ggatctttgt acttgtcaat cttaccagat acaacctcgt
     4081 cccagtttcc tgttgtccat tcaccgtagg ttacaactcc cgtgaccttg ttctcagttt
     4141 ttgtacggct taaggttaca ggttgaacaa catcttcttt tacattttgg ttcgtaactt
     4201 tatcaacgta atgaatgata cgcgttatag tcttcgtctc agtagaggtt gctgttttgg
     4261 gaaccactgt ttcctcaaca ttctcacggt agtaatagtc aactgttgca ccgtcttctg
     4321 gtacgcattt gcaggagttg ctaccaaggt gtatgttgtt ttccttgtga taactcggtc
     4381 ttctttgtcc tcagttgttg ttttcccttc aatagttttt gattctgtgg tatactcaga
     4441 acctatcgct aaatcagctt ttataacaga ctctgccaac ttctcttggc taccttcttt
     4501 atagtaattg gctgttactg tagcagtggt tggcgcttcg ctttctctat aaactaaggt
     4561 cactgttcta ccttcgctta caatattccc agttaaactt gcagaatttg tatctgcttc
     4621 tttaaaagta taatattttc cgtcagtagt agtcatgcta ctgagttttt tatctgtgac
     4681 attgtagctg gtaccaatca gttgtttttt attggtaatg taggttccgt cactttcttt
     4741 ttctccaatt ccagtatcat ttttcaatga tagcaaacgc ccttgttcat caacatagcg
     4801 aactttcaca ttttctgaga ttagttctgc caattctgag gtttttttct ttttcttgat
     4861 ttcttcggtt attttccctt tctcttcttc gggaatattt agttttggaa tgattttttc
     4921 aacaacggtt cgtgatggtt ccacagtatc ttggatgact gaaaagtcag ctagaattgg
     4981 gagattatac tgaacacggt gactttgagt gtttactcct actctttcat tattctctga
     5041 aaatacttgt acggtataag aaacaacatc ttttcctaat agaacatccc cagtagagaa
     5101 atagccgcct tttcctagtt tgctatctcc agagtccact tctttcctaa tcttatcaga
     5161 tagtttttta ccagtcagta cattcgttcg cacaatccct ttgtctaccc ctacaaagtg
     5221 ggagaacttt ttgaactctt cagaaccaga tctagcccaa ccattattaa gggcatttgc
     5281 ttttgtattt gtattctctc tcaaaggttt ggcgattaga attatattca tcggcactta
     5341 gagttgctgc tatatctgac tcttgaatac caacttcctt actaccattt ctagcggcag
     5401 tatatgtgta tttatctgtt tctacttcta gctgattatc cttaacatga taggtaattt
     5461 tctcctggta taagagtctt cagtagttta tatgctctgt catcatcttt agctttagaa
     5521 gcagctgagt ttagccaagt tggggtatta ggagtatctt tatcagcctg tttcaagaca
     5581 ttattcaagt catttgctaa cctattggtt gtcctcactg tgaaagtttt cttccagtct
     5641 gaatcacttt tattagactt agatatgctc atgaaatcct ggtcaacatt caacacaata
     5701 tcgccttgtt ttttagcatc ttccgttgct tctgcttcaa attgatcatg gagtttttgt
     5761 tgctctggtg tatagttttt ttatttacac gatttaatgt actatttttt attttagtat
     5821 taagaactcc attaatacga tttttaaatt ctgcttcaaa aaatccctta atttgttggt
     5881 gcgcaagttc aacattcaaa cctttcttat acaagtcttc attctgatac aagtcttcat
     5941 tctgaacgat ttcggctaca cggtgaatgg tttgatcgta taccgtcttc tcttaaccag
     6001 cagtatcctt agttttaatg actactcgat aggttccttt agaaccgtta tagtcatcta
     6061 gttttaaaaa agcattccaa acattcaaaa atagttggaa cttcccttaa taaatccgtc
     6121 actttctttt tcaagatagc ccaagcttgc tcaataggat tcaaatccgg tgaataaggt
     6181 ggtagaggta agaaaaagtg tttatcttgg atgcagagtt catccaaaat gttcttggga
     6241 tgaaaactag cattgcccat gacaataaca tgaggtgtct tcaaagcagg taggagttgc
     6301 gttttgaacc actccacaaa gaaatcgctt gtcatgcttt tcttgtaaat catgggagct
     6361 ataaactctc cgtctacttg tcctgcaaca attgaagttc gctcaaaacg acgtccgcta
     6421 atcttttcat agactttctc ccctctagga gcccctgcat aaggacgata gaggtagcgg
     6481 tcgattcctg tttcatcaat atatacgatt ggtaaatctt ttaggttatc caaaatatca
     6541 agaaactcag cgactttctc tgactcttgt tccttaaaga tcgtcatctt tttttaaagt
     6601 gaccttaatc tgctttaaag ctgcccatac tgaaggaaca gcacaatcaa aatgtgccgc
     6661 aatttcccgt aaaaaagcat ctggatgagc ctctacaaag gctttcaatt cttctaaagg
     6721 gatcttacgc tttttgacga ctcgcttttt ccgctctaag ttcctttgtt cacgtctttc
     6781 ttttcccacg tgaagagagt tctgacgcca acaccaaaaa actttggccg cctcgacatg
     6841 tctgtgccct cctttgatgg aatctaatgc tccttgttta aaatcagtat tatatgccat
     6901 agctttatta gaccatgctt attttaaact aagcaactat atcaatgttt tgttatgaga
     6961 agacttactt tttttactga aattgaattt ttcctagcct caacatcata taaccccaaa
     7021 attcaatctg acctggtttg aagagatgtt cgaagcagat aaggttttac taaaactaaa
     7081 aaaaatgata taatcaaact gattaaatgt tttaaaaata aaggagaatt tgaatgtctt
     7141 accaagaaaa ttaccagaaa tgggttgatt ttgtggagct tcctgactac cttcgtcaag
     7201 atttggaaaa tatggacgaa aaaactaagg aagatgcctt ctatacaaat cttgaatttg
     7261 gtactgcagg tatgcgtggc ttggttggtg ctggtacaaa ccgtatcaac atctacgttg
     7321 ttcgccaagc tactgaagga ttggctcgtt tgattgagtc aaaaggtgga aacgagaaag
     7381 aacgcggtgt agcaattgcc tacgatagcc gtcacttctc acctgagttt gcctttgaat
     7441 ctgcggcagt tcttgctaaa cacggcatca aatcttacgt atttgaaagc cttcgtccga
     7501 ctccagaact atcatttgca gttcgtcatc tcaactgttt cgcaggtatc atggtcacag
     7561 ccagccacaa ccctgctcca tttaacggtt acaaggttta cggtgaagac ggtggacaaa
     7621 tgcctccaca cgatgcggac gctttgacta cttatatccg tgcaatcgaa aacccatttg
     7681 cagttgaagt tgctgatgtg gaaactgaaa aagcttctgg cttgattgaa gttatcggcg
     7741 aagctgttga cgtagaatac cttaaagagg ttaaggacgt aaacatcaac ccagccttga
     7801 ttgaagaatt tggtaaagac atgaagattg tctacacacc acttcatggt actggtgaaa
     7861 tgttggctcg tcgtgctctt gcccaagcag gatttgactc tgttcaagtt gttgaagcgc
     7921 aagcaactgc tgacccagac ttctcaactg taacatctcc aaacccagaa agccaagcag
     7981 cctttgccct tgctgaagaa cttggtcgtc aagttggtgc agatgttctt gtcgcaactg
     8041 acccagacgc tgaccgtgtt ggtgttgaag ttcttcaaaa agatggtagc tacctcaacc
     8101 tttcaggtaa ccaaatcggt gctatcatgg ctaaatacat cttggaagct cacaaaaacg
     8161 ctggaactct tcctgaaaat gccgctctct gcaaatctat cgtttcaact gacttggtaa
     8221 cgaagattgc tgaaagctac ggcgcaacta tgttcaacgt cttgacaggt ttcaaattta
     8281 tcgctgaaaa aatccaagaa ttcgaagaaa aacacaacca cacttacatg atgggatttg
     8341 aagaaagctt cggttacttg attaaaccat ttgtacgtga taaagatgcc atccaagcca
     8401 ttcttgtcgt tgctgaactt gctgcctact accgttctcg tggtttgaca cttgctgacg
     8461 gtatcgaaga aatctataaa gaatatggct actacgcaga aaaaacaatc tctgttactc
     8521 tttcaggtgt cgatggtgct gaacaaatca aagcgattat ggctaaattc cgcaacaatg
     8581 ctccaaaaga atggaacgca acagctatca ctgtcgtaga agacttcaag gcacaaactg
     8641 ctactgttgc tgacggtact gttacaaact tgacaactcc tccaagtgat gtgttgaaat
     8701 acacacttgc tgacggttca tggattgccg ttcgcccttc aggtacagaa ccaaaaatca
     8761 agttctacat tgcagttgta ggggaaacca acgaagaatc acaagctaag attgctaaca
     8821 tcgaagcaga aatcaatgca tttgtaaaat aaagacctat aaaagatgag accaaccaac
     8881 ctcatctttt ttcgtatcaa atctaagcaa ttttagaaac tttatggcat actagactta
     8941 tcaatgaaag cgaggtaatc tcatggaaca atttttagat aacatcaaag accttgaagt
     9001 cactacagtt gtgcgtgcgc aagaagctct tgataaaaaa gaaactgcaa ccttctttat
     9061 cggtcgcaaa acttgccctt actgccgtaa atttgcaggt acattgtcag gtgtcgtagc
     9121 tgaaaccaaa gctcacattt acttcatcaa tagtgaagaa ccaagccaac tcaatgattt
     9181 gcaagcattc cgctcacgct atggaatccc aactgtacca ggttttgttc atattacaga
     9241 tggacaaatc aacgtccgtt gcgactcttc aatgtcagca caagaaatca aagatttcgc
     9301 aggattgtaa aaaatcagct aacaagtctt aaaatcacaa aaacgcataa tgtaaggtgc
     9361 aaaaaccttg atattatgcg ttttattgtt cctaaaacag ttacatcagc atttcattac
     9421 agaacatttt aattttggaa gtcaaatcaa tttttaacaa tgttttagaa atcacagtgg
     9481 gctattccat attaaattat ccagattcaa tcgctattat cgttttccta gattacaaaa
     9541 aaactgcgtt ttgctaatca aaacgcagtc tcagccacta ttttatctta ctgtccttct
     9601 tttacttctt tggttgctac atcttctcca aaccattttt ggctgatttc ttggaacttg
     9661 ccgtccttgt aaagactaga aaaagcttca tttatcttct taaccaaggt tgtatcttcc
     9721 ttacgggctc caaccgcaaa agcttctgtt tctagtccaa ctgtaaagac attataatcg
     9781 tttaaaacac cttctgcttc taaataatag tttgcataga cacggtcaat caatagacca
     9841 tcaattcgat cgtttttcaa atcaatcaag gcttcattaa aggtttggta ttgattcgct
     9901 tccttattag cgacaatatt cttcaaaatt tctggatttg cttcaaagtc cgcataacca
     9961 gatgaaccag cttgagctcc taatgtcttt ccagtcatat cctttgcagt cgtgatacca
    10021 gatgatttct tcgtaaccaa tacctgctca ttcttcatat atgagttact gaaagccacc
    10081 ttttcacggc gttcgtctgt agcggaatag ccattccaaa tcagatcaat cgttcctttt
    10141 gtcaattcag cttctttcaa atcccaatca atcggttgcc aatttaccgt gattccgtat
    10201 ttttcaaaaa cagctgtagc taaatcaata tcaaatcctg cataagaacc atctttctga
    10261 gcaaatccca ttggaacaaa agtactatca aatccaatag taatagactt gttagactgg
    10321 tactttgacc aattatctcc actagtttcg ctagaatttt tcccacaagc tactaagaac
    10381 aaagcagtca tcagactgac taatacaagc atccattttt tcatccattt ttcctcctat
    10441 ttaggttcta ctttcaataa tacatctgcg atattttcag caaactgcaa atcatgggta
    10501 accacaatct gggtcatccc aagttcccta ttttgcaaga ttagcttctc cacttccaaa
    10561 cgtaattctg gatccagggc agaagttggt tcatcgtagc caatgatttc tgggtcaatc
    10621 atcatagcac gcgccaaagc cacccgctgc ttttgcccac cagatagtga gaaaggatag
    10681 gcctctgcgt gtcctcctag tcctaactgt tccaagagtc cactcgcctt cttctcagcc
    10741 tcttcctgct tcattcccat ggtcttcaca ggcgataagg tcaaattgtc cagaactgat
    10801 aaatgaggga acagttgaaa atcttggaat acaaatccca gtagattgcg cttctgcaat
    10861 tcatccagct ctaaaggttg tccattataa aagatttgcc ctgaatcaat ggtttcaaga
    10921 cctgcaagca tacgtaaaag agttgtctta cctccaccag aaggtccaac gatagccagg
    10981 atttgctttt caggaatact tagactgaaa ttagacagga tttgtttgtc tccaaagact
    11041 ttattgatat ttcgtaattc taacatggca gcctcctatc tataataact atacttcttc
    11101 tcaacttttt tggaaataat tgtcacaatc ccaatcaaaa tcaaataaat ggctcctgcc
    11161 aagaacatag gaactagact agcatcgcgg ttagcagctg ttcgactagc caagataagg
    11221 tctgaaattc cgagagcata gaccaaagaa gtatccttga ccaaactcat aacttcatta
    11281 aagacactag gaagaacgat cttggtcact tggggcaaga taatatagcg cactctgtca
    11341 aaagggctaa acttcaagac cttggcggcc tcatactgtc ctcttggaat agtgtcaatt
    11401 cccccacgga aaatttctgc aaagtaagct gcatagttga gaacaaaggc aataatagct
    11461 gcaggaaggc ggtctaaacg aatcccaata cttgggagca cataatagat aaaaatcagt
    11521 tgcaagagta agggggttcc tcgcataacc cagatgtaaa tgttaatcag ataatggagg
    11581 ggcttccaat ggacttgcaa ggcaaaggca atcaaaacgc ccaagggaat cgaaaatagc
    11641 aagaccagtg caaagacctg tacagtcgtg ctcgcaccat tcagtaaact cggtaatatc
    11701 tcaaataaat aagacatact gcacctccta aaagtaattg ttcctattat agcatgaata
    11761 aacaagatta ccaagtattt ttgtaaaaag attctaccat atacaaataa aaaccgtagc
    11821 tatcaaaaga gataaactac agttctatat gtttaaacat tcttacaatc tctcaaacag
    11881 ttcttgcatt tgcacatcat ctggaaccag ttttaagtaa gtgtgagcat ggacttttgc
    11941 ttcttcaaaa tgtcccaatt cacgcaagag atagatatag tgttccagaa attctggatt
    12001 gtccttcaaa tctcctatca actcttgata atgctcataa gcagtatcca aatcgtccat
    12061 ttcttgataa gaacgagcaa tcatccactt ggtcaaaaga ttttctgact cctcactctg
    12121 caagtctaga atatcctcat aacgctcctg ctccagataa atagtggcta aacgaagcaa
    12181 gatttcttct gtatcctcag cgtcttcttt tgcagtaagg agataatttt ctgcaccact
    12241 agcatcatgc aattcataag aaaattgtga agcagctagc aagaggcgag tttcaaaggg
    12301 atttttctct aatccttgct tagcgatacg cagggcttct tgaacttgat gttccttatg
    12361 taaagcctga ctgtacccat actcatagcc ttcaaagtca ggagaaatgg tatcaagctg
    12421 cttaaagtag agggtggctt tttgatattc ttcttgatca aaataaagac tggccaactc
    12481 aaaagctgtt aagtcatcgt attctaactc cagggctttt tctaaaaact cagtagccgt
    12541 ttcaaatttc cctaactgag cataggcaaa gccaattcgt tgataggtgg aaatgcccgt
    12601 ttgctcataa atcgagcgat tatctaactg ggcataggct tgaatagccg cttggtaatt
    12661 ttccaactca ctatccaact ctgccaaacc caatatcaag agagaatcct ctgagtaggt
    12721 caaggcctcc aataatttct cacgtgccac atctgtcaaa ccttccagct ggtaaaggtc
    12781 tgccttcaga gccaaagacg agacatacca gtcactgtca gcttggattt cctcaagata
    12841 ggtaaaggct tcttctattt gaccatcctc gctagcaatt gcagctagat taagatgaac
    12901 ctctggaaaa tcctctacaa ttttcaggta aatttccttg gcctgaggat agaaaccaat
    12961 cccttcaaga taagttgcca actcatacag aagatcactt gaatcatttt ctaaagcttt
    13021 ggcgaaataa tgctcagcct tagttaaatc ttgctcctcc aaagcctgta acatctgttg
    13081 actattgttc actcttgact tcctcaccct ctaattcata tagaccactg actaccttat
    13141 accattcgaa aatggctgaa atgacaacct tagcagaggc ataaaccgga ataccaagta
    13201 aaactcccca gataccaaac atagatcctg aagttaacaa aacaaagaga acattaatag
    13261 ggtggatgtt taattgactt cccaaaatca atggagagac aaaacggcct tcaatagttt
    13321 gttctacgat aaagacaatc actactttca aaagcatgac tggaccagca atcaaaccca
    13381 atactagagc aggaagcatg gctagaaagc taccaagata agggaccaga tttaaaatac
    13441 cagcagtaac ccccagcgta accgcatagc gtagaccaat aatcttgaag aagatgataa
    13501 acattactgc tacaataata gccactgtca cttgccctcg aacatagttg gacaactgtt
    13561 gattcacatc tgataaaact tgtccaacag gttccttcaa ttttcttgga atgaattggg
    13621 tcaaatagtt acgcaagcct ttcccatcac gcaagagata aaagagcatg aaaggaacga
    13681 taatcaaggc aacaatcact tgagaagctc cgctaataaa ggcactcacc cagttgactg
    13741 cctgagatga aaccttactt gccaaaactg tagcctggct agaaaaattg gtcaaaactt
    13801 gctctaattg aggtctgaaa tcatctggca ggtgctgggc taccaatcca ttaacaatcc
    13861 tatctatatc ttctaagtaa acaggaacgt ttcttgcaaa ggtcaaaacc tgacgttgca
    13921 gatttggaat ggcgactgcc aagccccaaa tgataaagag agcgatgata acaaagacaa
    13981 tagtgatagc tataacacga ttaaccttat gcttctccat ccaatcaaca ataggattca
    14041 acaaataata taacaaacca gacaaaatga ctggcaacat cacaactgct aaaaagtcta
    14101 aaacaggtga aaatagaaaa ctaatcttac ttaaaataaa aagattcagt cccaataata
    14161 aggttactaa aaataccgta attgccttgt tatctaaaaa ccacttgaaa aaccaagata
    14221 ggctaaaatg tttctctttt tgctccataa atacttcctt tctattgttc tctcattata
    14281 ccatttttga aacaaaataa ctctttttta aagtgcttac atctaattgg atatctttaa
    14341 tttacttgtt tttgtgatat aatagtctta tctttacaca gaggtatagt aatgaaagaa
    14401 actgtttatt ttggaactta tacacgtcgt acttctcaag ggatttacaa ggcagacttt
    14461 gatacagaaa ctggtcagct ttcaaatcta gaactttttg cagctgagcc aagtccaacc
    14521 taccttgcct ttgaccagca ccaacattta tacactgttg gtagccaaga cgataagggg
    14581 ggaattgcag cctatcaaac tgacgggact gtgttaaatc atgttgttga agaaggagct
    14641 ccccactgtt atgttgctgt cgatgaaaag cgtgatttgg tttacgcagc caactatcac
    14701 aagggacaag tccttgttta taaacgccag gaagatggta gtcttctact tagtgatatg
    14761 gatcaacaca gtggccaagg tccacatgaa aatcaagctt ccccccatgt tcactataca
    14821 gatttaacac ctgaccacta tctagtgacc tgcgacttgg gaactgacca agtcatcacc
    14881 tatgacctcg atcaagaagg aaaattatct aagctctata cctatcacag caagccagga
    14941 gcaggctcac gccatatcat tttccataac cactataaaa tcgcttatct catttgtgaa
    15001 ctcaatagta ctatcgaagt tttaatctac gatggcgttg gcgaatttga acgtatgcag
    15061 gtcatttcaa ctttaccgga agcttacgaa ggctttaatg gaaccgctgc tattcatctc
    15121 tctaaagacg gtaaatacct ctacgcttct aaccgtggcc atgattctat cgcagtatat
    15181 accatccttg cggacggtag cttagagtta ttagaaatcg ttccaacgca tggtcagact
    15241 ccacgtgatt ttgatttgac acccgaccaa aaatttctca ttgttgtcca tcaagactct
    15301 gacaatgcaa ctgtctttaa acgtaattgt gacaatggtc gtctagcaga actctccaac
    15361 gacttccatg ttcccgaagc agtctgcatc cgttttgctc cttaaaacac cataaaaaat
    15421 gaacttggta ttttcaagtt cattttttct tatagtctat ttccgacatt aatacggtta
    15481 atagcacgtt gcaaagcaat cttagcacga cgttcttggt caatcaaatg tttgtcttgt
    15541 gcttcttcaa ttgcacgttc tgcacgaagt ttggcacgtt ctgcacgact gatatcgata
    15601 tcacgagcac gttctgcaga gtcagcgacg attgtgatca tatcattggc aatttcaata
    15661 acaccaccgt ttactgcaat ccagttcacg tgatctttat catcgatacg ttttaccttt
    15721 acttcatcaa ctgctaaaac cgcaatcata ttttcatgtc gtggcaagat ccccatctca
    15781 ccatccagag ttcgaaccga tacatagctg gcatggtgat catagacgag accatctggt
    15841 gtcacgatct ggacagttaa ctgagccata gttcacctct taaaatccca ttttttcagc
    15901 ttttgcaatc acatcttcga tagaacctac accacggaag gcatcttctg gcaagtggtc
    15961 gtatttacca tcaaggattt ccttaaagcc acgtacagtt tcagcaactg gaacataaga
    16021 acctggctga ccagtaaatt gttccgcaac attgaagttt tgtgacaaga agaactggat
    16081 acgacgggcg cgagcaacca aggtcttttc ttcatcagaa agttcatcca taccaaggat
    16141 agcaatgata tcttgcaatt catggtaacg ttgaaggaca cgttttactt cagcagcaac
    16201 tgcatagtgc tcttctccaa cgatttcagg tgccaaggca cgtgagcttg aagcaagtgg
    16261 gtcaacggct gggtagatac ccaattgtac caacttacgt tccaagtttg ttgttgaatc
    16321 caagtgagcg aaggctgttg ctggcgctgg gtcagtatag tcatccgctg gcacatagat
    16381 agcctggata gaggttacag aacccttctt ggttgatgtg atacgttctt gcaattgacc
    16441 catttccgta gcaagtgttg gttggtaacc aacggctgat ggcatacgac ccaaaagggc
    16501 agatacttct gaaccagcct gagtgaaacg gaagatatta tcgataaaga gaagcacgtc
    16561 ttggccttcc acatcacgga agtattcagc gattgtcaaa ccagtaaggg caacacgcat
    16621 acgtgctcct ggtggctcat tcatctgacc aaagaccatg gctgttttct cgataacgcc
    16681 tgattctttc atttcccagt aaaggtcatt cccctcacga gtacgttccc caacaccagc
    16741 aaatactgaa ataccaccgt gctcttgggc aatgttgtga atcaattctt ggattaagac
    16801 agttttacca actccggcac caccgaaaag tccaacttta ccacctttaa ggtaaggggc
    16861 aagaaggtca ataaccttga tccctgtttc aaggatttca gaagaggtag acaactcatc
    16921 aaaagttgga gcttttttat gaattggctg acgctctgcg tcttctgtaa aaggagcttc
    16981 caagtcaatg gtatctccca aaacgttgaa gacacgtccc aaagtttctt tacctactgg
    17041 tacagagatt ggacgacctg tgtccaatac ttccattcca cgagtcaacc catctgttga
    17101 ttccatggcg atagtacgaa ccataccatc tcctaactcc aaggctactt caaggacgat
    17161 ttttgttttt ctttcgtcat ttttgtagac gacaagtgca ttgttaatct caggaagttt
    17221 ttcccctgct gcaaacaaaa cgtctacaac gggaccgata acctgagcaa ttttacctga
    17281 actcatctcc ttctcctatt ctatataaga tactgtcggt tcctagctca actaggtcct
    17341 aagttcattt tcatacgagc tggactagag cctattctaa ggcactagca cctgctacga
    17401 tttctgtaat ttcttgtgta atcgccgcct gtctggcacg gttatactga attgtcaaat
    17461 cattgatgac tttcttagca ttatctgtcg ctgtttgcat ggctgtcata cccgcagcat
    17521 tctcagctgt cttggcatct ataatggcac cgtaaatcat actttctgca aactgaggca
    17581 acaactgctc cagaatttct tctcggctgg tttccaattc aaaagtcaag ctgtactctt
    17641 catccgcttc atttggatcc aagtcaacaa tcggaagcat ttgttccaca cgcatttgac
    17701 tggttagcgt attgacatgg tggttgtagc aaacataaag ctcatcaaag agttcatttt
    17761 ggtacatttc aacagttttt gaaataatct tacgaacttg atcaaagcta ggttggtctg
    17821 ccaagccacg taattcataa agtggttgaa taccgcgagc cttaaagaaa tcagctccca
    17881 tcccaccgat acagatcatt tcaaaacctt taccgtctgg gtggtattct tctttcaact
    17941 ccataacagc tttcaaaata gaggaattat aacctccaac caaaccgcgg tctgaagtga
    18001 taacgatata gcctgtcttc ttcacagaac ggctaatcaa catcggatta gttgaagcac
    18061 cagctccatt accatgaagg atatctgtca aaagtttacg cactttctga gcgtaaactt
    18121 ggaagttgcg agcagcttct tcagagcgac ctagcttagc agccgatacc atttgcatgg
    18181 cattagtgat ttgactcgta ttttttgttg aggcgatttt tgttttaata tcatttagag
    18241 atactgccat ctgacacctc tattcttatt ggaagctaga ttgattgaga aactctgtaa
    18301 tcgcagcatc caagactgct tcttctggca agtcttttgt atcacgaatg gtttccaaaa
    18361 tctctggatg ttgagcatca aagaaggcat ggaactcttc ctcgaaacga acaatatcat
    18421 ctactggaac agtatccaag aaaccatgtg tcaaagcata aagaatggtt acttgtttct
    18481 caacaggtaa tggtttgtga acaggttgtt tcaagacctc aacggtacga cgtccacggt
    18541 tcaacttagc ctgtgttgct gcgtccaagt cagaaccaaa cttagtaaag gcttccaact
    18601 cacggtatga agcaaggtcg atacgaagtg taccagcaac cttcttcatg gctttgattt
    18661 gtgcagaacc acctacacga gatacagatg aacccgcatc gatggctgga cgaatacctg
    18721 cattgaagag gccatcgcca aggaagattt gtccatcagt gatagaaatc acgttggttg
    18781 cgatataggc tgagatatct cctgcttgtg tctcgataaa tggtagggct gtaattgatc
    18841 caccaccaag ttcatcagaa actttagctg agcgctcaag caaacggctg tggagataga
    18901 aaacatcccc tgggaaggct tcacgacctg gaggacgacg aagcaagagc gacagttcac
    18961 gataagctac cgcttgtttt gatagatcat cgtatacaat caaaacatgc ttaccttgat
    19021 acataaattc ttccgccata gcgaccccag tataaggagc taggaagagc aatggagatg
    19081 gttgtgaagc agaggctgtc acaacgattg tgtagtccaa ggcaccgtac tgacgaagtg
    19141 tttctacttg cgtacgaact gttgattctt tttgtccaat cgcgacgtag atacagatca
    19201 tatcttgatc tttttggttc aagattgtat caatcgcaat ggttgttttc cctgtctgac
    19261 ggtcaccgat aatcaactca cgttgaccac gaccaatcgg tacaagggcg tcaatagctt
    19321 tcaaaccagt ttgcaatggt tctgaaacag acttacgttg cataacacca ggagctggtg
    19381 cttctactgg acgagtttta tcagtgtgga tttctccaag accgtcaact ggacgaccaa
    19441 gcggatccac aacacgacca atcagacttt cacctacagg gacttccatg attttccctg
    19501 tacggcggat tgtatcgcct tcacggatat ctgtaaagtc acctaggatg ataataccaa
    19561 cgtctgttga ctccaagttt tgagccatac cataagagcc gttttcaaaa ttcaacaact
    19621 ctccactcat gacattttca aggccgtgag cacgcgcgat accgtccccg atataggtta
    19681 caacacctgt ttcagtcaca tcaaaattgg gtttgaaatt ttcaatttgt tgcttaatta
    19741 aagcgctgat ttcttgtgcg ttaattgcca aaagaacacc actttctatt tcaaattttc
    19801 tttaacaact ttaagttgtt gtttaatact cacatcaatt gtcttgtgat tggcaaaaat
    19861 gacaaaacca ccaatgagac tttcatcgat ttgttctttt acactcctta ctttcagaga
    19921 catttttttc tcaatcaaag ggagcaaacg agtcttctgt tcatcagtta gaggatgagc
    19981 agacgtaatc gtcacttcaa atcgatttgt ttctttttca agtcggttca agcaatctac
    20041 aagcacatca taaaaaagat ttgctctgtg attgtaggcc agaacctgga taaagttttg
    20101 taataaaggc gacacagaat cttggaaaaa agcaattgtt ttttccttat ccgactcgtc
    20161 tactgccact tgttttaaaa aagaaggcag acctgttttt tcaacaactt gcttgatttg
    20221 agtcaagtct gaaaagatac ggtcttcttc tcctttttca agtaccaatt ggacaaaagg
    20281 catgctgtat ttttcaatta cctttactgt tttcttgtcc attaagcttc tcctagctga
    20341 tcgatatact gatcaatgag tgctttatgg gcatgactgt caaggttttg tgagatgatt
    20401 ttatcagcta agctgatggt cagatctgcg acctcaccct taacactctg taaagcttct
    20461 actttatttt gagcaatttc ttgattggct ttttctttta agtgtcctgc ttctagttta
    20521 gcatctgcta agatattagc cttactttgc tcagctgttt cctttgcatt ttcaatgatt
    20581 gtcttagctt ctttacggct accagccaat tcatcttcgc gtttttgagc caatacttct
    20641 gctttttgac gggcttcttc agctctgtca atatctgaag caattttttc agctctttct
    20701 tcgaaaatgc ctgtaatatt agaccatgca aattttttaa tcaagactag caaaagaata
    20761 aaagagccag tgattaaaat aaaattacca attaattcac ctactgttac gtgcatcagt
    20821 tactcctttc tattcctctt caatattaat cttattccct aaatacacag atgtcaaaag
    20881 agtaaaaaca taagcttgga tgcaggaaat aaagacagaa aatgcagtcc aagccaaatt
    20941 agctccaaag gctactggat accaataaat agcttggtgg gaaagaagaa gtaacaaact
    21001 cgtcatgacc tctcctgcaa agatattccc aaaaatccgc aaagccaaag ataagaagtt
    21061 tgtaaattct tccaagatat tcatcggtat gacaaaaaca ggactcataa aagattttat
    21121 acttttttta aatccacgac gacgaacgct ttctatatgt gtcaacaaaa tgacaagaaa
    21181 agataaggtt aagtcatact gtaaattagc ggttggcgaa ctccaccagt tagtcccatc
    21241 gatcgtttga agctttgtca ttaagccaag gttattggca atcaccatga aaaggaataa
    21301 acaaaggaaa aagagtgaat aatctttcat gtagcgcgaa ccaatattag gttctgtaaa
    21361 tccaataaca aagtcataga catactcaag tacattttgc tttcctttgg gtttcaaggt
    21421 catattgcgg cttgcccaat aaataaagac aaaaataact cccacaatca acaaagtcat
    21481 ggctaacata gtcagattga agataacagg accaatagag atgattggat taatactttc
    21541 ttccatctaa aatcctccct tttcttctcg ttccatgtat ttatttgata ataaatgaga
    21601 agacaagagt tacaaagaaa gttccttcaa taaaggcaac acctaaaaac atcaaactac
    21661 gaaactcaga aagcatatct ggttggcgtg ctactgattt aaacagtcca ttcatcaata
    21721 aaccttcacc gacagatacg cccatacagg caatacataa gcctaaaaat gttaaattca
    21781 taacaaattc tcctttaaaa taaaatttac ttacttagtg tagtcctaaa atttaaattt
    21841 gtcaactttt aaccgctatt ggaagcgttt aataaaaatt atttccattt
//
LOCUS       DBJKQU010000030        21366 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.030, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000030 DBJKQU010000000
VERSION     DBJKQU010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21366
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.030"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(<1..277)
                     /locus_tag="ACSUUC_001333"
     CDS             complement(<1..277)
                     /locus_tag="ACSUUC_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054536.1"
                     /translation="MGGAYLSKSACQGICAALAMSPGTFIALTGAAVLTKKLINYIKV
                     GGLGGWLIGAAAGVLALIFLIKICVDTTIKVLLNRIFKASKVMKRRIF"
     gene            complement(316..654)
                     /locus_tag="ACSUUC_001334"
     CDS             complement(316..654)
                     /locus_tag="ACSUUC_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HHQ8054537.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKIKGTRITK"
     gene            1120..1983
                     /locus_tag="ACSUUC_001335"
     CDS             1120..1983
                     /locus_tag="ACSUUC_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHQ8054538.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRRIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKK
                     EVETHYQPKKL"
     gene            complement(2176..2382)
                     /locus_tag="ACSUUC_001336"
     CDS             complement(2176..2382)
                     /locus_tag="ACSUUC_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054539.1"
                     /translation="MKHFFAGIGEINFVSYLLYICVGIAPFFHVYIIGSEMNFVKIVL
                     SILGIIFVCILTIARIYRTFFYKE"
     gene            complement(2384..2764)
                     /locus_tag="ACSUUC_001337"
     CDS             complement(2384..2764)
                     /locus_tag="ACSUUC_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HHQ8054540.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVDL
                     AIYSGGATIYSADAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGVDWADGSLDGYIFA"
     gene            3517..3843
                     /locus_tag="ACSUUC_001338"
                     /pseudo
     CDS             3517..3843
                     /locus_tag="ACSUUC_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            complement(3895..4482)
                     /locus_tag="ACSUUC_001339"
     CDS             complement(3895..4482)
                     /locus_tag="ACSUUC_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HHQ8054541.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            4724..5395
                     /gene="sdaAB"
                     /locus_tag="ACSUUC_001340"
     CDS             4724..5395
                     /gene="sdaAB"
                     /locus_tag="ACSUUC_001340"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HHQ8054542.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDDAIEEIRKIPHLHN
                     VNFFK"
     gene            5404..6276
                     /gene="sdaAA"
                     /locus_tag="ACSUUC_001341"
     CDS             5404..6276
                     /gene="sdaAA"
                     /locus_tag="ACSUUC_001341"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HHQ8054543.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            6298..6930
                     /locus_tag="ACSUUC_001342"
     CDS             6298..6930
                     /locus_tag="ACSUUC_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHQ8054544.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(7188..9038)
                     /locus_tag="ACSUUC_001343"
     CDS             complement(7188..9038)
                     /locus_tag="ACSUUC_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HHQ8054545.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(9077..10237)
                     /locus_tag="ACSUUC_001344"
     CDS             complement(9077..10237)
                     /locus_tag="ACSUUC_001344"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHQ8054546.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNMLQ"
     gene            10295..11461
                     /locus_tag="ACSUUC_001345"
     CDS             10295..11461
                     /locus_tag="ACSUUC_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HHQ8054547.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            11600..11926
                     /locus_tag="ACSUUC_001346"
     CDS             11600..11926
                     /locus_tag="ACSUUC_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHQ8054548.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            11913..12505
                     /locus_tag="ACSUUC_001347"
                     /pseudo
     CDS             11913..12505
                     /locus_tag="ACSUUC_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
     gene            12498..13409
                     /locus_tag="ACSUUC_001348"
     CDS             12498..13409
                     /locus_tag="ACSUUC_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HHQ8054549.1"
                     /translation="MRKWTKGFLIFGVATTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSANHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            13472..14536
                     /locus_tag="ACSUUC_001349"
     CDS             13472..14536
                     /locus_tag="ACSUUC_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HHQ8054550.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEERAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIEAPEDSEARTGIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(14617..15468)
                     /locus_tag="ACSUUC_001350"
     CDS             complement(14617..15468)
                     /locus_tag="ACSUUC_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HHQ8054551.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDVPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILV
                     QDFKTLA"
     gene            complement(15590..16576)
                     /locus_tag="ACSUUC_001351"
     CDS             complement(15590..16576)
                     /locus_tag="ACSUUC_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HHQ8054552.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(16848..18323)
                     /locus_tag="ACSUUC_001352"
     CDS             complement(16848..18323)
                     /locus_tag="ACSUUC_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHQ8054553.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKSVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFTFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(18427..19350)
                     /locus_tag="ACSUUC_001353"
     CDS             complement(18427..19350)
                     /locus_tag="ACSUUC_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHQ8054554.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(19364..20293)
                     /locus_tag="ACSUUC_001354"
     CDS             complement(19364..20293)
                     /locus_tag="ACSUUC_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8054555.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(20612..20833)
                     /locus_tag="ACSUUC_001355"
     CDS             complement(20612..20833)
                     /locus_tag="ACSUUC_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054556.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQEELQKAVLF
                     LADEKGSEHTAAELIDNLKEVIAKLKANA"
     gene            complement(20787..21047)
                     /locus_tag="ACSUUC_001356"
     CDS             complement(20787..21047)
                     /locus_tag="ACSUUC_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054557.1"
                     /translation="MTGVSNPTTDSARLVLADSKKAFADDSLIEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            21127..21264
                     /locus_tag="ACSUUC_001357"
                     /pseudo
     CDS             21127..21264
                     /locus_tag="ACSUUC_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         6525 a         4556 c         3785 g         6500 t
ORIGIN      
        1 aaaatatcct ccttttcatt accttacttg ccttaaagat tctgtttaat agaaccttta
       61 tcgtagtatc tacacaaatt tttatcaaaa agataagagc caatacacct gctgctgcac
      121 caataagcca acctccaagg cctccaacct taatatagtt tattagtttt tttgttaaaa
      181 ctgcagctcc agtcaatgct ataaaagttc ctggactcat agctaaagct gcgcaaattc
      241 cttgacaagc actcttgctt aaataagccc cccccatcaa gatacatcat ctcctcttgc
      301 tcaagagcaa cataattatt tggtaatacg agttcccttt attttctcct ttatactatg
      361 taataccaca aaatgatttt gacctaaatc attcttaact tgaagaatcg caggaaatgt
      421 taattttgga gtcaaatctt ccagtgctac tcgaacagct tttactgtaa aattcaactt
      481 attcagacct gaaacaatac cactgacagt cgttccatac atgtctgtac caataatttc
      541 ccgaatcttc atgattgata gttccttttt gtaagataaa agaactgttg aaacaactgc
      601 cgcagcacaa tctgactgat catgttgcat cgtacaagga tattttttta acatagaaat
      661 actcaattct ttagaattaa tctaactttt ctttgatgtc acccaaacct caatcactgc
      721 ccagtagttc ttgaatcagt ttagtttcaa tcgtatcatt ctttgttctt gatatctttc
      781 caagcattgt agtacagcag atttttgtcc aaggactaag cctcctttaa caactcaagc
      841 tcccttacat tatatcgacc agccccatgg aaagattatg gccagactaa tcaatgatat
      901 catacatact agaatacaaa atattttttt attcatactt tttctcctat ctttattttc
      961 tacctacatc atacctctta ttaagctcat tttaaaatta cgttaacttt tttcacaaat
     1021 ttatttttac tttctttttt actttttaca ctgctatgat acaatatttt taacaagatt
     1081 ttattatttg ttaacttttt tcacagaaag gagaaaatca tgcgttatga tttcggaaag
     1141 gtctataaag aaatacgtga gtcaaagggg ctgacccaag aagaggtctg tgggggtgtt
     1201 ctctcaagaa ccagcttatc aaaaatcgaa agtggcaaga caaccccaaa atatgaaaat
     1261 atggaatttc ttctccgtca aatcaatatg agttttgaag agtttgaata tatctgtcaa
     1321 ctttatcaac caagtcaacg cacagagatt atgcaaacct atctcaatat gcgttccatt
     1381 atcgggacca gcgatcttgt caatttattt caaaaatgcc aagactacct caagacccac
     1441 cacgatctcc ctatagaaga aatcagagat atgcttgaag ttgtcattta tatccgtcaa
     1501 cacggggcag gggaactatc agatcacgca gaacaggttg tcaaaaaact ttggagaaga
     1561 attgaaaaac aagatacatg gtatgagagt gatctaaaaa tcctcaatac cattcttttc
     1621 agttttccca ttgaatacct ccatctcatc actggaaaaa tattgcaacg cctagaagtc
     1681 tataaaaact atcaacattt atatgacttg cgaatagcaa tcctgctcaa cctttccaca
     1741 ctctatctat acaatcaaga taaaaacatg tgtaagcaaa tctgctacac tttactggag
     1801 gacgccaaga ataagaaaag ctacgatagg cttgctatct gctatgtccg tattgggatt
     1861 tgtacagata atgctaaact tatccaaaaa ggtttctcac tcctagagct gaccgaggaa
     1921 acttctatgc tgtctcatct caaaaaagaa gtagagaccc attatcaacc aaagaaatta
     1981 taaaaaaagt cgagggagct cctcgacctt ttcatagaat cgccgaacga tttaacgaga
     2041 aagtatgact tttacgttta tcccaactca attatgacat ttttttcaaa agtcaatata
     2101 tctcactttt tcaacgacaa gaaagaggct gataatctac caacctcttg tttttaaata
     2161 catttcaagt ccaaactatt ctttatagaa aaaagtccta taaattcgag caatagttaa
     2221 aatacaaaca aatataattc ccaaaataga taacactatt ttcacaaaat tcatttcaga
     2281 acctattata tatacgtgaa aaaaaggggc tattcctaca catatataca ataaataact
     2341 tacaaagttt atttcaccaa ttcctgcaaa aaaatgtttc attttaagca aaaatataac
     2401 catctaagct accgtcagcc caatcaaccc catatgcgat tgctccacct agtgaaaatc
     2461 cagtaacagt tagtgcaacg tttagtgcag tattgactaa atggccagct gcactaccta
     2521 catgtttaat tattaaacta cgtaatgttc tcgtaatagc ccctctatta gctgagatag
     2581 ctttttttat cgcatcagca gaataaattg ttgcaccacc actatagatg gccaaatcta
     2641 catccagaac tgttgcaaaa ctacctctac tattccacca gttacgacca acaccacccc
     2701 catcaagata catcatctct tcttgctcaa gagcaacata attatttggt aatacgagtt
     2761 ccatttattt tctccttttt tattaagcat ggttaggatg gtttcctaac aagtgatcgc
     2821 aggctttgtt tagttaccta aattagactt ccttccttta tcttatttta aatatttaaa
     2881 accagttact gcttgaagct taacagttta cttaattcaa ataacagcta atcactgatt
     2941 ccctgatttt atcaaatata ctaataacaa caattgtgat acgatcatca ttataagaac
     3001 aacatttaac gaatcaaagt ttttccgaga taataataaa gcaacagcaa gcagtattat
     3061 tactaaagat tgaataacta ctattactct taacatttta tcctccacta acaactcaag
     3121 ctcccttaca ttatatcgac cagccccatg gaaagattat agctagacta atcaatgata
     3181 taatacatac tagaatacaa aatatttttt tattcatact ttttctccta tctttatttt
     3241 ctacctacat agtacctctt attaagctca ttttaaaatt acgttaactt ttttcacgaa
     3301 aaggagaaaa ttatgcgtta ttattatgga tagcgctttc aaatttttaa actcccatcc
     3361 catcctttta tctatataat aagtgaaaat ataataactg tcaagtaatc gaagtgaatt
     3421 ttataaaaaa aattacaagc caaatttgca aagtttacaa taagccgcta gggcaatcgt
     3481 ctatcagaat gtccgtttat ttgtcaataa tccgagaaaa tcttgcaacg cttagaagtc
     3541 tataaaaact atcaacattt atatgacttg cgaatagcaa tcctgctcaa cctttccaca
     3601 ctctatctat acaatcaaga taaaaacatg tgtaagcaaa tctgctacac tttactggag
     3661 gacgccaaga ataagaaaag ctacgatagg ctggctatct gctatgtccc tattgggatt
     3721 tgtacagacg attctaaact tatccaaaaa gggttctccc ttctggagct aaccgaggaa
     3781 acttctatgc tgtctcatct caaaaaagaa gtagagatct attaccaagc gaaggaaaga
     3841 taaaaaagcc gagggatttc ctcgactctt tacatattat ttgttcgtta gttcttaata
     3901 ccagccattg ttaagccaga agtttttagc agcagtccat gaaccgtaac gtcctgcaac
     3961 gtaggcatct gctacacgtt cttggttttc agctgagtag tcaccgttca ggtatgaatc
     4021 tgttaattgg taacgtccga tataacgtcc atttgtagct gtatagctac cacctgattc
     4081 tttttgagcg atccattctt tggcttctgc ttcagatccg cttacagttg aaacaactgt
     4141 ttcacttact actggagttt ctgctactgg agctgaaaca gtttcatctt gagcggctgg
     4201 tgccgcataa gtagctggcg ctggtgttgc aacaggcgct acagggccat cgataaccaa
     4261 ctcttgatca acataaatca aatgaatgtt atcaatgtgg ttgttttctg ccaatttttc
     4321 aactgttgtg ttgtgagttt cagcgatttc tgaaagtgta tcaccttctt taacagtgta
     4381 agttgatgat tcttgagcag atacaaatga tggagcaaat actgcaaaca aggcagctac
     4441 tcctgcaaga gttgctttaa tctttttagt tattgatttc atattcgaaa attctccttc
     4501 tttctatagt tctatcatac cctttaaata ttaccgtttc ttgacacttt tatgtagaaa
     4561 tattacaaaa ttatttttta tttccctaaa taaggtgttt tttgtcataa aagatactat
     4621 ttttatgcta tttgaggtat tagaaaggtt ttcatccaca attaaagcca agcccctcat
     4681 tctttgatat aatagagata agaattttta taaggggaaa ctgatgaaat cacttcgttt
     4741 tcaatctgtc tttgatatca tcggaccagt tatgattggc ccatctagta gccataccgc
     4801 tggtgctgtt cgtattggga agattgtctc ttccattttt gatgatactc cgacagaagt
     4861 tgaattccaa ctttttaact catttgccaa gacctatcgt ggtcacggaa cagacctagc
     4921 ccttgttgca ggtattttgg gaatggatac agatgatcct gaaattccaa atagtctgga
     4981 aattgcccac aagcgtggta tcaagattgt ctggaccatt cagaaagaca gcaatgcccc
     5041 tcaccctaac accactaaaa ttactgttaa aaatgcccac aagaccatca gcgtgactgg
     5101 tatttctatc ggtggaggaa atattcaggt aaccgaactc aatggttttg ccgtctctct
     5161 caatatgaat acaccgacta tcatcatcgt tcatcaagat attccaggta tgattgccct
     5221 tgttacagag gcgctttccc gctatggtat caatatcgcc cagatgaatg tcactcgtga
     5281 aaaagctggt gaaaaagcca ttatgattat cgaagttgac agtcgcaact gtgatgatgc
     5341 tatcgaagaa attcgaaaaa tccctcatct ccacaatgtc aatttcttta aataggagga
     5401 agcatgtttt attctatcaa agaattggtc gagcaagcag atctggactt tcaaggaaat
     5461 gtcgcagaac tcatgattac aacagagttt gaattgaccg gtcgcgaacg tgaagaagtc
     5521 ttccttctca tggaacgcaa tctggaagtt atgaaagcct ctgtccaact tggcctcaat
     5581 gaaaataaat ctcgtagtgg cctgacaggt ggagatgctg ccaaattgga tcactacatc
     5641 aaaaacgaaa aaactttatc agattacacg attctctctg ctgcccgaaa tgctatcgca
     5701 gtcaatgaac acaatgctaa aatgggcttg gtctgcgcta ctcctaccgc aggaagtgcc
     5761 ggttgtctcc cttccgttct cactgctgct attgaaaaat tagacctcag ccacgagcaa
     5821 caattggatt tcctctttgc tgctggtgcc tttggactag tcatcgcaaa caatgcctcc
     5881 atctcaggtg ctgagggtgg gtgtcaagct gaagttggtt cagcctctgc tatgagtgct
     5941 gccgccttga ctctggctgc aggtggaaca ccttatcagg ccagtcaagc tattgccttt
     6001 gtcattaaaa atatgctagg cctcatctgt gaccctgttg caggtttggt cgaagttccc
     6061 tgtgtcaaac gtaatgccat gggagctagc tttgctttca tcgcagcaga catggccttg
     6121 gcaggtatcg aatctaaaat ccctgtggat gaagtgatcg atgccatgta ccaagtagga
     6181 gcaagcatgc caactgcctt tcgtgaaaca gctgaaggtg gactcgctac cacccctact
     6241 ggtcgtcgcc tccaaaaaga gattttcgga gaataagctt atcaaatagg agaaaccatg
     6301 acctctatca cagcgatttt tttcgatttg gatggaaccc tcgttgatag ttctatcggg
     6361 attcacaatg cctttaccta tacctttaaa gagctggggg tgcctagccc tgatgccaaa
     6421 actattcgtg gttttatggg accacctctc gaaagtagtt ttgcgacctg cctgtccaaa
     6481 gaccaaattt ctgaagccat gcagatatat cgttcttact ataaggcaaa aggcatctat
     6541 gaagctcaac tctttcctca gattatagac ttgcttgagg agttatcgag cagttatcca
     6601 ctctacatca ccacgacaaa gaatacatct actgctcaag acatggccaa aaacttggaa
     6661 atccatcatt tctttgatgg tatttatggt tctagccctg aagcacccca taaggcagat
     6721 gtcattcacc aagccttaca gacacatcaa ctagcaccag aacaagccat catcatcgga
     6781 gataccaagt ttgatatgct gggagctcga gaaacaggta ttcagaaatt ggccgtcact
     6841 tggggatttg gagagcaagc agatctacta aactatcaac ctgattatat cgctcacaaa
     6901 cccttagaag ttttggcata ttttcaatag catagactgg gtaacaattc catttcagaa
     6961 gaaaatgaag taatactcaa tgaaaatcaa agagcaaact aggaaactag ctgcgggctg
     7021 ctctaaacac tgttttaagg ttgtggatag aactgacgaa gtcagtaacc atatacggca
     7081 aggcgacgtt gacgtggttt gaagagattt tcgaagagta taagtctcta cataataaaa
     7141 cgcatattac caaggttgtg taacttgata ctatgcgttt ttctttttta ttcaatgtgg
     7201 gttgtttgat tagcaaaggc gataatagct tgcttcaact catctccact gagagtgcgg
     7261 aactctccaa tcttttgatt gatggattct aaaggcatga cattaacctt accaacgaaa
     7321 atcttatcca taacttgatt atcaacaagt tcggttgata ccaagagttc ttcgtagagt
     7381 ttttcacctg ggcggattcc aacttcaacg attggaattt cactttcagt gtggccactt
     7441 agaagcacca tcttcttggc caagtcataa atcttgactg gtttgcccat atcaaggata
     7501 aagacttccc catctttggc ataagcacca gcatggataa ccagacggct agcttctgga
     7561 atggtcataa agtaacgggt catgcggaag tctgtcaccg ttacaggccc accttcagca
     7621 atctgacgtt caaagactgg aatgacacta ccacggctac caagaacatt cccaaaacga
     7681 actgcacagt aggttgattg gctacgttgg ttaaagccag tgacaatcaa ctccgccacg
     7741 cgcttggttg ctcccataac atttggtgga ttaactgcct tatctgtcga aatcataacc
     7801 atcttagaca ctttagcttc atcaacagcc ttagcaacat tgtaagttcc acggatattg
     7861 tttttgaagg cttcttttgg attgcgctcc atcataggaa catgcttgtg ggctgccgca
     7921 tgataaacaa tagcaggttt gtactgctca aagacttgca acaaacgatc atagtcttga
     7981 atgtccgcaa tcacaggtac ataatcaatc ccttggaact tacgaatcaa ttcatgataa
     8041 acaaggtaga ttgagttttc cccatgaccg agcaagacaa tgcgttcagg attgaagcga
     8101 ctaacttgac gacagatttc agaaccgatt gaacctccag ctcctgtgac taagatggtc
     8161 ttacctgtca gttctgcacc cagacgcgat tcgtcaagac ggatttcctg acgacccaaa
     8221 aggtccgtaa tatcaatttt ttggaagcca gtacctgctt ggtgaaggcc ctgaacaaca
     8281 gtttcaacct taggcatctt gtaacatttg acacccagct tattacacat ctgcaagata
     8341 cgctcatatt ctgacggatc cagcgacgga atcgcaacga tgacacgctc gatttgatgg
     8401 cgtttggcta attcaggcag attgtcataa gagcccaaaa caggaatacc accaagtttt
     8461 tgaccctttt tcttagaatc cttatccaaa ataccgacca gttctaattc actggttgga
     8521 tgttggtaac tatccataaa gagagcccca ccatcaccgg caccaatcaa gaaggtccga
     8581 cggtgttctc catcaccact accttttttg cgtctggagt agattaactg ccaagtaatc
     8641 cgtggcaata aaatcaagaa ggtactcaac aagataaaga gaatgatgaa acggatggag
     8701 aagagtggca agaaggcata acagatacta tatgacaaga cactgctagc agtcacacca
     8761 aaaaagattt tcatgaaatc cgtaatcttg ctgtaacgac taatgctcgc gttcaatccc
     8821 caaaaaccaa tcatcaattg atagaacagg aaggccaaac tcgtatagat aatgtagtca
     8881 acaggtgctg gattaatcag cccataaaat aaaatataag atacaattat ggaaaccacc
     8941 atactgaaaa tatcaaatat tccccagaaa acctgctttt gttgtttatt taaaatttcc
     9001 accagatcaa tcacataatc tgttagtttt ttattcatag aaatctactc ctccttaaaa
     9061 gagttttact atattgttat tgtagcatat tttgatttat ttggcttatt ttatccaaat
     9121 aaattattgt tcccttgtac tccttcttcc atttaaatcc tctaattaaa cctacaatcg
     9181 tcccaaagcc ataagcaaag tgaatggaaa ataaaagaaa gggcatcaca attagaaatc
     9241 catttttatg ttttaataaa gtcagcaaag tgagtagtga caaaagtaga aaataggcac
     9301 ctaatagtaa agttatgaat acgaatgtga tcggtaacaa tgctagacta aacacaagac
     9361 tcaaaacaaa taaacaagga acatagtgaa ataatgataa acacttaaac tgaacatgac
     9421 ttgtcaagcc aatccacaaa ccatttaaat acttttgatg cagcattttc ttgaatgttg
     9481 gtcgaatata ctgataagat agaatacttg ggctatagcg gattttatat ccatattctc
     9541 gaattctata atgaatatca ttatcttcag ttcggccaag ttgctcattt actaaaccaa
     9601 ccttctggaa aacctctcgt ttatacattc catgaaaaat agaagaaaca tatctatcct
     9661 cagaactatt tcgataattg gcaatgctac tgccaaacat attttcctca acaagatgca
     9721 aggtctctgc ccattttcct tttccttcga caatcgtcgg tctaggcccc ccacagacaa
     9781 attcaccttg ttgaataata gccacattgt tcattacaaa agtctcagta acttttgaat
     9841 gagcatcaat ttttaaaata aggtccccta cagaatgttt aactcccagg ttaaaaccac
     9901 tagcttgatt tttcttagga ttgttataca atctaattga gttaaactct gtatcttcct
     9961 ttataaattg ctgaatgata gctgtggtcc catctgtgga catagcattt ataaatagaa
    10021 tttcaatatt ctctttagga taggtttgat tttttaagtc ttcaattaga ccaggcagat
    10081 atttttcttc attgtatgca ctgattacaa tggatacgag aagactttca acattttgag
    10141 tcactactac tctcctgaat ttttccttcc accattctat cataattttc aagactttcc
    10201 catttttatc ttgaaagcca gaaaccttac ttgacattat agtgaaaaag ccttaaaata
    10261 agctgttatt aaaatcagct agaagaggta ttatatgaaa aagcaatcac tcttttttgt
    10321 tccaggtatt atcctgattg gtgtttcctt gcgaactcct tttactgttt tacccattat
    10381 tttgggaaat atttcgcaag gtctggaggt agaagttagt tcgcttggtg tcttgaccag
    10441 cctgcctctc cttatgttta ccctcttttc accattttct acccaactgg ctcagaaaat
    10501 cggcttggag catctcttca cctacagcct cttcttcttg accatcggct cacttattcg
    10561 actaatcaat ctgcccctgc tctatctagg aaccttgatg gttggggcaa gtgtcgcagt
    10621 catcaatgtc ctgcttccta gtcttatcca agccaatcaa ccaaagaaaa ttggttttct
    10681 gaccacctta tatgtaacgt ctatggggat tgcaacggct ctggcttcct atctagctgt
    10741 gcccattaca caagccagtt cttggaaagg acttatcctt ctcctcacgt tactctgtct
    10801 agcaactttt ttggtctggc tcccaaatca ccgctataat catagactag ctccacaaac
    10861 caaacaaaaa agtcaaataa aggtcatgcg taataaacag gtttgggcaa ttattatctt
    10921 ttcaggtttt caatccttga tcttttacac cgtcatgacc tggttaccta ccatgtctat
    10981 ccatgcaggt ctatccagtc acgaagctgg cttgctgact tctatcttat ctctgattag
    11041 cattcctttt tcaatgacca tcccaagcct gacaaccagt ttatctactc gcaaccgtca
    11101 gctcatgctc actctggttt cactagctgg tgtggtcggc atttccatgc tctttttccc
    11161 aatcaataat ttcatttact ggcttgccat ccatctcctc atcggaaccg caaccagtgc
    11221 cctcttccct tatctcatgg tcaacttttc actcaagaca agcgcccctg aaaagacagc
    11281 ccaattgtcc ggcctatctc aaacaggagg ctatatccta gcagcctttg ggccaaccct
    11341 ctttggttac agttttgacc tgttccactc ttgggtacca tctgtagctg ccctcttgct
    11401 catcgatatc ctgatgactg tggccctctt tacagtggac agagcggata agatccttta
    11461 aacttctagt tttagctaga agttttttat atataaaaat tttacacatt tctcttgaca
    11521 gggctttctt ttagatgtac aatgtatgtg tagaaaaatt atatataaaa atcttacaca
    11581 ttagaaaagg aggtttccca tgtactttcc aacatcctct gccttgattg aatttctcat
    11641 cttggctgta ctggagcagg gtgattctta tggttatgag attagccaaa ccattaagct
    11701 gatcgctaat atcaaagaat ccacactcta tcccattctc aaaaaattgg aaggcaatag
    11761 ctttctgaca acctattcta gagagttcca aggtcgcatg cgcaaatact actccttgac
    11821 aaacggtggt atagagcagc tcttgaccct aaaagatgaa tgggcactct atacagacac
    11881 catcaatggc atcatagaag ggagtatccg ccatgacaag aactgaatac ctgactcagc
    11941 tagaactcta tctcaagaaa ctacctgaag ctgaccgtat cgaagccatg gactatttca
    12001 gagagctctt tgacgatgct ggagtcgaag gagaagaaga actcatcgct agtttgggaa
    12061 ctcccaaaga agcggcccac gaagttctat ccaatcttct cgataaaaaa tcaatgaagc
    12121 acccgctcaa aaaaataacc gacaaatttt acatatcgcc ttgttagccc tccttgcagc
    12181 acctatcggc attcctctgg gaattgccat cctcgtgacc ctgttcgcaa ttcttgtagc
    12241 cgctttgact gtcattctgg ctttctttgc agtttccata ctgggtatca tcggcggatt
    12301 cctattttta gttgaaagtt tcactgtcct cgcccaagcc aaatcagcct ttatcttgat
    12361 ttttggttct ggtttactgg ctatcggtgc ttcttcgcta gttttacttg gcatttccta
    12421 tgtaactcgc ttcttcggtc tactcattgt tcgtctggta caatttgttc ttaaaaaagg
    12481 aaagagaggt aatcagcatg cgtaaatgga caaaaggatt tctcatcttt ggtgtggcga
    12541 ctaccgttat cggctttatc ctgctttttg taggtatcca atctgacggg attaagagcc
    12601 tactttccat gtccaaagaa cctgtctatg atagccgtac ggaaaagcta acctttggca
    12661 aggaagtcga aaacctagaa attactctcc accaacacgc gctcaccatc acagactctt
    12721 tcgatgatca aatccacatt tcttaccatc catctctttc tgctaaccat gatcttatca
    12781 caaatcaaaa cgatagaact ctgagtctca ctgataagaa actgtctgaa actccgtttc
    12841 tctcttctgg aattggtggg attcttcata tcgcaagtag ctactctagt cgttttgaag
    12901 aagttattct ccagctacca aaagggagaa ctctaaaagg gatcaacatc tcagccaatc
    12961 gcggacaaac caccatcata aatgctagcc ttgaaaatgc gaccctcaat acaaacagct
    13021 atatcctccg aattgaagga agtcgtatca aaaacagtaa actcacaacg cccaatatcg
    13081 ttaatatctt tgatacagtt cttacagata gtcagctaga gtcaacagag aatcacttcc
    13141 acgctgaaaa tatccaagtc catggcaagg ttgaactgac tgccaaagat tatctcagaa
    13201 tcatcctaga ccagaaagaa agccaacgaa ttaactggga catctcaagc aactatggtt
    13261 ctatcttcca attcacaaga gaaaagcctg aatcaagagg tacggaatta agcaaccctt
    13321 acaaaactga aaaaaccgat gtcaaggatc aactcattgc gagatctgat gataatattg
    13381 atctaatatc cacaccaagc agacgttgac aaaaacgctt acatttgcta ctatggaaac
    13441 atatttatct aactaaaaag gaggttctac catgaaacaa gaatggtttg aaagtaatga
    13501 ttttgtaaaa acaacaagca agaacaagcc tgaagagcga gctcaagagg ttgcagacaa
    13561 ggctgaagaa acgatagcca atctcgatac accaattgga aaaaatactc aagtagagga
    13621 ggaagtctct caagctgaag tcgaactgga aagccaacaa gaagagaaaa ttgaagctcc
    13681 tgaagacagt gaagcgagaa caggaataga agaaaagaag gcatctaatt ctactgaaga
    13741 agagccagac ctttctaaag aaacagaaaa agtcactata gctgaagaga gccaagaagc
    13801 tcttcctcag caaaaagcaa ccacgaaaga gccacttctt atcagtaaat ctttagaaag
    13861 tccttatatc cccgaccaag ctccaaaatc tagggataaa tggaaagagc aagtgcttga
    13921 tttttggtct tggctagtgg aagcgatcaa atctcctaca agtaagttgg aaacaagtat
    13981 cacacacagt tacacagcct ttctcttgct cattctgttt tctgcatctt cctttttctt
    14041 tagtatctat cacatcaaac atgcttacta tggacatata gcaagcatta acagtcgctt
    14101 ccctgagcag ctagctcctt taactctttt ttctatcgtc tctatcctag tagcgacaac
    14161 actcttcttc ttttcattcc tcttgggtag tttcgttgtg agacgattta tccaccagga
    14221 aaaggactgg acgctagaca aggttctcca acaatatagt caactcttgg caattccaat
    14281 cttcctcact gctattgcta gtttctttgc tttctttgat agcctacgat ttacagccct
    14341 cttgtgtgtg attagcattg gaatcattct gcttgccagt ctccatatca ttacaagacc
    14401 aagtcaagca agtgaaaccg actccttcta tcaattattc ttgtctgtcc ttgtgaacgg
    14461 agttattatc ctcctcttct ttgtagctga agtggcactg attggagatt atcttcgtat
    14521 cttggccttt ctttaaaatt caatcctgtc attcttggca ggattttttc tatgtcaaaa
    14581 aagcaagtcg attgacctgc ttctgcttta cttttcttat gctaatgttt taaaatcttg
    14641 tactaggatg ggttgtattt ctatttgatt ggcgtctagc tggtggtaaa aagatggggg
    14701 taacacctct aagaattttg catagtccaa gcgagctatg gattcatagt cttctggttt
    14761 agagccgtct cctgtgattt gaaccaagtc aatctcccac tggacttcct tatccaccaa
    14821 ttgctcaata taggctgcag gaacaaacgg ttctctcggt aaaactgtct tgactccttg
    14881 agctagatgg taaacgccat gcacttttcc ttctccatcc tgatagaagg aaactctcgc
    14941 aaagtaggca tctgtctctt gaaccgcacg cacacgcgct tcaaactgag ccaagccatc
    15001 tgcctctaaa aagcttttca agttctcacg actaaagaaa ataggattaa aaattccttg
    15061 gcaaatcgta aaacgagcta cagggtctgc tagataggct tgaatacttg cttggaaata
    15121 agcttcaaaa tcaaaaccat ctagtccttc aatatcagtc cctgtataag caagcaaagc
    15181 atctaaaaat gacttgataa tctgccagtc tgtctttgtt agtaggtcag gaacatcgac
    15241 acgataagcc ttttgaccat cagcataact gaccttaaag agaaattgtg attgccccac
    15301 tatcgcacac tcgatatatt cgagacgatt aagaggctga cggagataga ctacatcata
    15361 gctatgtgac tccaaaccgt ctagcaaggc caagatcgac ttggcattca aaatctcttg
    15421 ttctcctaaa atgctctgtt tatttggaat aaaaaatgtt ttcgccataa ctggactcct
    15481 ttgaaatcgt ttacatacag tataccttat ttttctgaaa gatacaaaaa caaactttag
    15541 atttttgagt acaaagcata gaaaaacagc ccctgaggac tgtttgatct tatacagtag
    15601 ctgcttgatc caagctttca ccgatagcgg ctaggcgctc gatcacttca gcttgtgtca
    15661 attcattttt tgaaacatag cggttacgtg ggtgaacacg gcactcgtgt gagcatccac
    15721 gaaggtactt gtcttcattt tcttctgatg tcaagatacg acggttacag aagggatttc
    15781 cacagttgac ataacgttca catggtgttc catcaaacca gtctttccct acgatagttg
    15841 ggttgacatg gttgacatca acggcaatac gctcgtcaaa gacgtacatt ttcccatccc
    15901 aaagctcacc ttgaacttct gggtctttac cgtaagttgc gattcctccg tgcaattggc
    15961 cgacatcttt gtaaccttca cgaaccatcc agcctgagaa tttctcacag cgaacgccac
    16021 ctgtacagta aaccacgaca cgcttgtcca tgaatttttc cttgttatca cggacccatt
    16081 gtggtaactc acggaagttg cgaatatctg ggcgaatagc cccacggaaa tgtcctaggt
    16141 catactcata atcattacgt gtgtcaagga caacggtatc tttatcaaga agcgcttctt
    16201 tgaactcttt tggagacaag taagcacctg ttgtttcaag tgggttgatg tcattgtcaa
    16261 agtcgttgtc ttccaaacca aggtggacaa tttctttctt gtagcgaaca aacatcttct
    16321 tgaaggcttg ttcactttct tcgtcaatct tgaaccagag ttcttccatt cctggaaggc
    16381 tgtgaacgta gtccatgtat ttttgagttg tttcatagtc acctgaaact gttccgttaa
    16441 ttccctcgtc agcgactagg atacgtcctt taagaccgat tgatttacag aaagccaagt
    16501 ggtctgcagc aaattgctct gcattttcaa ttggagtata aaggtagtaa agtaagacac
    16561 gaatatcttt tgccataaga tttgttctct tttctattct taaattttct aaatttttta
    16621 tttatctaca ctagtatacc tgcttgagaa aacgaatgca atttatttga ctggaaattg
    16681 tagaggggtc tcgaaatttc ctgaatggtt aaaataagga caagagaaaa catggatatc
    16741 tatatccttg tgccaaaaaa accactgtct cccccagacc aacctgagga aagcagtgat
    16801 tcttatttta ggagttagga atgaatacac gaaatcaatt tagctgatta ttttttgttt
    16861 ttcaagaatt catcgtattg tttttgcatt tcgttcaata ctttttcgta ggcaccttca
    16921 gatttcaatt tttccatcaa ttctggaatc gctttatctg ggtctacagt accagtgttg
    16981 atagctgtat caaattgttg cattgtgtta gcaatagctg agatttcaga tttcacattg
    17041 tcagtattga agataaatcc aagcgctgga gattctttag cttctgccaa ttctttctta
    17101 gaattttcga tttgttggtc tgtaacgttt tcgttgatgt aaaggatcca gttgttacca
    17161 gtgttccatc cacccatgtg agtgtttcct ttgtagccat caagaacgcg aacacggttt
    17221 tctttacctt caattttttc ccagttcttg ccttctggac cgtaaacaag accgttcaag
    17281 agttctgggt tcgtattcaa gaggttcaag atttccattg atttttcttt gttcttagag
    17341 ttgtttgaga tgacaaagtt agcaacttgt gttgtttggt ttttcttgat gaagttagta
    17401 attggtttga tttggatatc tttgttggca acacgtgaaa gcaagctgtt accgtagtca
    17461 gctggtccta ctgtttcttc acgaacgaac caagtatctt gttgaaggtc aaatgaagtg
    17521 tcacttgttg cgacgtcttt tggaatgtag ccagcttcat agaatttgtg aagagtcttc
    17581 aagtgttctt tgaaacgagg cacttcgtaa cggtttacaa ctttagtagt atcgccttca
    17641 aggtcaataa cgaatggaag cccgtttgct actgggtagt caaagttatc agatgggatg
    17701 aaaactttac caatagcaaa tggtactacg tctggagctt tttctttgat ttgtttcaag
    17761 actggctcaa gagtttcgta agaagtaaca cctgaaatat cgataccata tttggcaagg
    17821 agagttccgt tgaaggtaaa gttttgagat gatgctacgt tggctgcaac tggtacagcg
    17881 taaatcttac catttacagt attacccttg atataagctg gatcaagtgc cttgtaaagg
    17941 tctttacctt cttttttgta caattctgtc aagtcagcat aagcaccttt ttgagcattt
    18001 acaatatagt tatctgcaaa ggcgatatca tagttttcac cagatgatgt gataactgac
    18061 attttcttac catagtcacc ccagccaagg tattggatat ccaatttggc accaactttt
    18121 tcttcgatga ttttgttggc atttgctaac aattcatcca agttatctgg tttgtcaccg
    18181 atttggtaca ttttgataac agatttgtca cctgaatcag cagctttttt gctgttacct
    18241 gtcaagttgc cacaagcagc aagacctgca gccaaagcga ctacactagc agatgcaaaa
    18301 gcatattttt tccaattttt catgataaaa actccttttt ttatttttaa acttataaac
    18361 aatgtaatga tcttaacttc acgcaaggga agtttggaaa tgagaaatgt tctttttcaa
    18421 taagcactat tctttcacac caccgatagt caaacctttt acaaagtagc gttggaagaa
    18481 tggatacaaa atcgcgattg gaagggttgc taccacaacc atggccatac gacctgtttc
    18541 tttcggtaga gcaactccca gttgaccagt caagccgacc gctttggcaa tgtagtccat
    18601 attttgttgg atttgcatga gcaaatattg caatggatac aagttatcac tcttgatgta
    18661 aagaagggcg ttgaaccagt cattccagaa accaagagct gtcaaaagcg tgatggttgc
    18721 gatacctggt agtgacaatg gcaaacagat ttggaagaaa atccgagcct cactggcacc
    18781 atcgatacga gccgattcga gaatggcttc tggaatggtc ttcttgaaaa aagaacgcat
    18841 caagatgata ttgaatggtg agagaagcat tggaacaatc aaagcccaaa cagtgtcacc
    18901 aagctgaagt acacgggtca ccatgatata acctggtacc aaaccagcgt tgaacaacat
    18961 actgagaagg acgaagatgg taaaaaatct gcgatactta aaggttgtcc gtgaaatagc
    19021 gtaggcatag gttgttgtga taaagacatt tgtcaatgtc ccaactacgg ttacaaagac
    19081 agagatgaag agggcttgta ggattttatc cttaaactgt gccaaaaact caaaaccgtc
    19141 taagccaaat tgggatggga agaagctata gccgtattgg aggaggcttt tctcgtctgt
    19201 cactgaaata atgataacga atacaaaagg taggatacaa gagagggcaa tcaaacccga
    19261 aatgatactg aagaagatat ctgctttctt actgaaggag tgaatgccga cattatcaat
    19321 tttttctttt ttaattttct tttttgccat attctcctcc tttctagaac aaagctgagt
    19381 ttggatcgac tcgtcttgca agcaagtttg ataggataac cagaatcaaa ccaacaacgg
    19441 attggtaaag accggctgct gcagccatac cgatatctgc tgtctgagtc aaaccattaa
    19501 agacatatac gtccaaaacg ttggttacat tgtaaagctg accagcattg tgtgggattt
    19561 gatagaagag accgaagtct gcgcggaaga tatttccgac tgcaaggatg gtcaatacag
    19621 ttacaagcgg agtcaactga ggaatggtta cattgcgaat acgttgccac ttgctagctc
    19681 cgtccactgt cgctgcttcg tagtaggttg gatcaattcc catgatcgtc gcatagtaca
    19741 tgacactgct atatccaaag cctttccaaa tacctaggaa aagtaggaga tagggccaga
    19801 tgcccaggtc agcgtagaaa ttgacttctt tgagaccaag actttccaat agatgattga
    19861 acaccccttt atcaatattt aggaaggcat ctgtaaagaa actgatgata acccaagaca
    19921 agaagtaagg gaacaacata gaagtttgaa aaatcttcac cattctctta gaacggagct
    19981 cgctgaggat aatggcaatc cctacagata caactaaacc tagaaagata aagccaagat
    20041 tgtagaggac agtatttcgt gtgataataa aggcgtctct tgaactaaat aagaatctga
    20101 aattatcgag tccgacccat ttactattta tgatactatc tatgaaacca ttactggtca
    20161 tgtggtagtc tttgaaggca accacgttcc caaatactgg aatgtaaaag aatagaatca
    20221 accagagtgc ccctggcaaa accatcaaga gaaagatcca gttgtctctc aatgtttttg
    20281 aaaacttttt cataatttcc tcccttttta ttttgatatc catctaaaaa ttctttttta
    20341 gacttttgat aacgattaca ttattagtat actcctattt gcaggttagg ttaaactcct
    20401 aattatagaa aaaactccac aaattatgta gcagatttaa aactttatca ccactatcaa
    20461 acaaatgtcc taaatcaatt gtttatttta tctctattag cccagtgatg gcgtcactct
    20521 gttataagca tccaacaacg gggtatactg aaaaatctcc agactaggga actcagcgat
    20581 agttcctaat ctggagattt ttaatatgtt attaggcgtt tgctttcaac ttagcaataa
    20641 cctctttaag attatcaatc aactctgctg cagtatgctc agagcctttt tcatctgcca
    20701 agaacaaaac tgctttttga agttcttctt gagagttttc aaggacatcc ttatctactg
    20761 tttcaaggtt tgagtcttta agaagtttac ttaattcctt ggctaatttc ttgagtttga
    20821 tttgcagact catcttctcc tgctgtttct ttgcccgctg tttgtcctcc atccttagtt
    20881 gctgactggc tttccttaat ggactctagg gaagcaatgg catctttgac tgtttgcaag
    20941 atatcacgta aaccttgctc tatcaaacta tcatctgcaa aagctttctt agagtctgcc
    21001 aaaaccagac gtgctgaatc tgtggtagga ttcgatacac ctgtcaatga tctcaaaaga
    21061 ttttctaagg tttgagtctg cttactaata ctagactaaa atcaaaaagc attatataac
    21121 agtgatatga aatcaactaa agaagaaatc caaaccatca aaacactttt aaaagactct
    21181 cgtacagcta aatatcataa acgccttcaa atcgttctat ttcgtctgat gggcaaatct
    21241 tataaagaga ttatagagct tttatagtga tttgaaataa gatgtgaaca actctatcag
    21301 gaaagccaaa ttaatttata gaaatatttt agcagccaag gtgtactgtt atagattcaa
    21361 tacact
//
LOCUS       DBJKQU010000031        21304 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.031, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000031 DBJKQU010000000
VERSION     DBJKQU010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21304
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.031"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(<1..1099)
                     /gene="phtB"
                     /locus_tag="ACSUUC_001358"
     CDS             complement(<1..1099)
                     /gene="phtB"
                     /locus_tag="ACSUUC_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HHQ8054558.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVLKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPS"
     gene            complement(1257..3707)
                     /gene="phtA"
                     /locus_tag="ACSUUC_001359"
     CDS             complement(1257..3707)
                     /gene="phtA"
                     /locus_tag="ACSUUC_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HHQ8054559.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQTSQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            complement(3960..5693)
                     /gene="ptsP"
                     /locus_tag="ACSUUC_001360"
     CDS             complement(3960..5693)
                     /gene="ptsP"
                     /locus_tag="ACSUUC_001360"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HHQ8054560.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(5699..5962)
                     /locus_tag="ACSUUC_001361"
     CDS             complement(5699..5962)
                     /locus_tag="ACSUUC_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HHQ8054561.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            6313..6531
                     /gene="nrdH"
                     /locus_tag="ACSUUC_001362"
     CDS             6313..6531
                     /gene="nrdH"
                     /locus_tag="ACSUUC_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HHQ8054562.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            6612..8771
                     /gene="nrdE"
                     /locus_tag="ACSUUC_001363"
     CDS             6612..8771
                     /gene="nrdE"
                     /locus_tag="ACSUUC_001363"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HHQ8054563.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            8959..9921
                     /gene="nrdF"
                     /locus_tag="ACSUUC_001364"
     CDS             8959..9921
                     /gene="nrdF"
                     /locus_tag="ACSUUC_001364"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HHQ8054564.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            10103..10864
                     /locus_tag="ACSUUC_001365"
     CDS             10103..10864
                     /locus_tag="ACSUUC_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHQ8054565.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(11149..11400)
                     /locus_tag="ACSUUC_001366"
     CDS             complement(11149..11400)
                     /locus_tag="ACSUUC_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HHQ8054566.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQMPCLTSEELKSLGKWYVSTGK
                     EWICHSDADLEEFKNLFLNFINPEEWDTISFDSDFMPFQ"
     gene            complement(11443..12849)
                     /gene="lacG"
                     /locus_tag="ACSUUC_001367"
     CDS             complement(11443..12849)
                     /gene="lacG"
                     /locus_tag="ACSUUC_001367"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HHQ8054567.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            complement(13064..14758)
                     /locus_tag="ACSUUC_001368"
     CDS             complement(13064..14758)
                     /locus_tag="ACSUUC_001368"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HHQ8054568.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            complement(14760..15077)
                     /locus_tag="ACSUUC_001369"
     CDS             complement(14760..15077)
                     /locus_tag="ACSUUC_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHQ8054569.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            complement(15113..15949)
                     /locus_tag="ACSUUC_001370"
     CDS             complement(15113..15949)
                     /locus_tag="ACSUUC_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHQ8054570.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            complement(16183..17163)
                     /gene="lacD"
                     /locus_tag="ACSUUC_001371"
     CDS             complement(16183..17163)
                     /gene="lacD"
                     /locus_tag="ACSUUC_001371"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HHQ8054571.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            complement(17165..18094)
                     /locus_tag="ACSUUC_001372"
     CDS             complement(17165..18094)
                     /locus_tag="ACSUUC_001372"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HHQ8054572.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQDPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            complement(18105..18620)
                     /gene="lacB"
                     /locus_tag="ACSUUC_001373"
     CDS             complement(18105..18620)
                     /gene="lacB"
                     /locus_tag="ACSUUC_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HHQ8054573.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHHESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            complement(18651..19076)
                     /gene="lacA"
                     /locus_tag="ACSUUC_001374"
     CDS             complement(18651..19076)
                     /gene="lacA"
                     /locus_tag="ACSUUC_001374"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HHQ8054574.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            complement(19233..19730)
                     /locus_tag="ACSUUC_001375"
                     /pseudo
     CDS             complement(19233..19730)
                     /locus_tag="ACSUUC_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            complement(19746..20549)
                     /locus_tag="ACSUUC_001376"
                     /pseudo
     CDS             complement(19746..20549)
                     /locus_tag="ACSUUC_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(20557..20859)
                     /locus_tag="ACSUUC_001377"
     CDS             complement(20557..20859)
                     /locus_tag="ACSUUC_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHQ8054575.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIILPAKQNMV"
     gene            complement(20897..>21304)
                     /locus_tag="ACSUUC_001378"
     CDS             complement(20897..>21304)
                     /locus_tag="ACSUUC_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHQ8054576.1"
                     /translation="FDQVASLLEEREIVTPTYREALITREKSFPTGLDMEFLGKDLPN
                     VAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGKEVEVSLLFFIINNSSSSQTNILA
                     QLMDFFTGNGYLEDLSKISEPEKLYAYIAEATA"
BASE COUNT         6291 a         4381 c         3820 g         6812 t
ORIGIN      
        1 gacttggact aggttccgga gtcgattgtg gacttggttg ttctggtctt gaatctggta
       61 cccaatggtt tgaacgataa cgaaggggaa taatacgagc aattcgtttt tccaattcag
      121 acatttgttc ataagggata aagtggtaat ggttaccatg agggacagct acacctctgg
      181 cggttcgact tgtgatttgc gctgggtcga aaataaggcc atcagattcc acatggcgtt
      241 ctgataaggg tttagcatac aattcacgta aaaggcttga aatgttttcc ccttgatttt
      301 gatgataagt tggagtgaca gtcagattgt ggttctctga caatcttggt tgagctggat
      361 ttgcattata actagaactt gaagaaggac gagatccctg cttcccattc caataggctt
      421 ctgcagcagc taactcgcta gctgataact cattcttagg aatgtaatgg taatggtcgc
      481 cgtgaggaac gatataagca tcacccgtgt cctcaatgat atcagatgca ttgaagatat
      541 acccatcatc cgttgtataa cgtccttggg ctctggctgc agcaacagca ttatctgctc
      601 ttgagttatg attatgactg cgttcctgct tctgacgttt aatctcttct tttgtccgaa
      661 tattatccgc atgagctgca tccttaaggt aaacatagta tttaccgttt accttaagga
      721 cataaccacc cttgatttca ttgacaatgt ctgaatcctt caactgataa ttcggatctt
      781 tcatgaggag ctcttcactg atgatggcat cataaggaac cttgccatta tagtaatgat
      841 aatggtctcc atgagaggtc acataacctt gatccgtaat cttgataaca atttgttcgg
      901 cgttgatccc ctccctctta ctgacttcat ctggtgtcaa gttttctgcc ttttgaccag
      961 cctgatcacc atctatataa gcaactcgat tagactcttt cttatcctga ccagcttggt
     1021 aacgtccaag ctcataggaa caaacactta gggcaaggac tgccactgaa cctgctagat
     1081 attttttatt gattttcatt ctttcctctt ttcttaagta tatttgattc actataaagt
     1141 aataaaccgg ttaattaact agttaatagt ttactctttt taatattgct tgtcaagaat
     1201 tttacatata tacataataa aaatgaaagc ctctttatcg agactttcat ttttcattag
     1261 tttatttttt ccttacttac agatgaagga ttacttcctt ttaacaacgc aagtaatttt
     1321 tctgcttctg ccatgatact attgttatcc ataatttgaa gagtcaaatt atttcgtaaa
     1381 ccagctagag tttctgttgc attggctttc agactagaat ccgttacttt cgcaagcaaa
     1441 acttctgctt ctttgagttg ggcttctact ttttcagtct ctacttgagg gacttctggc
     1501 tcagcaggtg tttcctctac tggctcttca tccgctttga agttcttatt tggatcttca
     1561 ctgtggtctt tcttgcctaa cacatgctca ctggcattgc cccatccatc attagaatgt
     1621 ggacgttcgt cagggtgttc tacgtagtac ttaatcgtcg caaacaaatc ttccaaggta
     1681 tagccatttg gagctttgta tgtgtgatca tcaaaccaag caaatttaat gttatggtaa
     1741 tgatccttat gaggaataat caaattaccg tttttaacct caactgtatg ctcaaccata
     1801 tatggaagtc gaacgagtgg aattcgtttt tcccctttca cacgattgta aatagctgct
     1861 gcactatctc cagttggatt tgctttaaca tctgcgtctg gagatggagg taggatacct
     1921 ttttctttag tataggcttg agctgcaact ttttccttat cagaaaggct gtcttttcca
     1981 atccagtgac tatggcccat atgaggcgtt acatatgcat ctccttcatc actgattata
     2041 tcatgttcat caaaaatata accatctgac gttgtatact tatcagctaa ttgagcaata
     2101 cgaacttcgt cttcagtata ctcaatttga gaatttggct tgccaagtcg ctctggatgg
     2161 gtaattggtg ctaggaatgc caataaatca tctaccaatt tttctttatt agtcgattca
     2221 tcattcaagc gttctaataa tttgtctaag gcttggaaat cagaattacg acccttattt
     2281 tcaaacaagg ctttatgagc ctcagttaac agattatatg ctttatcata aaattcttgg
     2341 tcacgaggag caacattttc ttttttagca gttaaagtgt gtgaaacact ctcttgtttt
     2401 gataacttgc tttcaagatt tttaacagtt tcagatggta aatctttcgc aaagacataa
     2461 cgagagatgc ccttttcttc gaatacatat ccttccccaa cttttcgtac cagctgacta
     2521 accaaagaag aatttgagtc tattttaaga tttggtgcag gttgcgggcc tggactaggt
     2581 tccggagtcg gttgtggact tggttgttct ggccttgaat ctggtaccca atggtttgaa
     2641 cgataacgaa ggggaataat acgagcgatt cgttcttcca attcagacat ttgagagtaa
     2701 gggatgaagt ggtaatgatc tccgtgtggc actgcaacac ctctagctgt tcgacttgtg
     2761 atttgcgctg ggtcgaaaac aaggccatca gattctacat gtcgttgact caaaggcagt
     2821 ttgtagagct gtttcaagag actatcaatg tcattacttt gacttgtttg actgttagtg
     2881 ttgctgttgt tgcttgtgtt agtatttgta gttcctggat tgcttacaga aggtacccag
     2941 tttgttcttg aagtgttatc gctattttgt cggcgatagg ttcttgaatt tgacagattt
     3001 ccccgaccag ataggaaggc ttctgcagca gccaactcgc tagctgataa ctcattctta
     3061 ggaatgtaat ggtaatgatc tccatgagga acgatataag catcaccagt atcctctatg
     3121 atatcagaag cattaaagat ataaccatca tctgtagtat agcgtccttg cgaacgtgcc
     3181 aaggcaacag caccatcgtt tcttggagtc ccaccttcac gatgttgact atgttcttgt
     3241 ttttgtcgat tgatttcctc ttttgtacgg acgttatccg cgtgggcagc atccttaagg
     3301 taaacatagt attttccatc taccttgata acatatccac ccttgacctc attaacaata
     3361 tcctcatctt ttagcttata gttcggatct ttcatgagta attcttcact gaaaatcgca
     3421 tcataaggaa ccttaccatt gtaataatga tagtggtcgc catgtgaagt gacatagcct
     3481 tggtctgtta tcttgatgac gatttgctca gcattgattc cttcacgctt gctaacctca
     3541 tcaggagtca aattctccgt tttttgcgtc gcttgttttc catctatata ggaaacacga
     3601 ttattttcct taaccgttct agcttgatac agtcccaact cgtaagaaca aacacttaaa
     3661 atcaaagctg ccgcagaacc aacaaggtat ttcttattaa ttttcatcga aactctcttt
     3721 ctatttgata tttctagttg caattcattt ctaaattgca gaaactcctc tctattactt
     3781 aactggttaa tagtttactc ctaaatctcc aacttgtcaa gaattttatg aaccatttaa
     3841 gtattttttg ttctgactac tactttttca agaaaatctt tctataagaa agattttctt
     3901 gaaaattctt tttaaaatat caaaaaaatc cctgtaactg agttgcaggg acttttcgat
     3961 taatcaaaat taacgtattc tttttgaagt tcaagaactt cttccattgt tgagcattct
     4021 gtaagggcac ggtttgcgta ctcttccatc ttagctgtgt cgagtttctt catcaagctg
     4081 cgtgtacgaa gtacagatgt tgctgacata gagaactcat ccaagcccat tccgacaaga
     4141 agtggaacag cttgttggtc accagccatc tcaccacaca taccagccca tttaccttca
     4201 gcgtgagctg ctttgatcac attgttaatc aagcgtagga ttgatgggtt gtatggttgg
     4261 taaaggtatg aaacttgttc gttcatacgg tctgctgcca ttgtatattg gatcaagtcg
     4321 tttgtaccaa ttgagaagaa gtcaacttct ttagcaaatt ggtctgcaag catagccgct
     4381 gcaggaatct cgatcatgat accaacttgg atgttatccg caactgcaac accttcagca
     4441 agaaggtttg ctttttcttc atcaaagact gctttcgctg cacggaattc tttcaagagc
     4501 gcaaccattg ggaacatgat acgcaattga ccgtgaacag acgcacgaag aagagcacgg
     4561 atttgtgtgc ggaacatagc atctccagtc tcagagatag agatacgaag agcacggaat
     4621 ccaaggaatg ggttcatttc gtgaggcata tcgaagtaag gaagttcctt atctccaccg
     4681 atatccattg tacgaacgac aacaggttta ccgttcattc cttcaagaac agccttgtat
     4741 gcttcatact gctcatcttc agttgggaag tcttgagaat ccatgtacaa gaactctgta
     4801 cggtaaagtc caacagcttc tgcaccgttg ttgttaacac cttcaacgtc ttttggagta
     4861 ccgatattag cagccaactc gaagtgttta ccgtcagcag tcactgtttg agcatctttc
     4921 aagagcgccc attcagcttt ttgtttcgca taagcttcac cagctgcttt aaattctgcc
     4981 gcttgttcat cagttgggtt gataataacc tcaccagtga tcccgttaac agcaaggatg
     5041 tcaccgtctt taacgatttc agtgatgttg tttgtaccta atacagctgc aatttcaagt
     5101 gtacgtgcca tgatagctga gtggcttgta cgtccaccga tgttggttac aaaagctttt
     5161 acaaagtttt tgtccaattg agctgtatca gatggtgtca agtcatgtgc aatcacaatc
     5221 acttcttcat tgatagaagc tgggtttggc aattttttac caagaaggtt tgccaataca
     5281 cgttttgtca catcgcggat atccgctgcg cgttcttgca tgtatgggtt gtcttccatg
     5341 ccttcaaaga tagtgataaa catatctgta acttctttca gacctgcttc tgcattcact
     5401 ttcttcgcac ggatagtttc cttgatttgg ctgatcattt ctgggtcagc aagaaccatt
     5461 aagtgagcat caaaaacttg agctgcttct tcaccgagcg tacctactgc tttctcgcga
     5521 ataacagaaa gctcgtcttg tgatgcctgt agagcggcat caaggcgagc ttcttctgcg
     5581 tttgtatctt cgactgtaat agtctcaaat gacaaatccg gctgaacgag tagatatgct
     5641 tttgcaactg caacaccgtc agatgctgcg attcctttaa gcatttctgt catttccctt
     5701 atgccaatcc ttctttttcc attgtttctg agattgcagc gatagcgtca tctgcatctg
     5761 caccttcagc tgagatagtt acgtcagcac cttggccaac accaagactc ataacaccca
     5821 taattgattt aaggttaact gatttacctt tgtactcaag agtgatatct gaagcaaatt
     5881 tgctagcagt ttgtaccaac aatgttgctg gacgtgcgtg aatacctgtt tctgccacta
     5941 cgtggaaatc tttagaagcc atagtttgac tctccttttg ttctttcttt ttttgagtta
     6001 tatgtgataa cccttacaat ttagtattat accatcttct aggatttttt tcaagcattt
     6061 tctggatttt ccttcaattt cctttcagat aacttgctga aaatcttcta tcctagataa
     6121 caaaacacag gatatagttt ctttaaaaac aatttatagg ataatcattg ctatttcaca
     6181 atacaaacac tatatattgt gtttatatat aaaaacaaca aaagaacacc actatattta
     6241 gttcaaatca ttgacaaaat tttattttct gatatactaa gatagtatta aattttgaag
     6301 aggagttaca caatggtaac cgtttattct aaaaacaatt gtgtccaatg taaaatgacc
     6361 aagcgtttct tggacagtaa taatgtctct tatcgtgaaa tcaatcttga tgagcaacct
     6421 gagtacgtcg atcaagttaa agagctcggt tttagcgcag ctcctgttat ccaaacacca
     6481 actgaagtct tttcaggttt ccaaccagga aaactgaaac aattagcata atcttagtac
     6541 atcatccaga agaaactgct tttagggcta acttagaagc ctttcttttg taattagata
     6601 agggaaattt tatgggatta aaacatcttg aagacgtgac ttacttccgt cttaataacg
     6661 aaattaaccg tcctgttaat ggacaaatca tgcttcataa agataaggaa gccttggatg
     6721 ctttctttaa agaaaatgta gttccaaaca ctatggtttt tgattcaatc aaagacaaaa
     6781 tcaattacct cattgaacac aactacatcg aaacagcctt tatcaagaaa taccgtccag
     6841 agttcttgga agaattggct caatttatca aagaccaaaa cttccaattc aagtcattca
     6901 tggcagctta taaattttac aatcaatatg ccttaaagac taatgacggt gaatactatc
     6961 ttgaaaatat ggaagaccgt gtcttcttca acgcccttta tttcgctgat gggaatgaag
     7021 ctgttgcaat cgatattgcc aatgaaatca tccaccaacg ctaccaacct gctactcctt
     7081 ccttcttgaa tgctggacgt gctcgtcgtg gggagttggt atcttgtttc ctaatccaag
     7141 tgacggatga tatgaactct atcggacgtt ctatcaactc agctcttcaa ctttcacgta
     7201 ttggtggtgg tgtgggaatt accctcagca accttcgtga agctggtgca cctatcaaag
     7261 gctatgaagg agctgcttca ggtgtcgttc ctgttatgaa gctttttgaa gacagcttct
     7321 cttactccaa ccaattgggg caacgtcaag gtgctggtgt tgtctacctc aacgtctttc
     7381 acccagatat catcgctttc ctttcaacta agaaagaaaa cgctgatgaa aaagtacgtg
     7441 tcaagactct atcacttggt gttgtagtac ctgataaatt ctacgaattg gctcgtaaaa
     7501 atgaagaaat gtacctcttc agcccttact ctgtagaaaa agaatacggt gtgccattca
     7561 attacatcga cattactgaa aaatacgatg aattggtcgc aaatccaaat attcgcaaga
     7621 caaaaatcaa ggcgcgggat ttggaaactg aaatctctaa attgcaacaa gagtctggct
     7681 atccttatgt agtcaacatc gatacggcta accgtgcaaa tcctgttgat ggaaagatta
     7741 tcatgagtaa cttgtgttct gagattcttc aagttcaaga accaagcttg atcaacgatg
     7801 ctcaagaatt ccttcaaatg ggaacagatg tttcatgtaa tctgggttca accaacgtgg
     7861 ttaacatgat gacttcacct gattttggtc gttctatccg tgctatggtt cgtgccctta
     7921 ctttcgttac agatagttca catatcgtag ctgtaccaac gattgaccat ggaaatagcc
     7981 aagcccacac ctttggtctc ggtgccatgg gactgcacag ctaccttgcc caacaactca
     8041 ttgaatatgg ttcacctgag tctgttgaat ttacaagcat ctactttatg cttatgaact
     8101 actggacctt ggtagagtca aacaatattg cgcgtgaacg tggtattacc ttccacaact
     8161 ttgaaaaatc agactatgct aacggaagtt actttgacaa gtatgtaact ggtgaatttg
     8221 ttccaacatc agaccgtgtt aaagaactct tcaaaaatgt ttttatccct ggtgttgctg
     8281 attgggctga acttcgcgac aaggttcaag aagatggtct ttaccaccaa aatcgccttg
     8341 ctgtagcgcc aaatggttct atcagctata tcaacgacgt ttctgcttct atccacccga
     8401 ttacgcaacg tatcgaagaa cgccaagaga agaaaattgg taaaatctac taccctgctg
     8461 ctggcttgtc tacagaaacc attccttact acacttctgc ctacgatatg gatatgcgta
     8521 aagtcatcga tgtttacgct gctgcgactg aacacgtgga tcaaggactt tcactcaccc
     8581 tcttcatgcg cagtgacatt ccaaaaggcc tttacgaatg gaagagggaa aataaacaaa
     8641 cgacacgtga tttgtccatc cttcgtaact atgcctttaa caagggaatc aagtctatct
     8701 actacgtccg tacctttaca gatgacggtg gagaagtcgg cgccaaccaa tgtgaaagct
     8761 gtgtgattta gtttctagca tagaaacatt atttttccct aagcagcact gataaaatca
     8821 aatctactat gtcataacat aatttatgta acattttaaa agtcgggctt ccgacttttt
     8881 gtgcgatact cctatagaat tatggtaaag tagaaataat tgtgagttcg caatactaaa
     8941 cacagaaaga gattttaaat ggaaacttac tacaaagcca ttaactggaa tgccatcgaa
     9001 gatgtcatcg acaaatcaac ttgggaaaaa ctgacggagc aattttggct cgatacacgt
     9061 attcccttat caaacgactt ggatgactgg agaaagctat ctaacaaaga gaaagacttg
     9121 gtcggaaaag tttttggtgg tttaaccctt cttgacacta tgcaatctga aactggggtt
     9181 caagcccttc gcgcagacat ccgtacacca catgaggaag ctgttttcaa taacatccaa
     9241 tttatggaat ctgtccacgc taaatcttac tcatcaatct tttctacctt gaatactaag
     9301 gctgagattg aagaaatttt cgaatggacc aataccaatc cttacctaca aaagaaggct
     9361 gagattgtca acgaaatcta cctaaacggc agcccacttg aaaagaaagt tgccagcgtc
     9421 ttcctcgaaa ccttcctctt ctactctggt ttcttcactc ccctctacta tctcggtaac
     9481 aacaaactag ccaacgttgc agaaatcatt aaattgatta ttcgtgacga gtctgttcac
     9541 ggaacctaca ttggttacaa attccaactt ggtttcaatg aattgcctga agaagagcaa
     9601 gaaaaactca aagaatggat gtacgaccta ctctatactc tttatgaaaa tgaagaaggc
     9661 tacacagaga gtctttatga cggtgttggt tggactgaag aggttaaaac cttccttcgc
     9721 tacaatgcca ataaagctct catgaacatg ggacaagatc cacttttccc agattcagct
     9781 gaagatgtca acccaatcgt tatgaacggt atttcaacag gaacttccaa ccatgacttc
     9841 ttctctcaag tcggaaatgg ttaccttctt ggcgaagttg aagccatgca agacgatgac
     9901 tataactacg gtttagacta attctccatc actctcaatc atcaaaaagt aaactagaaa
     9961 catcaaagtt ataacccaac aaaaatatcg aaagttttga aaacaaactt cgatattttt
    10021 gtttttgttt cattttgttg tttttgtatt tgaatgatga gtttgtttat ggtaagatag
    10081 tagtaggaaa cgaggtgata atatgctcaa acaagaaaaa ttaaccaaaa ttttagagat
    10141 agtaaatagt aaaggaacca taacagttaa acagattatg gacgaaatag ccgtttcaga
    10201 tatgactgca aggcgctatt tacaggaatt agctgataaa gatttgctga ttcgtgtgca
    10261 tggtggagct gaaaaacttc gaaccaactc ccttttgact aatgagcgat caaatattga
    10321 aaaacaagcc ctccaaacgg cagaaaaaca agaaatagcc cattttgcag gcagtctagt
    10381 agaagaaaga gaaactattt tcattggacc aggaacaaca ttagagtttt ttgcgcgtga
    10441 gttgcctatt gacaatatcc gcgtcgtaac caacagtcta cctgtttttc tgattttaag
    10501 cgaacgaaaa ttaacagatt tgattttaat aggtggaaat tatcgcgata ttacaggtgc
    10561 ttttgttggt acattgaccc tacaaaatct ctctaatctc caattttcta aagctttcgt
    10621 tagctgtaat ggtattcaaa acggagctct agctactttt agcgaggaag agggagaggc
    10681 tcaacgcatc gctttaaata attctaataa aaaatattta ctcgcagatc atagtaagtt
    10741 caataagttt gatttttata ctttttataa tatatcaaat cttgatacta ttgtttcaga
    10801 ttctaaacta agtgattcaa tcctttttaa gctatctaaa cacattaaag tcatcaagcc
    10861 ttaataaact gaaagagcct gggtaacaac tcaatttcag aagaaaaaaa gtaaatcttc
    10921 ccacaataaa aagcatagta tcaggtgttg aaacacctga tactatgctt ttttctatat
    10981 caaagacttt ttgcccaatt cctcaaagct atacattgag aaatctgcga ctcgcttcct
    11041 agtttaaagt tgctctttga ttttcattga gtataagcaa cgtgattaga taagagtttt
    11101 acagagtact aaatataaga tttaactttt ttgagaaatt ggttacgatt attgaaacgg
    11161 cataaaatct gaatcaaagg agatagtatc ccattcttca ggattgataa aatttaaaaa
    11221 tagattttta aattcttcca gatcagcatc tgaatgacaa atccattctt taccagtcga
    11281 gacataccat tttccaagac ttttcaattc ttcactcgtc aaacacggca tttgagagca
    11341 tttttcgaaa tttataatat aaactttttc ataaatagat tggataaaat ctttgaacat
    11401 ctttttgact tactaaaatt ctatatctaa tgactaattc tactagtcta taatctgagt
    11461 ttccgctact ttcttgtacc agtgagctga tttcttagga taacgttctt gagtttcaaa
    11521 atctacgtag aagagaccat aacgtttctc ataaccgttt gaccatgaga agacatccat
    11581 taatgaccaa atgaagtaac cttttacatt agctccatct gcaatcgcat cagacaagat
    11641 ctccaagtgt tgtttcacgt aatcaatacg accatcatcg taaacagtgt tatcaacgaa
    11701 ctcatcttta tagccgagac cattttcagt gatgtaaatc ttcttgtagt taggataatc
    11761 tttcttcaca cgcatgattt ggtcatacaa accttgaggg tagataatcc aatcccaatc
    11821 cgtacgtggt acatagtcag gagctacacg acgaccaaca cctttgattt gatacttaga
    11881 gcttcctttt tcacctttac cattatggat aatttcagtt tctccatcaa aggcttccat
    11941 ccagtcactc atatagtagt tgattcctag gaaatcattc aagtcttttg cagcttctaa
    12001 tgctgtaaaa tcttcttcac gaagatccaa actaccacca ttgactgata agatatggtt
    12061 gacaccttcc atggtttcag ctgaatagcg acctagataa gttgcgtcta agatgaattt
    12121 attgtggatg atatcttcca actcagctgc acgaacatct gctggatttt caggatctag
    12181 aggatattta gtaggcaggg cgtgaacaac accaatttcc cctttatagc ctttctcttt
    12241 gtacaatttt accgcgcgtg catgagacac catcatattg tggtgtgatt gaaagacttt
    12301 ggcaaggtcg tactggatac ctggagggaa tttcccaacc aaatattgac catcaccgat
    12361 tggtccaatt tcattaaagg ttgtccaata gtttacttct ggaaattctt caaaacagaa
    12421 ggcagcgtag tctacaaaat gttcgatatt ttcacggttt aagaagtctc catttgagtg
    12481 gagagcttct ggcgtgtcaa agtgatgaag agttacaaaa ggctcaacat gacgtttatg
    12541 acactctgca aataaattat gataaaactc aacaccttta gcatttactt ggccgtaacc
    12601 agtcgggaaa atacgtgacc aagcaataga aattcgaata ccattgacac catactcttc
    12661 tgctagcttg aggtcaactg gatatcgatt gtaaaaatca ctagctggtt cggcagtgta
    12721 ccagtagtta tcctcaagat atttatccca agcaactggt ccttttccat cagtatgtgt
    12781 agcaccttct gcttgataag cagctgttgc gccaccgaaa ataaagtctt ttggaagtgt
    12841 ttttgtcatt tttttcacct atttcttgat ttaaataaag taaaagtgag aggagaggag
    12901 tcagtgagcc atgcttctcc atctcacttc ttgtaccaag tcactgaatt gtgacatgag
    12961 gaggtaaaaa cgatatcttt ttaccgacga attaataagg cgattaggaa attcgccata
    13021 gcgatttccg taacgatggg agactgtttc acagttccta gccttaatcg aattgctctt
    13081 gtacgaatgc tagggcacct tttccatcac gagttaattt gatgtattga gcgccttctg
    13141 tcttagcaag tttaataccg agcttatctg tttctgcctt catatcttca aagtttgaag
    13201 caacttgagg agcaaggata accaaatcaa actctggcaa catttcacgg tgagcaccat
    13261 agccgcctgc tgctgctttc acagggacat tgtattctgc tgctgcctta ttcaaagcat
    13321 ttgcaaggag accacttgta cctccacctg cacagagaac gaggacattt gtttcttcag
    13381 tgatggtatt ttgtgctgca tcgacacccg ctttttcaag aatagcatcc gcttttgcag
    13441 tgttgaagtt tgcagcaact ttttctttca attcagatga agagtttcct ttccgttctt
    13501 cttctaaaat ttgatggtca taaactttaa caaatggata atagattaaa gtgtcgataa
    13561 tgattaaagt tatagccaag acgaatgaca atggagccag cgccgttccc ataacaatac
    13621 caattggagc aggtgttgtc caaggtaaaa taatactgaa actattcatt tgtagaacat
    13681 ctacaaaaaa tttcataatc caaacattga taataggagc agtaacaaac ggaataaaga
    13741 agataggatt taaaacaatt ggagcaccaa ataggattgg ttcatttacg ccaaagaaag
    13801 taggaactac agacgcacgt ccgacaattc tatttctttt tgatttacat aaccacataa
    13861 acataaatgg aactactagt gttgcaccag taccacccat tgttacaaca aaagtttgag
    13921 taactggatt taaaatttta tctgcgtgca taccagcttg cacaagctga acattagctt
    13981 ctatatttgc ataactgata gctacaatta aaggttctac aacagatggc ccatgaattc
    14041 caacaaacca aaagaaagca taagcaccaa atacaatagc taaaccgata taaccatcag
    14101 tagctgaaaa tagaggggct aatattttac caacagattc tgctacattt gtaccaaaaa
    14161 tatttctaac aattaaatcc aatccatata ttgaaagaac agataaggca aacggaataa
    14221 catctttaaa aacttgtgca atatttggtg gaacctcttc aggaagtcta atggttacat
    14281 tatttttaat acatacttta tagatattta ctgtaataaa agctgccaaa aatgcagtaa
    14341 gtaatcctct agtacctaaa agaccattag caaatccacc ttcaattgga tcagctgcca
    14401 gtattaacaa tccaacaaca gctgctaaaa aagttgacat gtagttgatt tggttggttt
    14461 tctccatact acgtgtatta actgaatctg ttaacgattt tgcagttgtc ccagctacta
    14521 agagagctaa aatccccatt gagtagttgt aaggtttcaa aataaaagct aactgttcat
    14581 cagaccattt aaacccaaaa atattgggca cagcagctat tagtataaaa atacttgaga
    14641 ataatactgc tggcatactg gaaataaaac catcttttat cgctcttaag tatatatttc
    14701 tcgataattt ctcaaagaaa ggctttcctt tctcaataaa aattattaac ttatccattt
    14761 tatttaactc ctctcttgta aagttcaatt aaatggtgca ttaggtcttt taacaagata
    14821 gttgtcatca agtgatcttg accatgcatc atggtcacac tatacgctaa gtcctcacca
    14881 gaagcttcct tagtcaatag acttgtttgc gcgtggtgag cctctgcaat acagctacca
    14941 gcttcctcta ccagagcgtc cgctttttca aaatcaccag cttcagcagc cttcaaggct
    15001 tccaatagtt ttgaacgagc atcgccagca taggctacga tttcaaaacc taacaatgtt
    15061 acttcttctc tattcatgat agaattctcc ttatatagtt ttaaataaat ttttatgaca
    15121 ataaacgttg gatatgtaga actagataaa ctcgttcact tttatacaaa tcaagacccg
    15181 tatgttgcgt aatcacatca tagatcttgg aaccaatctc gaaggctttt ggataggatt
    15241 gtttaatatg atcttccata tccagaagtg attggttatc atctctagat ctgtctaaat
    15301 aatccaagaa ataattcaaa tggatcataa agcgatcata gaaatggtta ttctttttag
    15361 ttcgttgaat tgcatagtcc gttaaaactt cttcaacatt cctgagaatt tctttcctct
    15421 tatcaatcga ctccacaagt tccacttcat tttcaccttc agcattaatg aaatgataag
    15481 caatccgaat aatttcgtcc tcaggaaaat gatctgctag cttctgacgg taaatttcaa
    15541 aagcttcatt tgcgatttga aaagcgacag gatacttagc ggaaatatct ggcagattac
    15601 tatccttgta ccttccttga gttagagctt gataagaaca gtaaatatga tctgtcaagg
    15661 ttacatagag atactcttga atcggataat gatatttctt tgatagctta tcaatgattt
    15721 cataggtcac tgtgataaaa tcaagcggaa catctttgag aagagccata aagttttctc
    15781 tggactcttc ggtcttcatc cgaaagattt tctcaacctg attttcagca atcaaatccc
    15841 ccttcttctt tccgaatgca attcccttac caattacaat cacctcttct cccttatcat
    15901 ttctgacaag cgagacattg tgattcattg gatttagaat tcgatacatg tcaacctcct
    15961 tttatatctt aaaggtatat aagtacaaaa aatgaccaca aatgaactag aaaatcagct
    16021 gatttctaat tcacctgtga tcatgcctaa tattacttag taacactcac cttgtattaa
    16081 cttgtgattt aagtatagca caagtaagtt attttgtaaa cctttacata caactttttt
    16141 taaatttttt tagattcatg ttcctaaact aggaggactt tcttacacac gttctttcca
    16201 tgaagtcgct gttgtttgaa gaactttatt gagctcatca atgttttcaa atccagttgt
    16261 gcgaagccat tcgcgagctg ctgcttcacc atctttgatg taagcttcaa ctgatcctgc
    16321 ccatgtagca cggccacaaa gaactccgtt aaagtttgca cctgattcat gagcaaatac
    16381 aagagtatct tggaagagtt tagctgatac accagcactc aagtagatgt atggcaagtt
    16441 cgttgcttca tcttgcgctt tgaagaaggc tgctgcttct tcacgtgtat aaactacttc
    16501 accttcagcg aagccttcaa catatttaat gttaacagga acttcaactt tcaagacatc
    16561 aatgttaaag cgtgggtctg aaaagacttt catagcgccg ataactttgt gtggttttac
    16621 tttcgcgtat tctacagaac ctgcatccgc aattttttca tcgtaagcaa ggatttcaag
    16681 gaagaatggg atatcttcag ccacacactc agaaccgatg cgttcgatgt aggcttgttt
    16741 ttcttgattg agttcgtctg agctatctac atcatagtaa agcaagaatt taactgcatc
    16801 tgcaccttct tctttaatac gttttgcaga ccagacatcc aagcagtctg gcaagcgttt
    16861 tgtgcttgtt gtgtcataac ctgttttttc ataagcaagg agaagaccag ctttttcatc
    16921 aagagcttta gttgctggaa gtccatactc agggtcaaga agcatagatg aagcgtattt
    16981 agtcaattca tctgctacca agactttaag ttcttccatt tgggccacag ttggttcttc
    17041 tgtttggtgt tgagccatga ggcgtttcaa agcaccacgt tggtcaaatg caagagctga
    17101 gatgatacca ttttcatcag aaagtttttc taagcgtaca cgtttttgtt ctgttaaagc
    17161 cattttatac ctcttttact attaattgat catatagaac ttgatagttg gccatgttga
    17221 catgaccagt cattttttct tgagcattga gcataccaag gacatttgcc ttgatgagta
    17281 attctgcatc cgattctttg tgaagaagtc ctgaagaaat tcctgccaca gtagagtctc
    17341 cagatccaac aggatttacc acctgaattc taggaatatc taccttgtag aaagtgtcac
    17401 catgtttggc aaaagtaccg ttggcaccaa gtgaaacgat aatccattca atccctgcaa
    17461 acaaagggtc ttgaagtact tcttttaatt catccaaatc ctcagaaact tctcttccaa
    17521 gaagctgaga caattcttca ttatttggtt tgatgactgt tggtttatgg ggtgattcaa
    17581 gaacagcctg aagtgctgca cctgagcagt ccaagactac aggcttgcca gcttgattag
    17641 caagttctac caagctcgca tagtaatcaa ctggaaggcc agctggcaga ctacctgaga
    17701 tggccactac ttcaactgat tccaagagtt ttttgaaatg ttccaaaaac tcttgacctt
    17761 cctgttccaa tacttcagga cctttttcaa gaacttctgt ttggttgtct ccgtggagaa
    17821 tagcgataca gttacgagtt tctccctgaa ttgagaagaa atctttcttt acttgattat
    17881 cgatatgttc aaccaaaaac tcaccaagtt tgccacccac taaaccagta gcaagaacag
    17941 aatcaccaaa ttctgaaagt actcgggtaa cattgagtcc cttaccacca gccgttttgg
    18001 ttacatccac cacacgattg acagtatcaa tcttcaactc atccaaggga taggaaatat
    18061 caatggatgg gttcattgta actgttaaaa tcataggtta cctcttagtc gtggtattct
    18121 ccgcgatccc atttttcaag gaattcagtg aagaagtttg cgtctgtttg ttgagcattg
    18181 tgactttcat ggtgttcaat tttcgcaatc aattttttgt tttcttcaga tggtttgtat
    18241 tcagcatgaa tgaaagcttc gatgatatca cacataagca attcaccagt aatcttacca
    18301 ccaaaaccga taacgttggc gttcaattgt tctttagcat aaagggctgt tgtcatatca
    18361 cgaaccaagg cagaacgaac acctggaact ttatttacag cgttgttgat accaacacca
    18421 gtaccacaga tacatacccc gagatcagct tgaccactag ttactgcttc ccctactttt
    18481 ttaccaaaga ttgggtagtg agtccgtgta tggtcatagg taccaaagtc aatgacttca
    18541 tatccttttg atttcaaaaa ttctgaaacc gccatttttt catcagttac gatgtggtca
    18601 catccaattg caattctcat ttttaactta cctttcttac tgtaatctaa ttagcccatt
    18661 ttgttcaaca tgtcaacccg gatttgatga cgtccaccgt cgtatttacc attaacaaat
    18721 cctttagcga tgtttttagc caattcatca ccaacaagtt gtgcccccat agtgatcata
    18781 cgtgagttgt tgtggccacg agtcatataa gctgaacgtt cgtcagatac ttctgcagca
    18841 accattcctt tgatcttagt tgcaaccata aatggaccag ctccataagc atcaatcacg
    18901 ataccaaggt tttgttcttc tttgtttact tctgcagcaa cagcgagagt cacatcaaca
    18961 aagtcttgac cttcagctgt aacatccaca aggtggaagt tttctttttc taagaagtct
    19021 ttcacaactt ctttcaatct caaacctgca gcatctgcac cgataacaat agacatattg
    19081 tatactcctt tttatttttt ctatgctgga ttccagcagt gtattggctg tctttaaaaa
    19141 acagtcaatt agtcctcaca aacataatat actactattg tttgaagaag tcaatagttt
    19201 gtgtttgttt ttgttattta ttttttactt ttttataaaa cttctatctc aaaccctaat
    19261 tcttcaacct gattggcttc taagagacaa acattcttct tatcttctaa atgatctcct
    19321 tcttcaagga atgttgacaa gccagaccat ggttcaaagg taatgaaagg tcccttgttc
    19381 aaagttgacc agatgatgag gtttggaaat tctgcaaaat gcactttcaa tcccttatca
    19441 tgtttaagag aacgaagggc aattgttcga gattgcaatt catccaaagt cactgcatct
    19501 gtgctgaaaa gatcataact aagatctatt tctttttgtc cctctagcca tggacttcta
    19561 tcttggaaat ccaacatacc tgtttctggg aaaggacgtg gaacagagca agtctcttct
    19621 ttctcagact ctagataata atcttcatag actccatcat caagtagagg acaattaaat
    19681 cctggatgtc caccaataaa gtaaggcatg accttgctag tttctttatt agacttcctg
    19741 caaaactaga atcctagttc atgattgata ataccagcac tcaaattcat tcgtaatccg
    19801 aagcgtttac gatgatttcg ataggttgtt gaaaacattt taaacgtttt tactttggca
    19861 aagatgttct caaccttgct tctctcctta gatagcgcat ggttataggc tttatcttca
    19921 gctattagcg acttgagttt gctggattta cgtggagttt gtacttgagg atatatcttc
    19981 atgagtcctt gataaccact gtcagccaag attttaccag cttgtccgat atttctgcaa
    20041 ctcattttga acaacttcat atcatgacaa tagttcacag tgatatccaa agaaacaatt
    20101 ctcccttgac ttgtgacaat cgcttgagcc ttcatagcgt ggcatttctt tttaccagaa
    20161 tcattcgcta attctttttt taggtcgatt gatttgtact tccgtcgcat caatcattac
    20221 cgtgtcctca gagctgagag gagttcttga aaccgtaaca ccactttgaa caagagttac
    20281 ttcaacccat tggctccgac ggataaagtt gctttcgtga ataccaaaat cagccgcaat
    20341 ttgttcataa gttcgatatt ctcgcactat tgaagagtgg ccataagaag gtcttctagg
    20401 cttaatttag gttttcgtcc accttttgcg tgtttaagtt gataagctgt ttttaataca
    20461 gctaacatct cttcaaaagt ggtacgctga acaccaacaa gacgcttaaa tcgtgcatca
    20521 gttagttgtt tacttgcttc atcattcata gaactactat accatatttt gtttcgcagg
    20581 aagtataata ttgtcaaata ctggaacgct cattgctggg atacagaata agattggacc
    20641 agcttcgata actgggatac ctggttcaaa accaaggtct gttgcagcga ttggtgtaaa
    20701 gatatcgtaa cctttcataa ggtcttcgtt tacatctttc accatgactg catcacagtg
    20761 aacatcataa ccacggtttg aaagttcttc ttctagagca cttttaattt ggtgacttga
    20821 gttaacacct gcaccgcagg cagcaagaat tttaatcatt tggatttcct ccgattttat
    20881 tttttaatag acaagattaa gcggttgctt cagcaatgta agcataaagt ttttctggtt
    20941 cagaaatttt tgataggtct tcaagataac catttcctgt gaaaaagtcc atcaactgag
    21001 ccagaatatt tgtttgactt gaacttgaat tattgatgat aaagaagagc aaggatactt
    21061 ctacttcctt acctggcgca atcatattat ggaaagtcac cggtttctct aatcgaacga
    21121 ccacaacttt ttcagccaga ttgtgaacaa tatctgtgtg aggaatcgct acatttggca
    21181 agtcctttcc tagaaattcc atatctaaac cagttggaaa tgacttttca cgcgtgatca
    21241 aggcttcacg ataagtagga gtgacaattt ctcgttcttc caacaagctt gctacctgat
    21301 caaa
//
LOCUS       DBJKQU010000032        21160 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.032, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000032 DBJKQU010000000
VERSION     DBJKQU010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21160
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.032"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..304
                     /locus_tag="ACSUUC_001379"
     CDS             <1..304
                     /locus_tag="ACSUUC_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HHQ8054577.1"
                     /translation="PMTYEETMTSDFFEAWFQKFLLPTLTTPSVIIMDNARFHRMGKL
                     ELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            204..650
                     /locus_tag="ACSUUC_001380"
     CDS             204..650
                     /locus_tag="ACSUUC_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHQ8054578.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCPALVSIDYINCLSETTD
                     KNWHKSDRIFVTNIGKPVHSSILSKSLQRANERLKKPIPKHLPPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTQVTKNMKDEAINVLDKVMKKIF"
     gene            complement(788..2092)
                     /gene="eno"
                     /locus_tag="ACSUUC_001381"
     CDS             complement(788..2092)
                     /gene="eno"
                     /locus_tag="ACSUUC_001381"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HHQ8054579.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2256..2702
                     /locus_tag="ACSUUC_001382"
     CDS             2256..2702
                     /locus_tag="ACSUUC_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HHQ8054580.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2699..3814)
                     /locus_tag="ACSUUC_001383"
     CDS             complement(2699..3814)
                     /locus_tag="ACSUUC_001383"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HHQ8054581.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENRYKIPEGVQIHILADVVSPLCGYQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3823..4152)
                     /locus_tag="ACSUUC_001384"
     CDS             complement(3823..4152)
                     /locus_tag="ACSUUC_001384"
                     /inference="COORDINATES: protein motif:HMM:NF019887.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HHQ8054582.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAKEVLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4097..4468)
                     /locus_tag="ACSUUC_001385"
     CDS             complement(4097..4468)
                     /locus_tag="ACSUUC_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HHQ8054583.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4527..5960)
                     /gene="glgA"
                     /locus_tag="ACSUUC_001386"
     CDS             complement(4527..5960)
                     /gene="glgA"
                     /locus_tag="ACSUUC_001386"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - alpha-1,4-glucan
                     glucosyltransferase (UDP-glucose donor) activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HHQ8054584.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5957..7096)
                     /gene="glgD"
                     /locus_tag="ACSUUC_001387"
     CDS             complement(5957..7096)
                     /gene="glgD"
                     /locus_tag="ACSUUC_001387"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HHQ8054585.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAEMFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GKGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7086..8228)
                     /locus_tag="ACSUUC_001388"
     CDS             complement(7086..8228)
                     /locus_tag="ACSUUC_001388"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HHQ8054586.1"
                     /translation="MKNKMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGAVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8218..10146)
                     /gene="glgB"
                     /locus_tag="ACSUUC_001389"
     CDS             complement(8218..10146)
                     /gene="glgB"
                     /locus_tag="ACSUUC_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HHQ8054587.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFVERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            complement(10522..11946)
                     /locus_tag="ACSUUC_001390"
     CDS             complement(10522..11946)
                     /locus_tag="ACSUUC_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HHQ8054588.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(12491..14770)
                     /gene="pulA"
                     /locus_tag="ACSUUC_001391"
     CDS             complement(12491..14770)
                     /gene="pulA"
                     /locus_tag="ACSUUC_001391"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HHQ8054589.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLTPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGTYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(14882..16840)
                     /gene="ligA"
                     /locus_tag="ACSUUC_001392"
     CDS             complement(14882..16840)
                     /gene="ligA"
                     /locus_tag="ACSUUC_001392"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HHQ8054590.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASKLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(16933..18111)
                     /locus_tag="ACSUUC_001393"
     CDS             complement(16933..18111)
                     /locus_tag="ACSUUC_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHQ8054591.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(18191..19054)
                     /locus_tag="ACSUUC_001394"
     CDS             complement(18191..19054)
                     /locus_tag="ACSUUC_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HHQ8054592.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(19057..20958)
                     /locus_tag="ACSUUC_001395"
     CDS             complement(19057..20958)
                     /locus_tag="ACSUUC_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HHQ8054593.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         6385 a         4656 c         3761 g         6358 t
ORIGIN      
        1 tccaatgact tacgaagaga cgatgacgag cgactttttt gaagcttggt ttcagaagtt
       61 tctcttacca acattaacca caccatcggt tattattatg gataatgcaa gattccatag
      121 aatgggtaag ttagaacttt tatgcgagga gtttggtcat aaacttttac ctcttcctcc
      181 ctactcgcct gagtacaatc ctattgagaa aacatgggct catatcaaaa agcacctcaa
      241 aaaggtatta ccaagttgca atacctttta cgaggctctt ttgtcctgct cttgtttcaa
      301 ttgactatat aaattgtcta agcgaaacaa ccgataagaa ttggcacaaa agcgaccgta
      361 tttttgttac caatatagga aaaccagttc atagttctat cttgagcaag tctctccagc
      421 gagcaaacga acgccttaaa aaaccaattc ccaaacatct gccccctcac atcttcagac
      481 acaccactat tagcatctta tcagaaaata aaattccttt aaaaacaatc acggacaggg
      541 ttggtcattc cgactctgaa gtcactactt ccatctacac ccaggtcaca aagaatatga
      601 aagatgaagc aatcaatgta ctggataaag ttatgaaaaa gattttttaa aaagttttgt
      661 cccttttttg tcctctaaat acaaaaatag cccttcggat aaaatccgag gggctagaaa
      721 cgttgttaaa tcaacggccg aacttttgaa tttcatggtt cgggataaaa tagttcactg
      781 aactatttta ttttttaagg ttgtagaatg atttcaatcc acgatattca gctacttcac
      841 caagttggtc ttcgatacga agcaattggt tgtatttagc gatgcggtct gtacgtgaaa
      901 gtgaaccagt cttgatttgt cctgcgttag ttgcaactgc aatatcagcg attgttgaat
      961 cttcagtttc acctgaacgg tgtgatacaa cagcagtgta accagcttct ttagccattt
     1021 cgatagcttc aaaagtttca gtaagagtac cgatttggtt aactttgata aggattgagt
     1081 tagcagcacc ttcttggata ccacgtgcaa ggtagtcagt gtttgttacg aagaagtcgt
     1141 caccaacaag ttgtactttc ttaccaagac gttcagtaag agctttccaa ccatcccagt
     1201 cgttttcatc cataccatct tcaatagtga tgattgggta tttgttaacc aattcttcaa
     1261 ggtagtcgat ttgttctgca gatgtacgaa cagcagcacc ttcaccttca aatttagtgt
     1321 agtcgtaaac tttacgttct ttatcgtaga attctgatga agcacagtca aatccgataa
     1381 atacgtcttt acctggtaca tatccagcag cttcaatcgc agcaaggata gtttcaacac
     1441 catcttcagt tccttcgaaa cgaggagcga atccaccttc gtcacctacg gcagtttcca
     1501 aaccacgtga tttaaggatt ttcttaagag cgtggaagat ttcagcaccg taacgaaggg
     1561 cttctttaaa tgttggcgca ccaactggca agatcatgaa ctcttggaaa gcgattggag
     1621 cgtcagagtg agaaccaccg ttgatgatgt tcatcattgg agttggaaga actttagtgt
     1681 tgaatccacc aagatagctg taaagtggga tttcaaggta gtcagcagca gcacgagcta
     1741 cagcgataga cacaccgagg attgcattcg cacccaattt acctttgtta ggagtaccgt
     1801 caagtgcgat catagcacgg tcaatagctt gttgatcacg tacatcgtag ccaatgatag
     1861 cttcagcaat gatgttgttt acgttgtcaa cagctttttg tgtaccaaga ccaccgtaac
     1921 gagatttgtc accgtcgcga agttcaactg cttcgtgttc accagtagaa gctcctgatg
     1981 gaaccatacc acgtccgaaa gcacctgatt cagtgtaaac ttctacttca agtgttgggt
     2041 taccgcgtga gtctaggact tcgcgagcgt aaacatcagt aataattgac attttttact
     2101 ctccttatga gttaaatttt ttacacctct ataatacctt aaaacccctc ctttttcaag
     2161 aaaaaacgtt atctttgtgc aacttttcct taactttata aagtaatcgc tttcttttgt
     2221 ctgttttatt ctaactttta tgatatactg ttttcatgac agatttatca aaacaattac
     2281 ttgaaaaagc tcatggtggg ttaaaaataa atccggatga gcaaagacgc tatcttggta
     2341 cttttgagga aagagttctt ggatatgtag atattgacac agcaaatagc cctcagttag
     2401 aaaaaggctt tttatttatt ttagaaaacc ttcaggaaaa agcagagcca ctatttgtga
     2461 agatttcacc aactatcgaa tttgataagc aagttttcta cttaaaagaa gcaaaagaaa
     2521 ctgatagtca agccaccata gtatctgaag agcatattac ttctcctttt ggcctggtta
     2581 ttcatagcaa tgcaccagtt caagtagaag aaaaagacct tcgacttgct tttccaaaac
     2641 tttgggaagt taaaaaggaa gaaccagcca aaacatcctt atggaagaaa tggtttagct
     2701 aaatcttgca catatttaat aagtgcccaa tattggcagc cgtgcgctcc agatagagac
     2761 tggcattttt caaactatct tctaaaggtt cacttttctc caaaatagaa aagacagctt
     2821 ggatattttc aaatggtagg ggaggtaaat cttcagcaag actaccgcaa atagcaataa
     2881 caggaactcc aacaggggtt ctttttgcaa cacctatagg cgctttccca gcaaagcttt
     2941 gactgtcaag tcttccttct ccaacaacaa ccaagtcagc atctgaaact ttcttatcaa
     3001 agttgattaa gtccaagcag gtatcaattc cagacacgat acttgcctga gcaaaggcac
     3061 acaaaccacc agcaaggcct ccacctgctc ctgctccttt aatttctaat gttgcaggtg
     3121 agaatttttc ataaaaatct tggatcgcct gatctacgac tgcaaacata gtcggatgta
     3181 gacctttttg attgccaaaa gtgtaagtcg caccttgata accacataag ggactcacga
     3241 catctgctaa aatatgaatt tgaacacctt caggaatttt atagcgattt tctgttgaaa
     3301 cagaagctaa gtttaataag gattgaccgg aagcaggcaa gacatttcca tccctatcat
     3361 aaaattgata acctaaacca gcagcaatcc ccagtcctcc atcattactg gccgtgccac
     3421 caacaccgat ataaatatct ttaatccctt tagaaatgag atggagaatc aactctccaa
     3481 taccacaagt ttggatttga agtggatttc gtttctctag cggaattttt ccaagaccaa
     3541 ccaagtcagc tacttcaaat agtgccagtt cccctttttg aaaatagcgc atggcttctt
     3601 tttgtccaaa agggtctgtc acttggatcc atttttcttt taggtcaaga gaatgtcgga
     3661 tagcatctac agtaccttct cccccatcac caacagggca gaggagacat tctacatctg
     3721 ctatcgattg ttggaagcct ctttttattg cttcagctac ctgttgagct gtcaagcttt
     3781 ccttaaacga atccggtgca attacaatct tcatattttc cctcattcta aacagtcaat
     3841 caaaggaaga acttctaaaa aatccctctt gtcaacatga tgtggtattt cttttttgag
     3901 cacttctttg gcacaaaagg cgattcctaa ctccgccgac ttcaacatta atagattatt
     3961 gaccccatca ccgattgcca ccgttctttc tttagaaagt tttagtttct ttctccattt
     4021 ttccagagtt tcttttttga cctggggact tataatttgt ccaactaatt ttcctgttaa
     4081 aagaccttct ttgacttcaa gctggttggc agtgaaatag gcaataccaa gggattttgc
     4141 taatctctcc aactattggt gtaaatccac cagacaccag accaactagg atgccattct
     4201 tttggagaat agagatgaac tctgggacat ttagcgatag atgaattgag ttgaagacgt
     4261 tatcaaagac caaaatagga agaccttcca acaaggacac tctttttctt aaactgcttt
     4321 caaagaccaa ctctcctcgc attgctcgac ttgtaatctg cgaaatttcc gcctcatgac
     4381 ctgcctctct ccctaaaaga tcaatcactt cttctaggat taaggttcca tctacatcca
     4441 aaacacacaa gccttttact tgagacatca gttctcctct ctaaacagcc taaaaatcgt
     4501 atgaagtcat catacgattt tatctattaa ttaactaaac tatggtacaa gtcaaggtat
     4561 gacttgcagg ctgtatccca tgagaagtca ctctccatag cttgtttttg taggtttctc
     4621 caaatgtctg gatggtttct atacaagtcc aatgctgttt ggaaagtcca atttaaccaa
     4681 taaggagata gattgtcaaa gctaaagcca gtaccgcttc cttcgattgg attgaaagcg
     4741 cgaactgtat ctcgcaagcc tccaacttca tggaccaatg gcaaggttcc ataacgcata
     4801 gccatcattt gagacaagcc acacggttca aaacgacttg gcatgaggaa gaggtcacaa
     4861 gcagcgtaga tttcctgagc aagtttgaca tcaaaagtga tatttgttga tagcttgtct
     4921 gggtaaatct gagcaaacca tgagaaagct ccttcaaagg ctggatcgcc agttcccaaa
     4981 agaacaatct gaacatcttc ttgcaagata tggtgaagac tttcgaccac cacatcaaaa
     5041 cctttttgac gtgtcaaacg agaaacaatt cccaccagtg gaacgtctgc tctaacaggc
     5101 aagccaactc tttcttgcaa ttttgcctta tttttggctt tcccagacaa atcttcctga
     5161 ttgaaatgat agtctaaaag agcatccgtc tgaggattat aaagatcagc atcaatccca
     5221 ttcacgatac cagatacttt accagactcc attttaagaa tctgatccaa attacatcca
     5281 aactgactag tcataatttc atgagcatag ctaggtgaaa cggttgaaac acggttcgca
     5341 tagagaatac ctgccttcat ccagttcaga cagttgttcc atcgaagggt gccatcagcg
     5401 taacgttcaa ggccaactcc aaacaaatca cccaacattc cttctgaaaa ttgtccttgg
     5461 aattctaaat tatgaatggt taaaactgtt tcaatgtcct cataggcttg aatccaacgg
     5521 tatttttcct tcaacaagaa aggaatcata gctgtatggt agtcatgaac atggagaaga
     5581 tcaggaataa agtcaatcct ttccatagcc tcaatggcag ccagttggaa aaaggcaaag
     5641 cgttctccgt catcaaaatc accgtaaaca tgaccacgga agaaataata ttgattgtca
     5701 ataaagtaga aggttacacc atttaatact gttttcttaa ttccacaata ctgtctgcgc
     5761 caaccaacgc tcacctcaaa atgaagcaca tcttcaatct gatttccaaa tttagcctct
     5821 accatatcat agtagggtaa aatcactgca acttcgtgcc cagcttttac cagtgatttt
     5881 ggaagagcgc caatgacgtc tcccaaacca cctgtttttg aaaaaggtgc accctctgct
     5941 gctacaaata aaattttcat gaatgaatat cctctgttac tttagcacct ttcttaacca
     6001 caactggatg ttctgcagtt cctcgaatca caacaccagg ctcaacttca acccctttgt
     6061 ccaagatagc atattcgacc tgagcccctt ttccaataac aacacgaggg aagagcaggc
     6121 tatctttaac caagctatcc ttatggacat gaatattacg tgatagaaca gaattagcta
     6181 cttgaccttc aataatacta ccagaggcaa actgagaagt gcttacctta gatgtattag
     6241 catagtaagt tggctcttcg tttttgacct ttgtataaat cttttggttt ggtgagaaaa
     6301 gagaatagaa tttttgtgat tcaagcatat cgatattcgc ttgataataa gatttaacag
     6361 agtgaatatt ggctagatag cccgtgtact cgtaggcgaa agctccctct tttacagcca
     6421 aatcccgtaa aacatagcgc aatttctttg gatgttcttt tttagcttct tcttccaagt
     6481 gttcaatcaa ccaaggtgta tcaacgacaa agatatctgt agacatattg aacatttcag
     6541 ctgttgactt gctatcaaag agtttatgag aaagaacatg gtctgtttca tctacatcca
     6601 agattgcatt tacttctgaa atatctttct tagctagttt tttataaact acagtgatag
     6661 gctcttttgt tgtactatgt aggtggaaaa cttggttcaa atcaatgtta ataagaacat
     6721 cgcagttgag ggcaaccgtt tggtttgagc cagaacgttt caaataagta agaagctgtt
     6781 ggtagtattc ttttccaact gtactacttt ctacacgggt attgtaaatt cctagatagt
     6841 aatgactaag aagggttgat aagccccact cgcgtcctga acgaatatgg tcaaatactg
     6901 agctgatatt atcctgctgg aaaataccaa agacactacg aacacctgca ttagcaaggc
     6961 ttgaaagtgg gaagtcaatc aaacgatatt tcccaccaaa tggcaaactt gctactggac
     7021 ggtggtccgt caatgtcgac atattgtgaa aaccaactgt atttcctaaa atggcagaat
     7081 atttatcaat cttcatctgt tgctaccccc actacttcat tatatcctac aacttgtact
     7141 tcatctgttc catcaatttc gacaccgtca gaaataatcg caccttcacc aataatggca
     7201 cgtttaatct tagctccttg accaatgata gctccactca tgataactga atcaaggact
     7261 tccgctcctt cgcgaacttg cgcgcctgtt gaaaggatag aatgtttaac agctccatca
     7321 acgaaacatc cgtctacaac taatgagtct tccacatgag catttgcccc gaggaagttt
     7381 ggtggtgaaa tcaagtttct tgagtaaatc ttccattgac ggttacgact atccaaggca
     7441 ttttctggag aaatatactc catgttcgct tcccaaagtg actcaatagt accaacatct
     7501 ttccaataac cactaaattc gtaagcataa acactttcac ctgactcaag gtaatttgga
     7561 atgacatttt taccaaagtc tgacatgcca accttgctct tttcagcagc gactaacata
     7621 ttacgaaggc gttgccaatc aaaaatgtag attcccatag aagcttttgt agatttaggt
     7681 tgagctggtt tttcttcaaa ttcaacaata cgattgttag catctgtgtt catgatacca
     7741 aaacggcttg cttctttaag agggacgtct aaaactgcta ctgtcaagct ggcattatta
     7801 tccttatgag actggagcat atcatcatag tccattttgt agatgtggtc cccagacaaa
     7861 atcaagacat actcaggatt gacactgtcg atatagtcga tattttggta aatagcgtga
     7921 ctagttccct caaaccaacg atttccttca cttgcagaat aaggttgaag aatagagacg
     7981 cctgaattaa taccgtctag tccccagctt gaaccattcc caatatggtt gttgagagca
     8041 agtggttgat actgtgtaac gaccccaaca ttatgaatcc ctgagttggc acagtttgat
     8101 agggcaaagt caatgatacg gtagcgccca ccaaattgca cagctggttt tgcgatgctt
     8161 tgagtgagtt taccgagacg agttccttgc ccaccagcaa gaatcaaagc taacatttta
     8221 tttttcattt tctactcctt tttggttttt atttgtgacg gttttagtag atttcaagcg
     8281 acgtttgatt ttccatacac ttgctcccat agccggtaga gtaaaggtta aggtctgctc
     8341 ataatctttc cataggcctt cttgcgtttg aacagtttga ttatgttctt tccaaacgcc
     8401 tccccactct tccaactcag tattccatac ttcttcgtaa attcctgcaa cgggtagtcc
     8461 gattgtaaaa tctttccgct caacaggtac catgttaaag atacagacta acatttctcc
     8521 ctttttaccc ttacgaataa aggaaagaac actctggtct cgattatccg catcaatgat
     8581 ttcaatacca tcatagctgg tatcgatttc ccacagacag cgatgatctt tgtaaaactg
     8641 gtttagctga gaagtgaaat acttcatctt agcattcatt gggtcttcta ggttagacca
     8701 ttccaactgt tcttcagatt tccattctag gaattgaccg tattcgctac ccatgaagag
     8761 caatttctta ccagggtgac aaatttggta cgtatagaga ttgcgcaagc ctgcgaattg
     8821 attgtaacga tctccccaca tcttatgcat catactcttc ttgccatgaa ccacttcatc
     8881 gtgcgagaat ggcaagagat aattctcctt gaaaacatac ataaagctga aagtcaccag
     8941 gttaaagtca tatttacgat aaatcggatc ttcttcgtag aaacggagga tatcattcat
     9001 ccagcccatg ttccatttgt agtcaaatcc tagaccacca atctctttca ttcccgtaat
     9061 cttggtcgca gacgaacttt cttctgcaat catcatcaca tctggatatt ctaacttaat
     9121 aacttcattc aagcgttgaa gaaaataata accttcatag ttaagatttc cgccatcttt
     9181 attaggtgtc catggagcat tatcatagtc caaatagagc atgttgctaa cagcatccac
     9241 acgaatacca tccaaatgat agacatcaat ccaatgctta atgcaagaaa ttaagaagga
     9301 ctggacttca ttttttccaa ggtcaaaatt aagggcaccc caaccatggt tatgagcctt
     9361 attatggtct tggtattcaa aagtcggtgt cccatcataa taggctaagg catcatcgtt
     9421 gatggtaaag tgacctggta cccagtccac aataacccca atattatggg tatgacactc
     9481 ctcgacaaaa tcttgaaact cctctggtct gccataagca tgctctaaag cgaagtaacc
     9541 cataagctga tacccccaac tcaagcccaa aggatgggac atcaagggca taaactcaat
     9601 atgagtatag ttcatttcaa cgagataagg aatgagttca tccttgagct gggcaaaact
     9661 ataaggactg ccatcaggat ttctcttcca agagccagca tgaacctcgt aaatattgac
     9721 aggacgttca acaaagcccc aacgttttct tcgtgccagc caaagtccat ccctccattt
     9781 cttatcagga agctctgtta cgattgcccc tgttcctgga cgagcctcat acctgacagc
     9841 aaaagggtca atcttcatca gttgatgacc attttgacgt gtgacatgat atttgtaaat
     9901 atgcccttct tgagccatat tggtaaagac ttcccagacc ccaaagtcat ttcttaccat
     9961 tggaatctga ttttcaatcc agttggtaaa atcaccaacc aagtgaacag cctgagcatt
    10021 aggtgcccaa acacggaagg tatagccatg ctctccattt agttcttccc tatgtgctcc
    10081 tagataatgt tggagataaa aattttcacc cgtcataaag gtttttaatg cttctctatt
    10141 atccatatac tccccttctc ctgtaagcgt tttctatgtt tttattatac taccttttta
    10201 gagaagattc aagtaaatta ctatacttct ttaattattt tgaaaatcta caacaagttc
    10261 acttactcgt tcaattgtaa atcaatattt tttcaaaaaa ttgcgaaaac gcctttcttt
    10321 ttctactata gtgaaatgaa ataaaacatg cgcaaatcga tcaggacagt caaatcgatt
    10381 tctaacaatg ttttagaagt agagctgtac tattctagtt tcaatatact ataataccaa
    10441 aaagttcgta ttttttctat aattattatt attttatagc aaaaaaataa aaccaggaaa
    10501 acaatttcct gattttacac gttatttcac atcaaaaaca atggatttga catttgtcat
    10561 cgcttcaatg ctatatttaa ttccttgcac tccagctcca gaacctttga caccaaggaa
    10621 tgggaaatta tctggaccac gctgggtttt attattaatg tggactgtac ctacttcaag
    10681 tttttcagca atttcaaagg cttttttgaa atcatttgta aagactgatg attgaaggcc
    10741 gaattcagat tcgttggcaa aggcaatagc ttcctctaca ctagccacac gaatgattgg
    10801 taaaacagga ccaaatggct cttcccatgc cactttcata tcttttgtaa cttggtcaaa
    10861 aagcactggc cagaggagat tgccctcacg tttgattggt gtaagagcct gagcctcttt
    10921 ttcttgtgca tcctcaatca agccccaaat gaagtcggct gaagcattgt caataacagg
    10981 tgtaatatca gcattgtcaa atggatcacc aactgttaat ttagaaactt cttcctgaag
    11041 caaagtagct aatttatctg ctacactttc gagaacaatg acacgtttaa tggccgtgca
    11101 acgttgtcct gagtagctaa aggctcccgc aacaatttgc ttggcagcat gttccaaatc
    11161 tgcatcttct agtacaagag ctgcatcttt cccaccaagt tccaacatga taggacgcat
    11221 accagctaaa cgaccaatac gttctccaat aggggttgaa cctgtaaagt tgatgaagtt
    11281 gacttctttg tgctcaatga tataatcccc aatttctgaa ccacgacctg taatggtgtt
    11341 gaaaacacct gccggaatcc ctgcttcttc aaatgcttta gccaacaaga gtccagaaat
    11401 ggaaccttgt gttggtggct taaacatgac cacattccct gcaatcaagg caggtgcaat
    11461 tttagaagca gataaattaa ctggataatt aaagggagca atcgctagca cgataccaac
    11521 tggttcacga cggacaacag ccagtttgtt tttacttgct gcctcaaaac caccaccttc
    11581 cattgcttgt ccagtgatac ggagaccttc ctcagcagca taacgaatca agtctgctgt
    11641 acgcactact tctccaattg ctgctttaat cccttttgct acttctttgg caaggatagt
    11701 accaattttt tccttatcgc gttctaaaat agctgctgtt ttatgcaaat aagccgcacg
    11761 ttcaattgct gataaagctc gccatgctgg cagggctgca cgcgcagctt gcatagcctc
    11821 atcagcttca gtctgagtca tggctggaac tgtacccaat tcttcttgat tgattggtga
    11881 ataaatcgta atttcttgtt cagatgattt ccattttcca tttactaaat tctgatatct
    11941 tgtcaaattc ttgtcctcct gaaaatgatt aagatatatt ttaccaaatt ttcagaaaat
    12001 cacaaccctt tttgcaaaat ttttgagatt attttcacaa gcttgatttt tcaaagtata
    12061 ctcaataaaa ataaaaaaaa tccactacat caaggcgaga ctaatgtggt ttgaagaaat
    12121 tttcgaagag cgtgaatgag tatcatctat agtaaaataa aaaaactgaa caatttggtt
    12181 ggggacagtc aaaccaattt ctcacaatgt tttagaaaca agggtgtgct attccaattt
    12241 caggctacta taactgtcat agattgctga aacaaagtct aggtaaaagt cttcataata
    12301 aaaagacccc ctatcaagtg ttcaaaaact ttgataggag gtcttgtttt gtgaaaatat
    12361 ttatcaaatt ttctatacaa gtgagctgtt agccaggttc tttctattct ttcaatttca
    12421 atgaatggat tttttaccaa tactcataac tgggaatttg tctgtgtaaa aatagcgaga
    12481 tagatggtat ttataaaaca ctcaagacag ctagactaat atcatttaaa acattatctt
    12541 cttttgagcg actgttggtt accaacatag ctaaatttcc tgcattttca aattgatagg
    12601 gttctgattt agcattcaca actaccaaga ggtgttcttt gccgtgaact tcatagataa
    12661 ggcagccgct atgttcaatc gcagaatgca caaagacatg atggtaaatt tcatcatagc
    12721 tagagtaaga aaaggcacca gtttttgtct tcaatcggat gacttgacgg ataaactcaa
    12781 tactgtcttg acgctcatta atcaagttcc agttcacttg gttcacactg tcaggagcat
    12841 tatagctatt catcgcacgc tctctatcat catgggtcaa ctcaccattt tcaccagtcg
    12901 caaccagttt ggtacgacca aattcttgac cgatttccat aaaggccatc ccctgcatga
    12961 gcagattcat ggctgtggca gtttcgacct tgcgcatgat ttgctctgaa ctttggtctg
    13021 gatgaagggt tgccaataaa tcgtgaagat tgtaattgtc atgggcttct acatagttaa
    13081 gcacctgatt tggatgtgta taggttccta attcacgact tcctaggatt gctttagcta
    13141 gaattggctc tgtcgcagca ccactgacaa aacctgactt gatagcacca taaacttctc
    13201 cccctttgac agcatcgcgc tgattgtcat taaagaaacc aatatttggc atctggtagg
    13261 cattgtcctt cttggcctta tcataagggg taagacctgt tcccatatcc catccttctc
    13321 catagaggat aatgttggag tcgatttcat ccaagctttg acgaatcatc tgcatggtct
    13381 tgacatcatg aatccccatc aagtcaaaac ggaagccgtc aatattatat tcctgcaccc
    13441 agtatagaag agaatcaatc atatacttgc gaaacatttc gtgttcactg gctgtttcat
    13501 ttccaacacc cgttccattc tggaaggtac catctggatt catacgataa tagtaatcag
    13561 ggactgttgt ttggaatggt gcatcaacaa ctgagaaggt atggttatag actacatcca
    13621 taatgactcc aatacccgca tcgtgataag cttgaaccat caccttcaaa tcacgaatga
    13681 cctgagctgg atcatctgga ttagttgaaa aactagtttc tggcgcgtta tagttttgtg
    13741 gatcataacc ccagttgtag gttacatttc catcctcatc gtattcttta tgacggtctg
    13801 caattggttg caattgaaca taattgtagc ccagcttctt gatgtaatca aaagcagttg
    13861 actggccgta ttggttaact gttccagcct gagcagcacc caagaaagtt cctcgaagat
    13921 gttcatctac acccgatgta ggtgatttag tcaaatcacg aatgtgcatt tcacagataa
    13981 ctgccttaca tggattttcc aagcgccaag tagcctccga accgtgctta acctcgaagt
    14041 tttcaacttg cttttctaca tggctcagaa tagctgaacg tttgccatca gggctggtcg
    14101 cgattgtata aggatcacgt gtcagtgttt ggtgatgagg gaattggact tgatactgat
    14161 aagtcttacc taccaaatct tcttcaacat ccaaactcca gacaccgatt gtattgtcct
    14221 tatgattata agagtagcta ttgcctcttt tcatctcaaa agtcttccaa acgggtgcat
    14281 cattagcagc tgattcataa acgacaactt gcacttctgt cgctgtaggt gaccagaggg
    14341 aaaaatgagc ctgattgtcc tctacacggc aacccaattc tccttggtaa ccccaatgat
    14401 gatcaaaact agcactgtta atggccttat caaaggcaaa aggattttga tttttataga
    14461 aaggactggc aatagcagga ttttcagagt aataaatcct atcatcgcct tccaaaatcc
    14521 agacctctgt caatagggga tagtgattaa aacggataga atattcttta ctagtttgac
    14581 ctgtatgaac cacaaaattc aagctttcta taacatgtga acttgggtgt tcaaagctaa
    14641 ataaagctcc aaaataatct tctttgtagg ttagcaaatc aattcgttga tcctgacttt
    14701 ttacaaagga gcaagtgtca tattctccat tcttacgatg gtaatgaatg cgcatagggt
    14761 agttatacat tttttatttt tcctttttac tttgtttcta tttcactaat aaatttttgt
    14821 caatctcgtc tcaattaaca gacatagtca tattctctaa actctgtttt taaacgatcc
    14881 attacaaact ttctagccat gcctcatctc tgacctggat accaagttct tgtgcttttt
    14941 gcagtttact tccagcgtct gcacctacca cgacgaggtc ggtcttttta gaaacactac
    15001 ctgtcacttt ggcacccaga ctttcgagtt tacttttagc ttctgagcgc ttgagtcgtt
    15061 ccaattttcc tgtcaatacc acggtcaaac ctgacaaggc cgcatccgct actaccgtct
    15121 gtcctttata gtccagattg accccagttt ctttcaattc tctgagcaga atttcagagc
    15181 cttctgtcgc aaaataagtc tgaagacttt tggcaatcac gccacctaga ctttcaatac
    15241 tagccacttc ctctgaatct gcctgataca gattttcaat tgaatggaaa tattgaagta
    15301 aaagcttact agccttgctt ccgacatgac gaattcccaa accaaataag agcttctcgg
    15361 cagaattttc ctttgatgct tggatagcct gatacagttt agcagcggac ttttccttaa
    15421 ccccctctaa aaggaggaaa tcctcttctt gcaaacgata aatatccgcc acatccttga
    15481 ctaaattagc agcaaaaagc ttctcaacaa tagatggacc aaggcctgta atattcatag
    15541 catcacgaga agcaaagtga atcaagcctt ccatgatttg agcagggcaa cgcggattga
    15601 tacaacgtag ggccacttca tcttcaaagt gcaacaagtc agagttacaa cttggacagt
    15661 ttgtagggat atctagtttt tcttcagaaa cccgtttgga ctctaccaca cgtaaaacgg
    15721 cagggatgat gtcaccagcc ttatatacaa tgaccgtatc gtcttttcgg atatcttttt
    15781 cagcaatata atctacattg tgcagggtcg cacggctaac agtcgtaccg gcaagttgta
    15841 ctggtgttag attagcagtt ggagttacaa caccggtacg gccaactgtc cagtcaactg
    15901 ataagagttg agcttctttt tcttcagcag ggaacttgta ggctactgcc cactttggag
    15961 ccttaacggt aaaaccaagt tcttcttgac ttgctaggtc gttgaccttg attaccactc
    16021 catcaatatc gtaaggcaga ttttcccgtt cctgtcctac ttcttggata aaattccaga
    16081 tttcatctat gttttcagcc aagattcgct taggattgac cacaaaacct agttgttcta
    16141 ggtacttcaa acccttttct tggctatcac gagttgaagg gctggcttct tgatagagaa
    16201 acgttgcaag attacgcttg gcaactactg ctgtatccaa ctgacgcaga gttcctgctg
    16261 ccgcattacg aggattagca aattcaggct ctccattttc ttggcgcact tggttaactt
    16321 ggtcaaagga agcgcgtggc atgtaacatt ccccacgaac tgtgatatct agttcttctg
    16381 gcaaagtcaa agggatgtcc ttaacacgct tgaggttttc tgtgatattt tcaccaattg
    16441 aaccatctcc acgtgttacc ccagcaacca aaatcccctt ttcataagtc agcgagatag
    16501 ataagccatc gattttcagc tcacaaatat aggtcggatg agccacttcc ttacgaacac
    16561 gcgcatcaaa agcatctagc tcctcacgtg aaaaagcatc ctgcaaacta taaagaggat
    16621 actgatgact gtatttttca aaaccatcta aaaccttgcc accaacacga tgagtcggac
    16681 tgtctgctag cacttgctct ggataagcag tttctaactc gaccaactca cggtaaaggc
    16741 ggtcatactc actgtctgaa accgagggat tatcgctggt atagtactca gtcgcatagc
    16801 gattgagcaa agcgactaac tcattcattc ttttattcat aagaccattt taccataaaa
    16861 caagccctcc tcacaaacga gaaggacgga aaaaacactt agtttgaaat tatttttgaa
    16921 actcaagcaa ccttatatca atttttcaaa atgagttcga acataaataa acgatataca
    16981 agacaagatg ataacaccac ttccaattat caggaaagaa gagagatgta cacttggcaa
    17041 gactgtcata aatccttttg caataggcat aaatagaata gctaaggtaa aaattgtact
    17101 cagtactctc ccaagaaatt cgctctcaac cttggtttgt acttgagtaa aaaagtgaat
    17161 attaaaaatc gtcataaaca attcacaaac taaatttcca gaaaaggaaa gaaaagttgg
    17221 aagtggtaat cccatcataa aaactccgac acctgtcaaa gccagtaaaa tcaaaagatt
    17281 ataaatatta gctttaattt tactagctag aagagcccca atgatggaac caatagcccc
    17341 catagttaaa atacttgcat aggctccttc tgatccgtaa agctgattcg aaaagggaag
    17401 tagaaattca aaagctgcaa aaaagaaatt aacgctggaa gctaccagca aaaggaagaa
    17461 aatttcttgc tgatgccaga tatagtgtaa cccatccttg atatctacaa aaatatctct
    17521 cccagtaaaa gcctttttct cttgaacttt tgcttcctct tttggaagga aagccactag
    17581 aacaaaagca atgaaaaaag tcagcgagtc tagcagtagc gtcatatgga gacttgcaaa
    17641 ctgtaaaaca aggaaggaaa gaacaggaga gctaacacct acaacctgca aaaccagctc
    17701 taggcgagaa ttatagatca caatctcatc tttctccacc acttcagtta tgatagcttt
    17761 attggctgtg cgagaaaagg caaaagcaat agcctgcaca atgttagcaa caatcaaagc
    17821 gccaatcatc cagctatcat tccttatgaa agaaatagcc agacaaagaa tcccacaaac
    17881 aagatctgcc gtcattaaaa tcttacgacg agaaaaacgg tctgaaataa ctccgccaaa
    17941 gggattgacg agaatagatg tgacgagctc agaaatctga tacattccta aaactgtctg
    18001 tcctatagtc cccatagaag ccaaccagac actatttcca taatcataga gcatatttcc
    18061 cattttattg atagccccac ggctaatcaa ctgcactgca tagcgattca tattaaagct
    18121 cctctcaaat tttgaaacta ttgtatcaaa accgaaagga gctttttatt ttttccctta
    18181 tttgggaaaa ttaacttttg acaaattttt cgtagtgttc ctgataatag gctacttgct
    18241 ctggaagacc taacacatca aaaatatgta tggcctcttg catctgctta cagccttctt
    18301 tacactgtcc tttttgatat aaggcaaaac cttttaaata atggaaaaca ttacgctcat
    18361 aaagcttaat acctttgtca ataatcttct ctgtataagc ctcaaaatag ttggcattat
    18421 aaaaagaaga atgctctaaa caatgctggt aacaattgag ggccaaaatc aaaactaatc
    18481 tcttatggcg actaatctct tggtaaaatt cctccctctc cataacttct ctaccaatcc
    18541 gagtgacata gtctacatcg tagaaactat agaggttacc gaaaagaatc aactcataca
    18601 tggtccattc ttctgttttg aagagataat ctgctacctt atccaaatca tcctgcttca
    18661 tatcataact cgcatctctt tgacaaatca gaccttgtag caaaatccag ttcagctcaa
    18721 aataaagggg agtcgtcgaa ctcttagact tttcaagttg ttctctttga agcttttgaa
    18781 aacctgcaat atcgtttgaa tagtaaagtg ggataatctg tgccatcata gacacatgtt
    18841 catgattgtg aaaattcctt gccttatcca tgaaattttc gattgttaca tgaatgttat
    18901 ccaaaatctc aaagaaacgg gagactgcca ggtcagactc cccaagctca aagcgagata
    18961 actgagaggt agagcaggat tcgcctgctg cttcctttaa agaataattt ccacttgttc
    19021 gaaattcacg aaatactttt ccaagatgtt ccatctttac acctgatctg ataattcttc
    19081 ccactcaagc atagcttctt cctgacgatg gctgattttg tccagctcag cctgtaattc
    19141 catgagtttg tcggcatcgt ttgtttccaa catttgttca gaaatggctt ggctttgact
    19201 ttctagctct tcaatttcag cttctagact ttcgatttgt cgcatgagtt tgcgaacttc
    19261 tttttgactt tctttctggg cctgatagtc attgactgga cttgcttcct ttgcttgatt
    19321 gctagttgaa gcttcctcag tctgactcat ttctgctgtt gctttcttct caacatagta
    19381 gtcgtaatct ccaaggtaga gagttgaacc attctcagac aattccaaaa catgagttgc
    19441 cacacgattg ataaagtaac gatcatgact gacaaaaagc aaggtaccat caaagtcaat
    19501 caaagcattt tccaacactt ccttgctatc aatatccaag tggttggtcg gctcgtcaag
    19561 gatcaggaag ttgttgtttt ccatagacaa tttagctaaa agcaaacgag ctttttcgcc
    19621 accagatagc atgccgactg attttttaac atcatctcct gagaaaagga aggctccaag
    19681 acggttgcgg atttcaactt ctggtgtcag tttgaaatca ttccagagtt catccagcac
    19741 cgtattactt ggtgtcagct tgctttgggt ttggtcatag taaccaacct caacattagc
    19801 gccaaagcgc ttttcacctt tgataaaagg aatctggtcc acaatagact tgataaaggt
    19861 tgacttgccg ataccatttg gaccaacgat agcgacagca ttcatcttac gaagatctag
    19921 gttgataggt tgtgacaaga cttccccgtc ataaccaata gcagtatttt caacagtcaa
    19981 aacaacattg cccgacgttt tttcagactg gaaggtcatg ttggctgctt tcttgccagc
    20041 ttcaggcttg tccaaacgct ccattttttc tagttgttta cggcgagatt gagcacgttt
    20101 agtcgttgaa gcacgaacta gattgcgatt gacaaagtct tccagagcag cgatttcctt
    20161 ctgttgcttt tcatagtttt ttgcctcagt aactagcttt tgctccttca attcgacaaa
    20221 acgagagtaa ttccccacat agcgatccaa ggaatgcttg gtcaaatcta gcgtaattgt
    20281 cgcaaccttg tccaagaaat aacggtcgtg gctgacgata atgagggcac cgctatagtt
    20341 taccaagtaa ttctctagcc aggcgatggt ttcaatatcc aagtggttag ttggctcgtc
    20401 caagaccaag agattgggct tttcaaggag cattttggca agtgccaaac gagtattttg
    20461 accaccagaa agctcagcaa ttttcatctg ccacatagac tcgtcaaact tgaatccatt
    20521 caaaatcgct cgaatatcag cttcataggt aaagccacct gcttggcgaa aattctcaga
    20581 taagcggtca taatctgaca tcagtttatc caaatcctca ccagactttt cacccatctc
    20641 cagctccatc tgacgcagtt gtctctccgt ccgacgcaaa ttattaaaga catgaagcat
    20701 ttcatcgtag atggtatttt cagactcaaa acggctatct tgggctaggt aagacagaga
    20761 aatatctttt ttcttattga tttctccgct agttggctcc tcttctccaa ctaaaatctt
    20821 caaaagagta gacttacctg caccattttt cccaacaagg gcaatccgat ctcgttcatc
    20881 aacctgcagg ttgatattat cgaaaagaac ctctcctgca aaagaacgtt caattttatt
    20941 agcttgtaaa ataatcataa gagtagtata gcatgtttcc ctaaggcatt caagataatc
    21001 gtaagtcttt tagtacaact tttataacat aaaataaact aaattatgta tattttatat
    21061 tagattcttc actatcttgt tggattttct aaccagctaa tcttgtttca aatagttatc
    21121 gcacaagcct attatttaat tcttttcatt atttacgtac
//
LOCUS       DBJKQU010000033        21018 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.033, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000033 DBJKQU010000000
VERSION     DBJKQU010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21018
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.033"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(467..2098)
                     /gene="rlmD"
                     /locus_tag="ACSUUC_001396"
     CDS             complement(467..2098)
                     /gene="rlmD"
                     /locus_tag="ACSUUC_001396"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HHQ8054594.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2172..3146)
                     /locus_tag="ACSUUC_001397"
     CDS             complement(2172..3146)
                     /locus_tag="ACSUUC_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HHQ8054595.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVYAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3220..3834)
                     /gene="pmp23"
                     /locus_tag="ACSUUC_001398"
     CDS             complement(3220..3834)
                     /gene="pmp23"
                     /locus_tag="ACSUUC_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HHQ8054596.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3834..4808)
                     /locus_tag="ACSUUC_001399"
     CDS             complement(3834..4808)
                     /locus_tag="ACSUUC_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HHQ8054597.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4816..6072)
                     /gene="glyA"
                     /locus_tag="ACSUUC_001400"
     CDS             complement(4816..6072)
                     /gene="glyA"
                     /locus_tag="ACSUUC_001400"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HHQ8054598.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(6134..6565)
                     /locus_tag="ACSUUC_001401"
     CDS             complement(6134..6565)
                     /locus_tag="ACSUUC_001401"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8054599.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6567..7166)
                     /locus_tag="ACSUUC_001402"
     CDS             complement(6567..7166)
                     /locus_tag="ACSUUC_001402"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HHQ8054600.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7153..7992)
                     /gene="prmC"
                     /locus_tag="ACSUUC_001403"
     CDS             complement(7153..7992)
                     /gene="prmC"
                     /locus_tag="ACSUUC_001403"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HHQ8054601.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(7992..9071)
                     /gene="prfA"
                     /locus_tag="ACSUUC_001404"
     CDS             complement(7992..9071)
                     /gene="prfA"
                     /locus_tag="ACSUUC_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HHQ8054602.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9081..9560)
                     /locus_tag="ACSUUC_001405"
     CDS             complement(9081..9560)
                     /locus_tag="ACSUUC_001405"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8054603.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIVISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(9550..10149)
                     /locus_tag="ACSUUC_001406"
     CDS             complement(9550..10149)
                     /locus_tag="ACSUUC_001406"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HHQ8054604.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALTIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            10272..10454
                     /locus_tag="ACSUUC_001407"
     CDS             10272..10454
                     /locus_tag="ACSUUC_001407"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HHQ8054605.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10591..11964
                     /gene="mnmE"
                     /locus_tag="ACSUUC_001408"
     CDS             10591..11964
                     /gene="mnmE"
                     /locus_tag="ACSUUC_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HHQ8054606.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEEVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12011..12946)
                     /gene="dapA"
                     /locus_tag="ACSUUC_001409"
     CDS             complement(12011..12946)
                     /gene="dapA"
                     /locus_tag="ACSUUC_001409"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HHQ8054607.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     YPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13002..14078)
                     /locus_tag="ACSUUC_001410"
     CDS             complement(13002..14078)
                     /locus_tag="ACSUUC_001410"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HHQ8054608.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIVACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14664..14736)
                     /locus_tag="ACSUUC_001411"
     tRNA            complement(14664..14736)
                     /locus_tag="ACSUUC_001411"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14701..14703),aa:Thr,seq:ggt)
     gene            complement(14836..15345)
                     /locus_tag="ACSUUC_001412"
     CDS             complement(14836..15345)
                     /locus_tag="ACSUUC_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HHQ8054609.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15343..15439)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15468..15899
                     /locus_tag="ACSUUC_001413"
     CDS             15468..15899
                     /locus_tag="ACSUUC_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HHQ8054610.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15981..16358
                     /gene="mscL"
                     /locus_tag="ACSUUC_001414"
     CDS             15981..16358
                     /gene="mscL"
                     /locus_tag="ACSUUC_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HHQ8054611.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16400..17494)
                     /gene="hemH"
                     /locus_tag="ACSUUC_001415"
     CDS             complement(16400..17494)
                     /gene="hemH"
                     /locus_tag="ACSUUC_001415"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HHQ8054612.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVSISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            17649..18872
                     /gene="pepT"
                     /locus_tag="ACSUUC_001416"
     CDS             17649..18872
                     /gene="pepT"
                     /locus_tag="ACSUUC_001416"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HHQ8054613.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTTIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18908..19558)
                     /locus_tag="ACSUUC_001417"
                     /pseudo
     CDS             complement(18908..19558)
                     /locus_tag="ACSUUC_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            19559..19723
                     /locus_tag="ACSUUC_001418"
                     /pseudo
     CDS             19559..19723
                     /locus_tag="ACSUUC_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(19994..21006)
                     /locus_tag="ACSUUC_001419"
                     /pseudo
     CDS             complement(19994..21006)
                     /locus_tag="ACSUUC_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148462.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6093 a         4405 c         3918 g         6602 t
ORIGIN      
        1 ctttaaattc attggtatgc taattacaat atccattatt aaaatggata ctataagcag
       61 cacaccaact atttattttt tgagttttaa actttggtag aagtcttgaa ctccttatat
      121 ttacataact atttgcctct ataactatta tgacacgaaa ccaacaagca agttcaagca
      181 cctccatatc tttattcaaa tgaggactaa gatattcaca aactttatca taaacctctt
      241 tatctttttt cataaaaggg gcatacaact tagcaaattt atcctaaaat tttttgttgc
      301 ctttatcaat catttcaacg ctcctttaaa tataaaaatg atcctatcaa tctttatatt
      361 gagcctattt tctaattgat accttgcaag aaaggaataa tagctgttcc tataccaagt
      421 aggaatgtaa taaatgcaga aagtcatata ctgtcattct tttctattaa atcattttga
      481 agtgtctcaa agcatccatg atggcttctt ctttttcagg tgtacactgt ggaataattt
      541 gtttatcctt tttagacttg ttgtaatgtt ctcgtaattc tattccacat ttctttttta
      601 tctgtgcaat atataatgtc gaaactttta attcaaattt attccaaaca tattctttga
      661 tttgagcata tgttgctttg ctctccgcac ttgtcaaatt catctcatcc agctcaattt
      721 caacacttat gtgcttatcg acatcgagtt tggacaaaag tgctaccgtc tcgacgtgat
      781 gcgtttgagg aaatagatcc accggctgga ctttcttcaa ttcatatccc aattcttggt
      841 agagtttgat atcacgcgcc atggttgcga cattgcagga gatataggcg atgcgatcgg
      901 ctcctgtttg ggcgcttgct ttgataaagc tttctgtcaa gcccttgcgt ggaggatcaa
      961 ccaagataac ggttggttga atcccatctt taagccaatt cttcatagca ttttcagctg
     1021 tgtcacagac ataatgggcg tttgaaatat tgttcagctg agcatttttt ttactattct
     1081 caaccgcttc tggaatcagt tcaacaccgt agacttcttt gacatgcttg gcgactgata
     1141 aaccaatggt tccaatacca gaataagcat caataaccac gtcatctttt tttaactctg
     1201 caaagtcaat ggctgtttga tagagtttct ccgccatttc agtattgact tggtaaaagg
     1261 ctgggccagc gatttggaag tcatttccca acatctggtc cgtaatatag tcttgaccat
     1321 aaagagtgcg ccactcctta ccaaaaatcg cattggtatt ctggtcgttg atattttgca
     1381 tgacagacac aatctctggg aactgcttga taacttgttc aatcaattgg tcaacacgaa
     1441 aaacttttgg acgagttgtc accaaaacga ccatgatttg tcctgaatag tgaccacgac
     1501 gcaccacaag attccgaatc aatccagact gttccttttc gtcataaggt tttaaatcaa
     1561 aacgacggag caggtctcga agagctacta cgacttggtc aatgacagga tcctggataa
     1621 agaaatcttc aaggggcatg aggttgtgcg aattcttacg gaaaaatcct gtttccaaga
     1681 caccattcac tcgacgaacg ggcacctgcg ccttattgcg atacttgact ggatgttcca
     1741 taccaagcgt ttcagcaact tctacatctg caattccagc aatcttgtag agactgtcct
     1801 tgacttgctt ggttttaaac ttgagctgtt ctggataaga aaggtgtcct aaatccgcga
     1861 ttcctgaacg caggtaagcc aaatctagat cttgattacg gtgtggtgac tggacaaggt
     1921 atttttcaac ttttccaaag ccaatctttt tattgacctt gaggacacgc atgagaattt
     1981 tttcactcgg taaagcattc tctacaaaaa agaccaaacc atctaccttg gcaactcctg
     2041 ccccttcatg ggtcaaatca acaatttcaa cttctacaat atcatttttc tttaacattc
     2101 ttttctcttt ctattggccg acaaaaaaga cggcaacgtt acggttacca tccattatac
     2161 catgaaattt cttaagaacc aaaactcttg aagaagttga caagggcttg ccagagggag
     2221 cttaagaagt taccaccgtc ctctagcgcc ttatccgcat caaagttaag gttgatattt
     2281 ttaaaactgt cgccagcttg tgatacgatg ctttgtttaa ggtcatttag ggttttagtg
     2341 aaatctgcat tgctgaggat atcactcttt gagagattca aggcaaaatt gatgatgata
     2401 ttgatctggt ttcctgttat gacctgatca agtttgtaat tttttaaggt atcttcaaca
     2461 atcttgcgga tatcttcttc tgtcagattt cccttgcttt ctttagcttt ggcgagtcct
     2521 gacttgatat cagctagggc aacgtttaat ttattagcat catagcctga tttgtccttg
     2581 ttttcagcat tgatatctga caaagccttt agctcttctt gagccaaatc tttattggct
     2641 tgcggcacct tggctccatt agcttctagc gaatagtaga tcccagccaa agcactctca
     2701 cctgtaactg gaatgggtgc tgctacagtg attttggcgt gttccacacc caaagttacg
     2761 gctgcatttc ggtacatatc ctgagttacc ttagtgatgt tttcaggtgt ttcaatcttg
     2821 acctcaagtg gcgatttgtc acctagcttt tgaatcttgg ctgatgaata caactgtaag
     2881 ctagagtcat tggccacatt catgatttta gaataaacat caggtgtcat ggtcttaagt
     2941 tctttggtat ctgttgaggc attgtagccc agttttttaa gagtttgatt tttttggtct
     3001 tcagataggg aagaacctag gacatattca ggttggacat aggtttcatc gataactttt
     3061 tgaacatctg ttgctgcata gacgctattc atagctgtta ctgcccacaa gatcgcagcg
     3121 ctagtcagaa agagtttctt tctcataggg aatttcctcc tttacttctt tagagtaata
     3181 tatctatctt aaagaaaact tataacaaaa acacctggtc tagccagatg ttgaaaagag
     3241 agtgaaacat ttgatgatgt aaaggttaag tcgtacctgt ctagaataat aatagtttcc
     3301 tccatttaca tagagttcag caccgtgaaa aatggaaatg ggatgaatat aactataagt
     3361 ctttccagtc gtattaccaa gcaagggggc aacagtctca cgagagtact gtttggctag
     3421 agccaaggta ttttccttgc cattttgggc gataaaatcg atataggcag gtccaaaatt
     3481 ataggcttga acagctgtcc agatatctac acccttcttc tgcgccagat agagattgcc
     3541 tgtcagagtt tgaatgcctt gccgaatgct agaggcatta tcattgatgg tgttggtgga
     3601 accacttgca gactcactag actgcataac atcgccttct tttccttttg tttcagtata
     3661 aatcatagca agcacaagct cttcgtttgc tggggtgtct ttttcactca atatttctcg
     3721 caccatgggt tgataggtca tgacttgttt gacatcttga tgaacgcggt aagctttata
     3781 gccagcaaaa aggaagactg ctagtacaag cactcttcga attcgtttaa acattattta
     3841 ctttggatat cctcgatatt tttgattaag atagagtagg ttccattttc gttttggata
     3901 aactcaacag actcggcgtc ttgatagacg ttattgggaa cgatgagctc aattccattt
     3961 gataaggaga gtttttggtt ttcaaatttc tttaattggc gactggcatc aatttcatca
     4021 aattgaacag gttctggtac ggcttctttg acttggtcaa taaagctcaa acgagccgtc
     4081 agattgttgt caaaaaggtc attagccaat ttctcaggtg acaattcatt gctttcttct
     4141 aggttgttga aaatcgctga tttgaccttg gattgaaatt gaaaatcatc tgtgttaaaa
     4201 gattcagcaa ttctctgggc tgttttttcc agttccttga tagatttttt aggagaaatc
     4261 ttaggagcga cagcaagaag attatctgaa aaatagttca aaaaagtccc gttgtacttg
     4321 attcgttttt caatcaggtg atacttgcga ctctgaagat tgaccaccaa ggcctcgtca
     4381 gcacccgttc caaatccagg caggttattc tgagtcagct tgattggatt atcaacttct
     4441 cctccgaggt gggtcaaggt ctcccgcagg gcaattcgca agaaagcgaa atgttctaca
     4501 ccttctttag aaaattgaac aaaaatcaag tcattggtct tgagattttc agaaatgcta
     4561 aactcctctt tccagagatt agccagcgtt actgatgtct ccaacaaatc gtctgtaata
     4621 tgattgaaga agggattttc ttcttcgaaa atcccagtct tggcttcatc tgaatacaca
     4681 tgttcaattt ttttacgtag gtattcttcg atttttggag taatattgag aaacttatct
     4741 gctaagaaca gctcggtatc atccggactg aactggtgaa taatggcttt cttaatataa
     4801 atatccataa aagttttagt cctcgtataa tgggaaggca tctgtcaatt ctttgactgc
     4861 acttctcact tcttctaata cagcctcatt ttctgaattc ttaagggttt taatgatgag
     4921 ttcagccact ttgcgacttt cttcttcacc aaatccacgt gcagtaatag ctgctgctcc
     4981 gatacgaatc ccacttgtct tgaatggcga caaggtttcg taagggattg aatttttatt
     5041 tagggtaata ttgacttcat ccagcaagtt ttgagcaact tttccgtttt ctacaacctt
     5101 agtcacatca acaaggaaga gatggttttc agttccacct gaaataatac ggaaatcagg
     5161 gtcttgcaag aagacatctg ccatagcctt gctgttctta attacattgg cagcatattc
     5221 cttgaaggct ggatccaaaa cttctttgaa agaaactgct ttagccgcca caacatgctc
     5281 taaaggaccg ccctgaatac ctgggaaaat agctgaattg atttttttag caagttcttc
     5341 gtcattggtc aaaatcaaac caccacgagg tccacgaagg gttttgtggg tcgttgttgt
     5401 tgtgatatga gcgtatggaa ctgggcttgg atgaaggcca gccgcaacca aaccagcgat
     5461 atgggccatg tccaccatga gcttcgcacc gacagcatct gcgatttcac ggaattttga
     5521 aaaatcgata atttgagaat atgctgaagc accagctaca atcagttttg gttttacttc
     5581 ttgggcttgt ttcaagatag catcaaagtc taagagttcc gtttcaggat caacactata
     5641 agaaacaaag ttgtaggttt gaccagagaa gctaacagga gccccatgag tcaaatgacc
     5701 acctgatgcc aaatccattc ccataaccgt atcacctggc tcaatcaagg acatgtaagc
     5761 cgcacagtta gcttggcttc ctgaatgtgg ttggacattg gcaaatttag caccgaaaat
     5821 ttcttttgcg cgttcaatag caagagtctc tacaacgtct actacatcag ttccaccata
     5881 ataacggcgt cctgggtaac cctcggcata tttatttgtc aagatagacc cttgagctgc
     5941 cataacagcc ttggaaacta cgttttccga agcaattaac tcgatattat tttgttggcg
     6001 ttcttcttct ttggcaatag cattccagag atcagcatca tatgctttaa aatcatcttt
     6061 gtcaaaaatc ataggtcttc tcctttattg tgtgactagt ccattagttt gattttacaa
     6121 taagaaaatc aaactaaaag atgcgaataa accgtttctg cattttatca caagtatagc
     6181 caactttttc ataaaatgca tgagcaccca gacgatgatt ggcagaattt aagcggataa
     6241 acccataacc acatcttttg gcttcttgtt ccaacccttg tagtaaactt ttaccgatac
     6301 cttgaccttg cgcttgaggt gaaactgcta aagctaagat attaaatcct gctttggaat
     6361 agagtgattc gtaaacttca gcgtggacat atccaagtaa gacatgatta gctgcatcct
     6421 catagccaag taggaaatga tgggaatcct gagacagtct agctagttgg ctagccgttt
     6481 cctctggact aaaagtataa cccaaagcct cttggttgat gtcacatatc gctttcacat
     6541 ctgtttcttg caaatctctt agcatttcaa gcctcctcaa aagaaatctc tggcaaccga
     6601 gcaagaatat cttctcgttt aattgcgcct tggcgtaaga ttttcacctt gtctccagac
     6661 aaatccacaa tagttgaatc ctgtccagtt agaaaagcat cgtcttccag acccagaacc
     6721 tcttggtcaa aatccttcag aatttgttca aaggttacac cacttgcctg acctgagata
     6781 ttggcagacg gcccaatcaa gggacctgtc tctcgaatta aatccagtgt gatagggtga
     6841 ctgggcatcc gaaatccaat agttgcaagg tcagaattta cccaataggg aactcggtca
     6901 ttggcttcga gaataatggt caagggacct ggcaaaaagg tctctacaag tttttgtaga
     6961 taagctggct gattcttaga aaagtgcaag atatcctcta aagaggcaac attgagattg
     7021 agcgccttgt ctctaggacg acgtttgagc tggtaaacat ggtcaactgc tttttcgtct
     7081 aaggccttgg caaaaagacc ataaaccgtc tctgtaggca gaatgacagc tccaccattt
     7141 tccaactctt gtctaatcct gtccatcatc aaccacgacc atcctatctt gaccaaattg
     7201 gtccttgagt gttcgaactt ttttttcagg aagatgtttt ctaaaaagtt cgggaacact
     7261 ttgaccttgc ttgtatccaa tttcaaggta aatcttacca ccatctttga gatagtcttt
     7321 tgcatcttcc gcaattctac ggtaaatagc taggccatcc tcgtctgcaa agagagctag
     7381 atgaggctcc gaatacaaga cattcaagcc tacctctgac tcatcttcac gagagatata
     7441 gggtggattg gaaacaatta tatcatattt ttcagaaatt tctgtaaaac agtcagattt
     7501 tttaaaaaat atttgaagat tttgattttt agcattttcg ctagctaaat ctaaagcctc
     7561 ttgagaaaca tctgctgctg tcactgacca atctggtcta ttttttgcta gagcgagagc
     7621 aatagctcca ctacctgttc caatatccag aactgaaaga ttcgtctcaa gattttcagt
     7681 tagaataagc tccactaact cctctgtttc tggacgagga atcaaaaccc gttcatccac
     7741 ctttaaatgc attccataaa aatctgcctg tccaatgatg tactgagctg gcttgtgagc
     7801 tgctagttgc tggtaaatat cttctacaaa ttgtttttct tcctctgttg tcacctcctg
     7861 ctggagggca aaaataaagt ctgtaaaaga tagatttttc agactacgat agacaaaaga
     7921 gaggctttcc gcttcctctc cttgtcttat caactcttct tcaaaatttg aaaataattg
     7981 agctaatttc attatttgtt taattcttct agtttttgtg tttggtcata aagcaccaag
     8041 gcatccacaa cttcgtccaa tttaccagac aaaatcgtat ctagtttttg gagggtcaag
     8101 ccgatacggt ggtctgtgac acggttttgt gggaagttat aagttcggat ccgttctgaa
     8161 cggtcaccag taccgattgt cgacttacgc tcagcgtctt gttcatcctg agcaatctga
     8221 gcaaagtggt cagcgacgcg tgcacggata atcttcatag ccttctcgcg gttcttctgc
     8281 tgggtacgtt cttcctgcat ctcaaccttg atattggttg gcaagtgaac gatacgaacg
     8341 gcagtcgcaa ccttattgac gttctgtcca ccagcaccag aggcgtgata gatgtcgaca
     8401 cgaaggtctt ttggatcaat gtcgtattca acctcttcaa cttctggcat aacaagaact
     8461 gtcgctgtcg aagtatgaac acggccttgg ctttctgtca caggaacacg ttgcacacgg
     8521 tgggcacctg attcatactt aagcttagag tatacagact gacctgaaac catagcaacc
     8581 acttctttaa aaccaccgac accattcata gaggcttcca tgacttcaaa gcgccaacct
     8641 tgggcttccg catacttttg gtacatagtt agcaaatctc cagcgaaaag tgccgcttcg
     8701 tctccaccag ctgctccacg gatttcaagg atgatattct tgtcatcgtt tggatccttt
     8761 ggaaggagca aaattttcag tttttcttca tattcttctt tttcagcctt ggcatctttg
     8821 agttcttgct tggccatttc ttccaagtcc gcatctccgc ctgattcctt aatcatctct
     8881 tcggcatcga cgatattttg aaggacttgt ttatactcac ggtaggctat tacggtgtca
     8941 cgattggaag cttcttcttt tgaaagctcc ataaaacgct tggtgtctga aacgacatca
     9001 gggtcactca gcaattctcc tagttcttca taacggtctt ctacagcttg tagttgatca
     9061 tagatgttca ttttttctcc ttatttctca attgttaaat catagattgc tactacttca
     9121 ttctcggata tttccccagt ttctttaaat ccataactga gataacaaaa tcttgcctgt
     9181 tcattttctg gttcataaga caaccaaagt ttattgctta aacctgctgg cgctgttcga
     9241 acatagtcta gtactttatc cataattggt ttaaaatatc cttgattttg aaaattctta
     9301 tcaatcataa aacgaaatag taaataattt ccactactaa ttacgatctt tttatcataa
     9361 gctatcatca caaaacctat aattacatca ttatcataaa ctgccaatgg agctacaaaa
     9421 tctccatttt tagtgtagac gtatgcttca gctaaactaa ttgcgttggt tgcaatgaat
     9481 tgtttttgat attccttgac atccaaattt aaaacatcaa aataattttc cattgtaaca
     9541 tctcttagtt caattgtcat agttttgctc cttgttagag gttatcattg gcgcaaaata
     9601 atgtttacgg caaaccgaaa tataggtttc attaccacca atctggatct gttctccatc
     9661 gtaaacgggc agtccatcct gtgttcgcaa caccatggtc gcctttttct tgcaatactg
     9721 acagatggtc ttgatttcgt caatcttgtc tgctaaaagc aagagatatt tggaaccttc
     9781 gaacaattca ttgcgaaagt catttttcaa gccaaaagcc atgacgggta tgtctaactc
     9841 gtccacaaca cgagctaggt cgtaaacatg gtggcgtttg agaaactggg cttcatcgac
     9901 caaaacacag taaggttttt ctggtaggtc tcggatatag ccaaagatat ccgttgtttc
     9961 ctcaatcgta agggcagggc gtttcatgcc aattcgactc gacacatagc caacaccgtc
    10021 acgcgtatcc agagccgaag tcataatgac aacacctttt ccttgctcct cgtagttata
    10081 ggccactttg agaatctcaa tcgttttacc agagttcatg gtcccataac gataatacaa
    10141 ctgtgccatg tttcttgctt cacgtccatt tctaaatttt tgctacattc tagtatatca
    10201 taattttctt aagctttaaa cggcaaaatg tggtaaaatg gaagaaatca aaactagtgg
    10261 aggaagctat tatgccattt gtacgcatcg atttatttga aggacgcacg ctcgagcaaa
    10321 agaaagctct tgctaaggaa gtaacggaag cagttgtccg caacactgga gcccctcaat
    10381 ctgctgtcca tgtcatcatc aacgacatgc cagaaggaac ttacttccca caaggggaaa
    10441 tgcgtactaa ataagctagc ttaagcagaa ttgcttaggc tttttcaatc tccaagtagc
    10501 attcattgaa gaaatatcct aaatttgtta caatttgaaa agaaacttgg agaatttcca
    10561 agaaaatagc tattaattaa aggaaacatt atgattacac gtgaatttga taccatcgct
    10621 gctatctcta ctccactagg tgaaggggct attggtattg tccgcctgag cggaacagac
    10681 agttttgcta ttgcgcaaaa gatttttaaa ggaaaagact tgaacaaggt tgccagccac
    10741 actctcaact acggtcacat tattgatcct ctgactggta aagtcatgga cgaggtcatg
    10801 gtaggagcca tgaaatctcc aaaaaccttc actcgtgaag atattatcga gattaacacc
    10861 cacggtggga ttgcggtgac caatgagatt ctccagctag ctatccgtga aggagctcga
    10921 ttggctgaac ctggtgaatt taccaaacgt gccttcctaa acggtcgcgt agatttgaca
    10981 caggctgagg cagtgatgga catcatccgt gccaagactg acaaggccat gaacattgca
    11041 gttaagcaat tagacggctc cctttctgac ctcattaaca atacccgtca agaaatcctc
    11101 aatacacttg cccaagttga ggtcaatatc gactatcctg aatatgatga tgttgaggaa
    11161 gctactactg ctgttgtccg tgagaagact atggagtttg agcaattgct aaccaagctc
    11221 cttaggacag cccgtcgcgg caaaatcctt cgtgaaggaa tttcaacggc tatcattgga
    11281 cgtcccaacg ttgggaaatc aagccttctc aacaacctct tgcgtgagga caaggctatc
    11341 gtaacagata tcgctgggac aacacgagat gtcatcgaag agtacgtcaa catcaatggt
    11401 gtacctctca aattgattga tacagccggt attcgtgaaa cagatgacat agtggaacaa
    11461 atcggtgttg agcgttcgaa aaaagccctc aaggaagccg acttggttct actagtgcta
    11521 aatgccagtg aaccactgac tgcgcaagac agacaacttc ttgaaattag ccaagatacc
    11581 aatcgcatta ttctacttaa taaaaccgac ctgccagaaa cgattgaaac ttcgaaacta
    11641 cctgaagagg ttatccgtat ttcagtcctt aaaaaccaaa acatcgacaa gattgaagag
    11701 cgaatcaaca acctcttctt tgaaaatgct ggcttggtcg agcaagatgc tacctacttg
    11761 tcaaacgccc gtcacatttc cctgattgaa aaagcagttg aaagcctaca agccgttaat
    11821 caaggtcttg agctggggat gccagttgat ttgcttcaag ttgacttgac tcgtacttgg
    11881 gaaatcctcg gagaaatcac tggggatgct gctccagatg aacttattac ccaactcttt
    11941 agccaattct gtttaggaaa ataagaaaaa tccatgatcc ttcattcggt catggatttt
    12001 attgtcttta ttagtaatct ggtcttaaga cccctgttac agttgcctta gttgcttcgt
    12061 agtcgccatc tacgacaacc ttgataatgc gtttggcatc ttcttctggt gctggaacaa
    12121 gaggtagacg agtgggtcca gcttcaaatc ccatatagtt aagaactgcc ttaactggag
    12181 caggacttgg ataagagaag agagcattaa ccttaggaat gaatttacgc tgaattgctg
    12241 cggctttctt catatcgctt tctgcaatgg cagtaaacat ctcgtgcatt tcatccccat
    12301 ttgtatgaga ggcaacagaa ataaccccat ccgccccaag gttcatggca tggaaagcat
    12361 ctccatcctc acctgtataa atcaagaact cttcaggctt gtgctcaatc aaataagcca
    12421 tattagccaa gctagtacat tctttgacac cgataatatt tggatagtca gccaagcgaa
    12481 gcatggtttc tggagtcaat tcgacaacta cacgccctgg aatgttatag ataataattg
    12541 gtaggtcaga agcatctgca atagccttaa agtgctgata catcccttct tgagaaggtt
    12601 tgttgtagta aggaacaata gcaagcccag ctgcgaaacc accaaattcc gctacttctt
    12661 tgacaaactc aatagagtca cgcgtatcat tagtacctac acccgcaatc aaaggaacgc
    12721 gtccattgac aaccttttgt acagccgcaa acaactccaa ctcctcatcg tgggtcaaag
    12781 ttggactctc agcagtcgtt cctgcgagaa gaattccatc cgtatgatgg gccaataaat
    12841 gctcaatcaa ggctggaata gcatcaaagt taatggaacc atcctcatgg aagggggtaa
    12901 taaaggctgt aatgatttta cattctttta aatcttgata agacacgaaa acacctctct
    12961 atttcaaaga aggagttcat ctgaactcct aaacgatatg actattttaa ttcaaatttc
    13021 aattcggctg ttggacgaac caatccacgt tcatgaagag tttcagcaat ctgaactgag
    13081 ttccaagcag cacctttgag aaggttatct gaaacaaccc acatgtgaat tcctttttct
    13141 gcatccaagt ctttacggat acgaccaaca aaggtatcac gcgaaccaac tgcattgatg
    13201 gcttgaggat agatttgatg agctacatca tcttcaagaa cagcacctgg gaaggctgcg
    13261 atagctgctt ttacttcttc gattggagcc acttcttttg tttcgatata aacagactca
    13321 gagtgagctg acaagactgg aatacgcaca catgttgcag atactgcaat gctatcatct
    13381 tccataattt tcttagtttc cttggtcatc ttcatctctt cgtacgtgta atcattatca
    13441 gtgaaaacat caatttgtgg aagagcgtta aaggcgatag gataatgttt cttgtcacca
    13501 cctgaaggca aaatttccgc atgcaaatca catggtttca caccatcatt caagacttca
    13561 cgaagttcac gttgtgtctc aagaattgct cccataccag cacctgaaac ggcttgataa
    13621 gttgaaacaa tgatacggtc caagccccat ttttggcgaa ccggctcaag agccaccatc
    13681 atttggattg ttgaacaatt agggcaggca acgattccgt tgtgagcatc aagtgcatga
    13741 gcattgacct ctggaacaac caaaggaaca tctggatttt gacggaaata agatgtatta
    13801 tctactacta ccacgccagc ttttactgcg tatggtgcat acttagctga tgtagaacca
    13861 cctgctgaaa agagagcaat atcaactcct tcaaaagctg tttcagtcgt ttcttcaatc
    13921 gtaatatctt gatctttaaa tttcaatgac ttacctgctg aacgtgcaga agcaaggtaa
    13981 cggattttat cgattggaag tgttgattct tccaacattt ttatcatctg agcaccgaca
    14041 gcacctgtcg cgccgactac agcaactgta tatcccataa ataacctctt tcggaatttt
    14101 ctaaaaattt ctataataga agtattatac tactttttcc atgaattgca aagctttttc
    14161 atcatttttt ggaaaataaa aatccccaat cgctagacta gggattaaga ggcatcttca
    14221 tgtgatgagc aggttcacac aactcatcaa ggtccgctcc tgcgttatga cctccttatg
    14281 ctcaatagta gcccgaagac tacctatcga ctcatcgcat ctactattct actaaagaga
    14341 atgacttttg tcaacagacg aaactcttta tactcttcga aaatctcttc aaacttcgtc
    14401 agcgtcgcct tgccgtatgt atggttactg acttcgtcag tttcatctac aacctcaaaa
    14461 acatgttttg agctgacttc gtcagttcta tctacaacct caaagcagtg ctttgagcaa
    14521 cctgcggcta gtttcctagt ttactctttg attttcattg agtattagtt ttatttacac
    14581 aggtgcataa gaaatatatt ggaaaaattg ggggcagaca taacaaaaac ccttgtaaat
    14641 caagggcttt tctgtctatt taatgctaat tgccgggatt gaaccggcga cctcatcctt
    14701 accatggatg cgctctgcca actgagctaa atcagcttac ttaagaagta tactataatc
    14761 agaaaaactt gtcaagtttc cttagaaatt ttccatagga aaaagccagg taagaactac
    14821 ctagcttatc ttcttctatt tacttaaatc aattcgacga ccaattttac caataataat
    14881 cgctccaata atcaatgaag caaattcacc gattcctgtt gtaaaccaag taaggaagaa
    14941 tggtaattct gctacaatat ttaactctgc agcgatagta aacatggaaa ttgaaaagag
    15001 gattgaaaag aagaaatgat cttttcgaat caatccgtta aagaggtaat ccttgctata
    15061 ttttgcaaaa agccaaacac ctaaactgag gaatactaag gttgaaccac caccaacaaa
    15121 gacatctagc agtccgaagc taaagaaatt agcaatcata caaccgatgg taactccgat
    15181 gatgtactta ggattgtaaa aagccataaa gttcatcatt tctgaaatac gaaactgata
    15241 agcaccatag ctgatggcat ttaggggcgg tgtgacagtc aaaacgacgt agatagcagc
    15301 gacgattgca atatctgcaa catcacgaat agttaatttt ttcatctttt ctcctttggc
    15361 ggttatccgc gtgtaatatg cttggtgaaa gaagctaagc accaagggtt gattcattca
    15421 accttactag tatagcacaa tagcctgctt tatgctatac ttaaagcatg aaaaaaccta
    15481 ttcaaaaatt ttttaacaat gaaatcttag cctatctctt ttttggcctt gcgacaactc
    15541 tagtttcgat tctctcacga ctagtcattt atcaactaag tcatcaggaa ctccttgcta
    15601 cggccttggc aaatattatc ggtatcttat ttgcctttat cacaaatgat acgattgtat
    15661 ttaagcaaaa aaagaaaaat agacttatcc gtttagtgaa attttctctt gctcgccttt
    15721 ctacttttct gttagacttg tttttaactt ttctctttgt aacccaattt cctcacatca
    15781 tagggcaatt cgtaactgaa aacattgata agataaatgc tattgaaaca ataattgcac
    15841 aaatattcat tattatcatc aattatatct tgagcaaggt ctatattttt agaaaataat
    15901 gctccattta tgagcctttt aattgccttc tataatgatt taggatacaa tgaaacacga
    15961 aacattgaaa ggaaaacagt atgttaaaaa atctaaaatc gttcttgctt cgaggaaatg
    16021 ttattgacct tgctgtcggt gttgtcattg cctctgcttt tggtgctatc gttacttcac
    16081 ttgtaaacga cattatcact cctcttattt taaatcccgc tttgaaagct gctaaagtcg
    16141 aacgtatcgc tcaactttct tggcatggag tcggctatgg taacttttta agtgctatta
    16201 tcaattttat ctttgtgggt accgccctct tctttattat caagggcatt gaaaaagcac
    16261 agaaactgac tggcataaag aaagaaaaaa ctgccgaaaa aaaaccaacc gaattggaag
    16321 tccttcaaga aataaaagct ctccttgaga aaaaataatc gattaaaagg atctagcgca
    16381 aagctaaatc cttttttctt tactctttgg gtaacttgcc tgctttttca agcatttttt
    16441 tgataagata aggcatctta acattctccc gccctttttt ctcaatcagt tttttcacaa
    16501 attctggcat ttgtaaatct tcagattcag ctaaaatgtt tttcgtctcg tctgaaggaa
    16561 ctaactcatc aaaggtctct tcttctggga gaaattcctt aaactcttga ttttcattga
    16621 ctctaactgt attgaccaaa gcatcaatca aacgagaatc tgtatttggc attggtggac
    16681 gatggtagtt taccccaaat tcctggcata agtcataaca ttctacatca ttgtcaaaca
    16741 agacctcaat atgctcactg atgaaactaa tagatacaaa aatataatgg tctggatgtt
    16801 ctgtctgttc tctgagatac tccaaaacat ctggtttaat ccatggaata ccaatatcac
    16861 tctcactctg ccaagtgttg gtatattgtt ctgaactcaa gcccagtttt tcagcgacta
    16921 gcttgctatt ttcgaaaatt tggtctatat aaggatcacc aaagtccaag gcaaaaatgg
    16981 gcacactatg ggctgaaaag atgactttaa agctgtcttg ctttacttct tcttttaaaa
    17041 tcttagcaat ttcatctgcc caatagttta agagcgcttc ttcctgatac cagtccttaa
    17101 tgaccaaaaa ttgaatttgt ttgctttcta aaaatttttc atagcccatg acagagtaga
    17161 aagaataatg gggctccaaa atcaagcaaa tacactgttc aattccgtct gcttccattt
    17221 gaccgatcac atctggaata aagggactgg aaaacttatt agcaaagtag acactgtatt
    17281 cattccccag cctagcttct accaaggcaa cctcttgacg ggtaattttt tgcagaggcg
    17341 tgcctccaat tcgtacataa ttatcataga gagtctgaat ctcgtggtct tggggtctca
    17401 ccccacgacg aatatttgtg aaaaaatcag ctacaccttc aaaggtaatc tcttctggtg
    17461 aaccgaaggt catcattaaa attgcttttt tcatgactgc ttccttgtga tgtttttatc
    17521 aagtttattt tatcattaat tcatcgataa gtaaacgcta acatagggac attctcaatc
    17581 ttctgtcttt tgtttttctc ttctttctat gatacaatgg aaaaaataaa ttcaaaagga
    17641 gtttttttat gacttatcca aatctcttgg accgcttctt aacctacgtt aaggtcaaca
    17701 cgcgctctga tgaacactct actactactc caagtacaca gagtcaggtt gacttcgcaa
    17761 caaatgtcct aattcctgaa atgaaacgtg ttggactgca aaatgtttac tatctaccga
    17821 atggttttgc tattggaacc ttgccagcca acgatccgtc tttaacacgt aagattggtt
    17881 ttatatcgca catggatact gctgatttta atgctgaagg agtcaatcca caggtaattg
    17941 aaaactacga tggtggtgtg attgaactag ggaattctgg tttcaaactc gatccagctg
    18001 acttcaagag tcttgaaaaa tatccaggac aaacgctcat cacaacagat ggaacaagct
    18061 tgctaggtgc tgatgacaag tcaggaattg ctgaaattat gacaaccatt gaatatctaa
    18121 ctgctcatcc tgaaattaag cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa
    18181 tcggtgttgg tgccaataaa tttgatgcag aagattttga tgtggatttt gcctacactg
    18241 ttgatggtgg tccactaggt gaacttcagt acgagacttt ctcagccgct ggtgctgaat
    18301 tgcatttcca aggccgtaat gtccaccctg gtactgccaa agggcagatg gtcaatgccc
    18361 ttcagctagc aattgatttt cataatcaac ttccagaaaa tgaccgacct gagttaactg
    18421 aaggttacca aggtttttac catctaatgg atgtgacagg tagtgttgag gaggtgcgtg
    18481 caagctacat cattcgtgat tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc
    18541 aatctatcgc tgataagatg aatgaagaac ttgggagcga ccgtgtcact ctcaacttga
    18601 cagaccagta ctacaatatg aaagaagtca ttgaaaaaga tatgactcca attaccattg
    18661 ctaaagccgt tatggaagat ctaggtatca cgcctattat cgaaccaatc cggggtggaa
    18721 cagacggctc taagatttcc tttatgggaa tcccaactcc gaatatcttt gcaggtggcg
    18781 aaaatatgca cggacgtttt gaatacgtta gccttcagac tatggaacgt gcagttgata
    18841 ccatcattgg catcgtagct tataaaggct aaaaagacga ggtagctcag ctacttcgcc
    18901 tttcttttta ttctactggt ttttcttgat ttccagtagt tgtagaagat tctgttgttt
    18961 cattttctga agttgattca gcaggtttag aatctcttgt attgcttggt ttgttttcgt
    19021 cgctagcagt ttcaatgtta gattctgcag ttgcgtttgg ttggttctca gcactggtgt
    19081 tatcactatt tgcttcagca tttcttgctg gacttgtttc ttcacttgcg ctagcttttg
    19141 actggatttg atgattcaaa actagaatag cttttgtcga ttcaagtaaa gctgttttgt
    19201 ctttactctt agcagaaagt tgatctaata atgcatccac cttatcaaag tccgcatcag
    19261 atccattatt actttctaaa taagagtgaa gcgacatgag aatatcgtag agtttttgat
    19321 agagtacaag tgtctgagaa tcttgctcag cattttcctt ttcttgttga agggcgctag
    19381 cgatacgagt caaaacatct tttacctgac tgtttacttc atccaagtct gcatcagcct
    19441 tgtttgtggc agcttttaga ttttctactt cttctgccaa ggattgtctg attccttctt
    19501 catggatttg ttccaagagt tgatttgcat tgttcaaaag actttctact tcttcctttc
    19561 tatctgtcgc agattattgg ttgctatcta ccatgtactc ctaaaacagg agagttataa
    19621 tccaagatta caaggcctta cagaaataag aaatccagat aagacaatgt tcgtccaaga
    19681 cgctattcgc ttcgcacagc agcacagatt caatatactt taattttaaa gtttaggtgt
    19741 caagacctct ttttagtgtg cccaaaattt agagaagtaa tcaatcaact aacttttatt
    19801 tttttcaaac tttcagtaaa ctgacctaaa gctaactcaa tctgtctttg tagatgcttc
    19861 tgctatcagc tagaagttga tctacttttg ccaagactgc cttctcatca aaagttccag
    19921 gttgatagtt ggattgcagg gatggaatct tgtttttcaa agccgcttca tatcccttag
    19981 tttgaacctt gatgtagtga ttgtggtcgc catgaggaat cacaaaacct tctgaatctt
    20041 cacttataat tcgattggca tcaaaaacca tgaccatctt cttcctcatg gtggacatgt
    20101 agtgacggat tacttaatac agaactagaa gaacttccta cctcttccgt gttagagtgt
    20161 gatgggggat tgttaagaga tgacttagga atatagtgat agtgttcccc atgtcttact
    20221 atataagcat cacctatatc tctgacaata tcattagggt taaagacata tgtggctgct
    20281 aattcacctg ccgacaagtc actctcagga atgaaatgat agtgaccacc atgtggtact
    20341 atagtaggtt gaaatagaat atgagcaaat tgataagggg attttaaagt aatttctaac
    20401 aatgatttag aaactatgat gtgctattct aaattcaact cactatatat aaccatcatc
    20461 ggtagtataa cgtccctgta attttgctac agatacttct gcactagctc ctttatcgtc
    20521 tttaccatgt tcttgttttt ggcgattgat ttcatctttt gttcgtacat tttctgcatg
    20581 agcttgatct ttaaggtaaa cataatactt tccatctacc ttaataatat atcctccctt
    20641 aacctaactg acgatatctt gatctttcgg ctgatagttg ggggctttca ttagtagctc
    20701 ttcactaaag agcgcatcaa aaggaacttt accattatag tagtgataat gatcgccatg
    20761 agaagttaca taaccttgat ctgtaatctt aataacaatt tgttttgctt gaattccttc
    20821 tttttgacta acctagtctg gagtcaaatt ttcagtcttc ttagtgtctt tattactgtt
    20881 tacatatgaa acacgatttt tatctgtatt ggcctgttag ctatgttggt tcagagcata
    20941 aacacacaga cttaaggaaa ggataacaac agatccagct gctatatatt tctttttaaa
    21001 tttcataatt acctcatt
//
LOCUS       DBJKQU010000034        21007 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.034, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000034 DBJKQU010000000
VERSION     DBJKQU010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.034"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            1..608
                     /locus_tag="ACSUUC_001420"
                     /pseudo
     CDS             1..608
                     /locus_tag="ACSUUC_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(601..774)
                     /locus_tag="ACSUUC_001421"
     CDS             complement(601..774)
                     /locus_tag="ACSUUC_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HHQ8054614.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(933..2540)
                     /locus_tag="ACSUUC_001422"
     CDS             complement(933..2540)
                     /locus_tag="ACSUUC_001422"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_function: GO:0004574 - oligo-1,6-glucosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009311 - oligosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HHQ8054615.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENSNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPMQEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2693..4177
                     /locus_tag="ACSUUC_001423"
     CDS             2693..4177
                     /locus_tag="ACSUUC_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HHQ8054616.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            4272..4754
                     /locus_tag="ACSUUC_001424"
     CDS             4272..4754
                     /locus_tag="ACSUUC_001424"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HHQ8054617.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(5050..7155)
                     /locus_tag="ACSUUC_001425"
     CDS             complement(5050..7155)
                     /locus_tag="ACSUUC_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHQ8054618.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(7764..8744)
                     /gene="mraY"
                     /locus_tag="ACSUUC_001426"
     CDS             complement(7764..8744)
                     /gene="mraY"
                     /locus_tag="ACSUUC_001426"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HHQ8054619.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(8746..10998)
                     /gene="pbp2X"
                     /locus_tag="ACSUUC_001427"
                     /gene_synonym="pbpX"
     CDS             complement(8746..10998)
                     /gene="pbp2X"
                     /locus_tag="ACSUUC_001427"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HHQ8054620.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(11002..11319)
                     /gene="ftsL"
                     /locus_tag="ACSUUC_001428"
     CDS             complement(11002..11319)
                     /gene="ftsL"
                     /locus_tag="ACSUUC_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HHQ8054621.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(11331..12281)
                     /gene="rsmH"
                     /locus_tag="ACSUUC_001429"
     CDS             complement(11331..12281)
                     /gene="rsmH"
                     /locus_tag="ACSUUC_001429"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HHQ8054622.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            12447..12641
                     /locus_tag="ACSUUC_001430"
     CDS             12447..12641
                     /locus_tag="ACSUUC_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHQ8054623.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            12657..13199
                     /locus_tag="ACSUUC_001431"
     CDS             12657..13199
                     /locus_tag="ACSUUC_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HHQ8054624.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            13210..13452
                     /locus_tag="ACSUUC_001432"
     CDS             13210..13452
                     /locus_tag="ACSUUC_001432"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054625.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            13463..13798
                     /locus_tag="ACSUUC_001433"
     CDS             13463..13798
                     /locus_tag="ACSUUC_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054626.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(13908..14909)
                     /locus_tag="ACSUUC_001434"
     CDS             complement(13908..14909)
                     /locus_tag="ACSUUC_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHQ8054627.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(14969..16870)
                     /locus_tag="ACSUUC_001435"
     CDS             complement(14969..16870)
                     /locus_tag="ACSUUC_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HHQ8054628.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDMLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(16892..17185)
                     /locus_tag="ACSUUC_001436"
     CDS             complement(16892..17185)
                     /locus_tag="ACSUUC_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HHQ8054629.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQTEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(17185..18003)
                     /locus_tag="ACSUUC_001437"
     CDS             complement(17185..18003)
                     /locus_tag="ACSUUC_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHQ8054630.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVVIGIIGSWLKIIA"
     gene            complement(17990..18769)
                     /locus_tag="ACSUUC_001438"
     CDS             complement(17990..18769)
                     /locus_tag="ACSUUC_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HHQ8054631.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGLGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            complement(18784..19275)
                     /locus_tag="ACSUUC_001439"
     CDS             complement(18784..19275)
                     /locus_tag="ACSUUC_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHQ8054632.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLACNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(19286..20476)
                     /locus_tag="ACSUUC_001440"
     CDS             complement(19286..20476)
                     /locus_tag="ACSUUC_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HHQ8054633.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(20488..20916)
                     /locus_tag="ACSUUC_001441"
     CDS             complement(20488..20916)
                     /locus_tag="ACSUUC_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHQ8054634.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
BASE COUNT         6155 a         4746 c         3765 g         6341 t
ORIGIN      
        1 ttctgaattt ggctgtcatc caactaccat ccactatgcg ctcaaagcta tgggctacac
       61 tcgaaaaaag aaccacacct actatgaaca agacccagaa aaagtagcct tatttcttaa
      121 gaattttaat agtttaaagc acctagcacc tgtttagatt gatgaaacag gaatcgatac
      181 ttatttttat cgagaatatg gtcgctcatt aaaaagtcag ttaataagag gcaaagtatc
      241 tggaagaaga tatcagagga tttctttggt tgcaggtcta acaaatgaat ggtgagttaa
      301 tcgctccaat gacttacgaa gagacgatga cgagcgactt ttttgaagct tggtttcaga
      361 agtttctctt accaacatta accacaccat cggttattat tatggataat gcaagattcc
      421 atagaatggg gaagctagaa ctcttgtgtg aagagtttag gcgtaaactt ttacctcttc
      481 ctccctactc acctgagtac aatcctattg agaaaacatg ggctcatatc aaaaagcacc
      541 tcaaaaaggt attaccaagt tgcaatacct tttacgaggc tcttttgtcc tgctcttgtt
      601 tcaattgact atattatcag cgtaatagtc taatagatag ttaaatgtag ttggatttcc
      661 actaaaggtt gatgagtaag tttttgtatc tgagcctgat tggccgcaag cagctaaaag
      721 caaagcagat gcaaaagtca ggcctgcact aagaacacgc ttctttatgt tcatcttctt
      781 tctccttaat agtgggaatt tgtaaagtta attgaatttc gaaaatgaaa gtttataaac
      841 cttggttata aaaaacaaag gatttctgct ttttatacag tcctcccttg tttttatatg
      901 atttcaattt taaatttttc tgcaaaaaat atttatagta attccacaca gaaagcatcc
      961 catggaacta agatttgttt ttcaaaaact tcttgagcta gggtgttttc aatcaagaca
     1021 gatttgactt ttccttctac tgtcaagtct tgctcttcat tggacaagtt agccacaact
     1081 aggaagcgac ggtcgccatc cttacgtata taagcaaaga ccttatcagc cgtatcaagc
     1141 aattcaaagt cagctcgaat tagccagcta ttctccttgc gaatttggac cagtttctga
     1201 taggtataga aaatagaatc tggatttgcc agcgcttctt ggacgttgat catctcgtaa
     1261 tttggattaa ctgccaacca aggttgacct gttgagaaac cagcgttttt gctctcgtcc
     1321 cattgcatag gggtacgggc attgtcacgt ccaataacac ggatactgtc catgatttct
     1381 tgcatcggaa cacctttttc aagagcctca cgcgcatagt tgagagattc aatatcttct
     1441 acttgatcta gtgtttcaaa cggatagttg gtcatcccaa tctcctcacc ttggtagata
     1501 taaggagttc ctctcatgag atgaagtaag attgcaaagg ctttggcaga tttttcgcgg
     1561 tattcttggt catttcccca gattgagaca atacgaggga ggtcatggtt gttccagaag
     1621 agggaattcc agccgtcctc aactcctaac tctgtctgcc atttgttgaa gatttctttt
     1681 aacttagcga tattcagttc tttttgatag tgccatttag gctgaccttc ctgatactga
     1741 agaccgatat gttcaaactg gaagaccata gacaattctt gcccctttgg atcagagtag
     1801 agcttggcaa tctctggcgt tgctccccaa gtctccccta ctgtcaagag atccttatct
     1861 ccaaaggtcg cctgattcat ttccttgaga tagggatgga gcataggacc attattgact
     1921 accttctcgt caggaatttt gccaatcatg tcaataacat ccatacggaa accaccaata
     1981 cctttatcaa tccagaagtt catcatctca taaattttct ggcgaagttt ttcattttcc
     2041 cagttgagat ccggctgttt cttgctgaaa aagtggagat agtattgacc agatttttca
     2101 tcgtattccc aagcagatcc actaaaaata gaatctaaat cgttaggctc atcccgccag
     2161 atatagtaat ctcgctcagg gctattagaa ttttcacagg cctctacaaa ccaggcatgc
     2221 tcatccgagg tatgattgac caccaagtcc atgatgatac gaatgtcacg cttcttagct
     2281 tccgcaatca gttgatccat atcctccatg gttccaaaaa tcgttgcaat cgcttgataa
     2341 tcagcaatat cgtagccatt atcatccata gggctgtcat aaacgggaga aagccaaatc
     2401 gctgtgattc ctaacttagc tagatagtcc aacttactgg taatacctgg caaatcacca
     2461 actccatctc cattactatc cataaaactc tttggataga cttgatagac tacggcatta
     2521 tgccaccatt tttcttgcat ctgtttacct cattattttc ataatctata gtatatgata
     2581 acacttttta aaattttgtg caagcgtttg cttaatcttt ttaatttctt ttttagctcc
     2641 gtagtttcct aacttccaat tttttattat aatagaggtc agaggtaaaa aaatgaaaaa
     2701 acaagctttt agttctgaac aatatttgaa tttacaacgc gaccatattt tggaacgcat
     2761 taaccaattt gacggcaagc tctacttaga gtttggcggt aaaatgttag aagatttcca
     2821 cgctgctcgt gtccttcctg gttatgaacc tgacaacaaa atcaagctct tgcaagaatt
     2881 gaaagagcag gttgaggttg tgattgccat taatgctagc aacattgaac attccaaagc
     2941 acgtggcgac ttaggcattt cttatgacca agaagttctt cgtttgattg acaaattcaa
     3001 tgaattaggg atttttgttg gttccgttgt cattacacaa tacgctggcc aacccgctgc
     3061 agatgccttc cgcaatcaac ttgagaaaaa cggaattgat tcttatcttc attatccaat
     3121 caaaggatat ccgacggata tggatcacat catttcccca gaaggcatgg gcaaaaacga
     3181 ctacatcaaa accagtcgca acttgattgt cgtaaccgct cctggacccg gttctggaaa
     3241 attggcaacg tgtatgtcca atatgtacca cgaccaaatc aatggcatca aatctggcta
     3301 cgctaaattt gaaaccttcc ctgtttggaa tcttcccctt catcatccag ttaacttggc
     3361 ttatgaagct gccacagctg accttgatga tgtcaacatg attgacccct tccatcttca
     3421 aacctatgga gaaaccactg tcaactacaa ccgtgatata gaaatcttcc cagtgctcaa
     3481 gcgcatgttg gaacgtattc tcggaaaatc accatacgct tcaccgacag atatgggtgt
     3541 caacatggtt ggtttcgcta ttacagatga cgaggctgct gtcgaagctt ctaaacaaga
     3601 aatcatccgc cgttactatc aaacagttct tgacttcaaa gctgaaaaag ttggcgaagc
     3661 tgccgtcaag aaaattgagt tactcatgaa cgacctcggt atcacacctg cagaccgtaa
     3721 ggttgctgtc gttgcgcgcc aaaaagcaga agaaactggt ggaccagccc tagcctttga
     3781 attgccaaat ggggaaatca tcactggtaa gaactcagaa ctctttggcc ctacagccgc
     3841 tgccttgatc aatgccatca aaaaatcagc tgacatcgct aaagaagtaa aactaatcga
     3901 gcctgaagtt gttaagccaa tccaaggtct taaaatcgat catctcggta gccgcaatcc
     3961 acgccttcat tcaaatgaaa tcctgattgc acttgctatc acagctacag aaaatcctga
     4021 tgctgcccgc gctatggaag aactcggcaa cctcaaagga agcgaagccc actcaaccat
     4081 catcttgact gatgaagaca agaatgtcct tcgtaaactg ggtatcaacg taacctttga
     4141 cccatactac caatacgacc gcttatatcg taagtaaaga tttcaacctc tctagcctcg
     4201 gagaggtttt ctctctgtct caggaacaac ctttatgata taatgagaga agaaaactga
     4261 aaggatttac catgtcaaaa gaagttattg tcgaaagttt tgaacttgac cacaccattg
     4321 tcaaagcacc ctatgttcgc ttgattgggg aagaaacagg accaaaagga gacatcatct
     4381 ccaattatga tattcgcttg gtgcaaccaa acgaagactc tatccctact gccggccttc
     4441 acactatcga gcacctctta gccaaactca tccgtacccg cattgacggc atgattgact
     4501 gttcaccatt tggttgccgc acaggcttcc acatgattat gtggggacgt cacaccagtg
     4561 ctaaaatcgc agctgttatc aaggattcgc tcaaggaaat cgctgaaact actacttggg
     4621 aagatgtccc agggacaacc atcgaatctt gcggaaacta caaggaccac agcctcttct
     4681 ctgctaaaga atgggcaaaa ctcatcttgg aacaagggat ttcagatgat gcctttgaac
     4741 gtcatgtgat ttaaaatcga gtaggggata atctctagcc cctctcacac caccgtacgt
     4801 accgttcggc atacggcggt tcaactaact tttaacgcat gtcgttcaag gtaataatcc
     4861 aaacacgaaa ccagtccacg tttttcaagg actggttttg atatagcacg tttaagtacc
     4921 gacttctgag ctactatagt atattgaaac tggaataata cacttctact atacgacatg
     4981 cctgtcgtac ctaaaaagga accagttttt ttcagctggc tccttctttt ttatcctcaa
     5041 aattctatct taggctttct cacgaataac caaaacgcca tcttccatat ctgcttccag
     5101 atgtttagca tctaaatgat ccaagtggaa gtctgtcacc ttatcacgaa tttcttgttc
     5161 aaccacgcga cggagaggac gaacccccat gacttcgtcg taaccttctt ctgtgatata
     5221 atctttagcc gcttgactaa ctaccaagtc aatgtctttc ttagccaagg tttggttaac
     5281 ttcagccaac atcaaatcta caatcttaga aaggtcttcc ttagtcaagt gtgagaactc
     5341 gatgactgca ttaaagcggt tgaggaattc tggacggaag aagggtttca aacggtccat
     5401 caattctggt ttatccgcat cttctgtcaa gttggcttca tagccaaatc cagcatttga
     5461 ggtcgcaata acgacagtat tcttgaagtt tactgtattt ccttgaccat ctgtcaaacg
     5521 accatcatct agaacttgga ggagaagggt aataacttga ggatcagcct tttcaatttc
     5581 atccaagaga atgatagagt atggattgcg acgaacacgt tctgttaagg tattgctatt
     5641 gtcatcataa cccacatagc ctgctgttgt accaattagc ttagaaacag ctgtgcggtc
     5701 actgtattca gacatatcca aacggataat cgcatcctgg gttccaaaca tatcgagtgc
     5761 caattgctta gcaagctccg tcttaccaac cccagtagac cctacaaaga ggaagctgcc
     5821 gattgggcga tttccttcat caaaaccagc acggttacga cggatagcac gagctacaac
     5881 ttctacggcc ttatcttgac caatcacctt ttcttgcaag cgatgagcca tatctttcaa
     5941 acgttcgata tctgaagctc ccatttgcga tactgggata cctgtcattc gttccacaga
     6001 ttcagccaca tcgttgacac ttgcagtcac tttcatatct tctgtgtggt tttcgatttt
     6061 cctttccaat tctgcaatgc gtgttttata gtttagagct gcttcaaaat cttctgcttc
     6121 aactgctttt tcttgcttgt ctttttccgt ttcgatttct cgttcaacag catgcacatc
     6181 tgttactgga tgttgagccg ccaagtgagc agccgttaca tcgacaaggt caatagcctt
     6241 atctggcaag ctacgttgag gaatgtattg aacagaataa tccaccgctg ctttcaagac
     6301 ttcgtctggc aagatgacat tgtggtgttg ttgatagagg tcacgaatgc cttgaagaat
     6361 tttaaaagta ttctctgctg aaggagcatt gaccttcact tcgttgaaac gacgagcaag
     6421 agcagcattc ttcaagatgg tgttacggta ttcgtcttga gttgttgccc caatcactgt
     6481 caattctcca cgagagagag ctggcttgag aatatccgca agtcctttag aaccactgtc
     6541 tccaccagtg ctaccagcac caagaatttg gtgaatttca tcaaagaaga ggataatatt
     6601 ccctgcttct ttcacttcat tgactaagtt ttggacattt tcttcaaagc taccacggta
     6661 ttgagtacca gcctcaagac ctgagatatc aatagaaata atttccttgt tcttgatagc
     6721 agcaggaaca tctccgttca caatggcttg cgctagacct tcgacaactg ctgtcttacc
     6781 aacacctgca tctccgacca aaacaggatt gttcttggtg cggcgtgaga ggatttcaga
     6841 tgtttcttga atttccttgt ttcgtccgat aacaggatcc aacttgccct cacgcgcttc
     6901 tgctgttaag tttcgaccta gttttgcaag gacaccgtct tgtttcatac ctgatgcctg
     6961 ttgtggcatt tgcacatcag tttctgcatt tcctggtaat tgaccagtcg cacgatagtg
     7021 agcaaattcc tcaggtgtga cttcgcgtcc attaattaag taacggcgat tttcagaact
     7081 atatcctcgc ataccaccca tcaattggtt aaataaatca tccatgttat taaaattatt
     7141 aaagttgtta ttcatattct ttacctcttt ttgtttactt agttatgatt actgatattg
     7201 actatctttg accattgttt taaaaaattt agactagcta gatcgctacc ctacgtacta
     7261 tttctggttt ttctttttca agcaggagta gactatcttt acctctgaag attgctagat
     7321 gaaacataga ctcacctctt tctattttac tttaaataag tgttctagta aggctttcat
     7381 ttaccttacg ttcataatat actacattgg tcagaaaagg tcaagagttt tgactttaac
     7441 tgaccaatat ttttttacac tcttcgaaaa cctcttcaaa ccacatcagc ttcgccttgt
     7501 ctacaacctc aaaacagtgt tttgagctga cttcgtcagt tctatcaacc atctcaaaac
     7561 tgtatagtaa aatgaaataa gaacaggata aatcgttcag gacagtcaaa tcgatttcta
     7621 aaaatgtttt agaagtagag gtgtactatt ctagtttcaa tctactatat tttgagcagc
     7681 ctaaagttag ctttctagtt tgttctttga ttttcattgt gtatttaaac acaaaaacac
     7741 cctgaaacat cagggtgcca ttcttacatc aaatacaaaa ttgcaagggt caggagactt
     7801 gctagaagcc caactcccca aaagaagaag tcaaccttcc actcgctcca aggatttcct
     7861 ttaccagaca atcccccaag ctcaaaatgg tgatgtacag gcgtcatacg gaaaatacgt
     7921 ttaccacctg tcagtttgaa ataactgact tgcatcataa cagaagttgt ttcaaaaaca
     7981 tatacaattc cgataatcaa gagagtccat tcttggtgga gagccataga gatagctgcc
     8041 agcatcccac ctagggccaa acttcccaca tcacccataa agaccttagc aggcttatgg
     8101 ttaaagatga aaaaactgag caaaccacca atcatggcaa gaatcactag aagaatatcc
     8161 atctgacctt gcacataggc aataactcca taggcagaca aactaatcac aacggaaata
     8221 ctagctaaac cgtcaacacc gtctgtcaag tttactgcgt ttgaaaaacc gactagccag
     8281 aaaagagcga agacaatata gaaaatccct agatgcactt gataaccaaa gacagaaagc
     8341 atatcgccac cgcgctcata gaaaagatag aagataactc cacctagaag ctgaagagct
     8401 aatttttgct taggattaag cccctcattg attttacgaa agaccttgag aaagtcatct
     8461 aaaaatccga ccaagccata caagaccaag atgaacaaaa tcattcccat attattgctg
     8521 aattggctac taaatagggc gaaaaagaaa gcaaccaaaa cagaagtaat caagaaaacc
     8581 aaacctccca ttgtaggagt cccagctttt gcctgatgct gtttgacatc ctcatgcatc
     8641 tgctggcctg taatttgcgc ctttctataa aattggataa aggccggaat tcctactaaa
     8701 gttagtaaaa atgtcacaat tccagcactg atggaaataa acatattagt ctcctaaagt
     8761 taatgtaatt tttttaatgt ccttgatagc tgtgttagca cgaacatctt gcttctgcac
     8821 agtagagccc gaaccttgaa attcaagttc tatattgagc cacttagcaa gggtctcagc
     8881 agtctccttt gtccaaccat acatatctgg aacttcctct actttatcag ataagataag
     8941 gacttgctga ttcggggcaa gattcttccc ttcttcagca gaactgtttt taatcttcgt
     9001 tcctgttccc acaacgatgg gttgtacaag attgcgacgc aattcttctg ctaaatcacc
     9061 aggtgaaata tccttgacac taggcatagg ataaggactt tgttgactta cttgctccaa
     9121 agctttagct gttgtttgaa gattgagaga gtctttcata gctgaagccc gctccaagat
     9181 aggattggca aattctccca actgaatacc tgaataatgt tcaggttgtt ggaccgtcac
     9241 atacaagata aaatcaggat tttcagccgg actcatcgat acagccgaga aaatatagtc
     9301 ggttaacccg actagataac caccattttt ctcgtcagca atctgagccg taccagactt
     9361 gagggctaca ttttgcccag gaacagttac agttggcttg cctgtgctgt ggttatacat
     9421 ggttccataa accggatccg tccctaccaa aaccatgtta gtccgagtta gactagctgc
     9481 atctttagaa acaggatttc ccacaatttc tttttgagat ttccgagcag tttgatcatt
     9541 tggatcataa acggcactaa taaatttagg ctccagcatg acaccgtcat tagcaatagc
     9601 tgtaaaggca cgaatcattt gcgtctgggt cactgaaatc ccttgtccaa atgagctttg
     9661 cgcaatgttg acaatattat ccgcaggaag ctgaccagca tactcatccg tcaaaccgaa
     9721 acgggtcgga actccaaact taaaacgatt aagataatca agccaggtag catctcccat
     9781 cttttgctca aggagggtca tcccaacgtt acttgagtgt gcaaaacctt gagaaaaagt
     9841 catcattctg ccaccagtca atccttcatt aacgtcccaa tctcgaatcg tggcatctgc
     9901 aatttttaac tcactactat taaagacttc tcctcctgga aaggtattat tatcaatagc
     9961 agcagccaac atcatcactt tcatagtgga acctggctca tagttacttt ggtaaaggat
    10021 atcacgccaa acaaagtcct ctgtaatgcc ttcttttgta tctgcatcaa aggtcggtcg
    10081 ttgcgttgtt gccagaattt cccctgtttt agcactgacc aaagtcgctg tcatgtactt
    10141 tccttttacc ttctcttgaa aagaatccat ctgggtttcc ataaaggact ggagggggct
    10201 ggaaatggtt gtataaacat ccttaccgtc catcgttcgt tgggaaactt gttctgttcc
    10261 gggtacaata ttacccagac gatccttttc ataggtaata atgccgtctg tccctgcaag
    10321 aatactgttc aaggaactct ccattccaga ggttcccagc aagctcttgc ttccatcttc
    10381 attttcatgg agctgagcta ggccgataaa actagaagca aattgtccgt ttgggtaact
    10441 acgattggga ctggttgtaa aatcaatccc cttgacctct gcagcttcca attctttttt
    10501 gatagacatc atattggcat aggtaatccc atttcccttt gctccaaagg aaacttgctt
    10561 gagattaggt tgcgagagtt gctctcttac ataggattct tccatgtcca gatacttatg
    10621 aaagacctct gcaaccttgt taaattgtgt tttttctacg taaagaatct tacccgttgc
    10681 tgacttatag ttctcatcaa tgaccgcata gacattatag gaggttgcat cctcagcaat
    10741 cgggactcca tttcggtcat aaatagtccc acgtttggca ggaactgtac gggtggtttg
    10801 atgaaccttc ttagcttcct tcgctaaatc tgttccaaag cgagtgcctg tcccaataat
    10861 gaccgcaaaa ttgactaaaa aaatggcaaa aacaaagaca gataataaac tcagactttt
    10921 tccaactctg cgtctgtttt cagccggcga tttccgattt ttggtcgcat aacggattac
    10981 tctttttgtc cacttcatat cttactccgc tattctaata ttttcattgt ttaattgcaa
    11041 atcgtgtgaa ttggcaattt ctttcaaacg ttctgcacgt aatagttcat tgacctcttg
    11101 cttggcatcg tccaattcgg tcttcttttc ctctatctgc gcattgattt ttgtcaaatc
    11161 attctgcact tgcaagagct tggtctgcat aaaaataata ctaatggcta caataagagt
    11221 ggttacagca atggaaaagt aaaaagcttt ttccacacgc gaaaaccgtt taagttgcat
    11281 ctgtagtatt tgacctgttt tttccatttt ttctgccatc tttttccctc ttacttgtga
    11341 atttttctgg ccacgcgcaa cttggctgag tgcgagcggt tattggcttc taactcttcc
    11401 gcacttggca agattggctt acgggacacc aattccatct tgggcttgag atcatctggg
    11461 atgaaaggca agccttttgg aacttcaact gttgaagctt ccttgaacaa ttgcttggtc
    11521 aagcggtctt ctaaggaatg aaaggtaatc actgaaattc taccatccag agccaacata
    11581 tccatagcct gctggatgga ctcatctgcc gctcccagtt catcattgac ttcaattcga
    11641 atagcctgga aaatctgctt agcaggatga cccttcttct tgagttcctt ggcaggtttg
    11701 accaacttga taatctctgc taactcagtc gttgtctcaa tcggcttcac ttcacgcgct
    11761 tgctcaatct tacgcgcaat ctgtttagag aatttatcct caccgtattt gaagaaaata
    11821 cgaaccaaat catgatagtc atagtgatta accacttcat aggctgtcag actagcatcc
    11881 tgattcatcc gcatgtccag tggcgcatcc tttttataag aaaaaccacg ctcacgctgg
    11941 tccaattgag gactagacac tcccaagtca taacaaattc catcaatttc ctgaacacca
    12001 gcttcgcgca aacgtgcctg taaatgacgg aagttatcct tgataaaggt caccattccc
    12061 ttctcaatgt aaggtgccaa gcgtttttgc gcattgtcaa tggcattctg atcctggtca
    12121 aaggcataga gatggccttt ttcacttaat ttacttaata aatactcgct atggcctgct
    12181 ccacccaaag tcgcatcaac gtagataccg tcaggtttta cgtcaagcat atcaatcgtt
    12241 tcgtggagta agaccgttac atgatgaaat tcttttgtca tatcttatct attttaccac
    12301 aaatccgacc agcttgcact tgtcagacaa ataggacaag gagactacta tttcttcaaa
    12361 aaatatgtca aatatacttg acactttatg tttaaaagac tataatatag tcaaatatat
    12421 acgacataaa tcagaaagga gaccagatga atcgtgtgaa agaatttcgc aaggaattgg
    12481 gtatttccca gctcgaactc gccaaggata tcggtgtctc gagacagact atcaatatga
    12541 ttgaaaacga caagtacaat ccaaccttgg aactctgtct caatctcgcc cgcagcctcc
    12601 aaactgacct caacagtctc ttttgggagg aagattttta aaaaaggagc aaactcatga
    12661 aaaaagaaac cttcactgaa aaactgatca aacgcacata cggtatttct ggtccccttg
    12721 acgaatacaa acggcgtgag gccgatagta ttgggaacca agtctttatc gtcctctttt
    12781 atctgatgat tttcggaaat cttattccac tccttctagc ctataaatac cctcaagaag
    12841 tggctctaat ctatcctcct ctgattttag tgattgccct catcgctgct ggctatgtca
    12901 cctaccaaat gaaaaaaaca ggcatcacag tcattgaacc agatatgctg aatgagaaag
    12961 aaagcaagca actacactac ccaggtctga aagcaggttt gttctttggt ctatggatgt
    13021 tttttataac tcctcttctc agtatactca tagatgaagg tcaggactat tttcattctc
    13081 ttctcactat aagaaatggt gtatcaagta ttctcggttc tattttcttc ggagcgagca
    13141 tacagttcct catctcccgt cgcattgcaa aaactaagaa aaatcaagat gaggattagg
    13201 aggaaactca tgaaaaaaga aaagaaacag ttacgttatc ctggtcttaa agcaggttcg
    13261 atttatggaa cagtgatatt ttttataatt ccactcattg ataccctaac aagtgaaaat
    13321 ccaaatttta tcagttctct tctaaataca aaacatattt ttaaaactat actgggagct
    13381 ttctttttcg gagtgatgat acatattgtc gactcacttc gtattgcaag agctaaaaaa
    13441 gaccaggatt aggaggtgcc ttatgaaatc actagctaga ctactgaaca ttcatgtttt
    13501 tatcagtatt ttccttttct tcgcccttat ttcaggagct gtttctcata cagttttact
    13561 actcctactc ctctttcttc ctgcgctcaa taaaggactt gagaaaatac aatcaaaacg
    13621 gatacctgtc ctcaacgcag ccctcttctt tctcctcata tcctttccac aacttttaac
    13681 caaccctgtc caatggaaat tttcaatatt cctagtcgta accatcattt caagtttggc
    13741 ctacttctat aacttttatc aagtagttaa agaagtagat caaaaacagt tgatttagga
    13801 gcttgctccc ataatttctc atttcataag caaataatcc cacctagctt gttctaggtg
    13861 ggattatttt atttcttaac agagattgca agtcattttc cttcatttta gaaagtcgac
    13921 tctttccaat tcacactaca atccaagact tgttgccttt cttcttgatt acggccttca
    13981 atctgatcaa tcaaaatctt tgtagcctgt tgtccttcct caaaggaggg ctgaaccagc
    14041 gtcgaaacac ttggagaaga aaagcaagtc cactccgtat tgtcaaaacc aatcaaccca
    14101 acttgtggca agttataatt caactctttg ataacggtaa agactagagg tagggcccaa
    14161 cagttaggga taaataccag agttttttca tcgggatcga tttctttttg taaaaattcc
    14221 ttaatttgtt ccaaattcgt atgcttatct tcaatggtta gactggcgtg acgcatatta
    14281 gcatctgtta aagcatccac aaaaccactt gcccgctcaa tccgagtact caaacgactc
    14341 gtatccgctg taatcaagag aaaatgctca taaccttttt cgatacagga ctgggtcatg
    14401 tcataaacgg catcatagtt attggtttta acccagctag tccggtgttc atagagctga
    14461 ctatcaaaaa agaccatttt cttctttttc tcatcgatga tacgagaata ttttcggaaa
    14521 ttagaggtcg gctgaataat aaagccgtct actcccaaga gaagcatgct ttcaatatac
    14581 cggtcctcac tctcttggct gtaattacta tttcctatca ttacctggta gccattctgg
    14641 ctggcgatat cctcaattcc cttaacaatt tggtttgaga aactgttggt aatatcaccg
    14701 atcaaaacac cgattaattt tgttcgtttg gagtttaagc tacgcgcaac aatgctcggt
    14761 ttgtaatttg tttcatgaat aactttttca atcttttcac gtgtctcttg ggacattttt
    14821 tcatatttcc cgtttaggta aaatgacacg gttgttttcg aggtctgagc catttccgca
    14881 atgtctttta tggtcagttt cttctccaat ctaaaacacc tcctactaat acttattata
    14941 acatattcac tattcaaaat gcctatttct agcactgcaa gcgaatcatt ctctcattta
    15001 ttttatcata tactagacat tttccacgca tttttgttcc gtcaacgagg cacaattttt
    15061 cacctacaca aatatcctcg cttaataaca gaatcagctt gtctgtttcg tcatttttca
    15121 cttcaaaagc cagagcattt tccacttcac gatcatctgt ctggtagaca gaatgacgga
    15181 tgatttcaaa actctcatgc gcaatgatgg tataatccag catctgattc tcaaagaatt
    15241 ggcgcttggt gagtttgtta cttctttcaa gctcattgta tttaggagaa atgatggtat
    15301 cttccaaatc aaaatcaact tcactccata gtctcaactg attgattttc ccatcttgat
    15361 aggtcacatc cttgtcaagg ataaactgag tcaacgcctc atgctgacct tgacacctga
    15421 tgtcatccac caagagccag acatcctcta ccaacatgag gatttttctc ttgtgaagat
    15481 aaggcaaatc aggttctgct gaccaataag ccccttcaat ataatgcact ccctcccttt
    15541 ctttatggtg acaaaacagg gagtgaggat agtattcata ttcccaggat cccgtgattc
    15601 tttccggagc tttcccatct acaatgcagg tcgaatgact ccaagcactc tttaagagat
    15661 aacgttcata tatctcccga taagaataac gcccagcatc tatgaaaata ggttgtcctt
    15721 gatactgtaa gcaaaaacta ttctcgtcac tatggctatg ggcacttcct agcggaccat
    15781 ttttgaaaaa tagataacga tgttcatcct taatgcagac atgtccagag tcttcaaaga
    15841 tcatggactt aggctgccaa gctctctttt caaattcctg cagtcgcttg accttttctc
    15901 gccccaggaa caagaggcta agcaaatcga ctttaacatc cagaccgtta agaaggtctt
    15961 ccttgttcaa aaccacagca gacaggctca aaatttctgt cgtttctgta gaatcgctat
    16021 caccaaaagc caaagttcgt ccatctaagc ctgtcatcat ttgaatatag gtcgccatct
    16081 tttccagcaa ctctcggtaa ctatcttgca agtctggaag caagagacac aaatccagca
    16141 aggctttata aacctctaca tgatagagaa tcgactgttc aaactggctt ccatctccta
    16201 aaatctgtgt ctcaatttgc tgtttcaact cctctgaagc aaaatggtaa gcttcttcta
    16261 ggtccatctt atctgaaaag aaataataga tagcaagcat cggaattgtt tgtaaaatcc
    16321 cccagttact aagggtgtac ttggcgcgat agtagctttt cataaagtca atctgctttt
    16381 ctagactgac caaaattttc tctagttctt tctcctctag catgtcaaat ttcaagagga
    16441 gcaagagtag tttcaaccaa gtaaaggaac gaatacccgt atccaaggtt ctagtcatca
    16501 aggattgagg agaaaattct ctcacctgct caatccaatc aaatagaaag aacttgcact
    16561 tttgaatata gtccttatct ccttctacca cataccctat cataaactgc aagagatatt
    16621 cttgtcgatt gagcatataa gcccattctg gatcatcttc aaatacttga tcccatacca
    16681 tcggctggat ttgatggatt tttgaacaag gctccatatc ccaaggacta tcaaacataa
    16741 aacgattgtc catcaagcgt tcaagggaac tcttgacttt ctcatagtct tttgaacagt
    16801 gcgacaagat ataatcacga cattggtttc catcgactct ttcaaaaaat tgtcttcttt
    16861 cttctttcat tatctattac cagaaaaaga actacttaaa aagcagttct tttgtctttc
    16921 ccattacact ttccttttct acatagatga ccacaccttt tgcaatctgc aaggagacca
    16981 agtcatcttt gatagaaatg atttttccat gaattccaga caataacaac acttcatcac
    17041 cagatgttaa agaagctaaa tactcttgtc gttgctccgt ctgtttgcga agcaactttt
    17101 gctgacgaat agaatgaaag cttgacagta aaaggggact cactgccaag acaatcacta
    17161 ttccataaaa caatgttgta tccattaagc tataatctta agccagcttc cgataattcc
    17221 gatgacaact gttaaaataa cgagtttata tgttgtccat ttcttttctt tgatcaagta
    17281 gtaaactaaa agtgtaaata gggctggtag aagagctgga gcaaccttat caagcattcc
    17341 ctgaatactt acgatacttt gtttagcgtc tgctttaact tcccctgcag caaaggtaat
    17401 cggcaccata atcttaacag atgtcgctgc caaaccagca attacggtta caccgataat
    17461 attggcaata cgagaaatcg ttgccatctg ttcgcttagt ttatcaatca cagttgttcc
    17521 tagtttgtat ccatacagac cagttgacaa tttaatcgct gttaaaatcg tattcatcgc
    17581 aaggaagaac aagattggac cgacaaccaa gccttcttga gcaaacgaag ctgcgatggt
    17641 tgagaacaat ggagctaaac agaattgaga aagagaatcc ccaatacctg ccaatggtcc
    17701 catcaaggcc atcttgatgc tacgtgtttc ttttgccgga cggccatttt ccaacattac
    17761 aagatgcaag ctggtaataa aaggcaggaa gtgtgggttg gtattataga attcacagtt
    17821 ttcttccaag gcttggtaga aaccttcctg atcctctcca tagtgttttt tcaaagcagg
    17881 atacatcaca ttggcatatc ccaacccttg atagttacta tagttaaatc cattttgaca
    17941 aaagaatgcc cgcaaagacg ttttaagata atcacgtttt gttaatttgt tagatccagt
    18001 catcgtgtgc ttcctcctct accacatgat tcgctgtttt tggcttgtta taaaattcaa
    18061 tcaaagcaaa gatagtacct acaattgcaa taccaattgt tgggatgttt agataagctg
    18121 cacaaacata tcccaacaag acaaagggaa tcaactcttt cttagccatc actgacaaga
    18181 tcatcgcaaa accgatagct gggagcattt taccagcaac tgtcaaacct gtaagtaata
    18241 ccggtggaat gtagtctacg agtttcaaca aggtatccat tgaaagggca cccaagcaac
    18301 ccaaggtaaa tccaataaag gcaaacaacc aaattgttgc atttagagta aacttgaatt
    18361 tcttcaaatt atggtttttc aagtgcttca tcgccgtttc aggcgcacca gcacgtacag
    18421 tgtaggcgaa agtttgtaag aattgaatcg ccacagcaat cggagtagag agggcaagag
    18481 ccgcttctgg actgacttta ccagcactag tgatagccat caaggtacca aagataccaa
    18541 gtccgattgg gtttggtgga acagtacctc cagcaccaac accgaatccc atataagcca
    18601 attcaccaat agctcccatt gcaagagcag taggcagatc acctagaata attccgacac
    18661 caaatgacag aacaatacat ctattggtgt aaattcctaa cagcattcca ctaaaacaga
    18721 aagctgtcca taatccaatt aaaatcgctt gaaatacatt aatcgacata acgatctcct
    18781 cttttaaata tagtccataa tgttgacttg aacagctcca tcatttcctg ttggagttgt
    18841 tttcgtatta aatgttactt gatgagtttg gcttaattcc ttgagggctg ccttgtcctc
    18901 ttcacccagg aagatggagc gtgtcacttg ctctttacca ggggcattgt gaatgttccc
    18961 aatattgatt tctttgatag ggacaccacc ttctaccaag gttaaagcgt cctttacatc
    19021 ctttacaacg ataaagatcg tttgagcagg attagccttg tgaatgatat caatcacctt
    19081 ttgcaaaggg aagaaacgca tggcaactga gtctggcaca actgttttca tcagagtttg
    19141 ttgcatcttg tccgtgctta cttcgtcatt ggcaacaatg accgtattac aagctaggta
    19201 ttttacccaa agttgtcctt gtccatgaat caaccgttca tcgatacggg tcataataat
    19261 atttggcatt gtcatatttc tcctcctacc aatataggtt ccagtctttg tagaaacgga
    19321 taagggcttc taggtaatag tagtcacccc agatattgcc ttcatccact cctttacctg
    19381 aatgccatga gtacacaccg tggagaagac ttgtcccacc aggggtaaat tgatcatttg
    19441 cataatgttc gatcaaggaa cgaagcatgg catgcatagc atgtttataa atatctttgt
    19501 cagcatccac ctctgggaga tgttttagca tttcatgaat cccacagacg gcgatagctg
    19561 ttgctgaaga atctcgtgat tgagcactac catcattaaa aatcaaatcc caataggaca
    19621 catgatcttt tggcagacga ttcaagaaat aattggtcac acccttaaac aagtcaaagc
    19681 aggactcgtc ttttaagtga cgataagtca aaggaatacc atagactccc catgattgac
    19741 cacgtgccca gcatgaatca tcactatacc cttgtctcgt tacaccttta aagggttgac
    19801 ctgtctcagg atcaaaatag aaggtgtgga aggacgaagc gtcatcacgg attacattat
    19861 tagctgaagc atagaaatga ctttctgcaa tatcgtagta tttttgatcg cctgtttctt
    19921 gataagcaaa gaataagagt tggatattga gcaagcagtc gataatcaaa cggtaatgct
    19981 ctttcttgcc caagtctccc caagcttgaa taaaaccacc tttttcttga tagcgttcaa
    20041 tcaacttatc tgcagctttc aaggttgctt ctctagcctc tccatctcca tttatcttat
    20101 attcagccat acaagacggt gtgtacaaga agccgagatc atggtgatcc aattctactc
    20161 tcttattgac acgatccagg aaagaaagaa catttttatg agcgatgttt ttaaatgcat
    20221 cctgttgact gtattcataa gccaaccaca gttctcctgt ccagaaacca ttggtccatt
    20281 ccgtgttatc catgattgga tagacattat caaaggtagc tggcgtcggg aaatcttcct
    20341 tgaaatagtc aaggttgagt tctaactgcc gaataacctt atcgattgcc tggccgactt
    20401 cttctttcgt cagaagtggt acttctaaga agcgctcagg cgattttatt ttttcaatcg
    20461 taaccttttt tatcattctt ttacccttta aatacccgat tcgaaatctt cttcctctgc
    20521 atccgttgaa aacaattctt taccatttac gactccgccc tgggccgcca ctactgattt
    20581 attaacaacc tcatcaaagc tatgagccat tctagcaaag actgcttcca ttaacatggc
    20641 taagttcaaa cccgagagaa cattcattgt tttgactgga ttttctccca ttatggtaga
    20701 agaaaccttg aatggcgatc ctcccaagag atcacttagg attaaaactt cttcttcatt
    20761 tgaaattgca agtaagattt tttgcttgag ttcatctgct gacattcctt ccacaaagtc
    20821 aatcgcctcc acattttctt gattacctgc aatcaattgt aaagaactat aaatccctgt
    20881 agcaaaatgt ccatgcccta caagtacaat tttcatcttt tctcctttct tgtttaggtt
    20941 taccggttta ctttatattc cccattgtaa tcctttattt ttatcttgtc aatagttttt
    21001 ttaaaaa
//
LOCUS       DBJKQU010000035        20621 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.035, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000035 DBJKQU010000000
VERSION     DBJKQU010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20621
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.035"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(437..2164)
                     /gene="ezrA"
                     /locus_tag="ACSUUC_001442"
     CDS             complement(437..2164)
                     /gene="ezrA"
                     /locus_tag="ACSUUC_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HHQ8054635.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2246..4192)
                     /gene="gyrB"
                     /locus_tag="ACSUUC_001443"
     CDS             complement(2246..4192)
                     /gene="gyrB"
                     /locus_tag="ACSUUC_001443"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HHQ8054636.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKREG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4207..4770)
                     /locus_tag="ACSUUC_001444"
     CDS             complement(4207..4770)
                     /locus_tag="ACSUUC_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHQ8054637.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4855..5409)
                     /locus_tag="ACSUUC_001445"
     CDS             complement(4855..5409)
                     /locus_tag="ACSUUC_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HHQ8054638.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(5420..6643)
                     /locus_tag="ACSUUC_001446"
     CDS             complement(5420..6643)
                     /locus_tag="ACSUUC_001446"
                     /EC_number="2.4.99.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0015648 - lipid-linked peptidoglycan
                     transporter activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HHQ8054639.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6680..9130)
                     /locus_tag="ACSUUC_001447"
     CDS             complement(6680..9130)
                     /locus_tag="ACSUUC_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HHQ8054640.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9330..10259)
                     /locus_tag="ACSUUC_001448"
     CDS             complement(9330..10259)
                     /locus_tag="ACSUUC_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HHQ8054641.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10399..10686
                     /locus_tag="ACSUUC_001449"
     CDS             10399..10686
                     /locus_tag="ACSUUC_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HHQ8054642.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10720..12054)
                     /gene="ciaH"
                     /locus_tag="ACSUUC_001450"
     CDS             complement(10720..12054)
                     /gene="ciaH"
                     /locus_tag="ACSUUC_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HHQ8054643.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12044..12718)
                     /gene="ciaR"
                     /locus_tag="ACSUUC_001451"
     CDS             complement(12044..12718)
                     /gene="ciaR"
                     /locus_tag="ACSUUC_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HHQ8054644.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADFMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12827..15373)
                     /locus_tag="ACSUUC_001452"
     CDS             complement(12827..15373)
                     /locus_tag="ACSUUC_001452"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HHQ8054645.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQHLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15496..15936)
                     /locus_tag="ACSUUC_001453"
     CDS             complement(15496..15936)
                     /locus_tag="ACSUUC_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HHQ8054646.1"
                     /translation="MIPQEMWNKYKQINPSIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVKPFNRVSADHAYKEGE
                     GNKTLVYWRQVHEDFFRDCLGEAGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15911..16780)
                     /locus_tag="ACSUUC_001454"
     CDS             complement(15911..16780)
                     /locus_tag="ACSUUC_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HHQ8054647.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDDDQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16758..17258)
                     /locus_tag="ACSUUC_001455"
     CDS             complement(16758..17258)
                     /locus_tag="ACSUUC_001455"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHQ8054648.1"
                     /translation="MEIKKHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETRFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17269..17967)
                     /locus_tag="ACSUUC_001456"
     CDS             complement(17269..17967)
                     /locus_tag="ACSUUC_001456"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HHQ8054649.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(17960..18196)
                     /locus_tag="ACSUUC_001457"
     CDS             complement(17960..18196)
                     /locus_tag="ACSUUC_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HHQ8054650.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18296..19222)
                     /locus_tag="ACSUUC_001458"
     CDS             complement(18296..19222)
                     /locus_tag="ACSUUC_001458"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HHQ8054651.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19297..20112)
                     /locus_tag="ACSUUC_001459"
     CDS             complement(19297..20112)
                     /locus_tag="ACSUUC_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054652.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20116..20436)
                     /locus_tag="ACSUUC_001460"
     CDS             complement(20116..20436)
                     /locus_tag="ACSUUC_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHQ8054653.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6198 a         4525 c         3664 g         6234 t
ORIGIN      
        1 aacaaagagg ttttagaggc ctatttaccg tgggactaaa gttgtacaag aaaagtgcaa
       61 ataagaaatc tccagattag gaactatccg tgagttctct agtctggaga tttttcaata
      121 gacttcgtta ttggacggtt accaagttac tcaaagtaca gatttgaagc tgcagataag
      181 actgacgaaa tcactttaat actaaatgaa aatcaaaaag caaactaaga agctagcctc
      241 aggctgtact tgagtacggt aaggcgacgc tgacgtgatt tgaagagatt ttcgaagagt
      301 ataaaacact gttttgaggt ggtggataaa tcggctgggt aaaaactcaa tctcaggaga
      361 aaatgaagta aatctcccca caactataga aaaagatttg attctgctcc tcacacaata
      421 aaatcttttt cttttattaa aaacgaatcg tttcacgtgt tttctcatat gaggtaacaa
      481 agcgattggt tacaccaggc tctgccactt ccaatgcttg agaaatcttg tcaaatgaag
      541 cgtgataatc aaattctttt tcaaaaatat ctaaagcttc gttaaatgct tcttgaatgc
      601 gttcatcaaa tgagcgatag cggttagaat attgcaagag ttgctctgtc aaagttgcat
      661 attgtacaat attataagtt tccgtttcta aagcttccat atcattcgtt gcaatttcaa
      721 gaactcgggt aacagattca atgttaatca ttttttgttc taactcaacc attaaatcct
      781 cggtattatt gcttgccgta aagaataact tcaagaaagt ttgtggaata cctggcagat
      841 tgcgtttttc catgtatcgc ttgatagtat ggagacgatt gacataaaca ttggcctttt
      901 gacgtgcatt aatatcatct ttctcaattt gtgtcaggcg ctcactaact gaaatttgct
      961 catcttcaat atcttttagt tgagtttgta aatcctcaag attttcttca agaactgaat
     1021 aagcttgggt tggttcttct tgattcgaag ttacctcaac aatagctgcc tcaaaactct
     1081 ctaattctgt ctgaatacga cgaacatggc ttgcagctgt ctcaggaagt aaataggtct
     1141 tgttcaaacg tgcaatatct tctcccaata aagtattatt ctctttcata tgttgaaggt
     1201 aagttggaag agttgcaagt agattttcca ctactttctg agcagcaatt tctcgagtaa
     1261 aaatatcata caaggcattg atttcctctt gtgcctgtcc attctcatat tcggcattat
     1321 ccaattccaa ctgacgaata ttctcttggt ttttcttgaa tgcttcataa agcaagtgga
     1381 aacgcgcttc aatatccgtt tcaacaaaat gataattagc atcaattagt ttacgataac
     1441 cggcttccaa atcctgtaat tgatctggca attctgtaga aagcgtcgta accaaggctg
     1501 gaacacgatc cacaatatga cttaaggcca aaatgtgatt ttctgtatta tccaaaatca
     1561 ctgcggcttc cacagggtca cccgatgaat tcaaggttac aaattgtgaa aattcagatt
     1621 ggatattttc taattgtttt tcaatttcat ccaaggcttg accatactgt tctgaatttt
     1681 cagcaactct atgctgaagt tcctcaaata aatccaaagc atgaagaaca cgaccactat
     1741 ttttagattc ttgcttctct aagtctgcca aagcattgcg aattgccgca atatcttctt
     1801 caatcaaagt aatttgactc tcaatttggt caatttgatg actggccttg agaaaacgaa
     1861 atgaatggtt atagccttct gcttcaaaga gattattttc aatatcggca aaagagttga
     1921 gagataaatc gacccatttt tgattccatt cacggaaagc cacttgactt tgtccaatca
     1981 agtgcatatt ttttacagct tctacttcat catttactgg aagattgtat agttcttctt
     2041 ttctttcttc tagcgcctct aatctcccct cgtttcgctt acgtagaaag attgccacta
     2101 cataagccag aactaaaatg actgcaattg caaccattaa ataaattagt tgtccattag
     2161 acatatcaaa ctcctttttt acttgaaaca atcgtaacga ttatatcata ttttttagac
     2221 caagggaact acttctccct attttttaga catcaagtgt actatagaca gcattttctt
     2281 cgataaactc acgacgaggc tctactcgat cccccatcaa catatcaaag attttatctg
     2341 cttctgcagc atcatctaca gaaactctag ccatcaagcg atgttcggga tccatggttg
     2401 tttcccacag ctgatgatcg tccatttcac ctagcccctt ataacgctga atagtcggtt
     2461 tggtacgacc ttcactataa cgggctaaag cttcttggag tttgatttct tgatctgcac
     2521 ccggctggat atattcttta atctcgcttc caaccttgac accatagatt ggtggttggg
     2581 caatataaac ataaccagct tctaggattg gtttcatata acgataaatc aaggttaaaa
     2641 gaagggtacg aatgtgggct ccatcgacat cggcatcggt catcaaaacg agtttttggt
     2701 aacgggcttt cgaaacatca aattctgcgc caaatcctgt tcccatggct gtgaaaagac
     2761 tacgaatttc ttcgttagct agaatcttat ccatacttgc tttttcaacg ttcaaaatct
     2821 taccgcgaat tggaaggata gcctgaaact cacggttacg accagatttg gctgatccac
     2881 cagctgagtc tccttcgacg atgaagagtt ctgtttcagc agggttatta gaagaacagt
     2941 ctgctagttt ccctggaagg ttggaaattt ccaaaccaga ttttttacgt gtgacttcac
     3001 gcgcacgctt ggcagccaca cgagccttgg cagctaaaat ccctttttcc acgatacgtt
     3061 tggcaatctg tggattttcc atgaggaaat cggagaaggc ttcactgaag aggcgattgg
     3121 taatcttgac cacttcgcta tttcccaatt tggtcttggt ttgtccttca aactgtggat
     3181 ttgggtgttt aactgagata actgcagtta agccttcgcg aacatcttcc cctgttaggt
     3241 tgtcttcatt gtctttcagt aacttatttt tacgagcata atcattgata acacgtgtca
     3301 aggctgtacg gaaaccttgt tcatgcgttc caccttcatg tgtatgaata ttattggcga
     3361 aactcatgac attttcatgg taaccagttg tgtactgcat ggctacctca actgtgatat
     3421 catccatctc accgtctgta tagattggtg tatcaaagat tacatccttg ttctcgttga
     3481 tatattcaac gtaactagca atcccacctt cataatgata atgcttggtt tgttccaaac
     3541 cttcacgctt atctgtaatt gaaatttgaa gaccgcgatt tagaaaggcc aactcttgaa
     3601 tccgtttatt taatttatca aaatcaaaga ttgttgtttc agtgaagatt tttgggtccg
     3661 gtgtgaagtg aacagttgtt cctgttttat ccgtatctcc aactatttca agatctgcga
     3721 caacatgacc acgacggtat tcttggtaat gaatcttacc atttttgtga acatgaacgt
     3781 ctaattgagt ggaaagggca ttaactactg acgaccccac cccgtgaaga ccacctgaaa
     3841 ccttgtatcc accaccgccg aactttcctc cagcgtgaag gactgtaaag acggtctcaa
     3901 cagcaggacg gcctgttttt tcctgaatat cgactgggat accacgccca tcatccacaa
     3961 cagtaatcga atcatctggc tcaataaaaa cttgaatatg gctggcaaat cctgccaagg
     4021 cctcgtcaat tgagttatca acaatttccc agactagatg gtgaagacct tcttttgagg
     4081 ttgatccaat gtacatccct ggacgcatac gaacagcctc taagccctct aaaacttgaa
     4141 tttgactggc atcataatcc tgtgcctgca gatttttgat ttcttctgtc atcttattcc
     4201 tttttcttat atgtctaata cttgtcttaa attcacgata ctggtaaaca agtgggtatc
     4261 aagtcctgca gcttgacctg cttcgatatc aatcggccga tcaccaatga caagaccaga
     4321 gctaatctga tacttttctc ttaaataaag catggattcg ggatttggct ttctcttaaa
     4381 gcctgagcta gaagtcacca cttctgtaaa ataagctgct atagaggttt tttctaaaat
     4441 ttccaaaacc tgatcatttc gatgagagac caaaaaatga cggccacctt gatttgaaat
     4501 gacttccaat aggtcagaaa ctccttcaaa taaaatcggg tgttcaagct ctctggcttc
     4561 attttccttg tacttttcta aaaaattctc taaattggga gcgaatgtct caatcgcaaa
     4621 aggagtagaa acctttaaag cttgatagac actgtcatgg tcttgtgtga taccatacag
     4681 tgccaatgtt tcaacaaatg cagctgttga agtttcataa ttatccagta aagttccacc
     4741 taaatcccag atgtaatcgt gatatttcat acccttcatt atagcatttt tttatgaaaa
     4801 aagcgatgat ttccctgagt tttccacata aaaaacgaga gaataactcc cgttttactg
     4861 atttttacca aagacatctt gatagagcat tcctgttcgt aaactctctg cgtcccctcc
     4921 tagttgctcc accaactcgt aggcaaaggc aagggctgtt gaaggacccc gactggttgt
     4981 caactgacca tctaccacta ctgtttcctt gacatagtga ccatcaagga tttgctcttg
     5041 aacgccgtca taacaagtgt atcgcttatt tttcaatatc tctgcttgat tgagggcaat
     5101 tggtgccgca caaatggctg ctagtttctt cccttcttgc tcgaagcttt gcaattcttg
     5161 aatcaaggtc tgattatcac gtaaatgtgc agaaccaggc atacctccag gaagaacaat
     5221 catatcatag tctgataaat ctccatcaaa gacatgatct gctcttactt ggattgcatg
     5281 cgaacccgtt acttgctctt caaaaccaac catatcacat gtgatattgg ctcgacgcaa
     5341 gacatctaca actgtcaagg cttcaatttc ttcaaagccc tgagctaaca taactgctac
     5401 ttttaccatg attttctcct tatttaattt gttttaatac aacctttttc cgtttgaatg
     5461 ggacttttcc gctcttttct tcagctagat tagtctggta actcatcgat aaaagcaaac
     5521 caacaccaat cagattactg ataatagctg atcccccttg cgaaatgaaa ggcaagggaa
     5581 tccccgtcaa aggaagtagt ccagtcacag caccgatatt ctcaaagatg tggaagagca
     5641 acatcataat caaacctgtg gaaatataag tgtagaactg gttatttgat ttaagagtaa
     5701 tcttcaacat acggtaaatc aacatgagat agagggcaat aaccaggaca gagccaataa
     5761 agccaaaatc ttctgcaata accgtaaaaa tcatatctga ctctcgaact gggataagca
     5821 gattcgaagc attaaatccc tgaccaaata agccaccact cccaatggca atctgccctt
     5881 gagcctgctg gtaagtcgtt gtttgggcaa actcaaaggg attgagccaa gccaaaatcc
     5941 gattaatttg gtaggtcggc attccaatct ggtgaagaaa agctcgtccg tccttgctaa
     6001 taaagatagc taagaaacca gcaactcctg ttacagcagt cacaaatact gggataataa
     6061 ttttccaaga aacccctgat aataaaacga ttcctgagaa aatggctaca aaaaccaaag
     6121 ccgtccccaa gtcactttga agtgctaaaa gaactaggac tggaatggta aagagaatca
     6181 tccagaaaat taacaaaaag tccagcggaa ccgtgcgtct ccattcctta tgtttctttg
     6241 taaattggac aatgacacga gccaacatga ggatatagga tatcttcata aattctgacg
     6301 gttggaatag ggtaattcca tttattgata cccagttttt ggcacccgtt gatgcaacta
     6361 agcttggatt ataaaataca atcggcaaga tcataagtcc caagcctaaa atatatagaa
     6421 agggggtcac cttccaaaga aattctgtat taaagagcat gaccacaaaa ccaatcacaa
     6481 gccccaaagc aatccaggcg acctgctgcc ctaaaatggg cagaatatta ttgggataat
     6541 catgactaac ggctatatag atagccacca caccgatgac cagtagaaaa aatactggca
     6601 agagcaaact gtaatcgact cttgagtcga gagaacgttt catatatact aaccttatac
     6661 tttcatacaa tactatttat caaagttcat taaaaaatct atcaatagcc tcgtcaactt
     6721 cggatcgaga gatggtttta acagtcgctt cttctgctag agatgctact atttgtttgc
     6781 cgtatcgttt tccgacgatt ctcctatcca aaataagagt taaggaacgt tggtattcac
     6841 gtctcatact tcttcccaaa gcctgtttta aacgaataat ggccattggc aattgataat
     6901 cataaaaggc atttttccct tcttgattca gttcttgatt aatctttttc gtcaagggtt
     6961 cttgaggatt ttggaaagga agcctcggta caacttgaat cacaaaagga tggcttgaaa
     7021 aatcaactcc ctcccagaaa cttgctgcac caagcaagat ttgttgttca cctttttcaa
     7081 agcgtttctt tagctgatga acatccccat ttttatactg ggccaagtgg ctaactgtaa
     7141 gtaaatccga tactgctaga agcatgtctt tagcggtaaa gagaaccaaa atcggttgct
     7201 ggaaagcttg aatttccact agtaaagcag ctacctctct ggcatagact tctaaggagg
     7261 tttctgttac cagagggaaa tctttgacca tgaccacttc ttgttcctgt tttccccgag
     7321 attcaatctt gacaaatttg gcttcaggat agcctaaaag gtctgccaaa gaaaccctct
     7381 gactaatctc aagagtagct gatactccca agacttggca actctcagga agtaaagagg
     7441 acagaagagt acggcctgat tttgtagaag aaatctgaat tttcttttga ctcgtttcag
     7501 ttacttcaag ccagtaatca ccttcagctg taaaatagcg aaccagctca tcaaagcctt
     7561 ccacttctaa ttctgaaaaa tactgatgga gattgtccag agaatctaag atatttttcc
     7621 tagatttgcc agactgaaat tgttctatca agtagagaca ctcaaagcga atactttcta
     7681 gtatccgttg ttgaaccctg ttttcttctc ctactaaagc cttatcaatt aaatcgataa
     7741 tagattgtat atcgtaggtc tcttgaagca gattttctag agctaacaaa atcttttgga
     7801 cttcatcaat aatcagtaaa cggtcactga caaattcagg attatcttca agtctggtca
     7861 cgagataggc atgattagtc actaaaagct tgcaagtctc tgccctttct tgactacgtt
     7921 tccaaaaatc ttccgtcaca aataagctct gggatgataa attcccatca tgacgaaggt
     7981 ctgctagaaa atgttggtaa cggtagagtt gcccgatttc atccaaatct cctgtctctg
     8041 tctcagtaag ccagaccaag acttgcattt taaagcgtct aaataagcga ttttcatcat
     8101 tttcctgcaa ggaatgataa aaggcatcca acttcagata attttgtggt ccctttaagc
     8161 tatgaatatc tgtatggaac acttccttga gacgtttacc ttcttcttcc atgatttgat
     8221 tttgaagaat ctttgtcgga acactaagaa caatttgtcg ctctttggat tgagataaag
     8281 cgggtaagag atagccatag gttttcccaa tccctgtcgg cgcttgaatc agagagacag
     8341 gttcatcttt caatagcaag ccaacctctt tagcaaaact ttcttgttcc tccctcactt
     8401 caaggttcaa cagagaaata tttttagaaa agtcttgaga tagttttcgt agctccagag
     8461 aagctgccgt tttcttaaaa tacagacctt gaacttggac caagtctgga gaactcagga
     8521 tagattggtt gcgataagtt tcctcaataa ccaggtagga ctcatatagg agagcgtcag
     8581 ccatttccag caagcgttcc aagagacctt taggaagctg ggtcatcttt tcccgtaaaa
     8641 aaagaagtaa ttctgctgta gcttgggcat ctgaaagggc tgtgtgtgcg tgtttaagag
     8701 gaattcctaa ttctcgacac aaaatcggca agctatattt ttccagttca gggaaaaaga
     8761 cctgggccaa ttcgaccgta tcaacacgag ggtttcttag ctcatagcct tcaaaaaata
     8821 aattttccgc caagagatta gcatcaaact gaacattatg ggctacaaaa atcccatcct
     8881 ccaccaagtc aaatattttt ctggcaactt gcgaaaaatc aggtgcttgc gccagacgtt
     8941 ggtctgtcaa tcctgtcagt tctttgatat gagcatccaa gggttcatgt ggattgacat
     9001 ccgtcgtata gtgatcgacg atttctccgt cctcaatcac gacaattccc acttggataa
     9061 ttttagcctt actacctgtg ctagttgcct ctaaatccac cacaacatag cgattaccaa
     9121 tcgttttcat tataaaaaat tataccaaaa aaagggccat ttggcacctg caaacatagg
     9181 ataattttca aactcaagaa cactactttt cttaaaaatc ccatcgaata gagcattcta
     9241 gcctgctgat ttttgtaaaa tagtgaagaa atacgaaaaa ttgagagaag aaatgtttgc
     9301 atcttccttc tctcaacgaa tcatgtattt tatctaacca tgtcaggatc gtagtcataa
     9361 aatcctgtat caaggaaacg gtttttaggg tgaagtttac gaacttcttc atccagcaag
     9421 aaggcttgat catggctaaa gttgccctct tgaatcaaat tacgcgcttg gataaagagt
     9481 tttgcaatct caacaaagtt ctgaccagga gtgtagagcc cttctagttt ccagcgagta
     9541 aagccatgct ccaccaattc tgttaatttg atcatcaaat caaggtcatt gttggcaaag
     9601 atatgggtcc catgattatc ttcaaaaatg gaatagtggc tctctggatc acttggctca
     9661 gccaagaaga ggtcacgttt atgcgtcttt tcatcatcga tatgtgtaaa gttatagtag
     9721 ttttgcaaga gtggacgttt agaatgatgg atgacgctag caccgtaaac caaaacttca
     9781 gcaggaattt ccaaaatctc tggcattttg aaaagttcag ctgatggaat ttcacgcgcc
     9841 aaaacagcct cagatgcgcc agccttttgc ccccagaagt taatctgacg actgctagtt
     9901 accatggttg aagcatcgta gatggtctta aatgaataac catcgcggtt aactacgtaa
     9961 aagacgcctg catccccaat cgtaatatag tctgtcttga tttcttccaa gaagtctaag
    10021 aaaggcttga tacggtccat catatcttgg tgcatgagag cattgaccgc aacgagcaat
    10081 tccttaccag catcatgaac caacttagcg atttcacgta attggtcata actaaaggtc
    10141 gttggcagac gaaggccaaa atctttctca ccgacataga tacggtctac gccagcttcg
    10201 agtagttgtt caacttgttc aatactttca gcagttgctg taatgacaat cttttccata
    10261 agaaaaatta taccacattt ctccaaaatc agccatgctt tgaaaatgaa aagggacttt
    10321 attctttttg taacctttct gtaataattc tctgccgaaa aaatgataaa ataggtatgt
    10381 actgttaagg agagaatcat gcccgtaaga aaattacaat cctatgaggt agactatcaa
    10441 gaagaattaa accagcagct tcctcattac caagcttata cacctgaagc gcaatctgat
    10501 gccaatctca aggaaatcct attttttatt aatatcgctg ttttttgtat ctgtattgct
    10561 atctttagtt ttatcttttt agcattaaaa ttatcaactg ctcttgcctt tgccgcagca
    10621 atcggattca gcttacttgt tttaaaagtt caacggtcta ttatcaaacg aaaacgtaga
    10681 agataaatcc aaaatatcgc cccaattgga gcgatatttt tattttttct ttttagatgg
    10741 tgtctgaatg gcaatcttca cttcaaagat tgttcccttg ggtttattat ctttgacagt
    10801 aacagttcct tttagagcat ctacaatttg cttggctagg gataatccta aaccaaaacc
    10861 acctttttgc cgggttctag ctttgtctac tcgataaaaa cggtcaaaaa ttttcttttt
    10921 atcttctgtc gaaataccga ttccattatc agaaacaagt aaataaagat tgcgatcggt
    10981 cgccgagata agaaaatcaa tttcaccatc ctcctcagta tacttgacgg cattatcgaa
    11041 aagaatggtc atcagttgtt tcagaagaag ctgatctgtg acaattgttc gatggatacg
    11101 attttcaaaa cggaagacac gattattttc cgaagcaatc atctcgtagt ttgtgaaagt
    11161 tgtattaaaa aagctagttg gaacttctgc aagctccggc ttaatcccat catctctccg
    11221 agctaagttc agcaagcttg tcgttaaaaa acgcatattt cggacttctt ccaaactcga
    11281 tgcaatgctt tcgctcacat ccataatggt agcttctggc ttacgaaaaa gggtctctaa
    11341 gcgattttgc aaaactgcga gtggagttcg taactcatga ctggcatttt ccacaaaaga
    11401 ctgttgcttc tgcatactct caagcagggg cctaacactg accctagcta gatagagact
    11461 ggcaagtaaa gacaaaatcc agaaactagc catcacgacc acaatcaatt gctcatgctt
    11521 ttgactagcc tgctccaact gactggtatt aatcaagaca gcagcatact ttatattggt
    11581 tgaaaccgaa ctaatattgg tctccatcaa aatcacacga tagatttctt cctgcccata
    11641 gctattaaaa acctgaatct ggtagatatg tcctagttct ttcttttcta acttaatctt
    11701 atccaagccc aaaaatcgat ttccagaaag aagttgagta aagtctttat caaagagaat
    11761 gacttccgta ttggaactga cattaggttt tatttctact ttactagcgt ccgccctagc
    11821 attttctaaa tctttaatct cttctgttgc cctatttata gccagctgaa taactgcttg
    11881 aggattttca ctcagtccat gaagcttatc gtccaccgaa gtataaagac tcgaatgcat
    11941 gacttgtaaa ataatcagag tcattgtaga aaaaatcagg gtgaagacac cgaagttgcg
    12001 gataaaataa ctaaagtcat ccgcatacca tgttttttta agtttactga acatctttta
    12061 aaagataccc aacactacgc aaggtttgca aattctctgc aaaagtggtt ccctttaatt
    12121 tcttacggac ttttgaaaca tagacttcga caaccgaaat cgttgtatca ctatcaaatc
    12181 cccatagacg gtcaaaaatc tgcgtcttag gcaaaatcac attttgattt tgaaggaaat
    12241 aaactagtaa atcgaactct ttccccagca attcgacagg agtatcttca actttaacgg
    12301 tattggttga taaattaacc acgatattcc cataagtcaa ggtgttttca ttaaacttcc
    12361 ctgaacgttt gagaagggcc tgaatccgca ttttaagttc ttctaggtag aaaggtttgg
    12421 tcagataatc atccgctccc agttcaaatc catgtccctt gtcatccaaa ctttccttgg
    12481 cagtcataat cagaactggt gtcgtaattc ccttttcacg caattctttt aagacttgga
    12541 aaccattttt ttctggcaac atcaaatcca gcaaaatcaa gtcatagaca ccactctcag
    12601 cttcgtagag accttcttct ccatcaaata cctgcataaa atccgcaaaa tcgtctaaaa
    12661 agtcaaatac tgaatttgac agacctaggt catcctcaac caataagatt tttatcatga
    12721 gaaactcctc cttattaaaa ctattatacc aaatttgcct taaaaaaaac tcaactctct
    12781 gcattttaca tgagatagct gagttttctt tttattttag gcttatttat gcatttccgt
    12841 attgaagaac aactgcttcg actgcagctt tttcacggct aatcaagtca acacgcgctg
    12901 caatttcctt gattcccata ccgatgttac ggctaagagc aaggtcagaa agttgcggct
    12961 caaagaactc cttgtattcc gccaagtgtt gctgagtctt aaatacatga gcaggaagga
    13021 taacaaagct atcaaagctc atatctcctc caagggctgc cttaatccaa gcccagtttt
    13081 cacgcgccca agaccaagct gttttctgag ttgcttgatg agctaggaat tggtaatacc
    13141 aagcagacaa gtcctgtggt ttgaccacaa atttgtcctt ccaagaagta atcaagtttt
    13201 ggatattatc cgcatctgta ctgtatgcaa gagctgctgc caactggcgt ttaaagacag
    13261 catctgttgc gtgagtataa gtatcaagat aaagtgctaa caagtcttta gtctcatgat
    13321 gtttcatctc attaatcaga acttgtgaac gaatagctgc tgggagtcct gcaagattct
    13381 ccttgtgtgt tgcgaagatt tggctagcga cttgactagc ttctgcatca tttgagcgaa
    13441 tcatcatcga aacagccagc tgacgaacca attcatcctc atctgattct ccgtctttag
    13501 cttcaaaacc aagacggtca tagttatgac gagccaattt agcaaccagt cctttgaagg
    13561 ctgtttcagc atccgttcct tcatcaataa agcgctcaag ggctgaaatc acttgagaaa
    13621 cagctgaaac caccagataa gactcttcct tagcaagttt atcaagaact ggaagcaagt
    13681 ctgcataaga aatgtgccct gcctcagcca acaaacgacg ttcttgaaca atttgcagtt
    13741 tgcttgtgtt atcaagtgtc tctagctcag caagaacagc ttctaacaag tctccttgat
    13801 agtcggtaat atagtgggca gtattttcag tgttgagacg aagagctcct tcattttcag
    13861 caagaagagc tgcgtagcca gggatttcga tactttcagt ttcgagtgta tcaggcaagc
    13921 ctttccagtt gctattgagg ggcaccaccc agagacggtt cttgtcttcg ttctcaccga
    13981 tgaagaattg tttttgtgaa atcttcaaga catcattttc aactttaaca gtaagaactg
    14041 ggtaaccagg ctgttccaac caagaatcca tgaaggctgc gacatcacgt cctgacgctt
    14101 gaccaagggc atcccaaagg tcactaccaa tggtgttgct gtattggtgt ttttcaaagt
    14161 aggcgtgcaa acctttagca aaatcagcat ctcctagcca acggcgaagc atgtgcatga
    14221 gacggcttcc tttggcatag acgatagcgc cgtcaaagag tgtattgatt tcatctggat
    14281 gtttaacttc gacgtggaca gactgaacgc catcagtagc gtcacgttca agagcaagag
    14341 gtactccacc tgtttggaaa tcttcaaaga tattccagct tggttcgatg gtatccacac
    14401 agacgtattc catcatatta gcgaaacttt cattgagcca aaggtcatcc caccatttca
    14461 tagtcacgag gttcccaaac cattggtgag ccaattcatg ggccacaaca agggcaactt
    14521 gttgacggct agcaaatgta gagttctcat cgacaaccaa gtaaacttca cggtaggtca
    14581 caagacccca gttttccata gcaccagctg agaagtcagg aagggcgatg tggagagatt
    14641 gaggaattgg gtacttaact ccatagtaat cttcgtaaaa ctcgatagag cgaacagcga
    14701 tatccagtga gaaatcaaga tttgaaagtg gatgtgcttt ggttgagtag acacctacca
    14761 gggtaccatt tttagtttta gcggtcaccc cttgcaaatc accagcaaca aaggccaaca
    14821 agtaagaaga catgcgaggt gttgtctcaa acttccagat acctgtttcc ttacggtttt
    14881 caacatcgat ttctggcatg tttgacaagg ccaattcacc ttctgcttgg tcaaagcgaa
    14941 gagagaggtc aaaagttgct ttggcttcag gctcatccac acatgggaaa gcttcgcgcg
    15001 caaaatggct ctcgaactga gtagacaaga cctccttctt gactccatca actgtataat
    15061 aagaagggta aatccctgtc atgttgtctg taattttacc agaaaaggca agaaccaatt
    15121 caacttgacc agcctcagcc aattcgatat gaagggcttc attgtcatgg tcaactgtaa
    15181 atggacgagc ttgacctgca acttctacag aggtgatttc caaatctttt tggtggaggg
    15241 agatgcggtc actctgtgct tgaccagtga tggtcacttt cccagaaaaa gtcttggtct
    15301 cacgactcaa atctaaaaat aaatcataat gttcaggaac aaattgctta ataaaatgtt
    15361 caactgcttg catagttttc tcctattcta agtttaagag ctgctgctct tcttcaaaca
    15421 aacttattat atcatatttt gcttgagaaa aaaggattgg acagcgattt ccaaaacttt
    15481 cttccttcta atagtctaca gtgggtagac cttgcgaaat tcttctaaaa caaccttgct
    15541 ttcaggtgta aaagtcaatc ctgcttcacc caagcagtct ctgaaaaaat cctcatgaac
    15601 ctggcgccaa tagacaagtg tcttgtttcc ctcaccttcc ttataggcat ggtcagctga
    15661 cactcgattg aagggtttaa cagaaacctt tgtaatttcg acaatgcaga cagcctgatt
    15721 ttgactatct aaaatgacat cgaaggtccc tacttgggga agtggttcgt cttctagtac
    15781 atagaggtca taggctgatg ctgttgctgt cttttctcct ttaaacacca aatccgctaa
    15841 aaggtctggt tcaactccaa aagcccaggc atcgatttca tctccgatag aaggattgat
    15901 ttgtttgtat ttattccaca tttcttgcgg tatcatgggt actcctttgt aattttttac
    15961 tttcttcttt tatgtgttta agatgatctg gatggtcaat ctctaaatca aaaatctctg
    16021 gaatagaact gtagtggata atgcacttga tacccaactg attcattttt tgtatgaaag
    16081 aagtattcag atagcctgct acagcaaaat taatcttgtt ctttcttgct ttatcctgca
    16141 tatctcttag catatctaac attattggac tttccatatc atgccattga ctgtttctca
    16201 tagtcgcaaa aacaaaggaa gtcaaatcat tcattccaac tacaatcttt gaaatgcccg
    16261 tttccagtat actagataag tcaaaatacg ctgacggtaa ttcaatcatc gttccgactt
    16321 tcccagtaaa accctgctga cgcaatactg taatagcttg ttttaattgg tcgtcatcat
    16381 tgacaaaagg aaagataaca gatagattgg ggttggtttg ataaacttct gtaacgacat
    16441 gtgcttcagc ctgaaattca tccaaacacg ccagtaaacg cctggttcct ctatagccaa
    16501 acaagggatg cccttcgtca aaaaactctc tagtccccac taaacaattg gcttctgtat
    16561 tcgttaattc agaaaaacga taccaaactt cttcatctga gtacagggag cagatagtct
    16621 ctagataatc ttttacaaat tgctgacaac ttgctaatat gatgttttga ttaagctctc
    16681 tcaacaaata ttccccacga atcatgccga cgtggtgaaa tagttgagga taaatttttt
    16741 caagaatttt ttcgccacta agggcaagtt gatttctcat cattcacctt ccaattcatg
    16801 taagaagtct tgtccagttc tggaaatcct aataattcag acttaacctt caagactaat
    16861 ggcgatgcat tttcttctgt aatttcttga atatccatcc aaatatatcc aagtgaatca
    16921 ttcgcaccat cagacacagc ttccgaagtc gtaacttgag gtgcactctc attcatttca
    16981 acatcataca aggccatgac atggtgaacc ataaaatttt ttaactcttc tctgacgaaa
    17041 acatcgtaga ttcgaggatt agagtagctt ctaacagtaa atctcgtctc ttccataact
    17101 tctctagtca gcgtttccgt cagtccttca ccaagttgct gactgcctcc aggtagatca
    17161 taccgatgtt gataagggcc tctcgttttt tcaatgcaaa gtaactttcc attttcaaag
    17221 caaacacagt agaccccaaa gtgttttttg atttccatcc aactcctcct acttcaaaga
    17281 ccagccacca tctattgtca agatttgtcc ttgcatggcg ctcgcttttc cacttgctaa
    17341 aaaaagacta agctctgcta tttcctctgg ctcaatccag cgcttgattg gggtttcact
    17401 agccacccag tcagccaaac cacctggttc aaaatccgca gcggtcatag ctgtcttgac
    17461 tgctcctgga gcgataccaa agacctgaat cccagcttca gcatagtcta gagccaactg
    17521 cttggtgaag ccagccaagg catgcttgga tgaagtatag gcgtgaccac ctccacctgc
    17581 taggctagaa gcaatggaac acatattgat gatgattccc tttttatttt ccagcatttg
    17641 tgtcaaataa taccgagtca actctactgg aataatgtag ttgatttcaa aaatctcttg
    17701 aatgtcctgc gccgtttgtt ccaacagtgg tttgtaatca tccaaaactc cggcagtatt
    17761 acacaaaaca tccacctgag ggcaccagtc aaaaataggt tccaagtcca aggtcaaatc
    17821 tctctgtaaa aagtgaaaat caccctctaa gagtggcttt tcaccttggt caactccata
    17881 aacttgatag cccttctcta aaaagaggcg agcttgagcc aatccgatcc ctgaactcac
    17941 tcctgtaatg agtacacgtt tagtcatgca cttctaccca atccgttgcc aaaacatcac
    18001 aagctgtcgg gctccacatg gaaaaacctt ctccttctcc agacacgttg attaggaaat
    18061 aaggtgtcac ttcaagtgca agcccatttt gctcgatggt atcaaagagt tggacatagt
    18121 tttccgcacc tccccaacca gttcgtacat attttttctt agcctttaag ccaggtaaaa
    18181 tttcttcaaa tgtcatgttt ttctccttta atgtcaataa ttctcccctt cattataaca
    18241 aaaaaaccgc tttaaaacgg ctttttgact gtgatttatt caaacctgct actacttacg
    18301 gcaaattatt ccctgcagca agataaattt cataccattc ttttcttgtt aagctaaagt
    18361 ttgccgctcg gctaacttct ctcaagtgct taggatttgt tgtacctacg actgcctgca
    18421 tttttgctgg ataacgcaat atccaagaaa tggcaatagt tgaagaggtt actccatatt
    18481 taatagctaa acgatcaagt acttgattta aagcttgaaa tttctcattt ccaacaaagt
    18541 tccctttaaa atacccgaat tgcaagacag accatgcttg aatgaccaca tcgtgtaatt
    18601 tgcaatattc aaaaatgctg ccatctcgca tagctgcttg actatcttcc atattaacat
    18661 gaaaagctga ttcaaatcct ggagtaaaag ccgcactcaa ttgtagctga ttaacagcta
    18721 acggctgctt gacatctttt ttaagcaact ccatcatcat aggattttga ttagaaactc
    18781 caaaatctcg aactttacct tgtttataaa ggagatcaaa ggcttctgct acttggtcag
    18841 attccatcaa agcatctggt cgatgaagga gcaagctatc tagatgatca atcttcaatc
    18901 tttgcaaaat accgtctact gattttataa tatagtcctt agaaaaatca aaataggtaa
    18961 attcttcaat gcgaatgcca catttggact gaatccacat cttttctctt aaatctggac
    19021 gattttttag gacaagacct aacagttctt cacaacgacc acgaccataa atatcagcca
    19081 agtcgaaggc attgattcca acagaaagtg ctgtttctac aagctcttca acttctttta
    19141 cagacttatc ttttattctc atcattccga gaacaatttc tgataattct ttgtcatctt
    19201 gaccaagagt tatgtatctc atcaaatttt tctcctttaa tttctaacat tcttcccttc
    19261 attataacaa aaaaccgctt tgcaacggct ttttgactat acttcactcc attttatctt
    19321 cttaaaccca cggaacaaga caaagattcc aataaagagg acagctaaag gaataacttt
    19381 tgtaaggaaa acatttgaaa ttcccatcca ctcataataa cggagcagag aacccaccac
    19441 aagatgggca ataatcatac tgacaaatgg acgaaagacc gcttctttcc aattccaaat
    19501 accgataact agcgaaatcg taaagacaga caaactatcc cagggagccg gaatataaaa
    19561 ggctccttct tgtatgaagc ttgccattcc tacatatcct aaaacaacta gaagaactat
    19621 agtcccaaca acaatgtaag tgccaatttt cattttagga gaatcttgga ctaaacttct
    19681 tcgtaaaatt gtggccacaa gtccaaatcc aatcagaaaa ataagaagtt gccctaaaaa
    19741 tgtgagcaaa ttgactgtta agagaggacc tttagaaaaa tcacttagta gttgataata
    19801 acgtaatacc gccaggacaa gaattggcgt caaaagggac tctttgatag aactgcgagg
    19861 tgctcccttg agaatctctt tcattatttt tttaggattc ttacctagat aatcctctgc
    19921 actcatgcca tctcgttctg cttctgagaa atctagcatc atcaaataga tctgctctct
    19981 gagatagtct tcatcataga gaaatccagc aagattaaaa ctttcccaca actcctcaaa
    20041 atacttttga ttctcctcag aaaactcatg tagcaaagcg cttgtttctt cgtaatactt
    20101 cattttcttc atggtttaac ccccattctt aatcccttct actttttgac tcaaatcgtc
    20161 ccattgttgc caaaagactg agacacgctc ttctccttct ttcattaatg aaaaatactt
    20221 ccgatctgga ccatctggcg acgggcgcat gtcgcctctt atccattgat ttttttctaa
    20281 cttttgcaac aaaggataaa tagttcctgg aacgatagta tcaaatccag cctctcgcaa
    20341 agtctgaacc aactcataac cataccgctc tttttgacca atcatatcca agacacaacc
    20401 ttcaagaaca ccttttaata gctgagtttc tttcatcact tctcccttct aatctatttt
    20461 gtaataccta ctagtaactt cacctatagt atatcacttc tacactagtt tgtaaagcat
    20521 aatagttaat actcttcgaa aatctcttca aaccacgtca gcgtcgccct accgtatgta
    20581 gggttactga cttcgtcagt ttcatctaca acctcaaaac t
//
LOCUS       DBJKQU010000036        20614 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.036, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000036 DBJKQU010000000
VERSION     DBJKQU010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.036"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            93..212
                     /locus_tag="ACSUUC_001461"
     CDS             93..212
                     /locus_tag="ACSUUC_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHQ8054654.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLI"
     gene            231..1415
                     /locus_tag="ACSUUC_001462"
     CDS             231..1415
                     /locus_tag="ACSUUC_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHQ8054655.1"
                     /translation="MLISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAY
                     RLSEGYGTDGPSAGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSL
                     FMAITIGLVTAEIYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGL
                     EAAGVAGGLNGLLGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDP
                     VWLQFTTENQEAVAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKT
                     LGKLAIIPSIFNINTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTG
                     VILPWTMPPIIGGFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVG
                     GK"
     gene            1417..3303
                     /locus_tag="ACSUUC_001463"
     CDS             1417..3303
                     /locus_tag="ACSUUC_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HHQ8054656.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            3471..3815
                     /locus_tag="ACSUUC_001464"
     CDS             3471..3815
                     /locus_tag="ACSUUC_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHQ8054657.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            3825..5237
                     /gene="lacG"
                     /locus_tag="ACSUUC_001465"
     CDS             3825..5237
                     /gene="lacG"
                     /locus_tag="ACSUUC_001465"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HHQ8054658.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            5307..6986
                     /locus_tag="ACSUUC_001466"
     CDS             5307..6986
                     /locus_tag="ACSUUC_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HHQ8054659.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(7112..8551)
                     /locus_tag="ACSUUC_001467"
     CDS             complement(7112..8551)
                     /locus_tag="ACSUUC_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HHQ8054660.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(8555..9904)
                     /gene="trkA"
                     /locus_tag="ACSUUC_001468"
     CDS             complement(8555..9904)
                     /gene="trkA"
                     /locus_tag="ACSUUC_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HHQ8054661.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            10093..10941
                     /locus_tag="ACSUUC_001469"
     CDS             10093..10941
                     /locus_tag="ACSUUC_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM hydrolase/SAM-dependent halogenase family
                     protein"
                     /protein_id="HHQ8054662.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10956..11504
                     /locus_tag="ACSUUC_001470"
     CDS             10956..11504
                     /locus_tag="ACSUUC_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HHQ8054663.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            11511..11723
                     /locus_tag="ACSUUC_001471"
     CDS             11511..11723
                     /locus_tag="ACSUUC_001471"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054664.1"
                     /translation="MKIKEQTRKQVAGCSKQCFEVVDETDEVSNHTYGKAKLTWFEEI
                     FEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            11825..13507
                     /locus_tag="ACSUUC_001472"
     CDS             11825..13507
                     /locus_tag="ACSUUC_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054665.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETPELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            13492..14322
                     /locus_tag="ACSUUC_001473"
     CDS             13492..14322
                     /locus_tag="ACSUUC_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T family protein"
                     /protein_id="HHQ8054666.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            14515..15018
                     /locus_tag="ACSUUC_001474"
     CDS             14515..15018
                     /locus_tag="ACSUUC_001474"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0141098 - tRNA
                     (cytidine(34)-2'-O)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HHQ8054667.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      15072..15306
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            15471..16034
                     /locus_tag="ACSUUC_001475"
     CDS             15471..16034
                     /locus_tag="ACSUUC_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHQ8054668.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            16024..16674
                     /locus_tag="ACSUUC_001476"
     CDS             16024..16674
                     /locus_tag="ACSUUC_001476"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HHQ8054669.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIR
                     GDLPDYLTILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            16702..17091
                     /locus_tag="ACSUUC_001477"
     CDS             16702..17091
                     /locus_tag="ACSUUC_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HHQ8054670.1"
                     /translation="MKVNIADLHLTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            17096..17545
                     /locus_tag="ACSUUC_001478"
     CDS             17096..17545
                     /locus_tag="ACSUUC_001478"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8054671.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKKIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            17673..18260
                     /gene="rpoE"
                     /locus_tag="ACSUUC_001479"
     CDS             17673..18260
                     /gene="rpoE"
                     /locus_tag="ACSUUC_001479"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HHQ8054672.1"
                     /translation="MKLEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVTPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            18650..20257
                     /locus_tag="ACSUUC_001480"
     CDS             18650..20257
                     /locus_tag="ACSUUC_001480"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HHQ8054673.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         6116 a         3542 c         4581 g         6375 t
ORIGIN      
        1 aaaatattgt aaaaacaaca aaaaatatat tgacaacgct ttctgttagt ggtatattta
       61 atttataaaa aataaaaaaa ggagttccgg tgatgaacaa tattttagcg tttttagaaa
      121 caaaagtcgc tccgtttggt gaaaaagttg gcaaccaacg gcatttgaaa gctattcgtg
      181 aaggatttat gatggcaatg cctttgattt gagtcggatc tttatttctt attctaatca
      241 gttggcctca agaggatttt acaaattggc tgaatagtgt tggattgcta agtatcttga
      301 caactatgaa tcagtcaaca gtagcgatta tctccttggt cgcttgtttc ggtattgcct
      361 acaggttgtc ggaaggatat ggtacagatg gtccgtcggc agggatcata gccttatcca
      421 gttttgtatt gatggcacct cgtttttcga gtatggttta tgataaaaat ggggagcagg
      481 tcaagcagtt atttggcggc gcaataccat tttctagcct gaatgcatct tctttgttta
      541 tggcgattac tattggattg gttacagcag agatttatcg tatgtttatc cagcgcggaa
      601 ttacgataaa aatgccaagt ggtgtcccag atgtggtaag taaatcattt tcagctcttt
      661 tacctggctt tactactttt gttttgtggg ctctggtctt aaaaggtctt gaagcggcag
      721 gagttgcagg aggtctcaac ggactcctag gtgcaattgt tggaacaccg cttaagttaa
      781 ttgcaggaac gcttccaggt atgattctat gtgttattgt aaactcattc ttttggttct
      841 gtggagttaa tgggggacaa gttttaaatg cttttgtaga tccagtttgg ttacaattta
      901 ctacagaaaa ccaagaagct gtggctgcag gacaaacact ccaacacatt attacattac
      961 cgtttaaaga tttatttgta tttattggtg gcggtggagc gactattggt cttgcgattt
     1021 gtctcttcct atttagtaag agtcgtgcga ataaaacatt aggtaagcta gctattatac
     1081 cgtctatttt taatatcaat acagctattc tatttacgtt tccaacagtt ttaaatccga
     1141 ttatgctgat tccgtttatt gctactccta caatcaatgc cttaattacc tatgtatcaa
     1201 tggctgtagg attagtaccc tacacaacag gtgtaatcct tccgtggaca atgccaccga
     1261 tcataggagg cttccttgcg acaggagcta gttggcgagg agctctatta caagttgttt
     1321 tgattttggt ttctgtagca atttattatc cattcttcaa aattgcagat aaacgcaatc
     1381 ttgaaaaaga aaaagctact gttggaggga aataagatgg ttatcagagt atttgatcag
     1441 cagaaaaata cttattctag ctttgcctta gaggaattaa gttactatat aaatcgggtc
     1501 tttaagactg acatagaact tgtcgaggag aaggaagcgg atatttttgt aggattagtc
     1561 aataaagagg atagaaaaga ccatgttctt atctcattag acaagggtaa ggggagaatt
     1621 gagtctaata caattgtagg tttacttatt ggaatttacc gaatgtttca tgaatttggg
     1681 gttgtgtata ctagaccagg gcgcggacat gactttgttc cagagttacg atttgaagat
     1741 tttttagata aagagctatc tatagatgaa acagccagtt actatcatag gggagtatgt
     1801 atagagggag cagattcatt tgaaaatata ctagatttca ttgattggct acctaagatt
     1861 gggatgaaca gttttttcat tcagtttgaa aatccctatt cttttttgaa acgttggtat
     1921 gaacatgagt ttaatccata cctaaataaa gaaaaattct caaatgaatt agtacaagaa
     1981 ttgagtgata ggttggataa agaattgcaa aaaagaggtc ttattcatca tcgtgttggt
     2041 catggatgga caggtgaggt tttaggttac tcttcaaaat ttggctggga atcaggtctt
     2101 agtatttcag aggagaagaa accctatgtc gctgaaataa acgggaaacg agaattattt
     2161 aatacggctc cgattttaac cagtctggat ttttcaaatc cagatgtggc ggataagatg
     2221 gtagaaatta tcaaggatta tgccaagaaa agacctgatg ttaactactt acatgtatgg
     2281 ttgtcggatg ctcgtaataa tatttgtgaa tgcgaaaact gtagacaaga attggtttcg
     2341 gatcagtata ttcgtattct caatcaattg gatagggctt taacgagtga gggattagat
     2401 acaaagattt gttttctgct ttaccatgag ttgttatggg cgcctcagaa agaaaaatta
     2461 gataatcctg aacgctttac catgatgttt gcaccgatta caagaacatt tgaaatgagt
     2521 tatgcagatg tagattttga caattccata cctacgccta aaccttatct gcgtaataaa
     2581 attatacttc cgaattctct tgaggaaaat ttatcttatc tttttgagtg gcaaaaaaca
     2641 tttaaaggag atagtttcgt atatgactat cctttagggc gtgctcatta tggcgattta
     2701 ggctatatga aaattagtca aaccatttac agagatgtat cttatctttc taacctacat
     2761 ttgaacggtt acatttcgtg tcaagaatta cgtgccggat tccctcataa ttttcctaat
     2821 tatgttatgg gggaaatgct ctggaagaag acaagaagtt atgaagaatt gattgaagaa
     2881 tacttttctg ctttgtatgg gtcaaattgg cagtctgttg ttgaatattt agaaaaatta
     2941 tccagttatt cctcatgtga ttattttaat gcaattggca gtcgtcaaaa tgatgtttta
     3001 gcgaatcatt attatatagc ttacaatcta gctgataatt ttttgccaat tattgaggaa
     3061 aatatttcta agttattaaa tagtcaaaag gatgaatgga aacagctcag ttatcatcgt
     3121 gaatatgttg ttaagatggc gaaggcttta tatcttcaag caaccggaaa aacaaggcaa
     3181 gctcaagatg aatggagaaa tgtgttgaat tatatccgtg ggcacgaatt gctatttcaa
     3241 tctaatttgg atgtttatcg tgtaattgaa gtagcaaaaa attacgctgg tttccactta
     3301 taaatcataa gtatagaaaa tgaaccaagg tattcagaga agattgatcc taaatattat
     3361 gaaatttaag gatttttaag atatttaggg tcgactttct atttatatcg tagcgaagtc
     3421 attttaataa tgatgtgtaa aagatggatc aagattgagg aggaagaaag atgaaatcaa
     3481 aagaagaaat aaatatgctt ggttttacaa ttgtcgctta cgcaggagat gcaaggtcag
     3541 atttgatgga tgctttggcg tttgcgagag atggatattt tgaacaggca agagaattgg
     3601 ttgagtctgc aaacgactca atagtgtctg cccatcgaga acagactaat ttattagcgg
     3661 aggaggcatc tggagataat tttgaagtga gttttatcat gattcatggt caagatacct
     3721 tgatgacaac gatgctattg tatgatcagg tcaagttttt tattgatgaa tatgaacgaa
     3781 ttcgaaagat tgaagaacat attggtttgc aatgaggatt agtcatggaa aatttacagg
     3841 ttaaagcctt accgaaggag tttttattag gagctgctac cgctgcttat caagtagagg
     3901 gtgcaactag ggtagatggc aaaggaacaa atatgtggga tgtttatttg caagaaaaca
     3961 gtccgttctt accagatcca gctagtgatt tttattatcg ttacgaagag gatataactt
     4021 tggcggcaga acatggtttg caggctttgc gtttatctat ttcttgggtt cgtatatttc
     4081 ctgatataga tggggagcct aatatattag ctgttcgtta ttaccataga gtctttcagt
     4141 cttgcttaaa acataatgtg attccgtttg tttctttaca tcattttgat tcgcctcaga
     4201 aaatgttaga aacaggggat tggttgaata gagagaatat tgatcgtttc atacgatatg
     4261 ctcgcttttg tttccaagaa tttacagaag tcaagcattg gtttacaatc aatgaactga
     4321 tgtctcttgc tgcaggtcaa tatataggag gtcagtttcc tccaaatcat cattttcaat
     4381 tatctgaagc aattcaagcg aatcataata tgttgttggc gcatgctctt gcagtcctcg
     4441 aatttcatca attaggaatt gagggagaga taggttgtat tcatgcttta aagccaggct
     4501 atcctattga tgggcaaaaa gaaaatattt tggcagctaa acggtatgat gtttataata
     4561 ataaatttct attagatgga acttttttgg gctactacag tgaggacacg ctttttcact
     4621 tgaatcaaat attggaagct aataattcta gctttattat tgaagatggt gatttagaaa
     4681 ttatgaagag agctgcagct cttaatacga tgtttgggat gaattattat cgttcagaat
     4741 ttattcgtga atacaaaggt gaaaatagac aagaatttaa ttcaacagga ataaaaggac
     4801 agtcttcttt taaattaaat gctctaggtg aatttgtaaa aaaacctggt attccgacaa
     4861 cagattggga ttggaatatt tatcctcaag ggttatttga tatgttgctt cgtatcaaag
     4921 aagaatatcc tcaacatccg gtcatttatt taactgaaaa tggtacagcc cttaaagaag
     4981 ttaagccaga gggcgagaat gatattattg atgacagtaa gagaatccgt tatattgagc
     5041 aacatttaca caaagtttta gaggctcgag atagaggagt caatattcaa ggctatttta
     5101 tatggtcttt gcaagatcaa ttttcttggg cgaatggcta caataagcga tatggtcttt
     5161 tctttgttga ttatgaaaca cagaagagat atattaagaa aagtgctctt tgggtaaaag
     5221 ggctaaaacg gaattaaggt tagcgatttg actgatgttt aatatatttt aactatgagc
     5281 ttaaattttt tacaggagga gtttttatgg ataagttagt cgctgccatt gaaaagcaac
     5341 aagggaaatt tgaaaaaatt tctactaata attatatgat agctattaaa gatggattta
     5401 ttgctactat gcctttaatt atgttttcaa gctttttgat gattattatt atgattccta
     5461 aaaatttcgg agtagagtta ccgagtccag ctattgcctg gatgaggaaa gtgtatatgc
     5521 taaccatggg agttttgggt attattgttt cagggacagt tgcaaagtca ttggctggaa
     5581 atgttaatag aaaaatgcct cctggaaagg taataaatga tacttctgca atgttggcgg
     5641 ccatatgtgg ctatcttgta ttaactgtaa cgcttgtagt tgatgagaaa acgggatcta
     5701 caagtttgtc gacaaactat ttaggatctc aaggattgat aacttcgttt gtcagtgcct
     5761 ttattactgt aaatgtttac cgattctgta ttaagcgaga cattactatt catttaccta
     5821 aggaagttcc tggggctata tcacaagctt ttagagatat ttttcctttt tcttttgttt
     5881 tacttattag tggtttgtta gatattgtat ctcggtttag tttagatgtt ccttttgccc
     5941 aagtatttca acaactattg actcctattt ttaagggggc agaatcatat cctgctatga
     6001 tgttgatttg gtttatgtgt gctttgcttt ggtttgttgg aattcatgga ccatctattg
     6061 tcttacctgc tgttacagct ttacaactga gcaatatgga agagaatgct caacttcttg
     6121 caaatgggca gttcccttat cattctttaa cacctaattt cgggaattat atcgctgcta
     6181 ttggaggaac gggggctacc tttgttgtac catttatttt gattttcttt atgcggtcta
     6241 aacaattaaa atcggtaggt aaagctacaa ttactcctgt tttatttgcg gtaaatgaac
     6301 ctcttctatt tggtatgcct gttattttga atccctatct ttttgtccct tttttgatga
     6361 ctccaccagt gaatgtattt ctaggaaagg tatttattga tttctttgga atgaatggat
     6421 tttatatcca gttaccttgg gcctttcctg gtcccttggg attgttaatt ggaacgaatt
     6481 ttcaacttat ctcctttgta tttttatctt tgatgttagt tgtcgacata ttgatttatt
     6541 tgccattctg tagagcgtat gatagacagt tactggtgaa agaagatatt gcaagctcaa
     6601 atgatattat tttagaggag gatacaagtg aaataatgcc tggtgagata gatgtaataa
     6661 aaagtaagga gttgaaagta ctggttcttt gtgcagggtc tggaacaagt gcgcaattag
     6721 ccaatgcaat taacgagggc gctcaattag cagaagttag agtgattgcg aattcaggag
     6781 cgtacggagc tcattatgat attatgggtg tttatgattt aattattctg gccccacaag
     6841 ttcggagtta ttatagagag atgaaggtgg atgcagaaag attagatatt cagatagttg
     6901 ctaccagagg aatggaatat attcatttaa caaagagtcc aagtaaagcc ttacaatttg
     6961 tattggagca ttaccaagct gtgtagtaag tttttccatc ttttatttga gtaaagattt
     7021 tgcttacaga taggcttgga tttaaaaacg ttcccccttt tttaatataa gaatccctct
     7081 ttcacaattg taaaaagagg gattttgtat tttatctctt agaccaagtt ctcttcataa
     7141 agagaaggag gattgggtaa atctccaagc gccctgcaat cattgcaaag gataggagaa
     7201 tttttgagat gggactaaag attgagaaac tagaagtggt tcctagaata ggcccgatat
     7261 tattgaaaca gctaaagaca gcgctggtca cgaccagaaa atcattgcta tctaggctga
     7321 caataaagat aagcgctagc aaaatcatag catagatgac aaagtacttg agaatcttat
     7381 gctgggtatc tttgtcaatc accgttttat taacatggag ggtcaaaaca cggtggggcg
     7441 ataggattga caaaatttgg tttttggcaa tttttgaaag gatgaggcct cgaataatct
     7501 tgagtccacc tgcagttgat ccagcagagc caccgattgc catgaggaaa aggaggataa
     7561 actgggagaa gaggggccag ttggtaatat ctccatatcc aaaaccagtt gttgtaatga
     7621 tgttggaaac ctggaagaag gtcatttcaa agctctttga aaaccctggg tagaggtaga
     7681 gggtgttgag gctaatcaag cctgtagaaa ccagtacaat gaccaagtaa gccctaagct
     7741 cttcatctcc aaagaaggcc ttgatgcgac ggagcatgag gtagtagtag aggttgaaat
     7801 ttactccaaa aaccagaact ccgatactga ccagataggt aatcagtgag ctgccatagt
     7861 gggcaattcc gtcgttatag acggtaaagc ctccagttcc cgctgtcccc atagcaataa
     7921 caaaactatc gtagagaggc ataccggcta gataatagat gatgacaaag agggagaaga
     7981 gagctagata aaggagatag agaatctggg cagtgttttt tagtttggat acaaccttgc
     8041 caaaaacagg acctggaacc tcagccttca tcacctctag gtggctattt ttggcattgt
     8101 ccataatagc aagtgcaaaa acaagcactc ccatccctcc aatcaagtgg gtaaaacttc
     8161 gccagaagag gagggaacgg ctgagaaccg aaacgtcgtt caaaatactt gctccagtag
     8221 ttgtaaatcc agaactaatt tcaaaaaagg catcaataag gctggggatt tgcccagaaa
     8281 agacaaaggg gagaccacca aagaaagacc aaaggatcca acagagggca acgatcaaga
     8341 ctccctcctt ggcataaatc cgttgatttt ttggcttctg taaactccct gaaccgccta
     8401 acaatacgag aatccctatg gtcgaaaaga gggctgtaaa gacttggctc gattcacggt
     8461 aatagacagc aatcgcaaca ggaaccaaaa gaagaacagc ttcaatcaaa agtaattttg
     8521 aaaggaggta acgaatcata cttttattca tttcttacct cgcgatcaag tcataaatct
     8581 tggtgatgtt tggcaacaag gttgttacta ggagcttgtc tccaacttcc aacatatcct
     8641 ccccagttgg gaaaatagtc ttgccctttc gaataatggc tgcaataaga accccttttt
     8701 ttaatttcag ttgagaaaga ggtttggcag tcattttatt ggcttccttg atatggaatt
     8761 gcagggtttc gatttggcca ttggctagat ggtgcatggc ttgaaggtct gaatactggg
     8821 cattaactcg accacgaata aagtgcataa tcgtatctac agcgatgctt ttaggtgtga
     8881 tgatacttga aaaatcaggc gcattgataa tctcgaggag actggtacga ttgaccttag
     8941 taatattttt ctgtacacct accctgtcaa ggaacataga tgtaatcaga ttttcctcat
     9001 cgacacctgt tagagtcgca acggcatcat agtgttgagc actttcttcc agcaggatat
     9061 cttttgcggt tccatctcct tgaacgatgt agagatttgg gaatttctcg ctaaagaagc
     9121 tggcgatttc aggattgatt tcaatgactt ttgtatcgat acgactatct ttgagaatac
     9181 caagtagata ataggcaatt ctacctgccc caacgatgag aaggctcttc acggcgcgtg
     9241 atttaaaata attatggaag agtatcatat cgacacggtt accagtgaca aagattctat
     9301 ctttatcctg tacagtcatg tcaccgcttg gaatgataat ttgatgatcc ctctctatcg
     9361 cacagacaat gacattacca aattttttac gaaaatcaga aatgggcatt tggcaaagac
     9421 cgctggtgga cttgacgaca aattccatga ggctaacgcg tccaccagca aagcgttcga
     9481 cagacagggc gttggggaag tcaatgatat tcgcgatagc gcgggcagcc aagagctcag
     9541 gattaacgat aagagaaaaa ccgagaatat tcttttcctt gaaataagag ttagaatatt
     9601 cagggttccg cacccgaacg atagtttctt tagctcccat tttcttggct agaactgctg
     9661 caatcatgtt gacttcatcg tgctcagtca gggcgataaa gatatcacaa tcttggacgc
     9721 tggcttgctc aagaatggca aaatcggccc cgttaccaag gataccaatg atatcaaagc
     9781 gactgacaat atgattgaga acagcttcgt cttgctcaat cagcaaaaca tcatgctttt
     9841 ctgcaaccaa ggagcgacag agggcaaaac caacttttcc ccctccgaca aggataattt
     9901 tcataataaa acctactttt tcatgatgta actatcatac cctttttcaa gaaaaaatgc
     9961 acctactagc taataaccag agtttttagt aggaaatttg ctataagtta aaactatacc
    10021 ctaaccaatt gaaatagcta ttagcgactt tctctgaaat atggtatgat aaaggatata
    10081 caaggagata aaatgaataa taatttactg gtattacaat cagactttgg tctggttgat
    10141 ggtgcggtat cggctatgat tggagtggct ttagaagagt ctccaacctt aaaaatccat
    10201 cacttgacgc acgatatcac gccttataat atttttgagg ggagctatcg tctctttcag
    10261 acggtggatt actggcctga gggaacgacg tttgtatcgg ttgtcgatcc aggtgtcggt
    10321 tcgaaacgta agagtgtagt tgccaagact gcaaaaaatc aatacattgt cacgccagat
    10381 aatgggacgc tttcctttat caagaaacac gttggcattg tagccattcg tgagatttct
    10441 gaggtggcca ataggcgtca aaacacagag cattcttata ccttccacgg tcgtgatgtc
    10501 tatgcctata ctggtgctaa actggccagt ggtcacatta cttttgagga agtagggcca
    10561 gagctcagtg tggaacagat tgtagagctt ccagtcgtag cgaccatcat agaagatcat
    10621 ctggtgaagg gagccattga tattctggat gtgcgtttcg gttcgctttg gacctctatc
    10681 acacgggaag aattttacaa gttggaacca gaatttggtg atcgttttga agtgaccatc
    10741 tatcatgctg atatgctggt ctatcaaaat caggttgtct atggcaaatc atttgcagat
    10801 gtgagaattg ggcaacccat tctttacatc aactctctct atcgtttagg tttggctatc
    10861 aaccaaggtt cctttgccaa ggcctataat gtaggtgtcg gttcatcttg gaccattgaa
    10921 ataaagaaaa tagaaggata aaataggaga atagtatgga aatcaaattt acaattaaac
    10981 aagttgttgc tgtcggaatt ggcgctgccc tctttgtcgt catcgggatg atcaacattc
    11041 caacccctgt tccaaataca agcatccagc ttcagtatgc ggtacaagcg ctactttcta
    11101 ttatttttgg accgattatc ggtttgcttg ttgggttgat tggtcatgca atcaaggact
    11161 ctcttgttgg ttatggtcta tggtggactt ggattatcgc tagcggactc tttggtttag
    11221 ttgtgggact ttttagaaag tacgttcgcg tgatcaatgg tgtttttgac tggaaagata
    11281 ttcttatttt taacctcatt caactacttg caaatgccct tgtttggggt gtcttggcac
    11341 cacttggaga tgttgtgatt tatcaagaag cggcagaaaa agtatttgca caaggaattg
    11401 ttgcgggaat tgccaatggt gtatctgtag ctattgcagg aactcttctc ttacttgcct
    11461 atgcaggaac tcaaactcgt gcaggaagtt tgaaaaagga ctaatactca atgaaaatca
    11521 aagagcaaac taggaagcaa gtcgcaggtt gctcaaaaca gtgttttgag gttgtagatg
    11581 aaactgacga agtcagtaac catacctacg gcaaggcgaa gctgacgtgg tttgaagaga
    11641 ttttcgaaga gtataaaatg atggggaagg ctgggcaact agtctttttc gatgtttata
    11701 gattagttag gcaagtaagc taggatagga atctttttgg cgctaagatt ttaagagaag
    11761 agactgcaag aagggcttga tttatgataa aatagaagtc taagaagcga atgaagagag
    11821 taagatgaaa gaagctataa ttgagtggaa ggatttctct ttccggtatg aaacacaaca
    11881 agaaccgacc ttgcaaggga tagacttgac catttacaag ggagagaaag tcttaattgt
    11941 tggaccatct ggatcaggta aatctacctt gggtcagtgt ttgaatggga ttattcccaa
    12001 tatttacaag ggtcagacat atggagaatt tttgataaag ggtcaaacag cctttgatat
    12061 gagcatctat gataagtctc atctggttag cacagttttg caggatacag atgggcagtt
    12121 tattggcttg tctgtggcag aagatttggc gtttgctctg gaaaatgatg tgacagccct
    12181 agatgagatg aaaggtcgtg tttataaatg ggctgaaaag ctggaccttc ttcctttact
    12241 ggatcagcgc cctcaggatt tgtcaggtgg acaaaagcag cgagtcagtc tggctggtgt
    12301 cttgattgat gaaagtccga ttctcttgtt tgatgagcca ctcgccaatc tagatcccaa
    12361 gtcaggtcag gatattatcg aattgattga ccagattcat aaggaagagg ggacgacgac
    12421 tctgattatc gagcaccgtt tggaggacgt tctgcatcgc cctgtggatc ggattgtctt
    12481 gataaacgat ggtcgtatcc tttttaatgg gagccctgac cagttgcttg cgactgattt
    12541 attgactcaa aatggaattc gagaacccct ttatctaacg actctccgtc aattaggtgt
    12601 ggacttagtc aaggaagaac aattagcaga tctggataac ttgtctatct caaaagggca
    12661 agtccagtta cagacggaac tggtaaaaga aaccccagaa ttgcagtcac tctttagact
    12721 agaggaagta tctttttctt atgatgatag accgatttta aaatccctac atttagatat
    12781 taaaaagggt gaaaagattg ctattgtcgg aaaaaatgga gcagggaaat caactctagc
    12841 caaggctata agtagcttta ttcagacgga aggacgctat ctttgggaaa aacaggatat
    12901 aaaaggcgat tctgttgcag agcgggcgga acgagtaggc tatgtgctac aaaatcctaa
    12961 tcaaatgatt tcaaccaata tgatttttga tgaggtggct ctagggctcc gtttgcgagg
    13021 tgtggatgag aaggaaattg aaacgagagt ctatgaaacc ttgaaaatct gtggacttta
    13081 tgaattccgt aattggccta tttctgccct gtcatttggt cagaaaaaac gtgtcaccat
    13141 tgcttcaatt ttggtcttag gagctgaaat tattctccta gatgaaccga ctgcaggtca
    13201 agatcagaag aactatactg agattatgga atttctcgaa gagttacatc aaaaagggca
    13261 taccattgtc atgattaccc atgatatgca attgatgctg gattattcag accgggtcct
    13321 tgtcatggtg gatggagaat tgattgccga tactgttcca gccagtctgt tgagcgatcc
    13381 tgagctgtta gtaaaagcca atctaaaaga aacctccatc tttaacttgg ctaagaaact
    13441 agatgtggat ccactggatt taacggcatt ttacaaagaa aggagagagg gatgcaagct
    13501 aaattaatcg gttaccagca tagagatact gtgattcatc gcttgtcagg agctgggaaa
    13561 cttctctttt tcattctggt atcattggcg gccatgatta gctatgatac cagaatgctc
    13621 ttgctgattg ccatcttttc agtctttctc ctctatttat cagaaattcg ctttaaagat
    13681 gtttcctttg tagccgtttt tgcgacggta tttgccgttt taaacgtttt gatggtctat
    13741 ctcttttctc ccgagtatgg ggttggactt tatggagaga gaagtgtgat ttggcaggga
    13801 atcggtgtct acactctaac cagccaggag ctcttttatc tgctaaattt ggccattaag
    13861 tatctttgca ccattcctct ggctattatc tttttgatga caacccatcc tagtcagttt
    13921 gcttccagtt taaatcaaat tggtgtgccc tataagattg cttattctgt cagcctgacc
    13981 ttgcgctata ttccagattt gcaggaagaa ttctttacta tcaagatgtc tcaggaggcg
    14041 cgtgggatgg aattatccaa gaaagcttct cttatgcaac gaatcaaagg caatctgctc
    14101 attattacgc ccttgatttt tagctcgcta gaacgcattg ataccattgc gactgccatg
    14161 gagcttcgcc gctttgggaa agagaaaaaa cgcacatggt atagttatca ggccttgaaa
    14221 aaaggagact atattacctt gctcttggca accttgtttt tagtagttag tttactactt
    14281 atcttgcaga atcagggacg attttacaac ccttggaaat agcttgaaaa aattgaaaaa
    14341 atcaagtcgt ttctattgac aatgattctg aaagtgttat actaagaaag tagtttcgct
    14401 gatttacttc aaacctgttg tgaggtaagt taacgatgcc ttaaccacgc tgtttgctga
    14461 gcttgactcc gggcagtgtg gctatttttt tgcaatggtg aaaggaagca agtcatgaca
    14521 aatcacattg tattatttga acctcaaatt ccacaaaata cgggcaatat cgcgcgtact
    14581 tgcgctgcga ccaattctcc cctccacatc atcaagccta tgggctttcc tattgatgac
    14641 cgcaagatga agcgggctgg attggattac tgggataagc tagagattta tttttacgag
    14701 agtttggaag atttcatatc tcagatgaag ggaaaactct atctgatttc gaaattcgcg
    14761 gaaaaagtct attctgaggt ggatttatcg actgacgagg accattattt tctctttgga
    14821 cgtgaagaca agggcttacc tgaagatttt atgcgagaac atcctgagaa ggctctccgt
    14881 attcccatga atgatgaaca tgtccgcagt ctcaatgtgt ctaataccgt ctgcatgatt
    14941 gtctatgagg ctcttcgcca gcagaacttt gcaggtcttg agctcgtcca tacctatgaa
    15001 gtggataaat tgaaataaaa aatgaaaatg aacaaaatgc ttgcgcttgc aagcgttttt
    15061 tgttatgata aaagagtctt cagggcaggg tgtgattccc gaccggcggt gactttaact
    15121 aggaaatgat cttttccttt tatactttgt tgacaagctt tgcctaacca gaagttatgc
    15181 ctacagcttg tcgcctagtc taaaagaaaa atctctattt ccttctcttt aaagaagtcc
    15241 gcgagcgcaa gctgatgtgg tgagattcca caaccgacag tatagtctgg atgggagaag
    15301 acgaaagaat agctttgtct gttttgatag atttatagcc ggattgtaac cacttgcttt
    15361 gtttttcttt aatagagtaa gagggaactt ttgggatata aaaagtgaga atagatagag
    15421 gaatcctttc caacttcttc tgattttata gaaaattgga ggaacctgtt atgacaaata
    15481 cacgtcgact ttcgaccatt gcaattttat cagccatctc atttgtgctg atgtactttg
    15541 actttccgct tttaccagcg gcatctttcc tcaagatcga atttagtatc ttgccagtcc
    15601 ttgtgggtct ggtggtcatg gatttgcctg ctgctctagg agtgctcttg cttcgctcac
    15661 tcttgaaatt gcttcttaac agccaaggag tgaatactta cattggtttg ccgatgaata
    15721 tcgtagcttt gggagttttt gtcatcgtat ttgctttgat ttggaaaaag gaacggacaa
    15781 cccttcgttt cctactaggc tctctagctg gaactgttgg tttaaccttg gccatgttgg
    15841 ttctcaacta tgtttatgct gttcctttgt acgctaagtt tgctaacttt gatattggaa
    15901 aaattttggg actttccaac tacctaatga ccatggtatt accttttaac ttgattgagg
    15961 gtgtaatctt ttccgtttca ttctggttgt tgtacgtcct tttgaaacca accttaaaac
    16021 actatgaaag ataaacaaac atttttaatg aagggcagtt ttgccctttt acttttcgtt
    16081 attcttggct atatggtcaa attttaccct gaaatgttgg tcaattttga ccaatcgatt
    16141 cagactgcca ttcgaggaga cttaccagat tatttgacta ttctttttcg agccctcaca
    16201 cgtctgattg atatcccagt gattatcact tgggttgtca ttacagcttt tgtcttttat
    16261 cgtaagcgat ggaagataga aagtttcttc atgctgggaa atctggcttt ggcaggtctt
    16321 ttaatcgtga cctttaaaaa tatctaccag cgcccacgac cagctatctt acatctggtg
    16381 gaagagaagg gattttcctt cccaagtggg cattctctgg ctgtaacttt gatggtaggt
    16441 actctgattg tcattctcag tcaacgaatt aaaaatccag tctggagaaa aatcgtacaa
    16501 atcgtccttg gcctctacct agtcagtgtg ctggtatcaa gagtctatct gggagttcat
    16561 tacccatcag acgtccttgc cagtctctgt gtgggcttgg gagtcctgtt tatcgagttt
    16621 cccttctatg acaagctccg cttccaatgg cgatttaaag gcaaacagaa gtgagtatcg
    16681 aattcccttg aggagaaaga aatgaaagtc aatatagcag atcttcatct gactcaacta
    16741 tatttatcag aaaagaagtt gcaagatatt cagatgcttt accagtcggc agaaacaatc
    16801 caagtcgatc caatcagtat tcttgccttt ggagattgtt tgctgattac agatgggcat
    16861 cacagggctt atcaggcttt attggcaggt cgggatacga tttctgctga gtgggataga
    16921 gatggtggtg atgaactata tcatctctat gcgcaagctt gcgaggaaag aaagatttac
    16981 tctgtttttg atttagaaga tcgtatccta gctcaagatg ggtatgaagc aaaatggtat
    17041 aactggtgtg atggttttaa tcaagcagca actcttttgt tgaaaaggta gtgcattgtg
    17101 ttttgttcct tattataagg tcaatcattg tgaggaagct tttgcttggt atcaggatgt
    17161 gaacttggtt tacctcgtag atggggtgaa gcttccttac agtcaagcga ccttggaagc
    17221 catgtattcc tatttggatc ggcatggtga gcttttttgg attgaagtca aggagaaggg
    17281 agaatggttt ccaattgggg atattacact atctcaggat aatctcccca ttgtgattgg
    17341 gaattccgct taccaacatc gaggacttgg aaaaaagatt ctaagtgctt tgattgaatt
    17401 ggctcgagta aaaggatgga aagaattgag agtcaagaaa atctacacct acaatcatgc
    17461 ttctaggagg tgtttcaagt cgcttggatt tgtggaaaat ggagcaacag aaaaaggaat
    17521 gagttttata ttggaattag tctaatcctg ccactttctc ccccttaacc tttgactatt
    17581 ccgcaaaatt atcgtaaaat aaagagtgaa tgataaaatg aggtcagagt ctgttcgctc
    17641 tggcgatagt agtataaatg aggagaaacg ctttgaaatt agaagtattt gctgggcaag
    17701 aaaaaagtga actatctatg attgaggtag cgcgtgctat cttggaactt cgtggtcgcg
    17761 atcatgagat gcattttagc gatcttgtaa acgaaattca aaactacctt ggaacatcaa
    17821 acagcgatat ccgcgaagct ttgcctttgt tctacacaga gttgaacttt gacggtagct
    17881 tcatctcact tggggacaac aaatggggtc ttcgttcatg gtatggtgtg gacgaaatcg
    17941 acgaagaaat catcgctctt gaagaaaatg acgacgatga agtaacacca aaagctaaga
    18001 aaaaacgtgt caatgccttt atggatggtg attcagatgc cattgactac aatgcagatg
    18061 atccagaaga cgaagatgca tacgaagcag atccagctct ttcatacgat gatgaaaatc
    18121 cagatgatga aaaaaatgaa gtggaagctt atgatgcaga aatcaacgaa atcgctccag
    18181 atgacttggg agaagatgtg gatctcaacg aagacgacga cgagttttca gacgacgacg
    18241 ctgaaaccag cgaggaataa gagttagcta ttgacaatta tcctattttt aggtatcata
    18301 ttgtttgggc acctctttta gaggtcgggg ctccctagtt cttagggagc tatttttgtt
    18361 ttttcaagaa gttatcttct tgtattttat actcaatgaa aatcaaagag caagctagga
    18421 aactagccgt aggctgctca aaacactgtt ttgaggttgt agataagact gacaaagtca
    18481 ggaacacata tctacggcaa ggcgacgttg acgcggtttg aagagatttt cgaagagtat
    18541 tagttgtgaa tctggtgcag tcgtcccaga ttattcttat tagtagggtc ttgttttcta
    18601 tatcccctcg tagttaacaa gaccttgagc attttagaaa gaggaatcta tgtctacgaa
    18661 atatattttt gtaactggtg gtgtggtatc gtccattggg aaagggattg tggcagcgag
    18721 tctaggccgt ctcttgaaaa atcgtggtct caaagtaacc attcaaaagt ttgaccctta
    18781 tatcaatatt gatccgggaa ccatgagtcc ttaccagcac ggggaagttt ttgtgacaga
    18841 tgacggagct gagacagatt tggacttggg tcactatgaa cgtttcatcg atatcaatct
    18901 caacaaatat tccaacgtga caactgggaa aatttacagt gaagttcttc gtaaagaacg
    18961 ccgtggagaa taccttgggg caactgttca agtcattcct catatcacag atgctttgaa
    19021 agaaaaaatc aagcgtgccg ctctaacgac cgactctgat gtcattatca cagaggttgg
    19081 tggaacagta ggagatatcg agtccttgcc attcctagag gctcttcgtc agatgaaggc
    19141 agatgtgggt gcggataatg tcatgtatat ccatacaacc ttgcttcctt acctcaaggc
    19201 tgctggtgaa atgaaaacca aaccaaccca acactctgtc aaagaattgc gtggcttggg
    19261 aatccaacca aatatgttgg ttattcgtac agaagagcca gctggtcaag gaattaaaaa
    19321 taaactggcc cagttctgtg atgtggcacc agaagccgtt atcgaatcgt tggatgttga
    19381 acacctttac caaattccac tgaacttgca ggcacaaggg atggaccaaa ttgtttgtga
    19441 tcatttgaaa ttagacgcac cagcagcgga tatgacagaa tggtcagcca tggtggacaa
    19501 ggtcatgaac ctcaagaaac aagttaagat ttcccttgtt ggtaagtatg tggagttgca
    19561 agatgcctat atctcagtgg tcgaagcctt gaaacactct ggctatgtca atgatgtaga
    19621 agtcaaaatc aattgggtca atgccaatga tgtgacagca gagaatgtag cagaactctt
    19681 gtctgatgcg gacgggatca tcgtaccagg tggttttggt caacgtggta cagaagggaa
    19741 aatccaagcc atccgctatg cgcgtgaaaa tgatgttcca atgttgggag tctgcttggg
    19801 aatgcagttg acatgtatcg agtttgctcg tcacgtttta ggtcttgaag gtgccaattc
    19861 tgcagagctt gcaccagaaa caaaataccc tatcattgat atcatgcgtg atcagattga
    19921 tattgaggat atgggtggaa cccttcgttt gggactttat ccgtctaagt tgaaacgtgg
    19981 ctctaaggct gctgctgctt atcacaatca agaagtggtg caacgccgtc accgtcaccg
    20041 ttatgagttt aataatgcct tccgtgagca gtttgaggca gcaggttttg tcttttcagg
    20101 agtttctcca gacaatcgtt tggtagaaat cgtggaaatt cctgaaaata aattctttgt
    20161 agcttgtcag tatcaccctg aactgtcaag ccgtccaaac cgaccagaag aactctacac
    20221 tgcctttgtt actgcagcgg ttgagaacag caattagcaa aatcagaacc tttgagaaaa
    20281 atctcagagg ttttttgcat acgatgatat tgcagtatat ctgaggtagg ggtcctctgt
    20341 atgtacctgc taccgttgaa atcaatagcg actccctctt gccctgtgct agtgaatgga
    20401 tttatcagta tattgaaatg aaataaaatt tgaacaaatt aattcggaaa gccaaatcaa
    20461 tttctagcaa agttttagga actggattgt atagtgaatt gaaataagat gtgaacatct
    20521 ctatcagaaa agtcaaatta atttatagaa atattttagc agtcaagatg tactgttata
    20581 gattcaatac attatacttt tttaatttaa tcca
//
LOCUS       DBJKQU010000037        20341 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.037, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000037 DBJKQU010000000
VERSION     DBJKQU010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.037"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(112..387)
                     /locus_tag="ACSUUC_001481"
     CDS             complement(112..387)
                     /locus_tag="ACSUUC_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HHQ8054674.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(493..1332)
                     /locus_tag="ACSUUC_001482"
     CDS             complement(493..1332)
                     /locus_tag="ACSUUC_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HHQ8054675.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1474..2322
                     /locus_tag="ACSUUC_001483"
     CDS             1474..2322
                     /locus_tag="ACSUUC_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHQ8054676.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2415..3332)
                     /locus_tag="ACSUUC_001484"
     CDS             complement(2415..3332)
                     /locus_tag="ACSUUC_001484"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HHQ8054677.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWY"
     gene            3800..3958
                     /locus_tag="ACSUUC_001485"
                     /pseudo
     CDS             3800..3958
                     /locus_tag="ACSUUC_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family putative permease subunit"
     gene            complement(4284..4577)
                     /gene="rpmA"
                     /locus_tag="ACSUUC_001486"
     CDS             complement(4284..4577)
                     /gene="rpmA"
                     /locus_tag="ACSUUC_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HHQ8054678.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4594..4938)
                     /locus_tag="ACSUUC_001487"
     CDS             complement(4594..4938)
                     /locus_tag="ACSUUC_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HHQ8054679.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4954..5268)
                     /gene="rplU"
                     /locus_tag="ACSUUC_001488"
     CDS             complement(4954..5268)
                     /gene="rplU"
                     /locus_tag="ACSUUC_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HHQ8054680.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5305..5392)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5487..6086)
                     /locus_tag="ACSUUC_001489"
     CDS             complement(5487..6086)
                     /locus_tag="ACSUUC_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HHQ8054681.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDIR
                     DKLLTLIAFMMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIGFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGVVFSVYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6557..6799
                     /locus_tag="ACSUUC_001490"
     CDS             6557..6799
                     /locus_tag="ACSUUC_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HHQ8054682.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALE"
     gene            7076..8089
                     /locus_tag="ACSUUC_001491"
                     /pseudo
     CDS             7076..8089
                     /locus_tag="ACSUUC_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8405..9379)
                     /gene="pta"
                     /locus_tag="ACSUUC_001492"
     CDS             complement(8405..9379)
                     /gene="pta"
                     /locus_tag="ACSUUC_001492"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - pyruvate decarboxylation to
                     acetyl-CoA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HHQ8054683.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(9423..10319)
                     /locus_tag="ACSUUC_001493"
     CDS             complement(9423..10319)
                     /locus_tag="ACSUUC_001493"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HHQ8054684.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSYIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(10316..11134)
                     /locus_tag="ACSUUC_001494"
     CDS             complement(10316..11134)
                     /locus_tag="ACSUUC_001494"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HHQ8054685.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(11118..11789)
                     /locus_tag="ACSUUC_001495"
     CDS             complement(11118..11789)
                     /locus_tag="ACSUUC_001495"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HHQ8054686.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRSITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            11917..12486
                     /locus_tag="ACSUUC_001496"
     CDS             11917..12486
                     /locus_tag="ACSUUC_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HHQ8054687.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTLDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            12599..13558
                     /locus_tag="ACSUUC_001497"
     CDS             12599..13558
                     /locus_tag="ACSUUC_001497"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HHQ8054688.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            13568..14683
                     /locus_tag="ACSUUC_001498"
     CDS             13568..14683
                     /locus_tag="ACSUUC_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HHQ8054689.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMH
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            14688..15035
                     /locus_tag="ACSUUC_001499"
     CDS             14688..15035
                     /locus_tag="ACSUUC_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HHQ8054690.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            15043..15258
                     /locus_tag="ACSUUC_001500"
     CDS             15043..15258
                     /locus_tag="ACSUUC_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HHQ8054691.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            15341..15982
                     /locus_tag="ACSUUC_001501"
     CDS             15341..15982
                     /locus_tag="ACSUUC_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HHQ8054692.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            16000..16689
                     /locus_tag="ACSUUC_001502"
     CDS             16000..16689
                     /locus_tag="ACSUUC_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HHQ8054693.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGKPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(16686..17366)
                     /gene="radC"
                     /locus_tag="ACSUUC_001503"
     CDS             complement(16686..17366)
                     /gene="radC"
                     /locus_tag="ACSUUC_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HHQ8054694.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHLSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(17409..19700)
                     /gene="pcrA"
                     /locus_tag="ACSUUC_001504"
     CDS             complement(17409..19700)
                     /gene="pcrA"
                     /locus_tag="ACSUUC_001504"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HHQ8054695.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLNITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSVLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(19892..>20341)
                     /locus_tag="ACSUUC_001505"
     CDS             complement(19892..>20341)
                     /locus_tag="ACSUUC_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HHQ8054696.1"
                     /translation="KSIALKKELANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNYSH
                     DMKLFKMSCRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKACNHALS
                     KERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
BASE COUNT         6270 a         4278 c         3665 g         6128 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagccg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaattgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt ttttaggagt ggtaacgtat caaaatagcc caagcgttct cacccgtgtg
      541 agtttgaata atggaacccg tttccaaaac agaaattggc ttttcaacat aagcttgtaa
      601 gctttctttc atctcttttg cccaatcatc actaccagaa tatgaaattc caatctctgc
      661 tacagcacgt tcagaaagcg atgttatcaa ctcatctaac cattttttaa atgttttagt
      721 tccacgacct ttaaccattg gctgcaattc atggtctttc atttgcatga caacacggat
      781 attgagaagg gagctcaaca agccagttac acggccaatt cgtccacctt tgacaagatt
      841 ttccaaagtt gaaacaccaa tataaagctc tgtatggttt ttaacctctt ctacatgaga
      901 taaaattgcc tccatatctt taccttcttg agctaacttc gcagcctcaa caacttggaa
      961 tttcagggct tggtcagtga aggaactatc aacaacagtc acatctgcag tagataggct
     1021 agcaccttgg cgtgctgctt ctaccgtacc cgaaagagca tgggacatat gaatagcaag
     1081 aatctggcca ccatctttgc ataggtcttc aaaaatctca gcaaagacac ctacaggtgg
     1141 ctgacttgtt ttcggaagat tcttactttc ttgcatcaac tgaagaaatt taccttcttc
     1201 tttcaaatcc gcatcagaat aaacaacatt atcaatcatt acagataatg gaacaattgt
     1261 aatatctaat tgctttacta gttcaggttc aatagtaaca gatgaatcgg ttacaatctt
     1321 aatttttgtc atagtatcaa tctttctatt ttaggattca gattggtttc cttacttcta
     1381 attatatcaa aaaaaagatt aaaaatccta atggagtcaa tcaaattttc cgtaaaattt
     1441 gatataatca acttataaga aaagaggtgt cctatgatta aaaaaattta ccccattttt
     1501 accattttac taggtgctgc tatttatgct tttggactga cttattttgt agttccccat
     1561 catctctttg aaggaggggc gacaggcatt accctcatca ccttttatct ttttaaaatc
     1621 cctgtttccc tcatgaacct gctgattaat attccccttt tcatcctagc ttggaagatc
     1681 tttggagcca aatccctcta ttctagttta ctaggaacct tagctttgtc cgcctggtta
     1741 gctttttttg agcatattcc ccttcatatt gatcttcaag gtgatttact aatcacagcc
     1801 cttatagcgg gaatcctatt gggaattggc cttggaatta tttttaatgc tggaggtaca
     1861 actggcggaa ctgatattct agctcgtatt ctcaacaaat acactcatat atccatagga
     1921 aaactgctct ttatcttaga tttttgtatt ctcatgttga ttctcctaat cttcaaggat
     1981 ttgagattgg tttcctacac gcttttgttt gattttattg tttctcgtgt tattgatttg
     2041 attggtgaag gaggatatgc cggcaaaggc tttatgatta tcacaaaacg tcctgaccaa
     2101 cttgctaagg cgattaatga tgacctcgga agaggtgtta cttttatttc tggtcaaggc
     2161 tactatagta aagaaaattt gaaaatcatc tactgtattg tcggaagaaa tgaaattgtg
     2221 aaaacgaagg aaatgattca tcgaatcgat cctcaagcct ttataactat tacagaagcc
     2281 catgaaatcc taggagaagg cttcaccttt gaaaaagaat aaaaagaggt aatgtcgtga
     2341 cctcaaaagt tagactaaat catctatctt ttgggttaca gacaacctct tttttatttt
     2401 atttactcaa gctcttaata ccaattccga gttacttctt catcagcctt taactgatcc
     2461 actaattggt caactgagtc aaatttggtc atatctcgaa tgcgatcaag ccaataaacc
     2521 atgacggttt ccccataaat atcttgatta aaatcaaaaa tattgacttc aaaacgtgct
     2581 tcttctccat caaaggtcac atttttcccg acactagcca tagcacgata cttctgtctc
     2641 tgaatctcaa catcaacaac ataaacgcca tctgctggca tataagtacg gtctaaaagc
     2701 actaaattcg ctgtcggata accaattgta cgaccacgag cattaccatg aaccaccata
     2761 cctcttgatg gaagcggtgc ccccaaaagt tttcctgctt ctttcacatt tccatctaaa
     2821 atagcttgac ggatacgagt tgaactaatc tttcctttct catcttctac aggtggaaca
     2881 atgataactt ctccatcaaa gtaatccttt aaatcttctg ctgttttttt gtcagaacca
     2941 aatgtataat caaaacctgc aacaataatt ttggcattca tagccttgat ataagttgca
     3001 aagaattctt gtgcagtgag actagcgaat tgactactaa aatcaaggag atataattct
     3061 tctacacctt cgcgctttaa ttttctttca cgttcagcag ggttcaaaat atgcaaaaac
     3121 aaatctggat gataaggctc taaagcgatc tttggagatt cattaaaggt cataacgacg
     3181 ataggcaaca aatcctttct cgcagccttg ttggcaacac gaaataattc ttgatgcccc
     3241 ttatgtatgc catcaaaata gccgagaaca acgactgaat cagatggtgt gccaatatct
     3301 ttttggtttt ttataggaat agtaataatc ataaaataat tatatcatag cgatagctat
     3361 ttctggaaca gaaaatctga aatgttgttt ttttcacatg aagtgtacct gttttcaaaa
     3421 agcactttat tctatcgttg cttaactatg aactttgcaa tattcttctc aaaaacttgt
     3481 aggacatctt caaaattttg caaggagtga ttagacttgt tcggtaacca taaagtgtca
     3541 tactatgctt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccgaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc
     3721 actttccctg atgacaaaaa aagccaaagc agtaaagaaa aactagatga ctgctttcca
     3781 acaacttcca tctagtgtgc ttcagactgg gctatttttc tctccatctg ttagcttgga
     3841 ttctcagacc gtttcagcta aagaatatct tttcccttat cagaaggaac gggctcaaac
     3901 cactcagaca agtgaaggga cgacaagcca atatttgaaa ccagatagca gtttttatag
     3961 tcaattgaaa taaaatctga agaaatcgag taggaaactc atatcaattt ttaacagtgt
     4021 tctattccag attcatactc aatgaaaatt aaagtgcaaa ctaggaagtt agccgcaggc
     4081 tgtacttgag tacggcaagg tgaaactgac gtggtttgaa tttgattttc gaagagtatc
     4141 aatccactat acatattaaa aagtatgggt atcaaaacaa aaaaacaggc tctccgaaaa
     4201 ctcggaaagc cttattttaa gctgtttcta gcttcctcac ctttacattt caaggttcgg
     4261 gataaaaggt tcaatggacc tttttattta gcgattgggt aaacagaaac ttgtttttta
     4321 tcgcgtcctt tacgttcaaa gcgtactacg ccttcaactt tagcgaacaa agtatcgtct
     4381 ccaccacgac caacgtttac acctggatag atgtgtgtac cacgttgacg gtaaaggatt
     4441 gatccacctg ttacagtttg tccgtcagct gctttagctc caagacgttt cgcttgtgaa
     4501 tcacgtccgt ttgatgtaga acctccacct tttttgtggg cgaaaagttg caagttgtta
     4561 agagtcattt ttaacataat gttttcctcc gtgttagttt tctgtgataa ctctggtttg
     4621 gacgaactca gaagagttct ccgataagtt tgccatacct aagaaaaatg attcaaagaa
     4681 taactgggtc atttctctct ggtgtgaagg aagatctttt ggtatttcaa ccatcagata
     4741 gccaccttca tcttcgttta attctaggat tggttcatag cctgcaaatt tctcaataga
     4801 attgataaag ttaatggcaa gcgtagaaac cgatgcacac acgacatcta agccgtattc
     4861 gccactctcg gcgtgtccag taatttccgc actcctcagc tcgccatctt cggctctctc
     4921 aaagactgct tgtatcatgt gttctcctta aaattaagcg ttaattgcgt tgatgacaac
     4981 ttttgtatat ggttgacggt gaccttgttt acggtggcta ccttttttag gtttgtactt
     5041 gtaagtaaca actttctttt gttttccttg tttttcaaca gttccaacta cagtagctcc
     5101 agcaacaagt ggagttccga caacagtgtt ttcaccacca acaagaacaa cttcgttaaa
     5161 agtaacttct tgaccagctt caacgttcaa tttttcaatg taaactgctt gaccaacttc
     5221 aactttaact tgttttccgc cagttttgat aattgcgtat gtgctcatta tgcacctcct
     5281 atgattttta tgggtttccc cgattttttt gtgaagactc gcctagcatc gtgggacaaa
     5341 ccacttaaac ttgaataatc aagcaacgat gttcgtgcgg ttgcacagga tcgtgcatag
     5401 tcaactcttc aagtgtagca tatttcctat tttcttacaa gtaataacac ctaaaatcaa
     5461 gctttttctt ttactttttt ctgccactag gcaaaaagca tactgagata aaaaatgctc
     5521 atcataatag gaacaccaag aatggtcttt tcatgataga aaatcgtcaa atagactgaa
     5581 aagacaacgc caaggacaaa actactaagc aggctaacaa atatgaaccc ttcacgcaaa
     5641 aaaggagtgt gcttagttcg gaaataatct ccaaaagcta gcattgttcg tttgatattc
     5701 cctgtcataa aggcattatt gtaggcaata cccgaaacct caccaaaagc agttgtcacc
     5761 agtcccatac agaaggccaa gggcggcact agatagatat tatctacagt ttgtggcaca
     5821 aaaccaataa ttattgatag gattgctaaa ggaatcaagg acagaataga ttttttcaca
     5881 attctcaatt tttccttata aatcgttaat aaaaagactc ccatcataaa cgctattaag
     5941 gttaaaagct tatccctaat atccgaaaca ttattttgta tgagctctac cgaaagaaag
     6001 acaacatttc cagcttgtcc agctacaagg gtattcccgc gaacaataaa agtgtaagca
     6061 tccacatatc cagcacaaaa cgtcaaaaaa gtgctaacct tttagactga cgtgatattt
     6121 ttcttatagg taataacctc attttccctc ccattgtatt ttctcttaga aatattgtac
     6181 cattttcttt ctaaaaaatc gtaggctacc atttagattt tactattagc ataaaaataa
     6241 taatagacaa ctatttatcc aaaaatagat agaggtaaca tgtttgcaaa caaagcatac
     6301 gaacctttag taaaatcatt tccatgaaac tagaatagag cccctcttag caaaaatcat
     6361 tattttaatt tatttctaat cactccttga cataaataac tctcaccaat aaaagactat
     6421 gtcttaaaaa aatggtataa taaaatcaat acttggactt gatggctatg ctactaataa
     6481 caattaggag agaaaatcag gcacttgtta acaacaagga ttatcccctt gagatgaaag
     6541 gaactttaga aatcttatga tgaacatgca aaacatgatg cgtcaagcac aaaaacttca
     6601 aaaacaaatg gaacaaagcc aagctgaact tgctgctatg caatttgttg gcaaatctgc
     6661 tcaagatctt gtccaagcaa ccttaactgg cgataagaaa gttgtcagca ttgatttcaa
     6721 tccagctgtc gttgacccag aagaccttga gactctttct gatatgaccg ttcaagccat
     6781 caactctgct cttgaataaa tcgatgaaac tactaagaaa aaactgggtg ctttcgctgg
     6841 gaaattgcca ttctaaaaac aaggagctag aacaatgctt gtcgataaca aaggctaaga
     6901 aaggtgcaaa aattataaaa aacgcatagt atcaagcaac ctaaaacttt gggctctata
     6961 atatttgtag tgggtaaatc ccctatggat attacggagc ctatttttgt gtagaaaaaa
     7021 agtcccatat gacctataat gaaaagcgac aaaacaactc attagaaaga atcatatgga
     7081 acaattacat tttatcacaa aattactaga cattaaagac cctaatatcc agattttaga
     7141 catcatcaat aaggatacac acaaggaaat catcgccaaa ctggactatg aagctccatc
     7201 ttgtcctgag tgcggaaacc aattgaagaa atatgacttt caaaaacctt ctaaaattcc
     7261 ttatcttgaa acgactggta tgcctactag aattctcctt agaaagcgtc atttcaagtg
     7321 ctatcactgt tctaaaatga tggtcgctga gacttctatc gtcaagaaga atcatcaaat
     7381 tccttgtatc atcaaccaaa agattgatca gaagctaatt gaaaagactt ctatgaccga
     7441 cattgatcat cagttgtcta tttcaacttc aactgtcatt cgcaagatca atgattttca
     7501 ctttgagcat gatttttcgc gtcttcctga gattatgtcc taggacgttg aaacagtctg
     7561 gggagtgact gtttcaatcg ggagatagag atgagcttta ttgctcagga ctttgataag
     7621 ctcaatatca taactgttct tgagagcaga acacaagcca tcatccgaaa tcccatgaat
     7681 acaaggctat caagcgatac tgaaagctca ttcaacaaga tagtcagaaa ctgagtgata
     7741 aacgatttta tcgccctact tttcgtatgc acttgactaa taaagaaatt ctagataaac
     7801 ttttgagcta ttccgaagac ttgaaacacc actataatct ctatcagctc ttgcttttcc
     7861 acctcttttt cagactctgt ttaaaacctt cctcaaagat aaagagaaaa tcgtcaacgc
     7921 ccttcaatta ccttattcca acgccaaact ggaagccacc aataatctca tcaaacttat
     7981 caagcacaat gcctttggtt ttcgaaactt tgaaaacttc aaaaaacgga tttttatcgc
     8041 tctgaacatc aaaaaagaaa ggacaaaatt tgtcctttct cgagcttagc ttttcttcaa
     8101 cccactacag ttgacaaaga gccagaaaac gcataatagc aggtgtcaag acacttaata
     8161 ttatgcgttt tctcatgaaa aaattctctt ttcatactca tttaaaatca aaaagggaat
     8221 ttatcgtttt acggacatgt atattacaga tttctatagg tcgtgtatag acaggatatc
     8281 atcgcttgga agttttcctt tttgacacca atcagtaatt tagttctcag gaattaatgg
     8341 cagtgctttt cgtacatagt ttcataacta cagtatagca tagtatatcg ctttatagtt
     8401 ttcactattg atgaactgct tgagctgctg tgatgagggt caacttgtaa acatcatctg
     8461 cattacatcc acgagaaaga tcattaactg gcttgtttaa accttgcaaa acaggtccta
     8521 cagccgcaaa gccacccagg cgttcagcca tcttgtaacc gatatttcct gcctcgatac
     8581 ctgggaagat gaagacattt gcttgaccag ctaccgtact tccaggagct ttcagagctg
     8641 cagtttcagg aacaaaggct gcatcaaatt gcaactcacc atcgatttca aggtcaggac
     8701 gcaagtcgtg agcaatttta gttgcttcaa cgaccttatc aacgctttca ccaaaccctg
     8761 aacctttagt agaatagctc aacatggcaa ttttaggttc gatgccaaac atcttagctg
     8821 tgattgctga gttgatggca atttcagcca aggcttctgc atctggattg atgttaatgg
     8881 cacagtctcc aaataggtaa cgttccgtac cacgaaccat gaggaaggct cctgaagtac
     8941 gagttacatt tggacgagtt ttgatgattt gtagagctgg acgaactgtt gaagctgttg
     9001 agtgaatcgc tcctgacacc attccatcaa ccaagcccaa gtaaaccaac atcacaccaa
     9061 agtagttgac atcttcaacc aaaaccttgc gtacatcttc ttcagtcatt ttgcccttgc
     9121 gacgctccac caaggcagaa accatttctt caaattgagg ataatgttga gggtcgatga
     9181 cctcataacc atccatgatt ccttcaattt caagataaat tttaattttt tcaggatttc
     9241 caagcaaaac aggaatcact tctgtttctt ttactaagcg ttttgttgct tgaagaatac
     9301 gaggctcttc cccttcaggg agaacgatac gagcattttt accaacaagg ttggctttga
     9361 gactttcaaa aacttccatg agttttctcc tttaagataa taattatact ctgagacagt
     9421 ttttatagag tattagttga taactgggta ataaggttac tgaaatcatc cggcaaggga
     9481 ctttctaact gcaagtcttg ctctaaaaat ggatgataaa aggataggta atggcaatgc
     9541 agagcctgac gttgaatacc atcttccaga ctaccaccat acaaatcatc tcccagcaaa
     9601 ggaaaaccga tataagaaaa atggactcgg atttgatggg ttcgaccagt gtgcaggtga
     9661 atatagacca agtgaatatt tccataagaa gctacaatct tgtatgaagt atgggcatac
     9721 tttccgcctt tagccactcg tctggtaata atggaatctt catcacgcgc aatcggagca
     9781 ataatttccc cttctggctc caaatgtcca tctcccttaa ccaaagcaaa gtagcgtttc
     9841 tcgatagatt tcttctgcaa ctgcttgtct aatcgtgcat gggcataacc gtgcttggca
     9901 aagagcatca agccagaagt gtccctatct agtctggtaa caatgtgaac ctgctgattt
     9961 tcataatttt gcttgacata gtaacccttg ataaaattgg caatggtatt agagtgattg
    10021 acactaggaa tagaagccac tccatagggt ttattcaaga ctagaaagtg gtcatcctca
    10081 tagagaatat ctaatggatg ctcaatagcc tccaaggttt caaagccttc ctcagcggga
    10141 atgtaaatgg taacgtagtc tccaacgtcc aatagatacg ttgcattttg cggttgatta
    10201 ttgaccagaa tcgctccacc tcgaaactta atcttagcca gcaatccctt agaaacctcg
    10261 tgctttttta aaaaggtctt aaccttgaca tgttcatctg cgataaattc aaacctcatt
    10321 catccacctc accgataaag gcatccttaa cacggttcca gaaactggta tggctaggag
    10381 tcgcgacaaa gtgaatctta tgatggtcga tttgatactc aatacgctca atattacgga
    10441 aagaataaac gctattgtca accgaaatag tatgataatc gtttcttgtt ggaataagtt
    10501 caatcttatc cttcttaggc acaataatgg aagagcccag tgttcgataa acacgattat
    10561 taaggctggc aatttccgtt aattgcaaag cttcaatggt agggtgtaaa acagcaccgc
    10621 caagagactt gttataggca gtactaccag tcggtgtcga aactgttagc ccgtctccac
    10681 gaaaacgttc aaagggaaca ccatttatta caatatctgc caccatggtt cgatcagacc
    10741 tgcggatgct ggcttcgttg agtgctctga aaatcttaac ttcaccattt tcaagaaaga
    10801 ccttcacatt cagaacaggg taagaaaccc ttgccccagt atctagctgc aaattagtca
    10861 ctagcttgtc caactcaaaa tcacgataat ctgtatagaa gcccaaatgt ccagtatgaa
    10921 gaccgataaa gcggaccttg tcaagctgat tttcgtactt atgaaaggcc gacaagagca
    10981 taccatcccc gccaatggaa atgacaatat ccggattggt atcattgagt ataaactgat
    11041 ttctcttcaa acgatctcgc aattcataca aaaccctttg actctgcggt tttctattgg
    11101 ctatcagatc aattcgttta cctgtattct tcatctgtat cgtcactgtt tcctacaccg
    11161 tcatttaatt ttctactcaa aggatcaaaa agtgcctggg cttcttggat atcatcacga
    11221 atttcaccca tttcttcatc caactgatgg gcgattctag ctgtaatttc cagtcgcttc
    11281 ttaatctcat ctgggaaatc cccttggtac ttgtagttga gagaatgttc tatcgttgcc
    11341 cagaaattca tggccaaagt acgaatttga atttctgcca aaatagtctt agctccattg
    11401 atggtatcaa ccgtatattc tactaccaca tgataggaac gatagcctga tgcttttcta
    11461 tgagtaatgt aatctcgctc ctgtatgatt cgcatatcct gacgcttgtg caaaatatcc
    11521 actacttcct tgacgtcatc tacaaactga accatcacac gtaagccagc aatatcctgc
    11581 aaatcgtgtt ccaaggtcgc ataagtaatg ctacgacgag ccattttttc tttgatgctc
    11641 tcaattggct tgactcgacc ggtcacaaac tcaattggag aatgcttatt ttgcttacga
    11701 tattgcttac gaataccacg aagtttaatc tttaactcac caacagcttg aatgtaagga
    11761 tctagaaatt cttcccattc taaggtcata tattctccct tgttctcata ttatccgtca
    11821 aaaatatctt tgattttttc tccagattca tatacaataa atacaatgct tattatacca
    11881 taaatccgct ttcaacgata aaaaaaggta agaaaaatga aacatttaga aattgaattg
    11941 aaaacactat tgaaaaaaga tgaatacaat cgtctaaaag accagttcac aggtgtcact
    12001 cctgttcttc aaacaaatta ctacatcgac acgcttgatt ttgaactgcg agaaaagaaa
    12061 gtcgctatgc gcattcgaac ctttgaagac tgggctgagt tgacactcaa agtcccgcag
    12121 agtgttggaa acatggaata caaccaaaaa ttgcaactaa aagatgctga gaactatctg
    12181 agtaaggaag aacttcctca agggctagta ctggatgaat tggcgaaaca tggtatccaa
    12241 agtaagaact ggcaggttct tggttgtcta acaacgcttc gctatgaaat gaaaacagct
    12301 attggtctca tggcactgga tcagagccga tactttgata tgacagatta cgaattggag
    12361 cttgaagtgg aaaatcatga gcaaggcaaa caggatttcc gacaattttt agagaaaaat
    12421 cagatttcct accaaaaagc tccttcaaaa ttggttcgat ttgtcaaaag tatgaaaaat
    12481 agctgaaata atctccattt tttggtaaaa tagaaaagat aaaaatacac aaatcccagt
    12541 tcatatatgt aaggtaaata taactaggat ttataaagtt tacagaggac ggtctataat
    12601 gtcagataga aaaaacatga aacttttcgc actcaactct aaccaagaga ttgcacaaaa
    12661 aattgcccaa gctgttggtg tcccacttgg aaaactatca tcacgtcaat tttcagacgg
    12721 agaaatccaa gtaaatatcg aagaaagtgt ccgtggttat gatgtttaca tcatccaatc
    12781 aacaagtttc cctgtcaaca accacctaat ggaattgtta atcatggtcg atgcttgtgt
    12841 gcgtgcaagt gcccacagta tcaacgttgt ccttccatat tttggctatg cacgtcaaga
    12901 ccgcattgct tgtcctcgtg agccacttac agcaaaacta gttgccaata tgctggttaa
    12961 ggctggagtt gatcgtatcc tgactcttga tttgcatgcc gttcaggttc aaggtttctt
    13021 tgatattcca gtggataatc ttttcactgt tcccctattc gcaaaacatt actgcgataa
    13081 aggattgctt ggttcagatg ttgttgtcgt tagccctaaa aattcaggtg tcaaacgtgc
    13141 gcgtagcctg gctgaatatc ttgatgctcc tatcgccatt atcgactacc ctcaagacga
    13201 tgcaactcgt aacgaaggtt atattattgg tgatgttgaa ggtaagaaag ctatcttgat
    13261 tgatgatatt ttaaatacag gacgtacctt ctctgaagct tctaaaatcg ttgaacgtga
    13321 aggagctaca gaaatttatg ctgtttctag ccacggtctc ttcgtcgagg gagctgctga
    13381 gcttcttgac aatactaata ttaaagaaat tcttgtgact gattcagtag caacaaaaga
    13441 aaaaactcct aaaaatgtat gctacatcac tgctagtgag ttaattggtg atgctatcgt
    13501 ccgtattcac gaaagaaaac cagtcagccc actctttgcc tacaataaaa agaaataagg
    13561 tgattctttg atttatttgg acaatgctgc aacgactcct atgtcagcag ttgctatttc
    13621 agctatgacc aaggttatgc aagaaaccca cggaaatcct tctagtattc atggtcatgg
    13681 tcgtcaagct ggcaaactct tgcgagaagc ccgtcaggaa ctagcccagt tactaaggac
    13741 aaaacctcaa catatctttt tcacttctgg tgggactgaa ggcaataata ctaccatcat
    13801 tggctactgt cttcgtcacc aagaacaagg aaaacatatc atcacaactg ccatcgagca
    13861 ccatgctgtc cttgaaacaa ttgattactt ggttcaacac tttgggtttg aagcaaccat
    13921 tatccagcca gaaaatcaag aaatcacagc ccagcaaatt caaaaggctt tacgtgacga
    13981 tacgattttg gtttctacta tgtttgccaa taatgagaca ggaaacctac ttcccatcgc
    14041 tgaaattggc caaatactca agcaacaccc tgctgcctat catgttgatg cagttcaggc
    14101 tattggtaaa atcccaattc attcagaaga attgggcatt gattttctca ctgcttctgc
    14161 ccacaaattc catggtccta agggaatcgg ttttctctac gcatctagca tggactttga
    14221 ttcctatcta catggcggag atcaggaaca gaaaaaacgt gcaggaactg aaaatctgcc
    14281 tgccatcgta ggcatggttg cagccctaaa agaagaccta gaaaaacaag aagaacattt
    14341 tcaacatgta caaaatctag aaactgcctt tctggcagag ctggagggca ttcagtatta
    14401 cttgaataga ggaaaacatc atctccctta tgttctcaat attggatttc ctggtcagaa
    14461 aaatgacctc ttactccttc ggctagattt agctggaatt tcaatctcta ctggctcagc
    14521 ctgtactgca ggcgttgtcc aatccagcca tgttcttaaa gccatgcatg gcgcaaattc
    14581 agaacgcttg aaggaatccc ttcgcatcag tttgtcgcca caaaataccg ttgaagacct
    14641 acaaaccctc gcaaaaacct taaaagaaat tatcggaggt tagccatatg gcatttgaaa
    14701 aaatcattca gttaaaaaat tgtcgttacg attacactct tagcccttct gttaaaaaat
    14761 tcaccctcaa agataacacc ttttttgaaa ctaaggttgg taactatgaa ctgactcgcc
    14821 ttttggaaaa agtgccaaac agcggtgaag gcttccaact caaaatcatc attaacaagg
    14881 aacttacagg ggctaaaatc aatatcactg acaagtttgg ccttcgtcta gttgatattt
    14941 tcaaatcaga agaccaccat attcatcagg aaaaattcta cttcctcatg gatagcttgg
    15001 tagaacgtgg tgtctttaca aaatcggaaa gatagagcca aaatgtttga actgacctat
    15061 aaggactgct atcatgtaga gcgtactctc aagtatgagg atcatgaggc tctcatgttg
    15121 actttgtcag gatgtgtaac cttaccagat acactttatg tgacttctct gacttttagg
    15181 ggcaaaaaag tttatcaggg gctggtcgga gacctctacc gttttctatc tcatgcagat
    15241 tttttacatc aaaactaaga tttttcttag ttttttctta tttttgttga ttttttcaca
    15301 atgtttctat aaaatagaag aatagaaagg ttgtgatttt gtgaaagata aacagtttgc
    15361 tattccaaaa gctacagcaa aaagactctc tctctactat cgaattttta agagatttca
    15421 tgcagaaaag attgaacgtg ccaactctaa gcaaattgca gaggctatcg gtattgattc
    15481 agcgaccgta cgtcgtgatt tttcctattt tggtgaactt ggtcgtcgtg gttttggcta
    15541 tgatgtcaaa aaattaatga cattttttgc cgatttgctc aatgacaact ctattaccaa
    15601 tgtcatgctg gttggtattg gaaatatggg ccatgccctt ctccactacc gcttccacga
    15661 acgtaacaag atgaagatta tcatggcctt tgacctagac gaccatcctg aagtcggtac
    15721 ccaaactcct gacgggattc ccatttacgg gatttctcag atcaaggata aaatcaagga
    15781 tgctgatgtg aagactgcta tcctaactgt tcccagcgtc aagtcacaag aggttgctaa
    15841 tctcttggtt gatgctggtg tgaaaggaat tctcagtttt tcaccagtcc atctgcattt
    15901 accaaaagac gtggtcgttc agtatgtcga tttgacaagt gaactccaaa ccctcctcta
    15961 cttcatgcga aaagaggatt agaaagcgaa aatcatttta tgaaaaaacc agttattggg
    16021 attacaggaa acgaaaaaac tcatccagat gatgacatca tgatgagcta cgcagcaaaa
    16081 ggctttgttg aaggcgttaa agatgctgga gggattccta tcatcctacc gattggtgat
    16141 caagaaatgg cctgccacta tatcagtttg attgacaagc tcatcttgac aggtgggcaa
    16201 aatgtcgatc caaaattcta tggcaaaccc aaaaccattg atagcgatga ttatcacctt
    16261 caaagagata tcttcgaact ggccctcatc aaggaagcta ttaaacagaa aaagcccatt
    16321 ttctctgtct gccgtggtac ccaactcttt aacgttgcca tgggtggaac tttgtaccaa
    16381 gatatcgaag accattggca ggattcttct gttgagtaca caactcaacg cttggtaaca
    16441 gaaccagata ccgttctcca agaaatctat ggagaaatct ctcatatcaa ctccttccac
    16501 caccagagca tcaaggactt agcaccaaat ttaaaagttg tggctcatga tcctaaagat
    16561 ggtatcattg aggctgtcat gagtacggat gatgtcgcct ttctcggtgt ccaatggcat
    16621 ccagaacttc tttttgaaaa tcgtcccaaa gataagaaac tctttgacta tgtcgttaat
    16681 gaactttaga ttaaatctgt cttttcacga taactaaagt aattagaatg agagacaatc
    16741 aaatggtcca agagaacaat ccccatcagt tcgcaggctt ctttaacaag tttagtgaca
    16801 tgatcatcat tttggctagg cgctaccgct cctgaaagat gattgtggac caagataaga
    16861 gaagtcgcca tatgcttgat tgcatagtgc agaatctctc gcggttcagc gatactacga
    16921 gttacagaac cgataaaaat ggtctgctga tggatgattt gattttgagt attgagatag
    16981 agtgccacca ggtgctcttg ttttttatcc cctaattcct gctgcatctt cttggccaac
    17041 ttttgactgc tgagaatact ttccatttca agagtctcgt gtttgtgaat acgatgcccc
    17101 agttcaatca tagcttgtaa ttctatggcc ttaacacgcc caataccaga caaactctgc
    17161 aattcctgca gggtcatttt tttcaaatcc gttaggcttg aaagattgtt caagactttt
    17221 tgggcaattt caaaaacgct agcttgacgt gttcctgtcc tgagtaaaat agctagcaac
    17281 tcttggttac taagcgcttc aactccttcc ttggccagcc tttctcttgg taatagtgaa
    17341 tcttcttgga atgaaatact gtacataaaa atcctcctca ctttattatt cgtgagaagg
    17401 atggaaaatt agattttttt ctcaattgga gccacactgg ctaaaagttt tttcaaacct
    17461 acttctggga aattgatttt caattcctgc ctagcaccgc tacctgaaac ttccagaaca
    17521 gttccctctc cccatttctt gtggagagca atgtcaccaa tggaccaatt tgcctcgcta
    17581 gatgctgatt ttgcgccagc tgtaaattga ccaaatggaa gaacgcttga ctggattgat
    17641 tttggggcag caccgcgttt acggtcttga agagcctgag ccaaactcat accttgacca
    17701 aaggaaatac taccactgct atatgatgcc ttaaagcttg tatttgcagg acgagccaga
    17761 ccttgatact caagcaagtc tgaactgatt tcgttaataa aacgagtcgg acggttataa
    17821 ttggtacgac caaaaagcaa gcgtgagttg gcattggtca gatagagaat tttctctgca
    17881 cgcgtgatac ctacataggc tagacggcgc tcttcttcta attcatctgg atcttcagtc
    17941 gcacgactaa gtggaaagac attttcttcc atcccaatca aaaagacaac tggaaattcg
    18001 agacctttgg cagcatgcag ggtcatcaag gtcacttctg atgtctcctg actacctgaa
    18061 tctgtgtcgg caatcaaagc caagtcattt aagaaacgac tcagtttgtc cagaccagtt
    18121 tcctcttctg tcacatcagt ggtgtcatca aagttcttcg taacagaaag aaactcttcg
    18181 atattttcaa cccgtgcctt gctttctaga gtcgcttggg cgttaagaat atcgacataa
    18241 cctgtttttt ctaggacgga ctcaaccaac tctgtaatgt ttaagtggtc tagctgctcc
    18301 cgcaaatcaa gcatcatatt ggcaaaatcc cagatagatt gggctgcctt acccttgata
    18361 ccagacaaca taatattagc agaagcatcc agcatagaca tattttgcaa atttgcaaaa
    18421 tcacggattt tctcaactgt acctagacca attccacgtt taggctcgtt gataatacgc
    18481 tcaaaactaa tattgtcact caaattagca ataaggttga gataagcaat aatatcgcga
    18541 atttccttac ggctgtagaa tttggttccg ccaaccatgg tataaggaat gttagacttg
    18601 agcagggctt cctcaattgt acgggactga gcattagtcc gatagagaac tgcaaaatcc
    18661 ttatgaagga agttttgact gcgactaagt tcatcgatgg ttctggctac aaatacagcc
    18721 tcatccagct catcatcggc acgatagtaa acgatttgct ccccatcagc gttttgagtc
    18781 cagagatttt taggacggcg atttttatta tttttaataa cctcgttggc cgcttggaga
    18841 atggttttgg ttgagcggta attttcctcc aacaaaacaa ccttggcttt ggggtaatcc
    18901 ttttcaaagt ccaagatatt ctgcatatca gcaccacgcc aaccgtagat agactggtcc
    18961 gcatccccaa ccacacagat atttttaaaa cgggaagcca agagtttgac taattggtac
    19021 tgagcgtggt tggtatcttg gtactcatca acgtggatgt attggaattt ttgctggtag
    19081 taggtcaaaa catcaggatt ttgatcaaag agacgcaagg tcagcataat caaatcatca
    19141 aagtcaacgg attcagactg acgaagttct ttttgatagg ctgtataaca ctgggccaca
    19201 atttgcgtat acatatcgcc agcttgggca gcataagcaa catcatcaat caaatcattc
    19261 ttagcattgg aaatggtccc caaaatagtt cgttcattcc attttttagg atccaagttc
    19321 aactgtttga gaatacgttt catgagcgtt cgctgttcac caggatccac aattgtaaaa
    19381 ttacgattgt agccaatatg gtccgcatcg cgacgcaaaa tacgcacaca catggagtgg
    19441 aaggtcgcaa tcagacagtc ctgagtcgct ggattgaggc tataagcacg ctctttcatc
    19501 tcacgcgcag ccttgttggt aaaggtaatg gccaagatat tccaaggatt gaccagcttt
    19561 tcatcaatca aataagcgat acggtgggtc aaaacacgag tctttccaga accagcccct
    19621 gccatgatta gcaagggacc ttctgtcgtt tgcaccgcct cagcctgacg gtcattcatt
    19681 ccatttaata atgcgttcat cttctcttcc ttactcttga agtcaatatt tctattatat
    19741 cagaaatcag ggaaaataga aactttacgg ggagtagcaa aatatagtgg attgaaacta
    19801 gaatactaca ctgtgggttt ctaaaacact cgactttttc acccaatttt ttcataaact
    19861 agctcaatac ctcaatagac ttcctgcaaa actagaatcc tagttcatga ttgataatac
    19921 cagcaatcaa attcattcgt aatccgaagc gtttacgatg atttcgatag gttgttgaaa
    19981 acattttaaa cgtttttact ttggcaaaga tgttctcaac cttgcttctc tccttagata
    20041 gcgcatggtt acaggcttta tcttcagctg ttagcggctt gagtttgctg gatttacgtg
    20101 gagtttgtgc ttgaggatat atcttcatga gcccttgata accactgtcg gccaagattt
    20161 taccagcttg tccgatattt ctgcaactca ttttgaacaa cttcatatca tgactatagt
    20221 tcacagcgat atccaaagaa acaattctcc cttgacttgt gacaatcgct tgagccttca
    20281 tagcgtgaaa tttcttttta ccagaatgat tcgctaattc tttttttagg gcgattgatt
    20341 t
//
LOCUS       DBJKQU010000038        20287 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.038, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000038 DBJKQU010000000
VERSION     DBJKQU010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20287
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.038"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            1..117
                     /locus_tag="ACSUUC_001506"
                     /pseudo
     CDS             1..117
                     /locus_tag="ACSUUC_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            257..1747
                     /gene="lysS"
                     /locus_tag="ACSUUC_001507"
     CDS             257..1747
                     /gene="lysS"
                     /locus_tag="ACSUUC_001507"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HHQ8054697.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALCEQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKVIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            2371..3507
                     /gene="lctO"
                     /locus_tag="ACSUUC_001508"
     CDS             2371..3507
                     /gene="lctO"
                     /locus_tag="ACSUUC_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HHQ8054698.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCNVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      3759..3847
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4062..4730
                     /locus_tag="ACSUUC_001509"
     CDS             4062..4730
                     /locus_tag="ACSUUC_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HHQ8054699.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(4727..4954)
                     /locus_tag="ACSUUC_001510"
     CDS             complement(4727..4954)
                     /locus_tag="ACSUUC_001510"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054700.1"
                     /translation="MKIKEQTRKLTADCSKHCFEPVDKTDEVSSKHCFEVVDRTDEVS
                     NHTYGKVKLTWFEEIFEEYYLIKFVNIMSLL"
     gene            5057..5839
                     /gene="thiM"
                     /locus_tag="ACSUUC_001511"
     CDS             5057..5839
                     /gene="thiM"
                     /locus_tag="ACSUUC_001511"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HHQ8054701.1"
                     /translation="MTSLKLLKKKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGMDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            5841..6470
                     /gene="thiE"
                     /locus_tag="ACSUUC_001512"
     CDS             5841..6470
                     /gene="thiE"
                     /locus_tag="ACSUUC_001512"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HHQ8054702.1"
                     /translation="MFHKELLKLYFICGTTTCQGKDLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      6679..6767
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            7029..7589
                     /locus_tag="ACSUUC_001513"
     CDS             7029..7589
                     /locus_tag="ACSUUC_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHQ8054703.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNMLSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIRLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            7590..8975
                     /locus_tag="ACSUUC_001514"
     CDS             7590..8975
                     /locus_tag="ACSUUC_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHQ8054704.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEKRNQGRSFLLISHRLDPLISVVDYWIEMTSQGLSHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            8977..9627
                     /locus_tag="ACSUUC_001515"
     CDS             8977..9627
                     /locus_tag="ACSUUC_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HHQ8054705.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            9638..10330
                     /gene="tenA"
                     /locus_tag="ACSUUC_001516"
     CDS             9638..10330
                     /gene="tenA"
                     /locus_tag="ACSUUC_001516"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HHQ8054706.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            10335..10859
                     /gene="thiW"
                     /locus_tag="ACSUUC_001517"
     CDS             10335..10859
                     /gene="thiW"
                     /locus_tag="ACSUUC_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HHQ8054707.1"
                     /translation="MRKHQLQVHKLTILSMMTALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            10859..11662
                     /locus_tag="ACSUUC_001518"
     CDS             10859..11662
                     /locus_tag="ACSUUC_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HHQ8054708.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            11655..12287
                     /gene="thiE"
                     /locus_tag="ACSUUC_001519"
     CDS             11655..12287
                     /gene="thiE"
                     /locus_tag="ACSUUC_001519"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HHQ8054709.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(12497..13288)
                     /gene="thiD"
                     /locus_tag="ACSUUC_001520"
     CDS             complement(12497..13288)
                     /gene="thiD"
                     /locus_tag="ACSUUC_001520"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HHQ8054710.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDAYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLDSVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(13372..13470)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            13654..14049
                     /locus_tag="ACSUUC_001521"
     CDS             13654..14049
                     /locus_tag="ACSUUC_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HHQ8054711.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     SRLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            14060..14431
                     /locus_tag="ACSUUC_001522"
     CDS             14060..14431
                     /locus_tag="ACSUUC_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HHQ8054712.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            14441..16684
                     /locus_tag="ACSUUC_001523"
     CDS             14441..16684
                     /locus_tag="ACSUUC_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HHQ8054713.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTTIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFRLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            16891..18666
                     /gene="spxB"
                     /locus_tag="ACSUUC_001524"
     CDS             16891..18666
                     /gene="spxB"
                     /locus_tag="ACSUUC_001524"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HHQ8054714.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            18777..19124
                     /locus_tag="ACSUUC_001525"
     CDS             18777..19124
                     /locus_tag="ACSUUC_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHQ8054715.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(19241..20152)
                     /locus_tag="ACSUUC_001526"
                     /pseudo
     CDS             complement(19241..20152)
                     /locus_tag="ACSUUC_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         5999 a         3774 c         4415 g         6099 t
ORIGIN      
        1 aatgcagaag gtcatgtaga tttcatcaat acctatgatt tggagccaat ggcgcaacaa
       61 gttattccta aagcagcatt tggctatatc gctagtgggg cggaagatac tttcacttct
      121 ttccagtgat tttagcgtca ggttcttttt agtttttaaa gattatccgt gaatttcttg
      181 cttatttatg ataaaatggg ggtatcgcaa aaaatgactc atcgtattca attttgagta
      241 aaactaggag gatcccatgt ctacagaaca tatggaagaa ctaaatgacc agcagatcgt
      301 tcgccgtgaa aaaatggctg cgctctgcga acaaggaatc gatcctttcg gaaaacgttt
      361 tgaacgtact gcaaattcac aagaattaaa agataaatat gccaacctcg ataaagaaca
      421 attacacgat aaaaacgaaa cagctactat cgcaggacgc ttggtaacca aacgtggtaa
      481 aggaaaagtt ggttttgccc accttcaaga ccgcgaaggc cagattcaga tctacgttcg
      541 taaggatgct gtcggtgaag aaaactacga aatcttcaaa aaagcagacc ttggtgactt
      601 ccttggtgtc gaaggtgaag tgatgcgtac ggatatggga gaactctcta tcaaggcaac
      661 ccacatcaca cacttgtcta aggctcttcg tcctcttcct gagaaattcc atggtttgac
      721 agacgttgaa acaatttacc gtaaacgtta ccttgacttg atttctaacc gtgaaagctt
      781 tgaacgcttt gtcactcgtt caaaaatcat ctctgaaatc cgtcgttacc ttgaccaaaa
      841 aggattcctt gaagtggaaa cacctgttct tcataatgaa gccggtggtg ctgctgcccg
      901 tccatttatc acccaccaca atgcccaaaa cattgacatg gtgcttcgta tcgcgactga
      961 gcttcactta aaacgcctta tcgtgggtgg tatggaacgt gtctatgaaa ttggccgtat
     1021 cttccgtaac gaaggaatgg acgctactca taaccctgag tttacttcta tcgaagttta
     1081 ccaagcttat gcagacttcc aagacatcat ggacttgacg gaaggcatta tccaacacgc
     1141 tgctaaatca gttaagggcg atggcccagt caactaccaa ggtactgaaa tcaagattaa
     1201 cgaaccattt aagcgtgttc atatggtgga tgctatcaga gaaattactg gtgtcgattt
     1261 ctggcaagac atgactttag aagaagctaa agttatcgct gctgagaaga aagttccagt
     1321 tgagaaacac tacactgagg ttggtcacat catcaatgcc ttctttgaag agtttgttga
     1381 agaaacttta atccaaccaa cctttgtcta tggacatcca gtagctgtat ctccactcgc
     1441 taagaaaaat cctgaagacc aacgctttac tgaccgtttc gagctcttta tcatgactaa
     1501 ggagtacggt aatgccttta ctgaactcaa cgacccaatc gaccaactta gccgttttga
     1561 agcccaagct aaagccaaag aacttggtga tgatgaagcg acaggaatcg actatgacta
     1621 cattgaagct cttgaatacg gtatgccacc aacaggtggt ttgggaatcg gtatcgaccg
     1681 tctctgcatg ctcctcactg atacaacaac tatccgtgat gtattgctct tcccaacaat
     1741 gaaataaatt cttatcctct ggctcttacc agaggatttt ttgattcaaa aagagactga
     1801 atttaaggag aaaatgaagt gtagtatatt gaagttgaaa tagtacactt tgatttctaa
     1861 gacattgtta gaaattggtt taaattccct aagcaatttg tgcatgtttt atttcatttt
     1921 acgatagtac gctgaaactg ttcaaaaagt actagaaatt gacttggatt ccccaattga
     1981 tttgttcaga ttcactataa ataaaaaatt aataagtggg ataggaagtt agcgtcaact
     2041 aggatagtat cttgcttaaa cagtatatat gggactgata taagtccata ggtcctatta
     2101 gaggatgttc tggtgtctta ttcacttgtt ttttatagta ttagtagata gaatcagcaa
     2161 ataaaaaagt agttcaaatg cctggcagca aaaaatctca acgattcact taatatagac
     2221 taaggtttag agtttaagga aagtagggct agtatattgt atgaaaaaat aagatggttt
     2281 ttaagcaaaa ctcttgaaaa tgattgaaaa aagagttatt atagttgtat agtaaaaagc
     2341 aaacgcttac ttaatcgagg aggacagttt atgtcataca aaacaagcaa tgcagaaggt
     2401 catgtagact tcatcaatac ctatgatttg gagccaatgg cgcaacaagt tattcctaaa
     2461 gcagcatttg gctatatcgc tagtggggcg gaagatactt tcactttaag agagaatatc
     2521 cgtgccttta accacaagct catcgttcct catacacttt gcaatgtaga aaatccaagt
     2581 acagagattg aatttgcagg tgaaaaacta tcttcaccaa tcattatggc gcctgttgcg
     2641 gcccataaat tagcgaatga acagggggaa gtggcgactg cgcgtggtgt gcatgagttt
     2701 ggttctcttt atacaaccag ttcttactct actgttgacc ttccagagat ttctgaagcc
     2761 cttcaaggga cacctcattg gtttcaattt tactttagta aggatgacgg tatcaaccgc
     2821 cacatcatgg accgtgtgaa ggctgaaggt tataaagcga ttgtcttgac ggcagatgct
     2881 actgtagggg ggaatcgtga agtggataag cgtaatggtt ttgtcttccc agttggcatg
     2941 ccgattgttg aagaatacct gccagaaggt gctggtaaat caatggactt tgtttacaaa
     3001 tcagctaaac aacgcttgtc tccacgcgat gtagaattta tcgctgaata ctctggtctt
     3061 cctgtgtatg tcaagggacc acaatgccgt gaggacgttg aacgttcgct tgctgcagga
     3121 gcttctggta tctgggtaac caaccacggt ggtcgtcaaa tcgacggtgg accagctgcc
     3181 tttgactcgc ttcaagaagt ggcagaagca gttgatagac gtgtgccgat tgtctttgac
     3241 tctggtgttc gtcgtggtca acacgtcttt aaagccttgg cttcaggagc agacttggta
     3301 gctattggtc gccctgttat ttatggcttg gctctcggtg gtagtgtcgg tgtgcgtcaa
     3361 gtctttgaac acttgaatgc ggaattgaag acagttatgc aattgtctgg agctcagacc
     3421 attgaagatg tcaaacactt taagctccgt cacaatccat acaacccaac cttcccagtt
     3481 gaccctcgtg acttaaaatt gtattgataa aacagattgc ctccactgaa tgtggaggtt
     3541 tttcttcgtg tattggaaga ataaattgct atcgaaaact atagtaaaat gaaataagaa
     3601 taggacaaat caatcaggac agtcaaatcg atttctaaca atgttttaga agtagaggtg
     3661 tactattcta gtttcaatct actatataaa gatatttttc ggtcaaatat cttgctaggg
     3721 ctttcatttt ttgctatact ggttcagtaa ttaaataata gagacatttg gggtgcttta
     3781 agctgagatg atacccattg aacctgatac agttaagact ggcgaaggga aatgtgaaac
     3841 gttttttcgt atggcgaaat gaacgatcta atcttgtaag tcaactctaa ttcttgattg
     3901 taattggagt tttttgttta tataaactgg ataggcttgt ttagttagct ctctgcaaat
     3961 gctctcgatg tgctttaaaa ggatcaagtg gaattacgat tttgcttgat atttcttggt
     4021 gttttattaa ttactaacaa gtaaagagag gagaagtaaa tatggaaaca caagactatg
     4081 catttcagcc aggtttgact gttggagaat tattaaaaag cagtcagaag gattggcagg
     4141 ctgcaatcaa tcatcgtttt gttaaggaac tttttgcggg gacaattgag aataaggtct
     4201 taaaggacta tctgattcaa gattatcact tctttgatgc cttcttatcc atgctgggtg
     4261 cctgcgtagc tcacgcagat aaacttgaat ccaagcttcg ttttgccaag caactaggct
     4321 ttcttgaagc agatgaagat ggttatttcc aaaaggcttt taaagagtta aaagtagcag
     4381 agaatgacta tctagaagtg actttgcacc ctgtaacaaa agcctttcag gatctaatgt
     4441 attcggcagt ggcttcatca gactatgccc atcttttggt tatgctggtc attgcagaag
     4501 gtctctattt agactggggt tctaaagatt tggctctacc tgaagtctat attcattcgg
     4561 aatggatcaa tctccacaga ggtcctttct ttgcagagtg ggttcaattt ctggttgacg
     4621 aactcaatcg tgtcggtaaa aatcgagaag atttgacaga acttcagcaa cgctggaatc
     4681 aagcagtcgc tttagaatta gctttttttg atattggtta cgatgtctag agaaggctca
     4741 tgatatttac aaatttgatg aggtaatact cttcgaaaat ctcttcaaac cacgtcagtt
     4801 tcaccttgcc gtaggtatgg ttactgactt cgtcagttct atccacaacc tcaaaacagt
     4861 gttttgagct gacttcgtca gtcttatcta caggttcaaa gcagtgtttt gagcaatctg
     4921 cggttagctt cctagtttgc tctttgattt tcattgagta taaatcattc aacgtaaatg
     4981 aaaaaaattt cttaacgaaa gatagagata aatcgaaatc agtagatcgt ataaagtgaa
     5041 aaggaaggat ttcaatatga caagtttaaa attattaaaa aaaaaagcac cattggtcat
     5101 ttgtataacc aatgatgtag taaaaaattt cacagcaaat ggattagtag cactgggcgc
     5161 ctcaccagcc atgagtgagt ttccagcaga tttagaggat ttgttaaagt atgctggtgg
     5221 tttattaata aacataggaa cattgacaga tgaaaattgg aaattatacc aagctgctct
     5281 gaaaattgcg gagaaatata atgtcccagc agttttagat cctgtagcct gtggagcagg
     5341 agaatataga aaaaaagtag cagatgatct aatcaacaat tataaactag cagcgattag
     5401 aggaaatgct ggcgagattg cctctttagt aggaatggat gtggcatcta aaggagtaga
     5461 tagtgcgggc gtagataata ttgacgaaat tgctctagca gcaaatgaga agttcaatat
     5521 tccaatagta gtaacaggtg aagtggatgc cattgctgtt aatggagaag tggtaacgat
     5581 tcataatggt agtgctatga tgccgaaagt cattgggaca ggatgcttat taggagctgt
     5641 agtagcaagc tttatcggac ttgaaaaagg tcaagaattg aaatcattag aaacagcaat
     5701 gttggtttac aatatcgctg gagaaatggc ggaaaaacgt ccaaatggac atcttcctgg
     5761 aacatttaaa gttgaattta taaatgcctt atatgaaatt acagatgaag atgtcaagaa
     5821 attcaaaaga gtgaagtaag atgtttcata aagaattact aaaactatat tttatttgtg
     5881 gaacgactac ttgccaagga aaagatctat atacagtcgt tgaggaagcc ttaaaaggtg
     5941 gtataacctt atttcaattt cgagaaaaag gtgagggtgc tttagaaggc ttagaaaaac
     6001 ttgagctagc tatccaaatt aaagaacttt gtaaaaaata caatgttcca tttatcgtta
     6061 atgacgatat agatttagca atggaaattg acgccgatgg cgtacatgta ggtcaagatg
     6121 atattggtgt tgatgaaatt agaaaattga tgccagataa aataattggt ctttctataa
     6181 aaaacgagga agaatttcaa caatcaaaag ttgaatatgt agattatgta ggtgttgggc
     6241 ctgtatttga tacccagtca aaagatgatg ctggtggtgc tataggttat gaaggtcttg
     6301 aattgatgag aaaactattg ccacaaatgc ctttagttgc aattggtggg atacagacga
     6361 aacatattaa agacattata aagaccaatg ttgacggcgt ttcaatcatt tcggcaatat
     6421 cgtatgcaaa aaatatagaa aaaactgttc gggaaatgag tgaacaatag atatctatcc
     6481 ttggattcta agtaagtagg attttccttt tttaaaaagc tatgtctaga ttcagcttga
     6541 atggctaatt catcaaacag gtcatttgtt ttttgcaaaa gaaagatctg ctgtctttgt
     6601 gagtgcaagg ctgtatttcc agttcaattt cttgaactag tataaaatgt gtgttataat
     6661 aattacataa ttaaataata aaggcatttg gggtgcttta ggctgagatg atacccattg
     6721 aacctgatac agttaagact ggcgaaggga aatgtgaaat gtttttttcg tatgtcgaaa
     6781 agaactgtct aatcttgtaa gctgaactct aattcgtatc tgtaattaga gttttttctt
     6841 ttacgaaact ggatgaagat gatatagtag attgaaataa gatgcgaaca aatcaattag
     6901 aaaattcaaa ttaatttcta gaaatatttt agcattcctg tgtactgttc taaattcaat
     6961 ctgctataca aagtatttag gtcggtcttc ttgagtgccc cacttttctt ttaaaaaagg
     7021 agttttttat gttgaaaaaa tggcagttaa aagatgttat cttgcttgct ttcttgtcta
     7081 tcttttttgg tggggttttc gttggttcag gatatgtgta taatatgctc agtctactct
     7141 taacacctct tggtttgcag gcctttgcca atgaaatcct cttcggtctc tggtgtatgg
     7201 ctgcgcccat tgctgccatc tttgttccga gagtcggaag tgcaacgatt ggagaagtgc
     7261 tagctgcgct tgctgaagtc ctttatggta gccaatttgg tctaggagct cttttgtctg
     7321 gcttggttca aggtttggga agtgaatttg gttttatcgt aactaagaat cgctatgaaa
     7381 gttggctctc tctaactgct aatagtattg ggattacgct tgttagcttt gtctatgaat
     7441 acattaggtt aggttactac gccttttccc ttccgtttgt cctttcctta cttgtggtac
     7501 gttttatttc tgtttatttc ttctgtacca tcttggttcg tgccattgtc aaactctatc
     7561 atcagtttgc aactggagga aaagcataga tgggtctgga actacgagcg attcagtccc
     7621 caatcttctc tgagccgttt gattttactt ttcatgcgca agcctttacc ttgttagttg
     7681 ggagtagtgg ttcaggaaaa tccagccttt ttcaagtcat tgcccaagtc agttctcttc
     7741 cctatagtgg tcaagtcctg atagatggga gcgaggtcag tcagctttct atcatcgcac
     7801 gtgtccagaa ggttggcatt ctctttcaaa atcccaatca tcaatttacc atggagaact
     7861 tgtttgagga gctgattttc accttggaga atatcggcta tcaccttcag gaaattgatt
     7921 ctaaaatagc agaggttgtc cagcaatgtc gttgcgaggc aatcttacac cgtcccattc
     7981 atcacctatc aggtggggaa aagcaaaaag cagcgctggc tgtcctcttt gccatgaatc
     8041 ctagggtcta tctcttggat gagcccttcg cttctattga ccgcaagagc agaatcgaga
     8101 tattggagat tctaaaagag ttggctcttg atgggaagac agttattttg tgcgaccatg
     8161 atttatctga ctataaagcc tatatcgacc atatggttga gctaagagac ggaaaactaa
     8221 gggaagtgtt tcaaatccct tcctatgaga tgacacaggt tgcttcaaag gaagttgctt
     8281 ctagcccgga actattccat atgaaccgtg tgactggtga gcttggtaat cgccccctct
     8341 tttcaattgc tgatttcaca ttctatcaag ggatttcctg tatcctgggt gacaatggtg
     8401 tcgggaaatc aaccctcttt cgctctattc ttcaatttca aaagtataag gggcgcattg
     8461 catggaaggg gacagtcctg aaaaagaaaa agagtttgta ccgtgatctg acgggtgttg
     8521 ttcaggaagc tgagaagcag tttatccgag taagtctgcg agaggagctt caattagatg
     8581 gacctgattc tgaaagaaat cagcggattt ttcaagcttt acgatatttt gatttggagc
     8641 aggcagtcga taagagtccc tatcaattaa gtggtggtca gcaaaaaatt cttcagctcc
     8701 tgaccatctt gaccagtaag gcttccgtga tcttgctaga tgaacctttt gcaggtttgg
     8761 atgatagagc ctgccattat ttttgcaagt ggattgtgga gaagaggaat caaggaagaa
     8821 gttttctgct cattagtcat cgtttagacc ctttgatttc tgtggttgat tattggattg
     8881 agatgactag tcaggggctc agtcatgtga aagaagtgac cattaccaaa ccacttacat
     8941 ctcagagtag caatacccaa ggggaggtga gatagtatgg tcaaagtagc aacccagaca
     9001 ccgattatca gtctcttctt gctgatttta tccttggaaa catctttcat tccttcgatt
     9061 gctctgaatc tttcggtagt cgcattttgt attctcttta tgctctatta ccgtcgattt
     9121 aaaatgttag cttggatgat catacttgcc attttaccat cttttgccaa ctactgggca
     9181 gttcagttac acggagatgc ttcacaggca gtcatgcttg gaacgagggc ctttgtgaca
     9241 gtttgtatcg gccttgtctt tgtttcctct atttcactaa aagagcttct cttgtacttg
     9301 gctcaaaagg ggctatcacg ctcttggtcc tatgccttga ttgtggtatt caattccttt
     9361 cctctcattc agcaagaaat caagtccctc aaagaagctt gcctattacg tggtcaagaa
     9421 ctgcattttt ggtcgccctt gatttacagt aaggttctga tgacagtctt taggtggcgc
     9481 catctttacc tgagagctct gtctgctcat ggatatgacg aacatgcaca gttgaagaat
     9541 agctatcgga ctttttatat tcctaaaaaa acaaaattaa tctacctgct tttcttttta
     9601 ttgcttcaaa ccagtctatt tttataaagg agttattatg gaatttacag atattgcgat
     9661 ggaattatcc aagaaagctt ggcaggcttc ctttcatcat ccctttattt tacaattaca
     9721 agaggggaat ttagaacctg ccattttccg ctattacctg attcaggatg cctactatct
     9781 gaaggccttc tcagaaatct atcatctttt ggctgataag acttcaaacc aagagatgaa
     9841 aagactcttg aaacaaaatg ctcagggttt agtggagggt gagttattta ttcgccaaca
     9901 atttttcaag gaattggaaa tcaacgacca ggaaatggag caacatccaa tcgctccaac
     9961 ctgttatcat tacatttctc atatttatag gcaatttgca gaaccgaact tagccatcgc
    10021 ttttgcaagc ttgcttcctt gtccttggtt ataccatgat ataggcaaat cacttaatct
    10081 taaaccatca ccaaatcctc tctatcaaca atggattgaa acttatatta cggatgagtt
    10141 agagcaacag atcagagagg agggagcact ggtcaatcag ctctatcgag aaagtgatga
    10201 gacagataag caaaaaatgc tagatgcctt ccacatcagt gttcatatgg aagccaagtt
    10261 ttgggagatg gcttaccaac accagacatg gaagagcgat ttacagtctt tagaaaaagg
    10321 agaagaatag aaacatgaga aagcaccaac tacaagttca caaattgacc attttatcta
    10381 tgatgactgc ccttgatgta gtccttacac ctatctttcg gattgaggga atggcaccga
    10441 tgtccagtgt agtcaatatt ctagcgggaa tcatgatggg acctgtttat gccttggcca
    10501 tggctacagt gacagccttt atccgtatga cgactcaagg gattccgcct ttagctctca
    10561 caggagcgac ttttggagcc cttctagcag gtctctttta taagtacggt cgaaaatttt
    10621 acttttctgc cttgggagaa attgtgggaa caggtattat tggttctatt gtttcctatc
    10681 ctgttatggt actctttaca ggatcagctg ctaagcttag ctggtttatc tacacgcctc
    10741 gatttttcgg agcaaccttg attggtacag cgatttcctt tattgccttt cgatttttaa
    10801 tcaagcagga attctttaaa aaagtgcagg gatatttctt tagtgaaagg atagactgat
    10861 gcaggaattt acaaatccct ttcctatagg ctctagttcc ctcattcact gtatgaccaa
    10921 tgagatttct tgtgagatgc tggcaaatgg gattttggct ctgggatgca aacctgtcat
    10981 ggcagatgat ccccgtgagg ttcttgattt tactaagcaa agtcaggctc tcttcatcaa
    11041 tttggggcat ttgtcagctg agaaggagaa agcaatccgt atagcagctt cttatgcagc
    11101 tcaagtttgt ctcccaatgg tagtagatgc ggttggcgta acagcttcat ccattcgtaa
    11161 gagcttagtc agagaccttt tagactatag acctacggtc cttaaaggaa acatgtcaga
    11221 aattcgaagt cttgttggat taaagcacca cggcgttggg gtcgatgcga gtgctaaaga
    11281 tcaagaaacg gaggatttgc ttcaagtctt gaaagactgg tgtcagacct atcatggtat
    11341 gtctttctta gtcacaggtc ccaaggacct cgtcgtttcg aaaaatcagg tcgctgtact
    11401 gggaaatggc tgtgcagaat tagactggat aacagggaca ggagatttgg ttggagcctt
    11461 aacagccgtt tttctcagcc aaggaaagac tggttttgaa gcttcttgct tagcagtctc
    11521 ttatctcaat atcgctgctg agaaaatagt tgttcaagga atgggattgg aagaatttcg
    11581 ttaccaagta ctcaatcagc tttcgctcct aagaagagat gaaaattggc tagataccat
    11641 caaaggagag gtttatgaat agagaagcac ttagactata tctggtaacc aatcgctatc
    11701 aagattccgt ggaaagcttt cttgcaaaag ttgagacggc ctgccgttca ggggttacca
    11761 tagtccaatt gcgagaaaaa aatctcacaa ccaatcaata ttatcaactg gcaaaacaag
    11821 tcaaggaaat aacagatgct tatcaggtac ccttgataat cgatgatcgg ttggatgttt
    11881 gtcttgcggt tgatgctgct ggtctgcata ttggagatga cgaactccca gtttcggttg
    11941 cccgacaagt cttgggtcct gaaaaaatcc tcggtgtcac cgctaaaacg gttaaaagag
    12001 ctctggaagc ggagaaatca ggtgcagatt acttgggtac aggagccatt ttcccaacca
    12061 ccaccaagga aaatgcgccc attactctga tatcgacctt gaaaacaatt tgccaaacgg
    12121 ttgccattcc agtagttgct attggaggct tgacttcgga gaatattgat cagcttatgg
    12181 gcactggcat agctggtgta gctgttgtac gtgatttgat gcaagcagaa gatattgagg
    12241 caaaaacgca agccttttta acaaagttgc atgacattct ttcctaatta atactcaatg
    12301 aaaatcaaag agtaaactag aaagctagtc gcaggttgct caaagtactg ccttgaggtt
    12361 ttagataaga ctgacgaagt cagctcaaaa cagtgttttg aggttgcaga tggaagctga
    12421 cgtagtttga agagattttc gaagagtata aaaactctct aattccctta aagtgggaac
    12481 tagagagttt tttttcttaa tctttaaaag ttgtatggtt gactggacca gaaccatgac
    12541 cgagttgagg ggcatcttga atagcttttg tgataaaggc cttggcctta tcaactgcct
    12601 ggtaaagact cttgcccttg gctagttcag cagtaatcac tgcagcaaag gtacatccag
    12661 taccatgggt gtgacaggtt tgaattcgtg ggctttccca gacaaattgt tcattcttgg
    12721 taaagaggaa atctttagca ccacctttga gatgtccgcc tttgataacc acagactgag
    12781 gaccaaattc ttttaaaatc aggcgaccag cacgctgcat gtcttcgggg tcatggattg
    12841 aaaaaccaac aatctcttct gcttcaggaa gatttggcgt aataatagtt gctagaggta
    12901 gtaagtttgt tttgagatag tctctagcac ttgagtcaat caaggcatct ccacttgtag
    12961 caaccataac aggatcaagg acatagggac aatccagttt tttaagatag ggttggatga
    13021 tttccatgat ttcagtagta gccaacattc cagtttttac agcctgaggt ggaatatcag
    13081 aaaagacact gtccaattgg gctttcaaca tttgaggaga aacgtgttcg attagctgaa
    13141 cacctctggt attttgagcg acaagactgg ttacaacagc cattccatag gcatctctcg
    13201 cttggaatga ctttaaatct gccataatgc cagcaccacc actagggtca gtccctgcaa
    13261 tggtcaaagc aacgggtaaa taagtcatct aaaacctccc aaccaactga agtttgtatt
    13321 cttaagaaca agctagtctg ttttagaaag gcaatagaag actgctagtc cccattatca
    13381 tttccacttc catcagctag cattacctag attgagtcag agggatctaa cagtcgttaa
    13441 tctcagcttt acgcacccct agtggttgtt ttcttttttc tttagtatag catattttta
    13501 ttgtttatat agtaatattt gactgcaaat cgtttttcaa atgattaaaa ttctattttt
    13561 cgaagaaaat attatttcta taattgacaa atgtagattt tgagagtata ctgatgagtg
    13621 taattgacaa atgtagattt tggaggtatg gtaatgcaga tttcagatgc agaatggcag
    13681 gtcatgaaga ttatttggat gcagggggag cagaccagta cagatttgat tagggttttg
    13741 gcagagcggt ttgattggtc caagtcaacg gttcagacac ttttgtctcg gctggttgag
    13801 aaagagtgtt tgactcggaa aaaagaaggc aagtcctttg tttattcagc ccttttaact
    13861 ctagaccaaa gtcgggattt acttgtccaa gatatcaaag acaaggtttg ttcccgtagg
    13921 attaggaatt tgttggctga cttgattgta gaatgtgaat ttactcagac tgacttggaa
    13981 gacttggaag ctgtgatttc agagaagaaa tcaagtgctg taacagaagt aagatgtaat
    14041 tgtatgtaaa ggagacgtca tgttaaatag tattgtaacc attatttgta ttgcccttat
    14101 cgcgtttatc ttgttttggt ttttcaaaaa gcctgaaaaa tctggacaaa aagcccagca
    14161 aaaaaatgga taccaagaga ttcgagtgga agtcatggga ggctatactc ctgagttgat
    14221 tgtcctcaag aaatcagtgc cagcacgcat tgtctttgac cgcaaggatc cttcaccatg
    14281 tctggatcaa attgtttttc cagattttgg tgtacatacg aacctgccaa tgggggaaga
    14341 gtatgtagtg gaaatcacgc ctgagcaggc tggagagttt ggctttgctt gtggtatgaa
    14401 catgatgcac ggcaagatga ttgtagagta ggtggagact atgacagaaa ttgtgaaagc
    14461 aagcttagaa aatggcattc aaaaaatccg tatccgagct gaaaaaggct atcatccagc
    14521 ccatatccag cttcaaaagg gaattccagc tgagattacc tttcatcgtg ctactccttc
    14581 aaactgttat aaggaaattc tgtttgaaga agaaggtatc ttggaaccaa tcggcgtaga
    14641 tgaggagaaa gtcattcgtt ttacacctca agaattaggg cgacatgaat tttcttgtgg
    14701 catgaagatg caaaagggaa gctatacagt cgttgagaag actcgaaaat ctctatctct
    14761 cctgcaacgt ttttggatta ctagtatctt tactgtgcct cttgtgattc tcatgattgg
    14821 gatgttgaca ggtagcatta gtcatcaagt catgcattgg ggaacctttc tagcaacaac
    14881 gactattatg ttagttgcag gtaagccata tatccagagt gcttgggcca gttttaaaaa
    14941 gcacaatgcc aacatggata ccttggttgc gctgggaact ctagtggctt atttctatag
    15001 cctagttgct ctctttgctg gtctccctgt ttacttcgaa agtgctggat ttatcctctt
    15061 tttcgttctt ttgggagcag tttttgagga aaaaatgaga aaaaatacgt cccaagctgt
    15121 ggagaaatta ctggacttgc aagctaaaac cgcagaagtc ttgagtgatg atagttatgt
    15181 ccaagttcct ttggaacaag tcaaggtagg cgacctgatt cgagtgcgtc ccggtgaaaa
    15241 gattgctgtt gatggtgtcg tagtagaagg tgtctctagt attgacgaat ccatggtgac
    15301 aggtgagagt ctgcctgtgg acaagacagt tggagatact gtcattggct caaccatcaa
    15361 tcatagtgga acgcttgtct ttagagcaga aaaagttggc tcagagactg ttttggctca
    15421 gattgtggat tttgtgaaga aagctcagac aagtcgtgcg ccgattcaag acttgacgga
    15481 taagatttca gggatttttg tcccagtagt tgtcatttta ggaatcatga ccttttgggt
    15541 ttggttcgtc ttgctcaggg atagtgtggt tgtgcttgga gctagctttg tgtcctctct
    15601 tctctacgga gtggcggttt tgattatcgc ctgtccttgt gccttgggac ttgcaacacc
    15661 gacagccctt atggtgggga caggacgtag tgccaagatg ggggttctcc tcaaaaatgg
    15721 aactgtctta caggaaatcc agaaagttca aacccttgtc tttgataaga ccgggacttt
    15781 gacggaaggg aaacctgtgg taacagatgt catcggcgac gaagtagaag tgtttaggtt
    15841 ggcagcctcc ttggaagatg cttctcaaca cccactggct gaggctatcg ttaagcgagc
    15901 gagtgaagct ggacttgagt ttcaaactgt tgaaaatttt cagaccttgc acgggaaagg
    15961 tgtttcaggg cgaatcaatg gaaaacaagt tttacttgga aatgctaaaa tgctggatgg
    16021 catggatatt tctaatactt atcaagataa actagaagaa ctagaaaaag aagctaagac
    16081 agttgtgttc ttagctgttg acaatgaaat caaaggcttg cttgctttgc aagatattcc
    16141 taaggaaaat gctaagctag ccatcagtca gctaaaaaaa cgtggtctcc gaacagtcat
    16201 gctgacagga gacaatgctg gtgtggcgcg tgctattgca gatcaaatcg gaattgaaga
    16261 ggtcattgca ggcgtcttgc cagaagaaaa agcccatgaa atccataaac tgcaacagtc
    16321 agggaaagta gcctttgttg gggacggtat caatgacgct cctgccctta gtgtagcaga
    16381 tgtggggatt gctatgggag ctggaacaga tatcgccatc gagtcagcag atttggtgtt
    16441 gacaaccaat aatcttttag gagtggttcg tgcctttgat atgagtaaga aaacctttca
    16501 tcgaattcta ctcaatcttt tctgggcttt tatctacaat gttgtcggaa ttccgattgc
    16561 agcaggagtc ttttcaggtg ttggactggc tctcaaccca gaattggcag gtctagccat
    16621 ggcctttagt tctgtatctg ttctgaccag ttcccttctg ttaaatttta gtaaaataga
    16681 ctaaaagtaa tgactagatt tctttgttat aaaacagaaa tgacagaact ttcaaaactg
    16741 tattagaata gagaatagag agttttgagc agatttttag aaaagtcagc ataaatatga
    16801 tacagtggaa tagtaaaaat ttggagaacg tttccaattc tatgtaatcg tattctccaa
    16861 atctaaaaaa attgaaggag agttatcatt atgactcaag ggaaaattac tgcatctgca
    16921 gcaatgctta acgtattgaa aacatggggc gtagatacaa tctacggtat cccatcagga
    16981 acactcagct cattgatgga cgctttggct gaagacaaag atatccgctt cttacaagtt
    17041 cgccacgaag agacaggtgc tcttgcagcg gttatgcaag ctaaattcgg cggctcaatc
    17101 ggggttgcag ttggttcagg tggtccaggt gcgactcact tgattaacgg tgtttacgat
    17161 gcagctatgg ataacactcc attcctagcg atccttggat cacgtccagt taacgaattg
    17221 aacatggatg ctttccaaga gcttaaccaa aacccaatgt acaacggtat cgctgtttac
    17281 aacaaacgtg tagcttacgc tgagcaattg ccaaaagtaa ttgacgaagc ctgccgtgct
    17341 gcaatttcta aaaaaggtcc agctgttgtt gaaattccag taaacttcgg tttccaagaa
    17401 atcgacgaaa actcatacta cggttcaggt tcatacgaac gctcattcat cgctcctgct
    17461 ttgaacgaag ttgaaatcga caaagctgtt gaaatcttga acaatgctga acgcccagtt
    17521 atctatgctg gatttggtgg tgttaaagct ggtgaagtga ttactgaatt gtcacgtaaa
    17581 atcaaagcac caatcatcac aactggtaaa aactttgaag ctttcgaatg gaactatgaa
    17641 ggtttgacag gttctgctta tcgtgttggt tggaaaccag ccaacgaagt ggtctttgaa
    17701 gcagacacag ttcttttcct tggttcaaac ttcccatttg ctgaagttta cgaagcattc
    17761 aagaacactg aaaaattcat ccaagttgat atcgaccctt acaaacttgg taaacgtcat
    17821 gcccttgacg cttcaatcct tggtgatgct ggtcaagcag ctaaagctat ccttgacaaa
    17881 gtaaacccag ttgaatcaac tccatggtgg cgtgcaaacg ttaagaacaa ccaaaactgg
    17941 cgtgattaca tgaacaaact cgaaggtaaa actgagggtg aattgcaatt gtatcaagtt
    18001 tacaatgcaa tcaacaaaca tgctgatcaa gacgctatct actcaatcga cgtaggtaac
    18061 actactcaaa catctactcg tcaccttcac atgacaccta agaacatgtg gcgtacatct
    18121 ccactctttg cgacaatggg tattgccctt cctggtggta tcgctgctaa gaaagacaat
    18181 ccagatcgcc aagtatggaa catcatgggt gatggagcat tcaacatgtg ctacccagac
    18241 gttatcacaa acgttcaata cgaccttcca gttatcaacc ttgtcttctc aaatgctgag
    18301 tacggcttca tcaagaacaa atacgaagat acaaacaaac acttgtttgg tgtagacttc
    18361 acaaacgctg actacgctaa aattgcggaa gctcaaggag ctgttggatt cacagttgac
    18421 cgtatcgaag acatcgatgc agttgttgca gaagctgtta aattgaacaa agaaggtaaa
    18481 actgttgtca tcgatgctcg catcactcaa caccgtccac ttccagtaga agtacttgaa
    18541 ttggatccaa aacttcactc agaagaagct atcaaagcct tcaaggaaaa atacgaagca
    18601 gaagaactcg taccattccg tctcttcttg gaagaagaag gattgcaatc acgcgcaatt
    18661 aaataattcc tctcgccgaa aatcaaatat gaaacttgta gactttattc tttgattttc
    18721 atagagcaga actttaaaag atcggagcaa tccggtcttt ttatggagga gagtaaatga
    18781 atttaaatca attagatatt atcgtttcaa atgttcccca agtctgtgct gacttggagc
    18841 atattttgga taaaaaggca gattatgctg atgatggttt tgctcagttt acgattggta
    18901 gtcactgcct tatgttgtca caaaatcatt tggttccttt ggaaaacttt cagtcaggaa
    18961 tcattattca tatcgaggtt gaggatgtag accagaacta caaacggttg aacgagcttg
    19021 gtataaaggt tttacacgga ccaactgtaa ccgattgggg aacagagtcc ttattagttc
    19081 aaggacctgc tggtctagtg cttgattttt atcgtatgaa ataggtcgcg tagtcatttg
    19141 acgttaacct tagctatttt taaaatagaa attgagaata tgaactattg aaagatcgga
    19201 gcaatccggt ctttttatat aaagaaattg catataatac tcatctgctt tcaaaaagca
    19261 ttctagtcca tctccgatta acgatggact ttatcacctc cttctccaat ccttgtatga
    19321 catcttgaag ttgattcatg acatcttcca aagttcgaaa ggccttattc ttaaatccac
    19381 gtttacgaat ctctttccac acttgttcaa tgggttcatc tctggtgtgt atggaggaat
    19441 aaaggtaaaa ccaatattag tcggaatctt taaggtactt gatttatgcc atatagcatt
    19501 gtccataacg agtaaaagat aatcatctgg ataagcttgt gaaagctctt ctaaaaaggc
    19561 gttcatccac tcagtattac atccaccagc tattaagaaa aatgattcgc ctgtatgggc
    19621 atcaacagct ccataacaat agtgaaattc tcgtatatag tgactatgga catgtggacc
    19681 tactcctatt ggagcccaac aagatcccag tttactgatt ctaccgaaac cagcctcatc
    19741 ttggtacatc aagcgaacct tacgaaaacg tctactgctt ttaaagcgct ttcttttctt
    19801 cttgaattga gattttattt ttagacgcga caatggtttg agcgtctgct ttcctaggat
    19861 gttctggacg tggcataata tttcgccaac catggtgctt caacagttga tagaaggcat
    19921 cacgtgtgta ggaacgacct aactcctttt tataagcctg aaataaggca tcaattgtaa
    19981 caaattctcc tgcctctgta gccttcaaat ggcgggcaag aaagactttc ttttcctcaa
    20041 tcgtcatata tgcatggtta cggccaccac gtgtttcttg aaggagagag tcgagttcga
    20101 actcctcata tttttttaca tttcgccaaa tcgttgtttg attacagtct atagtgtatt
    20161 gaatctataa cagtacacct tagctgctaa aatatttcta taaattagtt tgactttcct
    20221 gatagagttg ttcacatctt atttcaaact actataaaag ttctataatc tctttataag
    20281 atttgcc
//
LOCUS       DBJKQU010000039        20277 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.039, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000039 DBJKQU010000000
VERSION     DBJKQU010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.039"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            158..3259
                     /locus_tag="ACSUUC_001527"
     CDS             158..3259
                     /locus_tag="ACSUUC_001527"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HHQ8054716.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVLEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3342..4349
                     /gene="pfkA"
                     /locus_tag="ACSUUC_001528"
     CDS             3342..4349
                     /gene="pfkA"
                     /locus_tag="ACSUUC_001528"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HHQ8054717.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEADSKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4408..5913
                     /gene="pyk"
                     /locus_tag="ACSUUC_001529"
     CDS             4408..5913
                     /gene="pyk"
                     /locus_tag="ACSUUC_001529"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HHQ8054718.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDETREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6091..6438)
                     /locus_tag="ACSUUC_001530"
     CDS             complement(6091..6438)
                     /locus_tag="ACSUUC_001530"
                     /inference="COORDINATES: protein motif:HMM:NF012798.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHQ8054719.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDKYITIAKTFVEIHLNFLINLC
                     ISYFILNENQRAN"
     gene            complement(6770..6877)
                     /locus_tag="ACSUUC_001531"
                     /pseudo
     CDS             complement(6770..6877)
                     /locus_tag="ACSUUC_001531"
                     /inference="COORDINATES: protein motif:HMM:NF012920.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
     gene            complement(6987..7241)
                     /locus_tag="ACSUUC_001532"
     CDS             complement(6987..7241)
                     /locus_tag="ACSUUC_001532"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HHQ8054720.1"
                     /translation="MGTKIGISKNTIGNYEKRVRSTKKNTIFDLVKVFSSLIDALFSP
                     VQKDSPSDIQSIYDQRAPSRQGKVLTYAERQLYDQKNEVS"
     gene            7677..8549
                     /locus_tag="ACSUUC_001533"
     CDS             7677..8549
                     /locus_tag="ACSUUC_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HHQ8054721.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPTDDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8695..9039)
                     /locus_tag="ACSUUC_001534"
                     /pseudo
     CDS             complement(8695..9039)
                     /locus_tag="ACSUUC_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            9182..9493
                     /locus_tag="ACSUUC_001535"
     CDS             9182..9493
                     /locus_tag="ACSUUC_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054722.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKECEELRQIITTIFEQKMNKHSI
                     K"
     gene            9497..10213
                     /locus_tag="ACSUUC_001536"
     CDS             9497..10213
                     /locus_tag="ACSUUC_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHQ8054723.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEEFICLIGHSLGGDLARYLASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10342..11157)
                     /locus_tag="ACSUUC_001537"
     CDS             complement(10342..11157)
                     /locus_tag="ACSUUC_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family putative permease subunit"
                     /protein_id="HHQ8054724.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQVTNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11154..12059)
                     /locus_tag="ACSUUC_001538"
     CDS             complement(11154..12059)
                     /locus_tag="ACSUUC_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HHQ8054725.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSIVVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSHLSPAKKVFQVFVQAIDEFFDTGRYLVFGCLFASVIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(12060..12191)
                     /locus_tag="ACSUUC_001539"
     CDS             complement(12060..12191)
                     /locus_tag="ACSUUC_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HHQ8054726.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKAKAEKKN"
     gene            12471..14600
                     /locus_tag="ACSUUC_001540"
     CDS             12471..14600
                     /locus_tag="ACSUUC_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HHQ8054727.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLEFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGKKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            14587..15036
                     /locus_tag="ACSUUC_001541"
     CDS             14587..15036
                     /locus_tag="ACSUUC_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HHQ8054728.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            15095..15367
                     /locus_tag="ACSUUC_001542"
     CDS             15095..15367
                     /locus_tag="ACSUUC_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HHQ8054729.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGRFW"
     gene            complement(15721..15912)
                     /locus_tag="ACSUUC_001543"
     CDS             complement(15721..15912)
                     /locus_tag="ACSUUC_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054730.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            16340..17098
                     /locus_tag="ACSUUC_001544"
     CDS             16340..17098
                     /locus_tag="ACSUUC_001544"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054731.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            17100..19088
                     /locus_tag="ACSUUC_001545"
     CDS             17100..19088
                     /locus_tag="ACSUUC_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8054732.1"
                     /translation="MFRLTNKLAVLNLIKNRKLYYPFALAVLLAVTLTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVIITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDNGYKIKEKEVFRYTYFGVANQEGNKLTFFEKGQNRVQPTTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(19130..19804)
                     /locus_tag="ACSUUC_001546"
     CDS             complement(19130..19804)
                     /locus_tag="ACSUUC_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VIT1/CCC1 transporter family protein"
                     /protein_id="HHQ8054733.1"
                     /translation="MDSNFAGRLNILRAGVLGANDGIISIAGVVIGVASATTNIWIIF
                     LSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQN
                     GECKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSEYRIPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLL
                     EQLFSI"
     gene            complement(19746..>20277)
                     /locus_tag="ACSUUC_001547"
     CDS             complement(19746..>20277)
                     /locus_tag="ACSUUC_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HHQ8054734.1"
                     /translation="ENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVV
                     NQALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIR
                     RWLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRNRF
                     KFCRSFKYPARRCSWC"
BASE COUNT         6207 a         3699 c         4279 g         6092 t
ORIGIN      
        1 ctatttttat atataatata gtataaatat aaaaatgatg acaaaaatac aaatggatag
       61 aaaataaatt agtaagctga tgaaattttt ctcaagagaa gccatttata ggtgaaaatg
      121 gtataatata gtgagaagga tagaggagaa gtgtaaattg atcgcacaac tagatacaaa
      181 aacagtctat agttttatgg aaagcgtcat ttcgatcgaa aagtatgtga gagcagctaa
      241 agaatacggc tacactcatt tggctatgat ggatattgac aatctttatg gcgctttcga
      301 ctttctagag attacaaaaa aatacggcat tcatcctttg ctagggcttg aaatgacagt
      361 gtttgtagat gatcaggaag tgaatttgcg ctttttagct ctatctagtg tgggctatca
      421 gcagttgatg aagctttcga cagccaagat gcagggggag aaaacttggt cagtcctgtc
      481 ccagtacctg gaggatatcg cggtcattgt gccttatttt gatagagttg agtcgttaga
      541 actaggctgt gattactata taggggttta tccagaaaca ctagcaagcg aatttcatca
      601 tcctatctta cctctttatc gggtcaacgc ttttgaaagc agggatagag aagttcttca
      661 agttttaaca gcgattaaag aaaatctacc gctcagagaa gttcccttgc gttcgagaca
      721 agatgtcttt atatcagcaa gttctttaga gaaactattc caagagcgtt ttccgcaagc
      781 tttggacaat ttagaaaagc ttatttcagg catttcttac gacttggata ctagtctgaa
      841 actgcctcgt tttaatccag ctagaccagc agtagaggag ttgagagagc gtgctgaact
      901 ggggcttgtt cagaaggggt tgactagtaa agaatatcaa gatagactag accaagaatt
      961 gtctgttatt catgatatgg gctttgatga ttatttcttg gttgtttggg atttgttgcg
     1021 ttttggacga tcgaatggct attatatggg aatgggaagg ggttctgcag taggcagttt
     1081 ggtttcttat gccttagaca tcacggggat tgacccagta gagaaaaatc tgatttttga
     1141 acgctttctt aatcgtgaac gctataccat gcctgatatt gatattgata tcccagatat
     1201 ttatcgtcca gattttatca gatatgttgg taataaatat ggtagtaaac atgcggcaca
     1261 aatcgttact ttttcaacct ttggagccaa gcaagctctt cgagatgtct tgaaacgctt
     1321 tggtgtgcca gagtatgaat tatctgcaat tactaagaaa atcagttttc gtgacaatct
     1381 taagtcggcc tatgagggca atctccagtt tcgtcagcaa atcaatagta agttagaata
     1441 ccaaaaagct tttgagattg cttgcaagat agagggctat ccaaggcaaa cctctgtcca
     1501 tgcggctggt gttgtaatta gtgaccaaga tttaaccaac tacattcctc taaagtatgg
     1561 tgatgaaatt ccactgactc agtatgatgc tcatggagtt gaggctagcg gacttttgaa
     1621 gatggacttt ctgggactac gaaatttgac ctttgtccag aagatgcaag agttgcttgc
     1681 tgaaacagaa ggtattcatc tgaaaattga agaaatcgat ttagaagaca aagaaacgtt
     1741 agctttattt gcctctggta atacaaaagg tatctttcaa tttgagcaac caggtgccat
     1801 tcgtctgctt aagcgtgtgc aaccagtctg ttttgaagat gtcgtcgcga ctacttctct
     1861 aaatcgaccg ggtgctagtg actatatcaa taattttgtg gcaagaaagc atgggcagga
     1921 agaagtgact gttctggatc cagtactgga ggatattttg gctccaacct acggcataat
     1981 gctctatcag gagcaggtta tgcaggttgc ccagcgattt gctggattta gtcttgggaa
     2041 ggccgatatt ttgcgtcgag ctatgggtaa aaaggatgct tctgctatgc atgagatgag
     2101 ggcttccttt attcaaggct ccatagaagc aggccatact gcggaaaaag cagagcaggt
     2161 ttttgatgtt ctggagaagt ttgcaggcta tggttttaac aggtcacacg cctacgccta
     2221 ctcagccttg gccttccagt tggcttattt taaaacacat tatccagcca tattttatca
     2281 gattatgttg aattctgcta acagtgatta tgtaacagat gccttagaag caggttttga
     2341 agtagcccca ttgtccatca acacgattcc ctatcacgat aaaattgcca acaaggccat
     2401 ctatctaggt ttgaaatcca ttaaaggagt cagtaatgat ttagctctct ggattattga
     2461 acatagacct tattctaaca ttgaagattt tatagctaaa ttacctgaga attatctgaa
     2521 acttcctctg ctagaacctt tggtaaaagt tggtcttttc gattcatttg aaaaaaatcg
     2581 tcaaaaagta tttaataact tagctaatct atttgaattt gtgaaagagt tgggaagttt
     2641 gtttggagat gctatttata gttggcagga atcggaagat tggacggaac aagaaaaatt
     2701 ttatatggaa caagagcttt tagggatagg tgtcagcaaa catccactac aagctattgc
     2761 aagtaaggct atttacccga ttaccccaat cggaaatttg tcagaaaata gctatgctat
     2821 tattttggtt gaagttcaga aaataaaagt gattcgtacc aaaaagggtg aaaatatggc
     2881 cttcttacag gcagatgata gtaagaaaaa attggatgtc actctctttt cagacttata
     2941 tcgtcaggtt ggacaggaaa taaaagaggg agccttctac tatgtaaaag gaaaaataca
     3001 atcacgtgat ggccgtctgc aaatgattgc acaagaaata agagaagcag ttgctgaacg
     3061 cttttggata caggtgaaaa atcatgaatc ggatcaagaa atttcacgta ttttagaaca
     3121 atttaaaggc ccaatcccag tcatcatccg gtatgaagag gaacagaaaa ccatcgtttc
     3181 tccccatcat tttgtagcta aatccaatga attagaggag aaattgaatg aaatcgttat
     3241 gaaaacgatt tatcgctaaa aatacggaaa atagaagaat tttaaaatca aatgtgatat
     3301 aatcaagaag aatgttaaaa gaaaaaggag cataaaccaa tatgaaacgt attgctgttt
     3361 tgactagtgg cggagacgca cctggtatga acgctgctat ccgtgcagtt gttcgtcaag
     3421 caatttcaga aggaatggaa gtgtttggta tctatgacgg atatgctggt atggttgccg
     3481 gtgaaattca tcccctagat gcagcttcag taggagacat catttctcgt ggtggtactt
     3541 ttcttcactc agctcgttat ccagagttcg ctcaacttga agggcaactt aaagggattg
     3601 agcaattgaa aaaacacgga attgaaggtg tagttgttat cggtggtgac ggatcttacc
     3661 acggcgctat gcgtttgact gaacatggct tcccagctat tggtcttcca ggtacaatcg
     3721 ataacgatat cgttggtact gactttacaa tcggttttga cacagcggtt actactgcca
     3781 tggacgctat tgataagatt cgtgatacat catcaagtca ccgtcgtact tttgtaatcg
     3841 aagttatggg acgtaacgct ggtgatatcg ctctttgggc tggtattgca actggtgctg
     3901 atgaaatcat catccctgaa gcagactcca agatggaaga tatcgtagca agcatcaaag
     3961 ctggttatga atgtggtaaa aaacacaata tcatcgtctt agctgaaggt gtgatgtcag
     4021 cggctgaatt tggtcaaaaa cttaaagaag ctggagatac aagcgacctt cgtgtaacag
     4081 aacttggaca tattcaacgt ggtggttctc caactgcgcg tgaccgtgtt ttggcgtcac
     4141 gtatgggtgc acatgctgtt aaacttctta aagaaggtat cggtggtgtt gcggttggta
     4201 ttcgtaacga aaaaatggtt gaaaatccaa ttcttggtac tgcagaagaa ggggcattgt
     4261 ttagccttac tgcagaaggt aagattgtgg ttaacaaccc acacaaagcc gatattgagc
     4321 tatctagctt gaataagagc ttgtcataat ttacaattta gttaataaga ccaaaaaggt
     4381 catatatata aaggagtcac aaaaatcatg aacaaacgtg taaaaatcgt tgcaactttg
     4441 ggtcctgcgg tagaaatccg tggtggtaaa aaattcggtg aggacggata ctggggtgaa
     4501 aaacttgatg ttgaagcttc agctaaaaac attgctaaat tgattgaagc tggtgctaac
     4561 acattccgat tcaacttctc acacggcgac caccaagaac aaggtgagcg tatggcaact
     4621 gttaaacttg cggaaaaaat tgcaggtaaa aaagttggtt tccttcttga tacaaaagga
     4681 cctgaaatcc gtacagaatt gttcgaaggt gaagctaaag aatattcata caaaactggt
     4741 gaaaaaattc gtgttgcaac taaacaagga atcaaatcaa ctcgtgaagt gattgcgttg
     4801 aacgttgctg gtgctcttga tatctatgat gatgttgaag ttggtcgtca agttttggtt
     4861 gacgatggta aacttggtct tcgtgtggtt gctaaagatg atgaaactcg tgaatttgaa
     4921 gttgaagttg aaaacgatgg tatcatcgct aaacaaaaag gtgtgaacat ccctaacact
     4981 aaaattcctt tcccagctct tgctgaacgc gataacgacg atatccgttt cggtcttgaa
     5041 caaggtatca acttcatcgc aatttcattc gtacgtactg caaaagatgt gaacgaagtt
     5101 cgtgcaatct gtgaagaaac tggaaacgga catgttcaat tgttcgctaa aatcgaaaac
     5161 caacaaggta tcgataactt agacgaaatc atcgaagcag ctgatggtat tatgattgct
     5221 cgtggtgata tgggtatcga agtaccgttc gaaatggttc cagtttatca aaaaatgatt
     5281 atcaagaaag tcaatgctgc aggtaaagtt gttatcactg caacaaacat gcttgaaaca
     5341 atgactgaaa aaccacgtgc aactcgttca gaagtatcag acgtattcaa cgctgttatc
     5401 gacggaactg acgctacaat gctgtcaggc gagtctgcaa acggtaaata cccactcgag
     5461 tcagtaacta caatggctac aatcgacaag aacgctcaag ctcttcttaa tgaatacgga
     5521 cgtcttgatt cagattcatt tgagcgtaac tctaagacag aagtaatggc ttctgctgtt
     5581 aaagatgcta ctagctcaat ggatatcaaa ttggttgtaa ctcttactaa gacaggtcat
     5641 actgcacgtt tgatttctaa ataccgtcca aatgctgaca tcttagcatt gacatttgac
     5701 gaattgacag aacgtggctt gatgttgaac tggggtgtta tcccaatgtt gacagatgct
     5761 ccatcttcaa ctgacgatat gttcgaaatc gctgaacgta aagcggtaga agcaggtctc
     5821 gttgagtcag gcgatgatat cgttatcgtt gctggtgtgc cagtaggaga agctgttcgc
     5881 acaaacacaa tgcgtatccg cacagtacgt taagaaaaat ataaaaacct atcatatcca
     5941 gctttctagt ctgtatgatg ggctcttttt ttgtccaggg gggcaaaaag ggggcaaaac
     6001 tttcataatg gattgatact cttcgaaaat caaattcaaa ccacgtcagc gtcgccttac
     6061 cgtactcaag tacagcttgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
     6121 gaaataagat atgcacaaat tgattaggaa attcaaatga atttctacaa atgttttagc
     6181 aatcgtaatg tacttgtcta gattcgatct gatatatttt cgatttaatg atatggtatt
     6241 taaaacctcc aaagtagctt gctccattct tttacttacg tgagtgtaga tgttatttac
     6301 tgttttagcg tttttgtgtt ccactctaac cattatagca ttcttctcag ctagtgtact
     6361 aaggagtgtg tgcctgaaaa tatgggaact aaggggctgg tttatcggtt tctctagttt
     6421 agtatttgcc ttttgcaaag tgatgttaaa tgcctttctc taaatttaca tatcactatt
     6481 gtttaacaaa atctaatcta ctttaggtca cttattcttt ttttgaaatg tagaatgaac
     6541 tttttcaaag tttttcgaat cttttaaaat ctgtttgttt tatatcgcca ttctccccct
     6601 tttttaattc tccctatata gcctgacaac tttcccgatg gtacgaatat ggttgctttc
     6661 gtctaggtgg atgtcggggt atttgggatt gagttttttt aaggtagcct tggcggagtt
     6721 tcttgacata gttagcgccg tctacttgga agatgccgat ggtattatag tcaatctgtg
     6781 gggtattctt gataaatagg tagtcgctgt ttcttatctt tggctccatg gacttgctga
     6841 tgacataagc gattgggtcg tagtcgtctg ggataatgga aactccatat ctaaatcgtt
     6901 gtcctgcatc gagcggctac ctgcagagat aaactatcta acacgagagt aagtagtctg
     6961 tctgtagtcg tccagtctga tgatttttac gatacttcgt ttttctgatc atacagttgc
     7021 ctctcggcat aggtcagaac tttaccttgt ctggatggtg cccgttggtc gtagatagat
     7081 tggatatcgc taggagaatc cttttgaact ggagaaaaga gggcatcaat caagctactg
     7141 aatactttaa ctaagtcaaa tatagtattt ttcttagtag acctaaccct tttttcataa
     7201 tttccaatgg tgtttttact tataccaatc ttagtaccca attcttattg agttcaacca
     7261 ttactagtct atattgtttt atagttgatt gagtttggaa tagtacgctg tagctgctaa
     7321 aacatttcta ggaattaatt tgcctttcct aatagagttg ttcatatctt atttcaatct
     7381 actatatttt tcgcctctaa caatcgcaat ctcttcttta tctacgaacg aaatcgcttt
     7441 ctatttttgt aagtaaagca tcacacgaaa tccacgaaaa tgaaaacctt tgttgtgttt
     7501 tcgtaaaaaa tttgttgaca gagcacgaaa cgcctactat aattaaatca agcttaagga
     7561 aataacaaaa aaacaaatcg gagggaaaga cgatgaacac attaaatgag aaagtaatca
     7621 atatctgtaa agcaatagtt aaagaaactt taatccaaga catttaggag aaagaaatga
     7681 agaaatcaag aaaattagcc acattaggaa tctgttcagc tttgttttta ggcttggctg
     7741 cttgtcaaca acaacatgct acttctgagg ggacgaatca aaggcaaagc agttcagcga
     7801 aagttccatg gaaagcttca tacaccaacc taaacaacca ggtaagtaca gaagaggtca
     7861 aatctctctt atcagctcac ttggatccaa atagtgttga tgcatttttt aatctcgtta
     7921 atgactataa tactattgtc ggctcaactg gcttatcagg agatttcact tcctttactc
     7981 acaccgaata cgatgttgag aaaatcagtc atctctggaa tcaaaagaag ggcgatttcg
     8041 ttgggaccaa ctgccgtatc aatagttatt gtcttttgaa aaattcagtc accattccaa
     8101 agcttgaaaa gaatgaccag ttgcttttcc tagataatga tgcgattgat aaaggaaagg
     8161 tctttgattc acaagataag gaagagtttg atattctatt ttcgagagtt ccaactgagg
     8221 caactacaga tgtcaaggtt cacgctgaaa agatggaaac attcttctca caatttcaat
     8281 tcaatgaaaa agctcgaatg ctgtctgtag tcttgcacga caatctggat ggcgagtatc
     8341 tgtttgtagg ccacgttggg gtcttagtac ctactgatga cggtttctta tttgtagaga
     8401 aattgacttt cgaagagccc taccaagcga ttaaatttgc tagtaaggaa gattgctaca
     8461 agtatttagg caccaagtat gcggattata caggcgaggg actggctaag ccttttatca
     8521 tggataatga taagtgggtt aaactttaat agtgttatga tatgacagta atcttaggat
     8581 ttttatttct atttttgatg agttggtggg ttatttcaat cgttaatagc cagaaaccac
     8641 gcaaaaatga aacatttatt ggctatatcc aaagatacga tattgatggg aatggctatc
     8701 aatcattacc gtgtcctcag aactgagagg agttcttgaa atcgtaaaac tactttgaac
     8761 aagagttact tcaacccatt ggatccgacg gagtaagttg ctttcgtgga taccaaaaac
     8821 agccgcaatt tcttcataag tgcggtattc tcgcacatat tgaagagtgg ccataagaag
     8881 gtcttctagg cttaatttag gttttcgtcc cccttttgtg tgtttaagtt gataagctgt
     8941 ttttaataca gctaatatct cttcaaaagt ggtgcgctga acaccaacaa gacatttaaa
     9001 tcgtgcatca gttagttgtt tacttgcttc ataattcata gaactactat accatatttt
     9061 gtttcgcagg aagtctaatg ctaaaatctt atcagtgaga agatttctta aagtttattc
     9121 tttgtaattt catctgtatt agtacataat ttaacttaga gaaaatagga ggactaatcg
     9181 aatggaatta aaagatttta cagaaaaaga acaggaaatg attaagaaaa ggcttacaat
     9241 gtctaatatt agtgacaaag aaactactga gaagattctg gcgctagtac cacaagactt
     9301 gattaagcga atcccgtttt ttgtcagaaa acatgctaca acacgtacga ttaaacgcat
     9361 ttcaattgaa caccctgaac tctacgctgt agctcaaaca agtggtgaga ttccagaaaa
     9421 agaatgcgaa gaattgcgtc agattatcac aactatcttt gaacaaaaga tgaataagca
     9481 tagtattaag tagagaatga aaaaatattt tattggcggt ttgggaagca atgcctatca
     9541 tagcaaggat tttcttcaag aactagattc gcaggtctat tttctaaatc catatgaaaa
     9601 gcatcttcga gatgaaacag aattgaaatc atggtttaaa aatgagattg tagaggaaga
     9661 atttatctgt ctgataggtc attctcttgg aggagattta gctcgttatc tcgcatcgga
     9721 atttgaagaa gtaaagaaac tgattctttt ggatggtggc tatctagatt tagataagat
     9781 tttacctttg gatacagagt tagaggaaac taaaaattat atcaaatctc aaattgtttt
     9841 ggacttagat gttcttactt ctaaagaaaa atctgaagca aagcattggt cagaaaatat
     9901 ggagaaagct gtaagacagt cctatcactg gaatgttgag tataatagat atgagttggc
     9961 tataaattat gaaaatatag aagcgatact ccgcctacgg agaaaaatac aagcttttaa
    10021 gagagaagtg ggagatacct tgtttattag tcctcgctat cctaatgaag ctacatggag
    10081 agaggaagcc ctaaaagaat tgccagacta ttttgatact atttttttag aaaactttgg
    10141 ccatgagctt tatactcaag cacctaaaga aatcgctagt ctaatgaatg agtggctcgc
    10201 ttattttcta tgagctactt gtattgctgg aaatggtata agatgaaaat ctacaagtca
    10261 ctaattttca tataacaaaa aacgaacagg ctctttttct gttattcaga agagaacttg
    10321 ttcgttttta tcttgatttt cttaaaaagc tctatataca tagggatttt ctggtttatc
    10381 gactttggta aagctgtcga tttccaaggt tggaaggttt tgtttgagtt ctttatggta
    10441 gtgattgacc agttttcctt tggctgttat ccaagtgttg ttttcatact gccgggtatt
    10501 gcccttggtc agcaatccat agacaccaga atctgcgata cagtggataa tgccgaatcg
    10561 gaacagaaat tgactattgg catgactggg gtcgttatag acaaagcctg taaactggat
    10621 tgtcttgccc tcaaactcat ctggatagtc gtagatagcc tccatgactt ccatatagtt
    10681 ttcattagtg acctgaatac tatcttggga taagtattta tccgccgccg ttcgcatttc
    10741 cttttcatag gctgattttg aaaaataaga actggtatct ggtttcaaat attggcttgt
    10801 cgtcccttcg cttgtctgaa tggctagatc cgttccttcc gataggggga aatgataacc
    10861 tttagcagaa acagtctgag aatccaagct aacagttggg aaagttaagc cgatgacaag
    10921 tggaatagcc agaagagaaa tactcgtcat cttggctaat cggctgttca gatgactgtg
    10981 ggttttgact tgcttcatcc agatatacaa ttgaacgata gccaagataa aagaaagcac
    11041 catggagata taggccagat aggaatagtg catgttgatg tactggttta gtttgcccga
    11101 cagatggagg taaatagtca gttcaaaata gccagctaaa actaaaaatc gaatcatagg
    11161 atgactccaa tcaagagaga ataggctaaa acgaccagag tcacaatcgt aatgaagtga
    11221 ctaataaatc gtgctttcaa gtaatttttc atcataagaa tatttttgat atccagcatt
    11281 gggccaatga cgagaaaagc cagaactgga gccaaaccga aactcgagag tagagaagcc
    11341 ccgataaagg catccgcctc actacagagc gaaagaagaa aggccaaaat catcaagagc
    11401 aggatggcaa aaagaggagt cgcactgata gaggtcagaa tccgagtcgg aacataaacc
    11461 tgtataacag aggcaaagag acagccaaat accaaataac gtcccgtatc aaaaaactca
    11521 tcaatggctt gcacaaagac ctgaaaaact ttttttgcag gacttaagtg agaaaaatca
    11581 tgctcatgac aggctagacg attttctttt tgaatcggtt cttgccagaa aaatcctaga
    11641 aaaattccta gtattacagc cacaacgatg gaacccagag ctcgtaatag ggcgacatgg
    11701 aaggagttgc caaaggcaga ataggtcgca aaaagaacaa tgggattgat aacaggtgct
    11761 gtcacaagaa aaggaacggc cgtgtaactt ggaacctttt tttccagaaa acgattgatg
    11821 atggggacga ttccacattc acaggaaggg aaaagtatac cgacaaaggt cccaaaaaag
    11881 attctccccc aacgatttcg agggagaaaa tgataaacct tgtcaggtgt gatataaact
    11941 tcaatcagcc ctgagacaat acttcctatc agaacgaagg gaagggcttc aatgataatg
    12001 gagagaaaaa tggctccagt ttgaagtaca ctagatggga gttgttgaaa agcagtcatc
    12061 tagtttttct tttctgcttt ggcttttttc tctttgtcat cagggaaagt gacttgtttc
    12121 aaatcaggga gtttagcaaa ctcttcaaac atcttgtcca agtcgtctcg ttttgtaaat
    12181 ttgacagcca taggtgtacc tcgattctaa attctacctc tattatacta ttattttgcg
    12241 gaaaagggag ttttttaatt tgttttcgat agttgatact cttcgaaaat ctcttcaaac
    12301 cacgtcagct tcgccttacc gtagtacggt tactgacttc gtcagttcta tccacaacct
    12361 caaaacagta ttttgagcag cctacggcta gcttcctagt ttgctttttg atttttattg
    12421 agtatgaaaa ggattggaga aagccttcca gcttgtggta taatagattt atggataaaa
    12481 aatatgaaaa aatctctcag gatttgggag tgacgttaaa gcaaattgat accgttctaa
    12541 gtttgacagc tgaaggggcg actattccct ttatcgcgcg ttatcgcaag gacatgactg
    12601 gtagtctgga tgaggtggcg attaaggcta ttattgattt ggataaaagt ctgacaaatc
    12661 tcaatgaccg taaggaagct gtcttagcta agattcaaga acaaggtaag ttgaccaagg
    12721 aattggaaga agctatctta gttgccgaaa aattagcaga cgttgaagaa ctctatcttc
    12781 cttataagga aaagcgtcgt accaaggcaa ccattgcccg tgaagctgga ctctttcctc
    12841 ttgctcgctt gattttgcag aatatagttg acttagagaa agaagctgaa aagttcgtct
    12901 gtgaaggatt tgcgactggc aaggaagcct tgaccggtgc agttgatatt ttggtcgaag
    12961 ccttatcgga agatgtgacc ttgcgttcta tgacttatca ggaagtgctg agacactcta
    13021 aactcacttc tcaagccaag gatgaaagtc ttgatgaaaa gcaggttttt cagatttatt
    13081 atgatttttc agagacagtt ggaactatgc aaggctatcg taccttggct ctcaatcgtg
    13141 gggagaaact tggtgtcttg aagatcggtt ttgaacatgc gacggaccgt attcttgcct
    13201 tctttgctac tcgtttcaag gtgaaaaatg cttatattga tgaagttgtt cagcaatccg
    13261 ttaagaaaaa ggtcttgcct gctattgagc gtcgtattcg gacagaatta actgagaaag
    13321 ctgaagaggg agctatccaa cttttttctg acaatctgcg caatctcctc ttggttgctc
    13381 cactgaaagg gcgcgtggtt cttgagtttg acccagcctt tcgtacaggt gccaagctag
    13441 ctgtcgtgga tgcaacagga aaaatgctga caactcaggt tatttatcct gttaaaccag
    13501 catcagctcg tcaaatcgaa gaagccaaga aagatttagc agatttaatt ggtcaatacg
    13561 gtgtagagat tattgccatt ggaaatggaa cggccagtcg tgaaagtgaa gcttttgtag
    13621 cggaagttct gaaagatttc cctgaagtca gctatgttat cgttaatgaa agtggtgctt
    13681 ctgtctattc tgccagcgaa cttgctcgtc aggagtttcc agacttgacc gttgaaaaac
    13741 gctctgccat ttctatcgcc cgtcgtttgc aagatcctct tgcggaattg gtcaaaatcg
    13801 atcctaagtc aattggtgtc ggtcaatacc aacacgatgt cagtcagaag aaactctctg
    13861 agagtctgga ctttgttgtc gatacagtgg ttaaccaagt tggtgtcaat gtcaatacag
    13921 ctagcccagc tcttctttca cacgtagctg gactcaataa aaccatttct gaaaatatcg
    13981 tcaaataccg tgaggaagag ggaaaaatca cttcacgctc ccaaatcaag aaagttcctc
    14041 gtttgggggc caaggctttt gaacaggctg ctggtttcct ccgtatccct gaaagtagca
    14101 atatccttga taatacagga gttcatccag aaaattacgc tgccgttaag gaactcttca
    14161 aatgcttgga cattaaggat ctgaatgaag aggcccaaag caaactcaag tcgctttcag
    14221 tcaaggaaat ggcgcaagag ttagaccttg gtccagaaac tcttaaagat atcattgcag
    14281 atcttctcaa accaggtcga gatttccgtg attcctttga tgctccagtt ctccgtcaag
    14341 atgtcctaga tatcaaggac ttagtggttg gaaaaaagct agaaggagtg gtgcgtaacg
    14401 ttgttgattt cggtgctttt gttgatatcg gaattcatga ggacggtctc atccatattt
    14461 cccatatgag tcgcaagttt atcaaacacc ctagtcaagt ggtggcagtt ggagatttgg
    14521 tgagcgtttg ggttaagaaa attgatactg aacgtgaaaa agttaatctg tctctcctag
    14581 ctccaaatga aactgactga ttacgtcaag caggtttcac tagaagactt cggcagacct
    14641 tttatccatc atgtccagtg gaataggcgt ctacgttcga caggtgggcg atttttcccc
    14701 aaagatgggc atttggattt taatcccaag gtttatcagg aactggggtt ggacgttttt
    14761 aggaaaattg tccgacatga actctgtcat tatcaccttt atttccaagg gaagggctat
    14821 caacacaagg atcgggattt taaggaactt ttgaaagcag tggatggatt acggtttgta
    14881 ccatccttgc ccaatagtaa ctctaaacca ctcaagcttt atcgttgtca atcctgccag
    14941 caaaggtatc agcgcaagcg taggattgat accaaacgct atcgctgtgg actttgtcga
    15001 ggtaaattgc ttctgataaa tcagcctgag gactgatgaa agccgagcct ccccgtgata
    15061 tactatgtct aacctagcag aaagaggaaa tatcatgaac agtaaatttt ataaaatgag
    15121 acgcaatcgc atgatttcag gagttctggc aggtctgtca gacaagtgga attttgatgt
    15181 taccctagtt cgtttcttgt ttgccatttt tacagttgca aactttggac ttggcgtgat
    15241 tatctatatc atcctagctt ctatcatgcc taccaaggaa gaaatcgaag cagaaatgta
    15301 cggaacaggc ccacgtaaac gcaaagaagc ccaagccatt gacgacaatg aaggcaggtt
    15361 ttggtgaggt tctacagaag atttggaata agcaaaaagc tttaaatcaa tagtctaaac
    15421 tgcttgattt aaagcttttt tacttttata ctcaataaaa atcaaagtgc aaactaggaa
    15481 gccagccaca ggctgtaatt tagtcggcaa tgtgaagttg acatagtttg cactttgatt
    15541 tttgaatagt attaataata tttcgccagc ttcatccaca aactatagtg gattggaact
    15601 agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgacta tcctgatcga
    15661 tttgtcctgt tcttatttca ttttattata aaagcagtaa tttaaactca gttttttaat
    15721 ctatttttgc tgctgagaca atacattttt ggaaaaatgg tggatgctga taacaactga
    15781 taaccagcaa ataacataag cagtgccggt aaattctgta ccgataaagt gtgtgtgttc
    15841 aactaagagc tgaccgatga atggagagag cagatagaga agtccgatga gtatatgttc
    15901 tttgtgtttc attaaagcgc accttctttc cttataggtt gaacgacttg caagtgttaa
    15961 attgaatggt atgttatcta ggtaacctta ctaaaatgtt agttcccgct tcctcctttt
    16021 caaagtaagc cttttcacac ttatatttta caactttaaa aataggaaat caaatcattt
    16081 tctaagtaat tttgcttata tttcacccaa tcttacaaaa atgtaagatt aaagtctctt
    16141 ttgtaaggtt aggttatggc aagcggtctt tttttgatgt aaactagact cataaagaac
    16201 aaaggagtaa catcatgaaa caaatcttac ataagaaaac tagaaaacca agtcacaaag
    16261 aaattgagcg cgttcagctg ggatgcacta tgatgcaagc tacatttcat ttgatgggat
    16321 attaagaaag gagattctca tgacactttt agatgtaaaa cacgttcaaa aaatttataa
    16381 aacacgtttt cagggcaacc aagtagaagc cctcaaggat attcacttta ccgtcgaaaa
    16441 gggtgactac gttgccatca tgggtgagtc tggttctggt aaatcaactc ttctcaatat
    16501 tctagctatg ctggataaac caagtcgtgg tcaggtttac ttgaatggaa ctgacaccgc
    16561 aaccattaaa aattcacagg cctctagctt ccgtcgtgaa aagttgggct ttgtcttcca
    16621 agactttaac ttgctagata ctctatctgt aaaggacaat atcttgcttc cgcttgtctt
    16681 gtcaagaaga cctattacag agatgatgaa gaaattggtg gtgacagctg agaatctggg
    16741 aataaaccaa ttacaagaga agtaccctta cgagatttct ggtggccaga aacagcgtgt
    16801 agcagtagca cgcgccatca tcactgaacc tgaaattctc cttgcggacg aaccgacagg
    16861 agctcttgac tccaagtcat ctgcagcctt acttgatgtc tttgatgaaa tcaatgagcg
    16921 cggccaaacc attctcatgg taacccactc aacagcagca gctagcagag ctaaacgtgt
    16981 actctttatc aaagacggca ttctttacaa tcaaatctac cgtggagaga agacagaacg
    17041 tcagatgttc caagaaatct ctgatacctt gactgtcatg gcaagcgagg tgaattagta
    17101 tgtttcgatt aaccaataag ttagcggtat tgaacttgat taaaaaccgc aaactctact
    17161 atccttttgc gctggctgtt ctcttggcag tcactctcac ctatctcttt tactctctaa
    17221 ccttcaatcc taagattgcg gaaatccgtg gaggaacaac cattcaggct acacttggat
    17281 ttggtatgtt tgtcgtcacc cttgcgtcag ccattatcgt tctctatgcc aatagttttg
    17341 tcatgaagaa ccgttccaag gaactaggaa tttatggcat gttgggcttg gagaagcgtc
    17401 atcttatcag tatgaccttt aaggagttag tggtatttgg gattctaact gttggagcgg
    17461 gtatcggtat tggagccttg tttgacaagt taattttcgc tttcctgctc aaactaatga
    17521 aattgaaggt tgagctggtt gctaccttcc agacgaaagt tatcattaca gtgcttgttg
    17581 tcttcggttt gattttccta ggcctcatgt tcctgaatgc ccttcgaatc gcccgtatga
    17641 atgccctcca gctctctcgt gagaaagcta gtggagagaa aaaaggtcgc ttccttcctc
    17701 tccaaaccat tcttggttcc ataagtttag gaattggcta ttatcttgcc cttacggtaa
    17761 aagatcctct tacagcctta acaaccttct tcatagctgt tttactggtt atctttggga
    17821 cttatctctt gtttaatgca gggattaccg ttttcctcca aatcttaaag aaaaataaga
    17881 aatactatta ccaaccaaat aacctcatat ctgtttctaa cttgattttc cgtatgaaga
    17941 aaaatgcagt tggactagca actatcgcta ttttgtcaac aatggttttg gtaaccatgt
    18001 cagcagcgac aagcattttc aattccgcag aatcctttaa aaaagttcta aatcctcatg
    18061 attttggggt ttcaggacaa aatgttgaaa aagaagattt ggacaaactc ttgagccagt
    18121 ttgcaagtga caatggttat aagattaaag aaaaagaagt gtttcgttac acttactttg
    18181 gtgttgcgaa ccaagaagga aataagttaa ccttttttga aaaaggacaa aatcgtgtcc
    18241 aacccacaac agttttcatg gtatttgacc aaaaagatta tgaaaatatg actggtcaaa
    18301 aactgtctct atcaggaaat gaggtcggtc tctttgccaa aaatgacgga ctgaaaggac
    18361 agaaagctct aactctaaat gatcatcaat tttctgtcaa agaagaattt aataaagatt
    18421 tcattgtcaa ccatgttcca aataagttta atatcttgac tactgattac aattaccttg
    18481 ttgttcctga tttacaagcc tttttggatc aattcccaga ttcggctatc tataatcagt
    18541 tttacggtgg tatgaatgta gatgccagcg aagaagaaca actcaaggtc gctgaggagt
    18601 atgaaaacta cctcaatcaa tttaatgctc aattagacac agaaggtagc tatgtttatg
    18661 gtagcaatct agcagatgct agttctcaga tgagtgccct ctttggtggt gtcttcttta
    18721 tcggtatttt cctatccatt atctttatgg tcggaactgt tctggtcatc tactacaaac
    18781 aaatttctga aggctacgaa gaccgtgaac gctttattat cttgcagaaa gtcggtttgg
    18841 accaaaagca aatcaagcaa accatcaaca aacaggtttt aactgttttc ttccttcctt
    18901 tgctctttgc cttcatacat ctcgcctttg cctaccatat gcttagcctg attttaaaag
    18961 tgattggtgt actggatacg actatgatgt tgattgtgac cttgtctatc tgcgctatct
    19021 tcctcatcgc ctatgtgctg attttcatga ttacttcaag aagttatcgc aagattgtgc
    19081 aaatgtaaaa aagatacctc gacttcaaaa tcgaggtatt tcttgtattc taaatgctga
    19141 aaagttgttc gagcaggaag gtaactccca tggtcaagag accaatagca aggttccgaa
    19201 tcatagctgt tctagtcgga tcctttccaa gtctggcact agtgtaacca gtgagaagaa
    19261 gggccacacc gacaataagg acagtagcag ggatgcgata ttcacttggg aatatggtca
    19321 ctgacagcat tggaggcaaa cttctaagga aaaaggcaac gaagctagaa atggcagcgt
    19381 gccaaggatt ggtaaattct tcatactcaa tcccatattt ttcctctacc agagccttga
    19441 gtggattttt aagaaagatc ttattggtca agagttgggc agaagttttg cattctccat
    19501 tttggatata agcagcatag agggattttt tggctagttc cctatcttgg tctaacaaga
    19561 gtttttctcg cgaaacggca gcttcctcgg tatcttttgg agttgaaacg gatacatatt
    19621 ctccaccagc cattgaaaag gcaccagcta agatagccgc aaatcctgat aaaaagataa
    19681 tccagatatt ggtcgtggca ctggcaaccc cgataaccac accagcaatg gaaataattc
    19741 catcgttagc accaagaaca cctgcgcgca ggatatttaa acgacctgca aaatttgaat
    19801 cgatttcgtg atttgtttct gacgctaaat ttcaagttca agttagccat ccagaagtct
    19861 tctctgggtg acttgtagtc caagcatttt ttaggatagt tgttaatcca cttttcgatg
    19921 aatgcgactt ctttgggagt cattttcttg gttcccttag gtaaccatct acgaatgagc
    19981 ctgttgtgat tctcattagt tcccctttcc caagaggcat aggggtgcgc ataatagatg
    20041 tgctcctcag aaaatacatc aaacaagcga ttgaattccg ttccattatc tgccgtgatg
    20101 gaaagaatct tgtgttgttt taagatgagt tttagagcct gattgaccac ctcagcactt
    20161 ttatttggaa tcaatcggat gatctgatgt ctactctttc gatccgtcaa gacaagcaag
    20221 cagtagtttt tcgctctcgt aagtagaacc gtatcaatct cataatgccc attctcc
//
LOCUS       DBJKQU010000040        18978 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.040, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000040 DBJKQU010000000
VERSION     DBJKQU010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18978
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.040"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(154..963)
                     /locus_tag="ACSUUC_001548"
     CDS             complement(154..963)
                     /locus_tag="ACSUUC_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HHQ8054735.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(965..1768)
                     /locus_tag="ACSUUC_001549"
     CDS             complement(965..1768)
                     /locus_tag="ACSUUC_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HHQ8054736.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLTFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1778..3265)
                     /gene="tacF"
                     /locus_tag="ACSUUC_001550"
     CDS             complement(1778..3265)
                     /gene="tacF"
                     /locus_tag="ACSUUC_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HHQ8054737.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3601..4308
                     /locus_tag="ACSUUC_001551"
     CDS             3601..4308
                     /locus_tag="ACSUUC_001551"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070567 - cytidylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IspD/TarI family cytidylyltransferase"
                     /protein_id="HHQ8054738.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4313..5335
                     /locus_tag="ACSUUC_001552"
     CDS             4313..5335
                     /locus_tag="ACSUUC_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HHQ8054739.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5352..6221
                     /gene="licA"
                     /locus_tag="ACSUUC_001553"
     CDS             5352..6221
                     /gene="licA"
                     /locus_tag="ACSUUC_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HHQ8054740.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            6211..7089
                     /locus_tag="ACSUUC_001554"
     CDS             6211..7089
                     /locus_tag="ACSUUC_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HHQ8054741.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7101..7790
                     /locus_tag="ACSUUC_001555"
     CDS             7101..7790
                     /locus_tag="ACSUUC_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HHQ8054742.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7876..8724
                     /gene="dprA"
                     /locus_tag="ACSUUC_001556"
     CDS             7876..8724
                     /gene="dprA"
                     /locus_tag="ACSUUC_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HHQ8054743.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9614..10657
                     /locus_tag="ACSUUC_001557"
     CDS             9614..10657
                     /locus_tag="ACSUUC_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HHQ8054744.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEHFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            10824..12911
                     /gene="topA"
                     /locus_tag="ACSUUC_001558"
     CDS             10824..12911
                     /gene="topA"
                     /locus_tag="ACSUUC_001558"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HHQ8054745.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            13132..13491
                     /locus_tag="ACSUUC_001559"
     CDS             13132..13491
                     /locus_tag="ACSUUC_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HHQ8054746.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13584..14216
                     /locus_tag="ACSUUC_001560"
     CDS             13584..14216
                     /locus_tag="ACSUUC_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HHQ8054747.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            14260..14916
                     /locus_tag="ACSUUC_001561"
     CDS             14260..14916
                     /locus_tag="ACSUUC_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HHQ8054748.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14980..16029
                     /locus_tag="ACSUUC_001562"
                     /pseudo
     CDS             14980..16029
                     /locus_tag="ACSUUC_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            16041..17078
                     /gene="leuB"
                     /locus_tag="ACSUUC_001563"
                     /pseudo
     CDS             16041..17078
                     /gene="leuB"
                     /locus_tag="ACSUUC_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            17075..17344
                     /locus_tag="ACSUUC_001564"
     CDS             17075..17344
                     /locus_tag="ACSUUC_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HHQ8054749.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            17348..17707
                     /gene="leuD"
                     /locus_tag="ACSUUC_001565"
     CDS             17348..17707
                     /gene="leuD"
                     /locus_tag="ACSUUC_001565"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HHQ8054750.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17869..18491
                     /locus_tag="ACSUUC_001566"
                     /pseudo
     CDS             17869..18491
                     /locus_tag="ACSUUC_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004915491.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            18655..>18978
                     /locus_tag="ACSUUC_001567"
     CDS             18655..>18978
                     /locus_tag="ACSUUC_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HHQ8054751.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQAN"
BASE COUNT         5980 a         3220 c         4011 g         5767 t
ORIGIN      
        1 aaaaaagtct ttaaaattat aaaacgcatc atatcaaggt ttttcaaaaa acttgatatg
       61 atgcgtttta ttgtgggaat atgtatttca ttttctacta aaattatgtt tttgaataac
      121 ctctatctta gtagtctgta taatccccct caatcagttt ttgcgataag ctttaatgct
      181 atgactatac cactcttgca tttcttttga tggtggtgtc atataatcgc catacatctg
      241 ggttaaaaat tggtcatatt ttttgggaac aggcaacata cggccctcaa actcagttaa
      301 aatcagttct ttaaaggtat caactgggaa gatttctttc atcccttcct taccgatccc
      361 aactcctcct tcatattgag gagtgttggt tacagcattt ttgactagtt gatcaatttt
      421 cttgtaaaag tagcgaggat tgacaaatcg gagagcgtac cagctacata atctaagaaa
      481 atcttttagt ttgctatcac cgtgaactgc tcgtgatttt ttgatataag ctagttgacg
      541 aagagccaca tacttatagc tcttgtcgac aatgctcaag tctgtaaatc gatcaattgg
      601 gaagacatcg atgaaaaggc tggtatcatg acgcttgtac ttaacatggt cttctataac
      661 agtagaagtg tccaaaatcg atgcgaaatt atggaagtac caagaagatg tatcgtagga
      721 aagaaccttg tagcgagggt gattttcttc ttcaataatc ttcagtaaac gctcataatc
      781 ctcacgataa agggaaatat caatatcatc atcccaagga atcatacctt tgtggcggat
      841 ggctccaagc atggttccat aactgagaaa ataaggaata tcatgtttct tacaagtctc
      901 atcaatatag tccagcaggg ctagttgaat ttctttaatt tctttttttt ctaaatattg
      961 catcctaatc ctccaattta taagcgtgaa attcatgact gtagaagcgt ttttcttctg
     1021 gtggtagggt catataatct ccataaaatt gtgtcaaaat agtatcaaat ttttcaggtg
     1081 caggaaggct taaattctca aaggttaaat cgattgtttt atcaaaggta ccacttggga
     1141 agacttcctt ttccttaaat tttgaaggaa taaaagccat atactgccca ttttcacgac
     1201 tatatttttg aatttctttc tcgattttat ttgcaaaata acgaggagaa accggtcgaa
     1261 ggagcaacca aaaggctgtt cgtatccaat cttttaaaag gctatcctta tagacaatat
     1321 ttttatgttt actgaaagac agcagtttga agctttccag tttataacaa gtatcaatga
     1381 ccttaggatc atcaaagcga tctataggga aaatatcgat aaagatacca gactcatagg
     1441 tttttgtatt tcgagtatca ataattttag tcgtactgtc ggttatcttg ataaagttgt
     1501 taaagtagtt cttatcagtt tctaaggata ggagcttata cttgcttttt tccttttgaa
     1561 aaatgttaat aaatcgttgg tagtcttctc taggcatgga cagatcaata tcgtcgtccc
     1621 aagggataaa gccctcatgt cgaaccgccc caatcagagt accgtagtta ataatatagt
     1681 tgatattgtg ctttttacag agagtatcaa tataatccaa aatttctaat tcaatttgtt
     1741 tggcatcttc aatggttagt tgtttcattt taaactccta tgattttttg aatttatttt
     1801 ttaaggctag gacatggttt aaaaattcat agaaaatgct atcttttgtg aagacaagta
     1861 gactaatata agagatagct gataacaaga caatcaaacc agtattaatc aaaaatggca
     1921 aattaatgac catatccaca ggatacacga aattaatcag gaaataaatt gctacaaagg
     1981 aaagtgaaaa gagagagtat cgaacagtat agctaaagat atgtcccaag tggatgagtt
     2041 gttttctatg gatgaaaatg atatagaaaa caagtagaga agtctctgat aacatagttg
     2101 tcagtaagta gtattcggga gccacgatat ggttgaaaaa gaggagacta ttcaagccca
     2161 aattgagtag cccagcaaag actgtataga ctgtgatacg tttttcatag ccattggtaa
     2221 agagaatttg ggaaccaaga atggtatcta aggccaggat aatcgtacga aaagcgaaga
     2281 gagaggtcaa gatgccgcct ccgatatatt tttcactacc gtaaagtagg atggcatttg
     2341 gtcctaaaac catgagtcca aaactcagtg gaatgataaa gaagttaaag attcgactac
     2401 ctctattaac cagagaaaca taggcttctt tgtctccttt ccccagatag taactgagac
     2461 gaggcacact cactccaatt gcacctgtta caaccccagc tataacggtc acaattcgct
     2521 gagctatggt atagtaacta acgttgacat caatccctgt tttaacgagg aagaggcgat
     2581 ctaaaaaagt gaagagcata ttggcattgg caaagactaa catggctgtc agagggagaa
     2641 agagtggttt aaaatcactt aggtgaatct taacaagttt gatgtctctt ttaatccaaa
     2701 aataactaat caggtagtta atcagcgtcg ataaactcat cacaagtgta tagacaacaa
     2761 tatcgtgttc atttttaaca aataagaaaa tagagaccag catcaggata cggatgaagg
     2821 cagttttgta aaagagaaaa ctgtaatttt ccagagcttc attgacccat tcgattgaaa
     2881 aaatctgggc aatgagttga atccccataa caaggtagac ctttttgacg attggattat
     2941 cagtaaagaa gagaggatag gctaggatat agacagcagt ggtcaaaatc gtacaagcga
     3001 tgcacaaata aaaaagacta gaaaaggttc tgttaagatc ttttttgtta tccttgacat
     3061 tactgatagc ccttaaaccg tagttataga caccataagt tgcaaagggc aagaaaaatg
     3121 acaaaatagt gtcgactgag ttgaagtaac catagtcagt tcggtccaag acacgcgcga
     3181 cataggttcc agttaggatg ggaaaaataa tattcaagac acgaattccc atgtaagata
     3241 gagcatttaa ttttatactt ttcattcaat ttacctcgtt tttcattata tcataaagtt
     3301 agctaataag aaatgaaggg cagtaagtca agtaatcact ttgaagtttc aaatcttaag
     3361 ttttaagttt tctttaagga aagtatatta ttctgaagga ctctaaaatt tcgcagccat
     3421 ttattagtaa ttgctacaga attcctagtc attactagaa atggactagt ttctttgaat
     3481 aatagaactg cataattctc ctattctaga aggggaggac cagtatttct tttatgatag
     3541 gactagattg tggtataata gagagaataa gtttttttag taagacaaag gagaaaatag
     3601 atgatttatg caggaattct tgccggtgga actggcacac gcatggggat cagtaacttg
     3661 ccaaaacaat ttttagagct aggtgatcga cctattttga ttcatacaat tgaaaaattt
     3721 gtcttggagc caagtattga aaaaattgta gttggtgttc atggagactg ggtttctcat
     3781 gcagaagatc ttgtagataa atatcttcct ctttataagg aacgtatcat cattacaaag
     3841 ggtggtgctg accgcaatac aagtattaag aaaatcattg aagccattga tgcttatcgt
     3901 ccgcttactc cagaggatat cgttgttacc cacgattctg ttcgtccatt tattacactt
     3961 cgcatgattc aggacaatat ccaacttgcc caaaatcatg acgcagtgga cacagtggta
     4021 gaagcggttg atactatcgt tgaaagtacc aatggtcaat ttattacaga tattccaaat
     4081 cgtgctcacc tttatcaagg acaaacacct caaacattcc gttgcaagga cttcatggac
     4141 ctttatggat ctctttctga tgaagagaag gaaatcttga cagatgcatg taaaatcttt
     4201 gtgatcaaag gaaaagatgt ggccttggcc aaaggtgaat actcaaatct gaagattaca
     4261 accgtaacag atttgaagat tgcaaaaagt atgattgaga aagactagta aaatgattaa
     4321 tcaaatttat caactaacta agcctaagtt tatcaatgtc aaatatcagg aagaggctat
     4381 tgaccaagag aatcatatcc ttatccgtcc caactacatg gctgtctgtc atgcggatca
     4441 gcgttactat cagggaaaac gtgatcccaa gattttgaat aaaaagcttc caatggcaat
     4501 gattcacgag tcatgtggaa ccgtcatttc tgacccgacc ggaacctacg aggttggtca
     4561 aaaagttgtc atgattccca atcagtctcc tatgcagagt gatgaagaat tctatgaaaa
     4621 ctacatgaca gggacccatt tcttgtctag tggatttgat ggctttatga gagagtttgt
     4681 ttctctccct aaagatcgtg tggtggctta tgatgctatt gaagatacgg ttgcagccat
     4741 tacagagttt gtcagtgtgg gcatgcacgc tatgaatcgt ctattgactc ttgctcatag
     4801 caagcgggag cggatcgccg ttattggaga tggaagttta gcttttgtgg ttgccaatat
     4861 tatcaactat actttgccag aagcagagat tgtggttatt ggtcgtcatt gggaaaagtt
     4921 ggaactcttc tcatttgcca aagaatgcta tattacggat aatattcctg aagatttggc
     4981 ctttgaccat gcttttgaat gttgtggtgg tgatggtact ggaccagcta ttaatgactt
     5041 gattcgctac attcgtcctc agggaacgat tctcatgatg ggagttagcg aatataaagt
     5101 caatctcaat actcgcgatg ccttagaaaa gggcttgatt ttggttgggt catctcgttc
     5161 tggtcgcatt gattttgaaa atgctatcca aatgatggaa gtcaagaaat ttgccaatcg
     5221 tcttaaaaat atcctttatc tagaagaacc tgtaagagaa attaaagata ttcatcgtgt
     5281 ctttgcaacc gatttaaaca cagcctttaa aacagtgttt aagtgggaag tataagtact
     5341 ggaggttaat tgtggagaaa atcattaaag aaaaaatttc ttccttactt agtcaagaag
     5401 aggaagtcct cagtgttgaa caactgggtg gaatgaccaa tcaaaactat ttggccaaaa
     5461 caacaaataa gcaatacatt gttaaattct ttggtaaagg gacagaaaag cttatcaatc
     5521 gacaagatga aaagtacaat cttgaactac taaaggattt aggcttagat gtaaaaaatt
     5581 atctttttga tattgaagct ggtatcaaag taaatgagta tatcgaatct gcgattacgc
     5641 ttgattcaac gtcaatcaag accaagttcg acaaaattac tccaatatta caaactattc
     5701 atacgtctgc taaggaatta agaggagaat ttgctccttt tgaagaaatc aaaaaatacg
     5761 aatccttgat tgaagaacaa attccttatg ccaactatga atctgttaga aatgcagtct
     5821 tctccttaga gaaaagactg gctgacttag gtgttgacag aaaatcttgt catatcgatt
     5881 tggtgcctga aaactttatc gaatcacctc aaggacgact ttatttgatt gactgggaat
     5941 attcatcaat gaatgatcca atgtgggatt tggctgccct ctttttagag tctgaattca
     6001 cttcccaaga ggaagaaact ttcttatctc actatgagag tgaccaaaca ccggtttctc
     6061 atgaaaagat tgctatttat aaaattttac aagatactat ttggagtcta tggactgtct
     6121 ataaggaaga gcaaggtgaa gattttggtg actatggtgt gaatcgttac caaagagcta
     6181 ttaaaggttt ggcttcttat ggaggttcag atgaaaagta aaaacggagt tccttttggc
     6241 cttctctcag gtattttctg gggcttgggt ctaacggtta gtgcttatat cttttcgatt
     6301 tttacagatt tgtcaccctt tgtggtggct gcaactcatg attttttgag catctttatc
     6361 ttactagctt ttctcttggt aaaagaaggg aaagttcgcc tctcaatttt cttaaatatt
     6421 cgcaatgtca gtgttatcat aggagccttg ctagcaggcc ctatcggtat gcaggccaat
     6481 ctttatgcag ttaagtatat cggaagttct ttagcttcat ctgtatcggc tatttaccct
     6541 gcgatttcag ttctattggc tttcttcttt ttgaagcaca agatttcgaa aaatactgta
     6601 tttgggattg tcttgattat tggagggatt attgcccaga cctataaggt tgaacaggtt
     6661 aattctttct acattgggat tctttgtgct ttggtttgtg ctattgcatg gggaagtgag
     6721 agtgttctta gctcttttgc catggaaagt gaattgagtg aaatcgaagc cctcttaatc
     6781 cgtcaagtaa cttcgttctt gtcctatctt gtgattgtgc tcttctctca tcagtcattt
     6841 gttgcagtag ccaatggaca attgctaggt ctcatgattg tctttgtagc ctttgatatg
     6901 atttcctatt tggcttatta tatcgctatc aatcgcttgc aaccagccaa ggctacaggc
     6961 ttgaacgtga gctatgtagt atggactgtc ttgttcgcag ctcttttctt gggaacatca
     7021 ttagatatgc tgaccattat gacgtcactt gtcgtcattg ctggagttta tattattatt
     7081 aaagaataaa ggagattcgt gtgaaagcca ttatcttagc agcgggattg ggaactcgct
     7141 tgcgtcctat gactgaaaat acccctaaag ccttggttca ggttaatcaa aaacctttga
     7201 ttgaatacca aattgagttt ctcaaagaaa aaggaatcaa tgacatcatc atcatcgttg
     7261 gttatcttaa agaacaattc gattatttaa aagaaaaata cggtgttcgc ctcgttttca
     7321 atgataaata cgctgactac aataactttt actctctcta tcttgtaaaa gaagaattgg
     7381 ccaacagcta tgttattgat gctgacaatt atctctttaa aaatatgttc cgcaatgatt
     7441 tgacacgttc gacttatttt agtgtttatc gtgaagattg taccaacgaa tggttcttgg
     7501 tctatggaga tgactacaag gttcaagaca ttattgttga tagcaaggca ggtcgcatcc
     7561 ttagtggtgt atccttctgg gatgctccaa ctgcagaaaa gattgtcagc tttatcgaca
     7621 aggcttatgc aagtggtgaa tttgttgatc tctactggga caatatggtt aaggataata
     7681 tcaaagagct agatgtctat gttgaagaat tagaaggcaa tagcatttat gagatcgata
     7741 gtgtccaaga ctatcgtaaa ttagaagaaa ttcttaaaaa cgaaaattaa agattccaac
     7801 atctgacaaa atagtcggat gttttttgat tttttacgaa tagatagatg agtagaaaaa
     7861 gaaatggagt tatttatgaa aatcacaaac tatgaaatct ataagttaaa aaaatcaggt
     7921 ttgaccaatc aacagatttt gaaagtgcta gaatacggtg aaaatgttga tcaggagctt
     7981 ttgttgggtg atattgcaga tatctcaggt tgccgtaatc cagccgtttt tatggaacgt
     8041 tattttcaga tagacgatgc gcatttgtcg aaagagtttc aaaaatttcc atctttctct
     8101 attttagatg actgttatcc ttgggatttg agtgaaatat atgatgcgcc tgtactttta
     8161 ttttacaagg gaaatcttga cctcctgaaa ttcccgaagg tagcggtcgt gggcagtcgt
     8221 gcttgtagca aacagggagc taaatcagtt gaaaaagtca ttcaaggctt ggaaaatgaa
     8281 ctggttattg tcagtggtct ggccaagggc attgacacag cagctcatat ggcagctctt
     8341 cagaatggcg gaaaaaccat tgcagtgatt ggaacaggac tggatgtgtt ttatcctaaa
     8401 gccaataaac gcttgcaaga ctacatcggc aatgaccatc tggttctaag tgaatatgga
     8461 cctggcgaac aacctctgaa atttcatttt cctgcccgta atcgcatcat tgctggactt
     8521 tgtcgtggtg tgattgtagc agaggctaag atgcgttcag gtagtctcat tacgtgtgag
     8581 cgagcaatgg aagaaggacg cgatgtcttt gctattcctg gtagcatttt agatggacta
     8641 tcagacggtt gccatcattt gattcaagaa ggagcaaaat tggtcaccag tgggcaagat
     8701 gttcttgcgg aatttgaatt ttaaaaatga cctaagctag aattctaaga aaaaatcaat
     8761 tttaagagaa aatgaaccca acatttccat aataaaacgc atattagcaa gtttttaaca
     8821 cttgataata tgcgtttttt ctaagtggat tagtagagta gaggattttt ctcatataat
     8881 actcttcgaa aatctcttca aactacgtca gcttccatct gcaacctcaa aacagtattt
     8941 tgagctgact tcgtcagtct tatctacaac ctcaaagcag tgctttgagc aacctgtggc
     9001 tagcttccta gtttgcgctt tgattttcat tgagtataag ggaaagtata gtgaattgaa
     9061 ataagatgtg aacaactcta tcaggaaagt caaattgatt tatagaaata ttttagcagc
     9121 caaggtgcac tgttatagat tcaatacact ataatttagt gtaattgaga aaggagaaat
     9181 gattgtgatt gatgttggct aggttatgtt caatgattcc taccgtctca aatcttgtca
     9241 gtaaggaaaa ataaattctt caaaagtaga gattacaagg cttgtttaag aaagaattca
     9301 aagaccttga caaataaaaa taaaatggtt attataaaaa aatggtctga aatagatgat
     9361 gatacttttc gaaaatctct tcaaactacg tcagctcagc tttgccttgc tgtgttttga
     9421 gcaagctacg gttagcttcc gagtttgatt ttcatttact agaaatgaaa ctgatgagag
     9481 atatcagtag acatttgagt caggatatta tggaaaatga taaaaagagc tcgtgagatt
     9541 ggcatatcag actactaaag tattgagttt gttaggattt tagcgactag ttagctggga
     9601 aaggaagata tttgtgacaa ataataaact gtattcgttg atagaattta gaaataaaat
     9661 atatgaagaa ttagaacttt ccagaagtga tttagcgatt ttactatgtg ccatgcttat
     9721 cgcctctatc ggattaaata tggattcgac tcccgtgatt attggagcca tgttaatctc
     9781 tcctttgatg acacctattc tgggagtggg gctctctcta gctatatttg attttaaatt
     9841 gttaagaaaa tcttttaaaa tattagctat tcaaattctt gccagtttaa tagcttcaac
     9901 actttatttt tatctttctc ccatttcgta tgctagttcg gaaattgttg ctagaacctc
     9961 tccgactatt tgggatgttc tcattgcttt tgtaggaggg atagcaggta ttattggtgc
    10021 taggaaaaaa gagaccaata atattgttcc tggtgttgct attgcaaccg ccttgatgcc
    10081 tcctctttgt acagtaggtt atgctattgc ttctgctaat ctaaaattta tcataggctc
    10141 ctcttaccta ttcctcatca attgtagctt tattgtcatt gcgacttata taggtgttag
    10201 gttgatgatg gttaagaaac attattttaa agataatgaa gaagactcta aaatgcgtag
    10261 gattttgctt ctagttgctg ttttgctgat gattccgagt ttcatctctg caacgacttt
    10321 agtgagagaa acgttgaaaa aagagtccct taagaaattt atatcagagc agtttcaggg
    10381 gtataatatt ttgaaaaaaa cctattctaa aaagactcat accctaaagc taaccatttc
    10441 aggaaattat ttgacagaag aagaactcga tatgatttca agtaagagag gtgactatgg
    10501 tttaagtgat gtttctgttc aagtttcaca attgtctgat tcagaacaac ttagtaagga
    10561 agagctggtg gagcatttct tccagtatat caaggataag gaagcaaaag aaaaggagaa
    10621 agccaataaa tttgatacag agtctgagga gcaataattt cttgagaata gctggtttct
    10681 ctcgtgagtc ttctatgtat atcaaaggaa gactgaggtt ttaagtataa aacttttctt
    10741 ctattatagt agctaagtct tgacagggtt caaaaaatgg tttacacttt ataaagttta
    10801 ttactttgaa aaggtgtgat actgtggcta cggcaacaaa aaagaaaaaa tcaacagtta
    10861 aaaaaaatct agtcatcgtg gagtcgcctg ctaaggccaa gacgattgaa aaatatctag
    10921 gcagaaacta caaggtttta gccagtgtcg ggcatatccg tgatttgaag aaatccagta
    10981 tgtccgtcga tattgaaaat aattatgaac cgcaatatat caatatccga ggaaaaggcc
    11041 ctcttatcaa tgacttgaaa aaagaagcta aaaaagctaa taaagttttt ctcgcgagtg
    11101 acccggaccg tgaaggagaa gcgatttctt ggcatttggc ccatattctc aacttggatg
    11161 aaaatgatgc caaccgtgtg gtcttcaatg aaatcaccaa ggatgcagtc aaaaatgctt
    11221 ttaaagaacc tcgtaagatc gatatggact tggtcgatgc ccaacaagct cgtcggatct
    11281 tggatcgctt ggtagggtat tcgatttcgc ctattttgtg gaagaaggtc aagaagggct
    11341 tgtcagcagg tcgcgttcag tccattgccc ttaaactcat cattgaccgt gaaaatgaaa
    11401 tcaatgcctt ccagccagaa gaatactgga cagttgatgc tgtctttaaa aagggaacca
    11461 aacaatttca tgcttccttc tatggagtag atggtaaaaa gatgaaactg accagcaata
    11521 acgaagtcaa ggaagtcttg tctcgtctga ctagtaaaga cttttcagta gatcaggtgg
    11581 ataagaaaga gcgcaagcgc aatgctcctt taccctatac cacttcatct atgcagatgg
    11641 atgctgccaa taaaatcaat ttccgtactc gaaaaaccat gatggttgcc caacagctct
    11701 atgaaggaat taatatcggt tctggtgttc aaggtttgat tacctatatg cgtaccgatt
    11761 cgactcgtat cagtcctgta gcgcaaaatg aggcggcaag cttcattacg gatcgttttg
    11821 gtagtaagta ttctaagcac ggtagcaagg tcaaaaacgc atcaggtgct caggatgccc
    11881 atgaggctat tcgtccgtca agtgtcttta atacaccaga aagcatcgct aagtatctgg
    11941 acaaggatca gctcaagcta tataccctta tctggaatcg ttttgtggct agccagatga
    12001 cagcggccgt ttttgatacc atggctgtta aattgtctca aaaaggggtt caatttgctg
    12061 ccaatggtag tcaggttaag tttgatggtt atcttgccat ttataatgat tctgacaaga
    12121 ataagatgtt accggacatg gttgttggag atgtggtcaa acaggtcaat agcaaaccag
    12181 agcaacattt cacccaaccg cctgcccgtt attctgaagc aacactgatt aaaaccttag
    12241 aggaaaatgg ggttggacgt ccatcaacct acgcgccaac cattgaaacc attcagaaac
    12301 gttattatgt tcgcctggca gccaaacgtt ttgaaccgac agagttggga gaaattgtca
    12361 ataagctcat cgttgaatat ttcccagata tcgtaaacgt gaccttcaca gctgaaatgg
    12421 aaggtaaact ggatgatgtc gaagttggaa aagagcagtg gcgacgggtc attgatgcct
    12481 tttacaaacc attctctaaa gaagttgcca aggctgaaga agaaatggaa aaaatccaga
    12541 ttaaggatga accagctgga tttgactgtg aagtgtgtgg cagtccaatg gtcattaaac
    12601 ttggtcgttt tggtaaattc tacgcttgta gcaatttccc agattgccgt catacccaag
    12661 caatcgtgaa agagattggt gttgagtgtc caagctgtca tcagggacaa attattgagc
    12721 gaaaaaccaa gcgtaatcgc ctattctatg gttgcaatcg ctatccagaa tgtgaattta
    12781 cctcttggga caagcctgtt ggtcgtgact gtccaaaatg tggcaacttc ctcatggaga
    12841 aaaaagtccg tggtggtggc aagcaggttg tttgtagcaa aggcgactac gaggaagaaa
    12901 agattaaata agaggagggg cccgaaagta aatttcaggc tccttttggt tagaacttga
    12961 caaaatacat cattttatgc gaaactagaa gaagattatt ttatactcaa tgagaatcaa
    13021 agagcaaatt agaaagctag tcgcaggttg ctcaaagcac tactttgagg ttgaagatgg
    13081 aagctgacct ggtttgaaga gattttcgaa gagtattaac taggagaagt tatgcgtatt
    13141 atctatctaa ttattggttt tttatcgctg accttggcta ttgttggggt tgttttaccc
    13201 ttgttgccta caacaccttt ccttttgttg tctattgctt gtttctccag aagttccaag
    13261 cgattcgaag attggcttta tcataccaag ctctatcaag catatgtagc tgattttcgt
    13321 gagaccaagt ctattgcgcg tgaacgaaag aaaaaaatca tcgtctctat ctacgtcttg
    13381 atgggaattt ctatttattt tgcacctctt ttaccagtca aaatcggtct gggtgctttg
    13441 accatcttta ttacttatta tctcttcaag gtcattccag acaaagaata gttaaaacag
    13501 tagttatttg ccttgataaa attgaaagca tattcataac aatatgatat aataaaattg
    13561 aagtaatatt caaggagaat caaatgattt acgaattttg tgctgaaaat gtgactttac
    13621 ttgaaaaagc gatgcaggct ggagctcgtc ggattgaact ctgtgataat ctagcagttg
    13681 gtgggacaac acccagctat ggagtgacta aggcagcggt tgaactggca gctaactacg
    13741 atacaaccat catgaccatg attcggccac gtggtggtga ctttgtctat aatgacctag
    13801 aaattgctat catgctagaa gacattcgtt tgactgctca ggctggaagt caaggggttg
    13861 tatttggagc tttaactgct gataaaaagt tggataagcc taatctggaa aagttaattg
    13921 ctgcatcaaa aggaatggaa attgtctttc acatggcctt tgatgaacta agtgatgaag
    13981 atcaaccgga agctattgac tggctcagtc aagccggtgt cactcgtatc ctaactcgtg
    14041 ctggtgtgtc tggcgactcc ttagaaaaac gttttgttca ctatcacaga attttggagt
    14101 acgctaaagg taaaattgaa attctaccag gtggggggat tgaccttgaa aaccgtcaaa
    14161 cctttatcga ccaggtgggg gtaacacaat tgcatggtac taaggttgtt ttttaaaaaa
    14221 tagaaaggaa ctgctagctt tgggtagcag ttttcactta tgtttgaaat ttttaaatcc
    14281 tatcaattta atcaagaaaa ggctcatgat tatggtttta tagaaaatag cgaagtctgg
    14341 acatatagtt gccagatttt gcaaggtgac tttgtcatga ctgtgtccat cactgctgat
    14401 aatgtgaact ttcaagtctt tgaccaagag actggtgacc tctatcctca cgtttatatg
    14461 gaaagcatga ggggaagttt tgtcggaaat gtccgtgagg cttgtctgga gattctttac
    14521 cagattcgga aggcttgttt tgatgtgcaa gattttatct gtcatcagac taagcgtatc
    14581 atgactcaag ttcaggaaaa gtatggaaac cagttggagt atctgtggga aaaatcgcct
    14641 gatacagctg tattgcgcca tgaaggcaat caaaagtggt atgccgtctt gatgaaaatc
    14701 tcttggaata agctggaaaa gggcagagaa ggacaagtgg aagcagtcaa cctcaagcat
    14761 gaccaagtag ctaatttgct ttcacaaaag gggatttatc cagccttcca tatgagcaag
    14821 cgctactgga ttagtgtgtc ccttgatgat actttatcag atgaagaagt actggaattg
    14881 atagaaaaaa gttggaactt aacctctaaa aaatgaaata ttttaataat tttcatgaac
    14941 tttcaattag ctaaatattc tttactgaag agatttttag aaaatatagg atttaccaca
    15001 ctagaggaat atggtgccat cttcaaatac ctgattgaga atgtcaagac ggatcgtcag
    15061 atcatctatt cgcctcactg tcatgatgac ctcggaatgg cagtggcaaa tagccttgct
    15121 gctgtcaaga atggtgcagg acgtgttgaa gggactatca atggtattag ggagcgagct
    15181 gaaaatgctg ctttggaaga aattgcagtg gctctcaata ttcgccaaga ttactaccaa
    15241 gtagaaacca gtattgtcct aaatgagacc atcaatacgt cagaaatggt ttctcgcttc
    15301 tctggtattc cagttcctaa aaacaaagcc gtcgttggtg gcaatacctt ctcccacgaa
    15361 tctggtattc accaagatgg agtccttaaa aatcctctca cttatgagat catcacacct
    15421 gaattggttg gtgttaagat tctgcttgga aaattatctg gtcgccatgc ttttgttgag
    15481 aaactgagag aattggccct agattttaca gaagaggata tcaaaccact ctttgctaag
    15541 ttcaaggcac tggtcgataa gaagcaagaa atcacagatg cagatattcg agctttggta
    15601 gctggaacca tggttgaaaa tccagaaggc ttccactttg atgatttaca acttcaaact
    15661 catgcagata atgacattga agcgctcgtt agcctagcca atatggatgg tgagaaagtc
    15721 gaatttaatg cgacagggca aggttccgtt gaagcaatct ttaatgctat cgataagttc
    15781 tttaaccaat ctgttcgttt ggtgtcctac actatcgatg cggtaacaga tggaatcgat
    15841 acccaggatc gggttttggt cactgttgaa aacagagata cagaaaccat ctttaatgca
    15901 gcagggcttg attttgatgt gttgaaggct tctgctattg tctatataaa cgctaatacc
    15961 tttgttcaaa aagagaatgc aggtgagatg ggacgcagtg tttcttacca cgatatgcct
    16021 agtgtgtaaa ggagaaggct atggcaaaga aaatagtagc tctagcagga gacggaattg
    16081 gcccagaaat catggaggtt ggtttagaag ttctggaggc tctagctgaa aaaacaggtt
    16141 ttgactatga gattgacaga cgaccgttcg gaggtgcaga tattgatgca gcatgacctc
    16201 ccttacctga tgaaaccctt aaggcaagta gggaagcaga tgctatccta ctagtagcta
    16261 tcggtagtcc tcagtatgat ggagcagtgg ttcgccctga acaaggcctg atggctctcc
    16321 gtaaggaact caatctttac gctaatattc gtcctgtaaa aatctttgac agtctcaagc
    16381 atttgtcact actcaaactg gaacgaattg ctggtgtaga ctttgtcgtg gtgcgtgaat
    16441 tgacaggcgg gatttacttt ggagatcata ttcttgaaga gcgcaatgcg cgtgatatca
    16501 acgactatag ctatgaggaa gtggagcgga ttattcgcaa agcctttgaa attgcaagaa
    16561 atcgcagaaa aatcgttact agtatcgata agcaaaatgt tctagcgacc tcaaaactct
    16621 ggcggaaagt agctgaggaa gtcgcacagg atttcccaga tgtaaccttg gaacatcagc
    16681 tggtagactc agctgctatg cttatgatta ccaatcctgc taagtttgat gttattgtaa
    16741 cggagaatct ttttggagat attttatctg atgaatcaag cgtcttatct ggtacacttg
    16801 gggttatgcc atcagccagt cattctgaaa atggaccaag tctctatgaa cctattcaca
    16861 gttcagcacc tgatattgca ggtcaaggaa ttgccaatcc tatttccatg attttatcag
    16921 tttccatgat gttgagagat agtttcggac gttatgagga tgcagagcgt atcaaacgtg
    16981 ctgttgagac aagtctggcg gcaggaattt taacgagaga tataggaggt caggcttcaa
    17041 caaaggaaat gacggaagct attattgcaa ggttatgaag ttagacgaaa aaattactct
    17101 agtccttttg atttggaatg tcatcatttt cttgatttat ggtattgaca aatctaaggc
    17161 aaggagaaga gtttggcgca tccctgagaa aatcttactt attttagcct ttacttttgg
    17221 tggttttggt gcctggctag caggaatcat ctttcaccac aagactcgaa aatggtactt
    17281 taaaatagtt tggtttcttg ggatggtgac cacactagta gccttatatt ttatttggag
    17341 gtaatggatg gcagggtctt cgagggaata cgctgcttgg gctctagcgg actatggttt
    17401 taaggtcgtg attgcaggat ctttcggtga cattcattac aataatgaac tcaataatgg
    17461 catgttgcca atcgttcagc ctagagaggt tagagagaaa ctagcccagc taaaaccaac
    17521 cgaccaggta actgtggact tggaacaaca aaaaatcatc tcaccagttg aagaattcac
    17581 cttcgagata gatagcgagt ggaaacataa actcctaaat agtttggatg atatcggtat
    17641 taccttgcag tatgaagagt tgattgctgc ttatgaaaaa caacgaccag cctactggca
    17701 ggattagaaa aaatagaaaa ggagatatag taaactgaaa taagatgtaa acaaatgaat
    17761 tggagcttaa catccatttc cagcaatttt ttagaaacta cagtggacta ttctggattc
    17821 aacacattat aaaattatga caaaacacat tcacaagaag gctacgacat tttaaaaggt
    17881 gagggcggat gtatcgtttg ccctactaaa gttggttaca ttatcatgac cagtgacaag
    17941 gcaggacttg agcgtaagtt cgcagccaaa gaacgtaagc gtaacaaacc aggtgttgtt
    18001 ctctgcggta gcatggatga actttgcgct ttagcgcaac tcaacccaga aattgaagca
    18061 ttctactaaa aacattggga tgaagatatt cttcttggtt gtatccttcc ttggaaacca
    18121 gaagcctttg aaaaactcaa agcatacggg gatggccgtg aagaacttat tactgatgta
    18181 cgtggtacta gctgttttgt tatcaagttt ggaaaagcag gtgaacaatt ggctgccaag
    18241 ctttgggaag aaggtaaaat ggtctacgcc tcatctgctt caatgacaaa acgattgaaa
    18301 ctcgctatga gcaaggtgta atggtgtcta tggtcgataa ggacggcaaa ctcatcccag
    18361 aacaaggagg agcacgttca acttcaccag ctccagttgt gatccgtaaa gggcttgaca
    18421 ttgataaaat catgatgcac ctgtcagata cttttaactc atgggactac cgtcaggttg
    18481 agtattatta ggatagagaa gaagtctagt gttatgagat attaaagctc ctaacactgg
    18541 gcttttgttt agaatttctt ttctttttct ataggatatg gtattctatg tagaaaatat
    18601 atgttaataa gtaatgccaa tatttaaaca tcattagtaa aaggagttag attgatgaat
    18661 aaaagaaaag ttagtttaga agatttttat aaatggtata gtctaaataa agaagagtta
    18721 ttaaataagg caactgttgg tgaaaagttt aatgataaat taaaagaaga gtttctccag
    18781 gaatggcctt tggataggat tttaacaatg tcaatcgatg aatatgtaat aggaaaggga
    18841 cagcaaaata agtctttatg ctacgctctt gagaagggaa aatacaaaaa tctatttctt
    18901 ggaatttctg gtggctcagc ttcaaaattt ggtatttatt ggaataaaaa aacaaacaaa
    18961 tataaagatc aagctaat
//
LOCUS       DBJKQU010000041        18907 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.041, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000041 DBJKQU010000000
VERSION     DBJKQU010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18907
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.041"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            189..527
                     /locus_tag="ACSUUC_001568"
     CDS             189..527
                     /locus_tag="ACSUUC_001568"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HHQ8054752.1"
                     /translation="MTLTIHVYYKGDGDCAIKFAREMLESGLVAEIRCQKGNLKYEYF
                     LPIEKEGIILLIDQWINQEALDEHHQSNTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            717..2153
                     /locus_tag="ACSUUC_001569"
     CDS             717..2153
                     /locus_tag="ACSUUC_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HHQ8054753.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKKVILSNGESVE"
     gene            2205..2444
                     /locus_tag="ACSUUC_001570"
     CDS             2205..2444
                     /locus_tag="ACSUUC_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET transporter"
                     /protein_id="HHQ8054754.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2574..2888
                     /locus_tag="ACSUUC_001571"
     CDS             2574..2888
                     /locus_tag="ACSUUC_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HHQ8054755.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIATAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            3006..4985
                     /locus_tag="ACSUUC_001572"
     CDS             3006..4985
                     /locus_tag="ACSUUC_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHQ8054756.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFISIFEKIK"
     gene            4995..5309
                     /locus_tag="ACSUUC_001573"
     CDS             4995..5309
                     /locus_tag="ACSUUC_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HHQ8054757.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5340..5846
                     /locus_tag="ACSUUC_001574"
     CDS             5340..5846
                     /locus_tag="ACSUUC_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054758.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5926..7272
                     /gene="celB"
                     /locus_tag="ACSUUC_001575"
     CDS             5926..7272
                     /gene="celB"
                     /locus_tag="ACSUUC_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HHQ8054759.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7652..7828
                     /locus_tag="ACSUUC_001576"
     CDS             7652..7828
                     /locus_tag="ACSUUC_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054760.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8238..10451
                     /locus_tag="ACSUUC_001577"
     CDS             8238..10451
                     /locus_tag="ACSUUC_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HHQ8054761.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10673..11149)
                     /locus_tag="ACSUUC_001578"
     CDS             complement(10673..11149)
                     /locus_tag="ACSUUC_001578"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HHQ8054762.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11372..14572
                     /locus_tag="ACSUUC_001579"
     CDS             11372..14572
                     /locus_tag="ACSUUC_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HHQ8054763.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            14952..15337
                     /gene="tnpA"
                     /locus_tag="ACSUUC_001580"
                     /pseudo
     CDS             14952..15337
                     /gene="tnpA"
                     /locus_tag="ACSUUC_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15716..16345)
                     /locus_tag="ACSUUC_001581"
     CDS             complement(15716..16345)
                     /locus_tag="ACSUUC_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HHQ8054764.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(16355..17356)
                     /locus_tag="ACSUUC_001582"
     CDS             complement(16355..17356)
                     /locus_tag="ACSUUC_001582"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HHQ8054765.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17387..18028)
                     /locus_tag="ACSUUC_001583"
     CDS             complement(17387..18028)
                     /locus_tag="ACSUUC_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HHQ8054766.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18047..18862)
                     /locus_tag="ACSUUC_001584"
     CDS             complement(18047..18862)
                     /locus_tag="ACSUUC_001584"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HHQ8054767.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         6110 a         2965 c         3931 g         5901 t
ORIGIN      
        1 gaggctcttt tgtcttgttc ttgtttcaat tgactataaa tcgctataag aaaaaatcat
       61 tttattggta taaagaagtg attgaaagta atggcgaaac gttagataat tagttcataa
      121 aaaacaagtt tagatcctca tctaaacttg tttttttaaa attgaaggat gattttggag
      181 gatatgagat gacattgact attcatgtat attataaagg cgatggagat tgtgcaataa
      241 agtttgcaag agaaatgctt gaatctgggc ttgtcgcaga aattagatgt caaaaaggta
      301 atttgaaata cgaatatttt ttaccaattg aaaaagaggg aattattctc cttattgatc
      361 agtggataaa tcaagaagct ttagatgaac atcatcaatc aaatacaatg cagaaaatct
      421 tagatttaag aaaaaaatat cacttgcaga tgcaagttga acgttatata gaagatgatt
      481 ctgggatgcc agaaagcgat aagtcgttta tagacacagg gaattagaat tattgtgaga
      541 gtttttgtag tttgaaagta ttgaaaatcg taaagatatc attacgagaa tacaagaaga
      601 tattgttcta tttccattaa aaattacttc tttccttaat aataaggaaa aagaatacgt
      661 tttcatcttt tggtttgagg tttataataa gaatatcaaa gtcaggagga aaaaagatga
      721 ctacttttaa agatggattt ttatggggtg gtgctgttgc tgctcatcaa cttgaaggcg
      781 gatggcaaga aggtggcaaa ggaattagtg ttgctgatgt tatgactgct ggtcgccatg
      841 gagtagctcg tgaaattact ttgggagttt tagagggtaa atattatcca aatcatgagg
      901 cgatagattt ttatcatcgt tataaagaag acatagcact ttttgctgaa atgggattca
      961 agtgcttccg tacctctatt gcatggacac gtatctttcc aaaaggtgat gagttagagc
     1021 cgaatgaaga aggattacag ttttatgata atctttttga tgaatgctta aagaatggta
     1081 ttgaacctgt catcactcta tctcattttg aaatgcctta tcacttagtg accgaatatg
     1141 gtggttggaa aaataggaaa ttgattgatt tctttgctcg ttttgcagaa gtcgtattta
     1201 aacgttacaa agataaggtt aaatattgga tgactttcaa tgaaatcaat aatcaagcga
     1261 attatcagga agattttgca ccatttacta actcaggtat tgtatatgag gaaggtgata
     1321 atagagaagc aattatgtat caagcagcac attacgaatt agttgcttct gcacgagctg
     1381 taaaaattgg tcatgagatt aatccagatt ttcaaatagg ttgtatgatt gcgatgtgtc
     1441 caatttatcc agttacttgc aatcctaagg atatcttaat ggcaatgaaa gctatgcaga
     1501 agcgttatta ttttgctgat gtgcatgttt taggtaaata tcctgagcat attttcaagt
     1561 attgggaacg aaaaggtatt tcagttgatt ttactgacca ggataaagaa gatttacttg
     1621 gtgggactgt agattacatt ggtttcagtt actatatgtc ctttgctata gactctcatc
     1681 gtgaaaataa tccttatttt gattatcttg aaacagaaga tttagtgaaa aataattatg
     1741 ttaaggcttc tgaatgggag tggcaaattg atccagaagg tttacgttat gcgttaaatt
     1801 ggtttacaga ccactatcac ttaccactct ttattgttga aaatggtttt ggagctatag
     1861 atcaagttgc agcagatggt atggtacatg atgattatag aattgaatat ctaggtgccc
     1921 atattcgtga aatgaaaaag gctgtagttg aagatggtgt tgatttaatg ggttatactc
     1981 catggggatg tattgatttg gtttcagctg gtaccggtga aatgcggaaa cgttatggct
     2041 ttatttatgt agataaagat gacaatggga agggaagtta taatcgttcc ccgaaaaaat
     2101 cttttggctg gtataagaaa gttattttat ctaacggtga atcagtagaa tagtataaac
     2161 aaactgagat tattctcagt ttgtttagca tattgaggag acatatgatt ggaagtattg
     2221 cagcaatttt aacaacattt gcatttttac cacaagtttt tcgtgtagtt aagacaaagg
     2281 acacaggatc tattgctcta ggtatgtatg ttatgcaagt tattggtatt gcattgtggc
     2341 ttgctcatgg tattcgtata ggagacttgc ctttgatttt agcaaatagt gtttcatttc
     2401 tactctcagg aataatttta ttttataaat tgaagtataa ataatttttt tccatatcat
     2461 ttaggaaaat gagggaattg tcattgaaaa cgctttattt tataataaaa atagataaca
     2521 aataagccaa cttagcacag ctttgattgg atttaagaaa aggagaaaat attatggcaa
     2581 aagctttaat tatttgtgca gcaggaatgt cttcatcact tatggcacag aaaacaacag
     2641 agtttctaaa aggaaaaggg aaagatattg tagttgatgc tattagtgct actgaaggag
     2701 ggaaagctat cgcaacagca gcttttgatt tgtatcttgt cagtcctcaa acaaaaatgt
     2761 actttaagca atttgaagag gctggttcta aagcaggaaa accagttgta caaatacctc
     2821 ctcaagccta tattcctatt ccaatgggaa ttgaaaaaat ggctaatttg attcttgaga
     2881 atatttgatg aacacatgaa atgtcaataa atatttaagt taagataaat tgttttgagt
     2941 ttgatataaa ttgatttaag tgtataatat gcttcaatat atgaaaacat acgttttagg
     3001 agggaatgaa tgtgttaaac attaaagaga aagatatcct tcaattttta ataaaaaata
     3061 aggaacgttt tgttacaagc aaagaactgg cagaatattt atcctgttca gatagaactg
     3121 tccgtaatgt actgaaatta attgagaaga caatgattat tcaaggagtc cggttgattt
     3181 caaaacaagg tcaagggtat caaatatttt ttgagaatca aggcgcttac caggagttta
     3241 gacaaactta tgaactggaa gaagactata cgaaaactgc ggtttcaaaa ggtgatgatc
     3301 gtttagtatt tatcttaaat aaattattat ttgagcaagt tccagttctt tttgatgatt
     3361 tagctgatga actttacgtt agtcgttcaa cattatctca tgatttcaga aagatacgag
     3421 tgatgttatc agagtataat ttgtccattg agagtagggc gaataaagga gtttatgtct
     3481 caggcgagga acgtgataaa cgacgtttta tcataaatta tttcctagag aatcaatttt
     3541 ttaaaacaat acattgctat gtaaaattta acttttttgc tcaaactgtt ccattagaag
     3601 aatttgctag aattgttttg gatgaatgcc aagaggccaa cctaaaacta tctgattttg
     3661 tactacagaa tttagtagtt cacatagcat tgtctgtgat tcgtttaaaa tccggatttg
     3721 aaataaaaaa tatagactgt cagatgactg atgatgcaat agagagaaag gttgctcaaa
     3781 gaattctttc taaagtaaga gaagtaacaa atcaggaatt tccagttcag gaaatagact
     3841 acattacttt gcatttgtta gctaagagtc aacaatgtca aaaaaatcag aagaatattt
     3901 ctgaagaagt tttaaaaaaa tctttattta aaacatttca gaatttagga ttagatgata
     3961 tgtataactt ttcttcagat ttccaactaa ttgaaggatt gataactcat ctaatgacac
     4021 tacaagtacg tttagaaagc cggattacct taaataaccc tttggtagat gaaattaaac
     4081 agaattatag tgatatattc tttatgacta gagaaattct tgcaaatatg gacaagttct
     4141 tggagtggac aatatcagat gatgaagtag catatgtaag tcttcacttt ttagctgcta
     4201 tggaacgtag caaagagagt actaagttta atattcttgc tatttgtgca acaggatttg
     4261 gtgcagccca aatgttaaga aatcgtttgg aaacggagtt tgggaagcga gtagaagttg
     4321 ttgatgtaat aggctattat gaattgaatc aagaaaaact taaaggaata gattttatag
     4381 tgtcagctgt tgatttatca aatctatatt ttcaaattcc agtttttaaa gttagtgtgt
     4441 ttcttaagag tgatgagatg gaaatgatta gaaaagctat ggatcagatg caagtttcta
     4501 gttatgtaca atcatcaaag attaataaat ttgaaaacaa cagctttaga cagtatttta
     4561 gtaaagaaaa ttttttaata tgtactgaat cagacaaggt aaatttactt gaaaagatgg
     4621 ttgagagttt atctgttggt gaatcaaatg agtttgaaca atctttactt tatggaatta
     4681 aacagcgcga agaattaagt tcagttgttt tttctgaaaa aattgcagtt ccgcatccta
     4741 ttcagccctt tggtacagag ggaaaggttt cggttgcaat ctgtaaagat tcgttactct
     4801 gggataatca aagttcatat gtccagctag tatttcttct atctccatca atatatggga
     4861 acgaaggttt ggcaactgtg actaaaaaga tagtctctct gacagagaat gatgagttgc
     4921 aaaatcagct aatatcttgc aataactttg aagattttat tagcatattt gagaagataa
     4981 aataggaggt tcatatgaat caagaggaac tgcaggttgc agcatttgaa attatcctgc
     5041 attcgggaaa tgcaaggtca gaaatacatg aagcatttgc aaaaatgaga gaaggtagtt
     5101 ttgatgatgc agaaagtaaa ttaaatcaat caaatgagat aattcttgaa gcgcatcatg
     5161 cacaaaccaa actcttgcaa gaatacgcaa gtggagtgga aattaaaatt gaaattatca
     5221 tggtacatgc tcaagatcat ttaatgacca ctatgacatt attagaagta gcaaaggaaa
     5281 tgttagctct ttataagaaa gttaactaaa tatgtgttgt tatataagga ggaaatgata
     5341 tggataaaaa agaacgacaa aagattgaac aacaacgtcg agagatggct ctaactaata
     5401 ctttttttaa tcgatatctt cttctacgtt attcaatagc actcttcttt tttgggaata
     5461 tttattggct tttgaatcag tttattaatc cctcgcctat tattattttc cccattatgc
     5521 tcatagtatt ttctatttta gcaactgttg aacaatttaa actctatgga aataggaaag
     5581 aaaagttggg aataacacta atgtttgtta gaatacaaat acttatttca ataggattac
     5641 ttgttttaac ttggacaagt tggtttaaga atctttttcc gatttttgaa aataaccaag
     5701 tagcacgttt atttgttttt gtagttcttc tattaggttt agttctgagt ttgttagaca
     5761 ttagaagaat taaaaaaatt tataaacgaa cagataaggc ttatcaacaa tttgtccaat
     5821 tggaaaagaa ctcacttagt ttataatcct gatctagtat aatttgtatt tgaaactagt
     5881 ctttagaaag taaaaattat tatgttttat taaggaggtc tatttatgga tcaacaaaac
     5941 gggttgtttg gttttcttga aaaccatgtt atgggaccaa tgggcaaact tgctcagttt
     6001 aaagtagtgc gtgctatcac ggctgcaggt atggctgctg taccatttac tattgtagga
     6061 tcaatgtttt tggtattcag tattttgcca caagctttct cattttggcc aattgtggca
     6121 gatattttct ctgcttcatt tgataaattc acatcacttt acatggttgc aaactatgcg
     6181 actatgggtt ctctatctct ttatttcgtt ctatcacttg catatgaatt gacaaaaatt
     6241 tatgcagagg aagaagaact caatatgaat cctcttaatg gtgccttgct cgccttgatg
     6301 gcttttgtca tgacagtacc gcaaatcatt tttgatggtg gaatgatgaa gactgtgaca
     6361 agtctaaaag aaggtgcagt aattgcagat ggatgggcaa tgggaaatgg agtcgcacgt
     6421 tttgggacaa cagggatttt taccgcaatc attatggcaa ttgtgactgt tcttatttat
     6481 cgtatgtgtg ttaaacataa ttgggttatt aaaatgcctg aagctgttcc agaaggagtt
     6541 tctcgtggat ttaccgcttt ggttccggga tttgttgttg catttgttgt tatctttatc
     6601 aacggtcttc ttgtagcaat gggaacagat atttttaaag tcattgcaat tccatttggt
     6661 tttgtatcca atctgactaa ttcgtggatt ggtttaatga ttatttatct attgactcaa
     6721 ctactttgga ttgtaggtat ccacggtgcg aacattgttt ttgcatttgt tagtccaatt
     6781 gctcttgcta acatggctga aaatgctgct ggcgggcact tcgctgttgc aggtgaattt
     6841 tctaatatgt ttgtaattgc aggtggttct ggtgcaactt taggactatg tttatatatt
     6901 gcttttgcct ctaaatctga acagcttaaa gcaataggac gagcatctgt agttccagcc
     6961 ttatttaata ttaatgaacc attaattttt ggattaccta ttatctataa tccagccttg
     7021 gctataccat ttattttagc accaatggtt actgctacta tttattacgt agcgaattct
     7081 ctaaacttta ttaagccaat tatcgcacag gttccatggc caactccagt agggattgga
     7141 gctttcttag ggacagcaga tcttcgagct gtattagttg ctctagtatg tgcatttgca
     7201 gcattcttag tctatcttcc attcatccgt gtatatgatc aaaaattggt gaaagaagag
     7261 caaggtatct aataagtaaa aaagtatact cgatgataga atccatatag tttaaataat
     7321 gagtgttaat attagcagtg aagaggtctt tttaagatat tcttctctgc tttttcatat
     7381 tttttcgcta tgtagggtat gaagcaaaat agaaagtagt tcgaatagtt gataaacagg
     7441 aaactgctgt tatttaaaaa aaacaataaa gtaaagtatg ttatcgtaga atacgataca
     7501 atagtaaaaa agcaaaaaga atgcgtttta tatttgggtt tgaggtttat aaaataggat
     7561 aagcgtgctg aaaacttaga tatgacaaac aaaataaaat ttttaaaagc tacatagaaa
     7621 catggtataa tgtatctaaa ggaggtagca tatgtcctta gatatagata aagaaaagat
     7681 gacaatcatg ggaatagctt ttgaaaacag atccgttttt aagagtgttt ggtatgcttt
     7741 aagtacaaat atgattgaag gatggcgacc tacggttagt gatgttgaaa aattacgaga
     7801 tgaagctctt gctctgggga tgacttaatg aagcgcaact gttatgagtc ttatgactat
     7861 gttgatccgg ataatttata taccgatccg ggttcttcag ttctaagaaa taagcaggaa
     7921 ggaaaaaagc acgcgagctt gaatatcgta tgattgctag taagagtttg aaattattta
     7981 tcaatcctat cttagttaat agtttaaaag tagtttgttt cacaactgca taagcttaga
     8041 aaagttgaaa agtgataact ctttaataaa ctcttggttt gttaaaagat attttgtcca
     8101 ctacattttt tcaattgact attatttgtc atagatataa cagatagaac agatagaaca
     8161 ttgcattcag aataatgaaa aacgcatcaa aaatggtgcg ttctgttttt atgctaccat
     8221 aaaaggagga aaacaaattg aaaattttta agggagagtt ttatcgaatc tctgtattaa
     8281 cagacaagct agtaaggtta gaatactctc aaactggaag ttttgaggat agaacgacac
     8341 aacttatcta taatagagat tttggccaag tttcgttaga ttatatcgag acatcaaacg
     8401 tactagatat tatgacggac tattttcatc tgcactttaa taaaggagaa tttaacgccg
     8461 aaaatttatt tatagaatta aaaggaaatt ttgccgtata tggtagtcgc tggtattttg
     8521 gtgaatctat tgaaacgtta aaaggaacag ctcggactct ggataaggca gatggagcaa
     8581 tctcgttaga agatggaatt attagccgaa atggtatagc cttattggat gattctcaag
     8641 gatttatttg ggatgaacaa tctggttata ttgagagaga aaatcaaatt gacctgtatt
     8701 tctttgccta tgggcatgat tatagaggag caatcagaga cttttaccat ttgactggtt
     8761 caacaccctt gttgccaaga tatgctttag gcaattggtg gagtagatat tggccttata
     8821 cgtcggatga atacttggat ttaatagaca gatttgaaac agagaaaatt ccattatcta
     8881 tcggtgtgtt agatatggat tggcatataa ctgacattcc agctcgtttt ggaagtggct
     8941 ggacaggata tagttggaat agaaacttaa taccaaatcc agaacagtta ttgcaacaac
     9001 ttcatgatag aaagttaaaa ctctccttaa atgtccatcc tgctgatggg atacgggctt
     9061 atgaagaagc ttatcctcaa atcgcaaaac ggttggggtt aaatgtagaa ctagaagaac
     9121 ctgctatttt tgattttttt aatccctctt ttagggaagc ctactttaaa gatgttcatt
     9181 atgagctaga aaagcaggga gtagattttt ggtggattga ctggcaacaa gggacacaag
     9241 gtatgctaga tccactttgg cttttaaacc attatcacta tcaggatagt tgtaaaaatg
     9301 cagaaggtgg tttgatttta tcaagatatg caggtcctgg tagtcaccgc taccctgttg
     9361 gtttttcagg ggatactatt attagttgga attccttaag gtttcaaccc tattttacag
     9421 cgacagcatc taatatcggt tatagttggt ggagtcatga tatcggtgga catatgttgg
     9481 gggattatga cgaagagcta caaactagat ggctacagtt tggtgttttt agtccgatta
     9541 ctcgattaca tagttctaga agtcctttta atagtaaaga accttggttc ttttcagaaa
     9601 caacatctaa gattatgaag aaataccttc gtttgagaca tcagatgatt ccctatctat
     9661 ataccatgaa tgtaaagaca catgaggaag gtgccccatt aatcagtcca atctattatt
     9721 tctatccaga gaatgatgag agctataatg ttccaaacca atactttttt ggaacagaac
     9781 tgatggtggc tcccattgta gaaaagatgg atttgacatt ccaatctgca aaagtagatg
     9841 tatggttccc tgaaggtgaa tggtatgact tcttttcaga gaaaaaatac acaggtggtg
     9901 tgaagttaag tgtttatagg gacatctcga ctacgcctgt gtttgcaaaa agtggtgcaa
     9961 tcattccctt ggttggttct gagataggta tgggtgttga tttacctgag gttgtagatt
    10021 ggtatgtatt cccagggaaa caacattttt ttgaaatgct tgaagatcaa aatggtcaaa
    10081 gatataaaac aagattatca atcgattggg aaatgggaat ggtagagtta gcattacaag
    10141 gagattctag tatcgttcca agcaatagaa aacatagaat tcattttaaa ggaacgaatg
    10201 tgtctataat tgaattgcca aataagaatg atacagctaa atttgaatgg aaagataata
    10261 aaaggacatc tttaaatgac gaagttttta gactactaaa gacagcttct cttccatatg
    10321 aattaaaaga tagattgtta aatcaattca tcaatgcgaa aaactctcat gacttaatga
    10381 atatcttgca tcatcaggat aaggaattga gagggcgttt gttggaaatg atatttacta
    10441 gccaaaacta attgaaataa ttagaaagtc atttgtttag tgtatatgaa gattctgtat
    10501 ggtattcgtt atcactggtc acattgaaaa tgtgaaataa gcacctacaa catagacttt
    10561 acaacacttc atgtttcata tcatggggtg tttttctatt taagtcaaag cccatcaaaa
    10621 aatctcacta ttcatcaggt taaaggaaac ctaatcatag tgagattgtg aattatagta
    10681 gagtttgtat cgcctcttca atttgttttg ggtctgtttt tgaagaaaag cgttcaaaga
    10741 cttgcccatc tcgaccgatg agaaacttag cgaaattcca ttcgattcgt tttcctagtg
    10801 ggccggattt ctggtctttt aaccagacat agagagggtc tgcttcctta ccgttgacct
    10861 taatcttggc aaaacgtggg aaggtggttt gaaaatgtag gctacagaag gcgttgattt
    10921 cctctgcgct gccgggtgct tgtcccataa actgattgca agggaaatcc aatatttcga
    10981 agccctgatc ttgatagcgt tcatagagtt cttgaagtcc ctggtactgg ggcgttaaac
    11041 cacatccagt agcagtgttg acaatcaaga gaactttgcc acgatagcta tccaagggag
    11101 ttgcttggtt gttttggttc aaaacggaaa aatcataaag tgaagtcatg agggcctctt
    11161 ttctttttct acattgtaac agtttttact tttttcgtcg agtcggatgg aagatattgt
    11221 tgaagaataa gccttcaata tgatagaaac cgtttacaaa taactttaaa aatggtatga
    11281 tttaattaaa ccggtttact tagttgctat aaatctctaa tttgagattt agttcctatt
    11341 gattttacaa tatgtttatt ggagtgtata catgcaaaca aaaacaaaga agctcattgt
    11401 gagtttgtct tcacttgttt tatcaggatt tttattaaac cattatatga cagttggagc
    11461 ggaagaaacg actacgaata ccattcagca aagccagaag gaagttcagt atcagcaaag
    11521 ggatacaaaa aatttagttg aaaatggtga ttttggtcag acggaggacg gaagcagtcc
    11581 gtggacagga agcaaagctc aggggtggtc agcttgggta gaccagaaga atagtgcaga
    11641 tgcctcaact cgagtcattg aggctaagga tggggctatc actatctcaa gccatgagaa
    11701 attaagggca gcggttcacc gtatggttcc tattgaagct aagaaaaagt ataaactgcg
    11761 tttcaagatt aaaacagatc ataaagtcgg gattgccaaa gttcgtatca ttgaggaaag
    11821 tgataaggac aagcgattgt ggaattctgc aacgacgtca ggaacaaagg actggcagac
    11881 cattgaagca gactatagcc cgactttaga tgttgataaa atcaagctgg agttattcta
    11941 tgaaacagga actgggactg tttcctttaa ggatattgag ctggtagagg tagcagacca
    12001 gccttctgag gactatcaaa cagataaaca gcttgaggaa aagattgatt taccaattgg
    12061 aaaaaaacat gttttttctc ttgcggacta tacttataag gtagaaaatc ctgacgttgc
    12121 ttcagtcaaa aatggaattt tagaacctct taaggaaggg acaaccaatg tcattgtcag
    12181 taaagatggc aaggaagtga aaaagattcc tttgaagatt ctagcctctg ttaaggatgc
    12241 atacacagac cgtttggatg actggaatgg catcatcgct gggaatcaat actatgattc
    12301 taaaaatgaa cagatggcca aattaaacca ggaattggaa ggaaaggtag ctgatagcct
    12361 atctagtatt tcaagtcagg cggaccgcac ctatttgtgg gaaaaatttt caaattataa
    12421 aatgtctgca aatctgactg ccacttatcg gaaattggag gagatggcca agcaagtgac
    12481 caatccttct tctcgttatt atcaagatga aactgtcgtt cgaacagtca gggattccat
    12541 ggaatggatg cataaacatg tctacaatag tgaaaagagc attgttggga actggtggga
    12601 ttatgaaatc ggtacacctc gtgccatcaa caataccttg tctctgatga aagaatactt
    12661 ctctgatgag gaaattaaaa aatatacaga tgtgattgaa aaatttgtac cagatcccga
    12721 acatttccga aagacgactg ataacccatt taaggctcta ggtggaaact tagttgatat
    12781 gggaagagta aaagtaatag ctggtttact gcgtaaggat gatcaagaaa tttcttctac
    12841 cattcgctcg attgagcaag tgttcaagtt ggtagaccaa ggtgaaggtt tttatcaaga
    12901 tggatcctat atcgaccata ccaatgttgc ctatacgggt gcttatggga atgttttgat
    12961 tgatggcctg tctcaactgt tgccagtcat tcaaaagacc aagaatccaa tcgataaaga
    13021 taaaatgcaa accatgtacc actggattga taaatcgttt gctcctttgc tggtgaatgg
    13081 agagctgatg gatatgagtc gtggacgctc gatcagtcgt gcaaatagcg aggggcacgt
    13141 ggccgcagta gaagtactaa gagggattca ccgaatagcg gatatgtctg aaggagaaac
    13201 caaacaacgt ttgcagagtc ttgtgaagac cattgttcaa tcggatagtt attatgatgt
    13261 ctttaagaat ttgaagactt ataaggatat cagtttgatg caatccttgt taagtgatgc
    13321 aggagtcgca agtgttccaa gaacaagtta cctatctgcc tttaacaaga tggataaaac
    13381 agccatgtac aatgcagaga aagggtttgg atttggcttg tcactctttt ccagtcgtac
    13441 cttgaattac gaacacatga acaaggaaaa taaacgtggt tggtatacga gtgatgggat
    13501 gttctatctt tacaatggcg atttgagtca ctatagcgat ggctactggc caacagttaa
    13561 tccatataag atgcctggta caacagagac ggatgctaag agagcggata gcgatacagg
    13621 taaagtttta ccgtctgctt tcgttggaac gagcaaacta gatgatgcca atgcgacagc
    13681 aaccatggat ttcaccaact ggaatcaaac attgactgct cataagagct ggtttatgct
    13741 aaaggataag atcgcctttt taggaagcaa tatccaaaac acttcaacag atactgctgc
    13801 aactacaatt gaccagagaa aactggaatc aagtaatcca tataaagtct atgtcaatga
    13861 taaagaagcc tcccttacag aacaagaaaa ggattatcct gaaacccaaa gtgtcttttt
    13921 agaatcatcc gattcgaaaa agaatattgg ttactttttc tttaagaaga gttcaatcag
    13981 tatgagtaag gctttgcaaa agggagcctg gaaggatatc aatgaaggac agtcagacaa
    14041 ggaagttgaa aatgaatttc ttacgattag tcaggctcat aagcaaaatg gagattctta
    14101 tggctatatg ctcatcccta acgtgggtcg tgccaccttc aatcaaatga taaaagagtt
    14161 agaaagtagc ctcatcgaaa ataacgaaac ccttcagtct gtttatgatg ccaaacaagg
    14221 agtttggggc attgtgaaat atgatgattc tgtctctact atttccaacc aattccaagt
    14281 tttgaaacgt ggagtctata ccattcgaaa agaaggggat gaatataaga ttgcctacta
    14341 taatcctgaa acccaggaat cagctccaga tcaggaagtc tttaaaaagc tagagcaagc
    14401 agctcagcca caagtacaga attcaaaaga aaaggaaaaa tctgaagagg aaaagaacca
    14461 ttcggatcaa aagaatctcc ctcagacagg agaaggtcag tcaatcttgg caagtctagg
    14521 gttcttgcta cttggggcgt tttatttatt ccgtagagga aagaacaact aatttgttca
    14581 tcatctagat gaattacatg aaactgtgga aaatagaaaa aatccgaaga aggccaaata
    14641 tcttcggatt tttcttttaa aaaaggataa gttgatactt atccttttta cttcattatg
    14701 tgactatagc gttttgaaac tagaatagga catcataact gctaaaagat ttctataaat
    14761 tcatttgatt ttcctaatca atttattcgt atcctatttc actctactat attagtccgt
    14821 ctcgcacctc acggagcgag acaaaacaac cacccgctat gcgggtgcgc gtcgaaggtt
    14881 ataccaaaaa aactccaaac gcgatacaat aaaggtgttc aatccacttg taaagcgaaa
    14941 ggagaaaaaa tatggcacaa aaggctcata gtttatctca cacaaagtgg aggtgttcta
    15001 tcacattgtg ttcaccccta agtatagacg aaaagtcatc tataatcaat atagaagtag
    15061 tttaggcgaa atatttcatc gcttgtgtag ttataaaggt gttgaaatga tcgagggtca
    15121 cttaatgcca gaccatgtac acatgttagt cagtattcca ctaaggctaa gtgtttcgag
    15181 tttcatgggt tatttaaaag gaaaaagtgc actcatgatg tttgacaaac acgccaatct
    15241 caagtacaag tttgggaatc ggcatttctg ggtggaaggt tattatgtaa gtccagtagg
    15301 gcttaatgaa gccacaatta agaaatatag tcaagattaa agaaattatc cagtggatga
    15361 tttcttcacg agtatgaaaa tttgagaact agtaaagtat gatatatagt aaaatgaaat
    15421 aagaacagga caaaatcgat caggacagtc aaatcgattt ttaacaatgt tttagaagta
    15481 gaggtatact attccagttt caatctacta tagcactaga taaattgagt gtaaaagaat
    15541 atgaggatcc ctttagggat agtggtaagt aataccaaag tctcttaaag aggcaagtga
    15601 cgagtcaaga gcaataaggc ttgaacaacg taaaagccag cgtctttagg cgctggctga
    15661 tgatttgggc ttatagctct gggataaacc acccgttaga cgggtagtta tgattttatc
    15721 tgagtgtaat atactgttgg gcaatctcgc tgatgcggtc aaagttgcct tgggaagcga
    15781 gtttattgag ttcgccacca attccaacgg catctgcacc agcagcgaac cattgaggga
    15841 tgttgtttag gccgactcct ccggttacca ttacggaaac ttgtgggatc ggtgccttga
    15901 ctgcagagat atatgctgga ctgagagtac tacctgggaa gagtttgatg atttcactac
    15961 cggcttcaag tgcagtcgtg atctctgtga gggtaataca gcctggaatg tacggtgtgc
    16021 tgtagagatt gcacattttc gcagtttcag catggaaaga tggagaaaca acgtaatttg
    16081 ctccagctag aatggcatct ctagcagtta cggcatcaag cacagtacct gcaccgatac
    16141 aaacactctg atcgtcctga tacaagtcta caagttcctt gatgatttgt cctgcatact
    16201 gattggtata ggcgatttca atagctttga taccgccctt gatacaagca atcgaggctt
    16261 gtagtccttc ttcctttgta tttcctcgaa tgacagcgac aattttctgt ttttttagtt
    16321 caataatcgt atctgatttg gtcatgtaat tctcctaacg aatgatatct tgtgcatttg
    16381 ccagtaaatt ttcaatacta gttgcggaag tggagagatg gtctcctgga agagtgcatt
    16441 tgagagttgc gctcgcaact gcaaagtcaa tggtagtttt tagggaggaa tgatggagta
    16501 gttggtaaag ggcaccagat ataaaggcat ccccgctacc aattcgttga tagactgcag
    16561 tttttagttg gacagactct tcaaatcgtt cttccagagc ataggcttga tagacatttt
    16621 tgtcttgctc atcactagat cggagggtat ggaaaatggc cttgaaacca taggcttctt
    16681 ttaaaagtcg catgcgattt tccacctctt ctaggctagc actgtctctt ggaaacatct
    16741 ctagattttg gtcatcaatc atgagaggat caataccgaa gcaatagtca gtaaaacgtg
    16801 caaacttaga aaattcatac ttggcttcta ggactgaaat catctttgtt ctcagattga
    16861 gatccattga aacgacaatt cctcggcgct tggcttcttc caagagtagg agaaggatcg
    16921 cacggacctc ttgaccgata gctatggtga ttccactaaa atgaaaatgg ctaatcccct
    16981 gaaagagaga atccatatct agcatgtttg gccgaatctg gctgatactc gtatgcttac
    17041 gatcgtagaa aacttcactt tgacgacaac caaagccgtt ctccaaatag tagaggccga
    17101 ttcgatcgcc aagccgacag attgaactgg tatcgatttg gtgctgtttc aagaatgtga
    17161 gaaaacgatc tccaatctcg ttggcaggga gtgcggtaaa gactttcgtt gagataccca
    17221 gggcttgcaa attacaagcg atgttaattt ctgatccgcc aaaataagtc gaactggcaa
    17281 catgatcgcc gatactggtg gcatctaatg gtgagattcg aattaatggt tcgccaaaca
    17341 gtaatatttt cgtcatccat tagttccttt ctggtttaga atagctttac ttggctaata
    17401 cttctttcaa ataagcagcg acttcatcat cttggcagtt ttcaaagaag tattcttgga
    17461 agtatttgcc agagatggtg tctttgagga agtcttggtc gattgtttta aggatggtca
    17521 tcaaatcatt gtgggtgatt tgtttcacct cgtttaagat acgagcgttg cgttgttcag
    17581 ggattacacg ttctcttggg tagccaccgc ccatttcttc agcaaataag cgttcaaaca
    17641 tcaatttgag ggtcagttct gccccccagc caaatccttt ggcataaggg atagacaagg
    17701 cgttaccacc attgatttga gaataaaggt aagcgtcagt tgggtccact gctagaccac
    17761 agacaacacc agggaagctg tttaaagcaa gcatagcccc tacacccgta ccacagccgg
    17821 taacaacaaa gtcaactgcc tttgtattta aaaggatggc agccattagt ccgttctgca
    17881 cataagttaa ttgactttct ccttcttctc cacgcatacc atagttaaat aattggtagt
    17941 cttttttatc tgtcgcttct tttagactat cgtaaataat gtgattcttg ctagcttgac
    18001 tattttcatt gattaatgcg attttcataa gatcttcttt ctatttttac tcaggttgtt
    18061 ttccgatgta ggctaagata ccgccatcta catataggat gtggccattg acaaaattgc
    18121 tggcatcact agcgagaaag acagcagggc ccatcaaatc ttcaggattt ccccaacgtg
    18181 cagcaggtgt ttttgcaatg atgaactggt caaatgggtg gcgagaacca tcttcttgca
    18241 actcacgaag aggtgctgtt tgaggagtgg caatataacc cggtccaatt ccgttacatt
    18301 ggatattggc tccaccgtat tcagacgcaa tgttgcgggt caacattttc aagccccctt
    18361 tagcagcagc ataagcgcta actgtttcac gtcccagttc gctcatcatc gaacaaatat
    18421 tgataatctt tccatgccct ttctttatca tagaaggaat aactgccttt gaaacgataa
    18481 atggtgcgtt taagtcaata tcgatgacct tacggaaatc agcggcgctc atttcgcaca
    18541 ttggaactcg gcggataata ccagcgttat taacgaggat gtcaatgaca ccaacctctt
    18601 gttcgatttg cttgaccatg gcttggatac cgtcctcgtc tgtcacgtca cagacatatc
    18661 catgggcttc gatgccaact tcacgataag cttcaatccc tttattgacc agatcttgat
    18721 tgatatcgtt aaagacaata gtagcgccgg cttcagcgta ggatttggca atagcaaatc
    18781 caattccata agaagcgccg gtgatgagag caatttttcc ttttaaagaa aactgctcaa
    18841 ttgagaatga tgtatttgtc atttgatact tcctttcaaa tttgttaaga cttctctata
    18901 accaaat
//
LOCUS       DBJKQU010000042        18226 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.042, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000042 DBJKQU010000000
VERSION     DBJKQU010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.042"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            315..1361
                     /gene="pheS"
                     /locus_tag="ACSUUC_001585"
     CDS             315..1361
                     /gene="pheS"
                     /locus_tag="ACSUUC_001585"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HHQ8054768.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1361..1870
                     /locus_tag="ACSUUC_001586"
     CDS             1361..1870
                     /locus_tag="ACSUUC_001586"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8054769.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GIGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1947..4352
                     /gene="pheT"
                     /locus_tag="ACSUUC_001587"
     CDS             1947..4352
                     /gene="pheT"
                     /locus_tag="ACSUUC_001587"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HHQ8054770.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDK
                     APYYAARILENVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDN
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAASSLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4420..5421)
                     /locus_tag="ACSUUC_001588"
     CDS             complement(4420..5421)
                     /locus_tag="ACSUUC_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HHQ8054771.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5577..6024
                     /locus_tag="ACSUUC_001589"
                     /pseudo
     CDS             5577..6024
                     /locus_tag="ACSUUC_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6150..6416
                     /locus_tag="ACSUUC_001590"
     CDS             6150..6416
                     /locus_tag="ACSUUC_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHQ8054772.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            6677..8926
                     /gene="metE"
                     /locus_tag="ACSUUC_001591"
     CDS             6677..8926
                     /gene="metE"
                     /locus_tag="ACSUUC_001591"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HHQ8054773.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATCIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8990..9856
                     /gene="metF"
                     /locus_tag="ACSUUC_001592"
     CDS             8990..9856
                     /gene="metF"
                     /locus_tag="ACSUUC_001592"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HHQ8054774.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(10038..10307)
                     /locus_tag="ACSUUC_001593"
     CDS             complement(10038..10307)
                     /locus_tag="ACSUUC_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine methyltransferase"
                     /protein_id="HHQ8054775.1"
                     /translation="MLGSLSFFLRNETKIQLLKMLSRQATQRKIGNRTTERLLLGRFI
                     FFHRVVGKFSFQDTSLERFNIKVSKPFTLIAIGRLAKCFTNSFVK"
     gene            10541..12754
                     /gene="pnp"
                     /locus_tag="ACSUUC_001594"
     CDS             10541..12754
                     /gene="pnp"
                     /locus_tag="ACSUUC_001594"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HHQ8054776.1"
                     /translation="MAKQVFQTTFVGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELITFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            12770..13387
                     /gene="cysE"
                     /locus_tag="ACSUUC_001595"
     CDS             12770..13387
                     /gene="cysE"
                     /locus_tag="ACSUUC_001595"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HHQ8054777.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13399..14283
                     /locus_tag="ACSUUC_001596"
     CDS             13399..14283
                     /locus_tag="ACSUUC_001596"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8054778.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFEREIASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14365..15708
                     /gene="cysS"
                     /locus_tag="ACSUUC_001597"
     CDS             14365..15708
                     /gene="cysS"
                     /locus_tag="ACSUUC_001597"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HHQ8054779.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMTKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLAAQGIKLLDTKDGVRWTRD"
     gene            15701..16087
                     /locus_tag="ACSUUC_001598"
     CDS             15701..16087
                     /locus_tag="ACSUUC_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HHQ8054780.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16091..16975
                     /locus_tag="ACSUUC_001599"
     CDS             16091..16975
                     /locus_tag="ACSUUC_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHQ8054781.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17217..17816
                     /locus_tag="ACSUUC_001600"
     CDS             17217..17816
                     /locus_tag="ACSUUC_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054782.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYAPLNDVTKYAR"
     gene            17959..18129
                     /locus_tag="ACSUUC_001601"
                     /pseudo
     CDS             17959..18129
                     /locus_tag="ACSUUC_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
BASE COUNT         5510 a         3508 c         4127 g         5081 t
ORIGIN      
        1 cgctataaag ttagataaga ataagctaac aagcagaagt aagataggtc ttgcaagaat
       61 ggtaaaaatc tgataaacta agtagtaatt gaataggaat ctgaaagact agtagcccaa
      121 gggaagtata tcagggagga gagccgtgac tgcaagctct ctatatgaaa gctgggtgaa
      181 ttcacttgcg catggattta gaaatgaagg tctgacttgt cagatgaaaa cggatggtac
      241 cgcgtgtcaa cgctccgagt ggagtttttg gcatgtggtt ttctttttat ctacgagaga
      301 ctgatggagg aaatatgtca actattgaag aacaattaaa agcgcttcgc gaagaaacgc
      361 tggctagctt gaagcagatt actgctggaa atgaaaaaga gatgcaagat ttgcgtgtct
      421 ctgtccttgg taaaaagggt tcgctcactg aaatcctcaa agggatgaaa gatgtttctg
      481 ctgagatgcg tccaatcatc gggaaacacg tcaatgaagc tcgtgatgtc ttgactgctg
      541 cttttgaaga aacagctaag ctcttggaag aaaagaaagt cgcggctcaa ctggctagcg
      601 agagtatcga tgtgacgctt ccaggtcgtc cagttgcgac tggtcaccgt cacgttttga
      661 cacaaaccag tgaagaaatc gaagatatct tcatcggtat gggttatcaa gtcgtggatg
      721 gttttgaagt agagcaagac tactataact ttgaacgtat gaaccttcca aaagaccacc
      781 cagctcgtga tatgcaggat actttctata tcactgaaga aatcttgctc cgtacccaca
      841 cgtctccagt tcaggcgcgt gctatggatg cccatgattt ttctaaaggt cctttgaaga
      901 tgatctcgcc agggcgtgtc ttccgtcgcg atacggacga tgcgacccac agtcaccaat
      961 tccaccaaat cgaaggcttg gtagttggga aaaatatctc tatggctgat cttcaaggaa
     1021 cgcttcagtt gattgtccaa aaaatgtttg gtgaagagcg tcaaattcgt ttgcgtccat
     1081 cttacttccc attcacagag ccatctgttg aggtggatgt ttcttgcttc aagtgtggtg
     1141 gagaaggctg taacgtatgt aagaaaacag gttggatcga aattatggga gccggtatgg
     1201 ttcacccacg tgtccttgaa atgagtggta tcgatgcgac tgtatactct ggttttgcct
     1261 ttggtcttgg acaagagcgt gtagctatgc tccgttatgg aatcaacgat atccgtggat
     1321 tctaccaagg agatgtccgc ttctcagaac agtttaaata atgattagaa aagtagaaat
     1381 ggcagatgtt gaggtgttgg ctaaaattgc caaacaagcc tttcgtgaaa cctttgcgta
     1441 tgataatacg gaagagcagt tacaggaata ctttgaagag gcttatagtc tgaaaacttt
     1501 gtcaactgag ttgggaaatc ctgactctga aacctatttc attatgcatg aggaggagat
     1561 agctggtttt ctcaaagtca actggggaag tgctcaaact gagagagaat tagaggacgc
     1621 ttttgaaatt caacgcctct atgtgctaca aaaattccaa ggatttggaa taggtaagca
     1681 actgtttgaa ttcgcacttg aacttgctac aaaaaatagt ttttcttggg cttggctagg
     1741 tgtttgggag cataatacaa aagctcaagc gttttataat cgatatggtt ttgaaaaatt
     1801 tagccaacat cattttatgg ttggtcaaaa agtagatacg gattggttac tgagaaagaa
     1861 attaaggtaa gaagaggatt cttctattga aatgatagga aaggaaaaga accagtgtgg
     1921 caatggtcat tctggagaac taaattatgc ttgtatctta taaatggtta aaagaattgg
     1981 tggacattga tgtgccatca caggagttgg ctgaaaaaat gtcaaccaca gggatcgagg
     2041 tagagagtgt cgaatcacca gctgctgatc tctcaaaaat tgttgtcggt gaggtcttgt
     2101 cttgcgaaga tgtgccagag actcacctcc atgtttgtca ggttaacgtt ggcgaagaag
     2161 aagcccgtca gatcgtttgt ggtgccccaa atgtgcgtgc tgggatcaag gtcatggtgg
     2221 ctcttccagg agctcgtatc gctgataact acaaaatcaa aaaaggaaaa atccgtggtt
     2281 tggagtcact tggaatgatc tgttcacttg gtgaattggg gatttctgac tcagttgtgc
     2341 ctaaggaatt cgcagatggc atccaaatct tgcctgaaga tgccgtgcca ggtgaggaag
     2401 tcttttctta cctagacttg gatgatgaaa tcatcgaact ttccatcaca ccaaaccgtg
     2461 cagatgccct ttctatgtgt ggagtggctc acgaagtggc agccatctat gacaaggcag
     2521 tcaactttaa agaatttact ctaacagaaa ctaatgaagc tgcggcagat gccctttctg
     2581 tcagcattga gacagacaag gcgccttact atgcagctcg tatcttggaa aatgtgacca
     2641 tcgcaccaag tccacaatgg ttgcaaaacc ttctcatgaa cgaaggcatc cgtcccatca
     2701 ataacgtagt ggacgtgacc aactacatcc tgctctattt tggtcaacca atgcatgcct
     2761 ttgacttgga taactttgaa gggactgaca tccgtgtgcg tgaagcgcgt gctggtgaaa
     2821 aattggtgac cttggacggt gaagaacgtg acttggacgt gaatgaccta gtcatcactg
     2881 tcgcagacaa gccagtagcc cttgcaggtg tcatgggtgg tcaagcaaca gaaatctctg
     2941 aaaaatctag tcgtgttgtc cttgaagctg ctgttttcaa tggcaaatct atccgtaaga
     3001 caagtggtcg cctgaacctt cgttctgagt catcttctcg ctttgaaaaa ggaattaatg
     3061 tggcaacagt taatgaagcc cttgatgcgg catctagcct gattgcggaa cttgcaggtg
     3121 cgacggtgcg taagggcatc gtttcagcgg gtgagcttga tacttcagat gtagaagttt
     3181 cttcaaccct tgctgatgtt aaccgtgtcc tcggaactga gctgtcttat gctgatgtag
     3241 aagacgtctt ccgtcgtctt ggctttggtc tttctggaaa tgcagacagc tttacagtca
     3301 gagtcccacg tcgtcgttgg gatatcacaa tcgaagctga cctttttgaa gaaattgctc
     3361 gtatctatgg ttatgaccgc ttgccaacta gtctaccaaa agacgatggt acagcaggtg
     3421 aattgacagc cacacaaaaa ctccgccgtc aagttcgtac tattgctgaa ggagcaggtt
     3481 tgacagaaat catcacctat gctctgacaa ctcctgaaaa agcagttgag tttacggctc
     3541 aaccaagtaa ccttactgaa ctcatgtggc caatgactgt ggatcgttca gtcctccgtc
     3601 aaaatatgat ttcaggtatc cttgataccg ttgcctacaa cgtggctcgt aagaataaaa
     3661 acttggctct ttacgagatt ggaaaagtct ttgaacaaac aggtaatcca aaagaagaac
     3721 ttccaaatga aatcaacagt tttgcctttg ccttgacagg cttggttgct gaaaaagatt
     3781 tccaaacagc agcagttcca gttgatttct tctatgctaa gggaatcctt gaagccctat
     3841 ttactcgttt gggactccaa gtaacctata cagcaacatc tgaaatcgct agccttcatc
     3901 caggtcgtac agccgtgatt tcactcggtg accaagttct tggtttcctt ggccaagtgc
     3961 atccagtcac tgccaaggct tacgatattc cagaaacgta tgtagctgag cttaaccttt
     4021 cagccatcga aggggcgctc caacctgctg ttccatttgt ggaaatcacg aaattcccag
     4081 cagtcagccg tgacgttgcc cttctcctca aggcagaagt gactcatcaa gaagttgtag
     4141 atgctatcca agctgccggc gtgaaacgtt tgacagatat caaactcttt gacgtcttct
     4201 caggtgagaa attgggactt ggtatgaagt caatggctta tagcttgacc ttccaaaatc
     4261 cagaagatag cttaacggac gaagaagtcg cacgctatat ggaaaaaatc caagcatcgc
     4321 tcgaagaaaa agtgaatgca gaagtgcgtt aaacgatagt atgatacaaa ttccccctct
     4381 agtttatgaa cactagaggg gtgattttat ataaaataat taaaatgtga tttctgtaaa
     4441 aatacatcta tgatcagagt tttgaaaact tacaatgtct aaatctttaa catagtagtg
     4501 gtttttaggc aataaaatat gatctattgt tgcattaaaa agttttggac tttggctatt
     4561 ccaagttcct ctttcaaaag gtggcagtac atttaatgcg tccctatgag agcttatttt
     4621 tgcaagtgct ccatgacgca tagttgcatt aaaatcacct gcaataatag cctttggata
     4681 ttttgaagcc aattgattat gaatgatgtt taagtcttgc ttccagattt ccattaaacc
     4741 tggcagagga ggagcagtat gcaaggcaat gatatctggt atattttgtt ttctcgaatg
     4801 taatacaatt gtcccaaacc gtgttgtatg aaaagtttta gcttctgtat agaaaccata
     4861 acttttcttg acaatcacag tcacaggagc tattccacta ttggtaggtg gagaagtgaa
     4921 aatatcatag ttggccatag aaagtccaac ttgatgaaac aatagtttga ttctctggtt
     4981 ttcttgctca cctctgatat tggtagctag ttcagggaat atagccatat cggcatcaaa
     5041 atggctaaaa attcgctcaa tatgttgtgc ttctatttga ttagcgacgt tccaagttac
     5101 taattttaag gttttagtct tatttgatgc agaagaaagg gttttatctg ttccgaataa
     5161 tagtaatatg agcgatagta agagcaaaat gccagagtaa aaccgtattt gtttattttt
     5221 cttgtaaaaa gatagggaaa aaaatacgaa acttaaaata gaagccatag ttgcagtagc
     5281 taaggggaag gcataaatct gtgccaagat aggtctggta gatagccaaa tattaagatt
     5341 agaagatgga aaaaaagaat aagctatgat agggataaca aagagaatga ccgaaagggc
     5401 agagagaaat gttttaatca ttgtgtgagt acctcaattt gcaatggttg ctcggagcta
     5461 atgtgacttt gtgactttac ttgattgata ttctttttat tgtcttcctt atagattaag
     5521 tacaacccaa gtaaaaaaag tccaatttaa gattgaaatg attaaaaggc acagagatgc
     5581 aagacaatta tactacaaaa ggtaaacatt tgacaatcga tagccgtcgc ttaatcgaaa
     5641 gatggaaaaa agaaggaaaa tcaaatagag aagttgcctc tctacttgga aaagctcctc
     5701 aaactatcca cactgaaatc aagcgtggga cagtccgaca atgtcttgga aaagggcgct
     5761 tcaaagaggt ttattctgcc gactacgctc aacagtctta tgaaaacaat cgcaagcgct
     5821 cggtcaagaa atcaagcttg accaaggaac taaaggaaaa gattctccac tatacataat
     5881 caaaaatttt cgcctgaaat gatggtgatg gctaaagggg ttaacgtggg aatttcaacc
     5941 atttactatt ggattcatcg tggaaaattg gggttaagca agcaggatct gctttatcct
     6001 agaaaaggaa aatcgcttaa gaaataggct agcaccaact ttaaacccgc tggtcaatct
     6061 atcgaatcat aattcgctca tttttttaaa aatacataga cgtaaaaaaa agagggttaa
     6121 gtgatgaaga atagtgctat tgggagtaat tggaaggatg tccatctgag ctctttagca
     6181 aggaggaaat ccttgaaagt gatatgcgag tggctatcat gagcgagttg attgaggcta
     6241 ggtatgaaca aggaatcagt cagaaaaagc tggaagaagt cagtggaata agccagcctg
     6301 tcatagctag gatggagaca ggaaagacta gtcctcagtt ggatacagtc ttaaaagtcc
     6361 tagccagttt aggaaagaca ctagcaatcg tcccacttga acagggaaaa agttgactag
     6421 aatcagttat agtcttttct aataacaagc catagtcact tataagaatt actaataacg
     6481 cgtttgagca ttctaactaa aatacagcta taaaacaagc tatacaaagg atttgagacg
     6541 tttgcttcaa gtctttttct tttgtccgaa acagatatat agtttcaaac tatatcaaac
     6601 cctaattttt tacaattata cagacgcttt cttttctgtt aagatagttt caacaacaaa
     6661 ttttggagga cacatcatgt caactacaat catcggtttc cctcgtttgg gcgaattccg
     6721 tgaattaaaa tttacaactg aaaaatactt tagaaaagaa atctcagaag aagaactttt
     6781 agcagcagca aaagacttgc gtgctaaaca ctggaacatt gtcaaagaaa aaggcatcac
     6841 tgaaattcca tcaaatgact tttctcacta tgataacttc ctagatgcgg ctttcctttt
     6901 caacgtggtg cctgcatctg ttcaaaactt ggacttgtct gaccttgagc gctacttcgc
     6961 tttgggacgt ggttaccagg gagaaaaagg ggacgttcgc gcccttccaa tgaagaaatg
     7021 gttcaacact aactaccact acatcgttcc taaatttgaa aaagacactc aagtgaaatt
     7081 ggctggtcac aagattttcg atgagttcca agaagcaaaa gaacttggat tgaacactcg
     7141 tccagttctt gtaggtccct tcactttcct tcaattgtca gactttgaag aaggcgtgaa
     7201 agcagacgac ttcgtagata gcttagtggc tgcttaccaa gaagtttttg ctaaattggc
     7261 tgaacttggt gcgacttgca tccaattgga tgaagcggct cttgtaaaag acttgacagc
     7321 tgaagaaaaa gctctcttct tgaaccttta caacaaactc ttggctgaca aaaaaggtct
     7381 tgaagtcttg cttcaaactt atttcggtga tgttcgtgac gtatacgctg accttgtaaa
     7441 cttaccagta gatgctatcg gtcttgactt tgttgaaggt aagaaaactc ttgaactcgt
     7501 taaaggtggc ttcccagctg acaagactct ctatgtaggt attgtcaatg gtaaaaacat
     7561 ctggcgcaac aactacgaaa agagcttggc tgttcttgag caaattccag ctgaaaacat
     7621 cgttttgaca agctcttgct cacttcttca tgtgccattt acaactgcta atgaagaatt
     7681 tgaaccagca ctcttgaacc actttgcctt tgcagttgaa aaattggatg aaatccgtga
     7741 cttggatgct atccgcaatg gtcaaggttc agaagctctt gcagccaaca aagaactctt
     7801 tgcgactgag cgtgttggtg aaaatgctga acttcgtgcg cgtatcgctg gcttgacaga
     7861 cgcagactac actcgtttgc cagcctttgc agaacgtgaa gctatccaag aagaagcttt
     7921 caaacttcca gctcttccaa caacaacgat tggttcattc cctcaaacaa aagaagttcg
     7981 tgccaaacgt ttggcttacc gtaaaggtga attgtctcaa aaagagtacg atgctttcct
     8041 tgctgaaacg attgacgaat ggatcaagtg gcaagaagat attgactttg atgtccttgt
     8101 tcacggtgaa tttgagcgta atgacatggt tgagtacttc ggtcaaaact tgtcaggata
     8161 cctcttctct aaaaatggat gggtacaatc atacggtatg cgtggggtaa aaccaccaat
     8221 catctggggt gatgtcactc gtcttaaccc tatcactgtt aaatggtcta gctatgcaca
     8281 aagtcgtaca aacaaacctg ttaaaggtat gttgactgga cctgttacca tccttaactg
     8341 gtcattccca cgtgaagaca tctctatcaa ggattcaact ctccaaatcg cccttgctat
     8401 caaggatgaa gtacttgacc ttgaagctgc tggtgtgaaa atcatccaaa tcgacgaggc
     8461 tgctcttcgt gaaaaattgc cactccgccg tagcgactgg tacgaagact accttgactg
     8521 ggctattcct gccttccgct tggtacactc aacagtagcg ccagacacac aaatccacac
     8581 tcacatgtgt tactcagaat ttacagatat catcccagct atcgataaca tggatgcaga
     8641 cgttatttcc tttgaagcta gccgttcaaa ccttgaaatc ttggacgaac tcaaagcgaa
     8701 aaacttccaa acagaagtgg gacctggggt ttacgatatc cactcacctc gtgtaccaaa
     8761 tgaaggcgaa atcgacaaca caatcgaagc catccttgct aaagtgccaa gcaagaaagt
     8821 ttggatcaac cctgactgtg gtttgaaaac acgtggtatc ccagaaacaa aagaaagctt
     8881 gatccgcctt gttgaagcag ctaaagctgc gcgtgagaaa ttgtaagatt ggatttctct
     8941 ccatacagtg gttgttcaaa aagaaatcaa ctagaaaagg ttattacata tgtcacgcca
     9001 aacaccgtca ctctcatttg aagtgttccc tccaaaccca gccgtgggta atggtaacat
     9061 tatttcagcc ttgcaggata tgcaggagtt ggctccccat tttatcagtg taactgccag
     9121 caataataaa tttaatatca aggaaacgac ggttcgtttg gctgacttta tccaaaatga
     9181 tttggcgatt ccgaccattg cccacttgcc agctatttat ctaactaagg acaaggttgc
     9241 tgaaactatt gctgacttgg acaaagttgg ggtgcagaaa atcttggctc ttcgtgggga
     9301 tattattcca gacgtggaac cacaaaagga tttccgctat gcaaccgact tgattgagtt
     9361 tatcaaggaa caaacccctc actttgatat tattggagct tgctatccag aagggcatcc
     9421 agattcgcca aatcagattt cagatattca aaatcttaag aagaaagtgg atgcaggctg
     9481 ttcgagcctc gtaactcagc tcttctttga caatgagcgc ttctatgatt ttcaggacaa
     9541 gtgcatcttg gctgggattg atgttcccat tcatgcagga attatgccaa ttctgaatcg
     9601 aaatcaggct ctccgactct tgaagacttg tgagaatatc catcttccac gcaaatttaa
     9661 agccatctta gacaagtatg agcatgaccc tgagtcgctc agagcagcag gacttgccta
     9721 tgcagtggac caaatcgtgg acttggtaac tcaggatgtt gccggtgtgc atctctatac
     9781 gatgaataat gctgatacag caaaatacat ccatcaagca acccatgcct tgtttaatca
     9841 ccagtctcta ggataataaa agcaaaccat tcttctcagg tgaggggaat ggttcctttt
     9901 taatggcaaa gacctcactt tttaagaaaa atatgataaa atagattctg tacgtacttg
     9961 atacaaagat gaaggtatta aataatacaa tgcatttaaa ctgtaagatt taacgacacg
    10021 agtgagtcaa atcgatgtta tttgacgaaa gagttagtaa agcatttagc taatcgcccg
    10081 atagcaatta gcgtgaaagg tttagatact ttaatattaa acctttctaa tgatgtatct
    10141 tgaaaactga acttgcctac aactctgtgg aaaaagataa atctccctag gagcagtcgc
    10201 tccgtcgttc gatttcctat cttcctttga gttgcttgac ggcttagcat cttgagtaat
    10261 tgaattttgg tctcatttct taggaaaaaa gataagcttc ctagcactcg tcgagtgcga
    10321 cgtcaccttc ctatttttct acagaaatgt tcggcaagcc gaaccgtcca aaatatcttg
    10381 tgtaattgaa cacggccgaa aagctgtgta aaaaagataa actgtcttgt cttcatcgaa
    10441 gacttcgtca gtttcctatt tttactttgc ttttgacgtc cttggtatct tgatctttgt
    10501 aggcaaggcg tataatttca tcaatccaaa ggggattaaa atggcaaaac aagtgtttca
    10561 aacgactttt gtgggtcgtg agttaattgt agagactggt caggttgcta agcaagcaaa
    10621 tggctctgtt gtcgtacgtt acggtgagtc aactgtcttg actgctgccg ttatgtctaa
    10681 gaaaatggca actggggatt tcttcccact ccaagtcaac tacgaagaaa aaatgtatgc
    10741 ggctgggaag tttcctggtg gctttatgaa acgtgaagga cgtccttcaa cagatgcgac
    10801 cttgacagcg cgtttgattg accgtccgat tcgtcctatg tttgcggaag gtttccgtaa
    10861 tgaagtccaa gtcatcaata cagtgctttc ttatgatgaa aatgcatctg caccaatggc
    10921 tgctatgttt ggttcatctt tggcactgtc tatttcagat attccatttg acggaccaat
    10981 tgctggggta caagtgggat atgtagatgg ccaaatcatc atcaacccaa gtcaagaaca
    11041 agcagagcaa tctcttcttg aattgacagt agctggaacc aagcacgcta tcaacatggt
    11101 agagtctggt gccaaagaat tgtcagaaga aatcatgttg gaagcgcttc ttaaagggca
    11161 cgaagctgtc aaagaattga ttaccttcca agaagaaatc gttgctgctg tcggtaaaga
    11221 aaaagcagaa gtggaattgc ttcacgtgga tgctgaattg caagctgaaa tcattgcagc
    11281 ctacaacagt gacctccaaa aggcagttca agtagaagag aaattggccc gtgaagctgc
    11341 aactcaagca gtgaaagacc aagtgactgc cgtttacgaa gaaaaatatg cgaaccacga
    11401 agaatttgac cgtattatgc gtgatgtggc tgaaatcttg gaacaaatgg aacacgcaga
    11461 agtgcgacgt ttaattacag aagacaaggt gcgtcctgat ggtcgtaagg tcgatgaaat
    11521 ccgtcctttg gatgcggttg ttgacttcct tcctcgtgta catggttcag gtctctttac
    11581 tcgtgggcaa actcaagctc tttcagtctt gaccttggct ccgatgggag aaactcaaat
    11641 cattgatggt ttggatccag agtacaagaa acgctttatg caccactata acttccctca
    11701 atattctgta ggggaaacag gtcgttacgg tgcgccaggt cgtcgtgaaa tcggtcacgg
    11761 tgctcttggt gagcgtgctc ttgctcaagt cttgccaagc ttggaagaat tcccatacgc
    11821 tatccgtcta gtagcagaag ttttggaatc aaacggttct tcatctcaag cttctatctg
    11881 tgcgggaact cttgccctta tggctggtgg tgtgccaatc aaggcgccag tagctggtat
    11941 tgctatggga cttatctcag atggaaataa ctacacagta ttgacagata tccaaggttt
    12001 ggaagatcac tttggagata tggacttcaa ggttgcaggt actcgtgatg ggattacagc
    12061 ccttcaaatg gatatcaaga ttcaagggat tactgcagaa atcttgacgg aggctcttgc
    12121 tcaagccaag aaagcgcgtt ttgaaatcct tgatgtcatt gaagcaacca ttccagaagt
    12181 tcgtccagaa ttggctccaa ctgctccgaa aattgatacg atcaagattg atgtggacaa
    12241 gattaagatt gtcatcggta agggtggaga aaccatcgac aagattatcg ctgaaacagg
    12301 tgttaagatt gatatagacg aagaaggaaa tgtgtctatc tactctagtg accaagatgc
    12361 tattaaccgt gccaaagaaa ttattgctgg tttggttcgt gaagccaaag tggatgaagt
    12421 ttaccgtgct aaagtcgttc gtatcgagaa atttggtgcc tttgttaacc tctttgataa
    12481 gacagatgcc cttgttcata tctctgagat ggcttggact cgtaccaatc gtgtagagga
    12541 tttggtagaa atcggggatg aagttgatgt taaggttatc aagattgatg aaaaaggccg
    12601 tatcgatgcc tctatgaagg ctcttctacc tcgtccgcca aaacctgagc atgatgaaaa
    12661 aggtgaaaag tctgagcgcc ctcaccgccc acgtcatcaa aaggatcaca aacctaagaa
    12721 agaatttaca gaaacaccaa aagattcaga ataagaaaag gagaaatgta tggggtggtg
    12781 gcgcgaaacc attgatattg taaaagaaaa tgatccagcg gcccgcacca ctttggaggt
    12841 tttgctgact tatccaggtg tcaaggcctt ggcggcccac cgtctctcgc attttctctg
    12901 gaagcacggc ttcaaactat tagctcgtat gtacagtcag ttttggcgct tttggactca
    12961 gattgagatt catccaggag cccagattga ttcaggtgtt tttattgacc atggttctgg
    13021 tctggtgatt ggagagacag cgattgttga aaaaggcgtt cttctctatc acggagtgac
    13081 tctcggggga acagggaaag actgtggcaa acgccatccg actgtacgaa agggagccct
    13141 catatcagcc catgcccaag ttatcgggcc tgtggaaatt ggtgaaaatg ccaaggtcgg
    13201 tgctgcagca gttgtcgtag cagatgtacc tagtgacgtg acggttgtcg gtattccggc
    13261 caagattgtc cgtcttcatg gtaagaaaga tgagcctgtc attcacgaag tcgaagaaaa
    13321 acgagagtat tatgtcaata aactcgagca ggctaaagat gccagtcaca gatcgtctgg
    13381 tttgtagagg atacctatat gattcaagca agaaacaagt taagccaaga ggagctatct
    13441 gaggcgaaaa aagtaattaa ctgttgccaa aactatgacg gtacctatcg cgatccctat
    13501 ctctctaaca tgcttaattt tgacccaaac atgcccgcct ttttccttta ttatgaaaaa
    13561 ggcgaacttg ttggtttatt aactgtctat gcagatgacc aagatgtaga agtaacgata
    13621 ctggttcatc caggtcatcg ccgtcagggg attgcgcgtg cattgtttac tagttttgag
    13681 agagaaatag cttctttccc cattcggtca gtcacttttc agacagaacg tattttttta
    13741 gagaatcatc ctgactttgc cagtaactgg ggactaatcg aggatgaaga gacagaaact
    13801 tggttaggta aggatagaag accttatccg ttagcaaatg tttcccatct tgaagttttg
    13861 ttagcagata gttcgtatca ggatcaaatt agtcaattaa aatttcaggc attttcagag
    13921 gaacatgaat cgagagaagt tgtggataga tatgtcgctg aagctctgaa ggatccagaa
    13981 agtcgcttat atattttgtt aaaagacggt caggttattg ggacttgcac ggtagattta
    14041 tcgactaata cgaattactt ctacggttta gcaatatcgg aacctgaacg tgggaaaggc
    14101 tatggaagct acttagcaaa atccctcgtc aaccaactaa ttgagcaaaa tgacaaggaa
    14161 tttcagattg cagtggaaga tagcaatgta ggtgccaaac gtttgtatga aaaaattggc
    14221 tttgtcaaac agactcaggt ggtttatctg aatgagaaag gagcaaggga ttccgaagtg
    14281 tagagatatt cggactgaaa tttacttgaa cttttagtga tgaaactaat tgttcttgga
    14341 tttcagcttt cctgattatg atttatgatt aaaatctatg acaccatgtc tcgtgatttg
    14401 cgagaatttg tcccgattga ggacggcaag atcaagatgt atgtttgtgg gccaacggtg
    14461 tacaactata tccacgtggg aaacgcccgt tcgacggtag cttttgatac gattcgtcgc
    14521 tattttgagt accgtgggta taaggttgcc tatatttcca attttacaga tgtggatgat
    14581 aagattatca accgtgccag ggaagaaggt atcacgcctc aggaggttgc ggataagtac
    14641 atcgctgcct ttcgtgagga tgtgacggcc ttaggcgtga aacctgcgac tcgccatccg
    14701 cgtgtagtgg agtttatggc agacatcatc cgttttgtgg aagacttgat cgagaaaggc
    14761 tttgcctatg agagtcaagg ggatgtctat ttccgtgtag aaaaatccca caactatgcc
    14821 aaattggcta ataaaacctt ggaagatttg gatctaggtg cttcaggtcg taccgatgaa
    14881 gaaacggctc gtaaggaaaa tcctgtagat tttgctctat ggaaatcttc caaaccaggt
    14941 gagatttctt gggatagtcc ttggggacct ggacgtccgg gttggcacat tgagtgttca
    15001 gtcatgtcga cagagatttt aggtgatacc attgatatcc acggtggtgg agctgaccta
    15061 gaatttccgc accacaccaa tgaaattgcc caatctgaag ctaaaacagg caaggctttt
    15121 gctaactact ggatgcacaa tggctttgtc aatatcgaca atgtcaaaat gtctaagtcc
    15181 ttgggtaact tcattacggt acacgatgcc cttaaaactc ttgatgggca agtacttcgt
    15241 ttcttctttg cgacccagca ctaccgtaag cctatcaact tcacggaaaa ggcagttcgc
    15301 gatgccgaga ccaatctcaa gtatctgaag aatacttacg aacaaccatt tacaggaaac
    15361 gtggatgccc aagagttaca aaactttaaa gataagtttg tagcagctat ggatgaagat
    15421 tttaatgctg ccaacggtat cacagttgtc tttgaaatga ccaaatggat caactcaggg
    15481 aactatgatg caagtgtcaa gcaagctctt gcagatatgt tagaaatttt tggaattgtc
    15541 tttgttgagg aagttttgga tgcagagatt gaagacttga ttcaaaaacg ccaagaggcg
    15601 cgtgccaatc gagactttga gacagcagac caaatccgtg accaactggc tgctcaaggc
    15661 attaaactat tggatacaaa agatggagtg aggtggacac gtgattgatg tcaatctcat
    15721 taacgggatt gcgctagcct ttgagggaga tgcggtgtat tctatgtata ttcgccgcca
    15781 cctcatcctc aaaggtatga ccaaacccaa taaactccat caagaagcaa ccaagtatgt
    15841 gtcagccaag gctcaggctc gcctgattgc tctcatgttg gaggagcagg tcctaacgga
    15901 aaaagaagaa gaaatctaca aacgtggccg caataccaat agccacacaa aggctaaaaa
    15961 tgcagatgtc gtgacttatc gtatgtccac gggatttgaa gcggttatgg gctatctcca
    16021 tatgactgag aatctggaac gtcttgagag tttggtttca tggtgcatcc aaaaagtgga
    16081 gggctagaac atgagggaaa aagaactaca agactggttt cctgaggctc ggatttcaga
    16141 ccaaccagta gagaaagagg gctatctcac gctcccttta gcttctcagc agtggatttt
    16201 gctggaggaa gctgggctca gcgagcgtga aaagcagttg gttgcccttt tgacccagca
    16261 ggagcaggct cgttcgctaa acccttggta ttcctatctg gttgaaggca agggacaggc
    16321 accgcaagtt tttaaaaaga ttcagttggt ttattgccat ctttcttatt ttcagcagga
    16381 aaatctgact tcttggctag atatgatgcg gactcttttt ccgaattgtc agacagtgct
    16441 acaggtcgga gctcaggatt atgttttcgt gcttcaacaa gacaaataca cttctgtaag
    16501 agatatttta agtgatacga ttgaagcggt tgagtatgat tttggacttc gtctttctat
    16561 catgttgggt caggtttggt ctcagacagg acatcaagcc ctatcagact taatcaaagc
    16621 tgagcgggat ttgttcaaga catggtggcg tcagggtcac caaggtgttc atactttttc
    16681 tcagctctat ctttggagta tgggagaaag actcgtggac ttgaagccaa ttaaagaatg
    16741 tctacaccag atgattttgg atcaagatca gattcaggaa atcattctct ctctttggga
    16801 aaatagtgct gttctcacta aaacagccca gcaactctat ctgcaccgca attctctcca
    16861 atacaagatt gataaatggg aagagttgac agggcttcag ttgaaagagt tgaccgacct
    16921 gaccttgtgt tatcaattga ttttaggttc tttgtcaact atagttggtt tgtaaagaag
    16981 ttaatatttg gagaagagga ttgccatctt ctccattttt atgtgcagag ttatagtggc
    17041 ttgatgctgg gaaagtacac tgtgactgat aatactcaat gaaaatcaaa gtacaaacta
    17101 ggaagctagc cgcaggctgt acttgagtac gtcaaggtga agctgacgtg gtttgaagag
    17161 attttcgaag agtataaaac attcctagaa gttgctttga tttccctaat ctatttatgc
    17221 aaattttatg ttattttact ataacagttg ttgctaagcc aaataatagt ggggaagttc
    17281 atttagacgt aagcattgaa gataatcagg gaggtagtgg gcataatttc agttctgttt
    17341 caagtagctc acaaacagct aaatatgaag aaactggtta taataacaat tcatcattat
    17401 atacaacgat tgataaaacg tctgatgcaa cagctctttt gaaattaaag ttgaataatg
    17461 ttgataatca acctgctact gaagttccta gttcaggaat tactgtaaaa ttaaatgcta
    17521 aagataatgc tggaaactgg acaagtgctt cgaataaaaa agaaataaca gtaaaaattg
    17581 tttctgctaa accgacatat ccagacaaaa tcttagtgaa aaatcctgat aatataaaag
    17641 atacagaaaa aaatgccatt attgaaaaat tgaaagaggc aaataaaaat catccagcag
    17701 gagctccaac ctttgctaaa ggtgaaggag agcatgcaaa tgatattgta gcaacttatt
    17761 cagatggtac aacttattat gcaccgttaa atgatgtgac aaaatatgcg aggtagtggc
    17821 tgtaccactc acttattcac ctccccgtga tttgtagtag tgataggctt tctcactatt
    17881 attataaaac aaaataaaga tcacaacact ttttcattct gtgttgtgcc ttgagtgaaa
    17941 cgaaaggaat gaattataaa tatgaaaagt atagtcacta gcatagatga gcgcttgcgt
    18001 actcgcctac gagtgattat ctggaagcaa tggaagaaga aatcgagacg attatgggga
    18061 ttgcttaagt taggggttcc taaatggata gcagataagg tatctggctg gggcgaccac
    18121 tatcaattat attaaaatga aataagaata ggacgaatcg atcagggaag tcaaatcgat
    18181 ttctaacaat attttagaag tagaggtata ttattctagt ttcaat
//
LOCUS       DBJKQU010000043        17748 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.043, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000043 DBJKQU010000000
VERSION     DBJKQU010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17748
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.043"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..225
                     /locus_tag="ACSUUC_001602"
     CDS             <1..225
                     /locus_tag="ACSUUC_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054783.1"
                     /translation="TTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKA
                     GYLFSVLLLFSNFSVPFIKEKEFELFKNSK"
     gene            704..910
                     /locus_tag="ACSUUC_001603"
     CDS             704..910
                     /locus_tag="ACSUUC_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054784.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLAPLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFFYKE"
     gene            1326..1865
                     /locus_tag="ACSUUC_001604"
     CDS             1326..1865
                     /locus_tag="ACSUUC_001604"
                     /inference="COORDINATES: protein motif:HMM:NF037419.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HHQ8054785.1"
                     /translation="MLFYFEKIWSLSLKLLDCILDYQERFNGKTCQVSTNYKYLEIFK
                     VNFCLTDLHHLFGLHKITRDYASQTKPAIQTGVFILEDFRNILLYNDVIERISLYEFI
                     SDIFYSKITSCCIVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFT
                     SAKKYAKVRKTDVKEMKWL"
     gene            2164..4116
                     /gene="pspA"
                     /locus_tag="ACSUUC_001605"
     CDS             2164..4116
                     /gene="pspA"
                     /locus_tag="ACSUUC_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HHQ8054786.1"
                     /translation="MILTSLASVAILGAGFVTSSPTFVRAEEAPVASQSKAEKDYDAA
                     KKDAKNAKKAVEDAQKALDDAKAAQKKYDEDQKKTEKKAAAVKKIDEEHQAANLKSQQ
                     ALVEFLAAQREGNPKKKKAAQAKLEEAEKAEKEKKKEFDKAQAVVVPEATELAETKKK
                     ADEAKVKEPELTKKLEEAKAKSEEAEKKATEAKQKVDAEHAKEVVPQAKIAELENEVQ
                     KLEKDLKEIDESDSEDYVKEGLRAPLQSELDAKQAKLSKLEELSDKIDELDAEIAKLE
                     KNVEDFKNSNGEQAEQYRAAAEEDLAAKQAELEKTEADLKKAVNEPEKPAPAPETPAP
                     EAPAEQPKPAPAPQPAPAPKPEKPAEQPKAEKTDDQQAEEDYARRSEEEYNRLTQQQP
                     PKAEKPAPAPKPEQPAPAPKIGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGS
                     MVTGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGAMATGWLQNNDSWYYLNAS
                     GAMATGWAKVNGSWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWVKVNGSWYYLN
                     ANGAMATGWVKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWY
                     YVNGLGALAVNTTVDGYKVNANGEWV"
     gene            4517..5638
                     /gene="mnmA"
                     /locus_tag="ACSUUC_001606"
     CDS             4517..5638
                     /gene="mnmA"
                     /locus_tag="ACSUUC_001606"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HHQ8054787.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            5779..6234
                     /locus_tag="ACSUUC_001607"
     CDS             5779..6234
                     /locus_tag="ACSUUC_001607"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHQ8054788.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEYAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            6244..8157
                     /gene="mnmG"
                     /locus_tag="ACSUUC_001608"
     CDS             6244..8157
                     /gene="mnmG"
                     /locus_tag="ACSUUC_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HHQ8054789.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMINEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(8491..10170)
                     /gene="rnjA"
                     /locus_tag="ACSUUC_001609"
     CDS             complement(8491..10170)
                     /gene="rnjA"
                     /locus_tag="ACSUUC_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J1"
                     /protein_id="HHQ8054790.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAIKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(10172..10405)
                     /locus_tag="ACSUUC_001610"
     CDS             complement(10172..10405)
                     /locus_tag="ACSUUC_001610"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HHQ8054791.1"
                     /translation="MIYKVFYQETKERSPRRETTRTLYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            10685..10900
                     /locus_tag="ACSUUC_001611"
                     /pseudo
     CDS             10685..10900
                     /locus_tag="ACSUUC_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11223..11375)
                     /gene="cibB"
                     /locus_tag="ACSUUC_001612"
     CDS             complement(11223..11375)
                     /gene="cibB"
                     /locus_tag="ACSUUC_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HHQ8054792.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(11378..11564)
                     /gene="cibA"
                     /locus_tag="ACSUUC_001613"
                     /pseudo
     CDS             complement(11378..11564)
                     /gene="cibA"
                     /locus_tag="ACSUUC_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
     gene            11741..12424
                     /gene="tsaB"
                     /locus_tag="ACSUUC_001614"
     CDS             11741..12424
                     /gene="tsaB"
                     /locus_tag="ACSUUC_001614"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HHQ8054793.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVAPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEAESLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            12421..12858
                     /gene="rimI"
                     /locus_tag="ACSUUC_001615"
     CDS             12421..12858
                     /gene="rimI"
                     /locus_tag="ACSUUC_001615"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 - protein-N-terminal-alanine
                     acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HHQ8054794.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            12848..13858
                     /gene="tsaD"
                     /locus_tag="ACSUUC_001616"
     CDS             12848..13858
                     /gene="tsaD"
                     /locus_tag="ACSUUC_001616"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HHQ8054795.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGESYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVLDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEVTDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(13898..15203)
                     /locus_tag="ACSUUC_001617"
                     /pseudo
     CDS             complement(13898..15203)
                     /locus_tag="ACSUUC_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(15539..16248)
                     /locus_tag="ACSUUC_001618"
                     /pseudo
     CDS             complement(15539..16248)
                     /locus_tag="ACSUUC_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16491..17357
                     /locus_tag="ACSUUC_001619"
     CDS             16491..17357
                     /locus_tag="ACSUUC_001619"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024831.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HHQ8054796.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCIPNN
                     KKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICYLKCRD
                     NFRLLGEIYPVL"
     gene            17411..17695
                     /locus_tag="ACSUUC_001620"
     CDS             17411..17695
                     /locus_tag="ACSUUC_001620"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHQ8054797.1"
                     /translation="MCVLESMSQGTPVLASNVGGLSEIIEHRVDGFLFEKEDVEGVCA
                     CANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYDELLEKSSHG"
     gene            17688..>17748
                     /locus_tag="ACSUUC_001621"
     CDS             17688..>17748
                     /locus_tag="ACSUUC_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHQ8054798.1"
                     /translation="MDRNIDQELVSIIIPTHNRY"
BASE COUNT         5441 a         3218 c         3981 g         5108 t
ORIGIN      
        1 actacgataa aatttttatt catcagatta tttgacacaa gtactttaat gaagaggaga
       61 atattttttc ttttcgcatt ggatgttata gcttacttat ttttaggata tcttttagtg
      121 attcaaaaag caggctattt gttttcggtt ttacttcttt tttctaattt ttcagttcca
      181 tttatcaaag aaaaggaatt cgaattattt aaaaatagca agtaatagaa acataggtta
      241 aatcttagaa cggcttaaaa tcagatatga taaagggaaa tagtcttatc taggtaacta
      301 agtgctacaa acacagtcga ggatcacttg ttaggattac attttaatca tgcttaataa
      361 gaatggagaa ttcctatggg gattgtatta ctctgaagtt tcgaatacct tagttctcgt
      421 gattttgagc tattctaggt ttagaatcct tcagaatgta aaattttaag cagtcaaaga
      481 cttagaatag cccgaaaaca tttattttat agcaattcta ggcttagaat tgctcatata
      541 tatgtatttg agctgctcga tagttaggac agctttattc tgagaaatct gagctatcaa
      601 tgcttcagaa tagtatttcg ccaatggttt ttattgaaga ggtgattgtt ttatgatagt
      661 ctaaaataaa actgatttaa tggagtaaat ggagaatcgt tacatgaaac atttttttgc
      721 aggaattggt gagataaaac ttgttggcta cttattgtat atatgtgtag gactagcccc
      781 tctttttcat atatatgtca taggttcgga actgagtttt gtgaaaatag tgttatctat
      841 tttgggagtt atatttgtaa gtatgttaac tattgctcga atttatagga cttttttcta
      901 taaagaatag tttggacttg aactgtatct aaaaacagag gttggtcgat tatcagcctc
      961 tttcttgtcg ttgaaaagag tgagatatat tgacttttga aaaaaagatg tcataattga
     1021 gttgggataa acctaaaagt aatatagtag attgaatctg gaatagtccg ttatgactgt
     1081 taaaatattt ctagaaatta atttgacttt cctaatcgat ttgttcacat cttgtttcaa
     1141 tctactatac tttctcgtta aaccgttcgg caattcatgg tgacatggac acatggtagt
     1201 aagcacacta tgtggcttgg cagagctaaa aactgttccc ttgcaataag cctaataagc
     1261 acaacatagg gagttagaga agccgactct aatcaaccac tttgggcaat agtgagaact
     1321 gccctgtgct tttttatttt gaaaaaatat ggagtttgtc gttgaaatta cttgattgta
     1381 ttttggacta tcaagaaaga ttcaatggaa aaacatgtca agtatcaacg aattataagt
     1441 atttagagat tttcaaagtg aatttttgct tgactgattt acatcattta tttggcttac
     1501 acaaaatcac acgagattat gctagtcaaa caaaacctgc tattcaaact ggtgttttta
     1561 ttttagaaga ttttagaaat atcctattgt acaatgatgt aatcgaaagg atatctttat
     1621 atgagtttat aagtgatatt ttctattcta aaataacaag ttgttgcatc gtagctaagg
     1681 atttatctaa aaatactatg aaattggacg tcatattttt tgaggataaa aataaaagat
     1741 ccgcagtttt aggtttacga agagataaaa gcggagtatt taaaccagtt actctacatt
     1801 ttacaagcgc taagaaatat gctaaagttc gtaaaacaga tgtgaaagaa atgaaatggc
     1861 tataaagatt gtccgcaggc ttaagcttgc gttttttgtt gtttaacgaa attaaaaaat
     1921 aagctctctc atcggaaatg tttttatagg aatgaaggaa gatgatgcta tgtttaaaaa
     1981 gagaatcgaa aagggcaaaa gtagtgtctt tatctttttg gagtagaagc ttatgatata
     2041 gaaattgtaa taaaaatgta atataaaaca tttgacaaat atttacggag ggagtatact
     2101 taatataagt atagtctaaa aatgactatc agaaaagagg taaatttaga tgaataagaa
     2161 aaaatgattt taacaagtct agccagcgtc gctatcttag gggctggttt tgttacgtct
     2221 tcgcctactt ttgtaagagc agaagaagct cccgtagcta gtcagtctaa agctgagaaa
     2281 gactatgatg cagcgaagaa agatgctaag aatgcgaaaa aagcagtaga agatgctcaa
     2341 aaggctttag atgacgcaaa agctgctcag aaaaaatatg acgaggatca gaagaaaact
     2401 gaaaagaaag ctgctgcggt aaagaaaatt gatgaagaac atcaggcggc taatcttaaa
     2461 tctcagcaag cattagttga attcttagct gctcaaagag aaggtaatcc taaaaagaaa
     2521 aaagctgcgc aagccaagtt agaagaagca gaaaaagcag aaaaggagaa gaaaaaggaa
     2581 tttgataaag cacaggcagt ggtagttcct gaagcaactg agttagctga gactaagaaa
     2641 aaagcagacg aagctaaagt aaaagaacca gaacttacta aaaaactaga agaagctaaa
     2701 gcaaaatcag aagaagctga gaaaaaagct actgaagcca aacaaaaagt ggatgcagaa
     2761 catgctaaag aagtcgttcc tcaagctaaa atcgctgagt tggaaaatga agttcagaaa
     2821 ctagaaaaag atctcaaaga gattgatgaa tctgactcag aagattatgt taaagaaggt
     2881 ctccgtgctc ctcttcaatc tgaattggat gccaaacaag ctaaactatc aaaacttgaa
     2941 gagttgagtg ataagattga tgagttagac gctgaaattg caaaacttga aaaaaatgta
     3001 gaagatttca aaaactcaaa cggtgagcaa gctgaacaat accgtgctgc agctgaagaa
     3061 gacttagctg ctaaacaagc tgaattagaa aaaactgaag ctgaccttaa gaaagcagtt
     3121 aatgagccag aaaaaccagc tccagctcca gaaactccag ccccagaagc accagctgaa
     3181 caaccaaaac cagcgccggc tcctcaacca gctcctgcac caaaaccaga gaagccagct
     3241 gaacaaccaa aagcagaaaa aacagatgat caacaagctg aagaagacta tgctcgtaga
     3301 tcagaagaag aatataaccg cttgactcaa cagcaaccgc caaaagcaga aaaaccagct
     3361 cccgcaccaa aaccagagca accagctcct gcaccaaaaa taggctggaa acaagaaaac
     3421 ggtatgtggt acttctacaa tactgatggt tcaatggcaa caggatggct ccaaaacaat
     3481 ggttcatggt actacctcaa cgctaatggt tcaatggtga caggatggct ccaaaacaat
     3541 ggttcatggt actacctcaa cgctaatggt tcaatggcga caggatggct ccaaaacaac
     3601 ggttcatggt attacctcaa cgctaatggt gctatggcga caggatggct ccaaaacaac
     3661 gattcatggt attacctaaa cgctagcggc gctatggcaa caggttgggc taaagtcaac
     3721 ggttcatggt actacctcaa cgctaatggt gctatggcta caggttggct ccaatacaac
     3781 ggttcatggt actacctcaa cgctaacggt gctatggcaa caggttgggt taaagtcaac
     3841 ggttcatggt actacctcaa cgctaacggt gctatggcaa caggttgggt taaagtcaac
     3901 ggttcatggt actacctcaa cgctaacggt tcaatggcaa caggttgggt gaaagatgga
     3961 gatacctggt actatcttga agcatcaggt gctatgaaag caagccaatg gttcaaagta
     4021 tcagataaat ggtactatgt caatggttta ggtgcccttg cagtcaacac aactgtagat
     4081 ggctataaag tcaatgccaa tggtgaatgg gtttaagccg attaaattaa atcatgttaa
     4141 gaacatttga cattttaatt ttgaaacaaa gataaggttc gattgaataa atttatgttc
     4201 gtattcttta ggtacctatc ttatgatttc aggaaatgtc attaaaaaaa cgactccttt
     4261 tctctaactt gaaaaataga ttagagaaaa tgggttgttt tatttattat agttatttga
     4321 atgaagataa gaagaaggta tactcacgtc attcacatga tctgtatatt gactataagt
     4381 tttaaaaaac aatttttaag ctcttccttg tcttctctaa ccaagcgtgt tataatgaat
     4441 actgctcaag cgaccttcaa tcgtgaagca cacacgacct tcaatcgtga ataaacgaat
     4501 agatgggaga cttaccatga gtgataactc taaaacacgt gttgtcgtgg ggatgagtgg
     4561 tggtgttgat tcgtcggtga cggctctttt gctcaaggag cagggctacg atgtgatcgg
     4621 tatcttcatg aagaactggg atgacacaga tgaaaacggc gtctgtacgg cgaccgaaga
     4681 ttacaaggat gtggttgcgg tggcagacca gattggcatt ccctactact ctgtcaattt
     4741 tgaaaaagag tactgggacc gcgtttttga gtatttccta gcggaatacc gtgcgggacg
     4801 cacgccaaat ccggacgtta tgtgcaacaa ggaaatcaag ttcaaggcct ttttggacta
     4861 tgctatgacc ttgggggcag actatgtagc gactgggcat tatgctcgag tggtgcgtga
     4921 tgaggatggt accgttcaca tgcttcgtgg cgtggacaat ggcaaggatc agacctattt
     4981 cctcagccaa ctttcgcaag aacaacttca aaaaacgatg ttcccactag gacatttgga
     5041 aaagcctgaa gttcgaaaac tagcagaaga agcaggtctt tcgactgcta agaagaaaga
     5101 ctcgacaggg atttgcttta tcggagaaaa gaactttaaa aactttctca gcaactacct
     5161 gccagctcag cctggtcgta tgatgactgt ggatggtcgc gatatgggcg agcatgcagg
     5221 tcttatgtac tatacaatcg gtcagcgtgg cggactcggt atcggtgggc aacacggtgg
     5281 tgacaatgcc ccttggttcg ttgtcggaaa agatctaagc aagaatattc tctatgtagg
     5341 acaaggattc taccatgact cgctcatgtc aactagccta gaagccagtc aagtccactt
     5401 tactcgtgaa atgccagaag agtttacgct agaatgtacg gctaaattcc gttaccgtca
     5461 gcctgactct aaggtgaccg tccatgtcaa aggagacaag gcagaagtta tctttgcaga
     5521 accacaacgc gcgattacac caggacaggc agttgtcttt tacgatggcg aagagtgtct
     5581 aggtggcggt ttgattgaca atgcttaccg cgatggacaa gtttgtcagt acatttagat
     5641 tgacaaattt tctcaatttg ctacaataat aacagcaata gaaatgatgg tcaaagctca
     5701 tggatgttgc aggctttttt gtcctgcact tctttgtagt tttgactgtt tttgtgtcgt
     5761 ttaagggaaa ggacaagaat gactcaacaa gactttcgga caaaagtaga caatacggtt
     5821 tttggtgttc gggctacagc cttgattgtc caaaatcaca agcttctagt taccaaagac
     5881 aagggcaagt attacactat tggaggtgcg attcaagtca atgaaagcac ggaatacgcg
     5941 gtagtccgtg aagtgaagga agaactgggt gtcaaagctc aagctgggca gctagctttt
     6001 gtggttgaaa atcgttttga acaagacggc gtttcctatc acaatatcga gtttcattat
     6061 ctggtggatt tgcttgaaga tgccccgttg accatgcagg aagatgagaa aaggcagccc
     6121 tgtgagtgga ttgacttgga taagcttgag gatatccagc tagttccagc ctttttaaaa
     6181 acggccctac cagattggga aggccaacta agacacattc atcttgaaga ataggagaga
     6241 aacatgactt atcattttac tgaagaatac gatattattg taattggtgc gggacacgct
     6301 ggggttgagg cttccttagc tgctagccgt atgggctgta aggtcctgct tgcgactatt
     6361 aacattgaaa tgctggcttt catgccttgt aatccctcta tcggtggttc tgctaagggg
     6421 attgtcgtac gtgaagtcga tgccctcggt ggcgagatgg ccaagaccat tgacaagact
     6481 tacatccaga tgaagatgct caacacaggg aaggggccag ctgtccgtgc tcttcgtgcg
     6541 caggctgaca aggaacttta ctctaaggag atgcgcaaga cagttgaaaa tcaagaaaat
     6601 ctgacccttc gtcaaaccat gattaatgag attttggtgg aagatggcaa ggttgtcggt
     6661 gtgcgtacag ccacccatca agaatatgct gctaaggctg ttattgtgac gacagggact
     6721 gctctccgtg gggaaattat catcggagac ctcaagtact catcaggtcc taaccacagc
     6781 ttggcttcta ttaacctagc tgacaatctc aaggaactgg gcctcgaaat cggtcgtttc
     6841 aagacaggaa cccctccacg tgtcaaggct tcttctatca attacgatgt gacagaaatc
     6901 caaccaggag atgaagcgcc taatcacttc tcatacactt cacgtgatga ggattatgtc
     6961 aaggaccaag tgccatgctg gttgacctac accaatggta ccagtcatga gattatccaa
     7021 aacaacctcc accgtgcgcc tatgtttaca ggtgtggtca agggagtggg gcctcgttac
     7081 tgtccgtcga ttgaagacaa gattgtgcgc tttgcggaca aggaacgcca ccaactcttc
     7141 cttgagccag aaggacgtaa tacagaggaa gtctatgtgc aaggcctctc aaccagtcta
     7201 cctgaggatg tccagcgtga cttggttcat tccattaaag gtttggaaaa tgcagagatg
     7261 atgcgaacag gttatgccat tgagtacgac atggtcttgc ctcatcagtt gcgtgcgact
     7321 ttggaaacca agaaaatctc aggtctcttc actgctggtc agacaaatgg aacatcaggt
     7381 tatgaagaag ctgctggcca agggattatc gcgggtatca atgcggcttt gaaaatccaa
     7441 ggcaagcctg aattgattct aaaacgaagt gacggttata tcggggtgat gatcgacgac
     7501 ttggtgacca agggaaccat tgaaccttac cgtctcttga ccagtcgtgc tgaatatcgt
     7561 ctcattcttc gccatgacaa tgctgatatg cgcttgactg agatgggacg cgagattggc
     7621 cttgtggacg atgaacgctg ggctcgtttt gaaatcaaga aaaatcaatt tgataatgag
     7681 atgaagcgcc tagacagtat caaactcaag ccagtcaagg aaaccaatgc taaggttgag
     7741 gaaatgggct tcaagccgtt gacagatgcg gtgacagcca aggaattcct tcgccgtcca
     7801 gaagtttctt accaagatgt ggtggccttc atcggaccag ctgcagagga attagatgac
     7861 aagattatcg aattgattga aacagaaatc aagtacgaag gttacatctc aaaagccatg
     7921 gatcaggttg ctaagatgaa gcgcatggaa gaaaaacgta ttccagccaa tatcgactgg
     7981 gatgacattg attctatcgc aaccgaagcc cgtcagaagt tcaaactcat caatccagaa
     8041 accatcggcc aagccagccg tatttcggga gtaaacccag cagatatttc tattttgatg
     8101 gtgtatctgg aaggtaaaaa tcgtagtatt tctaaaactc ttcaaaaatc aaaatgatat
     8161 gtcgtaggct tcttacgaat gagttcaaag cttggctttg attcatctcc aatctcccat
     8221 agttccccga actatgggag ctaactcaag ttatgcattt tcctagcctt ctggtctgat
     8281 tttcattgag ttttaatcta aaaagaaagc atagagaaaa acagctccga agacggggct
     8341 gttttgttga tttgtactca atgaaaatca aagagcaaac taggaagcta gccgtaggtt
     8401 gctcaaagca ctgctttgag gttgtggata gaactgacga agtcagtaac atatatacgg
     8461 caaggcgaag ctgacgtggt ttgaagagta ttattcttca tctggtgtga ggatcatcgg
     8521 gatgatgatc ggttcacgtt cggtattttc atagaggaag gggcgaatag cgttgacaat
     8581 ggcaccattg acagattgca cgctagcatc cttatttttc agtgcgatac gaatggcatt
     8641 gaagaggata cgctggcttt ggcgaatcaa gtctccagac tctctcatgt agacaaagcc
     8701 tcggctgagg atatctgggc cagacagaat catctgcgat ttgaagtcaa cagttgcgac
     8761 tgctagaacg acaccgtctt cagatagatc gcgacgatct ttgaggacag ctgcgccaat
     8821 ttcaccgata cgatttccat cgacatagat atcttgggcg ttgaaatgac ctgcgatacg
     8881 agctgagtca gcagtaaggg caagcacatc gccattgctc atgataaaga tattgtcctt
     8941 ctcaacacca gtatccactg ctagtccagc gtggactttt tgcatgcggt attcaccgtg
     9001 gacaggcatg aagtattttg gcttaatcaa gcggagcatg agtttttgct cttgctggcc
     9061 accgtgtcca gatgtatgga tattgttcac tttaccgtgg ataacttcga caccagcttc
     9121 agaaatgatg ttaatcagct tgttgacgct agtagtgttt ccagggatgg gactagaaga
     9181 gaagataacg gtatcacctg gttgtaattg tacttgacgg tgggttccgt tggcgatacg
     9241 agagagggct gccataggct caccctgact acctgtacag aggataagaa cttctcctgc
     9301 aggataatct ttgatttcat ttggctcgat aaaggttccc ttaggagctt tgatgtagcc
     9361 aagatcgatt ccgttgacaa tggccttttc catagaacga ccaaagaccg caatcttgcg
     9421 tccagtctta atagcagctt ctgttgcctg ctggagacgg aagatatttg aggcaaagga
     9481 tgcaaagatg atacgtcctt caataccttg gataatcttc ataatggact gaccaacgac
     9541 tttttcagag ttggtaaagg ttggtacttc cgcatttgtc gagtcagaca ggagacagag
     9601 cacgccttct tcaccaaggg cagccatacg atgcaagtcc gcaggttctc caactggagt
     9661 aaagtcgaac ttaaagtcac ccgtacagac gattttccct tgaggagtat gaatgacaat
     9721 ccccaaaggc tctggaatag agtgagtcgt tctaaagaaa gttgccttga gatttttaaa
     9781 ggtcaactcg gtgttgtggt tgatttcgta aagtttggcg ttgcgcaaga ggccgtgttc
     9841 ttcgagtttc ccacggatca aagccaaggc aagcggtcca gcgtagatag ggacatttgc
     9901 ttgcttgagt aggaacggaa tcccaccaat gtggtcctcg tgtccgtgtg tgattaaaac
     9961 agccttgacg cggtcgatat tgtccacgat gtaagagtag tcaggaatga catagtcgat
    10021 accaagcaag tcatcttctg ggaatttaat cccagcatcg acgatgataa tctcgtcttg
    10081 gtattcaatt ccgtaagtgt ttttcccgat ttctcctaga ccaccgatgg caaaaacgcc
    10141 gacttcttca ggtttaagag tgtaggccat attagaactc cgtaatttcg aaggcgccag
    10201 tttctttttc gtaatcgagc aatttgtcag acaagagttc gatatactcg atattgtact
    10261 ctgggcgatt ttcttcgaca agttggcgag cagtgatacg gccctcaagt tctgagctgg
    10321 catcgatgtc taggtaaagc gtgcgtgttg tttcacggcg tgggctacgt tcttttgttt
    10381 cttgataaaa aactttgtaa atcatatagt tcctttctat ttacaggtca gcttattcca
    10441 aacttttagc agatatttgc ttgatttcat tccattttgt gtctagattg accttgattc
    10501 gttacaatta tttcaattat accacaaaat gaaaaattag taaaagacgg aaacgagaaa
    10561 gttaggggac gatttctttg gtaagcgttt gcaaaaataa agaaaatgta ttatgttgat
    10621 aacggaagtg aaatttattg cttgtcataa ttccatatag attttaagtc aaggaggttg
    10681 ccctatgtat aacttatttg cttttgctat cggagctcgc ttggtagctt ttattgtttt
    10741 tgttgcttgc gtttatgcgg ggaatcttct atttgccaaa ctggaacgat gacaaaccaa
    10801 gttcttgtgg aaaattacct ttgtgactct ctactcgctt tttctcctcc tcgtgaccta
    10861 tgtcgtttgg tttgtatttt actttggatt aaatgcttag atgccctgct tatgctgggg
    10921 ttttttgttt ggggatgtag agatagtaga tttacgacac gaaaattcca ccccatctat
    10981 caagatgagg tggtctttgc atttttctaa catgacatga caatggaatt ttcaaagctt
    11041 attattttta tgggagtcat tgttctgctc aaaaatagag ttgaagcata aaaataaaac
    11101 aatacaaaca gataaatcga atggtaaagg gatagtagta atgttcaaat cattgagaat
    11161 gctgagcaaa ctgtaagaga tgaagacaat aaaatttatc cttctaaaaa tgtgtttctt
    11221 atctagcatg acttaccaaa ctttttacga aggtcttttc caatggtata acctgccata
    11281 aataaagcga taccaacacc tacaccaaag ccacccttga tttcttgcaa ttccttatta
    11341 gaaatttcac gatagttgtt caaatctttc atcatagtta atctcctcct aaaaaataac
    11401 cagctgccaa accagaacct ataagtgctg ttccacctgc aatagccttc caagatactg
    11461 ctactccaaa gataaccaag ggagcgagac cgccatcaat atctgataat tcattttcag
    11521 ataaggataa aaaattgatt gtcaagaatg tcaaaatttg tcattgaact ttcctccttt
    11581 tttcttgttc acttttatat tcggaaaaga aaaggaaaag tgagcatttt ttaaattatt
    11641 tttagttaag tgagggcact cttgtctggg ggcaaagaaa attcccatgt gccagctttt
    11701 gtagtataat agtaagcaga caaaaagata ggaatgtgtt atgaaagtat tagcttttga
    11761 tacgtccagc aaggctcttt ctctggctat tttagaggac aagcaggttc ttgctgagac
    11821 gacgattaat atcaagaaaa atcacagtat taccctcatg ccagccattg attttttgat
    11881 ggagagtttg gactggacgc ccaaggattt ggaccgaatc gtggtggcgg aagggccagg
    11941 tagctacaca ggcttgcgaa tcgcggtagc cactgccaag accttgactc atactctgaa
    12001 cattgagtta gttggtatgt ctagcctctt ggctctggtg ccatatcaac aagaaggctt
    12061 gttcgttcct ttgatggatg cgcgtcgcaa caatgtttat gcaggatttt atgaaaatgc
    12121 taaacctgtc atgccagaag cgcacctatc ttttgaagag gtgctagaaa aagtcaaggg
    12181 tgctagtcag gtaacctttg tcggagaagt tgcccccttt gtggagcaga ttcaagaaca
    12241 cttgccaagg actaattata aagaaacctt gcctaatgca gccaatcttg ctcttttagc
    12301 ttgggacaag gaagcagaat ccttgcatga ttttgtgcca aattacctca aacgagtcga
    12361 ggctgaggaa aactggctca agaaccatac cgagtctggt gagtcctaca ttaaacgcct
    12421 atgatagaaa tcaagcgaat tcaacaacag cctgacctag ctcaagccat ctacgctgtt
    12481 atggcagctg tttacctagt cagtccttgg actctggagc aaatccaagc agatctgtcc
    12541 caagaccaga cttggtatgc attggcttat gatggggcag aagtgattgg atttctagct
    12601 gtgcaggaga atctttttga agcagaagtc ctgcaaatcg ctgtcaaagg agcttatcag
    12661 ggtcagggaa ttgcgtcagc cttgtttgct caattgccga cagataagga gattttcctc
    12721 gaagtcagaa agtcaaatca acgagcgcaa gcattttaca agaaagaaaa aatggcggtc
    12781 atcgctgagc gaaaggccta ctaccatgac ccagtcgagg acgccattat catgaagaga
    12841 gaaatagatg aaggatagat atattttagc atttgagaca tcctgtgatg agaccagtgt
    12901 cgccgtcttg aaaaacgacg atgagctctt gtccaatgtc attgctagtc aaattgagag
    12961 tcacaaacgt tttggtggcg tagtgcccga agtagccagt cgtcaccatg tcgaggtcat
    13021 tacagcctgt atcgaggagg cattggcaga agcagggatt accgaagagg acgtgacagc
    13081 tgttgcggtt acctacggac caggcttggt cggagccttg ctagttggtt tgtcagctgc
    13141 caaggccttt gcttgggctc acggacttcc actgattcct gttaatcaca tggctgggca
    13201 cctcatggca gctcagagtg tggagccttt ggagtttccc ttgctagccc ttttagtcag
    13261 tggtgggcac acagagttgg tctatgtttc tgaggctggc gattacaaga ttgttgggga
    13321 aacgcgagat gacgcggttg gtgagtccta tgataaggtc ggtcgtgtca tgggcttgac
    13381 ctatcctgca ggtcgtgaga ttgacgagct ggctcatcag gggcaggata tttatgattt
    13441 cccccgtgcc atgattaagg aagataatct ggagttctcc ttctcaggtt tgaaatctgc
    13501 ctttatcaat cttcatcaca atgccgagca aaagggagaa agtctgtcta cagaggattt
    13561 gtgtgcttcc ttccaagcag ctgtactgga tattctcatg gcaaaaacca agaaggcttt
    13621 ggagaaatat cctgttaaaa ccctggttgt ggcaggtggt gtggcagcca ataaaggtct
    13681 cagagaacgc ctagcagccg aggttacaga tgtcaaggtc atcattccac ctctgcgcct
    13741 ctgcggagac aatgcaggta tgattgctta tgccagtgtc agcgagtgga acaaagaaaa
    13801 cttcgcaggc tgggacctca atgccaaacc aagtcttgcc tttgatacca tggaataaag
    13861 agtggctctt tgtcaagtgt agtgggtagg cgaaaagcta caatctggag agtacgaaat
    13921 tcgtactctc ttttttgatg ttcaaagtca tcaaaatccg ttttttaaaa ttgttaaagt
    13981 tccggaaacc aaaggttttg cgcttgataa ccttaatcaa attattggtc gcttcaagtt
    14041 tagcgttgga ataaggcagc ttaagtgcgt tgataatctt atctctatcc cttaaaaaag
    14101 tccaaaagac cgtttgaaaa agcggatgaa ccgttggcag ttcttgctca atcaatccaa
    14161 agaaatggtc ggcattcttc tcttgaaaat gaaagagcag gagttgatag agttcgtagt
    14221 gaacctgtaa tccctcagag taagaaagca gcttatctcg tacttcccga tgggttaagt
    14281 gcattgaaac gtgggctgat agaatcgttt ctgacagagc ttgaagctat cctggtgtag
    14341 taaatcagtc cagtggactg atttagcccg agcctagaaa cgaaaaagcg agggttccaa
    14401 aagcgcttga gcgcccgata ctctaaggat tttcggtcaa attggttcat gatttggatt
    14461 cgtactcggt tcatagctcg gctcagatgt tggacaatgt ggaagcggtc aagaacaatc
    14521 ttcgcctttg gaaagagttg cttagcgagc cgataataag ggctgtacat gtccatggtg
    14581 atgacctcga ccagctcccg aacctctctc tgatagcgtt ggaaatggtt tcgaatcacc
    14641 gcataagttc gcccgtctaa aattgcgagg atggatttgg actcaaaatc ttgggcaatg
    14701 aagctcattt tgctcttttt gaagctatac tcatcccaac tcataacttt tggcaacttg
    14761 gtccaatcgg tttcaaactt aaattccctc agttttcgga tgacggtgga agttgagacc
    14821 gccaatctgt gggcaatctc agtcatagac tgcttttcaa ggaggagctg agcgattttt
    14881 tgtctcacca tgttggaaat ctggcaattt ttcttgacaa tggatgtttg agaaacgacc
    14941 accttaaggc aattcttgca ctgaaagcgg cgctttttga gatgtagtac cgtgggtaaa
    15001 ccctgacagt cgagaagcgg aattttagag gctttctgga aggcgtattt gatcatcttc
    15061 ccttgacaat gaggacaagg aggagcgggg gaatccaact ttgcctgaac gactagatgg
    15121 gtttggtatt tcagaacaga caagattttg atatttttgt ctttcaatcc gagcaaatct
    15181 gtggtattct taagttgttc catatgaacc ctttctaatg agttggttag acgcttttca
    15241 ttataggtca tatggggctt tttttctaca agaaacgacc ctataattcc tggggtggga
    15301 ttacccacta cagaaattat agagccaaaa cattccaaag tcttgtctga ctctggaatg
    15361 ttttctgttc acagttgttt tgtaactgcc taataagtaa ccgcgctata acgaggtatc
    15421 taccgagatt gtcaattctc cagtatactg ttataaaaaa caaaactgga ggattttttt
    15481 atgtcccccc atcgtcccat cgactgttcc gtagctgccc aataacggag catagtcggc
    15541 tgaaacaaga ataggacaaa agtgcctcaa gaaaagcatc gtaatttgac aatattattc
    15601 tgagatgttt ttgatgtaag cccatatttt ctcaatggga ttatactcgg gtgaataggt
    15661 aggaagtggt aacagtctat gccctgctcc ttacacatgt tcattctgtg aaaccttgca
    15721 ttgtccataa tgataaggga tggtgtatct aaagtaggta gtaagaattt ttggaagcaa
    15781 gcttcgaaaa agtcactcgt catcgtatct ttataggtca tcgtatcttt ataggtcatc
    15841 ggagccatag tatattgaaa caaaaaaggg cattagtact tctataacag tatcgcaatc
    15901 tctggtgtgc gttgtctcga tcttaattca aataattata tcttcttcca gagagactaa
    15961 ctgcctgctc aaggctcgat catattcgag ataaaaatag gtctcaaccc ctgtctcata
    16021 aatataaata ggagtcaggt agcttaagtg attcaattct ttaaggaacc gatttacttt
    16081 ttctgggtct tgttcgcagt aggtacggct cttttttaga ctatatccca tagcctttag
    16141 agcgtaatga atagttgttg gaggacagtt gaattcagca gctatttcag tcaaataagc
    16201 atcgggatga gtttcaatat agatctttaa tttatctcta tcaacttttt caattaatag
    16261 tggaagtttt cttgaagtta gtgtattgaa acgtttttat acagtgctaa aatttgaagt
    16321 gtagtgcaga tgtatttgta atagtattat agcaattctt tggagaaggt cgagacaaga
    16381 gaaaataggt atctttgaga tataagcatg atttactata aaattattga gttattcata
    16441 aaaatttctc tatcaaatat cataatgcgt cgtttaagga gatggttaca atgcaatata
    16501 gttgtggaaa aataaatatt aatatccctg atggatatgg agacattaag gatatagtgt
    16561 tttcggctca tattatagtt aggtataata atggacattg tggaggcata gatccgcata
    16621 taattggact ttgtaaaaag cagatcagaa ggatgtctct atatcctatt ttgataatcg
    16681 tatctagaga ttcaaaggtt attgatgatt ataaaaattt agatattgcc tatgttgatt
    16741 gtactcaatg ttcaaataat tttgaaactg ccttacacgt taaaaatatt ttaaaattat
    16801 taaaaatcca acttatacac tgtcatggct actcaactaa ttatttttta tatatgttaa
    16861 aaaaacttga caagaatgga tttggaaagg ttaagacagt gataacatgc catggatggg
    16921 ttgaatataa cttaaaaaag aaattcttga cttattttga tttttggaca tattctatgg
    16981 gagatgcttt tatttgtgta tctgaaacta tgaaaaaaag attggagagt ataataaaaa
    17041 ataagaagat agttgcaata aataacggaa ttaatgtatc aaatagcgat ttagatgtag
    17101 taggtgttca agactttaaa aaagaatttt gtattccaaa taacaaaaaa atcatttgtt
    17161 atgttggaag gttggatcca gaaaaaaggc cggatagatt ccttgaattt gcagaaaaat
    17221 tatttttagt cagagaagat gtgattttta ttatggctgg aaatggtagt atgtgggctg
    17281 ctttgaaaga aaaaatttgc tatttgaaat gtagagataa tttcaggtta cttggtgaaa
    17341 tctatccagt actatagttt accaaatatc ggatttattg tatattcctt ctgatacaga
    17401 aggaatacct atgtgtgttt tagagtcaat gtcacaagga actccggttt tagctagtaa
    17461 tgttggcggg ttaagtgaaa ttattgaaca tagggttgat ggatttttat ttgagaagga
    17521 agatgttgag ggagtgtgtg cttgtgctaa ttttttactc aatgattctg agtatttgaa
    17581 atatataggt gagaatagta aatcaaaaat aagaaaacat ttttctgtgc aaaaaatgtt
    17641 tgtagaaacc atgagagtat atgatgaatt attagagaag agtagtcatg gataggaata
    17701 tagatcaaga attagtaagt attataatac caacacataa taggtatg
//
LOCUS       DBJKQU010000044        17090 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.044, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000044 DBJKQU010000000
VERSION     DBJKQU010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17090
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.044"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(107..337)
                     /locus_tag="ACSUUC_001622"
     CDS             complement(107..337)
                     /locus_tag="ACSUUC_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054799.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(355..996)
                     /locus_tag="ACSUUC_001623"
     CDS             complement(355..996)
                     /locus_tag="ACSUUC_001623"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHQ8054800.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(1008..1742)
                     /locus_tag="ACSUUC_001624"
     CDS             complement(1008..1742)
                     /locus_tag="ACSUUC_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HHQ8054801.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1745..1942)
                     /locus_tag="ACSUUC_001625"
     CDS             complement(1745..1942)
                     /locus_tag="ACSUUC_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054802.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(1942..2148)
                     /locus_tag="ACSUUC_001626"
     CDS             complement(1942..2148)
                     /locus_tag="ACSUUC_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHQ8054803.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2158..2625)
                     /locus_tag="ACSUUC_001627"
     CDS             complement(2158..2625)
                     /locus_tag="ACSUUC_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054804.1"
                     /translation="MIDKVVRNLLLTFFFCKMTKIINFLTTIIVKKKKICYNEFKLRN
                     RKQKGVIMWVLGFILFMIFFYSNNSKKIKKLEKKIKRLERKEKGNAEMSRLLQEMIGK
                     EPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            complement(2768..4057)
                     /gene="hisS"
                     /locus_tag="ACSUUC_001628"
     CDS             complement(2768..4057)
                     /gene="hisS"
                     /locus_tag="ACSUUC_001628"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HHQ8054805.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4135..5382)
                     /locus_tag="ACSUUC_001629"
     CDS             complement(4135..5382)
                     /locus_tag="ACSUUC_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HHQ8054806.1"
                     /translation="MKLLFRNQAYRLLTLSRFFNAFGASIFNLVFIVYASTLPQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGSQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDRFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFFGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGFSLLAIFLTILNLKNDI"
     gene            complement(5572..6423)
                     /gene="rgg"
                     /locus_tag="ACSUUC_001630"
     CDS             complement(5572..6423)
                     /gene="rgg"
                     /locus_tag="ACSUUC_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HHQ8054807.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYKLNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6547..6888
                     /locus_tag="ACSUUC_001631"
     CDS             6547..6888
                     /locus_tag="ACSUUC_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HHQ8054808.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            6952..7161
                     /locus_tag="ACSUUC_001632"
     CDS             6952..7161
                     /locus_tag="ACSUUC_001632"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054809.1"
                     /translation="MKIKGQTRKLAAGCSKHCFEVMDRTDEVSSKHCFEVVDRTDEVS
                     PKHCFEVVDRTDEVSNHTYGKATLT"
     gene            complement(7187..8890)
                     /gene="ilvD"
                     /locus_tag="ACSUUC_001633"
     CDS             complement(7187..8890)
                     /gene="ilvD"
                     /locus_tag="ACSUUC_001633"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HHQ8054810.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(9123..10055)
                     /locus_tag="ACSUUC_001634"
     CDS             complement(9123..10055)
                     /locus_tag="ACSUUC_001634"
                     /EC_number="2.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HHQ8054811.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(10052..10909)
                     /locus_tag="ACSUUC_001635"
     CDS             complement(10052..10909)
                     /locus_tag="ACSUUC_001635"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HHQ8054812.1"
                     /translation="MILSKNREDELRKFAANIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPETFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(10913..12259)
                     /locus_tag="ACSUUC_001636"
     CDS             complement(10913..12259)
                     /locus_tag="ACSUUC_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HHQ8054813.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(12272..12556)
                     /locus_tag="ACSUUC_001637"
     CDS             complement(12272..12556)
                     /locus_tag="ACSUUC_001637"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHQ8054814.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(12560..14590)
                     /locus_tag="ACSUUC_001638"
     CDS             complement(12560..14590)
                     /locus_tag="ACSUUC_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHQ8054815.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPIIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKVSSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            14781..15788
                     /locus_tag="ACSUUC_001639"
     CDS             14781..15788
                     /locus_tag="ACSUUC_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HHQ8054816.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            15791..15991
                     /locus_tag="ACSUUC_001640"
     CDS             15791..15991
                     /locus_tag="ACSUUC_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HHQ8054817.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            16142..16324
                     /gene="rpmF"
                     /locus_tag="ACSUUC_001641"
     CDS             16142..16324
                     /gene="rpmF"
                     /locus_tag="ACSUUC_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HHQ8054818.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            16340..16489
                     /gene="rpmG"
                     /locus_tag="ACSUUC_001642"
     CDS             16340..16489
                     /gene="rpmG"
                     /locus_tag="ACSUUC_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HHQ8054819.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(16981..>17090)
                     /locus_tag="ACSUUC_001643"
     CDS             complement(16981..>17090)
                     /locus_tag="ACSUUC_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054820.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         5533 a         3602 c         2923 g         5032 t
ORIGIN      
        1 acaacctcaa aacagtgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt ataatacaaa aatccgatga acttcaccgg actcttttat tttgaatttt
      121 tgcctgcttt acgcttttca gcgatttcgg ctgcctttcg aggcaagaca atttccgtta
      181 tgtaagccgt cccaaaacgc agtacacctg caataggagc aaagacaact gctagatagt
      241 tatagaagaa atcgcctttg aaggcataag ctagcgctcc aatgatgaaa aatagaacga
      301 ctgcctgaat cactgctaat aaaattactc gtttcatgtg acctcctgac tctattatag
      361 catgagaatc atcaaaaagc cgactaaatt attcaaagcg tgaagagaaa tactgtagac
      421 cagacctttt ctgctaatgt aagccaaacc caaactaaaa ccaaggctaa aatagacaaa
      481 aaattgttgc acatcacctg gaaaatgaat caaggcaaat agaagactag ataccagaag
      541 aaaaatcagg gttcgtttac tattgtcctg cttaggaaag agatagcgtg ctaacatccc
      601 tctaaaaaca atctcttccg tcaaaggagc aaaaataacc acagcaaaga atgagaaaag
      661 tggttgagac aaggtcaagt ctgtcgctat ttgttgattt actgaaggat catctggcaa
      721 gaagaattga acgaccagag ataagaacca aaccaaggca ggaagccaaa taaatcggtt
      781 aaagccgctc ttctcaatat aaacaggagc tttctgatac catttgtaaa tgccgtacac
      841 atatactcca gccaagacca catagagtag agtaacagca tagggtgaag cgcctaaagc
      901 aagcgacgca gtcgcgagcc cctgaataaa gccatagata aagaaaaagg atagaagggc
      961 tagaagaaac cagccaaggt ttttaagtag tttcatagat aactccttta tttgaaataa
     1021 cgttttacca taggtaactg catcacattg atataaacat ggatggctcc tacaagcaag
     1081 aaagctagta actgaatctc tcctgtcaag aaagaaatga taataagaaa aatatataag
     1141 gctggtaaga catattggtg taattggaat aaaattcgaa aactctgttc caaattagcc
     1201 tgacgctccc cttcatcata agaatttata tagttcaaga catcctttgg tgtagcgaaa
     1261 aattccaaat caaactgacg aacaatcgca atggttttaa aaagagattt ttgagcgact
     1321 aagaatacca caaagagtaa gaaagaaagg aaaaatgttt gagggtttgt atgcaatata
     1381 atcacctcac ttaatgaaat aaaaatagcc aatggaatcg ctacacctgt aatattaaaa
     1441 gcaatggttc caaactcaag attccgatac atttgcacat aataggtttc attcagatcg
     1501 tcatccattt cctcttgata caaggaatga aattttctgc ttttctttaa gaaattgaaa
     1561 gtcaaaaaca tactaatgaa acctatcagt aaacaaatag ctgatatcca tggcatcaag
     1621 gcttttacat ctaaaataat ttcgtgggat tcgacacgtg ccttaaacat ccctacaaac
     1681 atgcccaaga acccccccaa gacaatagac atcaaaaata acaatctacg tttctttttc
     1741 atattcattc tcctttttca cttgctagat ttttggattt cttttcaatc cattcaatta
     1801 ctgggatgag agcaaagtag acccaaacaa attggtcgct ttgataggga ttaaaccagc
     1861 ttaggtccat cccaatcagt agaaatacgc tgactaataa agctatgacc actacataat
     1921 aaatcacttt atacttgttc atcactcgtc ctcctccaaa cgaaataccg attcgactgt
     1981 ttcgttgaaa atttgagata ttttcagggc aatgataatg gatggggtgt actcatcccg
     2041 ttctagtagg ctaatggtct gtctggaaac ccctgccagt ttggctaggt cggtttgatt
     2101 gagaccatcg cgagctcgaa gctcttttag acgatttttt agttgcatgt tacacaccta
     2161 ctctccgtca aattcaacgg tttggatatc ctcaatacgt tgcaacttga atttttcttt
     2221 tcccgtatta tctacacgtc gtagctttac ccattcctca tcaacatcca caacttccca
     2281 gttatctggc ccaatataca ctcccgttat aattggttcc tttccaatca tttcttgtaa
     2341 taatctcgac atttctgcgt ttcctttctc ttttcgctca agtcttttga ttttcttctc
     2401 tagtttcttg atttttttag aattattaga ataaaagaaa atcataaata gtataaatcc
     2461 tagtacccac attataactc ctttctgctt cctatttctt aacttgaatt cattgtaaca
     2521 tatctttttc tttttgacaa ttatagttgt caaaaagttt atgatttttg tcattttgca
     2581 aaagaaaaag gtcaggagta ggttcctgac cactttatct atcattaata ctcttctaaa
     2641 atctcttcaa accacgtcag cttcaccttg ccgtaggtat ggttactgac ttcgtcagtt
     2701 tcatctacaa cctcaaaaca gtgttttgag caacctgcgg ctagcttcct agtttgctct
     2761 ttgattttta ttgagtataa aatcctagtt tttcaaagat ttctgagaag ttttggctga
     2821 ttgtctcaag tgacacttgc acttcttctc gagtttggtt gttcttgacc gtcacttgtc
     2881 cgctttcgac ttcgctctct cctagggtga tgagggtctt agccacaaag acatcggctg
     2941 acttgaactg agcttttagt ttacggttga ggtaatcacg ctctgctttg aaaccttgtt
     3001 ggcgaagagc ctgtaccaat tccaaggcct tgatatttgc cccttcgccc aagactgcga
     3061 tatagacatc tagggcgttt tcgataggga gggtcacgcc ttgtttttca aggatgagaa
     3121 gcaggcgctc tacaccaagt ccaaaaccaa atccagcagt ttcagggcct ccaaagtaag
     3181 caaccaaacc atcgtagcga ccacccgcac agactgtcaa gtcattgccc tcaatctctg
     3241 tgataaactc gaaaatggtg tggttgtagt agtccagacc acgcaccata ttggtatcga
     3301 tgatgtaatc tactccaaga ttttccaaca tctgacgcac agcatcaaaa tgagtttggc
     3361 tttcttcatc aagaaagtcc aagatagacg gcgcattctc tactgccacc ttgtcttctt
     3421 tttccttaga gtccaagaca cgaagaggat tttcctccaa gcgacgttgg ctatccttag
     3481 acaaggtctc cttgagcggt gtcaaatagt caatcaaggc ttggcggtag gctgcacggc
     3541 tctcaggatt tccaagagtg ttgaggtgca atttgacacc ttgaataccg atttccttca
     3601 aaaaatgggc tgccataacg attgtttcca catcggtagc tggattgcta gagccaaaac
     3661 actcaacacc aatctggtgg aattggcgca agcgccctgc ctgtggacgc tcataacgga
     3721 acataggtcc catgtagtag aacttgcttg gcttttgcac ttctggggcg aagagtttat
     3781 tttccacata ggaacggaca acgggcgcag ttccttctgg acggagggta atatggcggt
     3841 cacccttgtc atagaaatcg tacatttcct tggttacgat atccgttgta tctccgacag
     3901 agcggctgat aacctcgtaa tgctcgaaaa taggcgtacg cacttctgcg tagttgtagc
     3961 gcttgaaaat ttcacgggca aagccctcaa cgtactgcca cttagcagac tcagcaggta
     4021 aaatatcctg cgttcctttt ggtttttgta atttcatagg gaatcctctt taaacttaat
     4081 agtcttattt taccataaat agagggatta aaacagtaag aaaaaaatta ggatttagat
     4141 atcatttttg agattaagaa ttgttaaaaa aatagctagc aaggaaaaac caacaaatag
     4201 catccaagtc aactgcatgt tccatacggc tactagtgaa aaacaagctg ttcccacagg
     4261 tatggataag gtaaacaata gaccgaaaaa attactagta cgagctagaa cctctggagc
     4321 tagatttttc atgagcatgg cactaatctt tggttgaact ttaccagaca catacagagt
     4381 aaagaagaga aatagcaaac caagcacgac ttgattgaat aaattagcca aaccaactag
     4441 actaagtcct acggtctccc acatcatcaa tctaggcaag gactgcttcc caaaataatc
     4501 attgcccgta aggctactga tgatgattgc tactaaaaca cagaattgat tgataaatag
     4561 tgcctctgta taagaaaaat tcaagagaga atggctcaaa aagaagatat tataaattcc
     4621 acccaaagcg ccacccaagg aattaataag caagacagca aagagcataa aaccaaagtt
     4681 tttctgtcca cttttaagaa aaacgagacg taaatttcgg taaattgtta ggaaccggtc
     4741 tttgatagaa agcttctcat tttttaagtt ttcaccatca gcagatgaca ttgacaggct
     4801 caatttgctt tttcctaaaa agaggatagt ggctgatact aggaaaaagc aggcattgat
     4861 tcccgcaacg agagaaaaat tattgaccga tagagctaag agccagactc cgaaagcttg
     4921 actaccaata gctgaaatat aggtgatgaa ctgtgaaaaa gaataagcct ccatcaaatc
     4981 atcttcagct actttttcct taataagagg catacgcagg ccacctgcaa aatcactgat
     5041 gacatcacta atgacattga tcaaacacag gctagaaaag gcaaagagac tagcttgctg
     5101 aacaactagg gctgctagaa aaaatagaac cgcctgaaac aaaccgctat agaccatcca
     5161 tttgaccttg tccctcgtgt aatctgcccg aatccctgca aaaactgtaa agagggtcgg
     5221 aagaatcatg acaatattcg ccatagcaac agcaaaagat gcttgtggca aggtcgatgc
     5281 atagacgata aagaccaggt tgaaaatcga agcaccaaaa gcattgaaga agcgtgacaa
     5341 agtcaatagg cgataagctt gatttctaaa caatagtttc atagataatc tccctccttg
     5401 ttctaagttc tacatcaaga atagctttag tatagcactt atgaatttgc gaaacaattc
     5461 ttttgaatat atgcaacaaa taaaatgagc aaaaaacgat agaacttttg taatgacctg
     5521 agaaagggca acagttctat cgcttcaaat tttttcttag tttgcagata ttcaacattc
     5581 ggtcgtattt ctatagtatt cggcagattt attacagcca agcatctcaa aaatacggac
     5641 agcatcctcc atctttttct ggccttcctt gactctacct tgcttgctat caaggagacc
     5701 ttctgcccac agataaacaa ttcggaaata ggtctcattt tccttgtaga aatgctcttc
     5761 gataacacgt ttaaaataat aggcattggt aaattcttca cactcaatac tagctaaaaa
     5821 gccattcaat agtatagtat gaaaaaggtt tcgattgcca gacatttcca ttagaaaatc
     5881 agatttacgt accatttctc gtacatatct agtaaaaaga gaaacagata aaaatggaga
     5941 actgactgaa aataaattga gtttatagat tccccagatc tcggtagaaa acaaataatc
     6001 atgaaggact tttccttcct ctgctgttaa ctctaccctt tcatccatgc tcttcatata
     6061 agacttgatc ataatggcat ttagaatatg tttctgtttg ttgtgagaat gggcatgctt
     6121 ttgatactcc ctgcgatata agtcctcaag aggtgctata ttctttggtt ccaagacatc
     6181 tgtaatttct tttctcaact cagaatctgt atcatactgg aaacctctcg ccagaaagag
     6241 gatctcctcc acactggcag atatattttc cagagcaaat agaaactttt ccaccgaaag
     6301 ctcactctga cctgtttcaa aacgggacaa catagacggc gaaaattgtc ctccggttgc
     6361 ttgtctcagt gagatatttc ttgattctcg taattgtcta aagacttttc caatctgctc
     6421 catagacttc cccttgatcc cgtattttct tcattttatc atatttttca gaaaattcat
     6481 caaaaacttg ccaaattgtc agaatcatga gaaaatagag gatatttatc acgtggaggg
     6541 actgctatga gagacgatat caaaatcaat gaccgtgctt tggccttgca agaccaaatt
     6601 atcgaaaaac tagagaaagt ttttgataca gatgtggaat tggatgttta caatctaggt
     6661 ctgatttatg aaatcaatct ggatgaaacg gggctctgca agattgtcat gaccttcacc
     6721 gatactgcct gtgattgcgc cgaaagcctg cctattgaaa tcgtggcagg tctgaaacaa
     6781 atcgagggta tcaaagatat caaggttgaa gttacctggt cgcctgcttg gaaaatcaca
     6841 cgaatcagtc gctatggccg tattgccctt ggactaccac ctcgttaagc aggccaatca
     6901 cttttaaaga tgaaaaaagc aagccgaaaa tggcttgctt tttgatactc aatgaaaatc
     6961 aaagggcaaa ctagaaaact agccgcaggt tgctcaaaac actgttttga agttatggat
     7021 agaactgacg aagtcagctc aaaacactgt tttgaggttg tggatagaac tgacgaagtc
     7081 agcccaaaac actgttttga ggttgtggat agaactgacg aagtcagtaa ccatacctac
     7141 ggcaaggcga cgttgacgtg atttgaagag attttcgagt atgagtttat tttttacctg
     7201 acttgtccat attccagaag tctgtcacgg ctccgcgtga agcagatgat acgatgtggg
     7261 catatttacc gaggacacca cggctgtaaa gtggtggcaa ggttgtttct gccttgcgtt
     7321 tttcaagttc ttcttcggat acggccatgg aaatttcttt ggtatcttgg tcaaccgtaa
     7381 cgatatcgcc ggtacggaga taggcaattg gtccaccatc ctgagcttca ggagcgatat
     7441 gtccaacaac cagaccataa gtaccaccag agaaacgtcc gtccgtcaag agggccacct
     7501 tatctccctg acctttacca acaatcattg aagaaagtga cagcatctca ggcataccag
     7561 gaccaccttt aggtccaaca aaacgaacaa cgactacatc gccatcaacg atttcatctg
     7621 tcagaacggc ctgaatcgca tcttcttctg agtcaaagac cttagctggc ccaacgtgac
     7681 gacgcacttt aacacctgat accttggcaa ctgcaccgtc aggagcaagg ttcccgttca
     7741 agatgataag cggaccatcc gcacgttttg gattttcaag tggcatgata actttttggc
     7801 ctggagtcaa gtctgcaaag tcagccaagt tttcagctac agtcttacca gtacatgtga
     7861 tgcgatctcc gtgaaggaaa ccatttgcca acaagtactt cataaccgca gggacaccac
     7921 cgacttcgta gaggtcttgg aagacatact gaccagatgg tttcaagtcg gccaagtgag
     7981 gcacacgttc ttgaatcgta ttgaagtcct caagtgacaa gtcaacattt gcggcatggg
     8041 caatggcgag caagtgaaga gtggcgtttg tagaaccacc gagagccatc gttacagtaa
     8101 tagcatcttc aaaggcttca cgagtcaaga tatctgatgg tttgagacca agttccaaca
     8161 tcttaacaac agcacgtcct gctgcttcga tatcttcttt cttatcagct gattcagctg
     8221 ggtgagagga tgaccctggc aaactcatcc ctagaacttc gatagcagtt gccatggtat
     8281 tagcagtata cataccacca cagccaccag ggccagggca ggcattacat tcaagacgtt
     8341 tcacgtcctc agctgtcatg tcaccgtggt tccattttcc gataccttca aagacagaaa
     8401 ccaagtcgat atctttacca tcaagatttc ccggtgcaat agttccacca taggcgaaaa
     8461 tagctgggat atccatatta gcaatagcaa tcatagatcc aggcatgttc ttgtcacagc
     8521 caccgatagc gacaaaggca tccacgttgt gaccactcat agccgcctcg atggagtccg
     8581 cgatgatgtc acgagatgtt agagagaaac gcataccagg cgttcccata gcgatcccgt
     8641 ctgctacggt aatggttcca aactgtacag gccaagcgcc tgcagatttg acaccttctt
     8701 tagccagttt cccgaaatca tgcaagtgaa tgttacatgg tgtattttcc gcccaagtcg
     8761 aaatcactcc cacaatcggt gtttcaaagt ccttatctgt cataccagtc gcacgaagca
     8821 tagcacggtt aggtgattta accatgctgt cataaatgct actgcggtga cgtttatcta
     8881 attcagtcat cttatccctc ccatttcagt ttttactatt atagcacaat tttcgcatga
     8941 agaacagaat aaaaatcttg aattttcaga aaattctata cacatgtgaa atatttaaaa
     9001 ttaaaaacaa caaagcggat tagtgcactt tctgatgacc agaatatgct ttttaatccg
     9061 ctttctttaa ataacgtact gtaattttta cagaaattct ttcagataag tgtatttaac
     9121 atctatcttg cattataaat ttctagaacc ttctctttta tattcgattc actcaaacca
     9181 tactcattaa gaagataatc cattttccct acttgaccga atctttcttg aacacccatc
     9241 cgatgaattt ttgtcattcc atcatcagag aataattcac ataaagaact gccaattcca
     9301 cctatctgat tgtggttttc tacagtaaat atagtttttc cacttaacat tgtttttatc
     9361 tgttctggta tcggtttgat tctaaataaa tctatcacac ttactgaata acctaattta
     9421 gacagttcat ctgcaactcg aatacttgga gcaaccatta taccagaagc aacgattaca
     9481 agatcttcac catgccttaa ctcaatgtag cctttagaaa aatcttctcc accttgatac
     9541 acaggaactg gagcttttct aattgttcga atatatttta gtccttttaa gtctaatgtc
     9601 tggttcaata tttcacgaaa ttggatatca tcagttgctt caaaaatgat cgatttagga
     9661 attaaacgta acaatccaat ttcttcaaat ggcatatgtg ttccaccatt catctctgcc
     9721 gttactcctg catctgatcc aatcacagtg gcatccaatt gtgcgtatcc aagagaaata
     9781 aataattgat caaatactct tcgtgaagca aaaggaccaa atgtatgaag ataaggtcta
     9841 aacccctgaa tagacaagcc tgctgcaagg ccgaccattt ctgcttccat aatcccaaca
     9901 ttcacataac ggtctccaaa atccttttca agattattag tagccatcga acttgacaaa
     9961 tcggcttcta agactactat atcagaataa ctttgattag cctctaaaag gaagtctcta
    10021 tatacatgcc gtaattcttt cgtgcttctc atcattctgt ttcctccaat tcctgactta
    10081 atctttctac aactgaagtt aacatttgtc tctcctctac agtagggcga agatgatggt
    10141 tggatttcat ttcttccagc tcttgaaccc cttgaccttt aatagtatct aatacaatgc
    10201 acttaggtga tgaattattt gactgtttta attggacaat cccttcataa atttctctaa
    10261 tatctgaacc cttgacccta atggattcaa atccaaatgc tgaaaatttt tctacgaaat
    10321 cacctggatt acaaatatcc tttgtaaaac catctaattg ttttttgtta tcatcaacaa
    10381 atacaattaa gttggataac tgttgatgag aagcaaactg tatagcctcc caacattgtc
    10441 cctcatttaa ctcaccatct ccaacaatag cataagtata aaagggactc tttcttattc
    10501 tctgaccata tgcaagtcca gttgcaacac taattccttg tcctaaagag cccgttgtca
    10561 tatctatgcc tggcgttaga tttctatcag gatgagacgg taatttggtt ccatttgtat
    10621 ttaaagaata taagaattct ttgtcaaaga aaccattcaa atagagtgta ctgtatagag
    10681 ctggtcctcc atgacctttt gataatatga aataatctct atctcgtgct gcaaatgttt
    10741 ctggagtcat tggcattatt tcaccataaa gcactgctaa aacttctacg atagacagac
    10801 ttcctccgta atgtccgaat ccaagatgat tcaatgttct aagagtattt aatcggatgt
    10861 tagccgcaaa ttttcttaac tcatcttctc tatttttact taaaatcatc ccttattcct
    10921 cctttgcaga tggcttttta ataaaggata ctccaaacat aactgctaaa ataagaacaa
    10981 gaccaatcac aatgcctgct tgtgagccaa attgatttaa cattcctaaa ataattcctg
    11041 atagaccaaa atctgcatct gagaaagttg atccttggaa accgagtcct cccaaaactg
    11101 gcattaaaaa gactgggaga aaactgatta aaataccttg taaaaatgct ccaatagtgg
    11161 ctccacgaac accaccagat gcattcccaa taacacctgc agtcgctcca cagaagaaat
    11221 gaggcacaac gcctggtaag ataacaaccg ttcctgaagc aatcataatt gccatactta
    11281 ctaaaccacc aataaaacta gagataaatc caattagaac tgcattaggt gcataagtat
    11341 aaacaatcgg acaatccaaa gcaggttttg aattaggtac aagacgctct gaaatacctt
    11401 taaaggctgg aacaatttcg cccaaaataa ggcgaacacc tgctaaaata acaaataccc
    11461 ctgctgcaaa ttgacctgct aattgtaaag cataaactag accacttgta ccactactga
    11521 tttctttttc tatatattct gaccctgcaa agatagctac aataatgtaa ataactgcca
    11581 tagataaagt gatactaaca gtactatcac gtaaaaaagc taaactcttt ggaaatttaa
    11641 tgtcctctgt tgattttgat ttgtcaccga taaggctacc agtaaaacca ctcaaccaat
    11701 atcccaaaga actgaaatga cctaaagcca ccttgtcatt tccagttaat tgaaccatat
    11761 atttttgcac aaatgctggg gaaatactca taataatacc gagtgctaat cctcctagta
    11821 agatgagagg caagctagta aagccagcaa ctgataaaat gaccgcaatc atacatgcca
    11881 tatatagagt gtggtgccct gttaaaaaaa tatatttaaa tcgagtaaaa cgagcgatta
    11941 agatattgaa caccattcct gcaaacataa tcattgcagt agctgagcca tatgttgtta
    12001 aagctacagc tacaattgct tcattattcg gcacaacgcc agataaatga aaagcatgct
    12061 caaacatggt accaaatgga tttaaagaat tttgtacaat tcctgcacca ccagatacaa
    12121 ctaagaaacc aacaaaggtc ttaattccac ctttaataat atcaggtaat ttcttcttct
    12181 gaagaactaa tcctaaaatt gcaattaaag ctactaaaat agctggtgta ctaacaatat
    12241 ccaatatgaa cttcatcatg acgctagcct cctatataag tcctttttct tcacaaagtt
    12301 tagtaattaa ttctcgtagt tcatccatat caataatact atttaagata cgaacatctc
    12361 caagatgact agctgaatca gctagatcac gaccaacaat ccaaatatca gctgcatttg
    12421 gatctgctcc acctaaatca taatgttcaa cttctacatc cgaaacattc aaatcactca
    12481 atacagattc aatattcatc tgtaccataa aacttgaacc taatcctgaa ccacaagctg
    12541 taccaatttt taacattatc taatcctcct gtttaattat cattttaata tcattatagt
    12601 tttttgatga tattaaagtt tgaacatgat ttttatctct taaaattgtt gttaaatgtg
    12661 acaaagcctt taaatgactc tcattatcaa tggctgcaat acaaatcaac aatcttacct
    12721 cttgttctgg attatccaat aaataaatcg gttcttccaa aactaacatt gacattccta
    12781 tttcattcac accttcatct ggccgagcgt gaggaattgc tactcccttc cctaaattaa
    12841 taaaaggtcc aaactcttct actttttgaa tcattgcctc agggtagttc tcagttatct
    12901 tatcttgatc caaaagcggt ttagctgcta aacgaatcgc ctccttccat cctaattttt
    12961 gcgaactaac ctgataggtt tctttggtaa taagttgttc tagcactggt acaatttcct
    13021 ttctatcatt tttttgataa agataattct ttaacgccaa tcttaattcc aattcttgtg
    13081 taataattcc atatcttttg acaatattca ggatttgttc aatctcaaaa tctccatact
    13141 ctaaattcgg aaaatctttt aacactagtt ctactagttg tattgcttgc tcttcagtca
    13201 tcataaccga aactagataa tttggctttt ctgtctccac ctttatggta gaaaaaacca
    13261 tatcatagtc actactaact ttcacctgta aatcatcaat ctttgaggtt cctataaact
    13321 caatttgagg aaataatgct aatagattct cttttaacat caatgaagaa ctaacaccat
    13381 taggacaaat gattgctgct ttataccatt tttgaggcaa agtatctgct ttctttaaat
    13441 aacctccgaa atggataaca aaatatgctg tttcactatc aggtatggga ttgtcaatag
    13501 cgtccatcaa gggcatcaaa gaatctttga ctaattcaaa taaatcagga taatgttctt
    13561 taacatgcaa tacatattca tttgaactag gtaggccgaa ctttaatcta tagtaagccg
    13621 gtataaggtg gcggcgaaga ttttctctca atccttccct ttgtttaaaa tgtaacaaag
    13681 aaatatcttc cattctactt ataatagcct ctgttaattg attaaagtaa accggagcaa
    13741 catctacttc accttcaaag caacttgata ataaaacggt gatatagcga taatcatcct
    13801 cagaaaacac cgtatctata attcccaaat caaccactgt atccaataaa atagtcgtta
    13861 tatcttgaat aataggagat actaatgtct ctgaaagaca cactctttca acatcccttt
    13921 gatacctaca cagaatgaat actaaaccga aaaggtaaac ttttaattga ttaacaatag
    13981 gtactagctg tagcttctca taataatctt taactacctg atcaatcaaa tcataagtta
    14041 atgaataccc ccaactggat aaaacataat ccaaacccca aatccctatg gaggattcca
    14101 gcaactcact aaccatttga aaagctaagc ggtgcttatt ccactctgaa ccgtgtaaag
    14161 tataaccttt tgctctactg taccctagct ccaaatcatt atctaacata atctttctta
    14221 atgattgaat atcagataag gttgtattct tacttacttt caaaaagtct tggtaatgac
    14281 tattcgatat aaaatctaat cggcaaaaag tgtaaagata gattaaagct aagcgagtcg
    14341 actttggtaa aaccaattca tccgacttaa taatatctgt caaagactgc ttcgtacgat
    14401 ttgataaact atagcgacct tgctttttat ccagcactat ccctttatta gctagataag
    14461 gcactaaata atctattcct tctttgactt cctttatagg taagctcacc ttaacagata
    14521 attcatataa tgatagctca caatgatcca tcaaagtcat caaaataact agtgctctat
    14581 aatcaaacat ctctcttcct ttctaactac aattatagtg taaaaattat aagaataaaa
    14641 gagtatttga gcacaatata atctcacctt ttaaaagaaa ttattgggct gaaacttttt
    14701 agtgattatt ttcaactttc tattgacttt taaaaacaaa gtgatatcat ttagatatca
    14761 aataatggga ggtcattctt atgactgaaa aactaatcaa ttcaaaacca aatggtgtat
    14821 tcgcattgat tctcattgag ttgacaatcg tacttggtat ctttatattt ataatggggg
    14881 ttggttcgga aaacattttt ggaattatta tcggaccttt actaatcgta attgcaggtc
    14941 tagctcatgc tggtttaaaa gttgtcaaac ctcaggaagc tctggttctg acactctttg
    15001 gtaattatac aggtaccatc aaagaacctg gtttttactt tgtcaatccc ttcagcgtag
    15061 cagtcaaccc tgcaaaccac actcgacttg gacaaagtgg tgatgttagc acaaaatctc
    15121 cttttttagg agctaaatca tcaaatgaca atgatgtaaa tcttgaaatt ggcaagaaac
    15181 acatttccct caaagtcatg accttgagca attctcgtca aaaaatcaat gattgcttag
    15241 gaaaccctgt agaaatcggt atcgcggtaa cttggagagt tgtcgatacc gctaaggcag
    15301 tcttcaacgt tgataactac aaagaatatc tttcattgca atgtgatagc gccctccgta
    15361 atattgtccg catctatcct tacgatgtgt ctcctaatgt ggatactacg ggtgacgggc
    15421 aagcagatga aggtagtctc cgtggctcta gcgaaattgt tgctaaccgt attcgtgaag
    15481 aaatccaaag tcgtgttgag gatgctggct tggaaatcct tgaagcacgt atcacttacc
    15541 tagcttatgc tccagaaatt gctgccgtta tgcttcaacg ccaacaagca tctgccatta
    15601 ttgatgcacg gaagatgatt gtagatggtg ctgtaggaat ggttgaaatg gcactagaac
    15661 ggctcaatga aggggaattg gtagaacttg acgaagaacg aaaagctgcc atggtttcaa
    15721 atctccttgt cgttctttgt ggcaatcatg atgcacaacc aattgtcaac acaggaagtc
    15781 tttactaaag atggctgaag ctaaaaaaaa gcagatcccc cttcgactct caacaaagtt
    15841 atacgctgca ctcgcatcat gggcagaaga cgactttcgt tcagtcaatg ggcaaatcga
    15901 atatctcctc acagagtgtg tcaagcaacg gaagaaagac ggaaaatacg tatcagaaac
    15961 cattgacgaa ccatttgaga ttgatattta acaccttctc ctgtctgccg tgtcggatag
    16021 gagaattttt tcatcttttt tgtcaagtaa ctttacttta caaaaaaaat gtgttatcct
    16081 agtatggttg atgaaaatca gtagattgaa tcgaatataa atacctaaag gagaaatcaa
    16141 aatggcagta cctgcacgtc gcacttcaaa agcgaagaaa aacaaacgtc gtacacacta
    16201 caaagtaaca gctccatctg taaactttga cgaaactact ggagattact cacgttctca
    16261 ccgtgtatca cttaaaggat actacaaagg acgtaaaatc actaaagctg catcagctga
    16321 ataatagaag ggagatacca tgcgcgtaaa tattacactt gaacacaaag aatctggtga
    16381 acgcttgtac cttacttcta aaaacaaacg taacactcca gaccgccttc aattgaagaa
    16441 atactcacca aaacttcgca aacacgttgt gtttacagaa gttaagtaag cattcaatac
    16501 gaatcaatac agaagaaaaa cgcttgatca gcggtttttc tttttgttaa tttcactata
    16561 ttgcaaggga aatcattcga atgactacat ttttcactac cttttttgaa ataagaatac
    16621 ggattcggac gattaaaagt aagagaaact caaatgtaag ttggggttcc ttttttgtat
    16681 atttttcaaa taacgcctct acactatttg tagcaaattc accaactaca gttgtatctt
    16741 agttaaaata agttagaata tgtaagtgag taccagatat accaagacat cgtcaccatc
    16801 taaggtatat tcaaaataca aaagttgacc aactagattt ctgaatatcc ttatatatcc
    16861 attcttaaaa ttggtttaaa tagcgtagtc ttttaaacta gttttgagaa tccaaaaaat
    16921 cttcctacat atgtaagaag attttttagt tcagaatgat tagatttagc taatggatac
    16981 ctatcctacc cactcaccgt tagcattgac tcgatagcca tcgggtgtag tcgtgtttac
    17041 taataaatct cctgaattat aggtatagta ccatttacca gaaactgtaa
//
LOCUS       DBJKQU010000045        16652 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.045, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000045 DBJKQU010000000
VERSION     DBJKQU010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.045"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            223..318
                     /locus_tag="ACSUUC_001644"
                     /pseudo
     CDS             223..318
                     /locus_tag="ACSUUC_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(571..1191)
                     /locus_tag="ACSUUC_001645"
     CDS             complement(571..1191)
                     /locus_tag="ACSUUC_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HHQ8054821.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTPNTWNDTSYQS"
     gene            complement(1191..1673)
                     /locus_tag="ACSUUC_001646"
     CDS             complement(1191..1673)
                     /locus_tag="ACSUUC_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HHQ8054822.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1673..2515)
                     /locus_tag="ACSUUC_001647"
     CDS             complement(1673..2515)
                     /locus_tag="ACSUUC_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HHQ8054823.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSH
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2610..3410)
                     /locus_tag="ACSUUC_001648"
     CDS             complement(2610..3410)
                     /locus_tag="ACSUUC_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003796 - lysozyme activity [Evidence
                     IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA];
                     GO_process: GO:0016998 - cell wall macromolecule catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH25 family lysozyme"
                     /protein_id="HHQ8054824.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3554..4933
                     /gene="glmU"
                     /locus_tag="ACSUUC_001649"
     CDS             3554..4933
                     /gene="glmU"
                     /locus_tag="ACSUUC_001649"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HHQ8054825.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGNNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4943..5488
                     /locus_tag="ACSUUC_001650"
     CDS             4943..5488
                     /locus_tag="ACSUUC_001650"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHQ8054826.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5500..5814
                     /gene="macP"
                     /locus_tag="ACSUUC_001651"
     CDS             5500..5814
                     /gene="macP"
                     /locus_tag="ACSUUC_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HHQ8054827.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5831..6523
                     /locus_tag="ACSUUC_001652"
     CDS             5831..6523
                     /locus_tag="ACSUUC_001652"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HHQ8054828.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6600..7091
                     /gene="rocS"
                     /locus_tag="ACSUUC_001653"
     CDS             6600..7091
                     /gene="rocS"
                     /locus_tag="ACSUUC_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HHQ8054829.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7189..7779
                     /locus_tag="ACSUUC_001654"
     CDS             7189..7779
                     /locus_tag="ACSUUC_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HHQ8054830.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7788..9551
                     /locus_tag="ACSUUC_001655"
     CDS             7788..9551
                     /locus_tag="ACSUUC_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HHQ8054831.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINFLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFEFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMDRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            9765..10407
                     /locus_tag="ACSUUC_001656"
                     /pseudo
     CDS             9765..10407
                     /locus_tag="ACSUUC_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            10574..10774
                     /locus_tag="ACSUUC_001657"
     CDS             10574..10774
                     /locus_tag="ACSUUC_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054832.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATQAVLLDAQKAPEDSALTE"
     gene            10799..11215
                     /locus_tag="ACSUUC_001658"
     CDS             10799..11215
                     /locus_tag="ACSUUC_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EGFR-like transmembrane domain-containing
                     protein"
                     /protein_id="HHQ8054833.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            11446..12153
                     /gene="ccdA2"
                     /locus_tag="ACSUUC_001659"
     CDS             11446..12153
                     /gene="ccdA2"
                     /locus_tag="ACSUUC_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HHQ8054834.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLTLASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            12164..12721
                     /gene="sdbB"
                     /locus_tag="ACSUUC_001660"
     CDS             12164..12721
                     /gene="sdbB"
                     /locus_tag="ACSUUC_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HHQ8054835.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            13095..14486
                     /locus_tag="ACSUUC_001661"
     CDS             13095..14486
                     /locus_tag="ACSUUC_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HHQ8054836.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            14629..15546
                     /gene="adcAII"
                     /locus_tag="ACSUUC_001662"
     CDS             14629..15546
                     /gene="adcAII"
                     /locus_tag="ACSUUC_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HHQ8054837.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            15554..>16652
                     /gene="phtB"
                     /locus_tag="ACSUUC_001663"
     CDS             15554..>16652
                     /gene="phtB"
                     /locus_tag="ACSUUC_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HHQ8054838.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEERIA
                     RIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPS"
BASE COUNT         5157 a         2954 c         3512 g         5029 t
ORIGIN      
        1 ttaacacctg ataatatgcg ttttttgatt ttaaagactt tttgaccagt ctcatttttt
       61 taacttgata ctcagtgcaa agcaaagatt aaactaggaa gctagctgta ggctgctcaa
      121 agaacagctt tgaggttgta gataaaactt gtgaggtcac caacatatat aatgtgaagc
      181 tgacgtggtt tgaatagatt ttagaagagt atgagtctgg aagttttaat ggataatgca
      241 agattccata gaatgggtaa gctagagttc ttatgtgaag agtttgggca taaactttta
      301 ccttttcctc cctactcatc ttagtataga aaagtgaatc tgaaatagta cataactgct
      361 tctaaaacat tcttataaat tgatttaaat tctcaaatca tattattcag ttcttatttc
      421 attttgttct acaatcctgt tgagaagaca cgtgttcata tcaaaaaggt attggcaagt
      481 tgcaatacct ttttacgagg ctctgttgtc ttatttttgt ttcaactgac tatatctcct
      541 atggttctag ttcagaaggc taggctataa ttatgattga taagaagtat cattccaagt
      601 attgggagtg aatgtttcaa aatcatgggt ttctataatg gtcaggctgg catttgctag
      661 accgccatct ttacgaagaa gtggttcttt atagcctagg agagtacgaa gactggcagt
      721 aagattggcg ccgtgtccga caattagaat acgttcagct ggactatctt ttaatgattt
      781 gataaattgg atggtccgtt gagttgtact atagagggat tcggctccga acattcgagt
      841 gtcaaattga gcaagatttg aacgaaaagc ctggatttgt tgcgggtaaa tagcttccaa
      901 ggttgcaatt ttcaaacctt ctaacttccc aagttgccat tcacggagat taggaacgat
      961 ttctaaagaa cagggggtat agagttgact ttggataatc tcagcagatt tgaccgctcg
     1021 aggtaaatca cttgaataaa tctgatcaaa aggaatttcc ttgagatact gaccaagtcg
     1081 ttttagggtt tcaatggatt caggaagaag aggagaatca ccactagcac cttgaaaacg
     1141 accttcttgg ttccagaggg tacgaccgtg gcggacaaag tagagtttca ttacttgatg
     1201 tcctccaaaa tatctacaaa gtctgccttt acaaagctag ccaagtcttg tggcgcgacg
     1261 ataatgctgt gtccgacttc gcctgcagag acaatcattt gatccaaatc tagagcaatt
     1321 ttatcgataa aaatgggata attgtgtttc tgacgaattc cgacaggatt attggctcca
     1381 tgaatgtaac cagttgtttt ttctaagtcc ttttgtggaa tcatgctcac ttttttattg
     1441 ccagaaattt tagctagttt cttttcagac aagtgctgag tgatagggac aattccgata
     1501 atcggtccgg tcttgtctcc caaaagcgcc aaggttttga aaatctgatc tcgttcataa
     1561 ccttgaggaa gctctccttc tagggcattg atttgaatcc cctgatgagg gatagctgct
     1621 ttagatagga tttgttccac caatgttttt ttgattttaa ctttttttgc cattatttat
     1681 atttatcctc caattgactc atccaaatac caagccagat tcccagcgca aagaagaagg
     1741 cgatgatgac ataaccgaca agtgaaagtc ctgtgtattg gatactttca gcgtttcctg
     1801 catttggaat taagatcaaa agggtacttg ataggacgat accgatgatg aaatgataga
     1861 cgtgtgagtg gtagttgttt aaggcataat ccatcaattt tgaaaaaacg atgagagttg
     1921 cacctgcacc aattccaatc ggaaagaagg ttcccaagag atcaaaagtt ttaaaaccag
     1981 tcaacatagg agcatagagt cccaaaatca aaagtaagtt cgatgggctg aggccaggaa
     2041 ccaagacgcc aagggccaat agtgcgcctg ctaggacgaa gttaagaaag ctggcgctta
     2101 aggttccaac gacaaaattt aaggcataga gtcctaatcc agaaatgata aaggttgtcc
     2161 ataaccaagc taaatcaatc ttgtctcggt cagattctcg agttgattct ttgaggaggc
     2221 taggaactgt accgataata gctcccgcaa agctccataa tacaaaaacc tgataatttt
     2281 caagcaggta ttcaatcggg taggaaaata agccgattcc cagaagcata ccgatggcaa
     2341 ctggaataaa gtacaaaaca ttttctttaa agtctttaaa gggatgggcc agaaagccaa
     2401 tcattcgttc atagattcct aagattgctg ctagaacccc tccggaaatt cccggtagga
     2461 taaatccaag agcaattaca atccctttaa taacgcgtgc taaccatgag agcatatatt
     2521 tcctccaact atttctattt caaaaaatcc ttactatatt gtatcacaat cagacacaaa
     2581 aagaaaaagc aaatgataaa caaatgcttt taaggtttta aaaaaagttt tcgaaaggtt
     2641 tcttctttat tttttaaggg agagataacg ttgatatcta aatcgtggtc aaagccagca
     2701 atttttcctt tagatgtgta ttggtgaata tcataatcta aatcagtttt aggactgctc
     2761 tccaaaaatc ctgagtctga gccgtaggac ggaatccaaa cagaggtaaa cttgcctgta
     2821 tcaatactgt gttcttccat gaagtagaca ccaacgtaga tgccgatgtt tttagcacct
     2881 agtgatgcta gttttgctcg aaagttttcg acaccttcgt tcatattaga catggttttg
     2941 tcttccacgt caagccaata gtaactaggg ctgtaaggag aggcagcatt gtagaaaact
     3001 tcggcagcct tttccatttc ttggacactt tttccagcta cataagcgta gacagcaact
     3061 gggacattcc gcttttgaag ttcagtgata tgactcttat aggccttgtc tattccattg
     3121 ataaatgaag catcattttc ttttgttgtt tgagcaccac tgtgaacacg aacaatagca
     3181 cctgaaatat tttgtgagag ggcatcgtag ttgatttcct caggacgctg ccagccagag
     3241 aggtcaataa tcggtttgtc taagtgtttc aaagcctgtg cttcaatctg tgctatattg
     3301 gattttgttt taaacgattg gctgtcatta agtgggcgat tgatgattaa aatgaacatc
     3361 ataatcccaa aaaaactaaa taaaataagt ggatgaattt gttttctcat atcttataat
     3421 tctaccctaa aaatcaaaaa aaatcaaaaa aatgggttaa ggaagagact ttagagcatt
     3481 ttttcattca agagtgcgga atgatttgaa atatggtata ataaaaggga atttctacag
     3541 aaaagagaag attatgtcaa attttgccat tattttagca gcgggtaaag ggactcgcat
     3601 gaaatctgat ttgccaaaag ttttgcacaa ggttgcgggt atttctatgt tggaacatgt
     3661 tttccgtagt gtgggagcta tccaacctga aaagacagta acagttgtag gacacaaggc
     3721 agaattggtt gaggaggtct tggctgaaca gacagaattt gtgactcaat ctgaacagtt
     3781 gggaactggt catgcagtta tgatgacaga gcctatctta gaaggtttgt caggacacac
     3841 cttggtcatt gcaggagata ctcctttaat cactggtgaa agcttgaaaa acttgattga
     3901 tttccatatc aatcataaaa atgtggccac tatcttgact gctgaaacgg ataatccttt
     3961 tggctatgga cgaattgttc gtaatgacaa tgctgaggtt cttcgtattg ttgagcagaa
     4021 ggatgctaca gattttgaaa agcaaatcaa ggaaatcaac actggaacat acgtctttga
     4081 caacgagcgt ttgtttgagg ctttgaaaaa tatcaatacc aataacgctc aaggcgaata
     4141 ctatattaca gacgtcattg gtattttccg tgaaactggt gaaaaagttg gcgcttatac
     4201 tttgaaagat tttgatgaaa gtcttggggt aaatgaccgt gtggcgcttg cgacagctga
     4261 gtcagttatg cgtcgtcgca tcaatcataa acacatggtc aacggtgtta gctttgtcaa
     4321 tccagaagca acttatatcg atattgatgt tgagattgct ccggaagttc aaatcgaagc
     4381 caatgttatc ttgaaagggc aaacgaaaat tggtgctgag actgttttga caaacggtac
     4441 ttatgtagtg gacagcacta tcggagcagg agcggtcatt accaattcta tgattgagga
     4501 aagtagtgtt gcagacggtg tgacagtcgg tccttatgct cacattcgtc caaattcaag
     4561 tctgggtgcc caagttcata ttggtaactt tgttgaggtg aaaggatctt caatcggtga
     4621 gaataccaag gctggtcatt tgacttatat cggaaactgt gaagtgggaa gcaacgttaa
     4681 tttcggtgct ggaactatta cagtcaacta tgacggcaaa aacaaataca agacagtcat
     4741 tggaaacaat gtctttgttg gttcaaattc aaccattatt gcaccagtag aacttggtga
     4801 caattccctc gttggtgctg gttcaactat tactaaagac gtgccagcag atgctattgc
     4861 tattggtcgc ggtcgtcaga tcaataaaga cgaatatgca acacgtcttc ctcatcatcc
     4921 taagaaccag taggagccta tcatggagtt tgaagaaaaa acgcttagca gaaaagaaat
     4981 ctatcaagga ccaatattta aactggtcca agatcaggtt gaattaccag aaggcaaggg
     5041 aactgcccaa cgggatttga tttttcacaa tggggctgtc tgtgttttag cagtaacgga
     5101 tgaacaaaaa cttatcttgg tcaagcagta ccgcaaagct atcgaggcag tctcttacga
     5161 aattccagcc ggaaaattgg aggtaggaga aaacacagcc cctgtcgcag ctgcccttcg
     5221 tgaattagag gaagaaacag cctatacagg gaaattagaa ctcttgtacg atttttattc
     5281 agctattggc ttttgtaatg agaagttaaa actatattta gcaagcgatt tgacaaaagt
     5341 ggaaaatccg cgtccgcagg atgaggatga aaccttggaa gtccttgaag tgagcttaga
     5401 agaagcgaaa gaattaatcc aatcaggtca tatctgtgat gccaagacaa ttatggctgt
     5461 tcagtattgg gagttgcaga aaaaatagag gaggtcagta tgggtaaatc tttattaacg
     5521 gatgaaatga ttgaaagagc taatagaggc gaaaaaattt caggtcctcc tttgctagat
     5581 gataatgagg aaactaagat tttaccaacc tcttcttccc gttttggtta tgccaatcct
     5641 aaggatcatg gttttagcca ggaaaccttg aagattcagg tcgaaccatc tattcataaa
     5701 agccgtcgta ttgaaaatac caagagaaat gtcttcaatt ctaagttgaa taaaatctta
     5761 ttcgcggtca tctttctctt gattttgctt gttttagcaa tgaaactttt gtaatagaaa
     5821 aggaattgaa atgaaaatag gaattattgc tgctatgcca gaagaactgg cttatctggt
     5881 ccagcattta gacaatgccc aggagcaagt tgttttgggg aatacctatc atacaggaac
     5941 cattgcttct catgaagtcg ttcttgtaga aagtggaatt ggtaaggtca tgtctgctat
     6001 gagtgtggcg attttggctg atcatttcca ggtggatgcc cttattaata cgggttcagc
     6061 tggggcagta gcagaaggta tcgctgttgg ggatgtcgtg attgctgaca aattagccta
     6121 tcatgacgtg gatgtcacag cttttggcta tgcttatgga caaatggcgc aacaaccgct
     6181 ttatttcgaa tcagacaaaa cctttgttgc tcaaatccaa gagagtttat ctcaattgga
     6241 ccaaaactgg catcttggtt tgattgctac aggagatagt tttgttgcag gaaatgacaa
     6301 gatagaagcg attaagtccc atttcccaga agttttagcc gtggagatgg agggggcagc
     6361 tattgctcaa gcagcgcatg ccctcaatct cccagtctta gtcatcagag ctatgagtga
     6421 caatgccaac catgaagcaa acatcttttt tgatgagttt attatcgaag ctggacgtcg
     6481 ctctgcccaa gtcttgttga cctttttgaa ggctttagat taagtggaaa tttgacagtt
     6541 tttctagctt atgataagat ttaagtaaag aaaagctaga aaacgtttca gaggatatta
     6601 tgagtattga aatgaccgtc agtgagattg cagaggtctt aggattatct cgccaagcaa
     6661 tcaataaccg tgtcaaagaa ttaccagaag aagacacaga taaaaatgac aaaggggtaa
     6721 cagttgttac cagaagtggc ttgattaagc tagaagaaat ctataaaaaa acgatttttg
     6781 aagatgaacc tgtcagtgaa gatgtcaaac aacgtgaact gatggagatt ctagtggatg
     6841 agaagaatgc agaaattctt cgtctttatg aacaattaaa agccaaggat cgtcagttat
     6901 cagaaaaaga cgagcagatg cgtatcaaag accgtcagat tgctgagaaa gacaaacaat
     6961 tagatcagca acaacaattg acccttcaag ccatgaagga tcaagaaaat cttaagctag
     7021 agctggacca agcaaaagaa gaagtccaat ccactaaaaa aggctttttt gctcgtttat
     7081 ttggaggata atcaaggagc tgtttaggtt aaatgctaac ctgatggctt cttttgtttg
     7141 tgaatagtat agttgattag aacagagaca gtagaggaga ggtacagaat ggaacgatta
     7201 gaagattaca ttgcttttga tttagaattt aatcagcatg aaggacaaac acacttgatt
     7261 caagtatcgg cagtgcgttt tagagatggt cgggaaatcg atgcctatga ttcctatgtt
     7321 cataccagcg tccctctaaa aagctttatc aatggtttga ccgggattac agctgagacc
     7381 ttaaaagatg ctcctccagt tgagaaagtc ttagaagaat tccaagagtt tgtgggttct
     7441 ttgctgatga taggctacaa tgctgctaaa agtgatttac ctattttagc agagcatggt
     7501 ttagactata gccaacagta caaggtggat ttgtatgatg aagcttttga acgtcggagt
     7561 tcagatttac atggtattgc caatctcaaa ttgcaaactg ttgcctcatt tcttggattt
     7621 caaggtcagt ctcataatag tttagaggat gctcggatga cggcgcgtgt ttacgaatcc
     7681 ttcttagagt cggatcaagc tagggaattg ttagagacag aaagtagctt atcaaacaat
     7741 ccttttggtg gcttggactt gtctcaatta tttgactagg agtgcctatg aaacctgaaa
     7801 aacctaaaaa attgggtctt aaacagattt acctcaatct tgataaaatc ctctttctat
     7861 ttttcttgat ttttatgata gtggagtatt tgtgggtacc attcaattca tggttggcta
     7921 gcttcttatt agatcagaca ggttatcttt ttatttccta taacaatgtc ttagccatcc
     7981 ttactcattc tccattgatt agtctagctt ttttagcctt gattgtaatt aactttctgg
     8041 ttgcttattt tcaaatagga ctcctcttta ttggtgctcg tcatctcctc tataatgaaa
     8101 agcgaaggct aattgagtat atccgcaagg ttttccatga aagttttgaa tttatgaaaa
     8161 agctaactgg cgctaaagcc ttgtttatct ttttctatat agctatgctg tttcctttta
     8221 tacggaaaat gctgaagatt tattatctta ataaaatcgt cattccagag tttatccaag
     8281 cttatttaga agataaatat tggatgtggt ggctgagcat cctacttcta tctcttatct
     8341 ttctctatgt ctctgtcaga ttgatgtttg cccttccgaa gattgtatat gatcagctga
     8401 ctgttcgaga agcagtgatg tttagcttgg agaaaaccaa gaagagagtt actttttatg
     8461 cttggaattt attttacatc ttgctcaaag cacatttatt attttatctt cctttgattc
     8521 ctttattatt ggctcaaact ttggtagatg atatcactca gagagagtct ctgattcttg
     8581 gtattttgaa ttttgttgtg attaaaaatc tctattatat ggctctgact tattttttgg
     8641 ttaaatttgt ttcatttttg acaggaaagg agctggatat gcttcctagg agagaaaaag
     8701 atcacatcgt gcgatggggt gtcatgactt gtgccagtct tttctttgcc ttagaaggtt
     8761 atatttatct ggaggctccc atggttcatc tacctcaact tatttctcac cgaggggttt
     8821 ccaatgcaaa tgggattcaa aatacagtag agtccttgga aactacagca caactcaaac
     8881 cagacttggt ggagacggac gtgcaggaaa caaaagatgg gcagtttgtc atgatgcatg
     8941 atgctaactt gaaaaatcta gcaggtatca ataaaagtcc tcaagactta aacttggagg
     9001 agcttaaagg gattgatatt tttgaaaatg gctaccagac taaaatttca agctttgaag
     9061 attatctcag tcgagccaac gaacttggtc aaaaattact aattgaaatt aaaaccagta
     9121 aaaaagatag tccagacatg atggaccgct ttttagcccg ttatgctgca aagctcaaga
     9181 tttatggaca tcaaatccag tctttagact accatgttgt cgaaaaagta agacagtatg
     9241 atgccgaact gccagtttat ttcatcatgc cctacaattc tgtctttcct aaaacaagag
     9301 cgacaggata tactatggag tactcaacct tggatgaata ttttgtaagc aaactatgga
     9361 caacggatca gaaactttat gtctggactg tcaatgattc agaagctatc agcaaatctc
     9421 ttcacttagg agtagatgga gtgattacag atgatttgga aaaagttcag cgggaaatag
     9481 aagtagccca agaagatcca gaatatacgg atttgctctt gaaaaaagca ttggaattct
     9541 ttgaatttta gtaataaaaa agaggaacgg ttgttcctcc catgataggt aagtattctt
     9601 gtgaatgctt gcttttttgt ggttgcaatc cgtttacgag aattgtttgt attgttcttg
     9661 tttcaattta ctttatagtg ctttgaagtt ggaatgctac actataactt ctaaaatata
     9721 gtgaaatgaa ccaaaaatag tacacaatgt ggtataatct tcttatggca tattcaatag
     9781 attttcgtaa aaaagttctc tcttattgtg agcgaacagg tagtataaca gaagcatcac
     9841 acgttttcca aatctcacgt aataccattt atggctggtt aaagctaaaa gagaaaacag
     9901 gagagttaaa ccaccaagta aaaggaacaa aaccaagaaa ggttgataga gatagactta
     9961 aaaactatct tactgacaat cccgacgctt atttgactga aatagcttct gactttggct
    10021 gtcatccaac taccatccac tatgcgctca aagctatggg ctacactcga aaaaaagaac
    10081 cacacctact atgaacaaga cccagaaaaa gtagccttat ttcttaaaaa ttttaatagt
    10141 ttaaagcacc tagcacctgt ttagattgat gaaacaggat tcgatactta tttttatcga
    10201 gaatatggtc gctcattaaa aggtcagtta ataagaggta aagtatctgg aagaagatat
    10261 cagaggattt ctttggttgc aggtctaaca aatggtgagt taatcgctcc aatgacttac
    10321 gaagagacga tgacgagcga cttttttgaa gcttggtttc agaagtttct cttaccaaca
    10381 ttaaccacac catcggttat tatagtaaaa tgaaataaga acaggacaaa tcgatcagga
    10441 cagtaaaatc gaattctaac aatgttttag aagcctatat gtactattct agtttcaata
    10501 taccataact gctcctagtc aacctgcaag tcctgtccca gctccaagct cagctccgac
    10561 tcaagatcct agagtggtag caagcgcttc ggctagctca acgagcacac aagctcaaga
    10621 gcaagttgac aagtctgaac ttcgtgcctt gagtcaagag ttagaccaac gcttgaaagc
    10681 tttggcaaca gtatctgatc caaaaatcga tgcaacccag gctgtcctcc tagatgctca
    10741 aaaagctccg gaagatagtg ccttgacaga gtaaggtctg catactgcag tagagtctgt
    10801 gaaggctgcc ttggactctc tcaaagatgt gaaagcaaat gctagcgaca gcaagcctgc
    10861 acaggacaag aaggatgcaa aacaaggaac ggaagatagt aaggattcag ataagatgac
    10921 tgaaacaaac tcagttccgg caggagtgat tgtggtcagt ctacttgccc tcctaggcgt
    10981 gattgccttc tggctgattc gccgtaagaa agagtcagaa atccagcaat taagcacgga
    11041 attgatcaag gttctaggac agctagatgc agaaaaagcg gataaaaaag tccttgccaa
    11101 agcccaaaac cttctccaag aaacccttga tttcgtgaaa gaagaaaatg gctcagcaga
    11161 gacagaaact aaactagtag aggagcttaa agcaatcctt gacaaactca agtaaaacat
    11221 gatttatgaa atgtcagacc taaaagacat tttcgttcac aaaagcagtg acgagtaatc
    11281 cttgtcgttg ctttttggct attttggggg ataagatccg ccttgactag caaaagaaaa
    11341 gattggtcca atagtgcccg atacgatttt gcgtagcaga aagcttacaa ataaaattga
    11401 atatagtaaa ataggattag aattattaag aaagttggtt ctttattgga aacgatagta
    11461 tttttaatct ctgtttttct agcaggtgtt ttatcctttt tttctccttg tatttttcct
    11521 cttctgccag tctatgctgg gattttattg gatgatcaag aaagtgcaaa aagcttttct
    11581 ttgtttggga gaaaggttct ctggtcaggc ttgattcgaa cactttgctt tatcgctggt
    11641 atctctctca ttttctttat tctaggcttt ggtgctggtt actttggtca tattctctat
    11701 gcaaattggt ttcgatatgt catgggagct attattatca ttttgggtct tcaccagatg
    11761 gaaatttttc atttgaagaa attagaagtt caaaaaagtt ttacctttaa aaaatcagat
    11821 tctaatcgtt attggtcagc ttttttactt ggtattacct ttagctttgg ttggacacct
    11881 tgtattggtc cagttttaag ttctgtttta gcacttgcgg cttctggagg caatggtgct
    11941 tggcaaggag cgatttatac tctcatttac actctgggca tggcccttcc tttcttggtc
    12001 ttgacactag cttcaggtct agtcatgcca tattttagta aaatcaagcg tcatatgatg
    12061 ctactaaaga aaattggtgg tttcctcatt gttttaatgg gaattttgtt actattagga
    12121 caagtaaatg ttctagctgg aatttttgaa taaaggagga caaatgaaaa aagtaatgtt
    12181 tgctggctta agtctcttgt cattagttgt attgatggcc tgtggtgagg aagaaactaa
    12241 aaagactcaa gcagcacaac agccaaaaca acaaacgact gtacaacaaa tttctgttgg
    12301 aaaagatgct ccagacttta cattgcaatc catggatggc aaagaagtta agttatctga
    12361 ttttaagggt aaaaaggttt acttgaagtt ttgggcttca tggtgtggtc catgcaagaa
    12421 aagtatgcca gagttgatgg aactagcggc gaaaccagat cgtgatttcg aaattcttac
    12481 tgtcattgca ccaggaattc aaggtgaaaa aactgttgag caattcccac aatggttcca
    12541 ggaacaagga tataaggata tcccagttct ttatgatacc aaagcaacca ccttccaagc
    12601 ttatcaaatt cgaagcattc ctacagaata tttaattgat agccaaggaa agattggaaa
    12661 gattcaattt ggtgctatca gtaatgcgga tgcagaagca gcatttaaag aaatgaacta
    12721 gaatcgataa aatctgatta caagatgtag tcagattttg gtaacttcta aaactaactt
    12781 ccagtttccc acaacttagc ttttagtatg agaaaaacgc gtgacatcag tggaaatccg
    12841 tcttagacta acttccactg gttttctttt tcttgatata taagggttca aaagcgaaaa
    12901 gactcagaaa aagtgcacga caaatagccc taaaacagag tcgtcttaga gtaacttcca
    12961 gttttgggag agagatggaa gttactttga gaagttacgg tagtcagatt tttttagaaa
    13021 aacattttat aaatattcac atatctccta tatttatggt aaaatagaat tatcagttta
    13081 ttttggagtc aaagatgaat atatttagaa caaagaatgt tagtttagat aaaacagaga
    13141 tgcataggca tttgaagtta tgggatttga ttttgctggg tatcggagcc atggtaggga
    13201 caggcgtctt tacaatcaca ggtactgcag ctgcaacact tgctggccca gccctagtga
    13261 tttcaatcgt tatttctgcc ttgtgtgtgg gattatcagc cctctttttt gcagaatttg
    13321 cctcgcgagt acccgctaca ggaggtgcct atagttacct ctatgctatc ttaggagaat
    13381 tccctgcctg gttggctggt tggttaacca tgatggagtt catgacagcc atatcaggcg
    13441 tagcttcggg ttgggcagct tattttaaag gcttgctctc tcaatatggg atagcccttc
    13501 ctcaggcttt aaatggtacc tttaatcctc aagcagggac atttgttgat ttattgccta
    13561 ttcttgtctt ggtcttggtg acttcgcttg ttttactaaa tgccaaggca gccttacgct
    13621 ttaattcgat tctagttatt ttgaaatttt ccgctttagc tctctttgtt ttagtaggaa
    13681 tttggaatat taagtttgat aattggagca attttgctcc ttacggcttt ggacaaatct
    13741 atggagctag tactggtatt atggctggtg cgtccttgat gttcttcggt tttttgggat
    13801 ttgaatccat ctctatggct gtagatgaag tcaagactcc tcaaaaaaat attcctagag
    13861 ggattgtctt atcgctttct atcgtaacca ttctctatgc cttggtgacc cttgttttga
    13921 ctggtgtggt tcactatagt catttaaatg tcgatgatgc cgttgccttt gcccttcgta
    13981 gtgttgggat tagttgggca gccaactatg tgtcattagt ggctatcttg accttgatta
    14041 cagtttgtat ttcgatgacc tatgccctat cgcgtatgat ttacagttta gcacgtgacg
    14101 gcttagtgcc tgctgccttt aaggaactga cgaagactag caaggtacca aagaatgcta
    14161 ctatcttgac aggtctagct tcagcagtag cagcaggaat gttcccacta gccagtattg
    14221 cagccttttt aaatatttgt accttagcct acttgatcat gctggcttat ggtctgattc
    14281 gcttacggaa agaaaaagga atgcccaaag ctggggaatt taaaacacca ttggtacctc
    14341 tgttaccaat tttatcgatc atcatttgtt tatccttcat gttacagtat aatatgaata
    14401 cctggattgc tttcctagtt gcgttgttag taggaagtat tatttacttc acttatggct
    14461 ataagcattc taccatagaa gaataaagtg aaagtctatt gagttgttga cactcagcag
    14521 atttttatat gtgaaagaaa tttcaaattt tttctaaaaa tatcttgaca gattaaattt
    14581 tcaggagtag aatatttact agttaattaa atggttaagg agttgttcat gaagaaacaa
    14641 aatttatttt tagtcctgtt aagtgtcttt cttttgtgct tgggggcttg tggtcaaaag
    14701 gaaagtcaga caggaaaggg gatgaaaatt gtgaccagtt tttatcctat ctacgctatg
    14761 gttaaggaag tatctggtga cttgaatgat gttcggatga ttcagtcaag tagtggtatt
    14821 cactcctttg aaccttcggc aaatgatatc gcagccatct atgatgcaga tgtctttgtt
    14881 taccattctc atacactcga atcttgggca ggaagtctgg atccaaatct aaaaaaatcc
    14941 aaagtgaagg tcttagaggc ttctgaggga atgaccttgg aacgtgtccc tggactagag
    15001 gatgtggaag caggggatgg agttgatgaa aaaacgctct atgaccctca cacatggcta
    15061 gatcctgaaa aagctggaga agaagcccaa attatcgctg ataaactttc agaggtggat
    15121 agtgagcata aagagactta tcaaaaaaat gcgcaagcct ttatcaaaaa agctcaggaa
    15181 ttgactaaga aattccaacc aaaatttgaa aaagcgactc agaaaacatt tgtaacacaa
    15241 catacagcct tttcttatct agcgaagaga tttgggctta atcaacttgg tattgcaggt
    15301 atctctcctg aacaagaacc aagtccacga caactaacag aaattcagga atttgttaag
    15361 acctataagg ttaaaacgat ttttacagaa agtaacgctt cttcaaaagt agctgaaact
    15421 cttgtcaaat caacaggtgt gggtcttaaa actctgaatc ctttagagtc agacccacaa
    15481 aatgacaaga cctatttaga aaatcttgaa gaaaatatga gtattctagc agaagaatta
    15541 aagtgaggaa agaatgaaaa tcaataaaaa atatctagca ggttcagtgg cagtccttgc
    15601 cctaagtgtt tgttcctatg aacttggtcg tcaccaagct ggtcaggtta agaaagagtc
    15661 taatcgagtt tcttatatag atggtgatca ggctggtcaa aaggcagaaa atttgacacc
    15721 agatgaagtc agtaagagag aggggatcaa cgccgaacaa attgttatca agattacgga
    15781 tcaaggttat gtgacctctc atggagacca ttatcattac tataatggca aggttcctta
    15841 tgatgccatc atcagtgaag aacttctcat gaaagatccg aattatcagt tgaaggattc
    15901 agacattgtc aatgaaatca agggtggcta tgtgattaag gtagacggaa aatactatgt
    15961 ttaccttaaa gatgcggccc atgcggacaa tattcggaca aaagaagaga ttaaacgtca
    16021 gaagcaggaa cgcagtcata atcataactc aagagcagat aatgctgttg ctgcagccag
    16081 agcccaggga cgctacacca cagatgatgg ttatatcttt aatgcttctg atatcattga
    16141 ggacacgggt gatgcttata tcgttcctca cggcgaccat taccattaca ttcctaagaa
    16201 tgagttatca gctagcgagt tagctgctgc agaagcctat tggaatggga agcagggatc
    16261 tcgtccttct tcaagttcta gttataatgc aaatccagct caaccaagat tgtcagagaa
    16321 ccacaatctg actgtcactc caacttatca tcaaaatcaa ggggaaaaca tttcaagcct
    16381 tttacgtgaa ttgtatgcta aacccttatc agaacgccat gtagaatctg atggccttgt
    16441 tttcgaccca gcgcaaatca caagtcgaac agccagaggt gtagctgtcc ctcatggtaa
    16501 ccattaccac tttatccctt atgaacaaat gtctgaattg gaagaacgaa ttgctcgtat
    16561 tattcccctt cgttatcgtt caaaccattg ggtaccagat tcaagaccag aacaaccaag
    16621 tccacaaccg actccggaac ctagtccaag tc
//
LOCUS       DBJKQU010000046        15328 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.046, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000046 DBJKQU010000000
VERSION     DBJKQU010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15328
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.046"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            137..439
                     /locus_tag="ACSUUC_001664"
     CDS             137..439
                     /locus_tag="ACSUUC_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HHQ8054839.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWDGHSDKGEAVAGKTSEAWIWTKFGEQVSFFYDYDD"
     gene            510..2531
                     /locus_tag="ACSUUC_001665"
                     /pseudo
     CDS             510..2531
                     /locus_tag="ACSUUC_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            2533..3174
                     /locus_tag="ACSUUC_001666"
     CDS             2533..3174
                     /locus_tag="ACSUUC_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054840.1"
                     /translation="MIELKNISKKFGSRQLFSDMNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            3278..4630
                     /gene="murD"
                     /locus_tag="ACSUUC_001667"
     CDS             3278..4630
                     /gene="murD"
                     /locus_tag="ACSUUC_001667"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HHQ8054841.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGEHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            4634..5692
                     /locus_tag="ACSUUC_001668"
     CDS             4634..5692
                     /locus_tag="ACSUUC_001668"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HHQ8054842.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            5702..6931
                     /gene="divIB"
                     /locus_tag="ACSUUC_001669"
     CDS             5702..6931
                     /gene="divIB"
                     /locus_tag="ACSUUC_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HHQ8054843.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEIEE
                     SESKEKEEQDKKLAKKAIKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYAT
                     MKDIRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQF
                     PTKFTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIK
                     AFVSELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSK
                     IKPQLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKRLEEEQKK
                     QEEESNRNQTTQRSSRR"
     gene            7164..7865
                     /gene="pyrF"
                     /locus_tag="ACSUUC_001670"
     CDS             7164..7865
                     /gene="pyrF"
                     /locus_tag="ACSUUC_001670"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HHQ8054844.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            7899..8531
                     /gene="pyrE"
                     /locus_tag="ACSUUC_001671"
     CDS             7899..8531
                     /gene="pyrE"
                     /locus_tag="ACSUUC_001671"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HHQ8054845.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            8992..9114
                     /locus_tag="ACSUUC_001672"
     CDS             8992..9114
                     /locus_tag="ACSUUC_001672"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054846.1"
                     /translation="MYYNGGGDNYIGSGTRLAMAPQFGNHVRIHTSGSWSPDSY"
     gene            9210..9974
                     /locus_tag="ACSUUC_001673"
     CDS             9210..9974
                     /locus_tag="ACSUUC_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054847.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFLAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            9974..10726
                     /locus_tag="ACSUUC_001674"
     CDS             9974..10726
                     /locus_tag="ACSUUC_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054848.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTAILFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLALLSIIIPLTVFSVHRNWRRV"
     gene            10736..11434
                     /locus_tag="ACSUUC_001675"
     CDS             10736..11434
                     /locus_tag="ACSUUC_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054849.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFLEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            11431..12078
                     /locus_tag="ACSUUC_001676"
     CDS             11431..12078
                     /locus_tag="ACSUUC_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054850.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(12165..13031)
                     /locus_tag="ACSUUC_001677"
     CDS             complement(12165..13031)
                     /locus_tag="ACSUUC_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HHQ8054851.1"
                     /translation="MKLFKPLLTVLVLAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKLFGYVDNDGSYQGYDIELGNQLAQNLGVKVKYISVDAANRA
                     EYLISNKVDIILANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDTAK
                     ADDLVVEGGKVD"
     gene            complement(13043..13800)
                     /locus_tag="ACSUUC_001678"
                     /pseudo
     CDS             complement(13043..13800)
                     /locus_tag="ACSUUC_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(13801..14478)
                     /locus_tag="ACSUUC_001679"
     CDS             complement(13801..14478)
                     /locus_tag="ACSUUC_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHQ8054852.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFRTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(14438..15118)
                     /locus_tag="ACSUUC_001680"
     CDS             complement(14438..15118)
                     /locus_tag="ACSUUC_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHQ8054853.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFG
                     NPSTLSGK"
BASE COUNT         4616 a         2655 c         3315 g         4742 t
ORIGIN      
        1 tcgatttttt ccttgacaac aaataataaa aatattattc ttatcacata agaaagcggt
       61 ttcaataaaa gagagaggag gatttatttt gttgcattgt tgctcagggt gtgctttttt
      121 tgaaagaaaa aataaaatga aaacgaaaaa acatagatta cttgctctag ctcttatttc
      181 aagttttaca ttattgggag ctgcatcagc tgctgtacaa tatccagatg gaggagtatg
      241 gacatatgga gaaggttcag gaggtggttg ggctttttca aattactatc atggtaaaaa
      301 atatcattat tcatccatcg tgagcagatg ggatggtcat tctgataaag gagaagcagt
      361 tgcaggaaaa acttcagagg cttggatttg gactaaattt ggggaacaag tatcattttt
      421 ctatgactat gacgactaat atttagtttt cttagataat tccccttgta agaaattaca
      481 gggggaattt tgtttacaag gagtctacta tgaagaaact attcatatta ttatcaactt
      541 tttttctcag cttcttcctt gcttggatta ttgtcttacg tgcgccacaa tatttatatg
      601 caagctatga ttccgtttct ttacttcgtg tcaaaaaaga tactcaggaa ccgacgcgtg
      661 aggtatttga acaggaattg gagaattttg caaactcaga acagagttta atagctagaa
      721 gaattgtaga gccgagtaag gatgggacga ctcactttac ttatgcaact tatggtcagg
      781 gaactttacc aaaagaattc caagaagcta gccaagaaag tcgtgaacgt agtgatccgc
      841 taaatagtta tctccttttg tcaggctcct tgacgaaaga aaagcttgcc gataaattag
      901 gagatttggg ttataaagca agtgctgacc gaaagatacc gccctatttt cttgcttttc
      961 gaatattact aaatcccctt attttaatta gtttagcaat atttggctta tctttctttg
     1021 ctttagtgat tatcactcgg attaaggaaa tgagagcagc aggtataaaa ctcttttctg
     1081 gtcagactct cttatccatc atgggggatt ctttatctac tgatatcaag tggctccttc
     1141 tatcagccct cctttccttc ctaggtgggg gagtcgttct ttttagtcaa ggtttgtttt
     1201 atcctatctt gttagccacc tatggttttg ggattagttt ctatctgttg tttttattgg
     1261 cgatttcaat tttactaatg cttctttatc taatgagttt gagttacaaa gcattagttc
     1321 ccgttattaa ggggagatta ccccttaaac gcctgatgat tttaacccta ttgtgtcagt
     1381 tggttgctgt ctttacagta ggatacgctg ttaagacagg tttgacgtct taccaacgat
     1441 tgaaagaact tgaaatttca aaacaagcat ggcaggatag agcagactat tatcaaattt
     1501 cttttggctt aggtgataga ggaaaagata cagaaaatca gagcaagtga tatgcctttg
     1561 ccaaggaagc aatcgaagaa gaacaagctc tttatgtaaa ggataatctg ctccattttg
     1621 ccaatccaca aggaaaaaat gaacagggag agacactgga tacctatagt ccagatgcta
     1681 atacgctcta tgttagtccc agttatttgg acaaggaaaa ggtcgtggta gatgctgaga
     1741 ccaaacagaa gttagcccat cttcaaaaag gtgagtttat cctcttgctc ccagaacatt
     1801 tgcgctctcg agaagcagaa cttaagaaag tttttgaaga aagattgagt tattatggaa
     1861 aatctggtga ggaggcaagt gctcctttgg attatgagat gaaagcgcac gttagttatc
     1921 tttcaatggg agaaaagcgg tttgtttata ataacggtga gaatcccgta tccactcagt
     1981 atttgactga tccgatttta gtggtattca cgccgacttc tacaggtgat agttttatat
     2041 ccttatctag ttggtctatc aatgctggaa aacaactctt tatcaaagga tatgagagtg
     2101 ggctagaact cttgaagaaa gctggaattt atgagcaagt atcctatctt aaagaaggaa
     2161 gaagtgttta tctaactcgt tataatgaag ttcaaactga aacagcaact ttaatcttag
     2221 gagctattgt tggaatagcc agttccttgt tactctttta ttctgtcaat cttctatatt
     2281 tcgagcaatt ccgccgagat atcttgatta aacgaatttc aggtttacga ttttttgaaa
     2341 cacatgctca gtatatggtt agccaatttg ccagttttgt atttggtgct agtctcttta
     2401 ttttaagcag tcgagacttg gtgattggct tgctcacttt attggtcttt ctagctagtg
     2461 cagttttgac gctttaccgt caagcgcaga aagaatctcg tgtttctatg acaattatga
     2521 aaggaaaata ggatgattga actaaagaat atatctaaaa aatttggaag ccgtcagcta
     2581 ttttcagata tgaatcttca ttttgaaggt gggaaaattt atgccttaat cggtacaagt
     2641 ggctgtggta agacaacact cttgaatatg attggacgat tagagccata tgacaaaggg
     2701 caaatcatat atgatggcac ttctcttaag gacattaagc cttctgtttt ctttagagat
     2761 tacttaggat acttatttca agattttggc ttaattgaaa gccaaaccgt caaagagaat
     2821 ctcaatctgg gtttagttgg taaaaagttg aaggaaaaag agaaaatctc tttgatgaaa
     2881 caagctctaa accgtgtaaa cctctcttat ttggatttga agcaacctat atttgagtta
     2941 tcaggaggag aagcacaacg tgttgcacta gcgaagataa ttttaaagga tccacctttg
     3001 atcctcgcag atgaaccaac cgcttcctta gaccccaaaa actctgagga attactttcc
     3061 atcctagaat ctttaaaaaa tccgaatcgg accattatta ttgcgaccca taatcctctg
     3121 atttgggagc aagtggatca ggtcattcga gttaccgatt tatcacatag atgatatggt
     3181 aagattcagt tagaagaaag agtcacaaac acactttgtg gcttttttat ttccataaaa
     3241 atggtaaaat agtaggagta gaaatggagt tcgagacatg aaagtaatag atcaatttaa
     3301 aaataagaaa gtccttgttt taggtttggc caagtctggt gaatctgcag ctcgtttgtt
     3361 ggacaagcta ggtgccattg tgacagtaaa tgatgggaaa cctttcgagg acaatccagc
     3421 tgcccaaagt ttgctggaag aagggatcaa ggtcattaca ggtggccatc ctttggaact
     3481 cttggatgaa gagtttgccc ttatggtgaa aaatccaggt atcccctaca acaatcccat
     3541 gattgaaaag gctttggcca agggaattcc agtcttgact gaggtggaat tggcttattt
     3601 gatttcagaa gcaccgatta ttggtatcac aggatcgaac ggtaagacaa ccacaacgac
     3661 tatgattggg gaagttttga ctgctgctgg ggaacatggt cttttatcag ggaatatcgg
     3721 ctatccagct agtcaggttg ctcaaatagc atcagataag gacacgcttg ttatggaact
     3781 ttcttctttc caactcatgg gtgttcaaga attccatcca gagattgcgg ttattaccaa
     3841 cctcatgcca actcatatcg actaccatgg gtcattttcg gaatatgtag cagccaagtg
     3901 gaatatccag aacaagatga cagcagctga tttccttgtc ttgaacttta atcaagactt
     3961 ggcaaaagac ttggcttcca agacagaagc cactgttgta ccattttcaa cacttgaaaa
     4021 ggttgatgga gcttatctgg aagatggtca actctacttc cgtggtgaag tagtcatggc
     4081 agcgaatgaa atcggtgttc caggtagcca caatgtggaa aatgcccttg cgactattgc
     4141 tgtagccaag cttcgtggtg tggacaatca aaccatcaag gaaactcttt cagccttcgg
     4201 tggtgtcaaa caccgtctcc agtttgtgga tgacatcaag ggtgttaaat tctataacga
     4261 cagtaaatca actaatatct tggctactca aaaagccttg tcaggatttg acaacagcaa
     4321 ggtcgtcttg attgcaggtg gtttggaccg tggcaatgag tttgacgaat tggtgccaga
     4381 cattactgga ctcaagaaga tggtcatcct gggtcaatct gcagaacgtg tcaaacgggc
     4441 agcagacaag gctggtgtcg cttatgtgga ggcgacagat attgcagatg cgacccgcaa
     4501 ggcctatgag cttgcgactc aaggagatgt ggttcttctt agtcctgcca atgccagctg
     4561 ggatatgtat gctaactttg aagtacgtgg cgacctcttt atcgacacag tagcggagtt
     4621 aaaagaataa aatatgaaaa aaattgtctt tacaggtggg gggacggttg gacacgttac
     4681 cctcaatctt ttgttaatgc ccaagttcat cgaagatggt tgggaagtcc actatatcgg
     4741 ggacaagcgt ggtatcgaac accaagaaat ccttaagtca ggtttggatg tcactttcca
     4801 ctccattgcg actgggaaat tgcgtcgcta tttctcttgg caaaatatgc tggacgtctt
     4861 caaagttggc tggggaatcg tccaatcgct ctttatcatg ttgcgacttc gtccacagac
     4921 ccttttttca aagggaggct ttgtctcagt accgcctgtt atcgctgcgc gtgtgtcagg
     4981 agtgcctgtc tttattcacg aatctgacct gtctatgggc ttggccaata aaatcgccta
     5041 taaatttgcg actaagatgt attcaacctt tgaacaagct tcgagtttgg ctaaggtcga
     5101 gcatgtggga gcggtgacca aggtttcgga caaaaacact ccagaaccag atgaattggt
     5161 ggatattcaa acccacttta atcccaaatt gccaactgta ttgtttgtcg gcggttctgc
     5221 aggcgctcgt gtctttaacc aattggtgac agaccataag aaagaactaa cagagcgcta
     5281 caatattatc aatttaactg gagattctag cctgaatgag ttgaggcaaa atctttttcg
     5341 tgttgactat gtgaccgatc tctatcaacc cttgatggaa ttggctgata ttgttgtgac
     5401 acgaggtggt gccaatacga tttttgagct cttggcgata gcaaaattgc atgtcattgt
     5461 gccgcttggt cgtgaagcta gtcgtggtga ccagattgaa aatgcagctt actttgtaaa
     5521 aaaaggctat gcagaagacc ttcaagaaag cgatttgacc ttggatagtt tggaagagaa
     5581 gctttctcac ttactaagtc acaaggaaga ttaccaagct aagatgaaag cttctaagga
     5641 attgaaatct ctagcagatt tttatcaatt gttgaaaaaa gatttatcat aaggaaagta
     5701 aatgtcaaaa gataagaaaa atgaggacaa agaaatcctc gaagaattga aagagttatc
     5761 agaatggcag aaacgaaacc aagaatatct aaaaaagaag gctgaagaag aggcggctct
     5821 agctgaggag aaggaaaagg aaagacaagc tcgaatggga gaagaatctg agaagtcaga
     5881 ggataaacag gaccaggaga gtgaaacaga ccaggaagat tcagaatcag ctaaggaaga
     5941 gtctgaagaa aaagtggcat cctcagaggc tgacaaagag aaagaagaaa aagaagagat
     6001 agaagaatca gagtctaaag agaaggagga acaggataaa aagcttgcta aaaaggctat
     6061 aaaggaaaaa ccagccaaag caaagattcc tggtatccat atcttgcgag ccttcacgat
     6121 tttatttcca agtctgcttt tattgattgt ctctgcctac ttgctcagtc cttatgcgac
     6181 catgaaagat attcgtgttg agggaacggt gcaaactaca gctgatgata ttcgacaggc
     6241 ttcaggcatt caggattcgg attatacgat taaccttctg ctagacaagg caaaatatga
     6301 aaagcagatt aagtctaact attgggttga atcagctcaa cttgtctatc aatttccaac
     6361 taagttcact attaaggtca aggaatatga tattgtggcc tactatattt ctggtgaaaa
     6421 tcattatcct attctttcca gtggtcagct tgagactagt tctgtgagcc tgaacagttt
     6481 accagaaact tatttatcag ttctctttaa tgatagtgaa caaatcaagg cttttgtctc
     6541 agaacttgct caaattagcc cagaactcaa ggcggctatc caaaaggtgg aattagcccc
     6601 aagcaaggtg acatccgatt taattcgatt gaccatgaat gattcggacg aagtcttggt
     6661 tcctctatct gaaatgagta agaaactgcc atattacagt aagattaagc ctcaattgtc
     6721 agaaccgagt gtggtcgaca tggaagctgg aatctacagc tacactgtgg cggataaatt
     6781 aattatggag gctgaggaaa aagccaaaca agaggccaag gaagctgaga aaaaacagga
     6841 agaagaacag aaacgtttag aagaagaaca gaaaaaacaa gaggaagaga gcaatcgaaa
     6901 ccaaacgacc cagcgctcat cgcgtcgcta ggtttacctt ttctcttata gttctttagt
     6961 gaccatgttt ttacttgaca agtgctagta gaaataatag aatagtaaaa aacctttaaa
     7021 gcagtccaga gaggcagcta aggttagacg gtgaaagggt ggagactacc catttttcgt
     7081 ggaaccttgc tgttggcagg ttcctttttt cgtggcttct gttggccaga ctctctcact
     7141 agtaaaggta aaaggagaaa cctatgcgag aacatcgtcc aatcattgct cttgattttc
     7201 ctagttttga ggcggtcaag gaatttttag ctcttttccc agcagaagaa agcctttatc
     7261 tcaaggtagg gatggagctt tattacgcag cggggcctga gattgtgtcc tacttaaaag
     7321 gtttgggtca tagtgtcttt ttggatctca aacttcatga cattcctaat acagtcaagt
     7381 cagccatgaa ggtcttgtct cagcttggtg tcgatatgac taatgtccat gcggctggtg
     7441 gtgtagagat gatgaaggcg gcgcgtgaag gtcttgggag tcaagccaaa ttgatcgctg
     7501 taacgcagct gacatcaacg tcagaagccc agatgcagga gtttcaaaat atccaaacca
     7561 gtctgcaaga gtctgtgatt cactatgcca agaagacagc tgaagctggc ttggatggtg
     7621 ttgtttgctc ggctcaggaa gtacaagtca tcaagcaggc taccaatcca gattttatct
     7681 gtctgacacc agggattcgt ccagctggtg ttgcagttgg agatcaaaaa cgagtcatga
     7741 cacctgctga tgcctatcaa atcggcagtg actatatcgt agtgggacgt cccattaccc
     7801 aagctgagga tcctgttgca gcttatcatg ccatcaagga tgaatggaca caggactgga
     7861 attaaagaac tagattagaa aaataaaagg agaataccat gacacttgct aaagatatcg
     7921 ctagccacct cttgaaaatc caagccgttt acctcaaacc agaggaaccc ttcacttggg
     7981 catctggtat caagtcaccg atttacactg ataatcgtgt gacactagcc tatccagaaa
     8041 ctcgtaccct aattgaaaat ggttttgtgg aagctatcaa agaagccttt cctgaagtag
     8101 aagtgattgc aggaactgca acagcaggga ttccacacgg agccattatt gctgataaga
     8161 tggacttgcc ttttgcctac atccgtagca aaccaaaaga ccacggagct ggtaatcaaa
     8221 tcgaaggtcg cgtagctcaa ggtcaaaaaa tggtagtggt tgaagacctt atttcaacgg
     8281 gtggttcagt tcttgaagct gtagcagcag ccaagcgaga aggagcagat gtacttggag
     8341 ttgtagcgat tttcagctac caattgccaa aagcagataa gaactttgca gatgctggtg
     8401 ttaaacttgt gacgctttca aactatagcg agcttatcca tctagcccaa gaagaaggtt
     8461 acatcacgcc agagggcctt gatcttctaa aacgctttaa agaagaccaa gaaaattggc
     8521 aagaaggtta ggtcagtaag ataaagagag acgaggctac cgagtctctt ttaccatttt
     8581 atttaaaata tgacaatatt ttaaataaaa taattgacaa cgctttcttt tattgatata
     8641 atgaaaatgt aatatgtatc aaattgatca atcaactatc ttgtttatca cttcttaaga
     8701 ggacgatgtc atgaaaagaa gaaaaatata ttcctttttt gcgtagttac aattgcatct
     8761 agtttgtttc tccctacagt tttagctaga cagattggaa attatgattt aacgttgccg
     8821 cgttggggtt cggatacaac tagtgagctt gagaaagaaa acgcctctgc tggaattaat
     8881 aatagtgaca gcactggtgg cggtaaaagg ttaagtacct ctattcgtag cgcctatagt
     8941 gggtcagata ttaccccggt atattcattg gggtctggct ctaggattgt catgtactat
     9001 aatggaggtg gtgacaatta tattggttct ggtactagat tagctatggc gccacaattt
     9061 ggaaatcatg taagaattca tacttcaggt tcttggagtc cagattctta ttaacttact
     9121 tgtcagagta agccttaaag atggttgatt gtgggtgtag catgaaaaaa gaatgctaca
     9181 ccctattttt attataagga ggagtaagga tggaattttt catttgtaat cttgtacgag
     9241 tcgttcaatc acctcgattt tatatgtctt tatttttgac ccttctttgc atgagtttag
     9301 gaaatttcct tgctttcaat ggtatttata aaattgaagg tttatcgatt ttttttgccg
     9361 cttcttctat tcgaggattt tcaccgatta gcctagtagc tgcacttatc tgtacactgc
     9421 cctattctag tcagataata gaggatgctg agagtcattt tctaacagca caattgtgcc
     9481 gaatttctaa aaagaggtat ctagctattg taggtagtac tgcaattatt tcttcttttc
     9541 tagtcttttt tctcccctat ttattattat taggaattaa tcttttagtg actccttatc
     9601 aggaaattta tattggagat tatagtggtg ccttaaaaga attatttgat tctaatcagt
     9661 tgctctatag tcttgtgacg actctctggt atggagtttg gggcgctgtg ttctctattt
     9721 ttggactagc tagtgctttg ctagtgaaga aaaaaatagg agctattttc atcccagttg
     9781 cctatatgat ggttggtggt atttttttgg ctattttagg gctatcttac ttagaacctg
     9841 tgacaacatt agctttggga tatcagaaag atatcagtct ttccttagtt agtgggcatc
     9901 ttgcttttat tttatttgtt agttgtttgg ttgtttatgg tacatttttt ctacattcag
     9961 aggactatgt ataatgaaac aatttgttca attttataaa aaagatttct tagcagtatt
    10021 ggtttatttt atattactgc tatcctgtgt tttatctagt acagtatatt tattgcgctg
    10081 tcgccaatat tcaatccatc caaatgtatt agaatggatc ttagttttac ttcaagatat
    10141 gacgactgga gtatattgct ttccgttcac atatatattg ttcttttttt atttgatgaa
    10201 taactatttt aataggttgg agtgtcgcat tcgtctgaaa tcaattaagc actttaccag
    10261 ttttagtttc aaattagcag ctcttagtac ggggatttgg acggcgattt tatttttatt
    10321 gatttttcta attgcattta gtaatggttt tagcttctct ttggagataa aggaggttga
    10381 ttttttaaga gaattttatg gcataagtat tgcaaacaat gctagtttct ttataggatt
    10441 ttttttctct tatatagcat actatttctt tttatcctta cttactatta gcagtttttc
    10501 ttggtttaaa aaatcaaaca tgagcttagt atttctgttt acttttttat ttgtagaatc
    10561 cttattctgg atttatcagt tgaacaatgg gataattgga ttattgccaa tttttcagta
    10621 tatggtaaat tccaatccgt atgcattgat ttattggctt gcattactat ctatcataat
    10681 tccattgact gtattttctg ttcatagaaa ctggaggaga gtgtaaaagt tggaaatggg
    10741 aaagttaagt agtcacatgt ggaggttgaa tcagataatc tataccaagt acttttgggg
    10801 ttatgttctt ttttggatat tgatttgttt aggattatgg tattggttag aaggaaatga
    10861 tagacttgtt atagaaattt taaaagggcc taatctgagt caaaactctt ttttagtctt
    10921 atctatatgg ttgcttcatt ggtttattat tcatacattt tttctagcag ttgtatatcg
    10981 tagaagagca tccgatttct ttctggaagt gattcgattt tcttctatta agctctggat
    11041 taggtatcag atttggacct gttttcttta tggacttatt ttaatcatgg taaaagttct
    11101 agtgattcaa tttatgttac agttaccaaa ctgggatata ggagttttgt ttatagttga
    11161 ttctttgaat gcttgtgtgc tatccttgct ttgctttatg ttatacgcac taggagcgaa
    11221 tgtacaaatg aactttgctt gcgttagttt ctttttactc atgattgtgt ttggtggtct
    11281 atttgtagga aatcgaacta attatctatt ttatattttg aatcgaggga atggagatat
    11341 aggacgagat ttatttcttc agttgctatt tttagtcttt ctttttaaaa gcattttcta
    11401 tttcactcgt caaaagagga ggtttataga atgaatgaaa taattacatt aaaaaatatt
    11461 gagttgaaat taaaaaaaac atgtgttttt caaaacctta attttagttg taaacagggg
    11521 gaaattatag gaattactgg tgcgaatggc tcaggtaaaa gtgtattgtt taaattaata
    11581 gctggtttat atagtccgtc ttatggagaa gtgttaatca atggggaaaa tattgttcct
    11641 gagagaaaaa ttccagctaa tttgggagct ttgattgaag aacctggttt tataaattat
    11701 tatagtggct ttaagaattt acaatatttg gcaagcatac gaggagtagt tggtaatcag
    11761 gaaatcaatg atacactgaa aatagttggt ctatatgagc aaaaagacca gaaagttaaa
    11821 acttattcgc taggtatgag gaaaaagcta gggattgctc aagcaattat ggagaatccc
    11881 tctattcttt tactagatga acctatgaat gccttggata aatcaagtgt agaaaatatg
    11941 agaacattgt ttagaaagct ctctagtgaa aaagggacaa caattttgat tgctagtcat
    12001 agtgaagagg atattcgtat cttatgtgat aaagtatatg caatagaaga taaagtatgt
    12061 acactgtgtt cagattgaac atcttagata gactcaggat gttataggta aaatcttaaa
    12121 aagggattgg agcttaaaat ccagttcctt ttaagagtta atgactaatc aacttttcca
    12181 ccttcaacaa ccaggtcatc tgctttagca gtgtcaccgt aggttgggtg aagtgttttt
    12241 tcataggcct tgtggaagaa gttttccttg cctaattttt caatatcttt attgatgaag
    12301 tctagcaatt cttggttgcc tttttgaact gctgccgcaa tggtatcggg atcaccgagg
    12361 gaagtaattc ctacttcaaa tcctttattt tcaagcgccc aagctagaac ttccgtatta
    12421 tcagttgaaa aggcatctcc acgtccgtca agaagagctt ggtaagagtc actgtattgg
    12481 tcgtattttt ggagtttgat ttctggatga ttcttttcaa aataagtctc agcagtcgtt
    12541 ccttttgtga caattaaggt tttaccttca agttgtttga cgtctgtaat gagaccagtc
    12601 ttaggtgata cgacacccag agaaactttc atatatggaa gggcaaaatc aacttgtttc
    12661 ttacgttcgt cagttactgt aaagttagca agaataatat ctaccttgtt tgaaatcaag
    12721 tattccgcac ggttggcagc atcgactgaa atgtatttaa ccttgacacc aaggttttga
    12781 gctagttggt tccctagttc aatatcgtag ccttggtaag aaccatcatt gtcaacgtag
    12841 ccaaacagtt ttttatctcc aaacacggcg attcgcagtt caccgctttt tttgatttca
    12901 tcgatagtgc gagctttggc agttgttttt ccagaggatg aaccagcgtt tccacctgag
    12961 ctacaagcag tgataaagat aagggcaaag gcaagtacta aaacagttaa gagtggtttg
    13021 aatagtttca taagaatctc ctttatagat atgagccgaa ttggctaaag tcaaagacgt
    13081 ttaaaaattc ctgggctcgt ttggtttgcg gattggtaaa gaaggcttga gctgttcctt
    13141 cttcagcgat tttcccttgg tcgaggaaga taatccggtc agcaatggct tgggcaaact
    13201 gcatttcgtg ggttactaaa atcatggtac ggccttcttg ggccaaatca ttgataagtt
    13261 ccagcacctc acgcaccatt tctggatcca gcgaagcagt cacctcgtca aaaaggatga
    13321 tttctggatg cattaggagg gcacggacaa ttgcaacacg ttgcttctgt ccaccagata
    13381 attgacgggc aaagctatgt tgtttatcca gcaaaccgac acgatctagt aattgcaaag
    13441 cttcttccgt tacttctttc ttgtcccttc cttgagtttt gatagggcct aggatgaggt
    13501 tttgtaagac atccagatgg ggaaagagtt cataactttg aaagaccatg ccaatctttt
    13561 ggcgaactag gtgaaaatct tttttatttt caacgataga ctgaccatcc agaaaaatat
    13621 ctccaccttg aatactttct aagccgttga ggcaacgaag gagggtactt ttcccacaac
    13681 cagatggccc taggatgaca acaacttccc ttttttgatt tctagagaaa gtcctttgag
    13741 gatgggattg tctccgaagg atttttttag ttccttgatt tctaagatag tttcagacat
    13801 ttagtttctc caatgttttt ctaagtgagt ggatagtttg gaaatagggt agcaaactgc
    13861 gaaatataag actagaatgg ttccataaat ccaaaatgaa gcagttggga tggtcaggcg
    13921 attgctatcg atgatttgtt gtccaacttt ggtcacttcc acaaccccaa tcaaaacaac
    13981 taatgaagtg gttttaatca tccgagtgac aagattgata gcctgcggta gcagtcttct
    14041 taagacttgt gggatgatga tgtggtagta aagttgaaca ttagtcaagc cgagtgcctg
    14101 tccactttca aactgatgtt tagggagaga agtgatagct ccacgtacca agtctcccat
    14161 ttcagctgtt ccccagaggg taaaaacgat aatagctgaa gtctcacctg agatattgat
    14221 attaaagttt cgagccaagc caaagtaaac gatgaagagt agcaccagct ggggcatgat
    14281 acggataaat tccagataca atcgtgttaa aaatcgtatg attctagaat gggaggtcat
    14341 gatgattccc atgactgttc tgaacatcat ggataagagg acagacagga tggatatctc
    14401 aatcgtaacg cccaatccct gtaagattct caggagatta tttccctgaa agagtacttg
    14461 gattcccgaa tcctgcatgg cggagcctcc tttctatcca gctaaagacc agtgagatgg
    14521 gtagcagcat gatcagataa gcaactacca acatagctag cgcaatgtct gtctcatagt
    14581 agagaccaat caaatccttg gcgacataca tgaggtcggc caaagccact gctgagaaaa
    14641 cagaggtttc cttgataagg aaaatgacat tggcactaaa ggaggggagt gccaccgctg
    14701 ttgcttgcgg aagaaccaca tagcgaaaga cctgtagagg tgtcagacca atagcgaggc
    14761 caatctcctg ctgggtttga ctgatggctt ccagcccact tcggaaagat tctgccatat
    14821 aggagcctcc taaaaagaca agcccaagcg ttgcacagac ttctgaagat aggacaatcc
    14881 cgattcgggg aagaccgaag tagagaaaga agagttgaat caaaaggggc gtattacgtg
    14941 acaattcaat gtaggctgtc gctacttgcg ccaaaacagg gattcgataa tgtcggatga
    15001 tactaacgat taaaccgagc agaaaggatc ccaaaattcc ccaaactgca atatgcaagg
    15061 tcagaaagaa tgccttttga tatagtggta gatattgttc aacaatggac caatccaaaa
    15121 atagaacctc ccatctagaa ataatacagt tattgtagca cttaaaatct tctttggata
    15181 atatctattt tttattgccg ttataaggat tttttaccat agacataaaa tttctgaaat
    15241 ttccaaacaa aatatttgaa aagttttgaa aaagagttaa gatatttttg taatatacaa
    15301 agtgaacgct tacttattaa ggagggca
//
LOCUS       DBJKQU010000047        14166 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.047, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000047 DBJKQU010000000
VERSION     DBJKQU010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14166
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.047"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..144
                     /locus_tag="ACSUUC_001681"
     CDS             <1..144
                     /locus_tag="ACSUUC_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HHQ8054854.1"
                     /translation="KERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHE
                     LGF"
     gene            complement(459..2150)
                     /gene="argS"
                     /locus_tag="ACSUUC_001682"
     CDS             complement(459..2150)
                     /gene="argS"
                     /locus_tag="ACSUUC_001682"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HHQ8054855.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2286..2732
                     /gene="argR"
                     /locus_tag="ACSUUC_001683"
     CDS             2286..2732
                     /gene="argR"
                     /locus_tag="ACSUUC_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HHQ8054856.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2783..5317
                     /gene="mutS"
                     /locus_tag="ACSUUC_001684"
     CDS             2783..5317
                     /gene="mutS"
                     /locus_tag="ACSUUC_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HHQ8054857.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5464..7158
                     /gene="patA"
                     /locus_tag="ACSUUC_001685"
     CDS             5464..7158
                     /gene="patA"
                     /locus_tag="ACSUUC_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HHQ8054858.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SNELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMIQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKNVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7476..7778)
                     /locus_tag="ACSUUC_001686"
     CDS             complement(7476..7778)
                     /locus_tag="ACSUUC_001686"
                     /inference="COORDINATES: protein motif:HMM:NF014430.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HHQ8054859.1"
                     /translation="MITHRRFISCNENIKHYKRLSDKAEKCVNDLMAEFNSVITTVTG
                     IENRLGAVILAEIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAERMVKRGSPHLR"
     gene            7933..9699
                     /gene="patB"
                     /locus_tag="ACSUUC_001687"
     CDS             7933..9699
                     /gene="patB"
                     /locus_tag="ACSUUC_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HHQ8054860.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9838..10527
                     /locus_tag="ACSUUC_001688"
     CDS             9838..10527
                     /locus_tag="ACSUUC_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HHQ8054861.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKHLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10531..10710
                     /locus_tag="ACSUUC_001689"
     CDS             10531..10710
                     /locus_tag="ACSUUC_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054862.1"
                     /translation="MEHLVVLFFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10697..12046
                     /locus_tag="ACSUUC_001690"
     CDS             10697..12046
                     /locus_tag="ACSUUC_001690"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HHQ8054863.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEKIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12170..13630
                     /gene="gltX"
                     /locus_tag="ACSUUC_001691"
     CDS             12170..13630
                     /gene="gltX"
                     /locus_tag="ACSUUC_001691"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HHQ8054864.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGTIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13644..14078
                     /locus_tag="ACSUUC_001692"
     CDS             13644..14078
                     /locus_tag="ACSUUC_001692"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase family protein"
                     /protein_id="HHQ8054865.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNEQ"
BASE COUNT         4160 a         2721 c         3182 g         4103 t
ORIGIN      
        1 aaggagagaa gcaaggtcga gaacatcttt gccaaagtaa aaacgtttaa aatgttttca
       61 acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgat tgctggtatt
      121 atcaatcatg aactaggatt ctagttttgc aggaagtcta ttatttggtt aggtgaatta
      181 gtgaagcgtt taggcaagtg tctctggtta cgacgtcatg gcctctaaat cgattatatt
      241 taggggtcat gactagtgaa gcagttagct agttcgcata taagcggcta gcgtctaaca
      301 attaggaact ttagttccaa taactttaag attacgacgt tttaggacat aaatcgatca
      361 tatttatgtc ctaaaactag tgaagcgcct agccaaagtc cgaataggat ttggcgttag
      421 ttacttagat tgctttgcaa tcaagtaact ttggcgattt acatcttctc tggcgcttct
      481 actccaagca agcgaagggc ttctttgaga acgactgcgg ttgcgtagct gagggctaga
      541 cggctgtcgc gttctgggct ttcatccaag atacgtgtat gtgcatagta tttgttaaag
      601 gattgagcca ggctaattgc aaatttagca atgatagaag gttcaaagtt atctgccgca
      661 cggttgataa tacgtgggaa gtcttgaatg agtttaatga tttcccagct ttcagtatca
      721 ttcaagctat agttgccagc tgtttctggt ttgaaatcgg ctttgcgtaa gatagattgg
      781 atacgagcgt aggcatattg aacgtaaggt ccagtttcac cctcgaagga taccatagct
      841 tctaggtcga agtcgtatcc atttgtacgg tcagttttga ggtcatagaa tttaatggct
      901 ccaaccccaa cagcatgtgc tacttggtct ttgttttcta gttcaggatt tttagcctcg
      961 atttggacct tggcacggct aacagcctct gcaacagtag gctctagcaa gatgacattc
     1021 cctttacgag tagagagctt cttcccttct tttgtaacca gaccaaaagg aacgtgggta
     1081 atgtcgtcac tccaatcgta gcccatctct tgcaagacag ctttgagttg tttaaagtgg
     1141 gcagattgct cttgaccaac gacgtagata gatttagcaa attggtattc atttttacgg
     1201 tagagggctg cagccaagtc acgtgtgata tagagagttg caccatcaga cttcttgatg
     1261 agggctggat gttcaattcc atatttctca agattcacaa cttgggcacc ttctgattca
     1321 agaagtagtc ctttttcaga aagaatgtct acaactgcat ccatcttatc attgtagaag
     1381 gcttctccgt tatagctgtc aaattcaacc ttcaattcat tgtaaaggcg gttaaattcc
     1441 actaaacttt catcgcggaa ccattgccaa agagcgagag cttcctcatc tccattttca
     1501 agtttacgga accattcgcg cgcttcttca tccaagctag ggtcattttc agcttcagcg
     1561 ttgatgcgga catagagttt aaggagttca tcgattggat gagcttttac agcttcttcg
     1621 tcgccccatt ttttgtaggc aacaatcaac atcccaaatt gtttacccca gtctcccaaa
     1681 tggttgacct tgaccgtttg ataaccgatt ttttggaaaa tatgtgacaa gctatctccg
     1741 ataacagttg aacgcaggtg gccaatagaa aatggtttag cgatattcgg actagacatg
     1801 tcgataacaa cattttcttg tttgccaata ttttggtcag catagtgttc tttttcagtg
     1861 gtaacagctt gcaatacttg agcagaaatg gcagatttat caaggaaaaa gttaacgtaa
     1921 ggtcctgttg cgacaacttt ttcaaaggct tggctgttca ttttttcagc cagttcagcc
     1981 gcaatcattt gtggtgcttt acgttcgact tttgcaagag aaaaagcagg gaaagcaatg
     2041 tctcccattt ctgagttttt aggggtttcc agtaacttta aaatagcctc ttggtccagg
     2101 ctatcaatga tgctagataa ttcgctagca atcaattctt ttgtattcat taagagctcc
     2161 tttttggact tttctactat tttatcacaa ttttaaagaa agaagaaaaa atttttgaaa
     2221 tctcctgttt ttttggtata atatggttat aaatatagtt ataaatatgc acgcaagagg
     2281 attttatgag aaaaagagat cgtcatcagt taataaaaaa aatgattact gaggagaaat
     2341 taagtacaca aaaagaaatt caagatcggt tggaggcgca caatgtttgt gtgacgcaga
     2401 caaccttgtc tcgtgatttg cgcgaaatcg gcttgaccaa ggtcaagaaa aatgatatgg
     2461 tgtattatgt actagtaaat gagacagaaa agattgattt ggtggaattt ttgtctcatc
     2521 atttagaagg tgttgcaaga gcagagttta ccttggtgct tcataccaaa ttgggagaag
     2581 cctctgtttt ggcaaatatt gtagatgtaa acaaggatga atggatttta ggaacagttg
     2641 ctggtgccaa taccttattg gttatttgtc gagatcagca cgttgccaaa ctcatggaag
     2701 atcgtttgct agatttgatg aaagataagt aaggtcttgg gagttgctct caagacttat
     2761 ttttgaaaag gagagacaga aaatggcgat agaaaagcta tcacccggca tgcaacagta
     2821 tgtggatatt aaaaagcaat atccagatgc ttttttgctc tttcggatgg gtgattttta
     2881 tgaattattt tatgaggatg cggtcaatgc tgcgcagatt ctggaaattt ccttaacgag
     2941 tcgcaacaag aatgccgaca atccgatccc tatggcgggt gttccctatc attctgccca
     3001 acagtatatc gatgtcttga ttgagcaggg ttataaggtg gctatcgcag agcagatgga
     3061 agatcctaaa caagcagttg gggttgttaa acgagaggtt gttcaggtca ttacgccagg
     3121 gacagtggtc gatagcagta agccggacag tcagaataat tttttggttt ccatagaccg
     3181 cgaaggcaat caatttggcc tagcttatat ggatttggtg acgggtgact tttatgtgac
     3241 aggtcttttg gatttcacgc tggtttgtgg ggaaatccgt aacctcaagg ctcgagaagt
     3301 ggtgttgggt tatgacttgt ctgaggaaga agaacaaatc ctcagccgcc agatgaatct
     3361 ggtactctct tatgaaaaag aaagctttga agaccttcat ttattggatt tgcgattggc
     3421 aacggtggag caaacggcat ctagtaagct gctccagtat gttcatcgga ctcagatgag
     3481 ggaattgaac cacctcaaac ctgttatccg ctacgaaatt aaggatttct tgcagatgga
     3541 ttatgcgacc aaggctagtc tggatttggt tgagaatgct cgctcaggta agaaacaagg
     3601 cagtcttttc tggcttttgg atgaaaccaa aacggctatg gggatgcgtc tcttgcgttc
     3661 ttggattcat cgccccttga ttgataagga acgaatcgtc caacgtcaag aagtagtgca
     3721 ggtctttctc gaccatttct ttgagcgtag tgacttgaca gacagtctca agggtgttta
     3781 tgacattgag cgcttggcta gtcgtgtttc ttttggcaaa accaatccaa aggatctctt
     3841 gcagttggcg actaccttgt ctagtgtgcc acggattcgt gcgattttag aagggatgga
     3901 gcaacctact ctagcctatc tcatcgcaca actggatgca atccctgagt tggagagttt
     3961 gattagcgca gcgattgctc ctgaagctcc tcatgtgatt acagatgggg gaattatccg
     4021 aactggattt gatgagactt tagacaagta tcgttgcgtt ctcagagaag ggactagctg
     4081 gattgctgag attgaggcta aggagcgaga aaactctggt atcagcacgc tcaagattga
     4141 ctacaataaa aaggatggct actattttca tgtgaccaat tcgcaactag gaaatgtgcc
     4201 agcccacttt ttccgcaagg cgacgctgaa aaactcagaa cgctttggaa ccgaagaatt
     4261 agcccgtatc gagggagata tgcttgaggc gcgtgagaag tcagccaacc tcgaatacga
     4321 aatatttatg cgcattcgtg aagaggtcgg caagtacatc cagcgtttac aagctctagc
     4381 ccaaggaatt gcgacggttg atgtcttaca gagtctggcg gttgtggctg aaacccagca
     4441 tttgattcga cctgagtttg gtgacgattc acaaattgat atccggaaag ggcgccatgc
     4501 tgtcgttgaa aaggttatgg gggctcagac ctatattcca aatacgattc agatggcaga
     4561 agataccagt attcaactgg ttacagggcc aaacatgagt gggaagtcta cctatatgcg
     4621 tcagttagcc atgacggcgg ttatggccca gctgggttcc tatgttcctg ctgaaagcgc
     4681 ccatttaccg atttttgatg cgatttttac ccgtatcgga gcagcagatg acttggtttc
     4741 gggtcagtca acctttatgg tggagatgat ggaggccaat aatgccattt cgcatgcgac
     4801 caagaactct ctcattctct ttgatgaatt gggacgtgga actgcaactt atgacggaat
     4861 ggctcttgct cagtccatca tcgaatatat ccatgagcac atcggagcta agaccctctt
     4921 tgcgacccac taccatgagt tgactagtct ggagtctagt ttacaacact tggtcaatgt
     4981 ccacgtggca actttggagc aggatgggca ggtcaccttc cttcacaaga ttgaaccggg
     5041 accagctgat aaatcctacg gtatccatgt tgccaagatt gctggcttgc cagcagacct
     5101 tttagcaagg gcggataaga ttttgactca gctagagaat caaggaacag agagtcctcc
     5161 tcccatgaga caaactagtg ctgtcactga acagatttca ctctttgata gggcagaaga
     5221 gcatcctatc ctagcagaat tagctaaact ggatgtgtat aatatgacac ctatgcaggt
     5281 tatgaatgtc ttagtagagt taaaacagaa actataaaac caagactcac tagttaatct
     5341 agctgtatca aggagacttc tttgacaatt ctccactttt ttgctagaat aacatcacac
     5401 aaacagaatg aaaaggagct gacgcattgt cgctcccttt tgtctatttt ttaaggagaa
     5461 agtatgctga ttcagaaaat aaaaacctac aagtggcagg ccttggcttc gctcctgatg
     5521 acaggcttga tggttgctag ttcacttctg caaccgcgtt atctgcagga agtattagac
     5581 gccctcctta ctgggaaata tgaagctatt tatagtatcg gggcttggtt gattggtgtg
     5641 gccgtagtcg gtctagttgc tggtggactc aatgttgtcc tcgcagccta tattgcccaa
     5701 ggagtttcat ccgaccttcg ggaggatgcc ttccgtaaaa ttcaaacctt ttcttatgct
     5761 gatattgaac aatttaatgc gggaaatcta gtcgttcgaa tgacaaatga tatcaaccag
     5821 attcagaacg ttgtcatgat gaccttccaa attcttttca gacttcccct cttgttcatc
     5881 ggttcgttta tcctagcggt tcaaacctta ccttctctgt ggtgggtgat tgttctcatg
     5941 gtagtcttga tttttggttt gactgctgtc atgatgggaa tgatggggcc tcgttttgct
     6001 aaatttcaaa cccttcttga gcgcatcaat gccattgcca aggaaaattt acgtggcgtt
     6061 cgtgtggtca agtcctttgt ccaagaaaaa gagcaatttg ctaagtttac agaggtctca
     6121 aacgagcttc ttggtcaaaa cctttacatt ggttatgcct tttcagtagt ggaacccttt
     6181 atgatgttgg ttggttacgg ggcggtcttc ctctctattt ggctggtcgc gggaatgatt
     6241 cagtcggatc cgtctgttgt tggttccatc gcttcttttg ttaattacct aagccagatt
     6301 atctttacca ttgttatggt tggatttttg ggaaattctg tcagccgtgc catgatttcc
     6361 atgcgtcgta ttcgagaaat tcttgacgca gagccagcta tgaccttcaa ggatatccca
     6421 gatgaagagt tggttggaag tcttagcttt gaaaatgtga cctttaccta tccaatggac
     6481 aaggaaccga tgctgaaaaa tgtgagcttt actattgaac ctggtcaaat ggttggtgta
     6541 gttggagcga ctggtgcagg aaagtcaacc ttggctcaat tgattccacg tctctttgat
     6601 ccacaggacg gggccattaa aattggtggc aaggatattc gagaagtgag tgaaggaacc
     6661 ctgcgtaaaa cagtttccat cgttctccaa cgtgccattc tttttagtgg aacgattgca
     6721 gataacttga gacaggggaa gggaaatgct accctatttg aaatggagcg cgcagccaat
     6781 attgcccagg ctagtgaatt cattcatcgt atggagaaaa cctttgaaag tccagttgaa
     6841 gaacggggaa ccaatttctc tggtggacaa aaacaaagga tgtcgattgc gcgtgggatt
     6901 gtcagcaatc cacgtattct gatttttgac gattcgacct cagccttgga tgccaaatca
     6961 gagcgcttgg tgcaagaagc tttgaataag gacttgaagg ggacgacaac cattattatt
     7021 gctcaaaaaa ttagctcggt tgtccatgca gacaagatct tggttctaaa tcaaggacga
     7081 ttgattggtc aaggtacgca tgcagacttg gttgccaaca atgccgttta ccgtgaaatc
     7141 tatgaaacac agaaatgaaa gacaaactat aagaaaagtc aatagtttta tctaaactat
     7201 ttcttatttc aatttgatga tttggcgatg attttagagc acggcaaaaa gcccttgaaa
     7261 aagtccattt tttcaaaggt aatcctgtgt tgatttcaga aattacatca ctttttgttc
     7321 gtcaaatggc agctcttttt taggatataa aacagggttc ggataagttt ttttgcaagg
     7381 tggatgatgg ctacattgta atgttttcct tgttctaact tagtcttaaa agcaggtgaa
     7441 aagtgagggc atgctttggc agcttgtatg agtacctacc gcagatgagg ggaaccccgt
     7501 ttgaccattc tttctgctaa atcaatctga cctgactgat aaatagaaga atccagtcca
     7561 gcgaaagctt gtaattgagc aggattatca aaggcatgaa tatttcgaat ctcggctaaa
     7621 atgaccgccc ctaaacgatt ctcaatccca gtaaccgtcg tgatgaccga gttgaactca
     7681 gccatcaagt cattgacaca tttttccgcc ttgtcactga gcctcttgta atgtttgatg
     7741 ttttcattac acgagataaa acgtctatgc gttatcaaac tcattaccaa ttaaaacaaa
     7801 tgtggttaga tcctttcgga aattgtcaag cgattggagg aaatgaacta atccacagcg
     7861 gcttattcca agtataccac ttgggctttg gcagtagcta actgcgctaa atataatata
     7921 aggaggagta aaatgaagac agttcaattt ttttggcatt attttaaggt ctacaagttc
     7981 tcatttgtag ttgtcatcct gatgattgtt ctggcgactt ttgcccaagc cctctttcca
     8041 gtcttttctg gacaagcggt gacgcagcta gccaatttag ttcaagctta tcaaaatggc
     8101 aatccagaac ttgtatggca aagcctatca ggaatcatgg tcaatcttgg cctgctggtt
     8161 ttggttctat ttatctctag tgtaatatac atgtgtctca tgacgcgcgt gattgcagaa
     8221 tcgaccaacg agatgcgcaa aggtctcttt ggtaagcttg ctcagttgac ggtttctttc
     8281 tttgaccgtc gacaagatgg cgatatcctg tctcatttta ccagtgattt ggataatatc
     8341 ctccaagcct ttaacgaaag cttgattcag gtcatgagca atattgtttt atacattggt
     8401 ctgattcttg tcatgttttc gagaaatgtg acgctggctc tcatcactat tgccagcacc
     8461 ccattggctt tccttatgct gattttcatc gtgaaaatgg cacgtaaata caccaacctc
     8521 cagcagaaag aggtagggaa gctcaacgcc tatatggatg agagcatctc aggccaaaaa
     8581 gccgtgattg tgcaaggaat tcaagaggat atgatggcag gatttcttga acaaaatgag
     8641 cgcgtgcgca aggcaacctt taaaggaaga atgttctcag gaattctttt ccctgtcatg
     8701 aatgggatga gcctgattaa tacagccatc gtcatctttg ctggttcggc tgtacttttg
     8761 aatgataagt ctattgaaac aagtacagcc ctaggtttga ttgttatgtt tgcacaattt
     8821 tcacagcagt actaccagcc tattatccaa gttgcagcga gttggggaag ccttcagttg
     8881 gcctttactg gagctgaacg aattcaggaa atgtttgatg cagaggagga aatccgacct
     8941 gaaaaggctc caaccttcac taagttgcaa gaaagtgttg aaatcagtca tatcgatttt
     9001 tcatacttgc ctgataaacc tattttgaaa gatgtcagca tttctgcccc taaaggccag
     9061 atgacagcag ttgttgggcc gacaggttca ggaaaaacga ctattatgaa cctcatcaat
     9121 cgcttttatg atgttgatgc tggtggtatt tattttgatg gtaaagacat tcgtggctat
     9181 gacttagata gtcttagaag caaggtggga attgtattgc aagattcggt cttgtttagc
     9241 ggaacgattc gagacaatat ccgatttggt gtgccagatg ctagtcagga aatggttgag
     9301 gtagcagcaa aagcaaccca cattcacgac tatatcgaaa gtttgcctga taagtacgat
     9361 actcttattg atgatgacca gagcatcttt tcaacagggc agaagcaatt gatttcaatc
     9421 gctcgaaccc tgatgacaga tccagaagtt ctcattctcg atgaagcaac ttcaaacgta
     9481 gatacggtga cagaaagcaa gattcagcat gccatggagg tggttgtagc aggtagaact
     9541 agtttcgtca ttgcccaccg cttgaaaacc attctcaatg cagatcagat tattgtcctt
     9601 aaagatggag aagtcattga acgtggtaac caccatgaac ttttgaagct aggtggtttt
     9661 tattcagaac tctatcacaa tcaatttgtt ttcgaataag aaagaagttg tcctatgtgg
     9721 gcagcttttt cttgtccata aaaaatgttt atcacagcct taaaaaaaac atattagacg
     9781 aaagtcattt tgagtgatat gataggacta tcgttagcat tcgaaaggag aggcatcatg
     9841 gctagaacgg ttgtaggagt tgctgcaaat ctatgtcccg tagacgcaga aggcaaaatc
     9901 attcattcat ctgtatcttg tagattcgca gagatcattc gtcaagtcgg tggtctccct
     9961 ttagtcattc ctgttggtga tgagtcagtt gtacgtgatt atgtggaaat gattgacaaa
    10021 ctcattttga caggaggcca aaatgttcat cctcagtttt atggagagaa aaagaccgtc
    10081 gagagcgatg attacaatct ggtccgtgac gaatttgaat tggcactctt gaaggaagcg
    10141 cttcgtcaga ataaaccaat tatggcaatc tgtcgcggtg tccaacttgt caatgttgcc
    10201 tttggtggaa ccctcaatca agaaatcgaa ggtcactggc aaggactacc tttcgggaca
    10261 tctcactcta ttgagacagt agaaggaagc gtggtggcta agctatttgg gaaagaaagt
    10321 caggtcaact cagtccatcg tcaaagcatt aaacatttgg cacctaattt ccgtgtaact
    10381 gctattgatt caagagacca aactattgaa gcgattgagt ctatcgacga gcaccgcatt
    10441 atcggtttac agtggcatcc agagtttctg gttaatgaag aagatggcaa tttagaatta
    10501 tttgagtatt tattgaatga actgtaacga ttggaacatc tggtcgttct tttttttatt
    10561 ttttcaaaat ttttagaatg tggtatttta cgcaaacgtt tgaattctga taaaaattgg
    10621 agaaattcga caaaaaaact tgaaaaaaac gaaggtaagc gttatgatag aaaagaagaa
    10681 atattggagg aagaacatgt cacatattaa atttgattat tcaaaagttt tagacaaatt
    10741 tgttgcacca catgaagtgg aatacatgca atcacaagta acagcagcag atgaattgat
    10801 ccgtaaagga actggtgctg gtagcgactt cttgggatgg ttggaccttc ctgaaaaata
    10861 cgatcgcgaa gaatttgacc gcatcttgaa agctgctgag aaaatcaagt cagacagcga
    10921 tgttttggtt gtgatcggta ttggtggatc ttaccttggt gcaaaagcag caatcgactt
    10981 cttgaatcac cattttgcta acttgcaaac aaaagaagaa cgcaaagctc cacaaatcct
    11041 ttacgcagga aactcaatct catctactta ccttgctgac ttggtagagt atgttgcaga
    11101 caaggacttc tcagtaaacg taatttctaa atcaggtaca acaactgaac cagcgattgc
    11161 tttccgtgtc tttaaagaac tcttggttaa gaaatacggt caagaagaag ctaacaagcg
    11221 tatctatgca acaactgacc gccaaaaggg tgctgttaag gttgaagcag acgctaacgg
    11281 ttggggaaca tttgttgttc cagatgatat cggtggacgc ttctcagtat tgacagccgt
    11341 tggtttgctt ccaatcgcag catcaggagc tgacatcaaa gctcttatgg aaggtgcgaa
    11401 tgcagctcgc aaagactaca cttcagacaa aatctctgaa aacgaagctt accaatacgc
    11461 agccgttcgt aacatccttt atcgtaaagg ctatgcaact gagatcttgg taaactatga
    11521 gccatcactt caatacttct cagaatggtg gaaacaattg gctggtgaat cagaaggaaa
    11581 agaccaaaaa ggtatctacc caacttcagc caacttctca actgacttgc actcacttgg
    11641 tcaatttatc caagaaggaa ctcgtatcat gtttgaaaca gttgtccgtg ttgacaaacc
    11701 tcgtaaaaac gtgcttattc ctactttgga agaagacctt gacggacttg gttaccttca
    11761 aggaaaagac gttgactttg taaacaaaaa agcaactgac ggtgttcttc ttgcccacac
    11821 agatggtgat gtaccaaaca tgtatgtgac tcttccagag caagacgctt tcactcttgg
    11881 ttacactata tacttcttcg aattggcaat tgccctttca ggttacttga atgctatcaa
    11941 cccatttgac caaccaggtg ttgaagctta taaacgtaac atgtttgccc ttcttggaaa
    12001 accaggattt gaagaattga gcaaagaact taacgcacgt ctataataga agaaaagagt
    12061 ggtttgccca ctctttttac tctctttatc catagaaatt ggactcagcc aagacttgtg
    12121 atataatata gaaagcaaaa aggcagacgc ctagataata ggagaaacta tgtcaaaaga
    12181 tatccgcgta cgttacgcac caagtccaac aggactacta cacatcggaa atgctcgtac
    12241 agcattgttt aattacttgt atgcgcgcca tcatggtgga acatttctca tccgtatcga
    12301 agatactgac cgtaaacgcc atgtcgagga tggtgaacgt tcacaacttg aaaaccttcg
    12361 ctggttaggc atggattggg atgaaagtcc agaatcacat gagaattatc gccagtctga
    12421 gcgtttggac ttgtatcaaa aatacatcga ccaactatta gctgaaggaa aagcctacaa
    12481 atcttacgtt acagaagaag agttggcagc tgaacgtgaa cgtcaagaag tagctggcga
    12541 aacaccacgc tacatcaatg aataccttgg tatgagtgaa gaagaaaaag cagcttacat
    12601 cgcagaacgt gaagcagcag ggaccatccc aactgttcgt ttggctgtca atgagtcagg
    12661 tatctacaag tggcatgata tggtcaaagg cgatatcgaa tttgaaggtg gcaatatcgg
    12721 tggtgactgg gttatccaaa agaaagacgg ttacccaact tacaactttg ccgttgttat
    12781 cgatgaccac gatatgcaaa tctctcatgt tatccgtgga gatgaccata ttgctaatac
    12841 accaaaacag cttatggtct atgaagctct tggttgggaa gctccagagt tcggtcacat
    12901 gaccttgatt atcaactctg agactggtaa gaagttatct aaacgtgata ctaatacact
    12961 tcaatttatc gaagattacc gaaagaaagg ttaccttcca gaagcagtct ttaattttat
    13021 tgctcttctt ggttggaacc caggtggtga agatgagatt ttctctcgtg aagaactcat
    13081 taaacttttt gatgaaaacc gcctcagcaa gtcaccagca gcctttgatc agaaaaaact
    13141 agactggatg agcaatgatt atatcaagaa tgcagacctt gaaaccatct ttgaaatggc
    13201 aaaaccattc ttagaggaag caggccgttt gactgacaag gctgaaaaat tagttgagct
    13261 ctataaacca caaatgaaat cagtagatga gattatccca ttgacagatc ttttcttctc
    13321 agatttccca gaattgacag aagcagagcg cgaagtcatg acgggtgaaa cagttccaac
    13381 agttcttgaa gcattcaaag caaaacttga agcgatgaca gatgataaat ttgtgacaga
    13441 aaatatcttc ccacaaatta aagcagttca aaaagaaaca ggtattaaag ggaaaaatct
    13501 tttcatgcct attcgtatcg cagtttcagg cgaaatgcat gggccagaat taccagatac
    13561 aattttcttg cttggacgtg aaaaatcaat tcagcatatc gaaaacatgc taaaagaaat
    13621 ctctaaataa agaggataca ataatggaca tctgggaaaa gatgtacgaa gaagcacaga
    13681 aactatacaa tccacatgaa gtatcagact ttgtttatgc caatcatgtt gtagctgcag
    13741 tagaagcaga agatggacaa atatttacag gattctgtat ggagggaacc tgtggtgttt
    13801 tccatctctg cgcagaacgg gcggccctct tcaatatgta ccaattttca ggacaaacta
    13861 aggttaagaa agtattagcc tttcgagata aaccacctta tggtggaagt tcagccatgc
    13921 cttgcggtgc ttgtagagaa ttccttttag agcttaatgc tgaaaataaa gatgcagaat
    13981 tcatgatgga ctataatata agaaaaacag ttaaagtcgc agaactaatc ccttattggt
    14041 ggggagaaga acgtgcttct aagtttaatg agcaatagaa gagtcagtat aattctggct
    14101 ctttttacta taagtttcaa aaaaaatgaa aaaaattaga aaaagtagtt gacaaagttt
    14161 gaaaag
//
LOCUS       DBJKQU010000048        13316 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.048, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000048 DBJKQU010000000
VERSION     DBJKQU010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.048"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(<1..425)
                     /locus_tag="ACSUUC_001693"
     CDS             complement(<1..425)
                     /locus_tag="ACSUUC_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S cluster-binding domain-containing
                     protein"
                     /protein_id="HHQ8054866.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYT"
     gene            547..1293
                     /locus_tag="ACSUUC_001694"
     CDS             547..1293
                     /locus_tag="ACSUUC_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHQ8054867.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            1306..2286
                     /locus_tag="ACSUUC_001695"
     CDS             1306..2286
                     /locus_tag="ACSUUC_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HHQ8054868.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            2481..2801
                     /locus_tag="ACSUUC_001696"
     CDS             2481..2801
                     /locus_tag="ACSUUC_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHQ8054869.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            2847..3155
                     /locus_tag="ACSUUC_001697"
     CDS             2847..3155
                     /locus_tag="ACSUUC_001697"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHQ8054870.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            3172..4470
                     /locus_tag="ACSUUC_001698"
     CDS             3172..4470
                     /locus_tag="ACSUUC_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHQ8054871.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            4621..7059
                     /locus_tag="ACSUUC_001699"
     CDS             4621..7059
                     /locus_tag="ACSUUC_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HHQ8054872.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            7078..7746
                     /locus_tag="ACSUUC_001700"
     CDS             7078..7746
                     /locus_tag="ACSUUC_001700"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HHQ8054873.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            7764..8852
                     /locus_tag="ACSUUC_001701"
     CDS             7764..8852
                     /locus_tag="ACSUUC_001701"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HHQ8054874.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            9307..11808
                     /gene="leuS"
                     /locus_tag="ACSUUC_001702"
     CDS             9307..11808
                     /gene="leuS"
                     /locus_tag="ACSUUC_001702"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HHQ8054875.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGDVKEAAYTEDGLHVNSDFLDELNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            12108..12801
                     /locus_tag="ACSUUC_001703"
                     /pseudo
     CDS             12108..12801
                     /locus_tag="ACSUUC_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144882.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            12813..13229
                     /locus_tag="ACSUUC_001704"
                     /pseudo
     CDS             12813..13229
                     /locus_tag="ACSUUC_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         4274 a         2079 c         2811 g         4152 t
ORIGIN      
        1 gtgtagataa aatccacata ttgaattaaa tcaataaatt tttcatgatc aacaaaggca
       61 gtagtttcaa tggcagtgtg tatgtgatgt tctttagctg attttaagat agctttagca
      121 aattcaaact gagcaaatat ttcacctcct gataaagtta aacctccacc ggattcttcg
      181 taaaattctt tgtcttttaa tacctctgta ataatttctt ctacagtctt ttcttcaccg
      241 actaaggtga atttctctcg ttgagcatct ttcatttttt caggtttcat tctttgagat
      301 tcaggattag aacaccatgg acagcgcaga ggacatcctt ttaaaaaaac agttgtacga
      361 atacccgggc cgtcatgaat tgaaaagtgt tgaatattaa aaataattcc tttagatatt
      421 tccataagag ttcctcctct tcataagtct atcctatcac aaaaacgaaa gaaaaacaat
      481 tacgaacgaa aggttaattt gttgtttttt gctttttatt ttggtaggat aaaacggagg
      541 tgtaaaatga aaagattgga acaaattatt aaattagtat cagaatatga aaagatcgac
      601 gttaatacat tatcggaaaa attaaatgta tcgaaagtaa cgattagaaa agatttagat
      661 aaattagagt caaaaggttt attacacaga gagcatggat atgctgtatt aaatagtgga
      721 gatgacttaa atgtacgttt gtcaattaat tatgaaatta agagaaaaat tgttcaggaa
      781 gcagtaaaat tggtgtcaga taatgaaacg ataatgatag aatctggatc gacctgtgct
      841 ttacttgctg aggaaatttg caagcaaaaa agaaatgtta cgattgtaac aaattcattt
      901 tttatagcaa attttgtgag agcttatgat tcatgtcgta ttattgttct tggtggagag
      961 tttcagaagg attcacaggt tactgtggga cctttattaa aagaaatgat acagactttt
     1021 catgtgcatc aagcttttgt tgggacagat ggatacgata aagagatggg ctttacagga
     1081 aaagatttaa tgcgcagtga ggtagttcaa tatatttcag cagcgtcgga taaagtcatt
     1141 gtcctaactg actcaagtaa atttgataaa aggggtacag taagaagatt tgctttaagt
     1201 caagtctatg aagtaataac agacgaaaaa ctttctaaac aaaatatagc tacattagaa
     1261 aatgctggga taatggttaa ggtagtttcg taagaggtta agtgtatgaa tcaagatagg
     1321 aataaactgc tctctaaaat tgcttatctg tattatattg aaaacttaaa tcagtcacaa
     1381 atagcagcaa aattaggaat ttatagaacc tctattagta gaatgttaac agaagcaagg
     1441 aatgcaggaa ttgttaaaat tgaaatagag aattttgata ccaatatgtt taagttggaa
     1501 aattatgtaa aagaaaaata tggtctggaa agtttagaaa ttattccaaa tgaatttgat
     1561 gataatccaa caattttatc tgaaagaatt tctcaagttg cagcaggtgt ccttaggaat
     1621 ctaattgatg ataatatgaa aattggcttt tcttggggga aaagtttaag taatttagta
     1681 gatttaattc acagtaaaag tgtccgaaat gttcacttct atcctctagc aggtggtcct
     1741 agtcacatac acgctaaata ccatgtgaat acactgattt atgaaatgtc tagaaaattt
     1801 catggagagt gtacatttat gaatgcaacg attgtgcaag aaaataaatt gttagcagat
     1861 ggtattttgc aatcaagata ttttgaaaat ttgaaaaata gttggaaaga tttagatata
     1921 gctgtagtcg gaattggtga ttttagcaat aaaggaaagc atcaatggtt agacatgctt
     1981 acagaggatg actttaaaga attgaccaaa gttaaaactg taggagaaat ttgttgtcga
     2041 ttttttgatt caaaaggtaa agaagtctat gaaaacttac aggaaagaac gatagcaatc
     2101 tctttggaag atttaaaaaa tattcctcaa agtttagctg ttgcttacgg tgatacgaaa
     2161 gtatcttcga ttctttctgt cttgcgtgct aatttagtaa atcatttgat tacagacaaa
     2221 aatacaattt taaaagtttt ggaagaagat ggggatttga cttttagaga gattctaggt
     2281 gagtgaaaat gatagactga ttcagtttat cgtttttctt tttagttgat tgcacatttg
     2341 tgcttatata aacaaaaata gtttatctgt tgtttttgga ttgacaactt tattatgtag
     2401 ttgtattcta tagttacaaa agaaaatttt aaaatttcaa atgaaaaaag ctttttacat
     2461 agtgaaatga ggaggaattt atggaaatta ttgttccaga tcaaattatc atgggtttaa
     2521 ttttatatgc tggtgatgcg aaacaacata tttataaagc gttagattac ataaaaaatg
     2581 gtacatgtga acggtgtgaa gaagaaatcc agttagctga tgccgcctta ttagaagccc
     2641 ataatctaca aacaaaattc ttggcacaag aagcgtctgg tacaaagaca gaaattacag
     2701 ctctctttgt tcattcacaa gatcatctca tgactagtat gacggagatt aatttaatca
     2761 aagaaattat tagtttgaga aaagaacttc ataaaaaata atactagagt attatcattg
     2821 ttattaacat agaggaggaa aacataatgg tgaagattgg tttgttttgt gcagcaggtt
     2881 tttctactgg tatgcttgta aataatatga aaattgcagc gcaatctagt ggagttgagg
     2941 cagaaataga ggcgttttct cagtctaaat tagcggatta tgcgccaaat atagatgttg
     3001 cactattggg tccacaagtt gcttatacat tagataaatc aaaagaaatt tgtgataagt
     3061 gtgatgttcc gatagctgtt attccgatga tggactatgg tatgttagat gggaaaaaag
     3121 tattagattt ggccctatct ttgattagtg ggtaagaaaa ggagatttat tatgtcaaag
     3181 atggatgttc agaaaatcat tgcaccgatg atgaagtttg tgaatatgcg tggcattata
     3241 gctctaaaag atgggatgtt agcaattttg ccattgacag tagttggtag tttgttcttg
     3301 attatgggac aattgccgtt cgaaggatta aataagagca ttgctagtgt ttttggagct
     3361 aattggacag agccgtttat gcaagtatat tcaggaactt ttgctattat gggtctaatt
     3421 tcttgttttt caattgccta ttcttatgct aagaatagcg gagtagaggc tttaccagct
     3481 ggagttctat ctgtatctgc attctttatt ttgctaagat catcttatat ccctaaacaa
     3541 ggtgaggcga ttggggacgc tattagtaaa gtttggtttg gaggccaagg aattatcggt
     3601 gctatcatta taggtttggt agtaggaagt atttatacct tctttataaa gagaaagatt
     3661 gttattaaga tgccagaaca agttccacaa gctattgcca aacagtttga agcaatgatt
     3721 ccagcatttg taattttctt atcttctatg attgtatata ttttagcgaa gtcattgact
     3781 aatggcggaa cattcataga aatgatttat tctgctattc aagttccgtt gcaaggttta
     3841 actggatctt tgtatggtgc tattggaatt gcattcttta tatcattttt gtggtggttt
     3901 ggtgttcatg ggcaatcggt agtaaatgga gtagtgacag ctcttctttt atctaatctt
     3961 gatgctaata aagctatgtt agcctctgct aatctatcat tagaaaatgg agcacatatt
     4021 gttactcaac agtttttaga ttcattttta attctatcag gttcagggat tacgtttggt
     4081 cttgtagttg ccatgctttt tgcagcaaaa tcaaaacaat accaagcctt aggaaaagtt
     4141 gcagcttttc cagcaatatt taacgtaaat gagccagttg tatttggatt tccgattgtc
     4201 atgaatccag ttatgtttgt acctttcatt cttgttcctg tacttgcagc tgtgatagta
     4261 tatggagcta ttgcaacagg tttcatgcag ccattctcag gggtaacatt gccttggagt
     4321 acaccagcta ttctatcagg atttttggtg ggtggatggc aaggtgttgt gactcagtta
     4381 ttagtattgg tgatatctac agtggtttac tttccattct ttaagataca agatcgttta
     4441 gcttaccaaa atgaaatcaa acaatcttag aggtatttgt gtgttactgt taaactcaca
     4501 catttgtgct aaaaattaga gagttaaaat ttttctagtt aaaagcttga aaatttctat
     4561 aaaaatcggt attatatttt cgaaagaaat aaaaatattt tcgaaagaaa ggtgcttacg
     4621 atggtaaata cagaagtagc aagaacaaca atcaagacag aatattttgg cagccttact
     4681 gaaaggatga acaaatatcg agaagatgtt ttaaataaaa aaccttatat tgatgctgag
     4741 agagcagttc tagcaacacg cgcctatgaa cgatacaagg aacaacctaa tgtcctaaaa
     4801 cgtgcatata tgctgaaaga aattttggaa aatatgtcta tctatattga agaagaatct
     4861 atgattgcgg gaaatcaagc ttcttccaat aaagatgctc ctatttttcc ggaatatacg
     4921 ctagaatttg ttctcaatga gttggatctt tttgaaaagc gtgatggaga tgttttctat
     4981 attacagaag aaacaaaaga acaacttaga agtattgctc cgttttggga aaataataat
     5041 ttacgtgcta gagctggtgc cttattacct gaagaagtgt ctgtttatat ggaaacagga
     5101 ttcttcggta tggaaggtaa gatgaattct ggagatgctc acttagcagt taactatcag
     5161 aaacttttgc aatttggttt aagaggtttt gaagagcggg ctcgtaaagc aaaagtagct
     5221 ctagatttaa cagatccagc aagtattgat aaatatcatt tttacgactc tatatttatc
     5281 gtaatcgatg ctattaaagt atatgcaaag cgctttgttg ctcttgctaa aagtttagcc
     5341 gaaaatgcaa atcctaaacg taagaaagaa ttacttgaga ttgcagatat ttgctctaga
     5401 gtcccatatg aaccggcaac tacttttgca gaagctattc aatcagtttg gtttattcaa
     5461 tgtattttac aaattgaatc taatggccac tctctttcat atggccgttt tgatcaatat
     5521 atgtatccat atatgaaggc tgatttagaa agtggtaaag aaacagaaga tagcattgtt
     5581 gaacgtctga caaatctttg gattaagaca attacaatta ataaggttcg cagtcaatca
     5641 catacatttt cttcagcagg aagtccttta tatcaaaatg ttacaattgg tggacagact
     5701 cgagataaga aggatgctgt taacccatta tcttatttgg tcttaaaatc agttgcacaa
     5761 acccatctac cgcaacctaa tctaactgta cgttaccatg caggtttaga tgctcgtttc
     5821 atgaatgagt gtattgaagt gatgaaactt ggttttggta tgcctgcatt taataatgat
     5881 gagattatta ttccttcttt tattgcaaaa ggagtattgg aagatgatgc ttatgattac
     5941 agtgccattg gatgtgttga aacggcagtt ccagggaaat ggggctatcg ttgcacaggt
     6001 atgagttata tgaacttccc taaggttcta cttatcacga tgaatgatgg aattgatccg
     6061 gcttcgggta aacggtttgc accaagcttt ggtcatttta aggatatgaa gaacttttct
     6121 gaattagaaa atgcttggga taaaacacta agatatttga cacgaatgag tgttattgtt
     6181 gaaaattcta ttgatttatc attggaacga gaagttcctg atattctatg ttcagcattg
     6241 actgatgatt gtattggtcg tggaaaacac cttaaagaag gtggagcagt atatgattat
     6301 atatcaggat tgcaagttgg aattgcaaat ttgtcggatt cattagctgc aattaaaaaa
     6361 ttggtgtttg aggaagaacg tataagccca agtcagcttt ggcatgcact ggaaacagat
     6421 tatgccggag aagaaggtaa ggtcattcaa gaaatgttga ttcatgatgc acctaagtat
     6481 ggtaatgatg atgattatgc tgacaaattg gttactgctg cttatgacat ttatgttgat
     6541 gaaattgcta aatatcctaa tacacgttat ggaagagggc ctattggagg aattcgttat
     6601 tcaggaacat cttctatatc agccaacgta gggcagggac gtggaacatt agcaactcca
     6661 gatggacgca acgcgggtac accgttagca gagggttgtt caccatcaca taatatggat
     6721 caacacggcc ctacatctgt tttaaaatct gtttcaaaat taccaacaga tgaaatcgta
     6781 ggtggggttc tcttaaatca gaaagtaaat cctcaaacgt tagccaaaga agaagataaa
     6841 ttaaaactaa ttgctttgtt acgaacattc tttaatcgtt tacatgggta ccatattcaa
     6901 tacaatgttg tttccagaga gacgttgatt gacgctcaga aacatcctga aaaacacaga
     6961 gacttaattg ttcgtgttgc aggatactct gcattcttca atgttctttc taaggcaacc
     7021 caagatgaca ttataggacg tactgagcat actttgtaaa ataaagaggt tctttttatg
     7081 gaatttatgc ttgacacatt aaatttagat gagattaaaa agtggtctga aattttgccg
     7141 ctagctgggg taacttcaaa tcccactatt gcaaaaagag agggttctat taattttttt
     7201 gaacgaatca aagatgtaag agaattgatt ggctccacac cctctattca tgttcaggtg
     7261 atttctcaag attttgaagg catcttaaag gatgctcatg aaattcgaag acaagcagga
     7321 gatgatatat ttatcaaagt acctgttact ccagctggat tacgtgcaat aaaggtgcta
     7381 aaaaaagagg gctaccatat cactgcaaca gctatttata cagttattca gggattatta
     7441 gctatcgaag taggagcgga ttacctagct ccatattata atagaatgga aaatctgaac
     7501 attgattcaa attctgtcat tcgtcaatta gctcttgcta ttgatagaca gaactctcct
     7561 agtaagattt tagctgcatc ctttaaaaat gtagcacaag taaataatgc tttagctgca
     7621 ggtgcgcatg ctgttacagc aggagcagat gtttttgaat cagctttcgc catgccatct
     7681 atccaaaagg cggttgatga tttttctgac gattggtttg ttactcaaaa tagtcgttcc
     7741 atttagatag agaggaaata catatgagaa tttttgctag tccttctaga tatattcagg
     7801 gggaaaatgc cttgtttgaa aatgccaaat caattttgga tttgggaaat tacccgattc
     7861 tattatgcga tcagttggtt tatgatattg ttggaaaacg atttgaagat tatctacata
     7921 ggtatggttt ccatattgtt ctggcgctat ttaatggtga agcttctgac aatgaaatca
     7981 atcgagttgt tgccttggct gagaaagaaa attgtgatag tattatcggt cttggtgggg
     8041 gaaagacgat tgatagcgca aaagctattg cagatttgat tgaaaagcct gttattattg
     8101 ctccaacaat tgcatcgacc gacgcacctg tatctgcttt atctgttatt tatacagatg
     8161 aaggtgcatt tgatcattat ctattttatt ctaaaaatcc agatttagtt ttggttgata
     8221 caaaagttat ttcacaagcc cctaagcgtt tattagcgtc tggtattgca gatggtttag
     8281 caacttgggt tgaggcgcgt gcggttatgc aggcaaatgg aaaaactatg ttgggacaac
     8341 agcaaacatt ggctggagtt gcaattgcga agaaatgtga agaaacgctg tttgcagatg
     8401 gtttacaggc tatggcagct tgtgaagcta aagtggtgac accagcatta gaaaacattg
     8461 ttgaagctaa tactttattg agtggtttag gttttgaaag tggaggatta gctgcggcgc
     8521 atgcaattca taatggtttt actgcattga caggtgacat tcatcattta acacatggtg
     8581 aaaaagtagc ttatggaact ttagtacaac tattattgga aaatagacct aaagaagaac
     8641 ttgataagta tattgagttt tacaaaaaaa ttggtatgcc aacaactcta aaagaaatgc
     8701 atttggatca agttggatat gatgatttaa taaaagttgg taaacaagca actatggagg
     8761 gtgagacaat tcatcagatg ccgtttaaga tttcgccttc agatgttgct caagctatta
     8821 tcgctgtaga tgcctatgta aattcaaaat aaacaataag gactactgtt ttccaaatgg
     8881 tagtctttta ttgatcctcg tattgaattc tatagcagat tgaaataaga tgagaacaaa
     8941 tcgattggga aagtaaaatt aatttctata agtgttttag caattgtttc gtactatttc
     9001 agattcagtc cactatacgt tcttcataaa tcaaaaagcg acataggttg tcggctattt
     9061 attgtgaata cattaattag cattccagtt ttatcttcgg tctaaagtaa gtattttgtg
     9121 ctatacgaga taagcgtctt gacttactcc ttgatttact gcataacaat gggataaaaa
     9181 gtgggagata gagcaattca tagtcatcaa aattaatgag atacagtata cagttttttc
     9241 tttaaacaca tttcaaattc cctcaaaaat ggtataatag taacatcaca aaattggaga
     9301 gagaccatga gtttttataa tcataaagaa attgagccta agtggcaggg ctactgggca
     9361 gaacatcata catttaagac aggaacagat gcatcaaaac ctaagtttta tgcgcttgat
     9421 atgttccctt atccgtctgg agctggtctg catgtaggac acccagaagg ttatactgca
     9481 accgatatcc tcagtcgtta caaacgtgcg caaggctaca atgtccttca cccaatgggt
     9541 tgggatgctt ttggtttacc tgcagagcaa tacgctatgg atactggtaa tgacccagca
     9601 gaatttacag cggaaaacat tgccaacttc aaacgtcaaa tcaatgcgct tggattttct
     9661 tatgactggg atcgtgaagt caacacaaca gatccaaact actacaagtg gactcaatgg
     9721 attttcacca agctttacga aaaaggcttg gcctatgaag ctgaagtgcc agtaaactgg
     9781 gttgaggaat tgggaactgc cattgccaat gaagaagtgc ttcctgacgg aacttctgag
     9841 cgtggaggct atccagttgt ccgcaaacca atgcgccaat ggatgctcaa aatcacggct
     9901 tacgcagagc gcttgctcaa tgacttagat gaactagatt ggtcagagtc tatcaaggat
     9961 atgcaacgca actggattgg taaatcaact ggtgccaatg taactttcaa agtaaaagga
    10021 acagacaagg aatttacagt ctttactact cgtccggaca cacttttcgg tgcgactttc
    10081 actgtcttgg ctcctgaaca tgaattagta gacgctatca caagttcaga gcaagcagaa
    10141 gctgtagcag actataaaca ccaagccagc cttaagtctg acttggctcg tacagacctt
    10201 gctaaggaaa aaactggtgt ttggacaggt gcctatgcca tcaaccctgt caatggtaag
    10261 gaaatgccaa tctggattgc ggactatgtt cttgctagtt atggaacagg tgcggttatg
    10321 gctgtgcctg cccacgacca acgtgactgg gaatttgcca aacaatttga ccttccaatc
    10381 gtcgaagtac ttgaaggtgg agatgtcaaa gaagctgcct acacagagga tggcctgcat
    10441 gtcaattcag acttcctaga tgaactcaac aaagaagacg ctattgccaa gattgtggct
    10501 tggttggaag aaaaaggctg tggtcaggag aaggttacct accgtctccg cgactggctc
    10561 tttagccgtc aacgttactg gggtgagcca attccaatca ttcattggga agatggaact
    10621 tcaacagctg ttcctgaaac tgaattgccg cttgtcttgc ctgtaaccaa ggatatccgt
    10681 ccttcaggta ctggtgaaag tccactagct aacttgacag attggcttga agtgactcgt
    10741 gaagatggtg tcaaaggtcg tcgtgaaacc aacactatgc cacaatgggc tggttcaagc
    10801 tggtactacc tccgctatat tgatccacac aatactgaga aattggctga tgaggacctc
    10861 ctcaaacaat ggttgccagt agatatctac gtgggtggtg cggaacatgc tgtacttcac
    10921 ttgctttacg ctcgtttctg gcacaaattc ctctatgacc tcggtgttgt tccgactaag
    10981 gaaccattcc aaaaactctt taaccaaggg atgattttgg gaacaagcta ccgtgaccac
    11041 cgtggtgctc ttgtggcaac cgacaaggtt gaaaaacgtg atggttcctt ctttcatgta
    11101 gaaacagggg aagagttgga gcaagcgcca gccaagatgt ctaaatcgct caagaacgtt
    11161 gttaacccag acgatgtggt ggaacaatac ggtgccgata cccttcgtgt ttatgaaatg
    11221 tttatgggac cactcgatgc ttcgattgct tggtcagaag aaggtttgga aggaagccgt
    11281 aagttccttg accgagttta ccgtttgatt acaagtaaag aaatccttgc ggaaaacaat
    11341 ggtgctcttg acaaggttta caacgaaaca gtcaaagctg ttactgagca aattgagtct
    11401 ctcaaattca acacagctat tgcccaactt atggtctttg tcaatgctgc taacaaggaa
    11461 gataagcttt atgttgacta tgccaaaggc tttattcaat tgattgcacc atttgcacct
    11521 cacttggcag aagaactctg gcaaacagtc gcagaaacag gtgagtcaat ctcttatgta
    11581 gcttggccaa cttgggacga aagcaaattg gttgaagatg aaattgaaat tgtcgtccaa
    11641 atcaaaggaa aagtccgtgc caaactcatg gttgctaaag atatatcacg tgaagaatta
    11701 caagaaatcg ctttagctga tgaaaaagtc aaagcagaaa ttgacggtaa ggaaatcgtg
    11761 aaagtaattg cggtaccgaa taaactcgtt aatatcgtcg ttaaataacg agtttattag
    11821 ctctatctgc caccttcaat agtccactgg actattgaag ccaactaaat tagttaacat
    11881 tgttgtgaaa taagatagga atccttcaga gtagaatctg gaggattttt tgaaccttct
    11941 tatgaaagta tgatatatag tagactgaat ctaaaatagt acgaaacaat tgctaaaaca
    12001 tttatagaaa ttaattttac tttcccaatc gatttgttct catcttattt caatacgcta
    12061 tactatgggc aactataaag tttgaaaagc gaaacaagga gaaagttata ccagtaaacg
    12121 aatatggtca gatgattggt gagtcaatgg aaggttatac accaggtgaa ctgacttcta
    12181 ttgatctctt agaagggcgt tatgctagga tagaggctct ttcagtggaa aagcatgcgg
    12241 aggatttgct agctgtttat ggtcctgata ctcctcagga gatgtggacc tacctctttc
    12301 aggagccagt agcagacatg gaggaactgg tcagcctttt aaatcagatg ttggctcgta
    12361 aggaccgttt ttactatgca atcatagaca aggcaactgg taaggctttg ggaacttttt
    12421 ctctcatgcg tattggccag taacggagta atagaagtgg gagctgttac tttttctcca
    12481 aaactcaggg ggacacggat agggacagaa gcccagtatc tactggctcg ctatgtcttt
    12541 gaagagctta actatcgtcg ttatgagtgg aaatgcgatg ctcttaacct gccatccaga
    12601 cgtactgcgg agcgtttggg ctttatttat gaaggaacct tccgtcaggc agtggtttat
    12661 aaggggcgta cgagagatac ggattggttg tctatgattg ataaggactg gcccaaagtc
    12721 aaagatcgtt tggaaacatg gttgcgtcct gaaaattttg ataaaaatgg acagcagtac
    12781 aagagcttga gagagtttta agaggtgttg acatgatcac tattagaaag caagaaatcg
    12841 tcaagttcga ggatgttttg catctctatc aggctgtcgg ttggacaaat tatataaatc
    12901 aacatcagat gctggagtag accttgtatc attcattaat aatttatctg gcacttgatg
    12961 gtgatgctgt tgtgggcttg attcgtttgg ttggagatgg tttttcatca gtttttgtac
    13021 aggatttgat tgttttgtct agctatcagc gccaagggat tggtagctcc ttgatgaaac
    13081 aggctttagg aaattttaaa gaggcctatc aagtccagct ggcgacagaa cagacagaaa
    13141 aaaacgtgga atttaatcgt tctatgggct ttgaaatttt atccacctat aattggatag
    13201 ggatgacttg gatgaatcgt aaaaaataac aaaacttgtt ttttcttaag caaaatttaa
    13261 ggatggtcta gtattatata atcattaaat aaagacctcc taactttatt taataa
//
LOCUS       DBJKQU010000049        12571 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.049, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000049 DBJKQU010000000
VERSION     DBJKQU010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12571
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.049"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..2080
                     /locus_tag="ACSUUC_001705"
     CDS             <1..2080
                     /locus_tag="ACSUUC_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HHQ8054876.1"
                     /translation="KTKANIKDTLSKLLSADAAIAENSNSIIDNYVIQKIKQNKEALL
                     LGLTYLERWYNFKYGETKAKDLVMYHLDFFGKSNSSALDNVIQLGKSGFNNLLAKNNV
                     ITYNVLLSKNYGTESLFKALEGYRKVFLPTTSNNEWFKAQTKAYIVEEKSSIPEVSKK
                     QSEQGTKYSIGIYDRLTSPSWKYQSMVLPLLTLPEEKTVFMIANISTIGFGAYDRYRS
                     KVHPKGDNLNKFVEDNVREAAKRFRDHYDYWYKILEPENREKLYRSLLVYDAFKFGRD
                     NTEDKVTYQADFETDHPAIKYFFGPAGNNVVHNGHGAYATGDAFYYMAYRMLDKDGAV
                     TYTHEMTHNSDREIYLGGYGRRSGLGPEFYAKGLLQAPDHPYDPTITINSVLKYDDSE
                     NSTRLQVADPTQRFNSAEDLHNYMHNMFDLIYTLEILEGRAVAKLDYNAKNDLLRKIE
                     NKYKQDPDGNSVYATNVVRRLTMDEVNKLNSFDSLIENDIITSRGYKDQEYKRNGYYT
                     IDLFSPIYSALSGEKGTPGDLMGRRIAFELLAAKGYKEGMVPYISNQYEKDAKAAGSK
                     IKSYGKEVGLVTDKLVLEKVFNNRYSSWVEFKKAMYNERIAKFNNLISVSFNNPNVSW
                     GRTNRITITSIANLQNMINTAVNEDAEDFRAQLYPDTNSRVLKLKKAIYKAYLDQTND
                     FRRSIFENKK"
     gene            2124..7361
                     /gene="zmpD"
                     /locus_tag="ACSUUC_001706"
     CDS             2124..7361
                     /gene="zmpD"
                     /locus_tag="ACSUUC_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease ZmpD"
                     /protein_id="HHQ8054877.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSIFLGSFLFALSVVGVSTYHYLDYS
                     TLTQTERDQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTVLGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDR
                     TVSSVSPASTVSPVEQPKVVTDKGEPEVQPALPEAVVTEKGEPEVQPALPEAVVTEKG
                     EPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEP
                     ISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDNSVKQVSEDGERQIVT
                     SYEELHGKKISESVETVTILKEMKPEIIVKGTKEKTAPVLTLTKVTEDAMNRSANLNY
                     ELDNKDNAEISSIVAEIKDGDTVVKRVDLSKEKLTDAVQNLDWFKDYKIATTMIYDRG
                     QGSETSKLDERPLRLELKKVEIKNIASTNLVKVNDDGTETPSDFMNEKPSEEDVKKMY
                     LKITSRDNKVTRLTVDSIEEVTEEGQKLYKITAEAQDLIQHTDPTKVRNKYVYYIEKP
                     HPKEDNVYYNFKDLVDAMNTDKNGTFKLGADLNATGVPTPKKWYVDGDFRGTLKSVEG
                     KHYTIHNTERPLFQNIIGGTVTKVNLGNVNINMPWADRIAPIADTIKGGAKIEDVKVT
                     GNVLGRNWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVERAYV
                     DANLIGKKAKAAGIAYWTQNSGDNHKVGVEGAVKKGIVKGTIQVESPVEVGGAVGRLS
                     HHGYIGEVVSMMKVKKGEIFYGSSDMNDDPYWVANNVRGNYVVNGVSEGTISYARAKE
                     HHRIKPISQSEADTKIMMLGITAQDFAINEPVVNRLNRLTRKEDEYKSTQDYKVDRDL
                     AYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMV
                     HYADGTKEEMDVTKNADSKVKQVREYTIAGQNVVYTPNMVEKDRNQLIQDIKDKLASV
                     QLISPEVRALMDARKKPEENTDERKNGYIKDLYLEESFAETKANLDKLVKSLVENADH
                     QLNSDETAMKALVKKVDENKAKIMMALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSV
                     DLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDW
                     FIHAAKNVYVSEPQTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAHMFLISTYN
                     TMAYSSFEKYGKYTEEARNEFKKEIDKVAHAQQTYLDFWSRLALPSVRDQLLKSENRV
                     PTPVWDNQNYSGIKGINRMGYDEKKVPIAPIRELYGPTWKFHNTNWNMGAMASIFPNP
                     NNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTP
                     SSIGHQGEYGALGLNMAYHRENDGDQWYNYDPDKLQTREDIDRYMKNYNEALMMLDHV
                     EADAVLPQLNGDNSKWFKKIDREMRRNLGDGLNNLVAPHQWDNVRDLNQEESSKKLSS
                     INDLIDNNFMTKHGNPGNGRYRPEDFRPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKH
                     NAFRMWGYYGYDKGFTSYVSSKYQGEADKQNQGRLGDDFIIKKVSNNQFSNLEDWKKY
                     WYHDVKSRAEKGFTEITIDGQTIHNYNELKDLFDKAVTEDLKKAGNYSNTENLKSKVF
                     KALLKNTDGFFNPLFKKDI"
     gene            7528..8874
                     /locus_tag="ACSUUC_001707"
     CDS             7528..8874
                     /locus_tag="ACSUUC_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HHQ8054878.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFRLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSCLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKMDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            9289..10140
                     /gene="ylqF"
                     /locus_tag="ACSUUC_001708"
     CDS             9289..10140
                     /gene="ylqF"
                     /locus_tag="ACSUUC_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HHQ8054879.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEPSVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            10127..10906
                     /locus_tag="ACSUUC_001709"
     CDS             10127..10906
                     /locus_tag="ACSUUC_001709"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HHQ8054880.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            10922..12472
                     /locus_tag="ACSUUC_001710"
     CDS             10922..12472
                     /locus_tag="ACSUUC_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HHQ8054881.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHMIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGVICVNLRLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         4246 a         2128 c         2536 g         3661 t
ORIGIN      
        1 taaaacaaaa gcaaatataa aagatacttt atcaaaactt ctgtcagcgg atgcagcaat
       61 cgctgagaat agtaattcga taattgataa ttatgttatt cagaaaatca aacagaataa
      121 agaagcttta ttgttaggat taacatactt agagcgttgg tacaatttta aatatggtga
      181 aacgaaagca aaagatttag ttatgtatca cttggatttc ttcggtaaat ctaatagttc
      241 tgcattagat aatgttattc aattaggtaa atctggattt aacaatttac tagcaaaaaa
      301 taatgtaatt acttacaatg tattattatc taaaaattat ggaactgaaa gtttatttaa
      361 agcattagaa ggatatagaa aagtattctt accaacaact tctaacaatg agtggtttaa
      421 agctcaaact aaagcatata ttgttgaaga aaaatcttct attccagaag taagtaaaaa
      481 acaatcagaa caaggaacta agtattctat aggaatttat gatagattaa ctagtccgtc
      541 atggaaatat caaagtatgg tcttaccact attaacttta cctgaagaaa aaacagtatt
      601 tatgatagcg aatatttcaa caataggatt tggtgcttat gatagatata gaagtaaagt
      661 ccatcctaaa ggagataact taaataaatt tgtagaagac aatgtaagag aagctgcaaa
      721 aagatttaga gatcattatg attattggta taaaatatta gagcctgaga atagagagaa
      781 actttataga agtttattag tatacgatgc atttaaattt ggtcgagata atactgaaga
      841 taaagtaact tatcaagctg attttgaaac tgatcatcca gctataaaat acttctttgg
      901 acctgcgggg aataatgttg ttcataatgg acacggagca tatgctaccg gagatgcatt
      961 ctattatatg gcatatcgta tgttggataa agatggagct gtaacatata ctcatgaaat
     1021 gacacataac tctgatagag aaatttatct tggaggatat ggaagaagaa gcggattagg
     1081 gcctgagttt tatgctaagg gcttattaca agcacctgac cacccatatg atccaacaat
     1141 aacaattaac tctgtgttga aatatgatga ttcagaaaat tcaacaagac ttcaagtagc
     1201 tgatccaact caacgattta atagtgcaga agacctacat aattatatgc ataatatgtt
     1261 tgatttaata tatactcttg aaatattaga aggtcgtgct gtagctaaat tagattataa
     1321 tgcgaaaaat gatttattaa gaaaaattga gaataaatat aagcaagatc cagatggtaa
     1381 ttctgtttat gcgacaaatg ttgttcgcag attaacgatg gatgaagtta ataaattaaa
     1441 ttcttttgat agtttaattg aaaatgatat tattactagc agagggtaca aagaccaaga
     1501 atataagaga aatggttatt atacaattga tttattttca ccgatttatt cagctcttag
     1561 tggagagaaa gggactcctg gtgatttaat gggacgtcgt atagcattcg aattattagc
     1621 tgcaaaagga tataaagagg gcatggtacc ttatatctca aatcaatatg aaaaagatgc
     1681 aaaagctgcg ggaagtaaga ttaaatctta tggtaaagaa gtaggtttag ttacagataa
     1741 attagtactt gaaaaggtat ttaataatcg ttactcatct tgggtagaat ttaaaaaagc
     1801 aatgtataat gagcgaatag ctaaatttaa taatctaata agtgttagct ttaataatcc
     1861 aaatgtaagt tggggaagaa ctaatagaat aacaataact agcatagcca accttcaaaa
     1921 tatgataaat acggctgtca atgaagatgc tgaagatttt agagcacaat tataccctga
     1981 tacaaatagt agagttctta aactgaaaaa agcaatatat aaagcctatc ttgaccaaac
     2041 aaatgatttt agaagatcaa tttttgagaa taaaaaatag tgtttactat taggaaataa
     2101 aaagtgaatg tggaggatta gaattgtcat tattaaaaaa agataaattt tccattagga
     2161 aaataaaggg tattgttggt tcgatattct tggggagttt tttatttgca ctgtcagttg
     2221 ttggtgtatc gacttatcat tacttagatt atagtacttt gacacaaact gaacgtgatc
     2281 aactcaaaca aggtagacct gatgaatcaa aagagtcata tgctttggtt tatgaaaaag
     2341 acgcattacc aaacacagga agttctcaat ctattatgac tgtattgggt ttgttagcta
     2401 tcgggagtct tattgtgatt atcacaaaag ataaaaagag gaaaaaaata gctacatttt
     2461 tgattgtagg ggcgacaggt ttagttacac tatcaactgc ttcagcactt aatttgaatg
     2521 ctaacatcca tgagtctgga cgtgatggtg tgttgcaaat ttctggttac agatatgttg
     2581 gttacttgga gcttgatgat agaactgttt cgtcggtttc tccagcatca actgtttctc
     2641 cagttgagca acccaaagtt gtgaccgaca aaggcgaacc agaagttcag ccagcgttac
     2701 cagaagcagt tgtaactgaa aaaggggaac cagaagtaca accagcctta cccgaagcag
     2761 ttgtaactga aaaaggggaa ccagaagttc atgagaagcc tgactatacg caaccaatag
     2821 gtgcaaacct tgttgagcct gaagttcatg agaaactagc atacactgaa cctgtaggta
     2881 caacaggagt agatgaaaat ggaaacttga ttgagccacc tgttaacgat attccagagt
     2941 atactgaacc aatatctaca gtttcagaag ttgcatcaga aagagaagag ttgccttctt
     3001 tacataccga tattcgtaca gagactattc ctaaaaccac tatagaagaa tctgatccta
     3061 gcaaatttat aggcgataat tctgttaaac aagttagtga ggatggcgaa cgtcaaattg
     3121 ttactagcta tgaagagtta catggcaaaa aaatcagcga gtcagttgaa acagtaacaa
     3181 ttttgaaaga aatgaagcct gaaattattg taaaaggtac aaaagaaaaa acggctcctg
     3241 ttttaacctt gaccaaagta acagaagatg ctatgaatcg ttctgccaac ttaaattatg
     3301 agcttgataa taaagataat gctgaaatat caagtattgt agctgaaatt aaagatggtg
     3361 atacagtagt taaaagggtt gatttatcta aagaaaaatt aactgacgct gtacaaaatt
     3421 tggattggtt taaagattat aagattgcaa caacaatgat ttatgatcgt ggtcaaggtt
     3481 ctgaaacgtc taaactggat gaaagacctc tgcgtttgga gttgaaaaag gtcgaaatta
     3541 aaaatatcgc atctactaat ttagtgaagg taaatgatga tggtactgaa acacctagtg
     3601 attttatgaa tgaaaaacct tcagaagaag atgttaaaaa aatgtactta aaaatcacta
     3661 gtcgcgataa taaggtaact cgtttaactg tagactctat tgaagaagtg actgaagaag
     3721 gtcaaaaact ttacaaaata actgctgaag cacaagattt gattcaacac acagacccaa
     3781 cgaaggttcg taataagtat gtttattata tagaaaaacc ccatcctaaa gaagataatg
     3841 tctactataa ctttaaagat ttagtagatg ctatgaatac tgataaaaat ggtacattta
     3901 aacttggtgc agatttgaat gccactggtg ttccaacacc taagaaatgg tatgttgacg
     3961 gcgactttag aggtacattg aagagtgtag aggggaaaca ttatactatc cacaacacgg
     4021 agcgtccgtt attccagaat attattggtg gtacagtaac caaagtaaat ctgggaaatg
     4081 taaatatcaa tatgccatgg gcagaccgca tcgcaccgat tgctgacact attaaaggtg
     4141 gcgctaaaat tgaagatgtc aaagtgactg gtaacgtatt aggtagaaac tgggtatctg
     4201 gatttattga taagattgac aaccaaggta cactcagaaa tgtagccttt atcggaaatg
     4261 tgacatctgt aggtgatggt ggtcaattct tgaccggtat cgttggtgag aactggaaag
     4321 gactagtcga acgtgcgtat gttgacgcaa atcttattgg caagaaagcc aaggctgctg
     4381 gtattgctta ttggacacaa aacagtggtg acaatcataa agttggtgtc gaaggtgcag
     4441 tcaagaaagg aattgtgaag ggtaccattc aggtagaaag tcctgttgaa gtcggcggtg
     4501 ctgttggacg tttgagtcat catggttata tcggggaagt cgtatctatg atgaaagtta
     4561 agaagggtga aattttttat ggttctagtg atatgaatga tgacccatat tgggtggcga
     4621 ataatgtacg aggaaattat gtcgttaatg gtgtgagtga aggtacgata tcttatgctc
     4681 gtgctaaaga acaccatcgt atcaaaccaa tttcacagtc agaagcagat actaaaatta
     4741 tgatgttagg tattacagca caagattttg ctatcaacga acctgtggtc aatcgcttaa
     4801 accgtttaac cagaaaagaa gatgaatata agtcaaccca agactataaa gtagatcgag
     4861 atctggctta tcgtaatatt gagaaacttc aaccatttta taacaaagaa tggattgtca
     4921 accaaggtaa caaacttgca gaagattcaa acttagctaa gaaagaagtc ctttctgtta
     4981 cgggtatgaa ggatggacag tttgtaactg acttatcaga tattgataag attatggttc
     5041 actatgctga tggtactaaa gaagaaatgg acgtcactaa gaatgctgat tctaaagtga
     5101 aacaagttcg tgaatatacc atcgctggac aaaacgttgt ttatacacca aatatggttg
     5161 agaaagaccg taaccaattg attcaagata tcaaagataa gttggcgtca gttcaattga
     5221 tttctcctga agtacgtgct ttgatggatg cacgtaagaa accagaagaa aatactgatg
     5281 aacgtaagaa tggttatatt aaagaccttt acttagaaga aagctttgct gaaacgaaag
     5341 ctaatcttga taaattggtt aaatccttag ttgaaaatgc agatcatcaa ttaaatagtg
     5401 acgaaacggc tatgaaagca cttgttaaga aggtggatga aaataaagct aaaatcatga
     5461 tggctctgac ttatctcaat cgttactatg atatcaagta tggggatatg actatcaaga
     5521 acttgatgat gtttaaacct gatttctatg gtaaatcagt tgaccttctt gatttcttga
     5581 ttcgaattgg atcaagtgag agaaatatca aaggtgacag aactttggat gcttatcgtg
     5641 atatgattgg tggaactatt ggtaagtctg aattacatgg attcttagat tacaatatgc
     5701 gtctcttcac taacgatact gatttaaatg attggttcat ccatgcagct aagaatgtat
     5761 atgtatcaga acctcaaaca acgaacccag attttgttaa taaacgacat cgtgcatttg
     5821 atggtttgaa caacggtgtt cataatcgta tgattctacc tctattaact cttaagaatg
     5881 cacatatgtt cttgatttca acttacaata caatggctta tagttctttt gagaaatatg
     5941 gtaagtatac agaagaagct agaaatgaat tcaaaaaaga aattgataag gttgcacatg
     6001 ctcaacaaac atacttagac ttctggtcac gtttagcatt gccaagcgta cgtgaccaat
     6061 tactcaagag tgagaatagg gtaccaactc ctgtgtggga taaccaaaac tatagtggta
     6121 ttaaaggaat aaaccgtatg ggttatgatg agaagaaagt accaattgcg ccaattcgtg
     6181 agttatatgg tccaacttgg aaattccata ataccaactg gaatatggga gctatggcat
     6241 ctattttccc aaatcctaat aacaatgacc aagtttattt catgggaaca aatatgatta
     6301 gtccgtttgg tatttcagcc tttactcatg aaactacaca cgttaatgat agaatgcttt
     6361 acttcggtgg tcatagacac cgtcaaggta cagacgtcga agcctatgct caaggtatgc
     6421 tacaaactcc gtcaagtatt ggtcaccaag gtgaatatgg tgctttaggt ttgaacatgg
     6481 cttatcatcg tgaaaatgat ggtgaccaat ggtataacta tgaccctgat aagcttcaaa
     6541 ctcgtgaaga tatcgatcga tatatgaaaa actataatga agcactgatg atgctagatc
     6601 atgtagaagc agacgccgta cttccacaat tgaatggtga taatagcaag tggttcaaga
     6661 aaattgatag agaaatgcgc agaaatcttg gggatggttt gaataactta gtagcaccgc
     6721 accaatggga caacgttcgt gacttaaatc aagaagagag ttctaagaaa ttatcaagta
     6781 ttaacgattt gattgataat aatttcatga ccaaacacgg aaatccaggt aacggacgtt
     6841 atagaccaga ggattttaga ccaaactcag cttacgtaaa tgtcaatatg atggcaggaa
     6901 tttacggtgg gaatacgagt caaggtgctc ctggttcatt atcgttcaaa cataatgcct
     6961 tccgtatgtg gggttattat ggatatgaca aaggtttcac tagttatgta tctagcaaat
     7021 atcaaggtga agctgataaa caaaaccagg gtagattagg tgatgatttc attatcaaaa
     7081 aagtttcaaa caaccaattc tcaaatcttg aagattggaa gaaatattgg tatcatgatg
     7141 tgaaatccag agctgaaaaa ggattcacag agattacaat tgatggacaa accattcaca
     7201 actataatga actgaaagac ttattcgaca aagctgtcac agaagacctc aagaaagctg
     7261 gaaactactc aaatactgag aatttgaaat ccaaagtctt caaagctctt cttaaaaaca
     7321 cagacggttt ctttaatcca ttgttcaaaa aagacattta aaccccaatt attcacccca
     7381 aatctaaaaa ccatccagaa tccttgcctt agcttagatc ctggatggtt tctttttcac
     7441 ccaatgggtg ttttttacta gacaaaaaag agtttcccct ttatggtata agtgtagaaa
     7501 aaaaacacaa aaagaaagga aactcacatg aacagtttac caaatcatca cttccaaaac
     7561 aagtcttttt accaactatc tttcgatgga ggtcatttaa cccagtatgg tggtcttatc
     7621 ttttttcagg aacttttttc ccagttgaaa ctaaaagagc ggatttctaa gtatttagta
     7681 acgaatgacc aacgccgcta ctgtcgttat tcggattcag atatccttgt ccagttcctc
     7741 tttcgactgt taacaggcta tggaacggac tatgcttgta aagaattgtc agctgatgcc
     7801 tactttccaa aattgttgga aggagggcag cttgcttcac agccaacctt atcccgtttt
     7861 ctttccagaa ctgacgagga aacagtccat agtttgcgat gcctcaacct tgaattggtc
     7921 gaattctttt tacagtttca ccagctaaac caactcattg tagatatcga ttctacccat
     7981 ttcacaactt atggcaagca agaaggtgtt gcttataacg cccactatcg tgctcatggc
     8041 tatcatcctc tttacgcttt cgaggggaag acaggttatt gtttcaatgc ccagcttcgt
     8101 cctggtaatc gttattgttc tgaagaggca gacagcttta tcacacctgt tttagaacgg
     8161 tttaatcaac ttctctttcg aatggatagt ggctttgcga ccccaaaatt atacgattta
     8221 attgaaaaaa cagggcaata ctacctcata aaactcaaga aaaatactgt tctgagctgt
     8281 cttggagacc tttccctccc ttgcccacag gatgaggact taaccatctt gccccactcc
     8341 gcctactcag aaactctcta tcaagcagga tcttggtcgc acaagcgtcg tgtctgccag
     8401 ttctctgaac gaaaagaagg aaacttgttc tacgatgtta tttctctcgt tacaaatatg
     8461 acgagtggaa caagccaaga ccagtttcag ctttatcgtg gacgtggtca agccgagaat
     8521 ttcatcaagg agatgaagga gggatttttt ggcgataaaa tggatagttc aaccttaatc
     8581 aaaaacgaag ttcgtatgat gatgagctgt atcgcctaca atctctatct ttttctcaaa
     8641 catctagctg gaggtgactt ccaaacttta acaatcaaac gcttccgcca tctttttctt
     8701 cacgtggtag gaaaatgtgt tcgaacagga cgcaagcagc tcctcaaatt gtctagtctc
     8761 tatgcctatt ccgaattgtt ttcagcactt tattctagga ttagaaaagt caacctgaat
     8821 cttcctgttc cttatgaacc acctagaaga aaagcgtcgt taatgatgca ttaaagaaca
     8881 gtcgagatga aaaaatcgtg tgacgcacca agggaggagt ctgccctttt gaggaaatct
     8941 agcgaggaaa aacgatactg gaacagcaga aagtaaaact gacctcatta ggacatgagg
     9001 tcaggggttt tgtaagttac atctagttga gagaggtatg aatgatttgg gttaaatgtt
     9061 taaaacataa agaggacagt tttttgctcc ctctgaaaag tcatcatttg atggcttttt
     9121 tctatatagg gtaaaaggct atcatcggac aaaataaaga aggcatgata taatataaag
     9181 tagattttta tgtcataaaa caagaactgt ttggacatca ttcattttta gattgagatc
     9241 tcttagttct agattaacag cttcagagct acgaaaggaa aaaactcaat ggctactatt
     9301 caatggtttc ctggtcacat gtctaaagct cgtcgacagg tgcaggagaa tttaaaattt
     9361 gttgattttg tgacgatttt agtagatgca cgcttgcctc tatctagtca aaatcctatg
     9421 ttgaccaaga ttgttggtga taaaccaaaa ctcttgattt taaacaaggc cgacttggct
     9481 gatccagcaa tgaccaagga atggcgtcag tattttgaat cacaaggaat ccagacgcta
     9541 gctatcaact ccaaagagca agtgactgta aaagttgtaa cagatgcggc caagaagctc
     9601 atggctgata agattgctcg ccagaaagaa cgtgggattc agattgaaac cttgcgtacc
     9661 atgattatcg ggattccaaa cgctggtaaa tcaactctga tgaaccgttt ggctggtaaa
     9721 aagattgctg ttgttggaaa caagccaggg gtcacaaaag gtcaacaatg gcttaaaacc
     9781 aataaagacc tggaaatctt ggatacaccg gggattctct ggcctaagtt tgaggatgaa
     9841 actgttgcac ttaagttggc attgactgga gctatcaaag accagttgct tcctatggat
     9901 gaggttacca tttttggtat caattatttc aaagaacatt atccagaaaa gctggctgaa
     9961 cgcttcaaac aaatgaaaat tgaagaagaa ccgtctgtga ttattatgga tatgacccgc
    10021 gccctcggtt tccgtgatga ctatgaccgt ttttacagtc tcttcgtgaa ggaagtccgt
    10081 gatggcaaac tcggtaacta taccttagat acattggaag acctcgatgg caacgattaa
    10141 agaaatcaaa gaactccttg tgacagtcaa ggagttagaa agccctattt ttttagagct
    10201 tgaaaaggat aatcgctcag gagttcaaaa ggaaatcagc aagcgtaaaa gagccatcca
    10261 agctgaatta gatgaaaatt tgcgcttgga atccatgctt tcttatgaaa aagaacttta
    10321 taagcaagga ttgaccttaa ttgcaggtat tgatgaggtt ggtcgtggtc ctcttgctgg
    10381 tcctgtagtc gctgcggccg ttattttacc taaaaattgt aagattaaag gtctcaacga
    10441 cagcaagaaa attcctaaaa agaaacatct ggagattttc caagccgttc aagaccaagc
    10501 cttgtcgatt ggaattggta tcatagataa tcaggtcatc gaccaagtca acatctatga
    10561 agcaaccaaa ctagccatgc aagaagcaat ctcccagctc agccctcaac cagagcacct
    10621 tttgattgat gccatgaaac tggacttgcc catttcacaa acctccatta tcaaaggaga
    10681 tgccaactcc ctctctatcg cagcagcatc tatagtagcc aaggtaacac gtgatgaatt
    10741 gatgaaagaa tacgatcagc agttccctgg ctatgatttc gctactaatg caggatatgg
    10801 cacagctaaa catctggaag gcctcacaaa actaggagtt accccaattc accgaaccag
    10861 ctttgaaccc gttaaatcac tggttttagg taaaaaagaa agttaattga aaggaaatac
    10921 catggaggaa cagtcggaaa tagtccgttc taagaaagaa ttcgcctttg catccagcac
    10981 tatactatcc caagttggtc gaggaatcat tgtcggcctc atcgttggaa ttatcgtcgg
    11041 atcctttcgt ttcttaattg aaaagggctt ccacatgata caaggagttt atcaagatca
    11101 agggtactta gtgcgcaatc tttttgtact ggttttgttt tatatactca tctgttggct
    11161 cagtgccaaa ctaacacggt cagaaaaaga tattaaaggc tcaggaattc ctcaagtcga
    11221 agccgaactg aaaggcctca tgtccctcaa ctggtggggc attctttgga aaaaatatgt
    11281 gctaggtatt ctcgctattg ccagtggact catgctgggt cgagagggac ccagtattca
    11341 acttggagca gttggtggta aaggaattgc caagtggctc aaatccagtc cagtagagga
    11401 acgttccttg attgccagtg gagctgcagc aggtttagcc gcagccttta atgctcctat
    11461 tgcagcactt ctctttgttg tagaagaagt ctatcaccat ttttcgcgct ttttctgggt
    11521 ctcaactcta gcagccagca tcgtagcaaa ctttgtgtct ctactcatgt tcggtttgac
    11581 accagtattg gatatgccag ataacattcc tcccatgacc ctagatcagt attggatata
    11641 tctcgtcatg ggaattttcc ttggattttc aggctttctc tatgagaaag ctgtattaaa
    11701 cgttggaaga gtttatgact tgattggtca aaaaatccat ttggatagag cttattatcc
    11761 catcttggct tttatcctta tcataccagt cggaatcttc ttacctcaaa tcattggtgg
    11821 cggaaatcag cttgtccttt ctttaactga acaaaatttt agtttccaag ttttattagc
    11881 ttactttttg atccgcttta tttggagtat gattagctat ggaagtggac tgccaggagg
    11941 aattttcctc cccattttag ctcttggttc tttgcttggt gccttaattg gtgttatctg
    12001 tgtcaatctt agacttgtca gtcaagagca attccctata tttgtcattc taggaatgag
    12061 tggctatttt ggagccatat caaaagctcc cttaaccgct atgatcctcg taactgagat
    12121 ggtaggagat attcgcaacc tcatgccact tggtcttgtc actcttgttt cttatattat
    12181 catggatttg ctcaaaggta cgccagtcta tgaagccatg ctggaaaaaa tgcttccaga
    12241 agaagtatct agcgaaggag aagttacact tatcgaaata ccagtttctg ataaaattgc
    12301 tgggaaacaa gttcatgaac tcaacttacc acacaacgtc ctcatcacaa ctcaagtcca
    12361 taatggcaag agccaaacag ttaacggctc aaccagaatg tatctgggtg atatgattca
    12421 cctggttatt ccaaaaagtg aaattggaaa agtcaaagat ttgttgttgt agtacaatca
    12481 tttacataat ttatattatg taaatgattg gcttgattta tttagaaaac cgattctcag
    12541 aaatgagatc ggttattttt tactgatgag g
//
LOCUS       DBJKQU010000050        12436 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.050, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000050 DBJKQU010000000
VERSION     DBJKQU010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12436
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.050"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            212..385
                     /locus_tag="ACSUUC_001711"
     CDS             212..385
                     /locus_tag="ACSUUC_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054882.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            571..1098
                     /locus_tag="ACSUUC_001712"
     CDS             571..1098
                     /locus_tag="ACSUUC_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HHQ8054883.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            1225..1953
                     /locus_tag="ACSUUC_001713"
     CDS             1225..1953
                     /locus_tag="ACSUUC_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HHQ8054884.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKS
                     TPIFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWY
                     EEDKDKLRQKGLNKKMNYDVGESL"
     gene            2637..2798
                     /locus_tag="ACSUUC_001714"
     CDS             2637..2798
                     /locus_tag="ACSUUC_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054885.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            2890..4569
                     /locus_tag="ACSUUC_001715"
     CDS             2890..4569
                     /locus_tag="ACSUUC_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHQ8054886.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGYKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            4837..5403
                     /locus_tag="ACSUUC_001716"
     CDS             4837..5403
                     /locus_tag="ACSUUC_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054887.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            5724..5912
                     /locus_tag="ACSUUC_001717"
     CDS             5724..5912
                     /locus_tag="ACSUUC_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HHQ8054888.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            5974..6732
                     /locus_tag="ACSUUC_001718"
     CDS             5974..6732
                     /locus_tag="ACSUUC_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HHQ8054889.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            6790..7644
                     /locus_tag="ACSUUC_001719"
     CDS             6790..7644
                     /locus_tag="ACSUUC_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HHQ8054890.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            7756..8640
                     /locus_tag="ACSUUC_001720"
     CDS             7756..8640
                     /locus_tag="ACSUUC_001720"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001727 - lipid kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol/lipid kinase family protein"
                     /protein_id="HHQ8054891.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            8803..9882
                     /locus_tag="ACSUUC_001721"
                     /pseudo
     CDS             8803..9882
                     /locus_tag="ACSUUC_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            9876..11212
                     /locus_tag="ACSUUC_001722"
                     /pseudo
     CDS             9876..11212
                     /locus_tag="ACSUUC_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
     gene            complement(11253..12104)
                     /locus_tag="ACSUUC_001723"
     CDS             complement(11253..12104)
                     /locus_tag="ACSUUC_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HHQ8054892.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTKTESFANLIQYIRKQYSLQNINNIQSLLSDS
                     SNYTLDSFEKTMVKSILHTMDSRIIPSDDELLQLADYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKRIVTQLAINCFILSIDKEEFSNCSYLINEIK
                     GLLENELNFYEQTVFLYATGYYEFKRQLSSGIETMKQAIQVLDILGEDKLKLHYTSHF
                     DKLVNNK"
     gene            12186..12257
                     /locus_tag="ACSUUC_001724"
     CDS             12186..12257
                     /locus_tag="ACSUUC_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HHQ8054893.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
BASE COUNT         4749 a         1693 c         2425 g         3569 t
ORIGIN      
        1 atagaaatag ataagctaat aaaacaggga gaaaaaccaa gtgtaatagc acagattaaa
       61 aagttccaag accaagtcaa taaagataat gaatacagag aaatgatgaa aaacaagaaa
      121 atggatcaag aaagataaga cctggtaaaa atatcttatc caagctataa tatgaccaaa
      181 caactaaagt cagatctagg aggtaataga gatgaataaa aggcaagagc taatagatga
      241 actcataaaa gcaaatgaag atggaacata caaaacctat aaaagcacag aagaaataaa
      301 agcaatgaac aatgaagaaa tacagattat atattctaac atgaaaaact atctatcaga
      361 caaaagaaca cacataaact attaaaggtg gaaaggtagt gtaagctatt tttaaaagta
      421 taaaaggtac aaagacctaa gaaatatata aaaacatcaa aataaagtat tccaccacca
      481 agaacaataa aataaaaaca agcaaaggga agtatagaaa aattaaaacc tatacttccc
      541 ttttttaatt caaacaaagg agagaaaagc atgataaacg aagaaataag caaggaagca
      601 ggtcaagcag cacaaaccat aatatcatac acaataaagg caacaaaaga atcaatcaat
      661 ttagaaaaag aaataagaaa aaagatgaat gaaactttag aaaaagcaaa tggaaactta
      721 aaaagtctta tgggcgatga aatgaaaata aaagacctct acaagaaagg acaactagaa
      781 aatataagca tagatcaaat cgacctcaaa gacttaaaaa aagaactaaa caaacttgga
      841 gtaagtttct cagtaatgaa aaacaaagaa agcaaaaact atgaaatatt cttccaagcc
      901 aaagacataa aagtaatgga atatgccttt aagcaagtca tagccaagga aaataaaaaa
      961 gaaaaagaaa gtatcctaaa acaaataaag aaatacaaag acctatccaa aaacaaagat
     1021 aagacaaaag aaaaaggaaa aaggaaagta aaagaaaaag taaaaccaaa caaaaaagat
     1081 atgaccagag aaatctaaag ggagtaacga aaagttacac ccttaaataa ccataataac
     1141 aagacttccg aaaaacagaa gtccagaatt ccgaaaatcg gaaatcaaga atttcgatta
     1201 tcgaaaatca agaaaggagc agatatggca acaaacaaaa gatactattg gataaaatta
     1261 aaagaagaat ttttcacaga caaaaggata aaaaggttaa ggagaatatc tggaggagat
     1321 acctatacga taatctacct aaaacttcta ctactaagcc taaaagatga gggcaaactc
     1381 tattatgacg gagtagaaag tgattttata aaagagttag cactaaccat agatgaaaca
     1441 gacgatgatg taatggtaac agtaaattat ttaatcaatc aaggcttatt agaagttgta
     1501 acagaaaatg atgaatacta cctaactgaa ataccaaact taatcggatc agaaacagcc
     1561 tgggcagaga aaaaaagaag atacagacaa aataaacaga ggacattgtc cttaatgagt
     1621 ccaacccatg tccgacaaga gatagagata gagaaagata tagagataga taaagagaga
     1681 gagggagaga tagataaaaa gtccaccccc attttttatg gagaattcaa aaatgtaagg
     1741 ttaagcaaag aagaatataa aaatctaaaa gaaaaattaa actcacacac agatataatg
     1801 ataaataaac tatccagata catggaaagc agtggtaaga cctatcaaaa ccactatgtg
     1861 acaatcttaa aatggtatga agaagataaa gacaaactaa gacagaaagg tttaaataaa
     1921 aaaatgaatt atgatgtagg agaatcttta tagataaaaa gaggtggaaa ggcactatta
     1981 aagactttaa gtttaaaaag gtatcaaagt atgccagaga taaaaaaata taaatatgac
     2041 actttaaagg cgattagaaa attaaagaaa tgctagaaga cttttagatg acagttacca
     2101 agagggtcta attttcactg ctacttatgc agtaggaatt ggaccttttt atataagcaa
     2161 attctatttc aaaattggtt accaagaaag acttcttttc actgttaagt ataagagggt
     2221 aatttataga attttgttac atcaagataa atattttctg atggtcaaat tttaaaaaga
     2281 ttaataactc tcgataaatt ttgaacctta acaattgaat agaccaagac aagacgttaa
     2341 ttatttttgg agcgtaataa cctatccgtc aagatctttc ggctgaataa ttcggcaaaa
     2401 aaagttctgc taagcaaaaa gaaagtgagc gataagtaag agtttgaata tagggaggga
     2461 taccctatcc gctatgaaga aaatgaggat aatgatactt ctaaggttga agcaggctca
     2521 tccggaatag aggcggaggt gagattccta tgttgctaat ccaaagcact tgtcaatgtc
     2581 aaaaaactta attaaacaaa taattattag atataaaact ttagaggagg tatatattgg
     2641 acaatgactg gaatggattg gctgatttaa tagcaaatct gattgcaaaa tatgctggtg
     2701 ctttagattt agataatcta cccgatccaa cgccagcaaa aaatcaagag atgaaaaata
     2761 gttttgacat ggcaaaaaca caaattgaga cggactaata aaagtgttat aatatacttg
     2821 aaatgatagt ccaaacttaa attaaaaaaa ttatatatga tatagaaaaa ttatattgag
     2881 gttaatacta tgtcaaaaga aaaaataaaa gtatacctct atacacgagt atctacgtca
     2941 atacagatag aggggtattc gttagaggca caaaaatcac gaatgaaagc ttttgctatt
     3001 tacaatgatt atgaaattgt tggagaatat gaagatgccg ggaagtctgg caagtctatt
     3061 gaaggtagaa tacagttcaa tcgaatgatg gaagatataa aatctggaaa agatggagta
     3121 tcttttgttc ttgtgtttaa gttatcaaga tttgcaagaa atgccgctga tgttctttct
     3181 acacttcaga taatgcagga ttatggagtt aatcttatct gcgttgaaga tggcattgat
     3241 tcatctaaag atgctgggaa actaatgatt tctgttttat cagctgtggc tgaaatagaa
     3301 agagaaaaca tccgtattca aacaatggaa ggtcgcattc aaaaagcaag ggaaggaaaa
     3361 tggaatggtg gctttgctcc gtatggatat aaacttgaag acggcaagct gtttataaat
     3421 gaggaagagg cagttgcaat aagaacgatt ttcgaccagt atgtaaatac tacgatagga
     3481 gccaatggga tatctaaata cttagagaat catggaatta gaaaaatccc aagacagaat
     3541 ggtaagaatc ctttgtttga tgcaggtctt ataagaaaga tattaaagaa tcctgtatat
     3601 aatgggaaaa tagcatttgg aagaagaact ttagaaaaag ttcatggtac aagaaatgaa
     3661 tataagcagg ttgaacaaga tgaatatcta atatctgaag ggatacatga agctatagtt
     3721 tccgatgaag tttggcaagc tgctcaggtt aagctaaaat ctcaagcaaa gaaatatgag
     3781 catgtgaata aaggaaaaga tacacgcaca cacttgcttt ctggaattgt aaaatgcccg
     3841 atatgtggag tgggaatgtt tgggaacaag tgtatcaaga aaaagaaaga tggcacaaag
     3901 tataaagatt tttattacta tggttataaa cataggcaga tgataagagg tcataagtgt
     3961 acattcagta agcaaattag agaagaattg ttagatgatg ctgttgcaga ggtgattgtc
     4021 aagatagtaa gtaatccgaa atttgcttct atgatgcaag aaaaaatcaa catgaaggtg
     4081 gatacctctg aaatagaaaa agaaatagat aattaccaaa aggaattgag aaagagtcat
     4141 tctacaaagt ttaagctaat tgaggaaata gataatttag atgttgaaga taagcattat
     4201 aagagaagga aacaggattt agatgataga ctatatcgta tgtatgacaa aatagatgaa
     4261 ttagaatcat cactaattga tgcgaaagca aagaaacaga ctattgaagc tgaaaagctt
     4321 acaggagata acatatataa ggttctgatc tattttgata agctctataa agtcatgaat
     4381 gatgtagagc gtaggcagtt aatttcagct ttgatttctg aaattcaagt ttatgaagaa
     4441 aaacaatcta acggacaatg gctaaaatcc attactttta agctaccaat tatagaagaa
     4501 aatctcaaca taggtttgga taatgatgaa caagttgaat gtgtaagttt attagagaaa
     4561 cgtagttaat cctcaaaagg ttccccaaac cttttgagtc ccactgacgc atcacgctga
     4621 ggcggtatca ctgcttgtac gagttgaagc atcagcgaag taaaagtaga tgttcagcca
     4681 atgcgacgag gtgagaccga aggtcgataa ggtgtgttct gggtatagga ctcgtaaagt
     4741 aagtaggaaa tatgatgaga tgatacagag agcatgaatt ggtcaggtga cgtgcttatt
     4801 tacattagcc tgataatgaa aatggagaga ttatcgatgg ttatattgga attgtaccaa
     4861 aatgattatt ctaaagattt agtagcattt gattccatag aagatgggaa agcctttgta
     4921 gctcaaatcc cgggatacac tctggaaaca gaagatggtt ttgaagtgga gtattttaat
     4981 cctaaaaaca taccggatta tatggaaatt atttttaacg gaaatattgt tcctttatct
     5041 aaatttatgt tcgatcctga ggaaaatgta aacattattt ggaaagagat ttcaaattta
     5101 tccctcaaaa atgatagagt gatcgaagga tattcaaaaa ttgatgcata tgtcgttaac
     5161 aaccatgaag ttaaagccta tgtcgaaaca agagaaacga actatcgtaa agcaaaagac
     5221 ttcttagaaa gccgcggata tgaaatcgac agaagctttt tcggaagtga agacggtgaa
     5281 gcgattcttt acagaaaaaa agggatcgaa gtttggcatt tcttgtgtca cttagaccca
     5341 atgtttgtag agattgaaga tgtagaagga tatgttaaag aagaagttgg agagattcaa
     5401 tagtcaacca aagttccttg tgagtatata cctttgctag taaaagagtc aaaacgttat
     5461 aacgaagggg ggaagaaaac ccttgagtgt aagtcttttt cttgtttaga gggaaagtat
     5521 tagagtagcc gctcataatt tatactagat ttgataactg atttgagaca gattttattt
     5581 ctataaatat tgtgaaaatt ttttaatacc aaagatttaa agttactgtg ttaaaaatcc
     5641 tctccacttt taaactaatg tattataaaa gccagttgac acaagtgtta cacctatgat
     5701 agaattaact tgaggtgatg aaaatggcaa ccgataaaaa tagaataatg attagcttgg
     5761 atgataaaaa tctagagaaa cttgaaaatt tagtagaaga tgctagagat agaaggggaa
     5821 tgcgactaac aaagtcccag gttattgaat tactcctaaa taccgttgat tatttcgatg
     5881 atattatggg ggctatttac tcaaaaaaat aagagcaaaa ttgctattat tttttacaaa
     5941 ttggtgtaac actagtgata taggagtgat gaaatggttg tttatattag acaaagtaaa
     6001 ttaccaagtg aggtttcaat taataaatac aatgctcaag taggtgccta cttacaagga
     6061 gaagaagtta ttttatatca atctttttct gaaataaaag agttaacaag tgaagatata
     6121 gttgtagatt atataatgga gactagagca ttactaaaaa tgatgggctt aaacgttccg
     6181 gttcatgact atcctattga gcttaaagag ttttatggtc gaaagattta tgctggtatt
     6241 ttaggagaga ttgtgaatat acctgataat tggggaaaat ttattaagcc taaagctggt
     6301 tcaaaagtct ttactggaag agttgttaat ggaacccatg atttaatagg tattggtcta
     6361 cctttcgact atcctatatg gattagtgag gttgtagaat tcatagctga atggcgttgt
     6421 tttgtgttag atggtcgcgt attagatgtt cgaccctata caggtgatta tcatgcacaa
     6481 tttgatgcaa gtgtaattga tgaagcgata tcatgttgga aagatgcgcc aatagcttat
     6541 ggactagata tcggtgttac tcgcgatggc agaacacttg ttgttgaagt aaatgatggt
     6601 tatgcattgg gaaattatgg cctatctcct ttaaaatcaa tcaattttca tagagctagg
     6661 tggaaagaaa tggtaaaacc ctattttgaa aaaaatgaaa tttttaaaat ccaacaggat
     6721 gttattttct aaaataaata tggtagataa ccaatataaa aagcatcaaa atgaacaagg
     6781 aggaatctga tgcttggagc aattattgga gatattgtcg gttctgttta cgaatggaac
     6841 aatatcaaaa caaaggactt tcctttattt cggaaggact gcttttttac agatgacacg
     6901 gttatgacct gtgctgttgc agaagcaatt atgaatggtg gacaaaaaga cgacttcatt
     6961 gacgcgatga agaaatatgg cagaatgtat ccgaatgctg attacggtgc tcggtttaat
     7021 gcatggctaa acagcgataa ccgtgagcct tataatagct ttgggaatgg atcagctatg
     7081 cgtatttctc catgtgcttg gatcatggac tgtggttttt atgcgaaaac tggtatatgg
     7141 ccatcatcta gaggacttac gagtctttct gcagaggtaa ctcataatca tccagaaggt
     7201 gtcaaaggcg ctatggctac agctgatgct atctttctat gtcgttttta ctttggtggt
     7261 tattgtagag agtacgagca atcaattaac gacaatccta cagagtgtaa aagacgaatt
     7321 aaggattata tagaaaaaga atacgattac aatctatctc aaactttaga tgaaatccgt
     7381 cctaactatc gttttaacga aacatgtcag gaaactgtcc ctcaagccat tatcgccttt
     7441 cttgaaagta gagacttcga agatgcgata agaaatgcca tctcacttgg tggcgacagt
     7501 gatactctcg cagcaatcac ttgtagcata gcagaggcag cttacggtat tcctgattgg
     7561 atcaaggata aggcctattc ttacttggat gaacccttaa aggatgtagt taggcgatgg
     7621 gaaaatagaa taaaagcgta ttaatctcca gtacgtcaga tttctctttt ctgtattttc
     7681 attgtataat aggattacat ttacttgcat acgacgaaat gtaaacattt ctgtttaaaa
     7741 ttaaggataa aatcaatgaa aaaagcaatg gtaattatca accctacttc tggtggcgag
     7801 aaggctttgg attacaaaga aaagctggag aataaagcaa aagaatactt tgaatatgtt
     7861 gaaaccaaaa ttaccgaaaa agcgctggat gcaacacatt ttgctgaaga agcttctcgt
     7921 gagcagtatg atgcagtggt tgtgtttggt ggagatggaa ctgtcaatga agtcatttca
     7981 ggtattgatg agagagacta cattcctaag ttagggatta tcccaggcgg tacgggtaac
     8041 ctcattacaa aacttttgga aatcaatcaa gacatcgatg gcgcaattga cgaactggat
     8101 tttgatttaa ccaataagat tgatatcggt aaagcaaatg acaactattt tggttatatc
     8161 tttagtatcg gttctctgcc tgaggcgatt cacaatgttg aaatagagga caaaacaaaa
     8221 ttcggtattt taacctatgc tgtaaatacc atgaagtctg tcatgacaga tcaggtcttt
     8281 aacattaagg ttgagacaga aaatggaaat tatgttggtg aagctagcca tgttttggtc
     8341 cttttgacaa attacttcgc tgataagaaa atctttgaag aaaacaagga cggctatgcc
     8401 aacattttga ttctgaaaga tgcctctata ttctccaaat tatccgtcat tcctgattta
     8461 ttaaaagggg atgttgtcgc aaatgataat atcgagtata tcaaagcgcg taatattaaa
     8521 atctcttcag atagtgaatt ggagtcagat gttgacggag ataaatcaga taacctacct
     8581 gtagaaatca aagtcctagc tcagcgagta gaagtatttt caaaaccgaa agaggattag
     8641 tatatagaga aagccttttt taaggctttt tgtatacttt aaaagatagt tcctttaaca
     8701 acggacattc cttgcaaata gtttacaaaa atagtatact ggatttattg agtttgaaaa
     8761 cgtttgcgta aaatttgaat gaatacttta ggagacaaat tgatggaatt gagtgctatt
     8821 taccataggc ctgagtcgga gtatgcctat ctttataagg ataagaaact ccatattcga
     8881 attcgaacta agaaagggga cattgaaagc atcaacttgc actatgggga cccttttatc
     8941 tttatggagg agttttatca ggatacaaaa gaaatggtca agataacttc tggtacctta
     9001 tttgaccatt ggcaggttga agtgtcagtt gactttgcac gtatccagta tctctttgag
     9061 ctcagagata cagaaggtca aaatattttg tatggcgata aagggtgtgt ggaaaattct
     9121 ctagaaaatc ttcatgcaat tgggaatgga tttaagttgc cttatcttca tgagattgat
     9181 gcctgcaagg ttgactgggt ttcaaatacg gtatggtatc agatatttcc tgaaagattt
     9241 gccaatggca atgctctatt aaacccagaa gggactttag actgggattc atctgtcaca
     9301 cctaagagcg atgatttctt tggtggtgat ttacagggga ttattgatca tatggattac
     9361 ttgcaagact tgggtattac tggactatat ctttgtccca tctttgaatc tacaagcaat
     9421 cacaagtaca atacgacaga ttactttgaa attgaccgtc attttggaga caaggagacc
     9481 tttcgggaac tggtggatca agcgcatcat cgtggcatga aagtcatgct ggatgcggta
     9541 tttaatcata ttggttcgca atctcttcaa tggaaaaatg tcgtcaaaaa tggtgaacag
     9601 tctgcttata aggattggtt ccatattcaa caattcccag tgacaactga aaagctagtt
     9661 aataagagag acttacccta tcatgttttt ggtttcgagg actatatgcc taagctaaat
     9721 acagccaatc cagaggtcaa gaattatctt ttaaaggttg cgacttattg gattgaagag
     9781 tttaatatcg atgcttggcg tttggatgtg gctaatgaga ttgaccatca gttctggaag
     9841 gattttcgta aggcagtttt agctaaaaat cctgatcttt tcgagattat aaaaaatata
     9901 aagaatctag tcataaattt gaattgaaac aacgtcttta ttttttgctt cagcaatcta
     9961 aatcgtttga tgatttttta gagaaagcaa agcagttgca tgttcagatt gattttagtc
    10021 aaaagcatag ccgttttttg atgacagata gaacgatgat aaaaccaatt cgagggcgcc
    10081 aactcagcaa acgagatcta tatgatgaag aattttttag aacgcatttt gctaagcaag
    10141 agattgaaag tcgtttagaa tttttgttaa accgtgtcaa ttctttagaa gatttaataa
    10201 caaaagcaaa agaattgaat ctaaccattg acttaaaaca aaaaatgtaa cttttatcct
    10261 ggaagaaaat aatcaaaaga taagtttggg tcatcaaaaa ataagtgata agaaattata
    10321 tgatgtcaaa ttttttcaag attattttaa aaataaggaa gtcgttgctt cagaaggatt
    10381 agagaattta caggaacagt accatgcttt ccaagaagaa cgagataagg ataaagtatc
    10441 cactgaagag attgagaaag cctttaagac atttaaggaa aaatgagata ccgttcgtga
    10501 atttgaagtg gaacttgcag agaaccaaat agagaagcta gttgataagg gcgtctatat
    10561 caaggtgtct ttcggtgtca aacagagcgg tcttattttc attcccaact atcaattgga
    10621 tattatggaa gaagaaaatc ataaaaaata taaagtctac attcgagaaa cgtcttctta
    10681 ctttgtctat aataaagaaa acatggataa taattgtttc atcaagggta ggaccttaat
    10741 cagacaattg agcaacgata gccaaaaact cccctataga cgaccaactt taaaaagtct
    10801 tcaagagaag atttctgaaa ttaatcttat gattgaacta tctaacacga acaaacaata
    10861 ccaagaaatc aaagatgagc atgtattaga aattgcagag attgatatga agctagaaga
    10921 aacccaagaa aaaatcgcca ccttaaacaa gatggcggaa gtccttatca atttgaagag
    10981 tgaagatcat gagactagaa aattagctaa gtatgatttt gaccaaatga acatgacgga
    11041 atcaataatg ttagatcgac tcaatacaga tattttaaaa ttacaacagg aacttggtaa
    11101 tgaaattaat aaatatgagg agatagctag aagattggat ttgtttgtga aaattattaa
    11161 taccaataaa tttacagttc taaaatttca cgagaatgcc ttactagaat aatattattt
    11221 acgactaatt agttaaaaga tagagaatca tttcatttat tgtttacaag tttatcaaaa
    11281 tggctagtat agtgtaattt taacttgtct tctcctaaaa tatcgagaac ttgtatagct
    11341 tgtttcattg tttcaatacc actacttaat tgacgtttaa attcatagta accggttgca
    11401 tagagaaaaa ctgtctgttc ataaaagttt aattcattct ctaacaatcc ctttatctca
    11461 ttaattaaat aagagcaatt agaaaattct tctttatcta tgctgagaat gaaacaattt
    11521 atagctagct gagtgacaat ccgcttattt gttttattta gagatgagta aatataatta
    11581 tttaacattt ctttagttaa taagaagtag gagttgtagt taattgttcg tacacagtta
    11641 cctaataaaa taatctcata ataaccccat ttttcaactt taaagagata atctgctagt
    11701 tgaagtaatt catcatctga tggaatgatt cttgaatcca ttgtgtgtaa aatggatttt
    11761 accattgttt tttcaaaaga atctaaagtg taatttgagg aatccgaaag tagagattgt
    11821 atattattga tgttttgtaa tgaatattgt ttacggatat actgtattaa gttggcaaat
    11881 gactcagttt ttgtatagtc ttcatcgtgt aaaataagaa actcatccaa agtaatgtgt
    11941 aatttgtcta aaatattgat cagtcggata catgatatct ctgactctcc acgttcaaat
    12001 cgggatattt gcgattttga aagatgctca tcagcaacag agcatagact gatttgtttg
    12061 cctttacgaa cttttctaag tgtgatgcca agttttgatt tcatagtttt tcccattctc
    12121 ccaacaaaaa gttaacttag ttttatttat tgtacaataa ataaaaattg aaaggaagtc
    12181 taaatatgaa gaaaatttca aaatttttcc caattttgat gctagtgatg gacattatca
    12241 ttattgttgg tggttaaatc acttaggtgt acacctaagt ctttagagta tctaaagact
    12301 atacttacta gctaaaacat atttaagtta aatcgtaaaa ttttagagag tggtgagact
    12361 ttgaaacata aaaaagtatt aattataggg tatggtataa tgactcgggg tatattaaaa
    12421 atcctgaaac agtcga
//
LOCUS       DBJKQU010000051        12052 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.051, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000051 DBJKQU010000000
VERSION     DBJKQU010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.051"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            129..1622
                     /locus_tag="ACSUUC_001725"
     CDS             129..1622
                     /locus_tag="ACSUUC_001725"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HHQ8054894.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..2162
                     /locus_tag="ACSUUC_001726"
                     /pseudo
     CDS             1635..2162
                     /locus_tag="ACSUUC_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756143.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            2174..2679
                     /locus_tag="ACSUUC_001727"
                     /pseudo
     CDS             2174..2679
                     /locus_tag="ACSUUC_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756128.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            2811..3047
                     /locus_tag="ACSUUC_001728"
     CDS             2811..3047
                     /locus_tag="ACSUUC_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HHQ8054895.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            3044..3457
                     /locus_tag="ACSUUC_001729"
     CDS             3044..3457
                     /locus_tag="ACSUUC_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HHQ8054896.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            3575..4540
                     /gene="xerA"
                     /locus_tag="ACSUUC_001730"
     CDS             3575..4540
                     /gene="xerA"
                     /locus_tag="ACSUUC_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HHQ8054897.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            4563..5144
                     /locus_tag="ACSUUC_001731"
     CDS             4563..5144
                     /locus_tag="ACSUUC_001731"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HHQ8054898.1"
                     /translation="MFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTK
                     NVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRI
                     NSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQ
                     NEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            5174..8524
                     /locus_tag="ACSUUC_001732"
     CDS             5174..8524
                     /locus_tag="ACSUUC_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HHQ8054899.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYCATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISDQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            8795..9040
                     /locus_tag="ACSUUC_001733"
     CDS             8795..9040
                     /locus_tag="ACSUUC_001733"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054900.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     SKHGFEVVDETDEVSNHTYGKATLTRIEEIFEEYKSS"
     gene            complement(9134..9604)
                     /locus_tag="ACSUUC_001734"
     CDS             complement(9134..9604)
                     /locus_tag="ACSUUC_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HHQ8054901.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(9621..11894)
                     /locus_tag="ACSUUC_001735"
     CDS             complement(9621..11894)
                     /locus_tag="ACSUUC_001735"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HHQ8054902.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         3977 a         1904 c         2500 g         3671 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga ccagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcca
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaagtcata ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attggaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt ttgtgagatt ttatctggtt
     1681 acgcttttaa atcatcacaa tttaatgata acaaaattgg tctcccctta atacgaattc
     1741 gagatgtaga aagaggtttt tctgatacct actttgaagg aacttatccc gaagaatatc
     1801 ttattaaaaa tggagactta ttgattacaa tggatggcag ttttatattg aaaaaatggg
     1861 agggggattt agcgctactt aatcaacgtg tctgtaaaat taaaattacg gataaaagtg
     1921 tagatgaagg ttatatatct tggttgattc ctaaattttt aaaagaaatt gaagataaga
     1981 ccccttttgt tacagtgaaa catctttcag tagctaaaat aaaagatatc tcatttgtat
     2041 tgcctaataa actagaacaa aagctaattg caaaaaaact aaatacgata agtcaaattt
     2101 atgattttcg taaaattcaa tcagaaaaat ttaacgagct cgtcaaatcc cgatattccg
     2161 aggaggtggt tgcatgaaga aagtgaaatt agggcaagtg gctactttta tcaatgtaaa
     2221 cctcaagatt ggtcatctga agggaaagag attatcagaa tacagaatct gactaaaact
     2281 tcaaaaggga taaattatta ttcgggtacg attgataaaa aatacattgt tgaagctggt
     2341 gatattctta tttcgtggtc gggtacatta ggggtttttc agtggtgtgg aagatccgca
     2401 gtgttaaatc agcacatttt taaagtggtt tttgataaga tagatataga taaatcgtat
     2461 tttaaatatg ttgttgaaaa aggtttacaa gatgctgtaa aacatactca tggttccaca
     2521 atgaaacatt taactaaaaa atattttgat aatattatgg tttcatatac aaatttggga
     2581 gagcaacaaa gaattgcaag tgagctggat ttgttaagca agctgatttt aaggagacaa
     2641 gaacaacttg aagagcttaa tctacttgta aaatcacaat tggcaatcca aaaatctctg
     2701 gaagaacttg aaactttgaa gaaatctctg atgcaggagt attttggctg atattctgcc
     2761 attgtaatta cggtaatgat ttgttataat acttcaaagg aggaaatcag atggtagtaa
     2821 aaacaagaaa acaaggaaat tcaatcacca ttacgattcc aagtgaattt aatattccaa
     2881 gtggtgttaa atacgaagcg aaattgttac caagtggtga gattatcttt actcctgaag
     2941 aattggggca gcaggtttct tatgtatctg atgatgcctt tgacttaaat ttagataaaa
     3001 tatttgacga atacgacgat gttttcaaag ctttggtgga aaaatgacaa tctatctgac
     3061 agaaaagcaa attgaaaaaa taaatgcttt agcaattcaa cggtattctc caaatgagaa
     3121 aattcaaaca gttagttctt ctgccttaaa tatgattgtg aacttaccag aacaatttgt
     3181 ctttgggaag tctctttatc caacaatttt tgataaagca acgatactat ttgtccaatt
     3241 gataaagaag catgtttttg ctaatgctaa taaaagaact gctttcttcg ttttggtcaa
     3301 atttttacaa ttaaacggct atcgtttttc tgtaacggta gaagaagcag taaaaatgtg
     3361 tgtaaccatc gcagtagaag ctttaactga tgaaaaaatg acaagctact ccaaatgggt
     3421 ttctgaacat tctgttagag aaaaggtcaa aaagtaacct agtatgctgg atttgaatga
     3481 gcacaagaaa ataaatgaac agacaatatt agaattctgt aatgcagaaa ctgatattgt
     3541 ctctttttat tgatgaataa gaaagtgaga aattatggaa tcaaaagtta caattatcat
     3601 gcaagaaatg ttacctcttt taaataatga acaattacta gcgttgagag agagtttaga
     3661 acatcatcta gtagacggaa aaaagcagca gaagtattcg aataataacc tgttgcaact
     3721 atttattacc gccaagcagg tagagggctg tagctcaaaa acaattcgtt attaccagag
     3781 gacgattgaa aacttgttta atgctattaa agagtctgtg acacaactca caacagatga
     3841 tttaaggagt tatttagcaa attaccagtc tgaaaaggat tgtagtaagg caaatttaga
     3901 caatattagg cgtatattgt cttctttttt tgcttggctt gagcaagagg aatatatcat
     3961 taaaaatccc attcgacgga taaagaaaat taagactgag caaaatgtga aggaaactta
     4021 tactgatgaa catttggaaa ttatgcgtga taactgtgaa aatttgagag atttggcaat
     4081 aatagaccta ctagcatcga caggtatgcg tgtaggggag cttgtacagt tgaatcgttc
     4141 agatattgat tttgaaaaca gagagtgtgt tgtctttggt aaaggaaaga aggagagacc
     4201 agtatatttt gatgctcgga cgaaaattca tttaagaaat tatcttaacg acagaaaaga
     4261 tagtcaccct gctctttttg taacgctagt tggaaaagcc cagagacttg gaattgctgg
     4321 tgtagagatt cgcttaagaa agttaggaga caaactcggc atacaaaagg ttcacccaca
     4381 taagttcaga agaactttag cgactaaggc aattgataaa ggtatgccta tcgaacaagt
     4441 ccaaaaactg ctaggtcata gcaagattga cacaaccctg gcctatgcca tggtcaatca
     4501 aaataatgtc aagcattcac accaaaaatt catctcttaa aagcaaatcc cgatttaacg
     4561 agatgtttgg ggaaaataaa atatttgaaa gcattgataa cttatttgat attatagatg
     4621 gtgatagggg caaaaattat cctaaatcag atgagttgtt tagtgaggag tactgtttat
     4681 ttttaaatac aaagaatgtt actaaaaacg gattttcatt cgatacaaag caatttatca
     4741 ctaaaacaaa ggataaatta cttcgaaaag gcaaacttga gcgttatgat atagtcttga
     4801 caacaagagg tactgttgga aatgtagcgt actacgatga attaataaaa tataaacatt
     4861 tacgtataaa ttcaggtatg gtaatattac gtcccaagac accaaatcta aatcagaaat
     4921 ttattatcca tgttttaagg aataataatt atagtcgagt gatatcagga agtgctcagc
     4981 ctcagttacc aattacaaaa ttaaaaaaaa tacttctccc cctcccccca ctagccctcc
     5041 aaaatgagtt cgcagacttt gtagtccagg tcgacaaatc acaatttgct tgtgagatag
     5101 ctataaaagt gtggagaaat agcttgaaat ttagtataat atagctaaac tatttgttta
     5161 aagtgagaaa aaaatgggaa attttagctt tcttttaaaa aatgacgaat atgaatcttt
     5221 ttcaaaacct tgcattgaag ctgaaaatat gattgctaca tcaactgtgg ctactgcctt
     5281 tatggcgcgt cgtgctttgg agcaggctgt ccattggata tatagtcacg attcatattt
     5341 agaagctccc tattgtgcta ctctatcttc tttagtatgg gatgatgatt ttagggatat
     5401 cgtagattct gaactccaca agcagatagt tctgttgatt cggtggggaa accatgctgc
     5461 tcatggtggt gaaattaagg aacgagaagc gattttagct ttacatcatt tgtatcagtt
     5521 tgttaatttt atcgattatt gttacagcaa tgaatttgtg gagcgttatt ttgatgagaa
     5581 gtgtttacca ctttcagcaa acatcaaata ccgagaaact ccacaatcta tgataaagtt
     5641 acaagacagt ttaccagaac tgcctgattt tcatgaacag atggctgctc agtccgtaga
     5701 agttcaagag acttatactg aaaaacgtga gactgcagcg caacggcaag atgtgccttt
     5761 ccatattgaa caattatctg aggcagagac aagaaagctc tttattgata tcgatctccg
     5821 tttagcagga tggatatttg aagaaaactg tcgtgttgag atagccgttg atggtctcaa
     5881 gcacggttca ggaattggtt actgtgacta tgtactttat ggtaaaaatg ggaaaatttt
     5941 agcgattgtg gaggctaaaa aagcctctgt caatccagaa gtaggggaag tacaggtcaa
     6001 agaatatgct gaagctttgg agaaacatat cggctatcag ccaatttgct ttattacaaa
     6061 tgggttgaag cactatatac ttgatggtcc gaaccgccgc cagattgcag gcttttactc
     6121 tcaagaagaa ttgcaattag tgatggatag acgtcatctt caaaaaccgc ttgaggatat
     6181 ttctagtaaa attagggacg atatttccgg gcgtcactac caaaaacatg ccattgcaag
     6241 cgtttgtgaa gctttctcta atcatcgtag acaggcactt ttggttatgg caactggggc
     6301 ggggaaaact cgtacagcag tttctctagt tgatatctta tcacgtcata actgggtaaa
     6361 aaacgttctc ttcttagccg atagaacttc cttggttaag caagcctatg attcgtttag
     6421 aaaattactc ccagatcttt ccgtttgtaa cttcttagaa gataaagaag gagctcaatc
     6481 aagtcgtatg gtcttttcaa cttatccgac catgattgga gcgattagtg atcaagaaga
     6541 agtaaatcaa cgccctttta ctgttgggca ttttgacctt atcataattg acgaatctca
     6601 ccgttctatt tatcagaaat acaagtccat ttttgattat tttgatgcaa ggattgtagg
     6661 cttaacagct actccgcgtc aagatttaga taaaaacacc tatggattct ttaatttgga
     6721 gaatggggtt ccaacatatg catatgattt ggaagaggct gttaaagacg gatatttagt
     6781 agcctatcat tctatcgaaa ccaaactgaa actacctacg gatggtctac attatgatga
     6841 tttgtccgaa gaagaaaagg aacattttga tagcaaattt gaagacgata gctgtgaaaa
     6901 agatattgat gggagtgtgt ttaattcctt tattttcaat aaaagtacag tagaaattgt
     6961 tttaaatgaa ctcatgacaa gaggaattca gacagcctcg ggtgatgaaa ttggtaaaac
     7021 tattattttt gctaaaaatc atgaccatgc ggaatatatc agaggtattt ttaacaaccg
     7081 ctatcctgaa aaagggagcg actatgctca ggtgattgat tatagtatta agcattatca
     7141 gaccttgatt gatgatttta aaattaagga gaagtatcct caaattgcga tttctgtcga
     7201 tatgttagat acaggtattg atgtaccaga ggttgttaat ttagtcttct tcaagaaagt
     7261 acgctctaaa actaagtttt ggcagatgat tggtcgagga acccgtctat gtaaagattt
     7321 atttggacct gagcaggata aggaaaactt cttggtattt gattatgggg acaattttga
     7381 ttattttcgt gcagatccaa gagatggaga gggtcgtcac attgtttcgt tgactcagcg
     7441 tttatttaat atcaaagtgg acttgattcg agaacttcag ggacttcaat accaagaaga
     7501 tcagtttgcg agagcatacc gtcagcagct tgtctcggaa cttcaaggtc gtatagagag
     7561 cttaaatgag ttggacttca gggttcgtat ggttttagat acagtttata gctataggaa
     7621 attggaaagt tggcagaatc taactgctgt tacaagtgaa accattcaaa aaaatctctc
     7681 tccgctttta tttgatgaag ataaagaaga tgagatggcc aggagatttg atttgtggtt
     7741 gcttcatatt cagttggggc aactgacagc taaatcttcc actgttcata tttcccaagt
     7801 gatgaagacg gctagagctc tttctgctat tggcaatatc ccgcaggttt ttgagcaggc
     7861 tgaaattatc aggaaagtac aggagcctga attttggaaa gaagttaact tgtctgattt
     7921 ggaaaaaatt cgtcttgcta ttcgagattt attacagttt ttggataaaa cagaccgtaa
     7981 accctactat gttaactttg aagatcgtat actctccact gttcacgaga ccacagcatt
     8041 tttgcaggtc aacgatcttc ggtcttacaa tgaaaaagtt gagcattatt tgaaaactca
     8101 tctggatgag gagtccattt ctaagctata ccataataaa aagttgacat ctgatgatat
     8161 gcttgcactt gaaaaattgc tctgggaaaa attaggtagt aaagcagact accaaagtca
     8221 ttatgaaaat aaggcaattc cgagattggt tcgtgagatt attggcttag atagagagtc
     8281 tgccaatcgt attttttcta aatttttgtc ggatgagaat cttaatgcca ggcagatttc
     8341 atttgtaaaa ttgattgtag actacattgt agaaaatggt tttttagaga cgaaagtgtt
     8401 aacgcaagag ccgtttaaat cttatggttc tgttcaacta ctcttccaac accaactacc
     8461 agtacttcgt aatattgttc aaatcattga acttatcaat aatcgagctg gagaagcggc
     8521 ttaaattcta aagtgattgc catgctgaga ctcatttaaa attaaaaaga gtagaaattt
     8581 atgctatata tgagaagttt tattaggaag aatgtcatcg ttttcctaga atacagtatc
     8641 agttgttaag tggttgataa atttcaaagt agatacttgt accacgatgt ttgttgatcg
     8701 agttattaac aaaagagcta ctttgatttt aaagaaatag aaaacaaaaa gctgagcaag
     8761 aattcaattg caggagaaaa tgaaataata ctcaatgaaa atcaaagagc aaactaggaa
     8821 actagctgca ggctgctcaa aacactgttt tgaggttgta gataagactg acgaagtcag
     8881 ctcaaaacat ggttttgagg ttgtagatga aactgacgaa gtcagctcaa aacatggttt
     8941 tgaggttgta gatgaaactg acgaagtcag taaccatacc tacggcaagg cgacgttgac
     9001 gcggattgaa gagattttcg aagagtataa atcttcctag gatagagcaa aacgcatagt
     9061 atcaagggtt ttctgatgtt aaagactttc taccaggttt ttttaaagca taattgttag
     9121 ttgtagtcat ttattattct tcaaagaaaa atggtggggc gaattttttc agttcttcaa
     9181 agcacttttg agcagtatct gcatcttcac agatgataag acagacatca ttaccacaaa
     9241 gggtagcgat agcgtcaggg aagctcaaag tatcaatgat agaaccaaag gattgagcca
     9301 gtccaggaag ggtttttagt aggacttggt gttgaactgg gcgcatccag acaagggcgt
     9361 cttccatgta gagttcgaga cgtttttccc attttgagat ggaaccattg ttaagaacat
     9421 aataagcgct atcttcttcg cggacttttg ataggttcat atttttgatg tcgcgtgaga
     9481 gggttgcctg ggttacttga atgtcgttct cagcaagaag ggcttgcaac tcagcctgtg
     9541 tatgaatctt gttttttgtg ataagagcgc gtataagttg gtggcggtgt tctgatttat
     9601 tcataataat gtaactcctt ttagcaaggt aaggtaagca tggactgagc gaggtcgaca
     9661 gtcaagtggt agtctgtatt gtcacggatg gtgatttcaa agtcagtagt atagaggact
     9721 aaacggagag tgtctccttc ttttagcttg taaatagttg gctgcagttc aaattgaacg
     9781 tccatccatt catctgcagt aatatcctct actaacagta aatcatttct attttgtaaa
     9841 ttaaggtaac cttttgtcac gactcgttgt gcctctggtc taaatggcaa ttcacagaga
     9901 ttttccaaca tgtgatagcg accgttatca atggttctag cacttaaaat agctggataa
     9961 ggttgtaggt atttcttttg cccaaattct agcagttggg cagataagag ccccttgttt
    10021 gtactggatt tgatacgaag attgagctga gcgcgaccgt ttaggtggag atctttagtc
    10081 acaggaaggt taatagtaat ctgattggct ttcccttgat agagctctgt attgaaggtt
    10141 tggtatgtct taccatagcg ctcaaaatcc ttatctgggt actggttttg aatagcttgc
    10201 tcttcttgac caagtgagaa ggtttcacag ttttcttgcc caccgaagtt atcaagtgat
    10261 aaccaagtct gtggagctgt attgtcctgc cagataacag taggaagttg aaagtctgtt
    10321 tcctgtccta gtaatttctt ggtcaataag gcatttatgg actcacggaa gtcaattgat
    10381 tgccaattgt tcatgtaaac atgagcacca ttatggaaaa agagatgctt gtgtatatga
    10441 gtaggaagag catggaacat ctggtaaaca tgaagtggtt tgacattcca atcctgagaa
    10501 ccatgagtaa agacaacctc tgcctttact ttatgggcat tgagcagata attgcggtca
    10561 tgccaaaact gattgtagtc cccagttttt cggtctagct gagctttcac tttttctaag
    10621 tcagcttggt gagcttcatt gccacggata tagtcgccag ctaagagatt acgagaatag
    10681 gttaactcag caagggagtc aaagtcctca cctggataac cacctgggct agtcaccaga
    10741 ccgttttcac ggtagtagtt gtaccatgat gaaattcctg cctcggcaat gataacttct
    10801 aaaccatcga ctcctgtagt cgcaagacca ttggacatgg tacctagata ggaaagtcct
    10861 gttgtagcaa cttttccgtt tgaccaatca gccttgactt gacgctggcg cgtgtgatca
    10921 gtaaaggcac ggcaacggcc gttaagccaa tcgatgacat ttttataagc ctcgatttgc
    10981 tggtagtctc cattagtcat gaaacctgtc gagtctttgg taccaacacc tgagacatag
    11041 agattggcaa agcctctcgg aaggaagtag tcgtttagtg tatagctaga gttgatgtga
    11101 gttagctttt cctcagcctc tgctataagc tcagctttac cttggggttg gacgagattt
    11161 agttgaggtt tctctagctc aatcttgtga ggaagcttaa cctcaagctc gccctccatc
    11221 ttgtagagag ccttgtcact agccttgtca ttggttccct gatgataagg gctggctgtc
    11281 atgatggcag ggatttttcc atcaaaacga gggcgaataa tgctaacctt tactaggtct
    11341 gatagccctt tttggtcagt atcgacacga gactcaacgt aaacgacttc acgaatgaca
    11401 tcctggttag aaaaagtagc caaactcttg ccgttaaagt agtggtagtc attatcctcc
    11461 ggaataagac catcactaac aagttggtcg ataagagtat ttcctttttt ggtgcgagta
    11521 ttgagtaact gatagagatt ttcaatcaag tcaccatata taatgggaaa tccagtttct
    11581 ttacgaaaaa cgtcactatc ttcgaagtca accaaataag aaaagcctaa aagttgaaaa
    11641 gcaacagtat aaaaaatatc tgctgtcagt tcatcttctg attgaaaaaa tgtcagcagg
    11701 tctgtttttt tatcagctgc taggatagaa agtgggtagt tggtgtcttg ataagtgaaa
    11761 aagaaacgac gtaaaaaggt ttcaagtgag tctttgtgat tggctgtatt ttgtaaatca
    11821 aagccacatt tttttagttc agataagaca ttttcttttg gaaaattgat ataactatat
    11881 tgattaaaac gcatagaacc tccatataga atgacagtta aggttattat atcaaaaaaa
    11941 aagcagaaag ggaattgtta acttcaaaag gaaataatcc aataaaaatg aataaagtac
    12001 taaattcaat atagagaaca gagtaacaat aagaataaat agatagggta ta
//
LOCUS       DBJKQU010000052        11902 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.052, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000052 DBJKQU010000000
VERSION     DBJKQU010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.052"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            161..814
                     /locus_tag="ACSUUC_001736"
     CDS             161..814
                     /locus_tag="ACSUUC_001736"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HHQ8054903.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANTFLKETGQEPIDWLR"
     gene            824..1288
                     /locus_tag="ACSUUC_001737"
     CDS             824..1288
                     /locus_tag="ACSUUC_001737"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHQ8054904.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPELDWYTYVFKVTEFEGDLIDCNEGM
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1301..2569
                     /locus_tag="ACSUUC_001738"
     CDS             1301..2569
                     /locus_tag="ACSUUC_001738"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HHQ8054905.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGHVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2583..2843
                     /locus_tag="ACSUUC_001739"
     CDS             2583..2843
                     /locus_tag="ACSUUC_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054906.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2854..4215
                     /gene="pdrM"
                     /locus_tag="ACSUUC_001740"
     CDS             2854..4215
                     /gene="pdrM"
                     /locus_tag="ACSUUC_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HHQ8054907.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4369..5337
                     /locus_tag="ACSUUC_001741"
     CDS             4369..5337
                     /locus_tag="ACSUUC_001741"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016624 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, disulfide as
                     acceptor [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HHQ8054908.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5353..6345
                     /locus_tag="ACSUUC_001742"
     CDS             5353..6345
                     /locus_tag="ACSUUC_001742"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HHQ8054909.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6563..7606
                     /locus_tag="ACSUUC_001743"
     CDS             6563..7606
                     /locus_tag="ACSUUC_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - pyruvate decarboxylation to
                     acetyl-CoA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HHQ8054910.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGIQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7652..9355
                     /gene="lpdA"
                     /locus_tag="ACSUUC_001744"
     CDS             7652..9355
                     /gene="lpdA"
                     /locus_tag="ACSUUC_001744"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     (NADH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HHQ8054911.1"
                     /translation="MALEIIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            9419..10408
                     /locus_tag="ACSUUC_001745"
     CDS             9419..10408
                     /locus_tag="ACSUUC_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HHQ8054912.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10475..11545)
                     /gene="xerS"
                     /locus_tag="ACSUUC_001746"
     CDS             complement(10475..11545)
                     /gene="xerS"
                     /locus_tag="ACSUUC_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HHQ8054913.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         3544 a         2223 c         2656 g         3479 t
ORIGIN      
        1 tttaaaaagt aattataaaa aatagccagt ctttataaac tgtattcacg tattcaaatc
       61 gtatatagtc gatttattaa atctttagat aaactgtaaa aagtggtttc catagccact
      121 ttttgctata atagaggcag taaaaatgaa ggagtcggct atggaacact cgtcttggca
      181 tgctttgatt aaggcgcaat tacctgaggg ttatttcggg aaaatcaatc agtttatgga
      241 gcaggtctat tctcagggga ttatttatcc acccaaggaa aaggtttttc aggctctctt
      301 gacaacactg cttgaagaag ttaaggtggt aattctaggg caagacccct atcacggacc
      361 aggtcaagcg cagggcttga gtttttccgt acctgactct atcccagctc caccatcctt
      421 gcaaaatatc ttgaaagaat tgtcagatga tatcggagtt aagaaatctc atgatttgac
      481 agcttgggct gagcaaggag tcttgcttct taatgcttgt ttgactgttc ctgctggaca
      541 ggccaatggt catgctggtc aaatctggga gccttttact gatgctgtga ttcaggtggt
      601 caatcatcta gatagaccag tcgtttttgt actctgggga gcttatgcac gtaagaagaa
      661 ggccttagtt accaatcctc atcacttgat tattgaatca gcccatccaa gtcctttgtc
      721 ggtttataga ggattttggg gttccaagcc tttttccaag gccaatacat tcttaaaaga
      781 gacaggacaa gagccaatcg attggcttag ataaggagaa aatatgcctc agttagcgac
      841 gatttgttac attgataatg ggaaagaact gctcatgctc catcgtaata agaaacccaa
      901 tgatgtccat gaagggaaat ggattggtgt gggtggtaag ctagagagag gagagacgcc
      961 ccaggaatgc gcggtacgtg aaatccttga agaaacaggg ctcaaagcca agccagttct
     1021 aaaaggtgtc atcacttttc ctgaatttac accagaatta gactggtaca cctatgtttt
     1081 taaggtgacg gagtttgagg gcgacttgat tgactgcaat gaggggatgc tagaatgggt
     1141 tccctatgat gaggttttga gcaagccgac ttgggaaggt gaccacacct ttgttgagtg
     1201 gcttttagag gataaaccct tcttttcagc caagtttgtt tatgatgggg ataaattgtt
     1261 ggatacccaa gttgatttct atgaataaag gagaaagcag atgctactaa tcaaaaatgg
     1321 tcgtgtaatg gatcccaagt ctggtttgga tcaagtttgt gatgtcttag ttcaagatgg
     1381 gaaaattatc aaaattgcgc ctgagatcac ggaagaagga gcagaaacga ttgatgctac
     1441 tggtcatgtg gttgctcctg gtttggtcga tattcatgtg catttccgtg aacctggtca
     1501 aacacataaa gaagacattc atactggtgc cctagcagcc gctgcaggtg gttttactac
     1561 tgtcgtcatg atggctaata ccagtccaac catttcagac gtggagactt tgcaagcagt
     1621 tctccagtca gctgccaaag agaagattaa tgtcaagaca gttgcgacca ttactaaaaa
     1681 ctttaatggt aaaaacttga ctgactttaa ggcactttta gaagctggtg cggttggttt
     1741 ctctgatgac ggtattccgc ttgagagcag taagattgtc aaggaagcca tggaggaagc
     1801 caaaaaactc aataccttta tcagccttca tgaggaagat ccaggtttga acggtgttct
     1861 tggctttaat gaaaatattg ctagagaaca tttccatatc tgtggtgcta ctggggtggc
     1921 tgagtacgct atgatggcgc gtgatgtcat gattgcctat gcaactaaag cccatgttca
     1981 catccagcat ttgtctaagg aagaaagtgt taaagtagtg gagtttgctc aggggttagg
     2041 tgcagaagtc acagcagaag tagcaccaca gcatttctct aagacagaag cacttctttt
     2101 aacacaaggt agcaatgcta agatgaatcc accgcttcgt ttggaatcag accgtcgtgc
     2161 cgttatcgaa ggtctcaaat caggtgtcat cacagttatt gcgactgacc acgcgcctca
     2221 tcatgtagat gaaaaaaatg ttgaagatat taccaaagcg ccatctggta tgactggctt
     2281 agaaacatcc ctgtctctcg gcttgaccta tttggtagaa gctggtgagt tgagcttgat
     2341 ggaattactt gaaaaaatga catacaaccc agccaagctt tacaacttta aagcaggtta
     2401 cttggctgag aatggtccag cagatatcac tatttttgat gccaaggctg accgccttgt
     2461 ggactcccat tttgcttcca aagcagctaa ttcaccattc atcggtgaaa ccttaaaagg
     2521 gcaggttaaa tataccatct gtaagggaca aatcgtctat caagcttgat aggagttaga
     2581 atatgaatta ttttcgaaaa cgtagggaga gacaagcgaa atctaatagt ggaatttact
     2641 gtcccgcagc taatcgttcc aaaattcaat atgaaactaa agaaaaagct gaccatgcgg
     2701 ttcaatatga taacggaggt ttagttagaa gctattattg tcgtacatgt gcgtgttggc
     2761 atactacttc aaaatctaat aaacctccgc taagtttgaa aaactatggt ctgaaactct
     2821 ttggtttaga taaatcagaa tagaaagaga agtatgtata agacaaagtg tttacgagag
     2881 aagttagtat tatttttaaa aattttcttc ccaatcctga tctaccaatt tgccaattat
     2941 tctgcctctt ttgttgatac tgcaatgaca ggtcaataca acactatgga cttggctggt
     3001 gtatctatgg caaccagtat ctggaatcct ttctttacat ttctaacagg gattgtgtca
     3061 gccttggtgc ctatcattgg tcaccatctt ggtcgaggca aaaaggaaga agttgcgtct
     3121 gatttttacc aatttattta tttggccttg ggcctatctg tggtcttgct ggggatggta
     3181 cttttcttgg caccaacaat cttgaatcat attgggttag aagcagcagt agcggcagta
     3241 gcggttcgct atctttggtt tttatctatc gggattatcc ccttgttgct ctttagcgtc
     3301 attcgttcct tgctggattc gctgggcttg accaaactgt ccatgtacct catgcttttg
     3361 ttactccctc tcaatagcgg atttaactat ctcttgattt acggtgcctt tggtgttcca
     3421 gaactgggag gggctggtgc tggtttagga acatccttgg cctactgggt cttgcttggg
     3481 atttctgttc tggttttatt taaacaggag aagctcaaag ccttacacct tgagaaacga
     3541 attccactta atatggataa cattaaggaa ggagttcgtt taggtctgcc tattggggga
     3601 actgtcttcg cggaagtggc tatcttttca gtggttggct tgattatggc taagttttcg
     3661 tccttgatta tagctagtca ccagtcagct atgaactttt caagtcttat gtacgccttt
     3721 cctatgagta tctcatcggc tatggctatt gtcgtttcct atgaagtggg agccaagcga
     3781 tttgatgatg cgaaaaccta tattggtcta ggaagatgga ctgctctcat ttttgcggcc
     3841 ttcaccctaa ccttccttta catttttagg ggaaatgtgg ccagtcttta tggtaacgac
     3901 ccaaaattta tcgatttgac agcgcgtttt ttaacttata gtcttttctt ccagttagca
     3961 gatacctttg cggcaccgct tcagggaatt ttgcgggggt ataaggatac agttattcct
     4021 ttttaccttg gtttgcttgg ttattggggc gtagcaatcc ctgtggctac gctatttgat
     4081 tccctaacag attttggagc ttattcttac tggatcggct tgattattag tttgattgtg
     4141 agtggggcgc tctaccgttg gcgtttaact gtgattatga agagatttga atctttagca
     4201 aaatccaaac gctaaaaagt ttgtgaaaaa atatccttga caagaaaatc ccttgttttc
     4261 acggggtttt cttttttatt ttgtgaaatt tcttttagaa aaactttgac agtatttgcc
     4321 aaaaacggta aaatagtaag gtaagaagaa agttagaaag gcaagaagat gtcaacttta
     4381 gataaaaatc ttttgctaga aatgttccgt aagatggaag aaatccgtcg catggactta
     4441 aaaattgcac aattagtaaa gaaagggaaa gtgccaggaa tgacgcactt ttctgttggt
     4501 gaagaggcag ctaacgtggg ggctatgtta gctctcaatc cagatgatct gattacctca
     4561 aaccaccgtg gacacgggca agctattgct aaagggattg acctcaacgg aatgatggct
     4621 gaaatccttg gtaaatacac tggaacctgt aaagggaaag gtggatctat gcatatcgct
     4681 gaccttgatg ctgggaacct tggtgccaat ggtatcgtag gtggtggtat ggggatcgct
     4741 gtcggtgcag ccctcagtca gcaaatgcaa aataccggta aaatcgttgt ttgcttcttt
     4801 ggagatggtg cgaccaatga aggtgttttc cacgaagcag tgaacatggc ttctatctgg
     4861 aacctgccag tcattttcta ttgcattaac aacggttacg gtatctctgc ggatatcaag
     4921 aaaatgacca atatagaaca tatccatcaa cgtagcgccg cttatggaat tcctggaatg
     4981 ttcatcgaag acggtaacaa tgtcatcgat gtctatgaag gatttcagaa agctgtagac
     5041 catgttcgca gtggcaatgg tccagtcttg attgaaagtg taacttatcg ctggctcggt
     5101 cactcatcat ctgaccctgg taaatatcgt acgcgtgaag aagtggaatt gtggaaacaa
     5161 aaagatccaa tcgaaaacct ccgcaattac cttattgaaa ataacattgc aagtgccgaa
     5221 gaattggaag aaatccaagc gcaagtaaag gaagcagtag aagcttctgt taaatttgca
     5281 gaggaaagcc cattcccacc gcttgaatca gcctttgaag atatttacgc agactaagga
     5341 gaaagagata aaatggaaac aaaaacaatg tccttccgtg acaccattat ccttgctatg
     5401 tctgaggaaa tgcgtcgcga tgaaaatgtg ttcttgatgg gagaagacgt cggtgtcttc
     5461 ggaggagact tcggtacttc tgttggaatg cttgaagaat ttggtccaga acgcgtccgt
     5521 gactgtccga tttctgaagc tgccatctct ggagcagcag caggagcagc catgacagga
     5581 cttcgtccaa tcgtcgatat gaccttcatg gacttctctg ttattgccat ggacaatatc
     5641 gtcaaccaag ctgctaaaac acgttacatg tttggtggta aaggtcaggt tccaatgact
     5701 gttcgttgtg cagctggtaa cggagttggc tctgccgccc agcactcaca atctctagag
     5761 tcttggttta ctcacattcc aggacttaag gttgtggcac ctggaacacc tgcggacatg
     5821 aaaggcctgc ttaagtcttc tatccgtgat aaaaacccag ttattatact tgagtacaag
     5881 tcagaattta accaaaaagg ggaagtgcca gttgatccag actacacaat tccacttggg
     5941 gttggtgaaa tcaaacgcca aggaacggat gtaacagttg ttacttatgg aaaaatgctt
     6001 cgccgtgtgg ttcaagctgc tgaagaatta gcagaagaag gaatttcagt tgaaattgtt
     6061 gacccacgta cccttgttcc gcttgataag gatatcatca taaactcagt gaagaagact
     6121 ggtaaggttg ttctggtcaa cgatgcccac aaaacaagtg gctatatcgg tgaaatttca
     6181 gctattattt cagaatcaga agcatttgac tatctagatg caccaatccg ccgttgtgca
     6241 ggagaagatg tgccgatgcc ttatgcacaa aacctagaaa atgcaatgat tccaacagtt
     6301 gaaagtatca aagatgcaat ccgaaaaact tataacaaag aatagagtta cataagataa
     6361 gttatgtaaa taaaataaag ctgacgagaa actttgtatc ttttaggtgc agagctcttc
     6421 gtcattaata tcttagatta gagcacgggc taaaagctcg gaaaaaagat aaatctcctt
     6481 ggcttcatcg aagccatcgt cgatttccta tttttcagtc gcttttgacg ccctttgtat
     6541 cataaataga attggagagg tcatggctga tgacaagcta agagcgactc ctgcagctag
     6601 aaagttagcg gatgatttag ggataaacct ctacgacgtt tctggctcag gtgcaaacgg
     6661 tcgtgtccac aaagaagacg tggaaactta taaagacaca aacgtggttc gcatttcgcc
     6721 acttgcaaaa cgaattgccc tcgaacataa cattgcttgg caggaaatcc aaggaaccgg
     6781 tcatcgtggt aaaatcatga agaaggatgt tttggccctg cttcctgaaa atatcgaaaa
     6841 cgatagcatc aaatctcctg ctcagattga aaaagtggaa gaagttcctg ataacgtaac
     6901 accatatggt gaaatcgagc gtattccaat gacaccaatg cgtaaggtta ttgcccaacg
     6961 catggttgaa tcttacttga ctgcgccaac cttcaccctc aactatgaag ttgatatgac
     7021 tgaaatgttg gctcttcgta agagggttct tgagccaatc atggaagcaa ctgggaagaa
     7081 gactactgta acagaccttc tttcacttgc agttgttaag actcttatga aacatccata
     7141 catcaacgct tcattgacag aagatggcaa gactattatc actcacaact atgtcaatct
     7201 tgctatggca gttgggatgg ataatggatt gatgacacct gttgtttaca atgctgagaa
     7261 gatgagtctt tcagaactgg ttgtagcctt taaggatgtt attggccgta ccttggatgg
     7321 taaattggct ccaagtgagt tacaaaattc aacattcaca atcagtaatt tgggaatgtt
     7381 tggtattcag tcctttggtc cgattattaa ccaacccaac tcagctatcc ttggtgtcag
     7441 ttcgacaatc gagaagccag ttgtcgtcaa tggtgaaatt gtgattcgcc caatcatgag
     7501 tttaggatta accattgacc accgtgtcgt agatggtatg gctggtgcta agtttatgaa
     7561 ggacttgaaa gagttgattg aaaccccaat ctcaatgttg atttaagagc aagagtattc
     7621 atttttaaga tatagataaa ggaaggaaga catggcctta gaaataatta tgccaaaagc
     7681 cggcgtggat atgacagaag gacaaatcgt ccaatggaat aaaaaagtcg gagaatttgt
     7741 aaaagaagga gaaatccttt tggaaatcat gactgataaa gtcagcatgg aattggaagc
     7801 cgaagaagat gggtacttga ttgccattct caaaggagat ggtgaaactg tccctgtaac
     7861 ggaagttatc ggttaccttg gtgaagaaag ggaaaacatc ccaacagctg gagcagcatc
     7921 gccagaagct agccctgtac ctgtagcaag tacctcaaac gatgatggta agagcgatga
     7981 tgcttttgat atcgttgtga ttggtggagg tcctgctggt tatgttgcag ccattaaagc
     8041 tgcccaactc ggcggtaagg ttgcccttgt tgagaaatct gaacttggtg gaacctgctt
     8101 aaaccgtgga tgtattccaa ccaagaccta ccttcataac gctgaaatta ttgaaaatat
     8161 cggtcatgct gcaaatcgtg gtatcgtgat tgaaaatcct aacttcactg ttgatatgga
     8221 aaaactttta gaaactaaat ctaaagttgt taatactctt gttggtggtg ttgcaggact
     8281 tcttcgtagc tacggagtta ctgttcataa aggaattggt acaatcacta aagacaagaa
     8341 cgtcttggta aatggctctg aattgcttga aaccaagaaa atcattcttg ctggtggttc
     8401 aaaagtcagc aagatcaatg tccctggtat ggaatctcca cttgtcatga ctagtgatga
     8461 cattcttgaa atgaacgaag tgccagaaag ccttgttatc atcggtggtg gagttgtcgg
     8521 tatcgaactc ggtcaggcct tcatgacatt tggttcaaaa gtgactgtta tcgaaatgat
     8581 ggaccgtata gttccagcta tggatgcgga agtttctaag aaccttcgct tgatccttga
     8641 gcgtaaagga atgaccatct tgactggtac taaactgcaa gaaatcattg aggaaaatgg
     8701 tcaacttcgt atcaaggttg aaggaaaaga cgatatcatc gcaagcaaag ctcttctttc
     8761 aattggtcgt atgccagacc ttgaaggtat tggagaggtt gagtttgaat tggatcgtgg
     8821 ttgtatcaag gtcaatgaat acatggaaac ttcagttcca ggcatttatg caccaggtga
     8881 catcaacggt actaagatgt tggctcacgc agctttccgc atgggtgaag tttccgctga
     8941 aaatgccctt aaaggaaatc atgcagttgc caaattgaat ttgactcctg cagccatcta
     9001 cactctccct gaagtagcag cagtaggttt gacagaagaa caagcccgtg agaaatacga
     9061 tgttgccatc ggtaagttta actttgctgc taacggtcgt gctattgcat ctgacgcagc
     9121 tcaaggtttc gtaaaagtta tcgctgataa gaaatacgga gaaatccttg gtgtacacat
     9181 tattggtcct gcagccgcag aattaataaa cgaagcatca agcatcatcg aaatggaaat
     9241 cactgttgag gaaatgctga agaccatcca cgggcaccca acttactctg aagtgatgta
     9301 cgaagcgttt gcagatgttc taggaatggc catccattca cctaagaaaa aataaaacga
     9361 agatagatta gactggaagg ttatttccag tctctatcat ataaagtaaa gggatatcat
     9421 gaaatacatt atcaatcatt caaatgacac tgcttttaat attgccttgg aagaatacgc
     9481 ctttaaacac cttttggatg aggatcaaat cttcctactt tggattaaca agccatctat
     9541 cattgttggt cgtcaccaga acactatcga agaaatcaac cgtgattatg ttcgcgaaaa
     9601 tggtattgag gtagttcgcc gtattagtgg tggtggagct gtttaccacg atttaaataa
     9661 cctcaactac acgatcatct ccaaagaaga tgaaaataag gcatttgact tcaagagctt
     9721 ctcaactccg gttatcaata ccctggctca acttggggtt aaagctgagt tcacaggtcg
     9781 taatgacctt gagattgatg gtaagaagtt ctgtggcaat gcccaagcct atatcaacgg
     9841 ccgtatcatg caccacggtt gcttgctctt tgacgttgat ttgtcagtcc tcgcaaatgc
     9901 ccttaaggtt tcaaaagata aatttgaatc aaaaggtgtg aaatccgtcc gtgcccgtgt
     9961 aaccaatatt atcaatgaat taccaaaaaa aatcacagtc gaaaaattcc gtgatttact
    10021 cctggaatac atgaaaaaag agtacccaga gatgactgaa tacgtctttt cagaagaaga
    10081 attggccgaa atcaatcaca tcaaggatac taagtttgga acttgggact ggaactatgg
    10141 taaatcacct gaatttaacg tccgtcgtgg aaccaaattc actagtggta aggttgaagt
    10201 ctttgctaac gttactgaat caaaaatcca agacatcaag atttatggtg acttctttgg
    10261 tattgaagac gttgctgcag tagaagatgt ccttcgtggg gtgaaatacg aacgcgaaga
    10321 tgttcttaag gcgctaaaaa ccattgatat cacacgctac ttcgctggta ttagccgtga
    10381 agaaatcgct gaagcggtag ttggataaat caaaaaaaga agttggccaa cttctttttt
    10441 tgatatttat ttacataatt taaaatacgt aaaatcataa actatctaga gcattctttt
    10501 gttcatcatt aacaatatgg gtatagaggt cagtgacttg tgtgctggca tgtcctagtt
    10561 ggtgactgac taaaacttgt gatttagtcg catcatagag cctagttgct agcgtatggc
    10621 gcagtttatg gggtgttaca cgcactttaa aatcctctga gtatttagca accattttct
    10681 caacgctaga agcatcgata cgattaggaa cacctctgta gagagttaaa aaaagggctg
    10741 tatctgtttt ttccgtttta tagcgttgat tccgaatggc cagataattc tctaaataag
    10801 gtttagcaaa agcagcgaca ttgactgagt cacgtttgcc accttttcga gtaacatcaa
    10861 taaccatcat ttttagattg agatctctta gatctagatt aacagcttca gataagcgaa
    10921 caccagatgc caagagaagg gcaataatgg ctaaatctcg ttctttattt ttgttgaatg
    10981 atgagagagc tcgatttgaa agctgttgtg ggtgctcttg atcgatataa gttagaaaac
    11041 cttctgtttc atcacctaga aagagttttt gcttgatatt ttcagctctg gcagcaaggg
    11101 tttctttctt tttcttggtt gaaacttttt tcattacatt acgatagaaa taaggttccc
    11161 cctgatcgtt ttcaacctcc tcggttagat acttgtaaag actagaaagt gctgataagg
    11221 ttcgattgat agttgtctgt gaaacacctt gttttgttgt attagcattc agcaagggac
    11281 gttcacgtag ataaaggata aaggattcca tgtctttctt agacatattt tccaaaactg
    11341 ataaaggaat atcggatatt ttatcagcgt ttgaaatacc agactccaaa acccagctga
    11401 aaaatcggtc atattcctta aggtattcgt acagggttgt aaaactgtag ggcacagcca
    11461 gcttagattg gtagtattcc agaacatacc agggcatgag ttgttttagt ttgtcgattc
    11521 gttccagtaa aatctcacgt ttcatgtatt ttctccataa gtaagtatac tagtagtata
    11581 gcatagactt gtatattttt caagaaaatt atagtttttc tgaaagatgt tataggagtt
    11641 tttcaaagtg ataaaaagac ttagacctac aaacaaaaca gaataaggaa aataataaaa
    11701 atctcaccca ctaaacttct gttaatacta cataactgaa gagctatata aggagctatg
    11761 agatacaaaa cacattgtat aatagattga aactagaata gtacatctga acttctaaaa
    11821 cattgctaga aattgatttg attgtcctga ttgttttatc ctatttctat ttcatttcac
    11881 tatataattg ctattgtttt ct
//
LOCUS       DBJKQU010000053        11868 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.053, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000053 DBJKQU010000000
VERSION     DBJKQU010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11868
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.053"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            113..382
                     /gene="blpJ"
                     /locus_tag="ACSUUC_001747"
     CDS             113..382
                     /gene="blpJ"
                     /locus_tag="ACSUUC_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HHQ8054914.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            451..681
                     /gene="blpU"
                     /locus_tag="ACSUUC_001748"
     CDS             451..681
                     /gene="blpU"
                     /locus_tag="ACSUUC_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HHQ8054915.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            684..803
                     /locus_tag="ACSUUC_001749"
     CDS             684..803
                     /locus_tag="ACSUUC_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HHQ8054916.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            1100..1261
                     /locus_tag="ACSUUC_001750"
     CDS             1100..1261
                     /locus_tag="ACSUUC_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054917.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIVYMIAVMIYF
                     SLIKKKEKK"
     gene            1284..1642
                     /locus_tag="ACSUUC_001751"
                     /pseudo
     CDS             1284..1642
                     /locus_tag="ACSUUC_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
     gene            2271..2654
                     /locus_tag="ACSUUC_001752"
     CDS             2271..2654
                     /locus_tag="ACSUUC_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HHQ8054918.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            2706..3395
                     /locus_tag="ACSUUC_001753"
     CDS             2706..3395
                     /locus_tag="ACSUUC_001753"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHQ8054919.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRELLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3437..3670
                     /gene="blpZ"
                     /locus_tag="ACSUUC_001754"
     CDS             3437..3670
                     /gene="blpZ"
                     /locus_tag="ACSUUC_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HHQ8054920.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            3821..4432
                     /locus_tag="ACSUUC_001755"
     CDS             3821..4432
                     /locus_tag="ACSUUC_001755"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHQ8054921.1"
                     /translation="MEFFDKFHALCFGFLVLIIVIIVPYTINHGDFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            4594..5388
                     /gene="ccrZ"
                     /locus_tag="ACSUUC_001756"
     CDS             4594..5388
                     /gene="ccrZ"
                     /locus_tag="ACSUUC_001756"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HHQ8054922.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5385..6020
                     /gene="trmB"
                     /locus_tag="ACSUUC_001757"
     CDS             5385..6020
                     /gene="trmB"
                     /locus_tag="ACSUUC_001757"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HHQ8054923.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6146..6625
                     /gene="rimP"
                     /locus_tag="ACSUUC_001758"
     CDS             6146..6625
                     /gene="rimP"
                     /locus_tag="ACSUUC_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HHQ8054924.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6669..7805
                     /gene="nusA"
                     /locus_tag="ACSUUC_001759"
     CDS             6669..7805
                     /gene="nusA"
                     /locus_tag="ACSUUC_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HHQ8054925.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7827..8120
                     /gene="rnpM"
                     /locus_tag="ACSUUC_001760"
                     /gene_synonym="ylxR"
     CDS             7827..8120
                     /gene="rnpM"
                     /locus_tag="ACSUUC_001760"
                     /gene_synonym="ylxR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase P modulator RnpM"
                     /protein_id="HHQ8054926.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8113..8412
                     /locus_tag="ACSUUC_001761"
     CDS             8113..8412
                     /locus_tag="ACSUUC_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HHQ8054927.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIEDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8429..11194
                     /gene="infB"
                     /locus_tag="ACSUUC_001762"
     CDS             8429..11194
                     /gene="infB"
                     /locus_tag="ACSUUC_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HHQ8054928.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAEPVAPKTEKVAAKPQSRNFK
                     AEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNRRFNDQAKKQ
                     QGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEERFKQYQAAKE
                     ALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKKQARPDKNRD
                     DYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTPKPVTERKFH
                     ELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGETIELLMVDYG
                     IEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTLLDTLRNSRV
                     ATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDITILVVAADDG
                     VMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTAWGGDSEFVE
                     ISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAVATLLVQQGT
                     LNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGDHFAVYEDEK
                     SARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADVQGSVEALSA
                     SLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQARQQAEADDVE
                     IRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIGGFMVINGKV
                     ARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDIKMDDVIEAY
                     VMEEIKR"
     gene            11445..11795
                     /gene="rbfA"
                     /locus_tag="ACSUUC_001763"
     CDS             11445..11795
                     /gene="rbfA"
                     /locus_tag="ACSUUC_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HHQ8054929.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3616 a         2077 c         2680 g         3495 t
ORIGIN      
        1 agtagacgta tatacttttt taagaaaatc aaaaagatac tataaaaaat ctatttgttt
       61 attgaattta agactttggt aacaaattga aaataaaaag gaggtattca tcatgaatac
      121 aaaaatgttg tcacagttag aggttatgga tactgaaatg cttgcgaaag ttgaaggggg
      181 gtatagctcc actgattgtc aaaatgcact gattacagga gtcactacgg gaattataac
      241 tggtggaact ggagcaggtt tggccacttt aggagtagct ggacttgctg gtgcatttgt
      301 tggagcacac attggtgcaa ttgggggtgg attaacatgc ttaggaggta tggttggtga
      361 taaattggga ctaagttggt aagacttata gtaaaattat gaggattcta ttctgattta
      421 ttttagtttt ttaaaaaagg agtatttgtc atggatacaa aaatgatgtc acaattttct
      481 gttatggata ctgaaatgct tgcttgcgtt gaaggtggcg gatgcaattg gggagatttt
      541 gccaaagcag gtgttggagg agcagcagca agaggtcttc aactaggcat taaaacagga
      601 acatggcaag gtgcagcaac tggtgctgcg ggtggagcta tacttggagg tgtagcctat
      661 gcagcaacat gttggtggta attatggatt ttaaaagttt tattattggt ttagtagttg
      721 gtatatttgg tccttatatg gataatttaa ttagaaaaat attttcaaaa tttcccaaaa
      781 aggatacaga tagtaccccc taaaaaataa atttctcccc tgtatttgct agcttaattt
      841 acaggggagt ttctttaata ttgtttcgcc tgtcaaaatg atatgtgata gcaggatgaa
      901 aagtctacaa acaagttggt atcaatacaa tataaagagg aaagtatgtt tttcatgctt
      961 gcttttttaa tttttacaat tcaagaggtt ttgatgacca tttatgattt gagtgatcca
     1021 aggtcaaaat aagtgctata ctagcagtgt aaatgttctt gctcaactaa gataaatcgc
     1081 acatttagga ggaaatctta tgaagaaaaa aatactgatt attttcgttc tgtatctaat
     1141 catgtccatc tttctatatc cgcttaggga gagtgcttgg tatcagctat tttataccat
     1201 agtctatatg attgcggtta tgatctattt ttctttaatt aaaaagaaag aaaagaaatg
     1261 aaagattttc ttgattaaaa agaatcatat tctttgtgag attgttcctg ggtcagttgc
     1321 ctttgcttgt ttctacttat ctatttctat ttcgtcagtt ttccaatttc ttttagtggt
     1381 tattaacttg acttctattt tggttactgt ttatcttact agggaaatga gattaagaga
     1441 gtttgaagat gatgatttgg ttagtcctag aaccaatcaa ctcatgttta tcggcttgac
     1501 aggctttatg tctattattt gtttgtatag agggatcaca gcaggagaat cctaccaaca
     1561 aataattgcc tacattggcg ctattctctg cttgaccatc atgcttctgc tcatttgggg
     1621 attgaagtat tataaaaagt agaggctaat gcagtttttg caatttaaga tgtcttgatg
     1681 acaattcaag atttggatga aaaactttga caaatagtgc tatactgaaa ttgtcaaagt
     1741 tgcaacgggt gctgctacat tatgttaaaa atcgctcttg attgataagc tggatttgtt
     1801 aggaaaggag taaataatta tggataagaa aaagatagtt tcgactataa tatgtatagt
     1861 atttcttgta gtgtcagtag ataatttttt tagagactta accccgttac tgttcatttt
     1921 aaatattatt ggtctgtctt gcttttcagt gctaacatac actaacataa aagagatact
     1981 cttaaatata agtaaatgat gatttggtta gtcctagaac caatcaactt atgtttatcg
     2041 gcttggcaga ttttatgttt gtcatttgtt tgtatagagg tatttcagaa acagaattct
     2101 atcaacaact aatcgtttat ataggtgtat tctctgcttg tttatcacgc ttctgctcat
     2161 gtggggcttg aagtattata aaaagtagct ttctatcctt ttctgacagg atatttgagt
     2221 agaaggctct attaaattgt tagtgaaata aatgaatgga ggtatttaat atgaaataca
     2281 gattattttt tgttattttc ttgagtagtg tgttggatat tcttttaggg acatttttac
     2341 aaatctctat cgtatctatt gggtggcttg ttctttacag tggtttgttt gaagcaggag
     2401 ttttccttct tgctaataaa ggggtggcgg taaaaatcaa ggaagtagat attcgaaatc
     2461 gctttaaatt tatttttgga aaaaccttat ggtttcaaat tcttttgctc atctttttga
     2521 taatcaaact ttatcttggt ttggatgcga ggttgatttt attctatgga catattttca
     2581 ttgtctttaa tgccttaatg tatctattat ctagtagtca ggttagcctt aaaaaaaaca
     2641 aactgtcttc ttaatcttac agcagtagag cctgacaagg tgaggtcata gtagggagga
     2701 tttctatgaa aaagtatcaa cttctattca aaataagtgc agtcttctct tacttatttt
     2761 tcgtatttgg tctttctcag ctgacgctta tcgtccaaaa ttattggcaa ttttcttccc
     2821 agattggtaa tttcgtctgg attcaaaata tcttgagttt actttttatt ggagtcatga
     2881 ttgtggttct tgttaagaca ggccatggtt atctcttccg cattccaaga aaaaaatggc
     2941 tttggtattc gattttgaca gtattagtgg tagtgttcca gatctctttt aacgttcaga
     3001 cagctaaaca tgttcagtca actgcggaag gttgggctgt attgattggt tatagtggga
     3061 ctaactttgc agagctaggt atttatatag ccctgttctt tctggttcca ctgatggaag
     3121 agttaatcta tagagaatta ctgcaacatg ctttctttaa gcattcgcga tttggtcttg
     3181 atttgcttct tccttctatt ttatttgctc tccctcattt ttcaagcctg cctagtctgt
     3241 tagatatctt cgtctttgca acagttggaa tcatctttgc tggtttgacc cgctatacca
     3301 agagcattta tccatcctat gcggtgcatg tgatcaataa tattgtagcg accttcccgt
     3361 ttttgctcac ttttctacat agggtcttgg ggtaaaaaaa caaaaggctt gcttttcagc
     3421 catagaggag gtcatcatgt ataaacactt atttttccta gattccaaaa ctttagatcg
     3481 gttgacaccc tatattctag tcttggcttc tgacaccatt gcttttaatg tttttgtgct
     3541 aacctttgta tctgcggtgg tttttaattt cctaaattcc atgctagctt taatggctat
     3601 attcataggg gctggctatg tggtcggatt ttggttacta atactcaatg aaaatcaaag
     3661 agcaaactag gaaactagcc gcaggctgta cttgagtacg gcaaggcgac gttgacgtgg
     3721 tttgaatttg attttcgaag agtataaaat ggtttgtttt ggaaaggcta gaactaaaga
     3781 atgacgtgta ggaagtctgt ttgttgagga ggataatttt atggagtttt ttgataaatt
     3841 tcatgccttg tgttttggat ttttagtact aataattgtc attatagttc cttatacgat
     3901 taaccatggg gatttttttc aaaatgaatc tgcattgatt cttgtaagtc ttcttgtaac
     3961 ctcgctgagt gttgcttatg ctagaaagtt tgaaatgatt tcttttggga tgttaagcaa
     4021 gaaacaactt ttgcttttca ttgcaatctt tcttctaagt gtacttgaga cgctggttta
     4081 tattcatttc ttcgctgttt cttctggctc aggggtccaa cacttggcgg aagtcagcag
     4141 aggaatttcc ctgtctttga ttttgactac ctcagttttt ggccccatcc aggaggaact
     4201 cattttcaga ggacttcttc aaggtgcggt ttttgacaat tcttggttag ggcttgtgct
     4261 aacttcctct ctcttttctt tcatgcatgg accttctaat gtcccttcgt ttatttttta
     4321 tctacttggg ggcttgttgc tgggccttgc ttataaaaag agccaaaact tatgggtttc
     4381 tactctagtc catatgcttt acaacagttg gccactctta tattatttat aaaaatcatg
     4441 aaaaggtaag taggagattg tgcttacctt tttctttcta taatgataac ccaaaccact
     4501 ccagaggctt ttctttgaga atcgggttag agtggttgac gaataggcca aaaactagta
     4561 gaatagtaag gaaactttat acggaggaaa gaaatggatt tgggtgataa tgagctaaca
     4621 ctgactccca tacctgggaa aagtggcaag gcttatatgg gtagctatcc tgatgggaag
     4681 cgcatctttg taaaaatgaa cacctctcca atcctacctg gtctagctag agaacaaatt
     4741 gctccacaat tattatggag tcgtcgtttg gcagatgggc gtgatatgtg tgctcaagaa
     4801 tggttgacag gcaagatatt gaccccctat gatatgaatc gtaagcaaat cgtcaatatt
     4861 ttaacccgtc ttcatcgctc acgtccgttg atgacacaat tgagtcgttt gggctatgcc
     4921 atggaaacac ctgtagattt actacagtct tggcaagaaa cggctccaga tgctttgcgt
     4981 aaaaatcatt ttatcagtga agtgatggct gatttacgtc agactattcc aggatttaga
     5041 gaggaccatg cgaccattgt ccatggagat gtacgacata gtaattggat tgagacagat
     5101 agtggcttga tttatttagt agattgggat tcggttcgct tgaccgatcg catgtttgat
     5161 gtggcccata tgctctgcca ttatatttca gaacatcagt ggaaggaatg gttgacctac
     5221 tacggttaca agtacaatca aacggtatta agtaaattgt attggtatgg tcaattgtct
     5281 tatttgagtc agatttccaa gtattatatg aaccaagatt tagaaaatgt caatcgggag
     5341 attcatggtt tgcgtcattt ccgagacaag tatggaaaga gaagatgaga gttagaaatc
     5401 gtaaaggggc aacagaatta ctagaggcaa atccccagta tgtggtcctc aatcccttgg
     5461 aagccaaggc aaaatggcgg gacttgtttg gcaatgataa tcccattcat gtggaagttg
     5521 gaagtggaaa gggtgccttt gtttcaggta tggccaagca aaaccctgac atcaactata
     5581 tcgggattga tattcaaaag tctgttttga gctacgcttt ggacaaggtg cttgaagttg
     5641 gagtgcctaa catcaagctc ttgtgggtag atggttctga cttgactgac tactttgaag
     5701 acggtgagat tgatcgcttg tatctgaact tttcagatcc atggccgaaa aaacgccatg
     5761 aaaagcgtcg tttgacctac aagacctttt tggatacctt caaacgtatc ttgcctgaaa
     5821 atggagaaat tcatttcaag acggataacc gtggcttgtt tgagtacagt ttagtgagct
     5881 tttctcaata tggcatgaaa ctcaatggtg tctggctaga tttgcatgcc agtgattttg
     5941 aaggcaatgt catgacagaa tacgagcaaa aattctcaaa caaggggcaa gttatctacc
     6001 gagttgaggc agaattttaa gagatagcct aaaattaggc tgtacaagtg cttttgcttt
     6061 acataagttg gcaaacgtgc tatactgata gtaagaatat gaaaagtgag gcggggaaat
     6121 atcttcgcct cttgcttatg aggaggtgga cgcaatcgca acaatcgtag aattagtcag
     6181 agaagttgta gaacctgtca tagaagctcc ttttgaactc gtggatatcg agtatggaaa
     6241 gattggcagt gacatgattc tcagtatttt tgtagataaa cccgaaggaa ttaccttgaa
     6301 cgacacggca gacttgacag aaatgatcag tcctgtccta gacaccatca agccagatcc
     6361 cttcccagaa caatatttcc tagaaattac cagtccaggt ttggaacgtc ctttgaaaac
     6421 caaggatgcc gtcgctggag cggttggaaa atacatccat gtcgggctct accaagccat
     6481 cgataagcaa aaggtctttg aaggaacctt gttggccttc gaagaggacg agttgactat
     6541 ggaatatatg gacaagacgc gtaagaaaac cgtccaaatt ccatacagtt tagtatcaaa
     6601 agcacgttta gcagttaaat tatagaaaaa gaaaggatag cttttgagga ttcaaaagtg
     6661 aagaaaacat gagtaaagaa atgctagagg ccttccgcat tttggaagaa gacaagggaa
     6721 tcaaaaaaga agatatcatc gacgcagtag tagagtcgct tcgttccgct tatcgcagac
     6781 gctatggtca gtcagacagc gtagctattg acttcaacga aaaaacaggt gactttacag
     6841 tttatactgt ccgtgaagtt gttgatgaag tatttgatag ccgtttggaa atcagcttga
     6901 aagatgctct tgccattaat tcagcttatg aacttggaga caaaatcaag tttgaagaag
     6961 caccagctga gtttggtcgt gtagcagccc aatctgccaa acaaaccatc atggaaaaaa
     7021 tgcgcaagca aacacgtgcc atcacttaca atacttacaa agaacatgag caagaaatca
     7081 tgtctggtac agtagaacgc tttgacaacc gctttatcta tgtcaacctt ggtagcatcg
     7141 aagcccaatt gtcaaaacaa gaccaaattc ctggagaagt ttttgcttct catgatcgta
     7201 tcgaagttta tgtttacaag gttgaagaca accctcgtgg tgtgaacgtc tttgttagcc
     7261 gtagccatcc agaaatgatc aaacgtttga tggagcaaga aattccagaa gtttatgatg
     7321 gaactgttga aatcatgagc gtggctcgtg aagcaggtga ccgtacgaag gttgctgttc
     7381 gtagccacaa tccaaacgtg gatgctatcg gtacaatcgt tggacgtggt ggtgctaata
     7441 tcaagaagat tactagcaaa ttccacccag ctcgttacga tgctaaaaat gaccgcatgg
     7501 taccaatcga agaaaatatc gatgttatcg agtgggtagc agatccagct gaatttatct
     7561 acaatgccat cgctcctgct gaggttgacc aagttatctt tgatgaaaac gacagcaaac
     7621 gtgccttggt ggttgttcca gataacaagc tttctcttgc cattggtcgt cgtggacaaa
     7681 acgtgcgctt ggcggctcac ttgactggtt accgtatcga tatcaagtct gctagcgaat
     7741 ttgaagccat ggaagacgct gcttcagtag agttggaagt agaaaacgat actgtagaag
     7801 aataaaagct gctagaggag ggaaagatga aaacaagaaa aatccctttg cgcaagtctg
     7861 ttgtgtctaa cgaagtgatt gataagcgtg atttgctccg cattgtcaag aacaaggaag
     7921 gacaagtctt tattgatcct acgggcaagg ccaatggccg cggcgcttat atcaaactag
     7981 acaatgcaga agccctagag gcgaaaaaga agaaggtctt taaccgcagc tttagcatgg
     8041 aagtggaaga aagcttttat gacgagttga tcgcttatgt ggatcacaaa gtgaaaagaa
     8101 gagagttggg acttgaataa gcaaaagata agtaatctct tggggcttgc tcagcgagca
     8161 gggcgcatca tatcgggtga agaattggtg gtcaaggcca ttcaagacgg caaggccaag
     8221 ttggtctttc tagctcatga tgctggaccc aatctgacca agaagattga agataaaagt
     8281 cattattatc aagtagaaat tgtaaccgtg ttttcaacac tggaattaag catagcagtc
     8341 gggaaatcga gaaaggtttt ggctgtaaca gatgctggat ttacaaagaa aatgaggtct
     8401 cttatggaat agaagaggag gacatgattt gtctaagaaa agattgtacg aaatcgcaaa
     8461 agaacttgga aaagaaagta aagaagttgt agcgcgtgca aaagagttgg gcttggatgt
     8521 gaaaagccac tcatcaagtg tggaagaagc tgtcgctgca aaaattgctg ccagctttaa
     8581 gcctgcagct gctccgaaag tagaagcaaa acctgcagca ccaaaagtaa gtgcagaaaa
     8641 gaaagccgaa aaatctgagc cagctaaacc agctgagcca gtcgctccga aaacagaaaa
     8701 agtagcggct aaaccgcaaa gtcgtaattt caaggctgag cgtgaagcac gtgctaaaga
     8761 gcaggcagag cgacgcaagc aaaataaggg caataaccgt gaccaacaac aaaacggaaa
     8821 ccgtcagaaa aacgacggcc gtaatggtgg aaaacaaggt caaagcaacc gcgacaatcg
     8881 tcgctttaat gaccaagcta agaagcagca aggtcagcaa aaacgtagaa atgagcgccg
     8941 tcagcaagag gataaacgtt caaatcaagc ggctccacgt attgacttta aagcccgtgc
     9001 agcagcccta aaagcagagc aaaatgcaga gtacgctcgt tcaagtgagg aacgcttcaa
     9061 gcagtatcag gctgctaaag aagccttggc tcaagctaac aaacgcaagg aaccagagga
     9121 aatctttgaa gaagcggcta agttagctga acaagcacag caagttcaag cagtggttga
     9181 agtcgtccct gagaaaaaag aacctgcagt ggatacacgt cgtaaaaaac aagctcgacc
     9241 agacaaaaat cgtgacgatt atgatcatga agaagatggt cctagaaaac aacaaaagaa
     9301 tcgaagtagt caaaatcaag tgagaaatca aaagaatagt aactggaata acaacaaaaa
     9361 gaacaaaaaa ggcaataaca agaacaaccg taatcagact ccaaaacctg ttacggagcg
     9421 taaattccat gaattgccaa cagaatttga atatacagat ggtatgaccg ttgcggaaat
     9481 cgcaaaacgt atcaaacgtg aaccagctga aatcgttaag aaacttttca tgatgggtgt
     9541 catggccaca caaaaccaat ccttggatgg ggaaacaatt gaactcctca tggtggatta
     9601 cggtatcgaa gccaaacaaa aggttgaagt ggataatgct gacatcgaac gtttctttgt
     9661 cgaagatggt tatctcaatg aagatgaatt ggttgagcgt ccaccagttg ttactatcat
     9721 gggacacgtt gaccacggta aaacaaccct tttggatact cttcgtaact cacgtgttgc
     9781 gacaggtgaa gcaggtggta ttactcagca tatcggtgcc taccaaatcg tggaaaatgg
     9841 taagaagatt accttccttg atacaccagg acacgcggcc tttacatcaa tgcgtgcgcg
     9901 tggtgcttct gttaccgata ttacgatctt ggtcgtagcg gcagatgacg gggttatgcc
     9961 tcagactatt gaagccatca accactcaaa agcagctaac gttccaatca tcgtagccat
    10021 taacaagatt gataaaccag gtgctaaccc agaacgcgtt atcggtgaat tggcagagca
    10081 tggtgtgatg tcaaccgctt ggggtggaga ttctgaattt gttgaaatct cagctaaatt
    10141 caaccaaaat atcgaagaat tgttggaaac agtccttctt gtagctgaaa tccaagaact
    10201 caaggcagac ccaacagtgc gtgcaatcgg tacggttatc gaagcgcgct tggataaagg
    10261 aaaaggtgcg gtcgcaaccc ttcttgtaca acaaggtacc ttgaatgttc aagacccaat
    10321 cgttgtcgga aataccttcg gtcgtgtccg tgctatgacc aacgaccttg gtcgtcgtgt
    10381 taaagttgct ggaccatcaa caccagtctc tatcacaggt ttgaacgaag caccgatggc
    10441 gggtgaccac tttgccgttt acgaggatga aaaatctgcg cgtgcagcag gtgaagagcg
    10501 tgccaaacgt gccctcatga aacaacgtca agctacccaa cgtgttagcc ttgaaaacct
    10561 ctttgatacc cttaaagctg gggaactcaa atctgttaat gttatcatca aggctgatgt
    10621 acaaggttct gttgaagccc tttctgcctc acttcaaaag attgacgtgg aaggtgtcaa
    10681 agtgactatc gtccactcag cggtcggtgc tatcaacgaa tcagacgtga cccttgccga
    10741 agcttcaaat gcctttatcg ttggtttcaa cgtacgccct acaccacaag ctcgtcaaca
    10801 agcagaagct gacgatgtgg aaatccgtct tcacagcatt atctacaagg ttatcgaaga
    10861 gatggaagaa gctatgaaag ggatgcttga tccagaattt gaagaaaaag ttattggtga
    10921 agcggttatc cgtgaaacct tcaaggtgtc taaagtggga actatcggtg gatttatggt
    10981 tatcaacggt aaggttgccc gtgactctaa agtccgtgtt atccgtgatg gtgtcgttat
    11041 ctatgatggt gaactcgcaa gcttgaaaca ctataaagac gacgttaagg aagttacaaa
    11101 cggccgtgaa ggtggattga tgatcgacgg ctacaatgat attaagatgg atgatgtgat
    11161 tgaggcgtat gtcatggaag aaatcaagag ataagatttt ttgctccttt cttaggtggt
    11221 gagggacgca agcaaaccga tggtttcatt gcttattttt gagcctaggg tctcaaaaat
    11281 cccctgtgat gggactgata aatcagttcc atcactttca ccacggcgaa agaagcagat
    11341 gacttcaaat tgaacttcgt ttcaatttaa actgaaaatc aagaagttta aaatagctag
    11401 gtctgctggc ctagcttttg gttcaaagta gagaaaggaa tatcatggca aatcatttcc
    11461 gtacagatcg tgtgggcatg gaaatcaagc gtgaagtcaa tgagattttg caaaagaaag
    11521 tccgtgatcc acgtgtccaa ggtgtgacca tcacagatgt tcagatgctg ggtgacttgt
    11581 ctgttgccaa ggtttattac accattttga gtaaccttgc ttcggataac caaaaagccc
    11641 aaatcgggct tgaaaaagca actggtacca tcaaacgtga acttggtcgc aatttgaaat
    11701 tgtacaaaat cccagatttg accttcgtca aagacgagtc catcgagtat ggaaacaaga
    11761 ttgacgagat gctacgcaat ctggataaga actaaagaag aggggttgcc cctctttttt
    11821 ggtggaggaa aataggttga atttgaaatg gaaaaatatt cttttaaa
//
LOCUS       DBJKQU010000054        11037 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.054, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000054 DBJKQU010000000
VERSION     DBJKQU010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11037
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.054"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            1..386
                     /locus_tag="ACSUUC_001764"
                     /pseudo
     CDS             1..386
                     /locus_tag="ACSUUC_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            921..1613
                     /locus_tag="ACSUUC_001765"
     CDS             921..1613
                     /locus_tag="ACSUUC_001765"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HHQ8054930.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1666..4077
                     /locus_tag="ACSUUC_001766"
     CDS             1666..4077
                     /locus_tag="ACSUUC_001766"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HHQ8054931.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGRI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDEKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4327..5028
                     /locus_tag="ACSUUC_001767"
     CDS             4327..5028
                     /locus_tag="ACSUUC_001767"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054932.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5030..7738
                     /locus_tag="ACSUUC_001768"
     CDS             5030..7738
                     /locus_tag="ACSUUC_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHQ8054933.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALTTHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLRLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     YKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVVAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7834..8325)
                     /gene="tpx"
                     /locus_tag="ACSUUC_001769"
     CDS             complement(7834..8325)
                     /gene="tpx"
                     /locus_tag="ACSUUC_001769"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HHQ8054934.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8448..9377)
                     /gene="psaA"
                     /locus_tag="ACSUUC_001770"
     CDS             complement(8448..9377)
                     /gene="psaA"
                     /locus_tag="ACSUUC_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HHQ8054935.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEANLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9409..10257)
                     /locus_tag="ACSUUC_001771"
     CDS             complement(9409..10257)
                     /locus_tag="ACSUUC_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HHQ8054936.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10254..10976)
                     /locus_tag="ACSUUC_001772"
     CDS             complement(10254..10976)
                     /locus_tag="ACSUUC_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HHQ8054937.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3225 a         2057 c         2524 g         3231 t
ORIGIN      
        1 ataaaattaa aaagacttgc tttaattagt ggtatcgtcg gtcttgtggg aggaatttta
       61 cttcttattg gtccttttgt cttgttggga atagcggtaa acacagctgc tacaactctt
      121 aatggaggag ctactgcagg ggctttttca ggtgtagcct tactcttgaa tgccttgaag
      181 attgcaaatc ttgttcttgg tatcattgct attgtttact ataaaggaga taagcgtgta
      241 ggtgcagctc cgtctgtact aatgattgtt tctggtggag ttagtctcat tctattccgt
      301 tcttaggatg ggttgggggg atttttgcta ttatcggagg atctctattc ctttcaacat
      361 tgaagaaatt caaatcagaa gaataaaagg tattttagca tgaaaagaac aaaaaagttt
      421 atcggtatag gagtagctct attatctctt tctcttctag ttgcatgtgg aacataaagt
      481 tcaaagaata cttcaacaag taatgatgag aagacagtag caacatccaa tagttcaaaa
      541 gaaacaatca ctttcgatac accggttgta acagacgatg cgattgaatc aatacgcact
      601 tatgcagatt atatagatct ttataaaaat atttttgatg attattttac taaagctgag
      661 gaaggtttca aaggcatagc tatggaaaat aatgactcgt ttactaaact aaaagagtca
      721 actcaaaaat tattcgatgc gcagaaaaaa aggttaaata atgaagatag aatagaaaca
      781 accaaaaaca atgtgattgc caaacattgt caaacagtcc tttccttttt ggttttgact
      841 agcttttttg tgaaaaattg tgtaaaatag aatagataaa cgaggggaaa cctcggaaaa
      901 tttaaaggag aatccatcta atggtaaaat tggtttttgc tcgccacggt gagtctgaat
      961 ggaacaaagc taaccttttc actggttggg ctgatgttga tttgtctgaa aaaggtacac
     1021 aacaagcgat tgacgctggt aaattgatca aagaagctgg tatcgaattt gaccaagctt
     1081 acacttcagt attgaaacgt gctatcaaaa caactaactt ggctcttgaa gcttctgacc
     1141 aattatgggt tccagttgaa aaatcatggc gcttgaacga acgtcactac ggtggtttga
     1201 ctggtaaaaa caaagctgaa gctgctgaac aatttggtga tgagcaagtt cacatctggc
     1261 gtcgttcata cgatgtattg cctccaaata tggaccgtga tgatgagcac tcagctcaca
     1321 cagaccgtcg ttatgcttca cttgacgact cagtaatccc agatgctgaa aacttgaaag
     1381 tgactttgga acgtgctctt ccattctggg aagataaaat cgctccagct cttaaagatg
     1441 gtaaaaacgt attcgtagga gctcacggta actcaatccg tgcccttgta aaacacatca
     1501 aaggtttgtc agatgatgag atcatggacg tggaaatccc taacttccca ccattggtat
     1561 tcgaattcga cgaaaaattg aacgttgttt ctgaatacta ccttggaaaa taaaaaattg
     1621 taagcctagg attgatttct aggcttttta tgttagtatg gaagtatgat aaggaataaa
     1681 aaacaagatt atgtactggc ctacaaacaa ccagcttcaa ccacttacat gggttgggaa
     1741 gaagaagctt taccgatagg taatggttct ttaggagcaa aagtatttgg ccgtataggg
     1801 gctgaacgga ttcaatttaa tgaaaaaagt ctctggtctg gaggtccact tcctgatagt
     1861 tcagattatc agggtggaaa tcttcaggat cagtatgttt ttttagctga gattcggcag
     1921 gctttggaga agagagatta caatctggct aaggaactgg ctgagcagca cctaattggg
     1981 ccaaaaacga gtcaatatgg gacctatctg tcttttgggg atattcacat tgagttcagc
     2041 cagcaaggta cgactttgtc tcaggtgacg gactatcaga gacagctgaa tattagtaag
     2101 gcacttgtga cgacttctta tgtctataag ggaacgcgat ttgaacgtga agcttttgcg
     2161 agttttccag atgatctctt ggttcagcgt tttactaagg aaggggcgga aactctagat
     2221 tttactatag aactatcctt gacctgtgat ttggcttctg atgaaaagta tgagcaggaa
     2281 aaatctgatt acaaggagtg taagttggat attactgatt ctcatatctt gatgaaggga
     2341 agagttaagg ataatgatct gcggtttgct agttatctag cttgggaaac ggatggagat
     2401 attagagttt ggtcagatag ggttcagata tcaggagcca gttatgccaa tctcttcttg
     2461 gccgctaaga cggattttgc ccaaaatcct gctagcaatt atcgcaagaa actagattta
     2521 gagcaacagg tgatagactt ggtggacaca gctaaagaaa agggctatac ccaattgaaa
     2581 tcaaggcata tcgaggacta ccaagcctta ttccagcgtg ttcaattgga tttggaagct
     2641 gatgttgacg catccactac agatgatttg ttaaaaaatt ataagccaca agaagggcag
     2701 gctttggagg agctgttctt ccagtatgga cggtatttat tgattagttc gtccagagac
     2761 tgcccagatg ctctaccagc taacctacag ggagtctgga atgcggtcga caatcctcct
     2821 tggaattcgg actatcactt aaatgtcaat ctgcagatga attattggcc agcctatgtt
     2881 accaatctcc tagaggcggt ctttccggtc atcaactatg tagatgattt gcgtgtctat
     2941 ggtcgtctag cggctgtaaa gtatgcagga atcgtctctc agaaaggtga ggaaaatggt
     3001 tggttggttc atactcaagc gactcccttt ggttggacgg cacctggttg ggattactat
     3061 tggggttggt caccagctgc caatgcgtgg atgatgcaaa ccgtttatga agcctattca
     3121 ttttataggg accaagacta tctcagggag aaaatttatc ccatgttgag ggaaacggtt
     3181 cgtttttgga atgccttttt acataaggat cagcaggcgc agcgttgggt gtcttctccg
     3241 tcttattctc cagaacatgg gccgatttcg attggcaata cctatgacca atctctgatt
     3301 tggcagttat ttcatgattt tattcaggct gctcaggaat tgggactgga tgaggacttg
     3361 ttgactgagg ttaaggagaa gtctgattta ctaaatcctt tgcaaatcac tcaatctggt
     3421 cgaatcaggg agtggtatga ggaggaagag cagtattttc aaaatgagaa agtggaggcc
     3481 cagcaccggc acgcttccca tctagtggga ctctatcctg gcaatctctt tagctacaag
     3541 ggacaagagt atattgaagc ggcgcgtgct agcctcaatg atcgtggaga tggcggcaca
     3601 ggctggtcca aggctaataa gatcaatctc tgggcgcgtt tgggagatgg caatcgcgcc
     3661 cataaattat tggcagagca gttaaagaca tccaccttgc caaatctttg gtgtagccat
     3721 cctccttttc agatagatgg taattttggt gctactagtg gcatggcaga aatgttactc
     3781 cagtctcatg cagcttatct ggtacctcta gctgccctac ctgatgcttg gtcaacaggt
     3841 tctgtttcag gcttaatggc acgtggacat tttgaagtga gcatgagctg ggaagataaa
     3901 aaactcttac agttgaccat tttatcaagg agcggaggag atttgcgagt ttcttatcca
     3961 gatattgaga agagtgtgat taaaatgaat caagaaaaaa taaaagcgaa atgcatgggg
     4021 aaagattgta tttcggtggc aacagcagaa ggtgatcttg ttcaatttta tttttaagaa
     4081 gatgttataa ggcagtaatt tgaaactgcc ttttaataag gatttaagaa tataagcagt
     4141 tttcaactag ttgaaaaagc gttataatga taataggaag taatactcaa tgaaaatcaa
     4201 agagcacaaa caaggaagct agccgcaggt tgctcaaaac agtgttttga ggttgcagat
     4261 ggaagctgac gtggtttgaa gagagatttt cgaggagtat aatttgtttg atagagggtg
     4321 ggtctgatgg cttatattga gatgaaacac tgttacaagc gttatcaggt tggggacacg
     4381 gagattgtgg ctaatcgtga tgtgaatttt gagattgaaa agggggagct ggttattatc
     4441 cttggtgctt caggtgcagg caagtcaaca gttcttaacc ttcttggggg aatggatacc
     4501 aatgatgaag gggaaatctg gattgatggt gttaatattg cggattatag ttcccaccag
     4561 cgcaccaatt accgtagaaa tgatgtgggg tttgtttttc agttttataa tctagtttct
     4621 aatctgacag ctaaggaaaa tgtggaactg gcttctgaaa ttgtgacaga tgccttgaat
     4681 cctgatcagg tcttgacaga tgtaggtctg gctcatcgtc taaataactt tccagcccag
     4741 ctttctggag gggagcaaca gcgagtctcc attgcacgcg cggtagccaa aaatcctaaa
     4801 attctccttt gtgatgaacc gactggagcc ttggattatc agacgggcaa gcaggttttg
     4861 aaaattctcc aagacatgtc tcgtcaaaag ggagcgacgg tgatcattgt gactcataat
     4921 ggagctttgg cgcccattgc tgatcgcgtg attcatatgc acgatgccag tgtcaaggat
     4981 gtggtgctca accagcatcc tcaggatatt gacagtttgg agtactagca tgatcaagcg
     5041 aaaaacttat tggaaggact taattcagtc cttcacaggc tccaaggggc gttttttatc
     5101 catcttgatc ctgatgatgt tgggatctct agccttagta ggcctcaaag taaccagtcc
     5161 caacatggag gcgacagcta atgcttattt aacaactgct caaaccttag atttggcagt
     5221 catgtctaac tatggcttgg atcaagcaga ccaagaagaa ctaaaacaga cggagggcgc
     5281 agaggtcgag tttggctatt tgacagatgt gactatggat aatgggcagg atgccattcg
     5341 gctgtactcc aaaccagagc gaatttcaac ctttcagcta agaaagggac gacttcctca
     5401 gtcagacaag gaaatcgctt tgaccactca tttgcaaggc caatacagcg tgggacagga
     5461 gattagtttt aaagaaaaag aagagggtca ttcctcttta aaagaccata cttataccat
     5521 tactggtttt gtggattcgg ctgaaatcct ctcccagcga gatatgggct acgcaggaag
     5581 tggaagtggg actctgacag cctatggggt gattttacct agtcaatttg atcagaaagt
     5641 ctacaatata gctcgtttga aatatcaaga tttagcaggt ttaaatgcct tttcatcagc
     5701 ttatgaagaa aaatccaagc aacatcagga agagcttgaa caaattttat cagataatgg
     5761 caaggtacgt ctgcgacttt tgaaaaaaga aggacaagag tctctagaca aggggcaaga
     5821 gacccttgac aaggctcaga ctaatttgca ggaaggcaag cgtcgtttag cagctgctca
     5881 agctcgtata caggctcaag aaagtcaact agccttgttt cctcaagctc agagagagca
     5941 ggctagtgct caacttaccc aagccaagca ggaattgggc aaggaagagg acaaactaaa
     6001 gcaagctgaa caaaatctag cccaagaaaa ggaaaaatta gaaaaacatc agcaagtctt
     6061 ggatgatttg gcggagccaa ggtatcaggt ttataatcgt cagaccatgc caggtggtca
     6121 gggctatctt atgtatagca atgcttcatc cagtattcga gcagtgggca atatctttcc
     6181 tgtggtactt tatgccgtag cagccatggt gacctttacg accatgactc gctttgtaga
     6241 cgaagagcga actcatgcag ggatttttaa ggccttgggt tatcgtagta aggatattat
     6301 cgccaagttt ctcctttatg gactagtagc tgggactgtc ggaacggctc taggtagtat
     6361 acttggtcat tatttgctag ccagtgtaat ttcaagtgtc attacaaaag gcatggtggt
     6421 gggagaaact cagattcagt tctattggac ctatagctta ctagcttttg tcttgagctt
     6481 gttggcgagt gtgttaccag cctatctggt ggcttggagg gaacttcatg acgaagcagc
     6541 ccagcttcta cttcctaaac ctcctgtcaa aggagctaaa atcttattgg agcgtatcgg
     6601 ttttatctgg cgtcgtctca gttttactca taaggtaaca gcccgcaaca tctttcgtta
     6661 taagcagaga atgttgatga caatctttgg tgtggcaggt tctgtagctc tgctctttgc
     6721 aggtttggga atccaatctt ctgtagcagg agttccgtct aaacagtttc aacaaatcca
     6781 acagtatcag atgcttgtct ctgaaaatcc tagtgcgacc aatcaggaca aggtagagct
     6841 agcagaagtg ttgaaagggc aggagatact agcctaccag aaaatctatt ctaaagcgct
     6901 atacaaggat ttcaaaggca aagctggtct tcaaaacatt actcttatga tgatagagaa
     6961 ggaagatttg actcccttta tccatcttca acatcatcag caggagctga cattaaaaga
     7021 tggcatcgtt attacagcta aactcgccca gctggcaggt gtcaaggttg ggcagacttt
     7081 agaaattgaa ggtaaggaac taaaggtcgt tgctattact gagaactacg ttggtcactt
     7141 tatttatatg agtcaggcta gctatgagca actttacgga cagctacccc aagccaacac
     7201 ttatctggtc tcattaaggg ataccagtgc aactagtatc gaaagtcagg cgggcttgct
     7261 tatgaatcaa tctgcggtgt ccagcgttgt ccaaaatgct tcagccattc gactcttcga
     7321 ctctatcgct agctcactca atcagaccat gaccatcttg gtcatcgtat cggttctatt
     7381 agctattgtc atcctttaca atctgaccaa tatcaacgta gctgagagaa tccgtgaact
     7441 ctccactatc aaggttcttg gttttcataa taatgaagtc accctctaca tttaccgtga
     7501 gacgattgtg ctgtcccttg tgggaatcgt acttggtctg atagctggtt tctatttaca
     7561 ccaatttttg attcaaatga tttcgcctgc gactattctc ttttatccgc aggtaggctg
     7621 ggaagtctat gtaatcccag tggcagcagt aagcatcatt ttgaccttgc ttggtttctt
     7681 cgtcaattat tatctgagaa aggttgatat gttagaagcc ctgaaatctg tagagtaagg
     7741 tagttatttt tagctgattg aacttctatt tactaatatt caaaaatcct ccgtttcaaa
     7801 gagcagggaa ctctttgtga cagaggattt tttctatagg gctttagcag ctgcaattgc
     7861 ggcttcgaag tttggctcag aattgatatt atccacgtat tcaacgtagc gaatcgtatt
     7921 gtcagtatcg aggacaaaga ctgcgcgtgc taataggtgc cattcgttga tcaagagggc
     7981 ataatcgcgc ccgaaagaat ggtcaaagta gtctgaaagc ataatggcat tgtcaaggcc
     8041 ttcagcaccg caccaacgtt tttgagcaaa aggtaggtcc attgaaacag tcaatacgac
     8101 cgtgttgtcc agtccagcca attcttcatt aaaacgacgt gtttgagttg agcagatgcc
     8161 tgtatcgata gaaggaacga cactcaagac ttttttcttg ccatcaaaat cagccagaga
     8221 ttttttagaa agatctgttg tagtaagaga aaaatcaagc gccttgtcgc cgacttgtag
     8281 ttgtttacct gtaaagctca caggatttcc gagaaaagtt accataggat actccaatct
     8341 tttttcttcc attttagctg aaacagtcgg aattttccaa tgatttgacc ggaaatatgg
     8401 gcatagaaaa aacgccagct catgtgagaa tgacgttttt cataggttta ttttgccaat
     8461 ccttcagcaa tcttgtcaag gttgtatttc atcatgctgt agtagctgtc gccttcttta
     8521 ccttgttctg cgatagagtc agtaaagatt tgagcgtaga ttgggatgtt tgtgtcttga
     8581 gaaacagttt tcattggacg gtcatccaca cttgattcta caaagagtga tggaactttt
     8641 gtttggcgaa gtttttcaac caaggtcttg atttgttcag gagttccttc ttcttcagta
     8701 ttgatttccc agatgtaagc acttgggaca ccataggctt tagagaagta tttgaatgct
     8761 ccttcgctgg ttacaatgag tttcttttca gcagggatct tattaaattt atccttactt
     8821 tctttatcaa gtttgtctaa cttatcagta tattctttga gatttttttc atagaattct
     8881 ttattgttag ggtctttggc gctcaattgt ttggcgatat ttttagcaaa aataataccg
     8941 ttttcaaggt taagccaagc gtgtgggtct tcttttcctt tttcattttg accttcaagg
     9001 tagataacat caacgccgtc gctgactgcg aagtagtctt tgttttcagt tttcttggca
     9061 ttttctacca attttgtaaa ccaagcattg ccacctgttt caaggttgat accgttatag
     9121 aaaatcaaat tagcctcaga agttttctta acgtcttcag gaagtggttc gtattcgtgt
     9181 gggtcttgcc caatcggaac gatactatga aggtcaattt tgtcaccagc aatattttta
     9241 gtaatatcag cgatgattga gtttgtagca acaactttta gtttttgacc agaagttgta
     9301 tctttttttc cgctagcaca tgctacaaga atgattgcag aaagaaagag aacgagtaat
     9361 gtacctaatt ttttcattag atcctccaat ttattagggc tttgcccctt attttaacaa
     9421 atgtttattt ttcagtttca aatatcgttg tttgggagcg ataaagaagc taatgagaaa
     9481 gaaactagca gctgtaagca cgatactaga acctgccgca acattaaaac tatagccaat
     9541 aaagagtccc aaaactgaag cagtagctcc gaaggttgag gaaaggaaaa tcatactttt
     9601 cagactatta gcatacagat aagcagttgc agctggggta atcagcatgg ctacaatcag
     9661 gatagttccg acactttgca tggctgtcac agacacgaga gtcaggagta ccatgagaag
     9721 gtagtgatag aaattgacag gcattcccat ggctttagcc aagagttcat caaaggaagt
     9781 tatcaagagt tgcttgaaga aaatccagat taacaagagg atagctgccc ccacacccat
     9841 agtaataaac atatccgtat cttggacggc caggatatta ccaaaaagga tatggaaaag
     9901 gtcagttgaa cttttagcga caccaatcaa gatgataccg agggctaaga aagaagaaaa
     9961 ggtaatgccg atggcggtat cgcttttgat aatcgagttt cctttgatgt aggtaatgat
    10021 gatggcagct agcaatccaa agacaatggc tccgataaag aagtcaaggc ccaagatgaa
    10081 ggatagggct acacctggta agacagcatg tgaaatggca tctcccatga gtgacatccc
    10141 gcgtagaata atgaaacatc ccacagctcc agctacaatc ccgacgacaa tagctgttat
    10201 caaggcattt tgtaggaaat ggaatttttg caatccatcg ataaattctg caatcatagg
    10261 tcacctccat tgaaaaagag ttgattaccg taagcttctt ttagattggt ttcggtaaaa
    10321 gtttcttttg ttggaccaaa ggcaatcact tctcgattga caagtaagac ttgatcgaag
    10381 tagtggggaa tcttgctgag gtcgtggtga acgatgagaa ccgtcttccc agcttttttc
    10441 aaatctctca gcgtattcat gatgatttcc tcactgacag agtcaatccc agcaaagggt
    10501 tcatccaaga ggatatagtc ggcttcctgc accaaacatc tggcaatcaa gacccgctgg
    10561 aattgacctc cagacagttg actaatttga cgttcagcgt agtcagctag gccgacgatt
    10621 tcaagggcct cttgcacttt cttccaatgt ttagccttta aacttcgaaa gagaggaata
    10681 gagggaaata gtcctaacga gacgcattcc ttgaccttga tgggaaagtt gtagtcgata
    10741 ttgatttttt gttcgacata ggcaattcgg tgtaaggatt ttttaacttc cttgtcatcg
    10801 agaaatgcct gaccttgatg tgggataatt cccaacatac cttttaatag tgttgatttc
    10861 ccagcgccgt ttggaccaat gatgccggta attgttggtc catggagcac tagtgaaata
    10921 tccttaagtg ccaacgtttc tttgtaggag acactgaggt tttcgatacg tatcataaac
    10981 ttatattcct cctgtctctt aatatacatt aaaaaaaaaa ttaagtcaag ttaattt
//
LOCUS       DBJKQU010000055        10824 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.055, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000055 DBJKQU010000000
VERSION     DBJKQU010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10824
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.055"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            118..282
                     /locus_tag="ACSUUC_001773"
     CDS             118..282
                     /locus_tag="ACSUUC_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HHQ8054938.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            366..932
                     /gene="amaP"
                     /locus_tag="ACSUUC_001774"
     CDS             366..932
                     /gene="amaP"
                     /locus_tag="ACSUUC_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HHQ8054939.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            944..1114
                     /locus_tag="ACSUUC_001775"
     CDS             944..1114
                     /locus_tag="ACSUUC_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HHQ8054940.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1153..1761
                     /locus_tag="ACSUUC_001776"
     CDS             1153..1761
                     /locus_tag="ACSUUC_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HHQ8054941.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1792..1995
                     /locus_tag="ACSUUC_001777"
     CDS             1792..1995
                     /locus_tag="ACSUUC_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HHQ8054942.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2088..2360)
                     /locus_tag="ACSUUC_001778"
                     /pseudo
     CDS             complement(2088..2360)
                     /locus_tag="ACSUUC_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2567..2848
                     /locus_tag="ACSUUC_001779"
                     /pseudo
     CDS             2567..2848
                     /locus_tag="ACSUUC_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029691456.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(3129..3899)
                     /locus_tag="ACSUUC_001780"
     CDS             complement(3129..3899)
                     /locus_tag="ACSUUC_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HHQ8054943.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLYQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3914..4762)
                     /locus_tag="ACSUUC_001781"
     CDS             complement(3914..4762)
                     /locus_tag="ACSUUC_001781"
                     /EC_number="1.8.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016670 - oxidoreductase activity, acting
                     on a sulfur group of donors, oxygen as acceptor [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HHQ8054944.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4759..6234)
                     /locus_tag="ACSUUC_001782"
     CDS             complement(4759..6234)
                     /locus_tag="ACSUUC_001782"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HHQ8054945.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHTLGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6558..7914)
                     /locus_tag="ACSUUC_001783"
                     /pseudo
     CDS             complement(6558..7914)
                     /locus_tag="ACSUUC_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(7924..8241)
                     /locus_tag="ACSUUC_001784"
     CDS             complement(7924..8241)
                     /locus_tag="ACSUUC_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHQ8054946.1"
                     /translation="MNESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8258..8575)
                     /locus_tag="ACSUUC_001785"
     CDS             complement(8258..8575)
                     /locus_tag="ACSUUC_001785"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHQ8054947.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8590..9486)
                     /locus_tag="ACSUUC_001786"
     CDS             complement(8590..9486)
                     /locus_tag="ACSUUC_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HHQ8054948.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKTVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9489..10751)
                     /locus_tag="ACSUUC_001787"
     CDS             complement(9489..10751)
                     /locus_tag="ACSUUC_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHQ8054949.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQGALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPSWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         3730 a         2182 c         1670 g         3242 t
ORIGIN      
        1 aaagaaattg attttttgat attaaaataa aaaaggaggg taggcagtgt tgtgatcaat
       61 tattgctgga ggtcttattg gtctcttggc aggtaaaatc actaaaaaag tagttctatg
      121 ggaatcatcg caaatgtatt cgctggttta gtcggggcat atgcaggaca atctctttta
      181 ggtagttggg gtccatcaat cgctggaatg gctttgctcc catctattgt aggtgcagcg
      241 attgtgatta ctgtagtgtc attctttaca ggtagaaagt aaacttttcg ccagtaaagt
      301 tagcaaacta tttttaaatc aatgacggga aaaatagttt aaatgttaaa tcgaaaggat
      361 tgtatatgtc aaaagcaaag aaaatatgtt tcattatttt ctgtatttta atcttgacaa
      421 ttttccttcc tgttttgata gattatcatc aagttagtga tctaggtatt catctactga
      481 gctggagaca gaactccgta gttgaattct atcttgctag atatgtcttt tgggggacag
      541 tggttctatc aactttagtt ttattatcca ttttagttgt gatgttttat cctaaacgtt
      601 acttggaaat ccaacttgaa actaaaaacg atacattaaa attaaagaat tcggcaatcg
      661 aaggttttgt tagaagtttg gtgagtgatc atagattgat caagaaccca actgttcatg
      721 taaatttacg aaaaaataaa tgtttcgttc atgtagaagg taaaattctt ccttcagaca
      781 acatcgctga cagatgccaa ataattcaaa atgaaataac taatggattg aagcagtttt
      841 ttggtattga gcgtcaagta aaacttgaag ttgcagtaaa aaattaccaa ccaaaacctc
      901 aaaacaaaaa gactgttagt cgtgtgaagt aaggaagtaa aaaatggaat ggcttaaaca
      961 atatcgatat ccaattatcg ctggtctcat aggcgtattt ctggcttgtt tgattgtctc
     1021 ctttggcttc ttcaaaacaa tatttgtatt gattttagga gcactgggag ttgcagctgg
     1081 attatatatc gaaaaaaact atatagataa ataaaaaaat aaaaattact aatttaatta
     1141 aaggagtttc atatgtcaaa cgaaaaaaac acaaacacta acgtagaaaa gaaagatgct
     1201 actgttgtag ctcacgaaat caaaggggaa cttacttacg aagataaagt tatccaaaaa
     1261 atcattggtc tttcactaga aaacgtttca ggtcttttgg gaatcgatgg tggtttcttc
     1321 tcaaatctta aagaaaaaat cgttaacagc gatgacgtaa caagtggtgt taacgtagaa
     1381 gttggtaaaa cacaagttgc agttgactta aacgttattg ttgagtacca aaaaaatgtt
     1441 ccagctttat attcagaaat cagagaaatc gtatcttcag aagttgctaa aatgactgac
     1501 ttggaaattg ttgaaatcaa cgtaaacgtt gtcgacatca aaactaaaga acagcatgaa
     1561 gcagactcag taagccttca agatcgcgta tctgacgttg ctgaatcaac aggagaattc
     1621 acttcagaac aattcgaaaa agctaaatct ggtcttggat ctggtttctc aactgttcaa
     1681 gaaaaagtta gcgaaggtgt agaagctgtt aaaggtgcag caaatggtgt agtatctcac
     1741 gaaaacactc gtgtaaacta agataaaata aatataacag gagaaattat catgtcagta
     1801 gaagaaaaat taaatcaagc taaaggttct attaaagaag gtgttgggaa agccatcggt
     1861 gatgaaaaaa tggaaaaaga aggagcagct gaaaaagttg tttctaaagt aaaagaagtt
     1921 gccgaagacg ctaaagacgc tgtagaaggt gctgtagaag gtgttaaaaa catgttgagt
     1981 ggcgacgata aataaggtta ttggtaacat tagtcaaaag agtctgagtc aagatgattc
     2041 tcagaaaaca aaaagctaga gattcccaat tgcggaactc tagcttttta attttgcctc
     2101 tttctcttat tatatttcag caggttgttg gccatgagta tgaatcccat gtcaattctc
     2161 acttgacgct tacctctcag atgacatctc ttataaccca aacaaacctt tatctgccca
     2221 aagacagatt tcatatcaat cttacgttta gcgaaaattt gtctaccctt ggaagataaa
     2281 agtgcctgat attctttagt ttttaaacac tggtaacgtt cattcatata cagtcccttt
     2341 tgaggggctg attcaggttc ataatcgcag tcaacattga tttcaaggct gtttgctttc
     2401 tatctcccct ttttcatgat atattttcgt acaggttctt caatagtttc tatagtaaaa
     2461 tgaaccaaaa atagtacacg ttgcggtata atgttcttgt ggcatattca ttagattttc
     2521 gtaaacagtt ctctcctatt tgtgagcgaa caagtatagt caattgattg tcagtttgaa
     2581 gaccaagagt cgtaaggcaa aggatatggc agaatccatc caagggtggc tggcacaatt
     2641 tctagtgaac ctctttaaat ctattacgtt tgactgtgga aaagagtttt caaaatggaa
     2701 agatatttcc aatcatcacg atagtgagag cttttttgcg aatctaggat gttcaagaca
     2761 gcggcgtctc aacgaacatt caaatagact tttaaggtgt catgacttgc caaagcagac
     2821 agatttcaac gaagtcagtc aagaatttta ggctggacaa aaactcaatt tcaggagaaa
     2881 atgaaataaa tattcccaca ataaaacgca tagtatcaaa gtttttccaa cacctgatat
     2941 tatgcatttt ttaattttaa agactttttc ccagcctcaa gaaatcacat cccacctaaa
     3001 tcctttggat accaaatacc tcatcaggta ttttctgagt tggtaagact gtctagctta
     3061 atttgacaaa tggagggcgt taaatccagt ttttacagga agtctattta aatattttca
     3121 cactgacctt acaaaatatg aaataaatta tataaagtca ttcccatgac aaagaataac
     3181 atccctttaa aacagtatct tacccaattt tcaggtaaga cttttgatac aaccgtcccc
     3241 aatacccctc cgcatataga agcaagaaaa ataactggaa caggtgctaa atgatactga
     3301 tttaaacctg taaccacaac aattgtagcc aaatgagaca gctgggaaaa gaaaataatt
     3361 gcaagagaat acatcgttgc ttcttttatc gaaatagaaa aaaacaccat caataaagat
     3421 acattgagcg gaccaccacc aatccctaaa aaactagaaa ttaagcccaa tagaagacca
     3481 caaatcatat agaatcctat cttatcaaat tgataagttt ttttaaaatc tgttaaaaca
     3541 aatgatacaa gtaacatcac aaatagtaaa atcatttgaa caatagatac tagccgtact
     3601 gataattgat ataacaaaac ttgaaaaata agatgaccta gaaatcctcc taaaacagaa
     3661 gaaaaggata ccgtaaaaat caatctccat tttatctctt tactttgtga aaatcttttg
     3721 attgttgaaa taatcgccat tataaaaaca gagaaactag aataaaaagc aatatcactg
     3781 accgaatggt atccaaaact atccataagt ggcttaatta taattccacc acccatgcct
     3841 gatatagaac ccaatccact agctattata atgattagaa aataaataat ctcaaccact
     3901 ttttaagtcc atcctattct ttcaaacatc taaaacctag atggctacta gtggaagtag
     3961 aaatacatcc atttctagca gctactcggt atcgattaca ataagaacaa tgacataaaa
     4021 aggaacctcc tctgatagca tactcctcat cttgtatccc atattttggt aactcatagt
     4081 catcttcatt aaaactagct aataaggtat atctcggatt gcgacaccat tcccaaacat
     4141 tcccaatcat ttgatataga ccaaaatcat taggtaaaaa ttcatagaca ggagccgttc
     4201 ctataaatcc atctaaggca gtattttcat aaggaaatct tccttgccaa gtattggcat
     4261 gataatatcc accttctaaa agagtatctc cccaaggata ttcagattgt cttcctcctc
     4321 tagcagcata ttcccactgt gcttcagtcg gtaaagacat tccgctccaa ttacagaaag
     4381 ccaatgcatc ttctaaagca acatgaacta ctggatggtc ttctaaaccc actagattac
     4441 tgttctcacc gtagggatgt ttccagcaag cgttcgaaac ttgtaaccac cacggagccc
     4501 cagcaggatg aggatatccc tccctttctg cctccggaac gaacaatata aaaacaaaag
     4561 accactcttg tcgctcagct agtgttttat agcctgtttc tttcacaaat tgagcaaatt
     4621 cttgattcgt aactggagta tccgcaatgg aaaaatcctt tacactaaca gcgacttgag
     4681 gaccttcaaa atcatctaaa aagccctctt cagaatttgt tcccatcata aatgtcccac
     4741 ccttgatttt tttcattttc atgattgact atcccccgtt ttcgttagag ttggcgttat
     4801 tttagaaagt tcaacaggaa ctaactcttc atccacaaca aaaccttctt ctctatatct
     4861 aagaaagtct actaattttt tcttcatctg acgaacaata ggttgatatt tttcacttgg
     4921 atacaaatca ttcatttcat gcggatcttt tttcatatca aataactgat aatgatttaa
     4981 aacaggaaac cagataaatt tccactggtc tgtcaaaata tattgactag aatcttttcc
     5041 taaagtatgt tcaccatgaa attctgttcg ccacccctcg tactgtccaa ataataaatt
     5101 cttaacactc cgtccatcta gttcatctgt agtagttcct cctgccaaat ccacgagtga
     5161 aggaaaaata tcttgaattt tcactaattg cttgattgtt cccctattac cagctatcaa
     5221 tccagccgga tcgtaaataa acgaaggaat gtggatactt ccctgataag gatatccctt
     5281 tctaaacaga taatgttcac caagctgatc tccatgatcc gaaacaaacc agataatcgt
     5341 atctttatca tgacgaaatt cttttagggc agtcaaaaag cgactaattt gatggtctat
     5401 atgagtaatc aatccaaaat aagcagcaac cattcttctt tgatcatctt cctttaattt
     5461 ccctcttaaa gcataaatag acggaatttg cttttctaat acttcccaat tcccgatatg
     5521 caaatcgaga aattgaggca agcgttccat atacatatca aaatagtatt ttgggggatt
     5581 taatggagca tgtggttttt caaaagacat tttgagaaaa aaaggaaccg ttggatctct
     5641 tctttgtaaa aatgaaatgg actcactcac aacccagttt gttggatgta acttctcatc
     5701 tttatcccaa ggtctagctt cccaagaatt acaatccatt ccgtcatcaa tcaaatcaac
     5761 atcataacca actttaccct ttaaaaaggc tagatagtca ctagcataat caaattgact
     5821 tccataagcc ttatcatact ttctatcaac atgtagatac ccatcgtgaa gtaagacatg
     5881 atcaaaccca agtctctgtc tggaaggaaa aacatgcatc ttaccaatac actctgtttg
     5941 ataacccata tctttaaaga cttttggaag agtattagta aaattccaag gcacctcatc
     6001 ttgataacca actcgtccac ttttatcttg gtctaagcca gtcaataaag ctgccctagc
     6061 aggaacgcaa gaaggaactg gagaataggc attttcaaaa ttataaccta cactagccat
     6121 catatctaat gttggagtgc taactagctt atccttacta ttcaaggata aggcgtctgc
     6181 tctcatttga tctacaacaa tcaaaataat atttggctgt tttgtctgaa ccataaaatc
     6241 tcctttctaa tatggcaaaa gaggcacaag aagatatcta cctttactgc acccctttct
     6301 atatcaatct ctctatataa aacaataaca ttcttgttat gttttataga aaaatgaact
     6361 aaaatatgac taaatcgatt aggaaattca aatcattttc tagtactatt ttagaagtta
     6421 cagtgtacta ttccaacttc aataaactat aaacctttgt ctaataacaa ttttagtgga
     6481 gataagaaat cctacaccta actcaatctt acacgtaatc tatttctatt ttatcacaaa
     6541 aaacgcaagt aagaccatta actcaattca gttttatctg ccattttcac aaatgggaaa
     6601 taagtcaaga cactaataat caaacaaaca actgataaga tgatggcacg ccaatcaaat
     6661 gctgtagaga agaaaccata taaaattgga ggcattaccc aagtaacatt ttgtgtaaca
     6721 ggtgaaacaa gaccccagct tgttgcccag taagctaccg ttgccatgaa aaccgggcta
     6781 agtacaaatg gtataaatag caaaggattc aagacaactg gtaaaccata atttaccggc
     6841 tcaccaatat taaacagaac tggtgctaga ccaagtttag caacttttcg ataatgactg
     6901 tttcttgaaa aaattaaaat agcaagtacc aatcctaatc ctccaaacca gacaaacgcc
     6961 ccaaaagacc cacttgtcca tatataagga atcggttcac ctttttggaa agcatccaga
     7021 ttcgctaaca tagcaactcc aaacagccct tccatgatgg gagccaatac atttcctcca
     7081 tggagaccaa aaaaccagaa taacttattt aaaaagatca tcagaataac tgcaaagaaa
     7141 ctttgagaca aacctagtaa tggcgtttgt aacaccttgt aaacccaatc aatcaataag
     7201 taattgctaa gtaaatggaa aacataagtc aagatggcta ctataataca tcgccataaa
     7261 tcctggaatg atagaagtga acggcttagc aatcgcaggg ggaactgaat ctggtaactt
     7321 gattacccag ttctttttca ttactttaca gaaaataata gaggctaaaa atccaatcat
     7381 catggctgta aagtagcctc tggcattaat atggtttcct ggaatcacat tcccaatagt
     7441 taccatcaga tttttaccat caaatgctag attatcaatt ccttgtaaga tttgatctaa
     7501 tttcacatct cctacatttg ccaaagggaa actctttgta actgtacttc caatcgaaat
     7561 gacaaacgaa gcaagcgata ccaaaccagc agaaactgta tcaaccttat aaatcttagc
     7621 gatattcact cccaagcaat agatgaacaa taaggaaaca attggtatac ttcccttgaa
     7681 taccaaatta ttgatgtcaa caagccactg aaaggttttc gtaatacttt ctaggtgaaa
     7741 ttgttgtggt aaatccacta gaaaagcatt taataacaaa gcaatggaac ctgtcataat
     7801 aacaggcata gtccccacaa atgaatcacg taaagcaact aaaaacttct gattcccaac
     7861 tttcattgca attggagaaa gtttttcttg cattttatcc aacattgtat tcatagcaaa
     7921 ttcctaattt ttttcaaatc gttcgtatac ttctaccact tctttcgcca agtcaacaaa
     7981 ggtcagactc gtcattaaat gatcttgcgc gtgtaccatc aagaggctaa ttgatgtttc
     8041 ttccccctgt gcctcttttg tcaacatttc tgtttgagcc ttatgcgcct gtaataaggc
     8101 agcattcgca tcagctaatc ttcgattggc tttagagaaa tcaccttttt ttgctgcctg
     8161 aatagcctcc atagcattac ttttggcttc cccaccatac ataattagcc ccattacaga
     8221 ttctaaatta ctttcattca tagcattctc ctcaatctta gtctaataaa ctttcagcta
     8281 aatctaagac tttagaacca ttcatcattc cgtaatctgt catcggaata accgccacag
     8341 gaatctgtct atcttttagt ttttcttgaa agtcccctag taaatagcga acttgaggac
     8401 ctaaaagcaa cacatttact tcttttgttg ctacaatttc ttctgcttca ggagctggaa
     8461 ctgcaaaaat ttctgcatcc aaccccttat cttctgctgc cttttgcatc tttgtcacta
     8521 gcagacttgt actcatacct gctgcacacg ctaacataat tgttacttta gccatagctt
     8581 actcctttat cacctattta ctgacctagc caagcgagat actgtatgtc tcactcctct
     8641 aattgccttg ctcaatgcat aaatattatc gactgttgcc agtcccccat atcctgcgtc
     8701 acctatatgt tgaatatcaa ctccacaaat tttatttcta agtgcaattt ccttgatagt
     8761 atctgtatca gatgtttctt ggctagtacc aatagcactc agtactagcc cacccttact
     8821 atgaacgaga tcaacgactt cacgcaactc ttggtcatga aaggctggaa cggttccaac
     8881 tgctggaaca agtatcacat ccgcacctgc ttccaacaat tgctctgcga cagaaagctc
     8941 tgccacaggc tcattcactc ctgccccgtg catcttacct gcaataatca aaccagaaaa
     9001 gttttcctta gcagtttgaa cagtcttaat gatttctcga ttgctaactc ctgttccagg
     9061 atttccagtc aaacagacaa agtcaaaacc taactcctct attcgcttca atgtttcaac
     9121 actagcaaca cgacccgcaa caatttcctg tgtttcctct agcatctttg cagatgggtc
     9181 aatcggttcc aaatttacac caattggaca agcaacaagc tggtgtaagc gatgaataac
     9241 atcatcacct gaactatcca aagcataaat tttaggctca aaaacatcaa cacaattcaa
     9301 taaaatcata tcagctccaa aagctctagc aatttcagaa ttagttatat ccccaacaaa
     9361 tgtctcacga gtaactacat tttcagatag aacaactcta ccttcacttg ctaaaatact
     9421 ttgttttaat tcttcagcat tcatctgtaa tatctcagat ggatttgcac taattaaacg
     9481 tttcattctc aatcctccaa taacttaaac cgtttttcaa tagctattac aaatggtaaa
     9541 taaagtaaga catccaaaac aatcaataca atttgtaata atgaaccaga aatacttcct
     9601 gtagcaagta aaccacttat aacaggtggc atagtccaac ttggatctgt ataagttagc
     9661 ggaaccaaac ctgatgccat tgctccccac gctactagta agttaaacat tggagctaag
     9721 ataaatggaa ctagtaacaa aatgttcaaa acaataggaa cgccaaacat tgctggttca
     9781 tttatattaa ataatccagg tataacagtt ataggtgcca aagtttttag ttgtttacta
     9841 gctttcttct tatgtgctaa atatcctaac gcaagaacta aacctatggt tgcaccaccg
     9901 ccacctatga atacaaaatt atccataaat acgctagtaa aaatatttgg aagagtttct
     9961 ccagtttgat aagctacttt atttgcatct agattagcta accataacgg tttcataact
    10021 gcattaacaa catttcctcc gtgtaatcct acaaaccaaa aactactatt aaggaaaatt
    10081 aagataagaa gaccaataac attatttcct aaaagtccaa gtggacctcc caaagctcct
    10141 tgagcaattt catgaagatt aggtaaactt aatttatcta aagttgcata aacaatcaac
    10201 caaccaacaa tagtcactgc accaggaata atggcactaa agcttttaga tactgctggt
    10261 ggaacaccat ccggcatttt tatctgtata ttatgattta taaaccattg gtagatatag
    10321 ccattaatca atcctaaaat catagcaaca aataaacctt ttgatgccat gaaagcggta
    10381 ggcattcctg ctccagcctc tcctgtaatg aaaggcgtaa ctgtaataaa agatgataat
    10441 gacacaatac cagcaggaat accatcaact ttgtattgtc tagccataaa gtaagcgata
    10501 ccaaaactag ctacaagacc aagtaatcca aaactactat caacaccctt ccataaatag
    10561 tcagcaacac caatatcacc tagatatttt tcccatcctg gaataggaaa acttgcaata
    10621 accattagta atgaacctat caacaataaa ggtatagtta gagtaatacc gtctcgaata
    10681 gaaaccaacg ctttattatt acccaatcta gccgctactg gaagtaactt ttcttgtaat
    10741 aatttttcca taaccttttc ctcttaaata tattttatta tcaaaagtta tcaattatct
    10801 ttattttttg acgtcaagtt atta
//
LOCUS       DBJKQU010000056        10787 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.056, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000056 DBJKQU010000000
VERSION     DBJKQU010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10787
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.056"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..190
                     /locus_tag="ACSUUC_001788"
     CDS             <1..190
                     /locus_tag="ACSUUC_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054950.1"
                     /translation="KKMFLKLMETDKIENDIFYLDGIKSILPLLSLDDRRNVLQHIQK
                     QNNCPPPEIEELQRIIVN"
     gene            291..1169
                     /gene="truB"
                     /locus_tag="ACSUUC_001789"
     CDS             291..1169
                     /gene="truB"
                     /locus_tag="ACSUUC_001789"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HHQ8054951.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            1410..1712
                     /locus_tag="ACSUUC_001790"
     CDS             1410..1712
                     /locus_tag="ACSUUC_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HHQ8054952.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            1820..2458
                     /gene="udk"
                     /locus_tag="ACSUUC_001791"
     CDS             1820..2458
                     /gene="udk"
                     /locus_tag="ACSUUC_001791"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HHQ8054953.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            2586..3926
                     /gene="xseA"
                     /locus_tag="ACSUUC_001792"
     CDS             2586..3926
                     /gene="xseA"
                     /locus_tag="ACSUUC_001792"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HHQ8054954.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            3904..4116
                     /locus_tag="ACSUUC_001793"
     CDS             3904..4116
                     /locus_tag="ACSUUC_001793"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HHQ8054955.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIDLEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            4113..4988
                     /locus_tag="ACSUUC_001794"
     CDS             4113..4988
                     /locus_tag="ACSUUC_001794"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HHQ8054956.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            4981..5796
                     /locus_tag="ACSUUC_001795"
     CDS             4981..5796
                     /locus_tag="ACSUUC_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HHQ8054957.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     NLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            5789..6220
                     /locus_tag="ACSUUC_001796"
     CDS             5789..6220
                     /locus_tag="ACSUUC_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HHQ8054958.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            6227..7894
                     /gene="recN"
                     /locus_tag="ACSUUC_001797"
     CDS             6227..7894
                     /gene="recN"
                     /locus_tag="ACSUUC_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HHQ8054959.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMTEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            7896..8624
                     /locus_tag="ACSUUC_001798"
     CDS             7896..8624
                     /locus_tag="ACSUUC_001798"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HHQ8054960.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            8703..10526
                     /gene="lepA"
                     /locus_tag="ACSUUC_001799"
     CDS             8703..10526
                     /gene="lepA"
                     /locus_tag="ACSUUC_001799"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HHQ8054961.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDVLSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(10607..>10787)
                     /locus_tag="ACSUUC_001800"
     CDS             complement(10607..>10787)
                     /locus_tag="ACSUUC_001800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054962.1"
                     /translation="TRKLAAGCSKHSFEVVDETDEVSSKHGFEVVDETDEVSNHTYGK
                     ATLTWFEEIFEEYKN"
BASE COUNT         3193 a         1950 c         2618 g         3026 t
ORIGIN      
        1 gaaaaaaatg tttctgaaat taatggagac cgataaaata gagaatgata ttttttattt
       61 agatggcatc aaaagtatac tcccattatt atctttagat gacagacgaa atgtattaca
      121 acatattcaa aaacagaaca attgtcctcc tccagagatt gaggaattac aaagaattat
      181 agttaattaa attttgtaaa aaagagaata aaaggtagac gacgcctcag taaaaattgg
      241 cccggaaaaa agcgaagttc gaagcactga agggggagta gaaagcaaaa atgaacggta
      301 ttatcaactt aaaaaaagaa gcaggaatga cctcgcatga tgcggttttt aaactgcgta
      361 agattttggg aaccaagaaa attggtcatg gtggaacctt ggatccggat gtggtgggtg
      421 ttttgccgat tgcggttggc aaggcgacac gcatggtcga gtttatgcag gacgagggta
      481 agatctatga gggggaaatt actctgggtt attccacgac gactgaggat gctagtgggg
      541 aagtgatcgc agaaacccct gttttgtctc ccttggatga aaagcttgtt gatgaagcga
      601 ttgctagctt gactgggcct attacccaga ttccccctat gtattcggca gttaaggtta
      661 atggtcgcaa gctctatgag tatgcgcgtg ctggtcagga agtggagcgt ccagaacgtc
      721 aggtgaccat ttatcaattt gagcgaacaa gtccgatttc ttatgatggc caacttgctc
      781 gattcacttt tcgtgtaaaa tgcagtaaag ggacttacat ccgtactttg tcagttgatt
      841 tgggtgaaaa gcttggttat gcggctcata tgtcccattt gactcgtact agtgctgctg
      901 gcttacaatt agaagacgct cttgccttgg aggaaattgc tgaaaaagta gaggctgggc
      961 aattagattt tctccatcct ttagagattg ggacaggtga ccttgtcaaa gttttcctaa
     1021 ctccagaaga ggctacagaa gttcgctttg gtcgttttat tgagctagac caaacggaca
     1081 aagaactggc tgcctttgaa gatgataaat tgttagccat tctagaaaaa cggggcaatc
     1141 tctataagcc aaggaaggtt tttagctaga tcgtttagga ataaaaatcg ggtgatagat
     1201 aacaattgct tgataaaacc ccatactaat agtagaatgg ttttgggaat tataatattc
     1261 caattgttgc gagttgtagg tactcaaata atctatatag aaatttagag gtgtgaaatg
     1321 aagcaattta aaattctttc agataaatat ttagagtcca ttacaggttc tggtgggaac
     1381 ttaggcccag gatttggtgt gataattcca tgatgcgaaa tgagtttcga gaaagggtgg
     1441 agcaacttct tcaacaaaaa gaaataaatg aaaatagtga gttgagtcac ctgtttcgtc
     1501 ttgctataca aaatttagac agaaatgaaa aataccaatc ggtcatggcc aatttgagtc
     1561 aagggttgtc actttacctc atgacgcatc attaccaggc acctaagtct gtcattgatt
     1621 ttggtttatg gattgccaaa gctcctagcc aggaaagagg gagactggct ttcttgcaga
     1681 tgcttgctca aaccctacag ggctttcgtt aaaactgtcg aacatcagag ggaagactct
     1741 ggtgtttttt gctgatgaga ctataaattt tgtaaaaaat gtgatagaat agacgacgga
     1801 taaaataacg gaggatagca tgcaaaatag accaatcatt attggagtga caggtggttc
     1861 tggtggtggt aaaaccagtg tttcaagagc cattttatcg cattttcctg atgaaaagat
     1921 ttccatgatt gagcatgatt catactacaa ggatcagtct catttgacct ttgaagagcg
     1981 tgtcaaaacc aactatgacc atccttttgc ctttgataca gacttgatga tcgagcagat
     2041 taaggaattg ttggcagggc gtccggtgga catcccgacc tacgactata cagagcatac
     2101 acggagtagc aagacctatc gtcaggagcc tcaagatgtc tttatcgttg agggcatttt
     2161 ggtcttggag gacaagcgtc tgcgcgattt gatggatatc aagatttttg tggatacgga
     2221 tgacgatgta cgtattattc gtcgtatcaa gcgtgatatg gaggagcgtg gccgtagcct
     2281 tgatagcgtt attaaccagt acttaggtgt ggtcaaacca atgtaccacc agtttatcga
     2341 gtcaactaag cgttatgctg atatcgtcat tcctgaaggg gttagcaata ccgtggctat
     2401 cgacctgttg acgaccaaga ttgcaaagat tttggaagaa gctcgaaaca gcaaataatc
     2461 acatgtggag gccttgcctc ctttttctat ttttccctca taatggtaca taaatggaga
     2521 tttttaggca tatttttggt ataataatac ccatgaaaga gcaagtaaat gaatagtagg
     2581 tggagatgga aaagtattta tcggtaacaa ctttgaccaa gtatctgaaa atgaaattcg
     2641 ataaagaccc atacttggaa cgggtctatt taactggtca agtttccaac tttcgtaaac
     2701 gacctactca ccaatatttc tccctaaagg atgaccatgc agttattcaa gcgaccatct
     2761 ggtctgggat ttatcagaaa ttagggtttg acctggaaga aggaatgaag atcaatgtga
     2821 ttgggcgtgt acaggtctat gaaccaagtg gtagctactc catcatcatt gaaaaagctg
     2881 agcctgatgg ggttggggcg cttgcgattc agtttgaaca acttaagaaa aaattgacag
     2941 aagaaggcct gtttcaagaa cgcttcaagc aagctctgcc ccaattttct aagagaattg
     3001 gtgtagtaac cagccgtagt ggagccgtta ttcgagatat tatcacgacc gtcagcaggc
     3061 gattcccagg tgttgacatc cttctttatc cgaccaaggt tcaaggtgaa ggggctgcgg
     3121 aggaaattgc tagaaatatt gcgcgtgcta atcaacggga cgatttggat ttgctcatta
     3181 ttggtcgtgg aggtggttct attgaggatc tctgggcctt taacgaagaa attgtggtac
     3241 gagctatttt tgaatctcgt ttgccagtta tctctagtgt ggggcatgag acggatgtga
     3301 ccttggcaga ttttgtggca gatcgacgcg ctgcaacgcc aacagcggcg gctgaactgg
     3361 caacacctgt gaccaagttg gatgtattag ctcatttgca aaatcaggaa aaacggatgg
     3421 taacggcagt ccgaaatgtt ctatctaaga aacaagaggc tttgaaaaaa tgcagtcagt
     3481 ctgttatctt tagacaacct gagcgcttgt atgacggtta tttgcaacgc ttggaccaac
     3541 tgcaactgcg tttgaaacaa agtttgcgaa ctcggatttc tgataacaaa caattagttc
     3601 aagcaagaac tcatcaatta gtacaattat cacctgttac caaaatccaa cgctatcaag
     3661 accgtttagg acagttggac aagctcttag gtagccaaat ggcgttagtt tatgacgcca
     3721 aggttgctga ggccaagcga ctttcggaag ctttgctcat gttggatact agccgaatcg
     3781 tggcgcgtgg ttatgctatt gtcaaaaaag aagagtccgt tgtagattcg gttgagagtt
     3841 tgaagaaaaa agaccaagta acgcttttga tgcgagatgg tcaagtagaa ttagaggtta
     3901 aagatgtcaa aacaaaagaa atttgaggaa aatctagcag aactggaaac cattgtccaa
     3961 agtttggaaa atggtgaaat tgatctggaa gatgcgatta ctgcctttca aaagggcatg
     4021 gtcttgtcaa aagagctcca agctacgctg gacaaggctg aaaagacctt ggtcaaggtc
     4081 atgcaagaag acggaacaga aagtgatttt gaatgaaaaa gcaagaaaaa ttagctcttg
     4141 tcgagtcggc tttggaagat ttttatggag accagcagtt tgcctctagt ttacgggagt
     4201 ctgttctcta ttctattcat gctggtggca agcgtattcg gccttttctc ttgttagaag
     4261 ttctggaagc cttgcaggtt accatcaaac ctgctcacgc gcaggtagct actgccttgg
     4321 agatgattca tacagggagc ttgattcacg atgaccttcc tgctatggat gatgacgatt
     4381 atcgaagagg gcggttaacc aatcacaaga aattcggtga agctatggcc attttggctg
     4441 gagatgcctt attcttagac tcatatgcct tgattgcgca ggcagatttg ccaagtcaga
     4501 ttaaggtgga cttgattgcc aacttatccc ttgcttcagg tagtctgggt atggtggcag
     4561 ggcaagtttt ggatatggag ggcgaacacc agcacttgtc tctggaagaa cttcagacta
     4621 ttcatgccaa taagactggg aagttactag cctatccctt ccaagcggca gctattatag
     4681 ctgaattgtc acctgaaatg caggtgaagc tgaaaactgt gggtgaattg attggacttg
     4741 cttttcaagt cagagatgat gtactggatg tgacagctag ttttgaggaa atcggcaaga
     4801 cacctcaaaa ggatctgcag gcagaaaaat caacctatcc tgccctgttg ggcttggaag
     4861 agtccattgc cttttgtaac caaaccctgg atcaagctaa tgaaaaatta gaagaaattg
     4921 cccagcagct tccctttgaa acagaatcga ttgtaagtgt agtagaaagt ttgagaatca
     4981 atggctaagg aaagagtgga tgtactagct tataaacagg ggttgtttga aacgagagag
     5041 caggccaagc gaggtgtgat ggctggccta gtcgtagcag tccttaatgg agaacggttt
     5101 gacaagccag gagagaaaat tccagatgac accgaattaa aactcaaggg ggagaaactc
     5161 aagtatgtca gccgtggtgg tttgaaactg gaaaaggcct tgcaggtctt tgatttgtcg
     5221 gtggatggcg cgactacgat tgatatcggg gcctctactg gaggttttac cgatgtcatg
     5281 ctacagaata gtgccaagtt ggtctttgca gtcgatgttg gtaccaatca gttggcttgg
     5341 aaattacgcc aagacccacg agttgtcagc atggagcagt tcaatttccg ctatgctgaa
     5401 aagactgatt tcgagcagga gccgagcttt gccagtattg atgtgagttt catttccctt
     5461 aatctgattt tgccagcctt gcaccgtgtc ttggctgatc aaggtcaggt ggtagcactt
     5521 gtcaaacctc agtttgaggc aggacgtgag cagattggga aaaatggaat tattcgagat
     5581 gctaaggttc atcagaatgt ccttgaatct gtaacagcta tggcagtaga ggtaggtttt
     5641 tcagtccttg gcttggactt ttctcccatc caaggtggac atggaaatat tgaattttta
     5701 gcgtatttga aaaaagaaaa gtcagcaagc aatcagattc ttgctgagat taaagaagca
     5761 gtagagaggg cgcatagtca attcaaaaat gaataaaaaa gaaagacttg aaaaaattag
     5821 aagattggtg acagattatc aaatcggcac gcaagaagaa attgtagaac atttgaaaga
     5881 agcaggtatc actgccactc aggcgacggt atcccgagat atcaaagagt taggtattgt
     5941 caaaattcct ttgagagaca acacttatgt ctacgaatta ccaaaatcaa tcgtaaaaag
     6001 tctgcaactg gctgaagaca atatcgaatc ggctgaattg atggataaga tgatcaatct
     6061 ccaagttatt ccaggaaata cggcttttgt aaaagctcag ttaatcgaga cttttgcaga
     6121 caagattttt agctgtttga ctgatgatag ctcgatttta gtcattgcca gaagtggaag
     6181 tctagcagag gaaatctttg aacaagtaaa aaattggtag gtctatatgt tacttgaaat
     6241 ttcgataaaa aactttgcca ttattgaggc tatttccctc aattttgaaa aggggatgac
     6301 tgtcctgact ggtgaaacgg gtgcagggaa gtcgattatc attgatgcca tgaatatgat
     6361 gttgggagct cgtgcgacga cagatgttat tcgtcatggt gcaccaaagg cagagattga
     6421 ggggcttttc tcagttgaga atagtcgtct tttacaggaa atttttgatg agcaaggttt
     6481 agaattaggt gatgaaatta tcatccgtcg ggaaatcttg caaaatggtc gtagtatcag
     6541 ccgtgtaaat ggtcagatgg ttaatctgtc tgttttgcga gctattgggc aacatcttgt
     6601 agatattcat ggtcagcatg accatgagga gttaatgcgt ccccaactgc atatccagat
     6661 gttggatgaa tttggtgatg ccgctttttg ggacttgaaa gaaacctatc aaacgagttt
     6721 tgatgcctat cggaaaatgc gtaagcaggt tctggaagtc aagaaaaacc aacaggaaca
     6781 caaggcacgt atcgaaatgt tggaatttca aatgacagag attgaggcag caaacttgca
     6841 ggctggagaa gacttggctc tcaatcaaga acgagataaa ctcctcaacc acaaaaatat
     6901 tgcggataca ctgaccaatg cctacagtat gttggacaat gaagattttt caagtctggc
     6961 caatgttcgt tcagctatga atgacatgga aagtgtcgaa gagtatgatc ctgaataccg
     7021 tgaaatttca agctctctgt ctgagaccta ctatgtttta gaagacatta gcaaacgttt
     7081 ggaagctatc attgaggacc ttgattttga tggcaatcgc ctcatgcagg ttgagaatcg
     7141 tttggacctc cttcatacta ttactcgtaa gtatggtggg actgttgatg atgttttgct
     7201 ttattttgcc aagattacgg aagaatacaa tctcttgaca ggcaataatc tttcgtctga
     7261 ggacatggaa gcagagctta agaagttgga agtcaatctt gtcaatttgg caggtcaact
     7321 tgcttctgct cgtcataatt tggctcagca actcgaagct gagattaaac aagaactgca
     7381 agatctttat atggaaaaag cccagtttca ggttcgtttt agtaagggaa aattcagtcg
     7441 tgagggaaat gaaatggttg agttttatat ttcaaccaac cctggagaag actttaaacc
     7501 cttggttaag gttgcttctg gaggggaatt atctcgtctc atgttagcca ttaagtctgc
     7561 cttttcacgt aaagaaggca agactagcat tgtctttgat gaggtggata cgggagtttc
     7621 aggtcgtgtt gctcaagcta ttgctcagaa aattcataaa attggtcagt atggtcaggt
     7681 tttggctatc tcccatttgc cacaagtaat tgcgattgca gattatcaat tctttattga
     7741 gaagattagt aatgaccatt caacggtttc gactgttcgt ctcttgacag tcgaagagcg
     7801 agtggaggaa gttgccaaga tgttggcagg tgatgatgtg acagaagcag ccctgacgca
     7861 agccagagaa ttgttgagaa acagggagaa ataagatgac agattattat gtaattggag
     7921 atgttcacgg aaaagctggg atgctggaag accttcttaa aacctgggat ggtcagaccc
     7981 agttgctctt tctaggtgat ttgattgaca gaggtgagga tagtcaccgt gttcttgaaa
     8041 tggtcaagga cttggtggac aatcaagggg ctatctgttt gtctggaaac cacgagtata
     8101 tgtttttgac ttggctagat gacccagaag aaagttatga ccattatcgt cgcaatggtg
     8161 gagatacaac cattaactct atcctaggtc gtcccttgga tgcaccagtt gatggagtag
     8221 aagatgccaa gcgggttgcc gctgaagcgg cagacttggt cgaattcatt cgtcaaatgc
     8281 catttgtagt agagacagac aagtatatct ttgttcacgc aggtattgat ttgaccttgg
     8341 acgactggca tgaaacaaca gattataaaa aagtatggct tagaaaacca ttccacggag
     8401 ctgaaaatca tactggaaaa accattgtct tcggtcatac accggtctat ggtttgttac
     8461 agcaagaacg cggtacatct gagctttgga ctacagaaga tggcaagatt ggaatggatg
     8521 gaggagctgt ttatggtggt gtccttcacg ggattgtctt tacagaccaa ggaatgacag
     8581 aacaccactt tatcgaaaat gacggctttg tcgctgaaga ttagtactct tagcagggta
     8641 tggtcttgtc aaaatatcaa aaacaattta taataaatag ataccctgaa aggaagagaa
     8701 tcatgaactt agaagaattg aaaaaacgac aggagaagat ccgtaacttc tctattatcg
     8761 cccatattga ccacggaaaa tcaactctag cagaccgcat tttggaaaaa acagagacgg
     8821 tttcaagtcg tgaaatgcag gcccagcttt tggatagcat ggagctagag cgggaacgtg
     8881 gaattactat taagttgaat gccatcgagt tgaattacac tgcaaaagat ggggaaactt
     8941 atattttcca cttgattgac acaccagggc acgttgactt tacctatgaa gtttcacgtt
     9001 cgctagctgc ctgtgagggt gctattttgg tggtcgatgc ggctcaagga attgaggctc
     9061 aaactcttgc caacgtttat ctggctttgg ataatgattt ggaaatcatg cctatcatta
     9121 ataaaattga cctgccggct gcagatccgg agcgcgtgcg tacagagatt gaagatgtga
     9181 ttggtttgga tgccagtgaa gcagttttgg cttctgccaa ggctggtatt gggattgaag
     9241 aaatcctcga gcaaattgta gaaaaagtac cagcaccaac gggtgatgtg acggcgccac
     9301 ttaaggcctt gattttcgac tctgtttacg atgcttaccg tggggttatc ctccaagtac
     9361 gtgtcatgga cggagtggtc aaacctggtg ataagattca gctcatgagc aatagtaaga
     9421 cctttgatgt gaccgaagtc ggtattttta caccaaaagc ggttggtcgt gatttccttg
     9481 cgactggtga tgttggttac attgcggcgt ctatcaagac ggttcaggat actcgtgtgg
     9541 gtgataccgt taccttggca accaatcctg cggcagaacc attacatggt tataagcaga
     9601 tgaatcctat ggtctttgcg ggtctctacc caatcgaatc aaacaagtac aatgacctgc
     9661 gtgaagcgct tgaaaaattg caactgaatg atgctagtct tcagtttgaa ccagaaacat
     9721 ctcaggcact tggatttggt tttcgttgtg gatttcttgg acttctccat atggatgtga
     9781 tccaggaacg tttagagcgt gagttcaata ttgacctcat catgacagct ccgtctgtta
     9841 tttacaaagt taatttgacc gacggtgagt ctatggatgt gtctaaccca tctgagtttc
     9901 cagacccaac taagattgcg accattgaag agccttatgt caaggcgcaa atcatggtac
     9961 cacaggagtt cgtcggagca gtaatggagc tagctcagcg taagcgtggg gactttgtga
    10021 ctatggacta tattgatgat aaccgtgtca atgttatcta tcaaattcct cttgctgaaa
    10081 ttgtctttga cttctttgat aaacttaagt cttcgacacg tggttatgca agctttgact
    10141 acgaattgtc agaatatcgc ccatctaagc tggtgaaaat ggatatcctt ctcaatggag
    10201 ataaggtgga tgtcctcagc tttatcgttc acaaggactt tgcctacgaa cgtgggaaac
    10261 tcatcgttga taaactcaag aaaatcatcc ctcgccaaca atttgaagtt ccaatccaag
    10321 cggctattgg acacaagatt gtcgctcgta ctgatatcaa ggcccttcgt aagaacgtac
    10381 ttgctaaatg ttatggtggt gacgtttctc gtaagcgtaa actccttgaa aaacaaaaag
    10441 ctggtaagaa acgcatgaaa tccatcggat cagttgaagt tccgcaagaa gccttcctca
    10501 gcgtcttgag tatggatgaa gaataagtta tcagaaatgc ctttccttgt tcacaggaaa
    10561 tttatataag aatcaatagt aaagcaggct tagatggtct gcttttttag tttttatact
    10621 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtatgg ttactgactt
    10681 cgtcagtttc atctacaacc tcaaaaccat gttttgagct gacttcgtca gtttcatcta
    10741 caacctcaaa actgtgtttt gaacaacctg cggctagctt cctagtt
//
LOCUS       DBJKQU010000057        10592 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.057, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000057 DBJKQU010000000
VERSION     DBJKQU010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.057"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            118..897
                     /locus_tag="ACSUUC_001801"
     CDS             118..897
                     /locus_tag="ACSUUC_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054963.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYTF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            899..1081
                     /locus_tag="ACSUUC_001802"
                     /pseudo
     CDS             899..1081
                     /locus_tag="ACSUUC_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1543..1776
                     /locus_tag="ACSUUC_001803"
     CDS             1543..1776
                     /locus_tag="ACSUUC_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HHQ8054964.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPIMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            1776..3110
                     /locus_tag="ACSUUC_001804"
     CDS             1776..3110
                     /locus_tag="ACSUUC_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HHQ8054965.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQERFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIADESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            3120..3374
                     /locus_tag="ACSUUC_001805"
     CDS             3120..3374
                     /locus_tag="ACSUUC_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HHQ8054966.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            3470..3865
                     /locus_tag="ACSUUC_001806"
     CDS             3470..3865
                     /locus_tag="ACSUUC_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HHQ8054967.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            4391..4726
                     /locus_tag="ACSUUC_001807"
     CDS             4391..4726
                     /locus_tag="ACSUUC_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054968.1"
                     /translation="MSHQEKLERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDG
                     ICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIK
                     KARKKDGKN"
     gene            4713..5273
                     /locus_tag="ACSUUC_001808"
     CDS             4713..5273
                     /locus_tag="ACSUUC_001808"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8054969.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            5273..5851
                     /locus_tag="ACSUUC_001809"
     CDS             5273..5851
                     /locus_tag="ACSUUC_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHQ8054970.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            5844..8495
                     /locus_tag="ACSUUC_001810"
     CDS             5844..8495
                     /locus_tag="ACSUUC_001810"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HHQ8054971.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAINPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            8565..9320
                     /locus_tag="ACSUUC_001811"
     CDS             8565..9320
                     /locus_tag="ACSUUC_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HHQ8054972.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            9599..10402
                     /locus_tag="ACSUUC_001812"
     CDS             9599..10402
                     /locus_tag="ACSUUC_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HHQ8054973.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQARGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADMVKKIQHFISGIWQIHPFREGNARTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(10518..>10592)
                     /locus_tag="ACSUUC_001813"
     CDS             complement(10518..>10592)
                     /locus_tag="ACSUUC_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HHQ8054974.1"
                     /translation="YNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         3186 a         1971 c         2366 g         3069 t
ORIGIN      
        1 tttcatttca ctataaaaaa ggggttctgt attttttaat gttatctaat tagaaaatgc
       61 tttttttgta ggaaatataa tatgataagg tgcaaaaaag aaataaggag tttgtatatg
      121 gctgaacaag acttagctat gcaagtattg caacaagtgg tgaaactacc tgttgttaag
      181 gttgatcgtt cgaaattttt agtggataag ttttccaaag aattgggtcc acaggacatt
      241 cctaccttat tggaacaagg tccaacgtct ctcttatctc aagaaatctt agatcgagtg
      301 gctaatgcct gtattaggga taatgtttta ttagcgagtg ggacttctgt tttggcagga
      361 ttacctggag ggcttgctat ggcaattacc attccagctg atgtggctca attttatact
      421 ttctctctaa aattggctca agaattaggt tatatttatg gttatgagga tctttgggct
      481 tcacgcgagg agttgagtga agatgctcaa aataccctct tgctttatct aggcgtcatg
      541 ttgggggtga atggaaccgc tgctttgcta cgtgctggtg gtataacaat tgccaaacag
      601 gtaatgaaaa cagtgcctaa taaagcttta acaaagacgc tttggtaccc tattttgaaa
      661 aaagtcttaa aaatatttgg tgtgaatctt accaagggag ggctggccaa aggaataggg
      721 aaatttattc ctatcttggg tggtatcatt tcaggtggtt taacctttgc aactatgaaa
      781 ccgatgggtg aaagcttgca gaaagaattg tccaagctag ttaactatag tgaagttcaa
      841 tatcaagaag atgttgaaac aatccgaaaa gaggctgaaa tcatcgaagg agagtaatat
      901 gggactcata aaaactctag ctaaaattta tggtaattac tttttgaccg tgtaaggtgt
      961 aaaagtaatg aaaacgataa agaaagatga taatgccgtt gtcggtctgg ggaaactttt
     1021 tattgccgac aagttaatgg atacggctcg gtggctcatt aagccagagg ataaaaaatg
     1081 aaatttttct ggggacttct tgccattatt tttatcaaac cgattattgg gattgtgaaa
     1141 ttcttttgga tgatcatctc ttttgcagtc caattgctgt tttacaagat agtgtttaag
     1201 atattggatt ggctctttaa acttatctag atggtaatcc aagtcgcaga gaactagcag
     1261 gaactccact gctagttttt tattctcttt ccatatggta taatataagc agtaaaatca
     1321 ttttatactc ttcgaaaatc tcttcaaacc acgtcagctt caccttgctg tatatatgtt
     1381 actgacttcg tcagttctat ccacaacctc aaaacggtgt tttgagctga cttcgtcagt
     1441 tctatctaca acctcaaagc actgttttga gcaacctgcg gctagcttcc tagtttgctc
     1501 tttgattttc attgagtatt agaacataca atggaggtcg tcatggacaa tatcatcgat
     1561 gtgtcaattc ctgttgcaga agtggtggac aagcatccag aagtcttgga aattctagtg
     1621 gagttgggtt ttaaacccct tgccaatccc ataatgcgca atacagttgg tcgtaaagta
     1681 tcacttaaac agggttctaa gctagcagga actcctatgg acaagattgt acgcacactg
     1741 gaagcgaatg gctacgaagt gattggatta gactaatgac agatgaacgg attcatatcc
     1801 tacgggatat tttgttagaa ttgcacaatg gcgcctctcc tgagtcggtt caagagcgct
     1861 ttgatgcgac ctttacgggc gtgtcagcca tcgagatttc ccttatggag cacgagctga
     1921 tgaactcgga ttcgggcgtc acttttgaag atgttatgga actctgtgat gtccatgcca
     1981 atctttttaa aaatgctatc aaaggtgtcg aagttttaga taccgaacac cctgggcacc
     2041 cagttcgtgt ctttaaggaa gaaaatttgg ccctccgtgc agctttgatt cgcattcgta
     2101 gattgttaga tacctatgag tctatggaag acgaggaaat gcttgcggag atgcgcaagg
     2161 gcttggtgcg tcagatggga cttgtggggc aatttgacat ccattaccaa cgtaaggaag
     2221 aactcttctt tcctatcatg gagcgctatg gacacgattc acctcccaaa gttatgtggg
     2281 gagtggatga tcagattagg gaactctttc aaacagctct aacgacagcc aagtcactac
     2341 cagaagtgtc aattagcagt gtaaaggaag cttttgaagc ttttgcgaca gagtttgaaa
     2401 gtatgatttt caaggaagag tccatcctcc tcatgattct ccttgagtct tttactcagg
     2461 atgactggct tcagattgcg gatgagagcg atgcctatgg ctatgccatc atccgtccgt
     2521 cagagaaatg ggtgccagaa cgacagagct ttattgagga aaagattgca gaggagcctg
     2581 tacagctaga tacggcagaa ggtcaagttc aacaagtcat agatacgcca gaaggccatt
     2641 ttaccattac ctttacccct aaggaaaagg aagctgtgct ggaccgccat agtcaacagg
     2701 cttttggtaa tggctatctt tcagtcgagc aggccaatct catcctcaat catctcccta
     2761 tggagattac ctttgtcaat aaagaagata ttttccagta ttacaatgac aatacgccag
     2821 ctgatgagat gattttcaaa cggacgccgt cccaagtcgg gcgcaatgtc gaactctgtc
     2881 atccgcctaa gtatttggac aaggtcaaaa ctatcatgaa ggggcttcgt gaggggacca
     2941 aggacaagta tgaaatgtgg ttcaagtctg agtcgcgagg taagtttgtc cacatcacct
     3001 atgctgcagt acacgatgaa gacggagaat tccaaggagt gttggagtat gttcaggata
     3061 tccagcccta ccgtgagatt gatacggact attttcgtgg attagaataa ggagaaaaaa
     3121 tgagttacga acaagaattt atgaaggaat ttgaagcttg ggtcaatacc caaatcatga
     3181 ttaacgacat ggcgcacaag gaaagtcaaa aagtttacga agaagaccag gacgagcgtg
     3241 ccaaagatgc catgattcgc tacgagagtc gcttggatgc ttatcagttc ttgcttggta
     3301 agtttgaaaa cttcaaagca ggcaagggat tccatgattt gccagaaggc ttgtttggtg
     3361 agcgaaatta ttaaacgaga aagattcttg atttttcact aaaatcttga tagaatgttt
     3421 atgttaaatc cttgtcagag cagggatttt ttattgaaag gattttatca tgtcaaagaa
     3481 actcaatcgt aaaaaacaat tacgaaatgg cctccgtcgc gcaggtgcct tttcaagtac
     3541 tgtgactaag gttgtagatg agacaaaaaa agtcgtgaag cgtgcagaac agtcagcaag
     3601 cgcagctggt aaggctgttt ctaaaaaagt tgaacaagca gtagaagcta ccaaagagca
     3661 agctcaaaaa gtagctaatt ctgtagaaga ttttgcagca aacttgggtg gacttccact
     3721 tgatcgtgcc aaaactttct atgatgaagg aatcaagtct gcttcagatt tcaaaaactg
     3781 gactgaaaaa gaactccttg ccttgaaagg aatcggccca gctaccatca agaaattgaa
     3841 agaaaatggc atcaagttca agtaattttt cttgagcctt gcatttccga gaaaaacttg
     3901 ctacaataga gccattagag gtgttttgaa tcccacattt tacagaaagt ggcggcgctg
     3961 agaagtccac aaatgtgtca aaactggttg ctaatgactg aaaaaatgaa atatttctgt
     4021 ctttttattt taaagactaa agatgcgggc ttggcccgaa attgggtggt accgcggata
     4081 aacacattcg tccctgtcat gtagatggca gggcttttct tttgtgtctt agtcaaagga
     4141 ggttgttata aaacaatcat ttaaaactaa taaactatat tatggttttc ctgtttttat
     4201 tttaggatat caagattaga attttggcta taacatcacg acctgtagtt cctcttatag
     4261 tctaggagat tgggttgtga ttggagtcgt tgcgagagag aatgccgcag agcagatcaa
     4321 acagtatcaa aaatttactg tgaatatttc tgatgaaact tctatgcttg cgatggagta
     4381 ggctggtttt atcagtcatc aggagaaatt ggaacgtttg ggagtgcatt atgaaatttc
     4441 tgaacgaact cagattccta ttttagacgc ctgtccactt gttttagatt gtcgggtaga
     4501 taggattgtt gaggaagacg gtatttgcca catctttgcc aagattcttg agcgacttgt
     4561 tgccccagaa ctcctggatg aaaagggaca ttttaaaaat caactgtttg ccccaaccta
     4621 tttcatggga gatggatatc agcgcgttta tcgctatctg gacaagcgtg tagatatgaa
     4681 gggcagtttc atcaaaaaag cgaggaagaa ggatggcaag aactgagctg ccagataaaa
     4741 tcgaaacaga acgtctcgtt ttacgagtcc gtactgtggc ggatgctgag gatatctttg
     4801 actatgctag tttgccagag gtcgcctatc cagcaggttt tcctccagtc aagaccttgg
     4861 aagatgagat ttattatctg gagcacattc ttccggagcg taatcaaaag gaaaatctcc
     4921 cagcaggcta cgggattgtc gtcaaaggaa cggataagat cgttggctct atctatttca
     4981 accatcgcca tgaagatgat gtgatggaaa tcggctatac cttacactca gactattggg
     5041 ggcgaggtta tgtgccagaa gctgcgcgtg ccttgattga cttagccttt aaagatttgg
     5101 gtcttcacaa gattgaacta acttgctttg gatataacct tcaaagtcaa cgagtcgcgg
     5161 aaaagcttgg ctttaccctc gaagctcgca taagagaccg taaagatgct caaggcaact
     5221 gctgtgatga tttgagatat gccttgctga agagtgagtg ggaggtgatt tgatgcatct
     5281 tttcatcatt ggtgctccag catcaggaaa aatgaccatt ggtcaagaat tatctcgact
     5341 gacggatgct accctatttt ataaccatca agccattgat tttgcactag aaatctatca
     5401 ggactataca gaggaaatgt gggaatttgt tcgtggaatc actttttcat tccttggagc
     5461 aagtgcaaga aatcagcgat cagtaatttt aacagatgta attgattttt caaatcagta
     5521 tcagctgatg tatttaaagc aaattcagaa tttgttggat gattatcatc aagagattct
     5581 ttttgttgag ttggaaacaa gtcttgaaga gtgcatacgt cgaaatcgaa cggagaatcg
     5641 attaaagcac aaacccttaa aacgacatat tgaggtatct gaaagagaaa ttttagagac
     5701 cgctgaaaca cttcaattaa attcccaata tcaaccgaat gagttgcacc actactttaa
     5761 aataaataat acgaatttgt ctgcagaaga agctgctaag caaattcaaa ataaaataaa
     5821 caaaatagag aaaggacaca cacatgtcta aagaactttc atctaaatac aatccagccg
     5881 aggttgaggc tggtcgttac caaaaatggc ttgatgcgga tgttttcaag ccttcaggcg
     5941 atcaaaaggc taagccttat tcaatcgtga ttccaccacc aaacgtaact gggaaacttc
     6001 accttggtca cgcttgggat acgactttgc aggatatcat catccgtcaa aaacgcatgc
     6061 agggctttga taccctttgg cttccaggta tggaccacgc tggtattgcg actcaggcta
     6121 aggttgagga gcgcttacgt ggtgagggta ttacgcgtta tgacctaggt cgtgagtctt
     6181 tcttgacgaa ggtctgggaa tggaaagacg aatatgccac taccatcaag gaacaatggg
     6241 gcaagatggg gctttctgta gactattctc gtgagcgttt cactcttgac gaaggtttgt
     6301 caaaagctgt tcgtaaggtc tttgtggacc tttacaagaa aggctggatc tatcgtggtg
     6361 agtttatcat caactgggac ccagcagctc gcacagccct ttctgatatt gaggtgattc
     6421 acaaggatgt agaaggtgcc ttctaccaca tgaattacat gctggaagat ggttcacgcg
     6481 cccttgaagt tgctacaact cgtcctgaga ctatgtttgg ggacgttgcg gttgcgatta
     6541 atccagaaga cccgcgctac aaggacttga ttggtaaaaa cgtcatcctt ccaatcgcta
     6601 ataaactcat cccaatcgtt ggagatgagc acgcagatcc tgagtttggt actggtgtcg
     6661 tgaaaatcac acctgcccac gatccaaatg acttcttggt tggccaacgt cataacttgc
     6721 cacaagtcaa cgtcatgaac gacgacggaa ctatgaatga gcttgccttt gaattttcag
     6781 gcatggatcg ttttgaagct cgtaaggcag tcgttgctaa gttggaagaa atcggtgccc
     6841 ttgtcaaaat cgaaaaacgt gtccattcag tcggtcactc agaacggaca ggtgtcgtag
     6901 ttgagccacg cttgtctact caatggttcg tcaagatgga ccaattggct aagaacgcca
     6961 ttgccaacca agacacagag gacaaggtcg aattctaccc acctcgtttc aacgatacct
     7021 tccttcaatg gatggaaaat gtccacgact gggttatctc tcgtcagctt tggtggggtc
     7081 accaaatccc tgcctggtac aatgctgatg gtgaaatgta tgtcggcgaa gaagctccag
     7141 aaggtgacgg atggactcag gacgaagacg tcttggatac ttggttcagt tctgccctct
     7201 ggccattttc aaccatgggc tggcctgaag tcgactcaga agactttaaa cgttatttcc
     7261 caacttcaac cttggtaaca ggttacgaca tcatcttctt ctgggtgtct cgtatgatct
     7321 tccagtcatt ggaattcaca ggccgtcaac cattccaaaa cgtccttatc cacggtctca
     7381 ttcgtgacga gcaaggacgc aagatgtcta agtctctcgg taacgggatt gacccaatgg
     7441 atgttatcga gaaatacggt gccgatgccc ttcgatggtt cctttcaaac ggttctgcgc
     7501 caggacaaga cgtgcgtttc tcttatgaga aaatggatgc ttcatggaac tttattaaca
     7561 agatttggaa catttctcgc tatatcctca tgaacaatgg aggtttgacg ctggatgtgg
     7621 cgcatgacaa tgtcacaaaa gttgcaacag gtgaggctgg taatgtgacg gaccgctgga
     7681 ttctccacaa tctcaacgaa accattgcaa aagttactga aaactttgat aagttcgagt
     7741 ttggtgtggc tggtcatatc ctttacaact tcatttggga agaatttgcc aactggtatg
     7801 ttgagttgac caaggaagtc ctttatagcg ataacgaaga agagaaagtc atcacacgtt
     7861 ctgttctact atacactttg gacaagatcc ttcgtctcct tcacccaatc atgccattcg
     7921 tgacagagga aatctttgga caaatctcag aaggttctat cgtgacagct gcatacccaa
     7981 ctgttaatct agcctttgaa gaccttgcgg ctcacactgg tgtggaaagt ctcaaagact
     8041 tgattcgtgc tgttcggaat gcgcgtgcgg aagtaaatgt agcaccaagc aagcctatca
     8101 ccatccttgt taagacaagc gatagcgact tggaagcctt ctttaacagc aatgtcaact
     8161 atatcaaacg ctttacaaat ccagaacact tggaaatcgc atcaaccatc cctgcacctg
     8221 aactggctat gtcaagcgtt attacaggag ccgaaatctt cttgccactg gccgatctcc
     8281 tcaatgttga agaagaacta gctcgtctcg acaaagaact cgctaaatgg caaaaagaac
     8341 tggacatggt tggtaagaaa ctctctaacg aacgcttcgt cgccaacgct aaaccagaag
     8401 ttgtccaaaa agaaaaagac aaacaagccg actaccaagc caagtatgat gtgaccgtag
     8461 cacgtattga tgagatgaag aagttggtga aataaacaca gaaacacggt gatgagccgt
     8521 gttttttggt ataatgaaat caatatctat tgatggagaa agtgatgtcc aaacaccctc
     8581 attatgaatt gttaaattta attggctacg gtcttgccaa gtttgacaag ctttttataa
     8641 aagaatttca atgctctagc aagtcggagt tttatcgcta tgtggtttct ctgggaattg
     8701 ctgaaacaac tggagttgta aaaaatagaa tggatttatt tgatccttat tttgacaata
     8761 atcgaaaagg ttggtggcag aaagctgaag tttatcgttt tcgtaaagat ttaattgata
     8821 tgatgtttgg aaatgaagat gttcatagtt atgctgaaat agttaaaatg ttacttgcca
     8881 gtgaagggaa gaaaacaggc ataaccatcg ttgaaaaacc aatagttcga actaaattca
     8941 aacgtctaca ggaaacggga atggaggctg agaattattt tatccttcat tttgataaag
     9001 aagaaaaatt ccaaggtgga cagttaaccg atgcccgtct ttatggtgat ggatatgact
     9061 ttcaggtaga tgtccaagag tattcttacc ttgccgaagt aaaaggtatc cgaaaatcta
     9121 aggggcgtgt gcgtttaact gcaaaagaat ttgaaaaagt caaggagttt caatcggatt
     9181 ttattttatc cttggtcaca aatctagatg atattccaaa gttagtgtta atcgataatc
     9241 ctttaaaaca ttttgagttt aaaaagaata ttatcaaaaa tgaaatcatt gaatatagaa
     9301 gcgtagagga tttgtattag ttccccctta acttttccag ttgaaggaac gagaagtctt
     9361 gataggtcaa cgacttaatg aactggaaat caacggtatt cgtttgacta agttttaaga
     9421 tggcgaaatc ggtattgaat ttatcagtag tgctgattat aactctttta ttatttacat
     9481 gaagtatata tatatatatc atagaaccta ttgtgaggac tttttatagt ttaagccagt
     9541 ttccaaccaa tttcgtgatt tactggtaat gaagaaaaac aattgaaagg atatttctat
     9601 gcaaccaact tacaacattg acaatccaaa cttgtcttat gaagctaagc gtgatttatg
     9661 gcggataggt tttggtctgc agaaagttga caatctagtg ccatcagctt atatggaatc
     9721 tttggctgag aaacaggctc ggggtgaact gacttatgag caggtttatg aggatgcaac
     9781 ggcttatcac catactattg atgcaagtac ggaggaggca gacttggttt ctctacgcat
     9841 tgtagaacta ttgtctcgaa gaggctttag cttcagtcct gcgaccttac ttgctattca
     9901 taaggagttg tttcaagata tatttgaacc ctcgattccg gtaggtcaat ttcgtcagac
     9961 taatatcaca aagaatgaac ctgttttgaa tggtgaaagt gttgtgtact ctgattactc
    10021 catgattcaa atgacattgg attatgattt taatcaggaa aaacaagttg catatgcgac
    10081 actaacccag gcggatatgg ttaaaaaaat ccagcatttt atttcaggaa tctggcagat
    10141 tcatccattt cgcgaaggaa acgctcggac agtaacggtc tttttgattc agtatcttcg
    10201 tgagtttggt tttgatattg ataatatacc atttcagcaa cattccaagt attttcgtga
    10261 tgccttggta ttagataatg caaagatttt acagcgacgt cctgagtttt taacagcttt
    10321 ttttgaaaat ctcttgctcg gtggtcaaaa tgatttgtct tcagaaaaaa tgtatctaga
    10381 tttagacctc gatttttcat aatccaaata ctgagtaaac attgaatttt aggaaaaaat
    10441 gaagtaaaca ttcccacaat aaaacgcata gtatcaagtg ttaaaatgta ctgcccccca
    10501 aaagttagac aattaattta tccgaaggat ttagttctgt attgcacagg gctaagtcct
    10561 tttagtttta ccttaattct cttattgttg ta
//
LOCUS       DBJKQU010000058        10341 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.058, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000058 DBJKQU010000000
VERSION     DBJKQU010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.058"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..170
                     /locus_tag="ACSUUC_001814"
     CDS             <1..170
                     /locus_tag="ACSUUC_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHQ8054975.1"
                     /translation="EYENRTVSFAISSKGENISYRVDHRILFDNISFDTSSSGVTLIT
                     GKNGTGKSTLL"
     gene            complement(268..396)
                     /locus_tag="ACSUUC_001815"
     CDS             complement(268..396)
                     /locus_tag="ACSUUC_001815"
                     /inference="COORDINATES: protein motif:HMM:NF013677.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054976.1"
                     /translation="MISSTLKIHPNSLYRWIQEYEKYEESAFPGHGSALRHTQFEM"
     gene            complement(536..1846)
                     /locus_tag="ACSUUC_001816"
     CDS             complement(536..1846)
                     /locus_tag="ACSUUC_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HHQ8054977.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2083..2955
                     /gene="nadC"
                     /locus_tag="ACSUUC_001817"
     CDS             2083..2955
                     /gene="nadC"
                     /locus_tag="ACSUUC_001817"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HHQ8054978.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3086..3932
                     /locus_tag="ACSUUC_001818"
                     /pseudo
     CDS             3086..3932
                     /locus_tag="ACSUUC_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            3993..4955
                     /locus_tag="ACSUUC_001819"
     CDS             3993..4955
                     /locus_tag="ACSUUC_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8054979.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPIESLCYE"
     gene            5132..6139
                     /gene="gap"
                     /locus_tag="ACSUUC_001820"
     CDS             5132..6139
                     /gene="gap"
                     /locus_tag="ACSUUC_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HHQ8054980.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(6207..7082)
                     /locus_tag="ACSUUC_001821"
     CDS             complement(6207..7082)
                     /locus_tag="ACSUUC_001821"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HHQ8054981.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVHWNEIVNPGDVCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTF
                     TTLSNTFEKELKKNG"
     gene            7169..9364
                     /gene="pbp2a"
                     /locus_tag="ACSUUC_001822"
     CDS             7169..9364
                     /gene="pbp2a"
                     /locus_tag="ACSUUC_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HHQ8054982.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            9417..9569
                     /gene="rpmG"
                     /locus_tag="ACSUUC_001823"
     CDS             9417..9569
                     /gene="rpmG"
                     /locus_tag="ACSUUC_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HHQ8054983.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            9579..9755
                     /gene="secE"
                     /locus_tag="ACSUUC_001824"
     CDS             9579..9755
                     /gene="secE"
                     /locus_tag="ACSUUC_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HHQ8054984.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            9810..>10341
                     /gene="nusG"
                     /locus_tag="ACSUUC_001825"
     CDS             9810..>10341
                     /gene="nusG"
                     /locus_tag="ACSUUC_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HHQ8054985.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         3236 a         1790 c         2248 g         3067 t
ORIGIN      
        1 aagagtatga aaacagaact gtttcttttg ctattagttc aaaaggagaa aatatttcgt
       61 atagggtgga tcatcgtata ttgtttgata atatttcttt tgatacttcg agttcaggcg
      121 tgacattaat tactggtaaa aatggtacag gaaagtcaac tttactatag tagattgaaa
      181 ctagaatagt acacatctac ttctaaaata ttgttagaaa tcgatttgac tatcctgatc
      241 tatttgtcct gttcttattt catttcacta catctcaaat tgagtatgac gaagtgcgct
      301 cccatgtcct gggaacgcac tttcttcata tttttcatat tcttgaatcc atcgataaag
      361 actattggga tgaattttta aagttgaact aatcattttt acaggatgag gtttacagca
      421 gagagtttga aggctttatc aaaggttttt cttggcataa tgacttttcc tcgtttccac
      481 ttaattttgt gtctacttta ttataccaag tccaccctta agttagataa taaatctaac
      541 ttaaggaagc tagaaggatg agaatccagg tggtcaagag tcccaaactt aagctgatgg
      601 ggacacccag aataatttgc tttttgaagg caaggccacg ttcctctata ttgggaagtg
      661 agagttgaat gagagaacca gctgatgaaa agggtgagat attagtagat agagcgccaa
      721 taacggtggc tgttgtgagt aagtgaatat caatctgagg attttgagca ctgatgatag
      781 caatgatggg aaagagggct ggagctacaa cggatagggt ggaactaaag agtgacatca
      841 ctccggctat cacacaaaag aacagaggta accagaaatg aggaatggat gttgtcatga
      901 ggtgccctat cagtgtgact aaacctgact tgaccgctag agacattagt aagctcatgc
      961 cgcagagcat gataattgta gcccagggaa ctttagccaa aatggcttct tgcttcccta
     1021 atttgagcct taaggcgagg cagaccatga gtattgagac aaagccaata tcaaatgttt
     1081 tttgataagt agctatccag gcgatgtttg ggaaaatgag atgcaacaag ggaaaaagcc
     1141 aaaccaaaac catgctgctg atcatgagca aggtggtttg tctttgaacc ttgctgagga
     1201 gtggtggttg gtcaatagtc aaggatgagt ttgttcttcc cttactatag tgactgtaac
     1261 aggataataa aagcaagacg atgagtgggt agataatgct gacgataaag atatgattgc
     1321 caagtgaaaa agcttgctct tcccatccca tttgcttaaa caggccttga aagacaatgc
     1381 ctgagctact ggttatcaaa ttagcccctc ctgaagctcc ccaattgacg gcttgagctc
     1441 caatcaaagg gtgtttgtcc gctttttgac agagggtaat cgctagagga cagcaaacgg
     1501 ccatagtagt gaaaaatcca gcacctaaag cagacaaaag ggttgccatc aggtataaaa
     1561 tcatgtagag ggcgttaggg taggtgcgtg tgcggtagag aatgtgttga gccaaaacat
     1621 caagagtacc gttagttatt gcaaagttat aaaagagaga gacgctaaaa atggtaaaaa
     1681 agagtgaggt tggccaaaaa tgaagaagtt ctttggggct taatcccatg agagtggttg
     1741 cgatgaggta agaaaaagca atagccagca ggccaatatt gattttggtg cggtaaccaa
     1801 ttccaatggc tagagcaatg gcgctaatca ttattaaatg aatcattgaa ttgtcctttc
     1861 agttagaata tggaaatagg ttggcaattt tggcgctcaa aagaccacct gtttcctatt
     1921 ggtacttgac tattatacac aaaaaaaata caattgtctt gacaattgta ttgacaattg
     1981 ttagaattaa aaatgaggta ttcaggcttg tgatttccta tggaagttaa tagtgattgc
     2041 ctctaatgct tacaagtgat attaaaaata gaggacctag tgatgtcaat catttcaact
     2101 gatttaaccc cttttcaaat agatgataca ttgaaagcag ccttgcgaga agatgttcat
     2161 tccgaagatt acagtaccaa tgccattttt gatcatcatg gccaagccaa ggtgtcgctt
     2221 tttgccaagg aagctggtgt tttagcgggg ctaaccgttt ttcaaagggt ttttacccta
     2281 tttgatgccg aggtgacctt ccagaatcct catcaattta aggatgggga tcgtttgact
     2341 agtggcgatt tggttttaga aatcataggc tcggtgagaa gtctcttaac atgtgaacgc
     2401 gttgccttga attttttaca acatttatca gggattgctt cgatgacagc tgcttatgta
     2461 gaagccttag gcgatgattg cattaaggta tttgatactc gaaaaactac tcctaattta
     2521 cgtctttttg agaaatatgc cgtgagagtt ggcggtggct ataatcatcg ctttaattta
     2581 tcagatgcta tcctgctaaa agacaatcac attgcggcag taggtagtgt tcaaaaggca
     2641 attgctcaag cgcgtgccta tgcccctttt gtgaaaatgg tcgaggtgga agtggaaagc
     2701 cttgctgctg ccgaagaagc tgcggcggcg ggtgctgata ttatcatgtt ggataatatg
     2761 tcattggaac agattgaaca ggccattacc ctaattgcag gacgttctcg gattgaatgt
     2821 tctggaaata ttgatatgac cactattagc cgttttcgtg gtttagcgat tgattacgtc
     2881 tccagtggta gtttaaccca tagtgctaag agtcttgatt tttccatgaa ggggttaacc
     2941 taccttgatg tctaagttgt aaaataaact aactttttaa aggatgtctt tcctctagaa
     3001 cgagttttat gtcagatagt ttaaacgcct cttcaaatat agtaaaatga accaaaaata
     3061 gtacacaatg tggtataatc tttttatggc atattcaata gattttcgta aaaaagttct
     3121 ctcttattgt gagcgaacag gtagtataac agaagcatca cacgttttcc aaatctcacg
     3181 taataccatt tatggctggt taaagctaaa agagaaaaca ggagagctaa accaccaagt
     3241 aaaaggaata aaaccaagaa aagttgatag agatagactt aaaaactatc ttactgacaa
     3301 tccagacgct tatttgactg aaatagcttc tgaatttggc tgtcatccaa ctaccatcca
     3361 ctatgcgctc aaagctatgg gctacactcg aaaaaaagaa ccacacctac tatgaacaag
     3421 acccagaaaa agtagcctta tttcttaaga attttaatag tttaaagcac ctagcacctg
     3481 tttagattga tgaaacagga atcgatactt atttttatcg agaatatggt cgctcattaa
     3541 aaggtcagtt aagaagaggc aaagtatctg gaagaagata tcagaggatt tctttggttg
     3601 caggtctaac aaatggtgag ttaatcgttc caatgactta cgaagagatg atgacgagcg
     3661 acttttttga agtatggttt cagaagtttt tcttaccaac attaaccaca ccatcggtta
     3721 ttattatgga taatgcaaga ttccatagaa tgggtaagct agaactcttg tgtgaagagt
     3781 ttgggcataa acttttacct cttcctccct actcacctga gtacaatcct attgagaaaa
     3841 catgggctca tatcaaaaag cacctcaaaa aggtattacc aagttgcaat accttttacg
     3901 aggctttttt atcctgctct tgtttcaatt gactatagtt cacggataca gttgggaaag
     3961 aagctattaa atatttggag agtccttttg ggatgaacat gtcaaatatt actatagatg
     4021 ggcaagaaat ggatctgagt caaacgatgc cttcttatgc tcaagtagtg agtctttatg
     4081 atgatacaag tatctctgtt agtaataatg agacggacaa agtgttggct ggatccctct
     4141 atactgatac aaatgaacag ggattaacga ttccaagcag tttactaaaa aattggaatg
     4201 aacagacagg aaaaaatttg acagctaatg atcttattgg caaatcagtc tcagccagca
     4261 ttgtagaaag tgctgccgaa actagtaaga ttgctcaatt tcaaacgaag attgtacgtg
     4321 taatcaatga tgaagatgac atggaggaca gcaacagttt catgctgtct catcaaatgg
     4381 aaacgatttt gaaagaggct ggatttacga aagctgtatc ttattttatc ttggaactca
     4441 aagatccatc acagacaaaa gtagtaacag aagaattaca gaaaaataag aagtatactg
     4501 tgctttctca acagagagtt cttgatattg tgattacctt tattcgtgtt attcagggat
     4561 tattgattgt gctttcatca caagctattg tggtagcagc ggttatgatt ggtatcatta
     4621 tttacatcaa tatcatgcaa cgttccaagg aaataggtgt catgaaagca gttggttatc
     4681 agaatcgtga tgtcaaagga atttttattt acgaggctat ctggattgta ggcatcgcct
     4741 tgctgctggc atttttggtt gcacaagggg tgggaagttt ggcgaatgcg attgtaagtc
     4801 acttttaccc atccatcact aaggtttttg aattaaatct tttatctgtt ttaggaactc
     4861 tagttttcgc tctattactt ggttatgtct cagcctactt cccggcgcgt aagattagta
     4921 aaatggatcc tatagaatcg ttatgctatg aatagtaagg gattccttgg tttacagtct
     4981 taaaaagaaa ctaacataga aaaacaatgg ccatacttgc aattcaactc aaatagttgt
     5041 ataataggtt tgttgaaagg tgatttgtag tgattcaagt tactcttttc acaataaaaa
     5101 tttcatgatt ttcataagga ggaaatcact aatggtagtt aaagttggta ttaacggttt
     5161 cggacgtatc ggtcgtcttg ctttccgtcg tatccaaaac gtagaaggtg ttgaagttac
     5221 acgcatcaac gaccttacag atccagttat gcttgcacac ttgttgaaat acgacacaac
     5281 tcaaggtcgt ttcgacggta ctgttgaagt taaagaaggt ggatttgaag ttaacggtaa
     5341 attcatcaaa gtttctgctg aacgtgatcc agaacaaatc gactgggcta ctgacggtgt
     5401 agaaatcgtt cttgaagcta ctggtttctt tgctaagaaa gaagcagctg aaaaacacct
     5461 taaaggtgga gctaaaaaag ttgttatcac tgctcctggt ggaaacgacg ttaaaacagt
     5521 tgtattcaac actaaccacg acgttcttga cggtactgaa acagttatct caggtgcttc
     5581 atgtactaca aactgcttgg ctccaatggc taaagctctt caagacaact ttggtgttgt
     5641 tgaaggattg atgactacta tccacgctta cactggtgac caaatgatcc ttgacggacc
     5701 acaccgtggt ggtgaccttc gccgtgctcg cgctggtgct gcaaacatcg ttcctaactc
     5761 aactggtgct gcaaaagcta tcggtcttgt aatcccagaa ttgaatggta aacttgacgg
     5821 atctgcacaa cgcgttccaa ctccaactgg atcagttact gaattggtag cagttcttga
     5881 aaagaacgtt actgttgatg aagtgaacgc agctatgaaa gcagcttcaa acgaatcata
     5941 cggttacaca gaagatccaa tcgtatcttc agatatcgta ggtatgtctt acggttcatt
     6001 gtttgacgca actcaaacta aagttcttga cgttgacggt aaacaattgg ttaaagttgt
     6061 atcatggtac gacaacgaaa tgtcatacac tgcacaactt gttcgtactc ttgaatactt
     6121 cgcaaagatt gctaaataat tcttgagttg atagaaagca aggctttgtg gtcttgcttt
     6181 tttatatgga aaaatggatg acacgatcat ccattctttt ttaattcttt ttcaaatgta
     6241 tttgaaaggg tagtgaaagt tagcctctct aaagtaagtg ggtgggtaaa ggaaagtcgg
     6301 aaggcatgaa gcataagccg gcttgtcttt gatttactat tatagagagg gtctcccagg
     6361 ataggaagat tatgatgcaa aaggtgcaca cgaatctgat gggttcgccc tgtctttagc
     6421 ttgcaatgag ccaaggaagt cttgtttgag aattgcttta atctgcttac atgcgtttca
     6481 gcatattgcc cattttttgc atcaactatt ctttttctac gatcatggcg atcacgtcca
     6541 attttgtctc tgaaaacaag ttcttttctg ttgatatttc catcaactag agcccaatat
     6601 tctctagaaa tctctttttt ctccaataag cgattgagaa tgggcaggat aaaaggattt
     6661 ttggcaaaga gaactaagcc actggtttcc atgtccagac gatgaacgac atagcaggtt
     6721 tggccaacat aggtactgac atggttaaga agggcaattt cgtttggttg attaccatgc
     6781 gttttcatcc cctctggttt gtttacaata atcaagtgtt gatcttgata aacttcctgc
     6841 actaagtctg ggttgcccca agggatcgtc ttttgggaat aatcttcctc gtcaaaagtc
     6901 aactggcaaa catctccagg atttacgatt tcgttccagt ggacttcttc ttgatttatc
     6961 aaaatatgtt tcttgattct caaaaaatga cggatttttc tagggatgag gagttgttcc
     7021 tcaagtaatt gctttaccgt catttgaggt agagaggcgg gtaatgtaaa tgtgaattgc
     7081 atacagatat tgtaacaaaa aaagccctat ttggatagga aatagctaaa ttcttgtctt
     7141 cctatgatga agatgataaa ataaacgcat gaaattagat aaattatttg agaaatttct
     7201 ttctcttttt aaaaaagaaa caagtgaact agaggactct gattctacta tcttacgtcg
     7261 ctctcgtagt gatcgaaaaa aattagccca agtaggtccg attcgaaaat tctggcgtcg
     7321 ttatcatcta acaaagatta tccttatact aggtttgagt gcaggattgc tagttggaat
     7381 ctatttgttt gctgtagcca agtcgaccaa tgtcaatgat ttgcaaaatg ccttgaaaac
     7441 tcggactctt atttttgacc gtgaagaaaa agaggctggt gccttgtctg gtcaaaaggg
     7501 aacctatgtt gagctgactg acatcagtaa aaacttgcag aatgctgtta ttgcgacaga
     7561 agaccgttct ttctataaaa atgacgggat taactatggc cgtttcttct tggctattgt
     7621 cactgctgga cgttcaggtg gtggctctac cattacccaa cagctggcta aaaacgccta
     7681 tttatcgcag gatcaaactg ttgagagaaa agcgaaagaa tttttccttg ccttagaatt
     7741 aagcaaaaaa tatagtaagg agcaaattct aaccatgtac cttaacaacg cttattttgg
     7801 aaatggtgtg tggggtgtag aagatgcgag taagaaatac tttggagttt ctgcatcaga
     7861 agtgagtctg gatcaagctg cgactctggc agggatgctc aaggggccgg aactgtataa
     7921 tcccttgaat tccgtagaag attctactaa tcggcgcgat actgtcttgc agaatatggt
     7981 tgcagcagga tatattgata aaaaccaaga aaccgaagct gctgaagttg atatgacttc
     8041 gcaattgcac gataagtatg aaggaaaaat ctcagattac cgttacccct cttattttga
     8101 tgcggtggtt aatgaagctg tttccaagta taatctaaca gaggaagaga ttgtcaataa
     8161 tggctaccgc atttacacag agctggacca aaactaccaa gcaaatatgc agattgttta
     8221 tgaaaacaca tcgctatttc cgagggcaga ggatggaacg tttgctcaat caggaagtgt
     8281 agctctcgaa ccgaaaacag ggggagttcg tggagttgtc ggtcaagttg ctgacaatga
     8341 taaaactgga ttccggaatt tcaactatgc aacccaatca aagcgtagtc ctggttctac
     8401 aattaagcct ttagttgttt atacgccagc agttgaagca ggctgggctt tgaataagca
     8461 gttggataac cataccatgc agtatgacag ctataaggtt gataactatg cagggatcaa
     8521 aacgagtcga gaagttccta tgtatcaagc cttggcagaa tcgcttaatc tacctgctgt
     8581 tgccactgtt aatgatttgg gtgtcgacaa ggcttttgag gcaggcgaaa aattcggact
     8641 caacatggaa aaggtcgacc gtgttcttgg tgtcgccttg ggaagcggtg ttgaaaccaa
     8701 ccctcttcaa atggctcaag catacgctgc ctttgcaaat gaaggtttaa tgcctgaagc
     8761 tcattttatt agtagaattg aaaatgctag tggacaagtt attgcgagtc ataaaaattc
     8821 acaaaaacgg gtgattgata agtctgtagc tgacaagatg accagtatga tgttggggac
     8881 tttcaccaac ggtaccggta ttagttcatc gcctgcagac tatattatgg cagggaaaac
     8941 tggaacaact gaagcagttt ttaatccgga gtacacaagt gaccaatggg taattggtta
     9001 tactccggat gtagtgatta gccactggct tggctttccg accactgatg aaaatcacta
     9061 tctagctggc tctacttcaa acggtgcagc tcatgtcttt agaaacattg ccaataccat
     9121 tttaccttat acgccaggaa gtacctttac ggttgaaaat gcttataagc aaaatggaat
     9181 tgcaccagcc aatacaaaaa gacaagtaca aaccaatgat aatagccaga cagatgataa
     9241 tttgtctgat attcgagggc gtgcgcaaag tctagtagat gaggctagcc gggctatctc
     9301 agatgcgaag attaaggaaa aggctcaaac aatatgggat tcgatagtca atctatttcg
     9361 ctaagatgct tgtcaaagcc tagctttctt gttataatgg ataagatgga ggcgttatgg
     9421 cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc gagaaactat tcaatcaaga
     9481 tcagcggaaa ccccaagcct acacgactag aagtaaataa attttgtaag cattgtggca
     9541 agtacactac acacagagaa acgagatagg agagagcgat gcgttttatt ggagatattt
     9601 ttagacttct taaagacaca acatggccaa ctcgcaagga aagctggaga gattttcgtt
     9661 ctatcatgga atacacagct ttctttgtag taattattta catttttgac cagttgattg
     9721 tttcaggttt gattcgattt attaacattt tttagaagat tagtggagtt aattacacta
     9781 gaaatcttct atttatgaaa ggaaatatca tggatagttt tgataaagga tggtttgttt
     9841 tacaaactta ttctggttat gaaaataagg tgaaagaaaa tctattacaa cgtgcacaaa
     9901 cctacaatat gttggataat attttacgcg ttgaaattcc aacacaaaca gtgcaagttg
     9961 aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt tccaggttat gttcttgtag
    10021 aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa cacaccaaat gttacaggat
    10081 ttgtcggatc acacgggaac agatcaaaac caactccatt attggaacaa gaaattcgtg
    10141 acattttggt atctatggga caaactgttc aagaatttga tttcgatgtt gagattggtc
    10201 aaactgtacg tattattgat ggtgcttttg cagactacac tggtaagatt acagaaattg
    10261 ataataacaa agtgaaaatg attatctcta tgtttggtaa tgacacagtt gcagaagtaa
    10321 acctaaacca aatcgcagaa t
//
LOCUS       DBJKQU010000059        10275 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.059, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000059 DBJKQU010000000
VERSION     DBJKQU010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.059"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            89..1264
                     /gene="mutY"
                     /locus_tag="ACSUUC_001826"
     CDS             89..1264
                     /gene="mutY"
                     /locus_tag="ACSUUC_001826"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HHQ8054986.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATASEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYVQANLDSSQD"
     gene            1319..2023
                     /gene="yycF"
                     /locus_tag="ACSUUC_001827"
     CDS             1319..2023
                     /gene="yycF"
                     /locus_tag="ACSUUC_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HHQ8054987.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2016..3365
                     /gene="vicK"
                     /locus_tag="ACSUUC_001828"
     CDS             2016..3365
                     /gene="vicK"
                     /locus_tag="ACSUUC_001828"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HHQ8054988.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3367..4176
                     /locus_tag="ACSUUC_001829"
     CDS             3367..4176
                     /locus_tag="ACSUUC_001829"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHQ8054989.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4267..4509
                     /gene="relB"
                     /locus_tag="ACSUUC_001830"
     CDS             4267..4509
                     /gene="relB"
                     /locus_tag="ACSUUC_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HHQ8054990.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4511..4765
                     /locus_tag="ACSUUC_001831"
     CDS             4511..4765
                     /locus_tag="ACSUUC_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE family
                     toxin"
                     /protein_id="HHQ8054991.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4812..5555
                     /locus_tag="ACSUUC_001832"
                     /pseudo
     CDS             4812..5555
                     /locus_tag="ACSUUC_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005216 - monoatomic ion channel activity
                     [Evidence IEA];
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(5856..6842)
                     /locus_tag="ACSUUC_001833"
     CDS             complement(5856..6842)
                     /locus_tag="ACSUUC_001833"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HHQ8054992.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7036..9504
                     /gene="gyrA"
                     /locus_tag="ACSUUC_001834"
     CDS             7036..9504
                     /gene="gyrA"
                     /locus_tag="ACSUUC_001834"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HHQ8054993.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9504..10247
                     /gene="srtA"
                     /locus_tag="ACSUUC_001835"
     CDS             9504..10247
                     /gene="srtA"
                     /locus_tag="ACSUUC_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HHQ8054994.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         3185 a         1747 c         2294 g         3049 t
ORIGIN      
        1 agtagataga aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag
       61 gtgaaacctt ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat
      121 gtggccggag gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa
      181 caaaagagat ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat
      241 catgcttcag cagaccaggg tggatacagt tatcccttac tacgaaagat tcctggactg
      301 gtttccaact gtcgaaagtc tggcaactgc gtctgaggag agtttactga aagcttggga
      361 gggcttgggc tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac
      421 tgactttggt ggccaatttc caaataccta tgaaggaatt tccagcttga aagggattgg
      481 accttacaca gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga
      541 tggtaatgtc atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc
      601 aagtaatcga aaaatttttc aggcaatgat ggagatcttg attaatccgg atcgtccggg
      661 tgattttaat caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag
      721 acctgaagaa agcccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg
      781 ttatccaatt aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt
      841 gaaaaattct caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg
      901 tttttggcat ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct
      961 ctttcatcag gttgcggaag aaagtgtgaa ctttggtccc agtccagaag agagtttcca
     1021 gcaggactat gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt
     1081 ttttagtcat cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga
     1141 tttttcagat agggaagttc gttggctttc accagaagaa ttcaagaatt acccacttgc
     1201 caaaccccaa caaaaaatct ggcaggctta tgtacaagcc aacttagaca gtagccaaga
     1261 ctagctattg tgtcttctga ctattttttg gtataatagt agagaaaaag gtgaacatat
     1321 gaaaaaaata ctaattgtag atgatgagaa accaatctcg gatattatca agtttaatat
     1381 gaccaaggaa ggttacgaag ttgtaactgc ttttaatggt cgtgaagcgc tagagcaatt
     1441 tgaagcagag caaccagata ttattattct ggatttgatg cttccagaaa ttgatggttt
     1501 agaagttgct aagaccattc gtaagacaag cagtgtgccc attcttatgc tttcagccaa
     1561 agatagtgaa tttgataagg ttatcggttt ggaacttggg gcagatgact atgtaacgaa
     1621 acccttctcc aatcgtgagt tgcaggcgcg tgttaaagct cttctgcgtc gttctcaacc
     1681 tatgccagta gatgggcagg aagcagatag taaacctcaa cctatccaaa ttggggattt
     1741 agaaattgtt ccagacgcct acgtggctaa aaaatatggc gaagaactag acttaaccca
     1801 tcgtgaattt gagcttttgt atcatttagc atcgcataca ggtcaagtca tcacgcgcga
     1861 acacttgctt gagactgtct ggggttatga ctattttggt gatgtccgta cagttgatgt
     1921 gactgtacga cgtctgcgtg agaagattga agatacgccc agccgaccag agtatatctt
     1981 gacgcgccgt ggtgtagggt attacatgag aaataatgct tgatttactg aaacaaacca
     2041 tttttaccag agattttatc tttatcctga ttttgttagg tttcatcctt gttgtgaccc
     2101 tcttattact ggaaaataga cgtgataata ttcagttgaa gcaaatcaat caaaaggtta
     2161 aagatttgat tgcaggagat tattccaagg ttcttgatat gcaaggtggg tctgaaatca
     2221 ccaatattac caataatttg aatgacttgt cggaggttat tcgtctcact caggaaaatc
     2281 tagaacaaga gagtaagagg ctaaatagta ttctgtttta tatgacagat ggggttcttg
     2341 cgactaaccg tcggggtcag attatcatga ttaacgatac agccaagaag caactggggt
     2401 tggttaagga agatgttctg aatagaagca ttttggaatt gctcaagata gaagaaaact
     2461 atgaattgcg tgatttgatt acccaaagtc cagaattgtt gctagattcc caagatatca
     2521 atggcgaata tttgaacctt cgagttcgct ttgccttgat acgtcgagag tctggcttta
     2581 tttcaggttt ggtggctgtt ttgcatgata cgacggagca ggagaaggaa gaacgcgaac
     2641 gaagactctt tgtttccaat gttagccatg agttacggac tcctctgact agcgtaaaat
     2701 cctatcttga agccttggat gagggggctt tgtgtgaaac tgtagcacca gactttatca
     2761 aggtttctct tgatgagacc aaccgtatga tgcgcatggt gacggatctc ctccatcttt
     2821 cacgtattga taatgctacc agtcacctag atgtggaact gattaacttc actgctttta
     2881 ttacctttat cctcaatcgt tttgacaaga tgaaaggaca ggaaaaggag aaaaaatatg
     2941 agttggtgag agattatccc atcaattcta tctggatgga aattgataca gataagatga
     3001 cgcaggttgt cgacaatatt ttaaataatg ctattaagta ttcgccagat gggggtaaaa
     3061 tcactgtcag aatgaagaca actgaagacc agatgatttt atccatttct gaccacggtt
     3121 tggggattcc taagcaggat ttaccacgta tctttgaccg tttctatcgt gtggatcgtg
     3181 ctagaagtcg tgcacaaggt ggtacaggtc taggactgtc tatcgctaaa gaaattatta
     3241 aacaacataa gggctttatt tgggccaaga gtgaatacgg caagggttca acctttacca
     3301 ttgtgctccc ttatgataag gatgcagtga aagaagaagt atgggaggat gaagtagaag
     3361 actagaatga gtgaaatagg ctttaaatac agtattttag catcgggttc cagtggaaat
     3421 tctttttatc tggaaacctc aaaaaagaag cttttagtgg atgcaggctt gtctggcaag
     3481 aaaattacca gtctgctagc tgaaattaac cgcaagccag aagacctgga tgccatcttg
     3541 attacccatg agcattcaga tcatatccat ggagtaggcg ttttggctcg caagtatggt
     3601 atggatcttt atgccaatga aaagacctgg caagctatgg aaaatagtaa atatcttggc
     3661 aaggtggatt cttcgcaaaa gcatattttt gaaatgggta aaaccaaaac ctttggagat
     3721 atcgacatcg agagttttgg tgtaagccat gatgcagtcg caccgcagtt ctatcgcttt
     3781 atgaaggatg ataagagttt tgtccttttg acagatacag gttatgtcag tgaccgtatg
     3841 gcgggcattg tcgaaaatgc ggatggctat cttatcgagg ccaaccatga tgtagagatt
     3901 ttgcgatcag gttcttacgc ttggcgactc aaacaacgaa tcctatctga ccttgggcac
     3961 ctttctaacg aggacggtgc tgaagctatg attcggacgc taggaaatcg tactaagaag
     4021 atttaccttg ggcatttatc taaggaaaat aatatcaagg aactggctca tatgaccatg
     4081 gtcaatcagc tggctcaagc tgacctggga gtcggagtag actttaaggt ttatgatacc
     4141 tcaccagata ccgcaacacc attgacagag atatagaaag aacgctgaga aggtgttctt
     4201 tttatattga ctgaacaccc aaaaagtaat acaatggtgt taccattaaa aaagggagca
     4261 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
     4321 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
     4381 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagat
     4441 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
     4501 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
     4561 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagaccc
     4621 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
     4681 taattatcga gttatcgtac aaattgtaga tgatgaatta gttgttgcta ctctagaagt
     4741 tggtcatcgg agagatattt attgaattca agctgagtaa taacagtata gaaagtaagg
     4801 agagtaaaaa tttgaagaaa aaatggttat ttgcagatta ttatgataca acaattattt
     4861 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg actgatttgg
     4921 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
     4981 gttggcgctt ttttattact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
     5041 tattggctat tctcccttta aatgctattt ttacagtgtt tcgattagga cgtatcttcc
     5101 gcttagcaag gctgacaaaa ttactgaaac tgactcgttt acttagaata attggactta
     5161 caggtaaact agaaagaaaa attagtagat tcttacgaac aaatggattg atttatatct
     5221 tgtatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
     5281 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggttatggtg
     5341 atattgttcc agtttccctt tttgggaaat ggctagcagt tttactgatg cttgtcggta
     5401 ttggaacaat agggatgcta acaagtgctt tgacgaactt ttttgtaaag gataatccag
     5461 atgaacagat aaaacttgat aaactcaaag acgaattatc gagctaaaga atattaatag
     5521 agaaacaatc tgaaaaaatc gaagaactac attgaatgat aaaagactta gttgaaaaaa
     5581 tatcataaag gtgagacaaa ataaaacttg attcgaggag aaatcaagta agttttgaca
     5641 caatagaacg catattatca ggtataaaaa cttgatacta tgcgttttat agagaaataa
     5701 aataaaatct gaacaaatca attaggaatt taaagcattt tataacaacg ttttagagta
     5761 atggggtgct atttcaactt caacctacta taatacagaa aaaaatacag aaaaaaacaa
     5821 ctccctgatg attcaaggag ttgtctatag ttaaattagt ttttagaagc ttcttggaat
     5881 tctggatttt tccatgcttc gtcaataata gcttgcaatt ctttagcaga tgcttgcatt
     5941 ttttgagttt ctgcatcgtt caatggaatg tttactggac gaacgatacc atgtgcacca
     6001 acaacagctg gttgaccgat aaagacattc tcaactccgt attgaccttc ttggaatact
     6061 gaaagtggaa gtactgcgtt ttcatcgtca aggattgctt tagtgatacg agcaagggct
     6121 actgcgatac cgtagtatgt tgcacctttt ttgttgatga ttgtgtaggc tgcatcacga
     6181 acaccttcga acaattcaat caattcagct tcttgaacat tttgagtgtc tttaaggaat
     6241 tcttcaaggt ttacaccagc gatgttagcg tgtgaccaaa cagcgaactc agagtcaccg
     6301 tgttcaccca tgatgtaggc gtgcactgaa cgagcatcca catccaattt ttcagcaagt
     6361 gcttgacgga aacgagctga gtcaagtgaa gtacctgaac cgataacgcg ttctttaggg
     6421 aaaccagaga atttccaagt tgagtaagtc aaaacgtcaa ctgggttagc agcaacaagg
     6481 aagatacctt tgaaaccaga ttcaacaact tgagttacga ttgatttgtt gatagcaagg
     6541 tttttaccta caaggtcaag acgagtttca cctggttttt gaggtgcacc tgcagtgatt
     6601 acaacaaggt cagcgtctgc acagtcagag tattgagctg catagatttt tttaggtgaa
     6661 gtgaaggcaa gggcgtgact aaggtcaagc gcatcaccaa cagctttttc atgcaattgt
     6721 ggaatttcga taattccaag ctcttgtgca attccttggt taacaagtgc aaaagcgtaa
     6781 gatgaaccta cagcaccatc accgacaagg ataacttttt tgtgttgttt agttgaagtc
     6841 attgttttaa acatctcctt aattttatta ggggattttc cctagacaac ttcattctat
     6901 cacttttaaa aaactttgtc acgaatatgc cttatagttc tcgatgtaaa cgttttagtg
     6961 gtttagaggc tgaaatagat gggaatttat ggtataatgt tgttacttac taattgtgaa
     7021 atgaggcatt tattaatgca ggataaaaat ttagtgaatg tcaatctgac aaaggagatg
     7081 aaggcaagtt ttatcgacta cgccatgagt gttatcgtag cgcgagctct tcctgatgtt
     7141 cgagatggct taaaacctgt tcaccgtcgc attctctacg gaatgaatga attgggtgtg
     7201 accccagaca aaccccataa aaaatctgct cgtattacag gggatgtcat gggtaaatat
     7261 cacccacacg gggattcctc tatttatgaa gccatggtcc gtatggctca atggtggagc
     7321 taccgttaca tgcttgtaga tggtcatggg aattttggtt ccatggatgg agatagtgct
     7381 gccgctcaac gttataccga ggcacgtatg agcaagattg ctctggaaat gcttcgtgat
     7441 atcaacaaaa atacagttga tttcgttgat aactatgatg ccaatgaacg ggaacccttg
     7501 gtcttgccag cgcgttttcc aaaccttttg gttaatggag caactggtat cgcggttggg
     7561 atggcaacca atattccacc tcataatctg ggtgaaacca ttgatgcagt gaagttggtc
     7621 atggataatc ctgaagtgac taccaaggac ttgatggaag tcttgcctgg accagatttt
     7681 ccaactggtg ctcttgtcat ggggaaatca ggtatccata aggcttatga aacaggtaaa
     7741 ggttcgattg tcctacgttc tcgtacagag attgaaacga ctaagactgg tcgtgagcgt
     7801 atcgttgtaa cagaatttcc ttacatggtc aataaaacca aggtgcatga gcatattgtt
     7861 cgcttggttc aggaaaaacg cattgagggt atcacagcag tacgtgatga gtcaaaccgt
     7921 gaaggtgttc gatttgttat tgaagtcaag cgcgacgcct cagccaatgt tattctcaat
     7981 aacctcttca aaatgaccca aatgcaaacc aattttggtt tcaatatgct cgctatccaa
     8041 aatggtatac cgaaaatttt gtctcttcgt cagattttgg atgcttatat cgagcaccaa
     8101 aaagaagtgg ttgttcgtcg tacacgtttt gataaggaaa aagcggaagc gcgcgctcat
     8161 atcttagaag gtctcttgat tgcgctagac catatcgacg aagtgattcg tatcatccgt
     8221 gctagtgaaa cggatgcgga agctcaagct gagttgatga gcaagtttaa gctttctgaa
     8281 cgtcaaagtc aagctatcct tgatatgcgt cttcgtcgtt tgacaggttt ggaacgcgat
     8341 aagattcaat ctgagtatga tgacctcttg gctctgattg cggatttagc agatattctt
     8401 gctaagcctg aacgtgtttc tcaaattatc aaagacgaat tggatgaagt taaacgtaaa
     8461 ttttctgata aacgccgtac agagttgatg gttggacaga tcttgagtct cgaggatgag
     8521 gacttgattg aagaatcgga tgtcttgatt accctttcta acagaggcta cattaagcgt
     8581 ttggatcagg acgagttcac tgctcaaaaa cgtgggggtc gtggtgtcca aggaacggga
     8641 gtgaaagatg atgactttgt tcgtgagtta gtgtcaacta gcacccatga tcatctgctc
     8701 ttcttcacaa acaagggacg tgtctatcgt cttaaaggtt atgaaattcc tgagtatggt
     8761 cggactgcca aagggctacc agtagtcaat ctcttgaaat tggatgaaga tgaaagtatt
     8821 cagacggtta tcaatgttga gtctgatcgc agtgatgatg cttatctctt ctttacaacc
     8881 cgtcacggta ttgtgaagag aactagtgtt aaggagtttg ccaatattcg tcaaaatggt
     8941 ctcaaagcgc tgaatttaaa ggatgaagat gagttaatca atgtcttgtt gacagaagga
     9001 gatatggata ttatcattgg taccaagttt ggttatgcag ttcgctttaa tcaatcagcc
     9061 gttcgtggta tgagccgtat cgccactggt gtgaaaggtg ttaaccttcg tgaaggagac
     9121 acagttgttg gtgccagctt gattactgat caagatgagg ttcttattat cacagaaaaa
     9181 ggatatggta agcgtacagt cgctactgaa tacccaacaa aaggtcgtgg tggtaaggga
     9241 atgcagacag ctaaaattac cgaaaaaaat ggcttgctgg ccggtcttat gactgttcaa
     9301 ggtgatgagg atttgatgat tatcactgat acaggtgtca tgattcgaac caatcttgcc
     9361 aatatttcac aaacaggacg tgcaactatg ggagttaaag taatgcgcct ggatcaagat
     9421 gctcagatag tgactttcac aacggttgcg gtggcagaaa aagaagaagt tgggacagaa
     9481 aacgaaacag aaggtgaagc ataatgtctc aaaaaaataa taaaaagaaa aacaagcgaa
     9541 aaaatctgct gacaaatatc ctagcaggat ttctgatatt actgtcactg gctttgattt
     9601 ttaatactca aattcgaaat attttcatag tctggaatac caataagtat caagttagcc
     9661 aggtatcaaa agaaaaatta gaagaaaatc aggatacaga aggcaatttt gactttgatt
     9721 ctgtcaaagc tatctcttcg gaagctgttc taacttctca atgggatgct caaaaattac
     9781 cagttattgg gggaattgca attcctgaat tggaaatgaa tttgccgatt tttaaaggac
     9841 ttgataatgt taatctcttc tacggagctg gtacaatgaa acgcgagcaa gtaatgggag
     9901 aaggaaatta tagtctagct agtcaccata tctttggtgt tgataatgct aataaaatgt
     9961 tattttctcc tttagataat gctaaaaatg gcatgaagat ttatctaacc gataaaaata
    10021 aagtttatac ttatgaaata cgtgaagtca aacgtgtgac accggatcgt gttgatgaag
    10081 ttgatgatag agatggggtc aatgaaatca cattagtaac ctgtgaagac cttgctgcta
    10141 cagaacgtat tattgtcaaa ggtgatttga aagaaacaaa agattattca caaacatctg
    10201 atgaaatcct aacagctttc aatcaaccat ataaacaatt ttattaatac aaatcagtga
    10261 aatcatggat ttcac
//
LOCUS       DBJKQU010000060        10222 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.060, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000060 DBJKQU010000000
VERSION     DBJKQU010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10222
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.060"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            27..1373
                     /gene="gdhA"
                     /locus_tag="ACSUUC_001836"
     CDS             27..1373
                     /gene="gdhA"
                     /locus_tag="ACSUUC_001836"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HHQ8054995.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(1869..2039)
                     /locus_tag="ACSUUC_001837"
     CDS             complement(1869..2039)
                     /locus_tag="ACSUUC_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054996.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2052..2693)
                     /locus_tag="ACSUUC_001838"
                     /pseudo
     CDS             complement(2052..2693)
                     /locus_tag="ACSUUC_001838"
                     /inference="COORDINATES: protein motif:HMM:NF012235.6"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(2818..3004)
                     /locus_tag="ACSUUC_001839"
                     /pseudo
     CDS             complement(2818..3004)
                     /locus_tag="ACSUUC_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825839.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3067..3554
                     /locus_tag="ACSUUC_001840"
                     /pseudo
     CDS             3067..3554
                     /locus_tag="ACSUUC_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3704..3850)
                     /locus_tag="ACSUUC_001841"
                     /pseudo
     CDS             complement(3704..3850)
                     /locus_tag="ACSUUC_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(3783..4184)
                     /locus_tag="ACSUUC_001842"
     CDS             complement(3783..4184)
                     /locus_tag="ACSUUC_001842"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HHQ8054997.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYCPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGASQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLTRSYPQTKDSCSLERSLGSKFG"
     gene            complement(4453..4941)
                     /locus_tag="ACSUUC_001843"
     CDS             complement(4453..4941)
                     /locus_tag="ACSUUC_001843"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006644 - phospholipid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A family protein"
                     /protein_id="HHQ8054998.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
     gene            complement(4946..6355)
                     /locus_tag="ACSUUC_001844"
     CDS             complement(4946..6355)
                     /locus_tag="ACSUUC_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8054999.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDTKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            complement(6365..8347)
                     /locus_tag="ACSUUC_001845"
     CDS             complement(6365..8347)
                     /locus_tag="ACSUUC_001845"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HHQ8055000.1"
                     /translation="MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGES
                     GCGKSVTVNTVLNLLPKNGRIAEGEITYFDEDKPIELQKLKQYGKEFRKLRGENISMI
                     FQDPMSALNPVYTIGNQITEVLHEHYDISKEEANKRAIEMLEKLGIHNAAERMNDYPH
                     QFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTSIILI
                     THDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMDKKLH
                     VIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHFFFED
                     KEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTTIGIV
                     GESGSGKSTIAKSLMKLHDITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDP
                     YASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKEALKMVNVPVEYLERYPHEFSGGQ
                     RQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGV
                     VKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKE
                     NEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            complement(8360..9211)
                     /locus_tag="ACSUUC_001846"
     CDS             complement(8360..9211)
                     /locus_tag="ACSUUC_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8055001.1"
                     /translation="MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYS
                     PDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLG
                     GIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
                     MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAG
                     LSFLGVGVPSDIPTWGNIINAAKTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRD
                     IMDPKQQ"
     gene            complement(9228..>10222)
                     /locus_tag="ACSUUC_001847"
     CDS             complement(9228..>10222)
                     /locus_tag="ACSUUC_001847"
                     /inference="COORDINATES: protein motif:HMM:NF012738.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8055002.1"
                     /translation="NHVSLTLVFSGEIKMKKYILKKVLFMIPMLLIISFLVFIALDLT
                     PADPLTYMVSPDMASSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFGYSIVNGNP
                     ISKIVGQALPATFELAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQ
                     FFFGILILNFFAIQLRILPIGGRFASGDFTFINRVEHLILPVMAMSIALVAALMRYTR
                     NSMLDVFNADYVKTARAKGVPEWKVYFKHIFRNAMRPILVLLIFRLPMLIGGSVIIES
                     VFSWPGIGSIILSSVTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY"
BASE COUNT         3352 a         1948 c         1618 g         3304 t
ORIGIN      
        1 aaatatgaca ataaaaggag aacgatatga catctgctaa agaatatatc caaagcgtgt
       61 ttgaaactgt gaaagctcgt aacgggcacg aggctgaatt cctccaagct gttgaagaat
      121 ttttcaacac tttggaacct gtatttgaaa aacaccctga gtatatcgaa gaaaatatct
      181 tggcacgtat tactgagcct gagcgcgtgg tttctttccg tgttccttgg gttgaccgtg
      241 atggaaaaat tcaagtaaac cgtggttacc gtgttcaatt caactcagct gttggaccat
      301 acaaaggtgg acttcgtttc cacccaactg taaaccaagg gatcttgaaa ttcctcggat
      361 ttgaacaaat ctttaaaaat gtcttgactg gacttcctat cggtggaggt aaaggtggat
      421 cagacttcga tcctaaaggt aaaacagatg ctgaagtgat gcgcttctgc caaagcttca
      481 tgactgaatt gcaaaaacac atcggaccat cacttgacgt acctgctggt gatatcggtg
      541 ttggtggacg tgaaattggt tacctttacg gtcaatacaa acgtcttaac caatttgatg
      601 ctggtgtctt gactggtaaa cctcttggat ttggtggtag cttgattcgt ccagaagcaa
      661 ctggttacgg tttggtttac tatactgaag aaatgctcaa agctaacggt aacagctttg
      721 ctggtaagaa agtcgttatt tcaggttctg gtaacgttgc tcaatatgct cttcaaaaag
      781 caactgaact cggtgcaact gttatttctg tttctgactc aaatggttat gtcatcgatg
      841 aaaatggtat cgacttcgat cttttggttg atgttaaaga aaaacgtcgt gctcgtttga
      901 ctgagtatgc agctgaaaaa gcaactgcaa cctaccacga aggtactgta tggacttacg
      961 ctggaaacta tgacattgct cttccatgtg ccactcaaaa cgaaatcaac ggtgaagcag
     1021 ctaaacgttt ggttgctcaa ggcgttatct gtgtatctga aggtgccaac atgccgagcg
     1081 accttgatgc catcaaagtt tacaaagaaa atggtatctt ctacggacct gcaaaagctg
     1141 ccaacgctgg tggtgtagcc gtttcagctc ttgaaatgag ccaaaacagt cttcgcctct
     1201 catggactcg tgaagaagtt gatggccgtc tcaaagacat catgacaaac atcttcaaca
     1261 cagctaaaac gacttcagaa acatacggtc ttgataaaga ctaccttgca ggagctaaca
     1321 ttgctgcctt tgaaaatgta gcaaacgcta tgattgccca aggtattgtt taagatttat
     1381 ttgcttaatc ctcaatcact acgattgggg atttttagtt gagttagaca gttgggaaat
     1441 tctaattaaa tgaaataaaa actgaacaaa ttgattgcgg aattcaaacc aatttctaac
     1501 atacttctag aaattaattt gacttttcta atcgatttgt tcatatctta tttcaattta
     1561 ctatacttac ttaacccttt ttatactcaa tgaaaatcaa agagcaaact aggaagcgag
     1621 ccgcaggctg tacttgagta cggcaaggca aagctgacgt ggtttgaaga gattttcaaa
     1681 gagtattaaa caaaaagaaa aaccgctact cctaagaata gcgatttaat catgttttta
     1741 agctactact gtagttgctc tattatttaa gtgttatgaa taacttcaat atctttaaag
     1801 ctttttgtta gatttataat ttcaactata gccatctcta ctccttagtt tacagcaaaa
     1861 aattatgctt aattcttatt gtttttgtaa acaatcagcg aacccaatac tattccattc
     1921 aacaagccta aagaaatacc atattcaact ggaaaatcta aaaaaattgc aaacactatt
     1981 ccaatcatca cccctagtga ggctattgtt aaaattacat attcattttc tttcttcatt
     2041 ttctttacac ctcatttcct ttttgtatat aagctgtagt actctccacc aagagtcatt
     2101 aagtacttat gatttcctga ctcaacaatc ttaccacctt tcattacaaa aataatatcc
     2161 gcatccttaa tcgttgacaa tctatgagct ataattattt gagtacaacc ctgactttgt
     2221 atatactttg ttattctttc ctcattaata gtgtctaatg cactagttgc ttcatctaaa
     2281 attacaatac taggattatt tattaatgca cgtgccagtg ctatccgttg cctttgccca
     2341 cctgaaatat ttgaccccat ctctgagatg atagtattaa atttcatcgg catagccatg
     2401 atttcatcat agatttgaac tgctttacaa acttcctcta tcttttgtga agtaacttcg
     2461 tgctttaaag ttatattatc aagaatactt ctgttcaata aaaacgaatc ctgtggaact
     2521 actcctaaat tttgacttaa tattttttta tctatttaat taatatttac accatcaaat
     2581 aaaacttttc ctgtatcaat cttatataat cctgatggta tttttgataa cgtacttttt
     2641 cctgaccccg attgaccgac tagtgcaatt ctctgtcctg gctcaatagt caaatttaaa
     2701 ttttctatta caggagctga gtctttggaa taagagaaag ataggtcctt aatatctatt
     2761 ctacttcaaa cgtttctaaa ctatactccg gaaaataatt taaccaataa ctatctttca
     2821 tcgtatcctc caaccagtac taagagtctg ggacaatagt ctcttatctc caaaaaaaag
     2881 cggatttgcc gttgcttttt tgcatggttg cgatagtctt ggtaaaatag aattgcccaa
     2941 taaaccattt agaaaggcta tcccatgcat attcactata acacaaatca aacaacttta
     3001 ccactagaaa tcagttcttt cttgccgcaa gaccatctcg tctttactat tgaaaaagtg
     3061 gtgaataccg atgaaaagga ggtaaaccat ctgattaaat atgccatgtt tgataaggaa
     3121 caaaagagag gctataaaca gtcagctaga aacttagcga attggcacta taatgacaag
     3181 gaggatagct atacacatcc tgatggctgg tattatcgtt ttcaccatac caaatatcag
     3241 aaaacacaga cagactttca acaagaaatc aaggtttact acgccgacga acctgaatca
     3301 gcccctcaaa agggactgta tatgaacgaa cgctatcaaa acttgaaagc taaagaatgt
     3361 caggcgcttt tatctcccca aggtagacag attttcgctc aacgcaagat tgatgtggaa
     3421 cctgtctttg ggcagataaa ggcttctttg ggttacaaga gatgtaatct gaggggcaag
     3481 tgagaattga catgggattg gtacttatgg ccaataacct cctaaaatac aataagagaa
     3541 cgactcaaaa ttaaaaagct agagttccac aattggaaat ctttagcttt tttgtgattg
     3601 agaactattt tgtcctagac tcttttgatt tttaaagaga acttaaatca ttctctaatt
     3661 aaagtaggaa gaatacacta atttagtaaa gtaaatatta aatttatttt attttaaaat
     3721 gatagtaggc tccaagcata ccagcagtgt tttgatgatg agcaaattct aatcttgtgt
     3781 tctcagccaa acttggaacc aagacttctt tcaaggctgc acgaatcttt ggtttgagga
     3841 tagcttcttg ttaatagaaa gactaaggta tcaggctcac aaaattctac cataacttga
     3901 cgacaaatgt tgcatggtgg taagtagtct tcagtttcac ctgcaacagc aatcgcaaga
     3961 atatctcctt ttctatatcc ttgagaagcc ccataaaaaa tagcactacg ttctgcacag
     4021 ttagttacac caaacgatac attttctata tttgctcctg taattacttt accatcttta
     4081 aataaaattg ctgcacctac aggaaatttg gaatacggac agtaagcatt ttttaaaact
     4141 ttttttgctt gctccattaa aacaaattta ttaattactg tcattgtttt aactccttta
     4201 ttattatatt ttactcacac taaattatag taaaatgaaa taagaacagt gcaaatcaat
     4261 caggacagtc aaatcgattt ctaacaatgt tttagaagta gagatgcact attctagtgt
     4321 aaaaaagtga gatatataat ccctcatttt atgcggaaaa tatatttggt ttctagattt
     4381 atcattatcc aatttgaatg acaataatct agaaaccaaa cgctttatta tttacgatac
     4441 taaattcaat agttatattt catcactagc atgattgtgt gcaattttac tacatgctgc
     4501 tgcggctatt gcaccaacaa tatcatctag aaatacatta caaacacctt cgtgattctc
     4561 attcaatctt tctaaaatca gtggttttaa tttatctaaa tagccataat ttgtaaaggc
     4621 aatagaacca tataaattca atatcgataa gacgattact tcatcaatcc catacaatgg
     4681 attatctttc tccataatct tttgaaattc tggagatagt ttttgtgctt cagctaactt
     4741 atctaactca attcctgtca taattacatt ctgaacttca cgttttttta gtacacgttg
     4801 aattgcatat gaagcgtcgt caagagttaa ttcagggtaa tatttttgtt gtgaaaatat
     4861 tactaacgct gccatatctt caattgtaac ttcgcgttct tttagaagtt caatacaatt
     4921 atcatataaa tcatatttca taatcttacc ccctcaatag agcattgtct gattcaattc
     4981 tgaaaatatc taaatttcct tcgattgcgt agattttagc atttttaaag ctaattttca
     5041 gtcgagtttg agttcgaggt aaaggttcgc tgaataacac ttgatagcga ccatcttcta
     5101 ttttttcaag ggaagctgta atttccattg gagtgtgatt attctcgaac aattcaattg
     5161 ttacaaagcc tccagctgca atatctgcat caaggtaaac ttgatcattg aggaaaataa
     5221 atccattggt atacaaaaca cctggatatt ctggacgttt agtatcccaa tatgcaaagt
     5281 gatctttctc aatataagca cgagacaagc ttgtttcacg gaagtttgta tgttgtccat
     5341 ttcctcccat gtagtagaaa taagtacggt caccgatagt aactggtgca gaagaataga
     5401 tacatccaca gtcaaattct ccatcaccat attgaccttt accacgagga ataagtggag
     5461 tatcagtgtt tagataatgc caaccaacat gacgataact ataagtcaat tgaaggtcca
     5521 ctgtatcgta attcttgttc agttgatctc cttcatggaa aactgaagct aaacctagta
     5581 tataatcgcc acgtttaaaa ataggcatag aataaatttg attttcataa tcacagacat
     5641 tcaaaatttc ttgaattgga gtccagttaa tgaaatcagc actcgtagat acacacggca
     5701 agcgcaatga atctctccaa gtacgagtaa ttagcacata gcgatttaat gcttcatcat
     5761 atatgatatg gttatgagtg tctgcacgtg gattgaagtt tggtacttta atgtattcat
     5821 caaagtgtag accatctttt gaaaatgcta cagcaatgaa atgaacaccg ttaccgtaat
     5881 caatctttgt aaacatttta taacgacgat tttcatctgc gtcatgttta tctagaaaaa
     5941 cagatgtacc atgtaaaaaa tgtccgataa tattattttc agttgatcct cgaaattctg
     6001 taatacctag atttggtttc acccagttaa caccatcttt actttcagca taacaaagtg
     6061 aaacaatacg cttcgcacga ggtagatatt gacgttcctt acgctcctct aaagagtatt
     6121 tttcagactc ctcatcatca gtaaatgtag aatagtagca acgataaaca cctgctaaat
     6181 catcaaagaa aacatttgga taactgttat caaaacgaat ttcccatggt ttttcctcag
     6241 tgaagaaaat ttctttatcc tttactgcct gattaacttt taattttaca ttactcattc
     6301 gataaggatt aaaaattcct ttatcaaaga aatatatttt tttatttaat ttcatattta
     6361 ccacctattc tggttttaac gctacaaaat gtgttggtga aacctgctta agatcataag
     6421 cacgaccatc ttcatcataa aattcatggt actgtgcttt aaattcaact tcattttctt
     6481 tacgttttgt tgccaatgcc tctttgaagt gataatcaac ttctggaata gcagctaata
     6541 gttttttagt gtaaatatgc attgggttat tgtagatatc ttctcgagaa ccagcttcta
     6601 caatacgtcc tttatgaata acatatagat agtcacacat gtatttcaca acacctaggt
     6661 catgagaaat aaatacataa gtcaaatctt ctttattttg gatttcaaca agataattca
     6721 aaacttgcgc ttgtacagat agatctaatg ctgaaacagg ttcatctaaa attaaaattt
     6781 ctggtttcat acaaagggca cgagcaatac ataaacgttg acgttgtccg cctgaaaatt
     6841 catgaggata acgctccaag tactcaactg gcacgtttac catcttcaag gcttctttca
     6901 tacgttcaaa gcgttcctct ttgtttccaa tattatggac aatcatcggt tcatcaaatg
     6961 aattataaat tttcttagtt gggttcaatg atgcataagg atcttggaat accatttgaa
     7021 ctttcttacg gaaatccaaa tcttccttac gtttaattcc ataaatattt tgagttttcc
     7081 cattcaaatc aatattgatt tcaccatctg taatatcatg gagtttcatt aatgatttcg
     7141 caatcgtact cttaccgctt ccagactctc ctacgatacc aatagtagtt ccttttctta
     7201 actctagaga tacgtcatca agtgctttca acggagaacc tagtggcttg aatagttgct
     7261 tcttaggata gtagtacttt ttaatatttt ttacttctaa aacaacatta cctacatgtt
     7321 tttccgctaa tgtttcttct tccttatctt cgaaaaagaa atgtttatag caagaacacc
     7381 ttacaaaatg tccgtcacct aaatcatgca attgaggttc ttcttcatga tgttcttttt
     7441 ctaaccatgg aatacgattt gcgaatctgc atcctttttc agatatttca gaaattgaag
     7501 gtacgctccc ctggataaca tgtagctttt tatccatatt ttcaggatta ggaatagatc
     7561 ttaatagaga acgagtatac gggtgtttag gttgatcaaa gatctgagct acagttccaa
     7621 cttcaacgac ttcaccagca tacatcactg caacttcatc cgcaatttga gcaataacgc
     7681 ctaaatcgtg agtaattaag ataatagaag ttccatgctc tttacgtaaa tcatcaagta
     7741 aatcaagtat ttgtgcttgg attgttacat caagggcagt tgttggttca tctgcaatta
     7801 gaatatctgg attacatacc attgcaatcg ctatgactat tctttgacgc tgccctccac
     7861 taaattggtg tggatagtca ttcatgcgtt ctgcagcatt atgaattcca agtttttcta
     7921 acatttctat agcacgttta tttgcctcct ctttagaaat gtcataatgt tcatgaagga
     7981 cttcagtaat ttgattacca attgtatata ctggattcaa tgcagacatt ggatcttgga
     8041 aaatcattga tatgttttca ccacgtaact ttcgaaattc tttaccatat tgctttaatt
     8101 tttgaagctc tatcggctta tcttcatcga aatatgtgat ttcaccttca gcaatgcgtc
     8161 catttttagg taataagttt aacactgtat tcactgttac actcttaccg catccagatt
     8221 caccaacaat ccctaaaact ttccctcttt ccaaagtgaa gtttacatct ttaataatcg
     8281 gaaatgcttt tttatcagtg atgaattcag tttttaagtt ttttacatct aaaactgttt
     8341 gattcatttt gtcaacctcc tactgttgtt tcggatccat tatatctcgt aatccatcac
     8401 caataaagtt gatagaaaga acgaaaagag taatgattga ccctggaact aaccacaacc
     8461 accaactatt tttaataaca tcggctgttt tggcagcatt tatgatattt ccccaagtag
     8521 gaatatcaga aggaacacct actcctaaga aactaagacc tgcctcactg agaatgaaac
     8581 cagcaacgtt taaagacaac gatacaatta ctggtgagat agcatttctt aaaatattat
     8641 taaagataat tcgactgtca gaaaaaccaa aagctctaca tacatccaca tatgtttctt
     8701 gtttcaaaga catgaactca ttacgaacca ttcggaacgt tgtcatccaa cccattactg
     8761 agaatacgaa gataagattg aatacacctt gtccaaaaat acttgaaagc aagagaatga
     8821 caatcatatt cgggaatgtt aagaataatt ctgctagacg aactagaaga gcatcaattt
     8881 tcccaccaaa atatccagca ataccaccaa gtacagtacc aataaccgct ccacaaatcg
     8941 ctccatacat cccgacttga attgaaactc gaccaccata taggattcga gcaaatacgt
     9001 cacgacctag tttatctgtt cccagaatgt gttttgctga aggaggacgg ttcatagatc
     9061 ctaaatcaac aacatctgga gaataggttg tcaataaagg tgctagaata catgctaata
     9121 gaattagcat gaagcatata aagccgataa aggccaattt gttattatag aattttttca
     9181 aatttctttt ccataaaggc ataggtttca taacattgac ctccttccta ataacgaata
     9241 cgtgggtcta atattgcagc cataatatct acaagtagac tagcaaataa cactacgaca
     9301 gaaatcatta atgtggtaat cataattaca ggatagtcac ctgctgttac actagatagg
     9361 atgatagaac caattccagg ccaagaaaag acactctcga taattactga tccaccaatt
     9421 aacattggta gacggaaaat caataacact aaaattggtc gcatagcatt tctaaatatg
     9481 tgtttaaaat aaactttcca ttcaggaaca ccttttgcac gagctgtttt aacataatct
     9541 gcattaaaaa catccaacat agaattacgt gtgtatctca ttaaagcagc taccaatgca
     9601 attgacatag ccattactgg tagaattaag tgttcaactc tattaataaa tgtaaaatct
     9661 ccactggcaa atctaccacc aataggtaaa attcttaact gaattgcaaa gaagtttaaa
     9721 attaaaatac caaagaaaaa ttgtggaatc gcagttccga taacagctag aaaacgagca
     9781 acattatcga taataccatt ttgtttaacg gctgatataa ccccaattac aataccaaca
     9841 attgttgaaa taattaatga cacaaaagct aattcaaaag ttgcaggcaa tgcttgtcct
     9901 acaattttgg aaattgggtt accatttaca atactgtatc caaaatcacc atggagtaat
     9961 tgccaaagcc atcttccata gcgaactaat actggatcat ttaaacctaa ttgctgtctt
    10021 agcttttcga tttgttctgc actactagcc atatctggag ataccatata tgtcaatgga
    10081 tctgctggtg ttaaatctag tgcaatgaat actaaaaagc taataatcaa caacatagga
    10141 atcatgaata atactttttt tagaatatat tttttcattt taatttctcc tgaaaaaaca
    10201 agagtgagag atacatgatt ca
//
LOCUS       DBJKQU010000061         9582 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.061, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000061 DBJKQU010000000
VERSION     DBJKQU010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9582
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.061"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(263..6964)
                     /gene="bgaA"
                     /locus_tag="ACSUUC_001848"
     CDS             complement(263..6964)
                     /gene="bgaA"
                     /locus_tag="ACSUUC_001848"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HHQ8055003.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKLEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYF
                     KLNANSKEALKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLQKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIINTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRAIIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGATGQITLTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7307..8782)
                     /locus_tag="ACSUUC_001849"
     CDS             complement(7307..8782)
                     /locus_tag="ACSUUC_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HHQ8055004.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNTAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYATKAK"
     gene            complement(8830..9135)
                     /locus_tag="ACSUUC_001850"
     CDS             complement(8830..9135)
                     /locus_tag="ACSUUC_001850"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHQ8055005.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            complement(9173..>9582)
                     /locus_tag="ACSUUC_001851"
     CDS             complement(9173..>9582)
                     /locus_tag="ACSUUC_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHQ8055006.1"
                     /translation="FDQVASLLEEREIVTPTYREALITREKSFPTGLDMEFLGKDLPN
                     VAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEVEVSLLFFIINNSSSSQTNILA
                     QLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
BASE COUNT         2579 a         2081 c         1866 g         3056 t
ORIGIN      
        1 agtaaaatga aataagaaca ggacaaatcg ataaggacag tcaaatcgat ttctaacaat
       61 gttttagaag tagaagtgta ctattctagt ttcaatccac tatacaataa gagaatgact
      121 caaaattaaa aagctagagt tccacaattg gaaatatcta gcttttttgt ggttgagaac
      181 tattttgttc cagactcttt atcttctatt taggacaaga gtttttcttt ggtctttaat
      241 gataaagaag gtatcaaaat ttctagtctt cttttttacc tttagtaact actaatcctg
      301 cactcaaacc tagaagagct aaacctgctg ctactgctgc ttggcttgac gcactacctg
      361 tatttggtaa ctgggcttta ttagtttgac tagcttcact tgaatcaatt ggttttgtat
      421 ctgctttttc tgacacttgt ggttttttag cttcttgagc tactggtttg gttccaacca
      481 agacgatgcg gtctgtcgga gcttctacca cttcacggag tttttcttcc ttacttccat
      541 caggattaat cgctgtaaag atacgttctt taccagtttt tccttcttgt tctacacgag
      601 tttcacctag atacagtgtt gaatcttttt tctcaactgt cttgtaggcc aaatcttttt
      661 caacaaattc gagttttgga agatcttctt gtacagcagc aactgtcttc tcagaaactg
      721 gtttttcctt agtcaagtgg atacggtatt ccttgacttg ttttccactt tctgaaacga
      781 ggcgaacaag tactggaagg ctatcttctc cactatctac cacagttgaa gctacttgat
      841 tgttttcttc aactgagact tttggccgtt gacctttata ggtaatttga tagtcttgac
      901 gattttcagc gaaatcagca agttcttttc catctacaag aatcttcgat tgcgtgcttt
      961 cttgaggcaa ttcacttggt gcaaggaagg tcatctcaat catcgcaaca ccgctcttat
     1021 ctgctttacg ctccatacgc catctcatag ctttggcttt gacagcttta aatgttacgt
     1081 tgatttcatc accagctgcg atgtctttat ccgcacgata aggcacagct tcccaatttt
     1141 ctggattgtt gaatggatgg tctgcgtcgt aggcttggta gtttgaatag taggttggca
     1201 cttcaaactc tggaccgaca tagcgttcta aaacgagttt agttggtgca tccgtaccac
     1261 tatctgcaaa gaagtgaagt ttggcttgcg caacagtccg ttctacaatc ttaccatttt
     1321 cacggaagat cacacccgct gatacttctg gattagaaga tggtgttgga gaccagtttg
     1381 tccaacgacg attttctgaa tgatctccgt cattgagata gtcaacgcgg tcatgagagt
     1441 ttttgtcaat atcattggtt gctgaagcaa aggcctggtt actgttttca tcatagttag
     1501 ggttatctga aagagcttcg cctagtttgt ctgtcactcg tacagtgacc tcagcaacaa
     1561 gatcactacc aaggacatgg cctcgaacgg taaattgacc tgcttttgtc agattttctg
     1621 ctggaacttc ttcccattca actgacaaat cttttgtttc gtagccgtct ttacctgtga
     1681 agtaaactgg aaccttagtc ggcaattcaa gtgcttgacc tacttgtagc aagcgagctt
     1741 gtttaaccgc agcaactggt ttatgagaaa gtaagttctt atccttagtg aagtgcagac
     1801 ggtattctcc taagatgtcg ccattttcag ctttcgcgat gacacgaact ggctcacctt
     1861 cacgaacgct tggaacgacg gtagcgagac cattgttgct aacatttgct gtgactgccg
     1921 gaacttttcc atctacagac tcaaggtagt agtctgtcaa atcagggttg aagtttgcta
     1981 agtctttgcc gtcaacttgg attcttgttt gtccttgttt ggctgccgca acttgtttcg
     2041 caaagatttg tacctctgtg atagacgttc cacgcttgtt atctgcttta accatgcgaa
     2101 tacgaatagc ataggtttca actttatcaa agctaaagtg gttcatttct ccagccttga
     2161 gttgagcagg ggcttttaga ttagtaactg gtttccagtt ggcagaatca ttaaagacat
     2221 ggtcctcatt accaacaaaa ctagggtttt taggagctgt tgggacagtc ttaccaacat
     2281 aatactcaat cacataagac ttcggtgcac caactccatg gtcttcgtgg aatccgacac
     2341 ttagattatc aacggagcgt ttgctcaaga tacctgaatc tccaaacaga acaccgactg
     2401 aagcttctgg attactacga ttccagtttg tccaacgatt ggctggttgg ttattgtagg
     2461 aaatgagctt gtcattaaca tttgaaactg ggtcgcttgg atttgaatct gaagcaaagg
     2521 caagtggcaa ttctgaaccg gtccattggt cagaaatgtt tgcaccttgc tcagtttgag
     2581 cagatacgcg aacatgaagt ttagttgtta attgagtacc ttctaagcga ccattaactg
     2641 taaagacacc ttccttagcg tattgctcta tacgaatcgc atcccatgca accttagctg
     2701 atgaaacgtg accatttgaa tcatatgtcc gaacgctttc tggtaattgt ggtgcttctg
     2761 cgattggagt tgtcacactg acttcttcaa ctgaaacgat accttctaca gagacttttg
     2821 cacgcgcttc aaggtcaatt ccttcaactt tacctagtac ttcaaatgtt tgataagagt
     2881 ctagtttttc tttcggaata gcttgccaag tgactttgtg agctttaggg aaacctttgt
     2941 catactcaac cgttactgtt gttggaagag taggtttttg atgcaaatct gtgactacat
     3001 ttacaggacg gatagattgc gcaatcttct tctcagtatt ggcttggata gtgagagtga
     3061 tttgacctgt agctccctca tattccgctt tgagagtgac tgctcctggc ttatgcaact
     3121 caagcattcc tttacgaatt gcgacttccc cttcaccact tgtagagaag gttactttat
     3181 cagctggtaa tacagcttgc gttccatctt gatagtgagc tcgaaccgac aatttgacag
     3241 tttggtcttc tttgagactg tcagcttttt ccacttgcaa gctcaagtga gcaatttttg
     3301 gcgcttcttc aaggaattga attgcatagg tttgaagagg gccaccatct ttaggctgaa
     3361 taaagatgat cgcacgcatg ccgtttgctg cgcttgcttg aagaactgtc acatcagcat
     3421 tttcagcact tgctgtgact tctggcaatt gggcaccata agatagagta cgatattgca
     3481 ttggttgtcg actagtaaga cctgttactg cttcacctcc aacagtaaca gttggcacta
     3541 caggtgctgc aggattgcct tcttctacca caagggttgc atgaattggt tgaccttcta
     3601 aataaccggt cgcttgaata cgagaacctg gaattgctaa cttagcttta tcttcttcgg
     3661 caatctccca gctatctact tcgtactctt gtacacttcc atcagtcaaa acataggaaa
     3721 cagatttgtc tacagaattc aagtcagtat ttggagcaat acgtttcaca actggtagct
     3781 ctgatttaag agcaatcact tctacacgag cttctacttc tcgtccgtca gccatacctt
     3841 tcaccgttac aataccaggc ttgctcacat ctactgaaga ccaggttaca ggacgttctg
     3901 cacggctacc atcactgtat acaaacggaa cagtggtagg catttcaggt gcctctccaa
     3961 taatggtctg tacttttggc acctctgtcc ccaaaacagt cttttcttgt ccttctttct
     4021 taccagtaaa gacagtgact tggttcgatt tcaagagatc agagtgggca gtaagggtga
     4081 atttccctgc ttgttcagtt gatttgacaa tggcaacacc tttaccatta aatgctttac
     4141 gaatccaaga accatctgct tgcgccttat agcgttcacg gctggcttgt tctccgttat
     4201 ctacaccgac cagttgacct tggccatgca attggaagcg aaccagatta ttagcagttg
     4261 gaaccacatt cccctggctg tcaacaattt catagtagat gtaagtcaag tcttttccat
     4321 ctgctgcaat cgcatggtct tccttaataa gacgaactgc cgctggctta ccagcagtcg
     4381 taatcttatc tcgagcaatt tccttgccag attcatcacg agcaattgct tccaaggtac
     4441 ctggttgata ggcaactttc cattcaagat aaagttcatt agcatttgca ccttcttggt
     4501 aagtccgccc atcgctggtt tgttttttat tgaaagtctt aagaccaaga gattttccat
     4561 tcaagaacaa ttctacacta gaagcattcg aataagcacg aactggaatc ttaccttctg
     4621 agtcagctac tttggatgct aattctttgt tttcccagtt ccagtgagga agaaggtgta
     4681 ccatcggttt cttcttaaca gaaacccatt ggctttggta gagatagaag tcatgttttg
     4741 gaatgccggc tgtatctacg ataccaaagt aagagctctt aacaggagtt tgattttggt
     4801 tgtgccatgg tgtaggttca ccaatatagt ccgtacctgt ccagataaac tgtccagcat
     4861 agccagcgtt gtcacggtca aaagtccatg aagcggttgc tgttttcccc caacccacac
     4921 gatcattccc atagtcagac tgttcataat tacgctcagg tccattgcta tgtttcaatt
     4981 cacgttcagg gcgatagtaa cttccacgtg tacgggtagc tgaagatgtt tctgatccat
     5041 aaatcaacca ttttggatgc ttagctctaa gggctttgta attatcttca gaatagttaa
     5101 atccaacagc atcgagttca tcagcaattt tctcatgccc tccgctacca ttaccgaaac
     5161 ggaatttatc tgctcccatg gtaacatagc gagtcttatc aacatccttg ataaccttga
     5221 ccaaacgttt aacagttgct aaagagtggg catcaccatt agcttcacct atttcattac
     5281 caattgacca catgaagata gcagggttgt ttttgcctct ttcgaccatg gtacgtaggt
     5341 caaaatcaga ccatttttca ccttttcgag cttctgggtg agtggcatct ttttcaaaaa
     5401 aacgtccata gtcataaggt ttcttgccac cataccaagt atcaaaagcc tcttcctgaa
     5461 cgagtaaacc tagttctgct gcgatttgca aggtttgctc actagcaggg ttgtgggttg
     5521 tacggatgga gttaactccc atctccttca tttgtttgag acggcgatat tctgctttat
     5581 agttttcttc tgctccaagc gccccatggt cgtggtgcaa ggatactcca tggaatttaa
     5641 tacgttcacc attcaaagag aaaccttcat ttggagtcca gtgatagtaa cggtaaccaa
     5701 acaaatcctt cttagcatca accaattgac cgtcacggta aacacgcgta atcaattcgt
     5761 acaaggcagg tttgtcattt aaaacggtcc agagttttgg tctttcaact tctaaaatcg
     5821 catctaggct tgttgattca tgtgctttta aggtacgact cgctgtacga actaagcctg
     5881 ttacagcatg accacctcgt tcaacgattt gatattcggc tacaagttca tggtctttgt
     5941 cgtccgtatt gatgattttg ctggtcacat gagtttcaac cttgccatgt tgttgttctt
     6001 caagttttgg tgttaaaata gttgtcccat ttttctcaac atgcacctta tctgtcactt
     6061 gtaaagtcac atcacgatag ataccacttc ctgaatacca acggctactt ggctgtttgt
     6121 tgactgcatg gacagcaatc acattctcac gaccatcttt ttgaaggtat ttggtgatat
     6181 catatgagaa ctggttataa ccatttggat aatgccccac taactgacca ttgacataaa
     6241 cttgagaatc catgtagacg ccatcaaaag taaggcgaac atttttcttg aggtcttttt
     6301 catctagttt gaaagtcttg cgataccaag cttccccacc gttgagctgt ccaccttcat
     6361 tttgtgcagg agattcatga tcgaaatcgt taaagatact ccagtcatac ggtaaatcta
     6421 attttttcca cgtagatacg tctgcatcag gtttaagggc ttccttagaa tttgcattga
     6481 gtttaaagta ccaattttga ttaaaatcca ctttcctgtc ttcaatcatt tgattcattt
     6541 cttcatttgt tacagcttta gcatcttcct tgagcggttt ttcttgactt gaagcttgtg
     6601 attctatcct tggagctttt tcttccagtt tagcagacac tttttcctct tttggagtta
     6661 cggcttcatc ttctttcttc tcagatgcaa tagcctcagt tgaactaggt tcactttgtt
     6721 ctgtcctttc aactacattt ttagtttcca aagctttatc agccttttct tctactatca
     6781 ttttttcctc tttaggtttc tcagcagtat gagtaataag tgtttcatcc gcataaacta
     6841 cagattctcc agctatattt cctcctaata gaactgcaca agtcccaatc attactgagc
     6901 aagctcccac agcaaactta cgaatgctat aaactctttt ccgattccaa tggcctttcc
     6961 ccataaaaac ctccttatat tatatttagt gcagttagct actaccaaag cccaagtggt
     7021 atacatggta tgacaaccta gtttcaacaa tttacactct gcgaaaatcc aattcaaact
     7081 tcgtcagtgt cgccttgccg tagatatgat tactgacttc gtcagtgtcg ccttgccgta
     7141 gatatgatta ctgacttcgt cagtttcatc tacaacctca aaaccatgtt ttgagctgac
     7201 ttcgtcagtc ttatctacaa cctcaaaact gtgttttgag caacctgcgg ctagcttcct
     7261 agtttgctct ttgattttca ttaagtttat attttatagg agcgcattat tttgcttttg
     7321 ttgcgtactc ttcgttacgt ttgatcattt gttttctgta ccaagcaaag ataccgatat
     7381 agaatacaag gaagactact gcaccaagga ttgctttgat atcaccagtt gtagtgttac
     7441 caattgtcca accaagaagt ttttcgattg gtccttcaag agtagagtga gtaatcaatt
     7501 gagtttggct cacaccttct gggaaggcac ctacaccttt agcaagttct gttgcaaatg
     7561 gtgcaataag tgtacctgaa agaaggaaga gtggcaacaa gagtgttccg aagataatca
     7621 tacggagcaa tttaccacga gttacaacca agagagctgg agtaacaccc atagcgatga
     7681 tacctgcaag tggcaagata ccatttccaa cttttgaaag aagcactgct tcaatcaaca
     7741 tgattggtgc aagtacgttg gcacaagccc agatttcagc acgaccagcg atgaatggcc
     7801 agtcaagacc gatattgaat ttacgtcctt gaagacgttt agtagcaacg tttgtaatac
     7861 cttgtgatag tggttctacg gctgcgatga accatgaacc gataagtgag aagagttcca
     7921 aagatacacc ggcagtcaaa ccaagagaca accatccttt gataacaaga cgccatttat
     7981 ctgcatctgc aacacctgca attggatgtg gagttcccat aataccgata acgataccaa
     8041 ggatgaaacc gatgaagaat ttagatcccc agaaaccgat tttcttgttc aatttagcag
     8101 catcaaagtc atatttatca aggcctggga agaatttttc aaaaatctta tccaaaacca
     8161 tgataactgg gttcatcatg tagttcatgt gagttgatgt cattggtgat gaacttgggg
     8221 cgttaagaag gtcatcaaat gtaggtttca tcaagtcaga gttgataatt ttcaacacac
     8281 cgacaaggac gatagctgct gtagcaataa agagtgaaac cccttgactc acaccattgt
     8341 tatcagcata ccatttaatc aagagacctg tgatagacaa gtgccagata tcaaagatat
     8401 cgacatcaag tgtatcggtt ttcttcatag caagcatcac tacgttgaca atcaacatga
     8461 tgagcaagaa gtatagtgtc caagcagaac cccaagtgat tgttgcgagt ggtgcccaac
     8521 caacgtcggt aatactcaat tggataccag tgttttcaac gaattttgca agtgatgctg
     8581 agaaagcagt gtttagcata ccgatgatag caccgatacc tgtaagagcg atggcaagtt
     8641 tgataccacc ttcaagcgct ttggagaatt tcactccaaa aagtaaagcc aatactgtca
     8701 aaatgatcaa catgatgaca ggtccaccca tttctaagat gggattgaaa acctttccga
     8761 ttaggtcaaa gattgcatcc ataacagttc ctcccttttt tatgttatat gaatgttaac
     8821 aaattagaat tagcttaatc cgtgttcttt aatagctgct tcaatattgt caaatactgg
     8881 agcgctcatt gctgggatac ggaataagat tggcccagct tcgataactg ggatacctgg
     8941 ttcaaaacca aggtctgttg cagcgattgg tgtaaagata tcgtaacctt tcataaggtc
     9001 ttcgtttaca tctttcacca tgactgcatc acagtgaaca tcataaccac ggtttgaaag
     9061 ttcttcttct agagcacttt taatttggtg acttgagtta acacctgcac cgcaggcagc
     9121 aagaatttta atcatttgga tttcctccga ttttattttt taatagacaa gattaagcgg
     9181 ttgcttcagc aatgtaagca taaagttttt ctggttcgga aatttttgat aggtcttcaa
     9241 gatgtccatt tcctgtgaaa aagtccatca actgagccag aatatttgtt tgacttgaac
     9301 ttgaattgtt aataataaag aagagtaggg atacttctac ttccttatca ggagctatca
     9361 tattgtgaaa agttactggt ttttctaatc gaacaaccac cactttctca gctagattat
     9421 gaacaatatc tgtatgagga atcgctacat ttggcaagtc ctttcctaga aattccatat
     9481 ctaaaccagt tggaaatgac ttttcacgcg tgatcaaggc ttcacgataa gttggagtga
     9541 caatttctcg ttcttccaac aagcttgcta cctgatcaaa aa
//
LOCUS       DBJKQU010000062         9038 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.062, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000062 DBJKQU010000000
VERSION     DBJKQU010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9038
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.062"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            1..662
                     /locus_tag="ACSUUC_001852"
                     /pseudo
     CDS             1..662
                     /locus_tag="ACSUUC_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(790..951)
                     /locus_tag="ACSUUC_001853"
                     /pseudo
     CDS             complement(790..951)
                     /locus_tag="ACSUUC_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884849.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(986..2068)
                     /locus_tag="ACSUUC_001854"
     CDS             complement(986..2068)
                     /locus_tag="ACSUUC_001854"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HHQ8055007.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTIFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     IIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2194..2976)
                     /gene="gatD"
                     /locus_tag="ACSUUC_001855"
     CDS             complement(2194..2976)
                     /gene="gatD"
                     /locus_tag="ACSUUC_001855"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HHQ8055008.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2976..4319)
                     /gene="murT"
                     /locus_tag="ACSUUC_001856"
     CDS             complement(2976..4319)
                     /gene="murT"
                     /locus_tag="ACSUUC_001856"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HHQ8055009.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGTTQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4418..5734)
                     /locus_tag="ACSUUC_001857"
     CDS             complement(4418..5734)
                     /locus_tag="ACSUUC_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HHQ8055010.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5928..7154
                     /locus_tag="ACSUUC_001858"
     CDS             5928..7154
                     /locus_tag="ACSUUC_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015129 - lactate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate MFS transporter"
                     /protein_id="HHQ8055011.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGILGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7353..8927
                     /locus_tag="ACSUUC_001859"
     CDS             7353..8927
                     /locus_tag="ACSUUC_001859"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HHQ8055012.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
BASE COUNT         2637 a         1734 c         1987 g         2680 t
ORIGIN      
        1 cgggttcatt tagaactaag aaatcgtggt tatctggtaa atcataaaag agttcaaggc
       61 ttgatgaaag tactcaattt acaaactaaa atgcgacaga aacgaaaata ttcttctcat
      121 aaaggagacg ttggtaagaa ggcagagaat ctcattcaag gccaatttga aggctctaaa
      181 acaatggaaa agtgctacac agatatgaca gaatttgcca ttccagcaag tactcaaaag
      241 ctttacttat caccagtttt agatggcttt aacagcgaaa ttatcgccta taatctttca
      301 acttcaccca acttagaaca agtacaaaca atgttggaac aggcattcac agagaagtac
      361 tacgagaata cgattctcca tagtgaccaa ggctggcaat atcaacacga ttcttatcat
      421 cggttcttag agagtaaggg aattcaagca tccatgtcac gcaagggaaa cagccaagac
      481 aacggtatga tggagtcctt ctttgggatt ctgaaattta tggctatgag aaaacattta
      541 aatcacttaa tcaattggaa caagctattg tagactatat tgattactac aacaataaac
      601 gaattaaggt aaaactaaaa ggacttagtc ctgtgcagta cagaactaaa tcctttggat
      661 aaattaattg tctaactttt ggggggcagt acattttaac acttgataat atgcgtttta
      721 ttgtgggaag attttcctca ttttctagtg aaattgaact ttttctaaca tcttttgata
      781 gatgacttct taatcaatta tcatttccat tgttgtttct tggggtttca tcccttgtct
      841 ttgataaaag cggagagcac cctcgttatc attccagaca cttagggtta gattattgca
      901 gccaatttct ttagcataat agcagaaaaa tgacaataaa atagccccta gatattttga
      961 aaggaaagca taggggctat atagtttaat caaaataaag caaatctttg ctggtgcttg
     1021 taaagaggtc gaagccatcc ttggtaacaa caccgcagtc ttcaatacga acaccgactt
     1081 taccagggat atagatacct ggttcaacag agaagcacat gccttcttcg atgaccatgt
     1141 cgtttccttc catgatagat gggaattcat ggacatccat accgatacca tgcccgagac
     1201 ggtggttgaa gtactcacca taaccagctt tttcgatgat ctcacgggca gcgcggtcca
     1261 cttcatgagc agtcacacct ggcttgataa agtcaagagc agcttgttgg gcttcaagag
     1321 tcaagttgta aatatctttc ttgaattggt ctggtttgcc gacagcgact gtacgagtca
     1381 tatctgacgc atagccattg accagaaccc ccaggtcaaa gaggagaaga gcatcatttt
     1441 caaccttatt agctgctgga atgccgtgtg gattcgcagc attatcacca gtcaagacca
     1501 tggtatcaaa gctcatttcg taaccttcac gtttcatggc aaagtcaatt tgtgcgatga
     1561 tatctgtctc agtcttatca agagaaatat tgtcaaaacc aacatgaaca gccttgtcag
     1621 cataaagacc tgcaaccatc attttttgta cttcatcagc tgatttgatg aggcgcatgc
     1681 gttggatacg aggagtgagg ttttcaaact cagcagtttc aaaaattgtt ttcaaaccat
     1741 ggtatttggt caagatgaga ttgtcaaact caacagcgac acgtttgaag tcaagttgtg
     1801 gaagagcatg tttgattttt tgccatggat tttcagaatc gacatagccc actactggga
     1861 aggaaacggt gctacttgca cgttctactt caagagctgg gacaaagagg agaggttcct
     1921 gatccgctag gacaaagagg aacatttggc gttcatgggg atcactgtaa aaaccagtga
     1981 ggtaattgat tgtgacgggg tcagatacga cagcgacgtc tagtttttct gattcaagat
     2041 atgttaggat ttgttgtaat ttagacatat gctaccttct ttctacccct ctattttggc
     2101 aaaaaatgag agaaaatgca agggagaagg gtaaaagaaa agacaaaaaa ctccgacaag
     2161 ataacggagt tctttgatat cattttcctt tgtttaagaa aagtcagcct tgcttttgac
     2221 gtcactgtac tcttcagcga tttcttggct gaggatatcc tcataggcag ggagttggat
     2281 atcctgacca tatttcttct tgagggcagt agtaactagg cgataagcca gattggcatt
     2341 acgagagagg ataggcccgt ggaagtagga accaaagaca ttcttataat gaaccccttc
     2401 accgaccttt tcttcgttgt ttccatttcc atagacaact tgtcccagcg gtttttggtc
     2461 atcagagagg aaggtacggc cttggtgatt ttcaaatcca tagtaggttt catcgaaatc
     2521 ttcattgtga atcttgatgt caccgataaa acggttattg gtctggttga gcgtgtagtg
     2581 tcccatgacc cctagccctt cgatacgttt tcctgaagct tcaacataat attgacccaa
     2641 tagttggaaa ccaccgcaga tagccagaac tacaccgtcg ttttggatgt agttgtcaat
     2701 gctctctttt ttagcaggta ggtcgtctgc aatgatactt tgttcaaagt cttgaccacc
     2761 accgaaaaag gcgatgtcgt agtgattttc atcaaagtca tcatggagag aaacgatgtc
     2821 aacggtcaca tgggctccca gtttttcagc cacatacttg agcatgagga tgtttccatt
     2881 gtccccgtag gtattcatga gatttccgta gaggtgggca atgttgagct gataggggta
     2941 attgccatct tttgaggaaa gtgaagtata aaccattagt tcatctcctt tctaacaatc
     3001 tgacgactag ccagcagttc acgaaattcc agcatggcag tataagttgc cagaatatag
     3061 gcatgcttgc agtcttgatt ctcaatggtc ttgagaactt gctccagatt actcgtttca
     3121 gtgattttct cagctggata gccagtcact cggaggcgac gagcgatttc agaatgacga
     3181 acaccgccag cgttgatttc aggaatgtcc atgtcagtga tttgctcaaa gtctgcatcc
     3241 cagatccagc tagtgtcaat tccatctgca tagttggcat taaggaggac agataggcta
     3301 aatggataag gtgctagttt gatcatttcg atagcttggg ttgtaccgac tggattttta
     3361 atcaagacaa gggtacattc cttgtcaccg atatgaaagg tttcttggcg tccaaagaca
     3421 gcacggctct tgtcaaatcc ctgtttgatg agttgcgaat cggcacctag gaaacgggcg
     3481 atggccacag cagctagggc gttatatata ttatagagcc cgccgatttg gataccgtat
     3541 tcttggccgt ctatgacaaa gcgagagcga ttgttggtca actcaaccaa ttttgtcaaa
     3601 cgatagtcga gatcaggacg tttacatcca caaccttcac agatataggc acccaagttt
     3661 gcataggtat tatgctcata tttgaggatg ccttggcagt caggacagag aatcccttcg
     3721 gtattgtagt gagccagttg ggctggtcct ttttccaagt caaaaccaaa atactctata
     3781 gggtttggaa tagttggctt gtagaaaagt ggactgtctc cgttaaggag aacagtagca
     3841 gttggaactt tccgaatggc atccaatatc atgttatagg tagtatagat ttcaccgaaa
     3901 cggtccatct ggtcacggaa gatattagta atgacaaaaa gactaggctg gatatagtca
     3961 cagatacgag atagactggc ttcgtcaatt tcgaggacgg caatattttt tccagtttta
     4021 gaagatttgg ctgttaggaa ggttgttgca atccctgtaa tcatgttggc accgcttggg
     4081 ttggttagaa cttgaccata aacctctttt aaaatgccga cagtgagggc agttgtcagg
     4141 gtttttccat ttgttccagt gacaacgaca atctcgtagt tcttagctag gttttgtaaa
     4201 atatctttat caaattgaag ggcgacttta cctgggagcg tacttccacg tccaagacgg
     4261 cttaaaacga agtgggaaga acgcccagca agaaggccca aagtagtttt taagttcatg
     4321 tttctattat atcacaaaag agggaaaaga cagatttggt gtttcgtaga agtaaaaaca
     4381 gcccaaagag ggctgtcagt taagatgaga tttcaactta aatcgcaaac aagtcattca
     4441 agttctcagc caaggttggg tgagtgaaga tttgttttgt gaagtaagtg taaggaatct
     4501 tgttgtccat agcaacagta atgatgttga tgatttcttg agaaccttct gagaagatgc
     4561 ttgcaccaag aatttctttt gtttcagtat taacaacagc tttgaaagct ccgcgaaggt
     4621 ctccatttac gtgaccacga ggcatggctg caacagggat ttctttcact gcgtatggaa
     4681 gtttcaaatc agctgcttgg ctttcagtca aaccaacttg tgaaagtgca ggtgtgatga
     4741 acatagtatt tggcacattg agacggtcct caagtgtgta gctgccatct ccagcaaggt
     4801 agctgtaaac aacacggaag tcatcaagtg aaatgtaagt aaattgaaga ccaccgttga
     4861 catctccaac tgcaaagaca ccaggaacgt ttgtttgaca gtgtttatct actttaatag
     4921 cgccacgttc agttagttca atatctgtat tttcaagttg aagtggttct acatttggtt
     4981 tgcgtccagt tgcgtagaga agggcgtcga aacggtaagt ttcgtcttca gttacgacaa
     5041 gcacttggtc accgtcgttt ttaatttcag tagtatggat attttgaagc aattcaatac
     5101 cgtcttcttc catgtattgt ttagcaagag ctgcgatgga aggttctgca cgaggtagga
     5161 atgtatccaa ggcatctagg actgtaacct tgcttcctag tttattgtaa aggccagcaa
     5221 attcaagacc gatatttccg ccaccaagga ctccaagttt ttcaggcaat ttatccaagc
     5281 tttggatacc tgttgagtca aagacgtttt tgcttgtagc aagtccaggg attggcaaga
     5341 cgtttgaaac agcaccagtg ttgatgacga tagtttcagc agtcaattct tgtttttcat
     5401 caccagcttg gatttcgatg actttatttg aaaggaagtg agcttcagca tcaaagatat
     5461 tgacgccagt accagcaaca gtcgtatagt ttttaccgtt gaggcgacca gtgatcgtgt
     5521 ttttggtagc aatgacttct tcaaaagaca agtctttctc agcagcaacc agcaaagttt
     5581 tagttgggat acaaccgatg ttgatacaag ttccaccgta catagctttg ctacgttcaa
     5641 cgagggcaac ttttttgcca gctgaagcca atttacctgc tagtgtttta ccagctttac
     5701 caaatccgat aacgattaaa tcataagtta acatttagag ttcctcctat tcgcatttca
     5761 ttctagcaca agaaaaaaac ttttgcacaa ttctgctacg gaaaagacag aaaaagataa
     5821 aaacgctttc cagacaaaaa actagtaatt ttttgacaag cttgataaac taaaatccta
     5881 tctattttta tataagatag aaaaaatgtt cgaaaatagg aggttttatg aaatcgaatc
     5941 gttatattat tgcctttgct ggggtcattt tacacttaat gctgggttcg acttatgctt
     6001 ggagtgttta tcgtaaccct attattgaaa aaacgggatg ggatcaggct tctgttgcct
     6061 ttgcctttag tctagcaatc ttttgtttgg gcttatcggc tgcatttatg gggcgtttgg
     6121 tagaaaaatt tggtccgaga gtcatgggga gtctatctgc ttttctatac gcaggtggaa
     6181 atatcttaac aggatttgca atagaccgtc aggaactgtg gttgttgtat ctagcttatg
     6241 gcattttagg tgggcttggt ttgggagcag gctatattac ccctgtgtca acgattataa
     6301 aatggtttcc tgataaacgt ggtctcgcaa caggtttagc gattatgggg tttggttttg
     6361 cttctttatt gactagtccc atagcgcaac atctcatcgc aggggtaggg cttgtagaaa
     6421 ctttttatat tttaggtgca agttacttta ttatcatgct cctagcttca caattcatta
     6481 agcgtccaaa tgagcaagag cttgcaattt tatctgcttc agggaaagaa aaaacagact
     6541 ctctgacgca agggatgact gcaaatcagg ctctaaaaag caatcggttt tatatgcttt
     6601 ggattatttt ctttatcaac atagcttgtg gtttaggctt aatttcagcg gcatcgccaa
     6661 tggcacagga gatggctggc ttgtctacaa gtcatgcagc agtaatggtg ggtattttgg
     6721 ggattttcaa tggatttggt cgcttgctct gggcgagttt gtctgactat atcggtcgcc
     6781 ctctaacctt tagtatatta ctgcttgtca atcttttctt ttctctctca ctttggctct
     6841 ttacagattc cgttttattt gtagttgcta tgtctatttt gatgacttgc tatggagctg
     6901 gtttttcttt gattccagct tatctcagtg atatttttgg aaccaaggaa ttggccgctc
     6961 tgcatggtta tattttaaca gcttgggcaa tggctggttt agcgggacct attttattag
     7021 cagagactta taaaatggct cattcgtaca cacaaacctt gttcgttttt ctcattttat
     7081 acagtatcgc cttggctttg tcttattatc taggtcgttc aatcaaaaaa gaaagtcaaa
     7141 aaccgcttac atgattttct gtagaaatgg ggctatcttt tgctctggtc ttgtgttata
     7201 ctagataggt tgcaaagaaa acagtacttt tcttttgtgg aaaagaagca acacgatttt
     7261 atatctagtt atatgaaaat acgtcataaa aagaaaagta taaactaagc cctatagggt
     7321 ggcttcgcac cacctttaga aagaagaata acgtgaaatt taatgaatta aacttgtctg
     7381 ctgatttgct agcagaaatt gaaaaagctg gttttgtaga agctagtcct atccaagaac
     7441 aaactattcc tttggccctt gaaggcaagg atgttatcgg tcaagctcag actggtacag
     7501 gaaaaactgc agcctttggc ttgcctaccc ttgaaaaaat ccgtacagaa gaagcgacta
     7561 tccaagcttt ggtcatcgct ccaactcgtg aactagctgt ccaaagtcaa gaagaactct
     7621 tccgctttgg tcgtagtaag ggagtcaaag tccgttcagt atatggcgga tcaagcattg
     7681 aaaaacaaat taaggctctt aaatctggtg cccatatcgt ggtgggaact ccaggtcgcc
     7741 tcttggactt gattaaacgc aaggccttga aattacaaga cattgaaacc cttatccttg
     7801 acgaagcgga tgaaatgctt aacatgggct tccttgaaga catcgaagcc attatttccc
     7861 gtgtacctga gaaccgtcaa actttgcttt tctcagcaac tatgccagat gccatcaaac
     7921 gtatcggtgt tcagtttatg aaagcccctg aacatgtcaa gattgcggct aaggaattga
     7981 caacagaatt ggttgaccag tactatatcc gtgttaagga acaagaaaaa tttgacacca
     8041 tgactcgtct catggatgtg gcacaaccag aactcgctat tgtatttggt cgtaccaaac
     8101 gccgtgtgga tgaattgact cgtggtttga aaattcgtgg cttccgtgca gaaggaattc
     8161 atggcgacct agaccaaaac aaacgtcttc gtgtccttcg tgactttaaa aatggcaatc
     8221 ttgatgtttt ggttgcgaca gacgttgcag cgcgtggttt ggatatttca ggtgtgaccc
     8281 atgtctacaa ctacgatatt ccacaagatc ctgagagtta tgttcaccgt atcggtcgta
     8341 caggtcgtgc tggtaagtca ggtcaatcta ttacttttgt tgctccaaac gaaatgggtt
     8401 accttcaaat cattgaaaac ttgactaaga aacgcatgaa aggtctcaaa cctgcaagtg
     8461 tagaagaatc cttccaatca aaaaaacagg tagctctcaa gaaaatcgaa cgtgattttg
     8521 cagatgaaac cattcgtgcc aactttgaga aatttggtaa ggatgctcgc aaattggctg
     8581 ctgagtttac tccagaagaa ttggcaatgt atatcttgag tctgacagtc caagacccag
     8641 atagccttcc agaagtggag attgcacgtg aaaaaccact accgtttaaa ccatcaggta
     8701 atggtttcgg tggtaaagct aagggaggtc gtggaggccg tcgtggggac gaccgtcgag
     8761 agcgtgatcg ccgtggcaat ggtcgccgtg atgagttcaa aaaaggaagt cgtggcaacg
     8821 atcgttttga taaggaaaaa cgttaccgta aggataataa aaaaccacgc aatactttaa
     8881 gcgaaaagca aacaggcttt gttattcgta acaagggcga taaataagaa aaagcggttc
     8941 aaaatgaatc gcttttttat ataaggagac cgaatgtgaa aagacaaata aaattattat
     9001 attatctttt ataatgttat gatacacaaa aataggca
//
LOCUS       DBJKQU010000063         8535 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.063, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000063 DBJKQU010000000
VERSION     DBJKQU010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.063"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            15..1016
                     /locus_tag="ACSUUC_001860"
     CDS             15..1016
                     /locus_tag="ACSUUC_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHQ8055013.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    1228..1457
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    1860..2085
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2157..3518
                     /gene="trpE"
                     /locus_tag="ACSUUC_001861"
     CDS             2157..3518
                     /gene="trpE"
                     /locus_tag="ACSUUC_001861"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - L-tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HHQ8055014.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPVPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSDYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3515..4081
                     /locus_tag="ACSUUC_001862"
     CDS             3515..4081
                     /locus_tag="ACSUUC_001862"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - L-tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HHQ8055015.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            4092..5096
                     /gene="trpD"
                     /locus_tag="ACSUUC_001863"
     CDS             4092..5096
                     /gene="trpD"
                     /locus_tag="ACSUUC_001863"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - L-tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HHQ8055016.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNLGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5093..5860
                     /gene="trpC"
                     /locus_tag="ACSUUC_001864"
     CDS             5093..5860
                     /gene="trpC"
                     /locus_tag="ACSUUC_001864"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - L-tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HHQ8055017.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            5847..6446
                     /locus_tag="ACSUUC_001865"
     CDS             5847..6446
                     /locus_tag="ACSUUC_001865"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HHQ8055018.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKDGISGTK"
     gene            6424..7647
                     /gene="trpB"
                     /locus_tag="ACSUUC_001866"
     CDS             6424..7647
                     /gene="trpB"
                     /locus_tag="ACSUUC_001866"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - L-tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HHQ8055019.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGREIPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            7640..8416
                     /gene="trpA"
                     /locus_tag="ACSUUC_001867"
     CDS             7640..8416
                     /gene="trpA"
                     /locus_tag="ACSUUC_001867"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - L-tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HHQ8055020.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIKTEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDITLIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(8388..>8535)
                     /locus_tag="ACSUUC_001868"
     CDS             complement(8388..>8535)
                     /locus_tag="ACSUUC_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HHQ8055021.1"
                     /translation="FRNRSVIFQIQFTIKLAFLLQKKKERLPFVPFLLLATCLIIFGK
                     LLLV"
BASE COUNT         2529 a         1591 c         2061 g         2354 t
ORIGIN      
        1 aatggaggac tgaaatgaaa aatataaatg ggaaaaaggt aactatttat gatattgcac
       61 gtttatcagg tttttctcca aaaacagttt cacgagttat taatggtgga gtaaatgtta
      121 aagaagaaac ttatcaagcg attcaaaaag ttatagagga attgtcgtat attccaaatg
      181 cgtatgcaaa aaatttaact aaaaaagaag ctataaatat attgatttct gtaaaaaaaa
      241 tcgactcttt tcctttaatt tggtttcata cgctgttaga taaagtgtta cggacgtgta
      301 aagaatttgg tgttaatgct atagttgagt actttggaga ggaggataca attagtaatt
      361 caattatatc aagcacaggt agcctagtag atggtgttat tgttttttat gaaagtgtag
      421 atgatatcag aattcagtat ttaaagaaga accatatgcc ttttcttgtt ttcggtgaat
      481 ctcaaacgtc tggagtagtc tatgtatcta ataataattt tcaagctact tatgatatga
      541 tgaaagctgt aactgaagaa aaatttaaaa atatgtggtt gcttatggga ggagaatccc
      601 atgttaataa ggatcgtgaa agaggtgtgc gttcttttct gaatgataaa aattacttta
      661 tggatttaaa agtcatttat ggcttatcta caattgattc agtttattct tatgcaatgc
      721 agcacttgac tacccaaaat tatccggaca ttatttttgt ttcaggagat gaaaaggttc
      781 agggcttgat tcgtgcgtgc tatgagaaag gaattcttat tccagatgat atttctatca
      841 ttggatttga taatattcct atttctcagt attatactcc agctttgtct acaattgctc
      901 ccaattatgt taaattggct aaagaaatga tagaaggtgt tttagcaatt attaaagggg
      961 aaagtgtcac atctgttgaa gtttctccta aatttgttag gagacagagt ttctagtatt
     1021 gtttaattct tgaaaatcct agtggaaaag atggagtgtt ctaaaataag ttctgtttag
     1081 cctccattca gtttctattg agttggatcc aatttctaac aagtgggaca tgttcatgtt
     1141 cgatctaagg aagacatggt cacattcgaa tgatattttc aaaaaaatcg taaaaaagtc
     1201 ttgacaaaga aaaaacaaag tattaaaata agttcaacaa atcagaaaag taactatttt
     1261 tgatcttcag ggagcctgtg gtgattgtga ataggtggtt ggaagtagtg aaagtgggct
     1321 gattttgaaa atgaatttga aacaatgaaa attcggtgcg cacaccttac agtgcagctt
     1381 gttgttaaac aaggcagaga tgtaaaggga tagtcccttt ataattgagg tggcaccgcg
     1441 ttaccaacgc cctcacacgg aagtatattc tgtgtgtggg cttttttcta tccgtcgttt
     1501 ggtttatctt ttattagggc cttaagtcgc tttgatgaac ttgagttcta tctacagctc
     1561 cttgcctact actaaaagca aacaaaaagg ctggactaat acgaaaaaag ctagtaatac
     1621 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgctcaaa acactgtttt
     1681 gaggttgtgg atagaactga cgaagtcagt aaccatacct acggcaaggc gacgttgacg
     1741 cggtttgaag agattttcga agagtataaa ggtgtaccga gatgaacatc tcttcatcaa
     1801 tgtctctggt cgtggaggca aggacctagc tgcgattgca gattactaga agctaaaaaa
     1861 taatagatgg aaaaattaca gtcttttctc tcacagagag cttgtggttg ctgaaaacaa
     1921 gcagagaaag ctgtaaagtt gggttcatct gaaacgagag aagaaaacat cattctcaag
     1981 ggagtgccct ttatcgcaca gcctgttaca ggaggtatct gagacaggaa tgagagatag
     2041 gagaaatcct ataattgagg tggcaccgcg aatttcgtcc tcacgcaagt tattttgcgt
     2101 ggggattttt catacagtcg ccacgaacta gaattagaac tgaaagggaa attacaatgg
     2161 aacgaatcat tcatggagat gtcttatcac caatcttggc ttatatgcgc ttaaaggggc
     2221 aacataaggt tattttagag agtattccga gagacaagga aacggctcgt ttttctatcc
     2281 tagcctataa tccagttttt gagattaagt ttgaaaatgg agttctctat caaaatggtc
     2341 aagtgattga tcgggatccc ttggatttcc tttatgaagt gattcataag agtcagcacc
     2401 actcagagct cccttttggt ggtggagcca ttggttttgt gggttacgat atgatttcgc
     2461 tttatgaaga aattggtcaa atccctgagg atacaattgg gacgccagac atgcatttct
     2521 ttgtctatga gagctatatg gtctttgacc acaagaagga gaagatacat gtcatagagg
     2581 atgcacttta tagtgagcgc agtcaagagg ccttggaaaa atcattgaac caagtgcttg
     2641 aggaattacg cattcctgtt ccaaatgaat ttgaagactt ggatctatct ccgttagact
     2701 tcaaaccgca tatcgctcca cataagtttg agggaatggt agaaacagct cgtgacttga
     2761 ttcgtaacgg agatatgttc caatgtgtac tcagccagcg tttctcagca gaagttactg
     2821 gaaatccatt tgacttctac agaaatctcc gcgtgactaa tccttctgat tacctttatt
     2881 tctatgattt tggggattat caaatcatcg gagctagtcc agaaagtttg gtttctgtca
     2941 aaaatggcat cgtgacaacc aatccgattg cagggacgcg accaagaggg gctacggatg
     3001 aagaagacaa gaccttggcg actgacctcc tctctgatga gaaggaaaca gcagaacatc
     3061 gaatgttggt agacttgggg cgtaacgata ttggccgcat ctctgaaacg gccagtgtcc
     3121 aagttactaa gtatatgaag gtggagctct tccgctacgt catgcatttg accagtgtgg
     3181 tcaaggggcg tttgcttgca gaactcactg ctatggatgc cttgaaagca acgcttcctg
     3241 ctggaaccgt ttctggagca ccaaaaattc gagcgatgag acgcatctat gaactggaaa
     3301 cggaaaaacg gggcgtatat gcaggagcaa tcggctactt gtctgcgacg ggtgatatgg
     3361 atttggccat tgccatccga accatgattc tcaaaaatca aagagcctat gtgcaggctg
     3421 gggcagggat tgtctacgac tctatcgccc aaaacgaata ccaagaaacc attaacaaag
     3481 caaaatctat gactagaatt ggagaactaa gaccatgatt ttattgattg acaactatga
     3541 ttcttttacc tataacttgg cccaatacat tgggaatttt gcagaagttc aggttttgag
     3601 aaatgatgat tccaagctgt atgaagaagc tgaaaaagca gatggtctgg tcttttctcc
     3661 tggtcctggt tggccagttg atgctggaaa gatggaagac atgattcgtg attttgcagg
     3721 caagaagccg attctaggga tttgtttggg ccaccaagcc attgcagaag tctttggtgg
     3781 taagctaggt ttggctccaa aagtcatgca tgggaaacag agcaatatca actttgaagc
     3841 gccatctgtt ttgtatcaag gtattgagga tggccgtgcg gtcatgcgtt atcacagtat
     3901 tttgattgag gaaatgccag aagactttga agtgacagct cgttcgactg atgaccaagc
     3961 catcatgggg attcaacata aaaacctacc gatttatggc ttccagtacc atccagagag
     4021 cattggaacg ccagacggct tgtcttctat tcggaatttt atcgaggagg ttgtaaagtg
     4081 aggaaactag gatgaaagag attattgaaa aactagcaaa atttgaaaat ttatcaggtg
     4141 tggaaatgac ggatgtcatt gagcgtatcg taactgggcg tgtaactgaa gcgcagattg
     4201 cttctctcct cttagctctt aagatgaagg gggaaacacc tgaagaacgc acagccattg
     4261 cccaagtcat gagaggacat gcccagcata ttccaactga gattcatgat gccatggata
     4321 actgtggtac aggtggggac aagtctttca gttttaatat ttccacaact gcagcctttg
     4381 tcttggctgg tggcggtatt cacatggcca agcatggtaa ccgctcgatt tcttctaaat
     4441 ctggttccgc agatgtcctc gaagccttgg gaatcaatct tgatctcaaa ccagctgaac
     4501 taggtaaggt ctttgataaa actggaatcg tctttctctt cgctaaaaat atgcacccag
     4561 ctatgaaata catcatgcca gctcgtttgg aattgggaat tccaacgatt atgaacttga
     4621 ctggtccact gattcatcca atggctttag aaacacagct tcttggaatt agtcgtccag
     4681 aactcctaga aagtacagct caggttttga aaaatctggg tcgcaaacgt gccatcgtgg
     4741 ttgctggacc agaagggttg gatgaagctg gcttgaacgg aacaaccaag attgcacttc
     4801 ttgaaaatgg cgaaatcagc ttgtcaagct ttactccaga ggatttggga atggaaggct
     4861 atgctatgga agatattcgt ggtgggaatg ctcaggaaaa tgcagaaatt ttgcttagcg
     4921 ttctgaaaaa cgaagcaagt ccattcttgg aaacgacagt cttgaatgct ggtcttggtt
     4981 tctatgctaa tggtaagatt gatagcatca aggaaggagt tgccttggcc cgtcaagtga
     5041 ttgctagagg caaggccctt gaaaaactca gactgttaca ggagtaccaa aaatgagtca
     5101 ggaattttta gcacgaatct tagagcagaa ggcgcgtgag gtggagcaga tgaagctgga
     5161 gcaaatccag cctctgcgcc agacctatcg cttggcagaa tttttgaaga atcatcagga
     5221 ccgcttgcag gtaatcgctg aggtcaagaa agctagccct agtttgggag atatcaatct
     5281 cgatgtggat attgtgcaac aggcccagac ttatgaagaa aacggagcag tgatgatttc
     5341 ggtgttgaca gatgaggttt tctttaaagg gcatttggat tatctacggg aaatttccag
     5401 tcaggtagag attccgacgc tcaacaaaga ctttatcata gatgaaaagc aaatcatccg
     5461 cgctcgcaat gcaggtgcga cagttatctt gcttattgtg gcagccttgt ccgaagaacg
     5521 cctcaaggaa ctgtatgact acgcgacaga gcttggtctg gaagtcttag tggagactca
     5581 caatctagct gaactagagg tagcccacag acttggtgct gagattatcg gggtcaacaa
     5641 ccgcaacttg actacctttg aggtcgactt gcagaccagt gtagatttag ccccttactt
     5701 tgaggaaggt cgctattaca tttctgaatc tgccattttc acagggcagg atgcggaacg
     5761 actagcccca tactttaacg gaattttggt agggacagct cttatgcagg cagaaaatgt
     5821 ggcccagaga atcaaggagt tgcagattga caaaggttaa aatttgtgga ctatcgacca
     5881 aagaagcggt ggaaacagcc gtttcagcag gagccgacta tatcggtttt gtctttgcac
     5941 ctagtaaaag acaggtgact ttagaagagg cagctgagtt ggcaaagctt attcctgcag
     6001 atgtgaaaaa ggttggagta tttgtttcac caagtcgggt agaactgctg gaagcgattg
     6061 acaaagttgg cttggacttg gttcaagttc acggtcaggt ggcagatgat ttatttgaga
     6121 atttgccttg tgccagtatt caggctgtgc aggtagatgg aaatgggcat gtccccaatt
     6181 ctcaggcaga ttatctactc tttgatgccc ctgtggcagg aagtggccag tcctttgatt
     6241 ggggtcaact ggatacgact ggactagcac agcccttctt tatcgcaggt ggccttaatg
     6301 aagataatgt agtaaaagca attcaacatt ttactcccta tgcagtagat gtatcgagtg
     6361 gagtggagac agatggacaa aaagatcatg aaaagattag aagatttata gagagggtaa
     6421 aggatggcat atcaggaacc aaataaagat ggattttacg gaaaattcgg cggacgtttt
     6481 gtcccagaaa cattgatgac agcagttttg gagttggaga aggcctaccg tgaaagtcag
     6541 gcagacccaa gtttccaaga ggaattaaac caacttttgc gccagtatgt gggacgtgaa
     6601 attccccttt actacgcaaa aaatttgacc cagcatatcg gcggagccaa gatttatctc
     6661 aaacgggaag accttaacca tacaggagcc cacaagatta acaatgcctt aggacaagtt
     6721 tggcttgcca aacgcatggg taaaaagaaa attatcgcag aaacgggtgc tggtcagcac
     6781 ggtgtggcaa ctgcaactgc tgcggccctc tttaacatgg aatgtaccat ctacatgggt
     6841 gaggaagatg tcaaacgcca agccctcaat gtcttccgta tggagctttt gggagctaag
     6901 gtcgaggccg tgacagatgg ttcgcgcgtg ctcaaggatg cggtcaatgc agcccttcgt
     6961 tcatgggtgg ctaatatcga cgatacccac tatatccttg gttctgcctt ggggcctcat
     7021 ccatttccag aaatcgttcg tgacttccaa agtgtcatcg gtcgagaggc taaacaacag
     7081 taccgtgact tgacaggtcg agatctgcca gatgccctag tagcctgtgt tggtggtgga
     7141 tctaatgcta ttgggctctt ccatcccttt gtagaagatg agtcagtagc catgtatgga
     7201 gctgaagcgg ctgggcttgg tgtggataca gagcaccacg ctgctacctt gaccaagggt
     7261 cgtccgggtg ttcttcacgg ttctctcatg gatgtgctcc aagatgccca tggtcaaatt
     7321 cttgaagcct tctctatctc agcaggtttg gactatcctg gtatcggtcc agagcattct
     7381 cactaccacg atatcaaacg tgccagctat gtccctgtga cagacgaaga agctttggaa
     7441 ggatttcaac tcttgtctcg tgtggaaggg attatcccag ccttggaatc tagccatgct
     7501 atcgcttttg cggtgaaatt ggccaaagaa cttggaccag aaaagtctat gattgtatgc
     7561 ctatcaggtc gtggggacaa ggatgtggtt caagtcaaag accgcttgga agcagatgca
     7621 gcaaagaagg gagaagctca tgcctaagac actaacagaa aaattaaatg ctataaaagc
     7681 agctggaaaa ggaatttttg ttccctatat catggctgga gaccacgaga aaggtttgga
     7741 tggactagga gaaacaatcc actttttaga agatttgggt gtctctgcaa ttgaagtggg
     7801 tattcccttt tcagaccctg ttgcagatgg acctgttatc gaagaagctg gcttgcgcag
     7861 tttagcccac gggacctcta cccaggcttt agttgaaacc ttgaaaacca ttaaaacaga
     7921 gattccactg gtcatcatga cctacttcaa ccccctcttt cagtacggtg tggagaactt
     7981 tgtcaaagat ctggctgata cagctgtgaa gggcttgatt atcccagact tgcctcatga
     8041 acatgccaac tttgtagaac catttttggc agatacagat atcaccttga ttcctttagt
     8101 aagcttgacc acaggaattg agcgccagaa agagttgatt gaaggggcgg agggattcgt
     8161 ctatgccgtt gccatcaatg gagtgacagg gaaatcaggc aattaccgtg cagatttgga
     8221 caagcacttg gcgcaacttc atcaagtggc cgacatccca gtcttgacag gttttggtgt
     8281 atctagtcaa gccgatctgg aacgcttcaa tgcggtgtca gatggtgtta tcgtcggttc
     8341 gaaaatagta aaagctctcc accaaggaga gccgattcag gactttatca aacaagcagt
     8401 agcttaccaa aaataatcaa acaagtagca agtaagagga aaggaacgaa aggaagtctt
     8461 tcctttttct tttgcaggag aaaggctagt tttatagtaa attgaatctg gaatattaca
     8521 ctacggttcc taaaa
//
LOCUS       DBJKQU010000064         7947 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.064, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000064 DBJKQU010000000
VERSION     DBJKQU010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7947
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.064"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..1419
                     /gene="galT"
                     /locus_tag="ACSUUC_001869"
     CDS             <1..1419
                     /gene="galT"
                     /locus_tag="ACSUUC_001869"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HHQ8055022.1"
                     /translation="EIDKIYVKNRVLALIGEEGTDRISDENDLKQIKDYLVEIALKNG
                     KIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISPQEAVEEFYKLSKDSDYIKT
                     SAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKLVKATNYPKCLLCMENEGYQ
                     GRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIFLNSQHVPMAITSKTFEQLL
                     EIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPMEKAKFESEFRFKDFEDVNA
                     GIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEVDIIAMTEDVPHHTVTPIAR
                     KVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKENIGLIEVMGLAILPPRLKPE
                     LEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVNSVVQHEAGQVFARVLEDAG
                     VYKNTPSGHEAFMRFVKSVGIN"
     gene            1432..2412
                     /gene="galE"
                     /locus_tag="ACSUUC_001870"
     CDS             1432..2412
                     /gene="galE"
                     /locus_tag="ACSUUC_001870"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HHQ8055023.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWN"
     gene            2622..3281
                     /locus_tag="ACSUUC_001871"
     CDS             2622..3281
                     /locus_tag="ACSUUC_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HHQ8055024.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3306..4373
                     /locus_tag="ACSUUC_001872"
     CDS             3306..4373
                     /locus_tag="ACSUUC_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HHQ8055025.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4476..5486
                     /locus_tag="ACSUUC_001873"
     CDS             4476..5486
                     /locus_tag="ACSUUC_001873"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8055026.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5498..7189
                     /locus_tag="ACSUUC_001874"
     CDS             5498..7189
                     /locus_tag="ACSUUC_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8055027.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEHFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7192..7902
                     /locus_tag="ACSUUC_001875"
     CDS             7192..7902
                     /locus_tag="ACSUUC_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HHQ8055028.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2676 a         1127 c         1568 g         2576 t
ORIGIN      
        1 gaaattgaca aaatatatgt gaaaaataga gtactagcgt taataggtga ggagggaact
       61 gatcgcattt ccgatgaaaa tgacctgaaa caaataaaag attacttagt ggaaatcgcc
      121 ttaaaaaacg gtaaaattaa agatttaatc gaggaaaagg aatgtttagg agcagagtta
      181 atgaatttca tagttccttt acctagtcga ttaaatgata ttttttggag ttcatatgat
      241 atatcacctc aagaagcagt tgaagagttt tataagttaa gtaaagatag tgattatatt
      301 aaaacttctg ctattgctaa gaatattgag tttcgagcat caactaaata cggagagcta
      361 gagattacga taaatttgtc aaaacccgaa aaagatccaa aaacaattgc tgctgaaaaa
      421 ttagtaaaag ccactaatta tcccaaatgt ttactatgta tggaaaatga aggatatcag
      481 gggcgaataa attatccagc acgttcgaat catagaatta ttcgattgaa acttggtgac
      541 gaagtatggg gattccaata ttctccctac ttatacttta atgagcatgc gatattttta
      601 aatagtcaac atgtaccaat ggctattacc tctaaaacat ttgaacaatt attggagatt
      661 gttgatattt tgccaggata ttttgctggt tcaaattctg atcttcctat ctcaggaggc
      721 tccattctta gtcataacca ctaccaggga gggaaacata ttttcccaat ggaaaaagca
      781 aaatttgaga gtgaatttcg ttttaaagac tttgaggatg ttaatgctgg tattgtaaaa
      841 tggccaatgt cagtaattag gttacaaagt gaaaataaaa atcgcttgtt agatttagct
      901 actaaaattc taaataagtg gagagaatat tcagatttag aagtagacat cattgctatg
      961 actgaagatg tcccacacca tacggtgact cctattgctc gtaaagtgga cgggagatat
     1021 gaattagata ttgttctaag agataatcat actactgaac agtacccaga tggtgttttc
     1081 catcctcatc aagatgtaca acatattaaa aaggaaaata tcgggttaat cgaagtgatg
     1141 ggacttgcga tattaccacc tcgtttgaaa ccagagttag aagaagttgg aaaatatctt
     1201 ttaggagagg ataacgcaat tgcggattat catttagaat gggccgacca attgaaagaa
     1261 aaatatcctc gcattaataa agaagaggtt aatagcgtag ttcaacacga agcaggacaa
     1321 gtgtttgcga gagttctgga agatgcagga gtttataaga atacaccgtc tgggcatgaa
     1381 gcgtttatga gatttgttaa gtcggttgga attaattagg aggaaacaaa aatggcaata
     1441 ttggtaacag gcggagctgg ttatattggt agccataccg tagtagaatt actaaattta
     1501 ggaaaggaag tcatcattgt cgacaacctt tcgaactcta gcatcttggt gctagaccgt
     1561 attgaagcaa ttacaggaat acgtcccgtg ttttacgaat tagatgtttg tgataaacca
     1621 gcattgagaa aggtatttga acaagaatcg attgatgctg caattcattt tgcaggttat
     1681 aaagctgtcg gagaatccgt gcaaaagcct gtgatgtact acaaaaataa tattatgagt
     1741 acattggcac ttgttgaagt gatgtcagaa tttaatgtta aaaagattgt cttttcttca
     1801 agtgcgactg tatatggaat taacaatcag tcacctctaa ttgagactat gcaaacaagt
     1861 gcgacaaatc cttatgggta tacgaaagtg atgcttgagc aaattttaaa agatgttcat
     1921 gtggcagatt cagaatggag tattgcgttg cttcgttatt tcaatccaat tggtgctcat
     1981 gagtctggtt tgattgggga agatccctca ggaattccta acaacttgat gccctatatt
     2041 gcacaagtag cggtaggtaa gctgtcagaa ctaagtgtgt tcggaaatga ttatgatacg
     2101 cttgacggta ctggtgtgcg cgattatatc catgtagtag atttagcaat aggacatata
     2161 aaagctttag aaaaagtatc tgaaaaaaca gatgtttata tctataacct aggctcggga
     2221 gaaggcacta gtgtattaca acttgtaaat acatttgaaa gtgttaataa gatccctatt
     2281 ccttataaaa tagttccaag acgttcagga gacgttgcaa cttgttatgc aaatgcagac
     2341 aaagcatata aggaattaaa ttggaggaca acaaaatcga ttgaagacat gtgtagagat
     2401 acatggaatt agcaatcaaa aaatcccaat ggctataatt gatgatactg tctatatgag
     2461 tgctgtattt tggaaaaatt acttaacctt ttaatgaaat gcatatttaa tgaaagataa
     2521 attaaaaaaa atgtttgaca gcgcttgaca aaggaaacgg tttcattgta taatgtaaac
     2581 atagtgacac cgatgtcaaa tataaaaaag aaggtcttta tatgaaaaac ttaacaaaaa
     2641 ttaagttcaa agagaatggg gaatttaatc atttccctgg gaatacagtt gtagcaaatc
     2701 tttatactaa acaagatttg atggaagttg ttgatattat tcaatcacgt tatagagaat
     2761 taccatttat cgataagttt actttaactc caaggaattc tattcacatg actgtaattg
     2821 aattgttgtg ccatgaaaat cgtgaaacgg agttttggag cagtaatctt cctctagata
     2881 cacctttaca ggaaatacat gattactttg ctaaacaact tgaaattttt ccattgttgg
     2941 atgaagaaat tcatatgcgt ataactgaaa tgggaaaaca aaacatacta gttgaacctg
     3001 cagatgaagc ttctgcaaag agattagaag aaattcgtac ttatgtctca gaaaaagcag
     3061 gtgtttgttt ccctaatcat gatagatatc aattccatat ttcaattggg tatcttcgga
     3121 ttcctctaac cgaagaggag gaagaagagt ttactaaagt cagagcagaa ttaactgaaa
     3181 ttttattaga gaagattcca actattactg taaaccgtat tgactatact gtatttgaag
     3241 atatgagaca atttgttcca tatcacgaaa aatttaaata aaataataaa aaaggagaac
     3301 ttatcatgaa aaaaatgaaa gtttggtcta ctgtacttgc aacgggagtt gctcttacta
     3361 cacttgctgc ttgctctgga ggttcaaatt ctacgactgc ttcttcatct gaagaaaaag
     3421 ctgataaaag tcaagaatta gtaatctatt cgaactcagt ctcaaatggt cgtggtgatt
     3481 ggttaactgc taaagcaaaa gaagctggtt ttaatataaa aatggttgat attgctggcg
     3541 ctcaattagc agaccgtgtt attgctgaga agaataatgc agttgcagat atggtatttg
     3601 gaattggtgc tgttgactca aataaaatta gagatcaaaa attactagta cagtacaagc
     3661 ctaaatggtt agataaaatt gatcaatctt tatcagataa agataattat tataatcctg
     3721 tgattgttca accattagtt ttaattgggg cgcctgatgt aaaagaaatg cctaaagatt
     3781 ggactgaatt aggtagtaag tataaaggta aatattcaat ttatggtctt caaggtggta
     3841 caggacgggc aattctagca agtatcttag ttcgttacct tgatgaaaaa ggagatttag
     3901 gcgtatcaga aaaaggatgg gaagttgcaa aagaatactt tgcaaatgcc tatactcttc
     3961 aaaaaggtga aagctcagtt gttaaagcgt tagataaaga aagcccaatt caatacggta
     4021 tgatctgggg ttctggagcg ttaatcggac aaaaagaaca aaatgttgaa ttcaaagtta
     4081 tgactcctga gattggtgta ccatttgtaa ctgaacaaac tatggtttta agcactagta
     4141 aaaaacaagc gttagctaaa gaatttattg attggtttgg tcaatcagaa attcaagtag
     4201 aatatagtaa aaaatttgga tctattcctg caaataaaga tgccctaaaa gagttacctg
     4261 aagatacgaa aaaatttgtt gatcaagtga aaccacaaaa tattgactgg gaagctgttg
     4321 gaaagcattt ggatgaatgg gtagaaaaag ctgaattaga atacgtaaaa taagaaataa
     4381 gagttatttt ttatgtccaa gtctctctat tatttctaaa tttaaggaag aaataaagag
     4441 aggcttttgg tttagtaata gagggagtta gtgagatgat taaatttgat aatattcaaa
     4501 ttaaatatgg tgattttgtt gcaattgata atctgaattt agatatacat gaaggggaat
     4561 tctttacatt tcttgggcct tcaggatgtg gtaaatcaac tactttgaga gcattggtag
     4621 gttttttaga tccatcatca ggaagtattg aagttaatgg aacagatgtc actcatttgg
     4681 aacctgaaaa gcgtggaatt ggtattgtat ttcaatctta tgcgctattt ccaactatga
     4741 ctgtttttga taatattgca tttggtttaa aagttaagaa ggtagctcca gatgttatta
     4801 aagctaaagt atcagcagtg gcagcaaaaa ttaagatctc tgatcaacag ttacagcgta
     4861 atgtatcaga attatctggg ggtcaacaac aaagggtagc attggctcgt gctctggttc
     4921 ttgaacctaa aattctttgt ctagatgaac cattgtcaaa ccttgacgca aaattacgtg
     4981 tagatttgag aaaagagttg aaaagacttc aaaaagagtt aggtattact actttatatg
     5041 ttactcatga tcaagaggaa gccttgactt tatctgatag aattgcagtc tttaacaatg
     5101 gatacatcga acaggtcggt acaccagtag agatttatca taattctcaa actgaatttg
     5161 tatgtgattt tattggagat attaatgttt tgaccgatga aacagtccac gaagtattac
     5221 tgaaaaatac aagcgttttc ttagaagata aaaaaggata cattcgatta gagaaagttc
     5281 gattcaatcg tgaaactgaa caagatttca ttctaaaagg gacaattatt gatgttgagt
     5341 tttctggagt tacaattcac tatacaataa aagtttctga aagtcagatt cttaatgtaa
     5401 caagtattga tagtcaggct gctattagat ctgtcggaga aagtgtggaa ttatttatca
     5461 caccatcaga cgttctgcaa ttttaaggag gtgcagtatg cgtcataaat taaatttaaa
     5521 agattggctt attcgtttag ggttaatctg gttcttagta acatttatta tttatccaaa
     5581 ctttgatcta gtagtgaatg tatttgtaaa aggaggagaa ttttcccttg atgctgtaca
     5641 tcgtgttcta aaatctcaga gggcacttca gagtattatg aacagtttta agttagcatt
     5701 ttcactcatt attacagtta atgtcgtagg tattctttgt gttctattta cagagcactt
     5761 tgatattaaa ggtgctaaaa ttttaaaatt aggttatatg acctctttaa tttatggagg
     5821 agtggtttta gcgactggat ataaatttgt ctatggtcca tatggattga ttacaaaatt
     5881 tttacaaaat gttatccctt ctttagaccc taactggttt attgggtatg gtgcagtctt
     5941 attcattatg acattttcag gaactgctaa tcatacattg tttttaacaa atacaattcg
     6001 aagcgttgac tatcacacta ttgaggctgc tcgaaatatg ggagcaaaac catttactgt
     6061 tttccgaaaa gtagtgttac caaccttaat tccaactcta tttgcactta ctattatggt
     6121 ttttcttagt ggtttatctg cagtagcagc acccatgatt gttggtggta aagaatttca
     6181 aactataaat ccaatgatta ttacatttgc agggatgggg aattctcgtg atttagctgc
     6241 cttacttgca attattttag gtattgcaac tacaattttg cttactatca tgaataagat
     6301 agaaaaaggt ggaaattata tttctatctc taagactaaa gcgcctctta aaaaacaaaa
     6361 aattgcgtct aagccttgga atatcattgc tcacattgta gcatatggat tgttcacagt
     6421 tttcatgctt ccactaattt ttatagtatt atactcattt acagatccag ttgcaattca
     6481 aacaggtaac ttaacattat caaactttac tttagaaaat tatcgcttat tctttagtaa
     6541 tagtgcggca ttctctccat tcttggtcag ctttatttat tctattattg ctgcgacaac
     6601 agcaacaatt ctcgcagttg tatttgctcg tgttgtcaga aaacataaat ctcgttttga
     6661 tttcttattt gaatatggtg ctctacttcc ttggttatta ccaagtacgc ttttagcagt
     6721 aagtttatta tttactttta atcagccaca atttcttgtc ttgaatcaga ttttggtagg
     6781 tagtttggta attctactta ttgcatatat agttgtaaaa atcccatttt cttatagaat
     6841 ggtacgtgct attttattta gtgttgatga tgagatggaa gatgcagcaa gaagtatggg
     6901 tgcttcacct ttttatacta tgatgaaggt tatcattcca tttattttac cggttgttct
     6961 ctctgttatt gctttaaact ttaactcttt attaactgac ttcgacttat ctgtattcct
     7021 ttaccatccc ctagctcaac cattaggtat tacgattcga tctgcaggtg atgaaacagc
     7081 aacatctaat gcacaagctc tggtatttgt ttatacaatt gttctgatga ttatttctgg
     7141 aacggtatta tacttcacac aaagaccggg gcgtaaagta aggaaataat catgacagcc
     7201 actagtcttg ggttatcaaa tattgaaata gttgtcagga ttgttttatc agtagtcatt
     7261 ggtagtataa ttggtttaga gagagggagc aaatcccagc ctgcaggcat ccgaacttat
     7321 agtattgttt gtctagctgc atgtttgatt atgatgacga atgaatacgt atcttataaa
     7381 tttgggacag gagatcctac acgattagga gctcaagtta tatcaggtgt gggttttcta
     7441 ggcgctggaa cgattcttat tacagataaa aagaaaatta caggtctgac aactgcagca
     7501 ggcatttggg cttcggcagg aattggatta gctattggag taggttttta tgagggagct
     7561 cttttagtag ccatttctgt ttggggtgtg atatccatgt tccaaccact aaaaaaatat
     7621 ctacaaaatc gttctaaaat gattgaattg tatatagtgg ttaaatctac agaagcctat
     7681 aatcgtgtat tggtttattg tgcagaaaat ggtatcagaa tgaccgattc aagaacagcg
     7741 tttggagatg ttaattctga cagaattgaa tactttgatg ttccagataa aaaaatagcg
     7801 tcatttatta ctctggaatt atcaggtaga tttgaacatc ttcgactgat ggaagaaatt
     7861 gctaatattg taggtgttat ttatgtcgaa gaaattagct gaaatttagt aaacaaaggg
     7921 acagatgttt ttgtcctttt gtttttt
//
LOCUS       DBJKQU010000065         7586 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.065, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000065 DBJKQU010000000
VERSION     DBJKQU010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.065"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            580..1032
                     /locus_tag="ACSUUC_001876"
     CDS             580..1032
                     /locus_tag="ACSUUC_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HHQ8055029.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1051..2388
                     /locus_tag="ACSUUC_001877"
     CDS             1051..2388
                     /locus_tag="ACSUUC_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHQ8055030.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2467..3351
                     /locus_tag="ACSUUC_001878"
     CDS             2467..3351
                     /locus_tag="ACSUUC_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHQ8055031.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3351..4184
                     /locus_tag="ACSUUC_001879"
     CDS             3351..4184
                     /locus_tag="ACSUUC_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHQ8055032.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4202..6295
                     /gene="nanB"
                     /locus_tag="ACSUUC_001880"
     CDS             4202..6295
                     /gene="nanB"
                     /locus_tag="ACSUUC_001880"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HHQ8055033.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPALIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGDSQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSSSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6307..7410
                     /locus_tag="ACSUUC_001881"
     CDS             6307..7410
                     /locus_tag="ACSUUC_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HHQ8055034.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
BASE COUNT         2536 a         1151 c         1542 g         2357 t
ORIGIN      
        1 atactctaat tgaaaacggt aacaaaacta atttagagaa tgaaatatag agtatttctc
       61 tcttaaaagt ttttggtgaa acgagatgta gaaaggagat ttagccaaag agtctattag
      121 tgctagaata atagattaga attattttag aaaaacgaag tgagcagctt ataaattcaa
      181 gtccccaaat agattcatac tagtatcttt tgcaaaaaat aaagggcgac ttccttcatg
      241 aatatcaatt tcatctataa ggaaggtagc taattgaact aacttattta ttctgtttgt
      301 cgctagaaaa atcagacctc cttgtgaaga ttgaggagat acttaatgaa aatcaaagaa
      361 gaaactagca agctagtagc agattgccca aaacaccgct ttgaggttgt agataagact
      421 gacctatata atccaaggtg aagcgactgt ggtttgaaga gattttcaaa gagtataggc
      481 tagagagtag tgtttttatg tccttctagt agaaaatgct agacagaaga atggggaact
      541 tggataggaa aaatagattg agaaaggagg ttagaagaga tgattattac aaaaattagc
      601 cgtttaggaa cttatgtggg agtaaatcca cattttgcaa cattaataga ttttctagaa
      661 aaaacaggac tagaaaattt aacagaaggt tcgattgcta tcgatggtaa tcgattgttt
      721 gggaattgct ttacttatct agcagatggt caagcagggg ctttctttga aacccaccaa
      781 aaatatttgg atattcattt agttttggaa aacgaagaag ccatggctgt tacatcgccg
      841 gaaaatgtaa gcgttaccca agaatatgat gaagagaaag atattgaatt atacacaggg
      901 aaagtggaac agttggttca tttgagagct ggcgaatgcc tcatcacttt tccagaagat
      961 ttacatcaac ccaaggttcg tataaatgat gaacctgtga aaaaagttgt ctttaaagtt
     1021 gcgatttctt aatgtagaaa gagaagaacg atgaaaaaaa tgagaaagtt tttatgtcta
     1081 gctggaattg cgctagcggc tgttgccttg gtagcttgtt caggaaaaaa agaagctaca
     1141 actagtactg aaccaccaac agaattatct ggtgagatta caatgtggca ctcctttact
     1201 caaggacccc gtttagaaag tattcaaaaa tcagcagatg ctttcatgca aaagcatcca
     1261 aaaacgaaaa tcaagattga aacattttct tggaatgact tctatactaa atggactaca
     1321 ggtttagcaa atggaaatgt gccagatatc agtacagctc ttcctaacca agtaatggaa
     1381 atggtcaact cagatgcttt ggttccgcta aatgattcta tcaagcgtat tggacaagat
     1441 aaatttaacg aaactgcctt aaatgaagca aaaatcggag atgattacta ctctgttcct
     1501 ctttattcac atgcacaagt catgtgggtt agaacagatt tgttaaaaga acataatatt
     1561 gaggttccta aaacttggga tcaactctat gaagcttcta aaaaattgaa agaagctgga
     1621 gtttatggct tgtctgttcc gtttggaaca aatgacttaa tggcaacacg tttcttgaac
     1681 ttctacgtac gtagtggtgg aggaagcctc ttaacaaaag atcttaaagc agacttgaca
     1741 agccaacttg ctcaagatgg tattaaatac tgggttaaat tgtataaaga aatctcacct
     1801 caagattctt tgaactttaa tgtccttcaa caagctacct tgttctatca aggaaaaaca
     1861 gcatttgact ttaactctgg cttccatatc ggaggaatta atgccaacag tcctcaattg
     1921 attgattcga ttgatgctta tcctattcca aaaatcaaag agtctgataa agaccaagga
     1981 attgaaacct caaacattcc aatggttgtt tggaaaaatt caaaacatcc agaagttgct
     2041 aaagcattct tagaagcact ttataatgaa gaagactacg ttaaattcct tgattcaact
     2101 ccagtaggta tgttgccaac tattaagggg attagcgatt ctgcagccta taaagaaaat
     2161 gaaactcgta agaaatttaa acatgctgaa gaagtaatta ctgaagctgt taaaaaaggt
     2221 actgctattg gttatgaaaa tgggccaagt gtacaagctg gtatgttgac taaccaacac
     2281 attattgaac aaatgttcca agatatcatt acaaatggaa cagatcctat gaaagcagca
     2341 aaagaagcag aaaaacaatt aaatgattta tttgaggctg ttcagtagat gtaaaagact
     2401 agaaaatagg tgggatagtg agctgaaaag ctctagccca atcttgtaaa agaagggaga
     2461 aggagaatgg ttaaagaacg taatttaact cgctggatat ttgttttgcc agctatgatt
     2521 atcgtaggat tactctttgt ttatccgttt ttctcgagta ttttttatag ctttaccaat
     2581 aagcatttga ttatgcctaa ttataaattt gttggtttgg ctaactataa agctgtgcta
     2641 tcagatccca acttctttaa tgcgttcttt aattcaatta agtggaccgt tttctcatta
     2701 gttggtcaag ttttagtagg gtttgtattg gctttagctc ttcacagagt acgccacttc
     2761 aagaaattat ataggacatt attgattgtt ccttgggcat ttcctaccat cgttattgcc
     2821 ttctcttggc agtggattct aaacggggtt tatggctact tacctaatct aatcgtaaaa
     2881 ttaggtttaa tggaacatac acctgcattt ttgacagata gtacatgggc attcctatgt
     2941 ttggtgttta tcaacatttg gtttggagca ccaatgatta tggttaatgt gctttcagct
     3001 ttgcaaacag taccagaaga acaatttgag gctgctaaga tagatggtgc ttcaagttgg
     3061 caggtgttca agtttatcgt ctttccacat attaaagtgg ttgtaggact tctagttgtt
     3121 ttgagaactg tatggatctt taataacttt gacattatct acctcattac tggtggtgga
     3181 ccagccaatg ctacaacgac gcttccaatt tttgcttaca acctgggctg gggaactaaa
     3241 ttgttgggtc gtgcttcagc agttacagta ttgctcttta tcttcttggt ggcgatttgc
     3301 tttatctact ttgctatcat cagtaagtgg gaaaaggagg gtagaaaata atgaagaaga
     3361 aatccagtat ttatttagat attctctcac atgtactttt agttggtgcg accatcgttg
     3421 caattttccc attggtatgg attatcatat cttctgtcaa agggaaaggg gaattaactc
     3481 agtatccaac acgattttgg cctgaacagt ttacattaga ttatttcact catgttatca
     3541 acgatttgca cttcattgat aacattcgaa acagtttaat cattgccttg gctacaaccc
     3601 ttattgcgat tattatttct gctatggcag cctatggtat tgttcgattc tttcctaaat
     3661 tgggagcaat catgtcgaga ctactcgtca ttacctacat tttcccacca attttgttag
     3721 caattcccta ttcaattgcc attgctaaag ttgggttaac aaatagttta tttggcttga
     3781 tgatggttta tctatctttt agtgttccat atgcagtttg gctcttagtt ggatttttcc
     3841 aaacagttcc aattggaatt gaagaagcgg ctagaattga tggtgcaaat aaatttgtta
     3901 cgttttataa agttgtgcta ccgattgtag caccaggtat tgtagcaaca gctatttata
     3961 catttatcaa tgcttggaat gaattcctgt atgccttgat tttgattaac aatacaggaa
     4021 agatgacagt agcagtagcc cttcgttcac ttaatggttc agaaatacta gactggggag
     4081 atatgatggc agcgtctgtt attgtagttc ttccatcaat tattttcttc tctatcatcc
     4141 aaaataagat tgcaagtgga ttatcagaag gatctgtgaa gtagacgaaa gaaggaaaaa
     4201 aatgaataaa agaggtcttt attcaaaact aggaatttct gttgtaggca ttagtctttt
     4261 aatgggagtc cccgctttga ttcatgcgaa tgaattaaac tatggtcaac tgtccatatc
     4321 tcctattttt caaggaggtt catatcaact gaacaataag agtatagata tcagcccttt
     4381 gttattagat aaattgtctg gagatagtca gacagtagta atgaaattta aagcagataa
     4441 accaaactct cttcaagctt tgtttggcct atctaatagt aaagcaggct ttaaaaataa
     4501 ttacttttca attttcatga gagattctgg tgagataggt gtagaaataa gagacgccca
     4561 aaagggaata aattatttat tttctagacc agcttcatta tggggaaagc ataaaggaca
     4621 ggcagttgaa aatacactag tatttgtatc tgattctaaa gataaaacat acacaatgta
     4681 tgttaatgga atagaagtgt tctctgaaac agttgataca tttttgccaa tttcaaatat
     4741 aaatggtata gataaggcaa cactaggagc tgttaatcgt gaaggtaagg aacattacct
     4801 cgcaaaagga agtattgatg aaatcagtct atttaacaaa gcaattagtg atcaggaagt
     4861 ttcaaatatt cccttgtcaa atccatttca gttaattttc caatcaggag attctactca
     4921 agctaactat tttagaatac cgacactata tacattaagt agtggaagag ttctatcaag
     4981 tattgatgca cgttatggtg ggactcatga ttctaaaagt aagattaata ttgccacttc
     5041 ttatagtgat gataatggga aaacgtggag tgagccaatt tttgctatga agtttaatga
     5101 ctatgaggag cagttagttt actggccacg agataataaa ttaaagaata gtcaaattag
     5161 tggaagtgct tcattcatag attcatccat tgttgaagat aaaaaatctg ggaaaacgat
     5221 attactagct gatgttatgc ctgcgggtat tggaaataat aatgcaaata aagccgactc
     5281 aggttttaaa gaaataaatg gtcattatta tttaaaacta aagaagaatg gagataacga
     5341 tttccgttat acagttagag aaaatggtgt cgtttatgat gaaacaacta ataaacctac
     5401 aaattatact ataaatgata agtatgaagt tttggaggga ggaaagtctt taacagtcga
     5461 acaatattcg gttgattttg atagtagctc tttaagagaa aggcataatg gaaaacaggt
     5521 tcctatgaat gttttctaca aagattcgtt atttaaagtg actcctacta attatatagc
     5581 aatgacaact agtcagaata gaggagagag ttgggaacaa tttaagttgt tgcctccgtt
     5641 cttaggagaa aaacataatg gaacttactt gtgtcctgga caaggtttag cattaaaatc
     5701 aagtaacaga ttgatttttg caacatatac tagtggagaa ctaacctatc tcatttctga
     5761 tgatagtggt caaacatgga agaaatcctc agcttcaatt ccgtttaaaa atgcaacagc
     5821 agaagcacaa atggttgaac tgagagatgg tgtgattaga acattcttta gaaccactac
     5881 aggtaagata gcttatatga ctagtagaga ttctggagaa acatggtcgg aagtttcgta
     5941 tattgatgga attcaacaaa cttcatatgg cacacaagta tctgcaatta aatactctca
     6001 attaattgat ggaaaagaag cagtcatttt gagtacacca aattctagaa gtggccgtaa
     6061 gggaggtcaa ttagttgtcg gtttagtcaa taaagaagat gatagtattg attggaaata
     6121 ccactatgat attgatttgc cttcgtatgg ttatgcctat tctgcgatta cagaattgcc
     6181 aaatcatcac ataggtgtac tgtttgaaaa atatgattcg tggtcgagaa atgaattgca
     6241 tttaagcaat gtagttcagt atatagattt ggaaattaat gatttaacaa aataaaggag
     6301 aaaaacatgg ttaaatacgg tgttgttgga gcagggtatt ttggagctga attggctcgc
     6361 tatatgcaaa agaatgatgg agcagagatt actcttctct atgatccaga taatgcagag
     6421 gcgattgcag aagaattggg agcaaaagta gcaagttcct tagatgagtt ggtttctagc
     6481 gatgaagtag attgtgttat cgtcgcaact ccaaataatc ttcataagga accggttatt
     6541 aaggctgcac agcatggtaa aaatgttttc tgtgaaaaac caattgcgct ttcttatcaa
     6601 gattgtcgcg agatggtaga tgcgtgtaaa gaaaacaatg taacctttat ggcaggacat
     6661 attatgaatt tctttaatgg tgttcatcat gcaaaagaac tcattaatca aggagttatc
     6721 ggagacgttc tatattgtca tacagctcgt aatggttggg aagaacaaca accgtcagta
     6781 tcatggaaaa aaattcgtga aaaatcaggt ggtcacttgt atcaccacat ccatgaattg
     6841 gattgcgttc aattccttat ggggggcatg cctgaaactg taaccatgac aggtggaaat
     6901 gtggcccatg aaggtgaaca tttcggtgat gaagatgata tgatttttgt caatatggaa
     6961 ttttctaata agcgttttgc cttgttagaa tggggttcag cttatcgttg gggtgaacat
     7021 tatgtcttaa tccaaggaag caaaggtgcc atccgcttag acttattcaa ctgtaaagga
     7081 actcttaagc tagatgggca agaaagctat ttcttgattc acgaatcgca agaagaagat
     7141 gatgatcgga ctcgtatcta tcatagtaca gagatggatg gagcaattgc ttatggtaaa
     7201 ccaggtaaac gtactccatt atggctatca tctgtcattg ataaagaaat gcgctatctg
     7261 catgagatta tggaaggagc tccagtatca gaagaatttg caaaactttt gacaggtgaa
     7321 gctgccctag aagcaattgc tactgcagat gcttgtaccc agtctatgtt tgaagatcgc
     7381 aaagtaaaat tgtcagaaat tgtaaaataa attttggtat tctcctattt ataggtcgac
     7441 ttgctcctct gaaagtactt ttagaggagc tgtttgactt tgctagtttt tgaaactgaa
     7501 atctattata ctacaaacta ttgaaagcgt tttaatttta aggtataata atctcataga
     7561 aataaagaaa aggaggaaag aggatg
//
LOCUS       DBJKQU010000066         7466 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.066, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000066 DBJKQU010000000
VERSION     DBJKQU010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.066"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            129..284
                     /locus_tag="ACSUUC_001882"
                     /pseudo
     CDS             129..284
                     /locus_tag="ACSUUC_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol/lipid kinase family protein"
     gene            484..3759
                     /gene="rexB"
                     /locus_tag="ACSUUC_001883"
     CDS             484..3759
                     /gene="rexB"
                     /locus_tag="ACSUUC_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HHQ8055035.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3756..7406
                     /gene="addA"
                     /locus_tag="ACSUUC_001884"
     CDS             3756..7406
                     /gene="addA"
                     /locus_tag="ACSUUC_001884"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HHQ8055036.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDINHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRNRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKAHENLYEKLVNAQKKAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEIFANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2277 a         1569 c         1585 g         2035 t
ORIGIN      
        1 actatattag attgaaataa gatacgaaca gcttgattag ggaaatcaaa ttaatttcta
       61 gaaatatttt agcatccacg atgtactatt atagtttcaa tttactatag ttcaatcatt
      121 ctatcaagaa tattgaatat ataaaggcac gtaatattaa aacttcttct gatatcgaat
      181 tagagtccga tgttgatggc gataaatcag acaatctacc cgtcgacatt aagatactgg
      241 gacaacacat tgaagtgtat tccgtaccta agaaacaatc ataaaactca aagtcttgtt
      301 accgaggctt ttttattatg tgattttcag tagccagact tattctatct aatacaagta
      361 aagctaagta tttaagattt agcagatgat gaagaaaaga aaggatggcc taaatatttt
      421 aacagattta cgaggctaat catggtataa tatagggtga tgaaaaattc caacgaggct
      481 gagatgaaat tactttatac tgatattcga acttctttga cagaaattct aacaagagag
      541 gcagaagagc tagttgcagc tggcaagcgg gtcttctaca ttgcccccaa ctctctttct
      601 tttgaaaagg aacgcgccgt gctggaatgc ttgtcccagc aggcttcttt ttctattacc
      661 gtcacgcgct ttgctcaaat ggctcgttat ctggtcctga atgatttacc agttaaaact
      721 actcttgatg atatcggtct tgggttggcc ttttacaaat gccttgccga actcgatccc
      781 aaggacttgc gtgtttatgg cgctattaag caggatcctc aattgatcca gcagttaatt
      841 gagctttacc atgagatgac caaatctcag atgagttttt tggacttgga gaatttaaca
      901 gatgaggata agaggacgga tttactcttg atttttgaga aagtaacagc ctatcttaat
      961 caaggtcagt tagcccaggg aagtcagttg tcccatttga ttgaggctat tgagaatgac
     1021 aaggtaagta gtgattttaa tcaaatcacc ttggtcattg acggctttac tcgtttttct
     1081 gctgaggaag agcgggttgt ggacttactt cacggcaaag gtgttgagat tgttatcggg
     1141 gcttatgcta gtaagaaagc ctataccagt ccttttagcg agggcaatct ctaccaagcc
     1201 agcgtaaaat ttctccatca tctggcttct aaataccaaa cgcctgctca ggactgttct
     1261 caaactcatg agaagatgga tagttttgac aaggcctctc gtttgttgga gtcttcttat
     1321 gacttttcag aactcgcttt ggatgtcgat gagaaagacc gtgaaaattt acaaatctgg
     1381 tcttgtttga cgcaaaagga ggagttggag ctagtagccc gtagcattcg tcagaaatta
     1441 catgagaact cagacctgag ctacaagcat tttcgtattc tcttggggga tgtagcttct
     1501 taccagttat ctctcaaaac catttttgac cagtatcaga ttccttttta tcttggtaga
     1561 agcgaagcca tggctcatca tcccttgact cagtttgtcg agtctatttt agctttaaaa
     1621 cgttaccgtt ttcgtcagga ggatttgatt aatcttctta gaactgattt gtatactgac
     1681 ctcagtcagt ctgatattga tgcttttgag caatatatcc gctatcttgg tatcaatggc
     1741 ttgccagcct ttcagcaaat cttcaccaaa tcccaccatg gaaaatttaa tcttgagcgt
     1801 ttgaatgtcc tccgcctgag aattttagca cctcttgaaa ccctctttgc cagccgaaaa
     1861 caaaaggctg aaaacctcct acaaaaatgg agtgtctttc taaaagaagg agctgtgacc
     1921 aagcagttac aagatttgac aaccactttg gaagctgtag aacaggaaag acaagccgaa
     1981 gtttggaagg ctttctgcca tgttttagaa caatttgcga ctgtttttgc tggttcacag
     2041 gttagtctgg aagacttcct agccttgctc cattctggaa tgagtttgtc ccaataccgt
     2101 accattccag caacagtgga cactgttctg gtgcagagtt acgatttgat tgcaccattg
     2161 actgctgact ttgtctatgc tattggacta actcaggaca atttaccaaa aatttctcaa
     2221 aacaccagtc ttctgacaga tgaagaaagg caaaatctaa accaagcgac cgaagaaggc
     2281 gttcaattac tgattgccag cagtgaaaat ctcaagaaaa atcgctacac tatgctttcc
     2341 ttggtcaatt ctgctcgtaa gcagttgttc ttgtcggctc caagcctttt taacgaaagt
     2401 gaaagtaagg aatctgccta tcttcaagag ttgatccatt ttggatttag gcggagagag
     2461 aagaggatga atcacaaagg actgtctaag gaggatatgg ggtcctatca cagtcttttg
     2521 tctagtctgg ttgcctatca ccagcagggt gagatgagcg atactgagca agatttgact
     2581 tttgtcaagg ttctgtcgcg tgtcataggt aaaaaactag atctgcaagg tctggaaaat
     2641 ccagctatcc caaccagtcc aagcagcaag accttagcca aggacacctt gcaagctctc
     2701 tatcctgcca aacaggagtt ttacctgtct acgtcgggtt tgacagagtt ttatcgcaat
     2761 gaatacagtt atttcctacg ctacgtttta ggcttgcagg aggaattacg tttgcgtcct
     2821 gatgcccgta gtcacgggaa tttcttgcat cgtatctttg aacgcgcctt acagttgcct
     2881 aatgaagatt cctttgacca acgtctagaa caagctattc aagaaaccag tcaagaacgc
     2941 gaatttgaag ctatttatca agaaagtttg gaagcccagt ttaccaagga agttttgctt
     3001 gatgttgcac ggacgactgg acatattctc cgacacaatc cagccatcga aaccatcaaa
     3061 gaagaagcaa attttggtgg aaaagaccaa gcctttattc aattagacaa tggacgcagt
     3121 gtctttgtac gaggcaaggt ggaccggatt gaccgtttga aagctaatgg agcgatagga
     3181 gtagtagact acaaatccag tctgactcag ttccagtttc ctcatttctt taatgggctc
     3241 aattctcagt taccaaccta tcttgctgcc ctaaaaagag aaggggagca gaactttttc
     3301 ggcgccatgt acttggaaat ggctgaacct gtccaatctc tgatggcggt aaaaagtctg
     3361 gcaggagcag tggtagaagc cagcaaatct atgaaatacc aagggctctt cttggaaaaa
     3421 gaaagcagtt atttaggcga attttataac aaaaacaagg ctaatcaact gacagatgag
     3481 gaatttcagc tcctactgga ctacaatgcc tatctttaca agaaagctgc tgagaagatt
     3541 ttagcaggcc ggttcgccat caatccttat actgaaaatg gcagaagcat tgccccatac
     3601 gtccagcaac atcaggctat tacaggcttt gaagccaatt accatctggg ccaagcccgt
     3661 ttcctagaaa agttggacct agctgatggc aagcgtctgg tcggagaaaa actcaagcaa
     3721 gcttggtttg aaaaaataag agaggagtta aatcgatgaa gcttattccc tttttaagtg
     3781 aggaggagat tcaaaaactg caagaagcag aagcaaattc gagcaaggaa cagaagaaaa
     3841 ctgccgaaca aatcgaagct atctacactt ctggtcagaa tatcctggtc tcagcatcgg
     3901 ctggttctgg aaagaccttt gtcatggtag agcgcattct ggaccaattg gcgcgtggtg
     3961 tcgaaatttc tcaactcttt atctcaacct ttaccgtcaa ggctgcaact gaacttaaag
     4021 aacgtttaga gaaaaaaatc agcaagaaaa tccaagaaac agatgatgtc gatctcaaac
     4081 aacacttggg tcgccagttg gcagacctac ccaacgctgc catcggaacc atggactctt
     4141 tcacacaaaa attccttggc aaacatggtt atctgcttga tattgcacct aatttccgta
     4201 ttttacaaaa ccaaagcgag caacttcttc tcgaaaacga agtctttcat gaggtctttg
     4261 aagcgcatta ccaaggtaaa cagaaagaga gctttagtca tttgctgaaa aactttgctg
     4321 ggcgtggcaa ggacgaacgg ggtctgcggc agcaagtcta taaaatctat gacttcctcc
     4381 aatccaccag taatcctcaa aagtggctga gtgaatcttt cctcaaaggc tttgagaaag
     4441 ctgattttac cagtgaaaaa gaaaaactga ctgagcaaat caaacaagcc ctctgggatt
     4501 tggaaagctt tttccgttac catctggata acgatgccaa ggagtttgca aaggctgcct
     4561 atttagaaaa tgttcagtta attctggatg aaattggctc cctaaatcag gagttcgata
     4621 gtcaggctta tcaggcagta cttgcgcgtg ttgtcgccat ctctaaggag aaaaacggtc
     4681 gagctctgac taatgccagc cgtaaggctg atttgaagcc cctggctgat gcctacaacg
     4741 aagagagaaa gacccagttt actaaactag gacaattatc agaccagata gcgattctcg
     4801 actatcaaga acgttatcat ggagacactt ggaaactagc taaaaccttc caatctttca
     4861 tgagcgattt tgtagaggct tatcgtcaga gaaaacgaca ggaaaatgcc tttgaattcg
     4921 ctgatatcag ccattacacc attgagattt tagaaaattt cccacaagtt cgtgagtctt
     4981 atcaggagcg cttccatgaa gtcatggtcg atgagtatca ggatatcaac catattcaag
     5041 aacggatgct ggaattgttg tctaatggcc acaatcgctt tatggtggga gatatcaagc
     5101 aatccatcta tcgtttccgt caggcagacc cgcagatttt caatgagaaa ttccaacgct
     5161 atgcgcaaaa tcctcaagaa ggcaagctca ttctcctcaa ggaaaatttc cgtagtagtt
     5221 cagaagtgct gtcagcaacc aatgatgtct ttgaacgtct catggaccaa gaggtcggcg
     5281 aaatcaacta tgataacatg caccagcttg tttttgccaa taccaaactg actcccaatc
     5341 cagacaacaa ggccgaattt ctcctctacg acaaggacga tacaggtgag gaagaagaga
     5401 gtcaaacaga aacgaaacta acaggcgaaa tgcgcttagt tatcaaggag atccttaaac
     5461 ttcatcagga aaaaggtgtt gcctttaagg aaattgccct tctgacctct agtcgtaatc
     5521 gtaatgacca aattctactt gccctgtctg agtacgggat tcctgtcaaa actgacggag
     5581 agcaaaacaa ttatctccaa tccctagaag tgcaagtcat gctagacacc cttcgtgtca
     5641 ttcacaatcc cctgcaagac tacgccttgg ttgcccttat gaagtctcca atgtttggtt
     5701 ttgatgagga tgagctagca cgtttgtccc ttcagaaagc agaggataaa gcccacgaaa
     5761 atctctatga gaaactagtc aatgcacaaa aaaaggcaag tagtcaaaaa ggcttgattc
     5821 acacagctct agctgaaaaa ctaaagcaat tcatggatat cctagcttct tggcgcttgt
     5881 atgccaaacc ccactctctc tatgacttga tttggaagat ttacaacgac cgtttttatt
     5941 atgactatgt tggggctttg ccgaatggtc ctgctaggca ggccaatctc tatgccctag
     6001 cactgcgtgc tgatcaattt gaaaagagca atttcaaagg tttgtcgcgt tttattcgta
     6061 tgattgacca agtcttagaa gcccagcacg atttggcaag cgtggccgtc gcaccgccaa
     6121 aagatgcagt agagctcatg accatccaca agagtaaagg gctggagttt ccttacgtct
     6181 ttatcctcaa tatggatcaa gatttcaaca aacaagactc tatgtcagaa gtcattctca
     6241 gtcgtcagaa tggtcttggt gtcaaatata ttgccaagat ggagacaggg gcagtagaag
     6301 accactatcc taaaaccatc aaactctcca ttcctagtct gacctatagg cagaacgaag
     6361 aggaattaca gctagcaagc tattctgagc agatgcgttt gctgtatgtt gctatgacgc
     6421 gggctgagaa aaagctctat cttgtcggca agggttctcg tgaaaagctg gaatccaagg
     6481 aatacccagc agccaaaaat gggaaactaa atagcaatac tagactgcaa gcacggaatt
     6541 tccaagattg gctttgggct atcagtaaag tgtttactaa ggacaagctc aactttagtt
     6601 atcgttttat tggcgaagat cagttgacca gagaagctat cggagagttg gaaaccaaga
     6661 gtcctctcca agatagctcc caagcagaca atcgtcagtc agataccatc aaagaagctc
     6721 tggaaatgct gaaggaggtg gaagtttata atactcttca ccgcgcagct attgaacttc
     6781 ctagtgttca aaccccaagt caaatcaaga aattctacga accagttatg gatatggaag
     6841 gtgtcgagat tgctggtcaa ggtcagtcag taggcaagaa aatcagcttc gatttgccag
     6901 atttttcaac caaagaaaag gtaactggag ctgagattgg tagtgctact cacgaactca
     6961 tgcagagaat tgacctcagc cagcaactaa cccttgctag cctaacagaa acactcaaac
     7021 aagttcaaac tagccaagct gtcagagaca agatcaatct tgataaaatt cttgctttct
     7081 ttgacacagc actcggtcag gaaatttttg ctaataccga ccatctctat cgcgagcaac
     7141 ctttctccat gctcaaacga gaccaaaaga gtcaggaaga ctttgttgtc cgtggtatcc
     7201 ttgatggcta tctgctttac gaaaacaaaa ttgttttgtt cgactacaag acagaccgct
     7261 atgatgaacc aagtcaactc gtagaccgct atcgtggtca gttagctcta tacgaagagg
     7321 ctttatcacg agcctattcg attgaaaata ttgaaaaata cttgatttta ctcggtaaag
     7381 acgaggttca agttgtaaaa gtataactta tactcttcga aaatctcttc aaaccacgtc
     7441 agcttcgcct tgctgtatat atggtt
//
LOCUS       DBJKQU010000067         7330 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.067, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000067 DBJKQU010000000
VERSION     DBJKQU010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7330
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.067"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            226..6657
                     /locus_tag="ACSUUC_001885"
     CDS             226..6657
                     /locus_tag="ACSUUC_001885"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HHQ8055037.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPHEVVLADTSNSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDNNTSNEEARIKE
                     DSNQSQGDNAHSSANKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSSLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLTGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNEGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYINGKEYTSFDDIKQIIDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REEHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
BASE COUNT         2892 a          982 c         1399 g         2057 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggagt ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctca tgaggtagtc
      301 ttagcagaca catctaactc tgaagatgct ttaagcatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa cataaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca attattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacaataa cactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatctcaag gagataatgc acactcgtct gcaaataaaa acacagaaaa tcccaaaaaa
      601 gaagataaag ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccagtcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcta tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaaggt
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttagggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctgata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttacggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacactgatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataacgaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgacaaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagacc taaagaaact cattaaaaag
     4441 aaatataagg aagaagacga ctttgtaact ggtggaaaaa gaacagtaga acttgattat
     4501 aaatatgacg ataaaggaaa tataactgcc tatgaagatg aaagtgctct agaatatgaa
     4561 actgaaaaat ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaataact ataaatttat agaaatcaaa gcgactaagt atgactcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa aattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccctatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga cctttcaaaa aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagtga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatataaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa tagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagagcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagat
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa cagccattta taactcaatt atttagttta cttcactatt gatactattt
     6781 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     6841 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     6901 gatgagacaa tttcaaggaa ttaagtagcg tttggttgct taattccttt ttatttggaa
     6961 ggaagttttt cgtaaccgcc caataacgaa gtctattgga cggttacgat atgatcactg
     7021 acttcgtcag tcttatctac aacctcaaaa ctgtgttttg agcaacctgc ggctagcttc
     7081 ttagcttact ctttgatttt cattgagtat tagaacagaa aaaatgcttg gagtatttgt
     7141 ttgtgtgttt gtttttatat aacaaactat aaacaaaaca aaaatataaa aaaagagaca
     7201 aaaaagaaca gaaagtaatt gacaacggtt tcatatagtg ttatacttat ggcataaagt
     7261 taatggaaag aagggaaaac cttatggtat tagattattt ctttgacaaa aaccttgtgt
     7321 tttgcttaga
//
LOCUS       DBJKQU010000068         6542 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.068, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000068 DBJKQU010000000
VERSION     DBJKQU010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6542
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.068"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            237..1682
                     /gene="cps4A"
                     /locus_tag="ACSUUC_001886"
     CDS             237..1682
                     /gene="cps4A"
                     /locus_tag="ACSUUC_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HHQ8055038.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSLSVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLVAYKSLIAGETKAIVLNSVFENIIELEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTSRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVLLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EVLKNYSTIINSLQDSIQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYMMEIDDSSLAVVKAAIQDVMEGR"
     gene            1684..2415
                     /gene="cps4B"
                     /locus_tag="ACSUUC_001887"
     CDS             1684..2415
                     /gene="cps4B"
                     /locus_tag="ACSUUC_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HHQ8055039.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAESFLQVREIAKEVADDLVIAYGAEIYYTPDVLDKLGKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALGNNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQNLVHVIASDMHNLDGRPPHMAEAYDFVT
                     QKYGEAKAQELFIDNPRKIIMDQLI"
     gene            2424..3116
                     /locus_tag="ACSUUC_001888"
     CDS             2424..3116
                     /locus_tag="ACSUUC_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein"
                     /protein_id="HHQ8055040.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILLVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKSGLTNQDLQAGSYLVKDYREIILSQDALEKVATNLKLD
                     MPAKTLASKVQVTVPTDTRIVSISVKDKQPEEASRIANSLREVAVERIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELFDTRVKRPEDVEDVLQIP
                     LLGLVPDLDKMK"
     gene            3126..3815
                     /locus_tag="ACSUUC_001889"
     CDS             3126..3815
                     /locus_tag="ACSUUC_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HHQ8055041.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNSLCMNLQLSGDGLKVFSITSVK
                     LGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFTTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVNKYGSY
                     GNYGDYGKNKK"
     gene            3830..5197
                     /locus_tag="ACSUUC_001890"
     CDS             3830..5197
                     /locus_tag="ACSUUC_001890"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HHQ8055042.1"
                     /translation="MNGKVVNSSLAIIHSFLVILLTYLLSAVREAEIASATAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVIFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLVSVVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMCVDAEDKKRELMEQNTM
                     QGGMFKVDDDPRITKVGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            5184..5681
                     /gene="pssD"
                     /locus_tag="ACSUUC_001891"
     CDS             5184..5681
                     /gene="pssD"
                     /locus_tag="ACSUUC_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PssD/Cps14F family polysaccharide biosynthesis
                     glycosyltransferase"
                     /protein_id="HHQ8055043.1"
                     /translation="MERSKGMKNKKKVCFCASSGGHYEQLMKLEPIMRQQDSYLITEY
                     TDYNKGESEKKDINKVFYLLQINRLEFFWIVKLIWISLKSLYILLRIRPKVVICTGVL
                     AMIPFCLLSKMFGAKLIYIESFAKVTTPTLTGRILYRYADRFYVQWESMLDIYPNAVY
                     KGGLY"
     gene            5682..6161
                     /gene="pssE"
                     /locus_tag="ACSUUC_001892"
     CDS             5682..6161
                     /gene="pssE"
                     /locus_tag="ACSUUC_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PssE/Cps14G family polysaccharide biosynthesis
                     glycosyltransferase"
                     /protein_id="HHQ8055044.1"
                     /translation="MIFITVGTQKHPFNRLLKKIDQLIELEVIKEEVFAQIGASDYKP
                     KYFSYNSFLSSIDMNEKMREASMVITHGGTASIVKALKLRKKIIAVPRLEQFGEHVDN
                     HQLQIITVLGEEGYILPCFDIEQLGTVYQKAQTFTTKPYISNSYALLEDIRQYIDSL"
     gene            6174..>6542
                     /locus_tag="ACSUUC_001893"
     CDS             6174..>6542
                     /locus_tag="ACSUUC_001893"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055045.1"
                     /translation="MTKVLQIGPSINLSKGGMSAVIRDLTYSPLLSGDFDITAYQSFI
                     DGSLVTRLTYSSYALLKFVVHSGNYDIYHIHTATRGSCWRKLLYLKLLKSKNKKAILH
                     IHGAEFQIFYDSLPEYKKNKV"
BASE COUNT         2073 a         1043 c         1402 g         2024 t
ORIGIN      
        1 cattgtgtac tatagtagat tgaaactaga atagtacaca tctgcttcta aaacattgtt
       61 agaaatcgat ttgactgtcc cgatcgattt gtcatgttct tatttcattt tactatattt
      121 ttgttttgcg ggaagtctac taagatactt aaagatgcag atagtgaaaa aaaggtgtag
      181 acattaccgt aaaaaagtga tataatcgta agatgttcaa tgtataggtg ttaatcatga
      241 gtagacgttt taaaaaatca cgttcacaga aagtgaagcg aagtgttaat atagttttgt
      301 tgactattta tttattgtta gtttgttttt tattgttctt aatctttaag tacaatatcc
      361 ttgcttttag atatcttaat ctagtggtaa ctgcgttagt cctactagtt gccttggtag
      421 ggctactctt gattatctat aaaaaagctg aaaaatttac tatttttctg ttggtgttct
      481 ctatccttgt cagctcagtg tcgctctttg cagtacagca gtttgttgga ctgaccaatc
      541 gtttaaatgc gacttctaat tactcagaat attcgctcag tgtcgctgtt ttagcagata
      601 gtgagatcga aaatgttacg caactgacga gtgtgacagc accgactggg actgataatg
      661 aaaatattca aaaactacta gctgatatca agtcaagtca gaataccgat ttgacggtcg
      721 accagagttc gtcttacttg gttgcttaca agagtttgat tgcaggggag actaaggcca
      781 ttgtcctaaa tagtgtcttt gaaaatatca tcgagttaga gtatccagac tacgcatcga
      841 agataaagaa gatttatacc aagggattca ctaaaaaagt agaagctcct aagacgtcta
      901 agaatcagtc tttcaatatc tatgttagtg gaattgacac ctatggacct attagttcgg
      961 tgtcgcgatc agatgtcaat atcctgatga ctgtcaatcg tgataccaag aaaatcctct
     1021 tgaccacaac gtcacgtgat gcctatgtac caatcgcaga tggtggaaat aatcaaaaag
     1081 ataaattaac ccatgcgggc atttatggag ttgattcgtc cattcacacc ttagaaaacc
     1141 tctatggagt ggatatcaat tactatgtgc tattgaactt cacttctttc ttgaaaatga
     1201 ttgacttatt gggaggggta gatgttcata atgatcaaga gttttcagct ctacatggga
     1261 agttccattt cccagtaggg aatgtccatc tagactctga gcaggctcta ggttttgtac
     1321 gtgaacgcta ctcactagcc gatggagacc gtgaccgtgg tcgcaaccaa caaaaggtga
     1381 ttgtggctat ccttcaaaaa ttaacgtcaa ccgaagtact gaaaaattat agtacgatca
     1441 ttaatagctt gcaagattct atccaaacaa atatgccgat tgagactatg atagatttag
     1501 tgaatactca gttggaaagt ggaggtaatt ataaagtaaa ttctcaagat ttaaaaggga
     1561 caggtcggat ggatcttcct tcttatgcaa tgccagacag taacctctat atgatggaaa
     1621 tagatgatag tagtttagct gtagttaaag cagctataca ggatgtgatg gagggtagat
     1681 gaaatgatag acatccattc gcatatcgtt tttgatgtag atgacggtcc caagtcaaga
     1741 gaggaaagca aggctctctt ggcagaatcc tacaggcagg gggtgcgaac cattgtctct
     1801 acctctcacc gtcgcaaggg tatgtttgaa actccggaag agaagatagc agaaagcttt
     1861 cttcaggttc gggaaattgc aaaagaagta gcagatgatt tagtcattgc ttacggggct
     1921 gaaatttact acacaccaga tgttctggat aagctgggaa aaaagcggat tccgaccctc
     1981 aatgatagtc gttatgcctt gatagagttt agtatgaaca ctccttatcg cgatattcat
     2041 agcgccttga gcaagatctt gatgttggga attactccag tcattgccca cattgagcgc
     2101 tatgatgctc ttggaaataa tgaaaaacgc gttcgagaac tgattgatat gggctgttac
     2161 acgcaagtaa atagttcaca tgtcctcaaa ccaaaacttt ttggagaacg ttataaattc
     2221 atgaaaaaaa gagctcagta ttttttagag cagaatttgg ttcatgtcat tgcaagtgac
     2281 atgcacaatc tagacggcag acctcctcat atggcagaag catatgactt tgttacccaa
     2341 aaatacggag aagcgaaggc tcaggaactt tttatagaca atcctcgaaa aattataatg
     2401 gatcaactaa tttaggagaa atgatgaaag aacaaaacac gatagaaatc gatgtatttc
     2461 aattatttaa aaccttgtgg aaacgcaagc taatgatttt attagtggca cttgtgacag
     2521 gtgcgggggc ttttgcatat agcactttta ttgttaagcc agaatatacg agtaccacgc
     2581 gaatttacgt agtgaatcgc aatcaaggag acaagtcggg gctgacaaat caggatttgc
     2641 aggcaggatc ttatctggta aaagactacc gtgagattat cctttcgcag gatgcattgg
     2701 aaaaagtagc gacaaatttg aagttggaca tgccagcaaa aacgttagct agcaaagttc
     2761 aagtgactgt accaactgac actcgtatcg tctcaatctc tgtcaaggat aaacagccag
     2821 aggaagccag tcgtatcgct aattctctac gagaagttgc tgtagaaagg atcgtcgctg
     2881 taacgcgagt atctgatgta acgacacttg aagaagcgcg accagctacg actccttctt
     2941 ctccaaatgt tcgacgcaat tccttgtttg gttttcttgg aggagcagtt gtaacagtaa
     3001 ttgctgttct tttgattgag ttgttcgaca cccgtgtgaa acgtcctgaa gatgttgaag
     3061 atgtactgca aattccactt ttagggctcg ttccagattt ggacaaaatg aaataggagg
     3121 aagttatgcc aacattagaa atctcacagg caaaattgga ttttgtaaaa aaggcagagg
     3181 aatattataa ctctttgtgc atgaacctac agttaagtgg agatggtttg aaagtatttt
     3241 ctatcacttc tgtgaaacta ggagaaggaa aatcaacgac ttccaccaat atcgcttggg
     3301 cttttgcgcg tgcaggttac aaaacgctgc tgattgatgg agatattcgc aattctgtta
     3361 tgttaggtgt ctttaaagca agggataaga ttacaggcct gacagaattt ttatcaggaa
     3421 ctacagacct atcacaaggg ctttgtgata ccaatatcga aaatctcttt gtaattcagg
     3481 ctggctctgt gtcaccgaat ccgacagctc ttcttcaaag taagaatttc actacaatgc
     3541 ttgaaacctt gcgtaaatat tttgactaca tcattgtaga tactgctcct gtcggtgtcg
     3601 tgattgatgc ggctattatt acgcgaaaat gcgatgcttc tattttagtg acggaggcag
     3661 gtgaaataaa tcgacgggat attcaaaaag caaaagaaca gttggaacac acagggaagc
     3721 cgtttttggg agttgtgttg aataaattcg atacttcagt aaacaaatac ggttcttatg
     3781 gaaattatgg agattacggg aaaaataaaa aatagattga gggatagaga tgaatggaaa
     3841 agtagtaaat tcttcattgg ccataatcca tagttttctt gttattttat tgacttatct
     3901 acttagtgct gtgagagaag cggagattgc ttcagcaaca gctattgcac tttatatcct
     3961 ccattatttt gtcttttata tcagtgatta tggacaggat ttctttaaaa ggggatattt
     4021 gattgaactt gtccagacat tgaaatatat cctattcttt gcactagcga ttagtatttc
     4081 taattttttc ttagaggatc gatttagtat ttccagacga ggcatgattt acttcctcac
     4141 attacatgct ctcttagtct atgtgctaaa cctatttatc aagtggtatt ggaagcgggc
     4201 ttatcccaac tttaaaggaa gtaagaagat tctcctactt acagcaactt ctcgtgtcga
     4261 aaaggtactg gatagattaa tagaatcaaa tgaggttgtt ggggagttgg tagccgtcag
     4321 tgtcttagat aaaccagatt ttcagcatga ttgtttaaag gtagtagcag agggggagat
     4381 agtaaacttt gcgactcatg aggtggtcga tgaagtcttt atcaatcttc caagtgaaaa
     4441 atacaatatt ggagagcttg tctctcagtt tgaaacgatg ggaattgatg taacagtcaa
     4501 tctaaatgct tttgatcgta gtttggcacg taacaagcaa attcgtgaga tggcaggatt
     4561 aaacgttgtg attttttcta caacatttta taagactagc cacgtgattg ctaagcggat
     4621 tattgatatc gtgggtgcat tggtagggct gatactatgt ggtctagtca gtgttgtact
     4681 ggtccctttg attcgaaagg atgggggctc tgctattttt gctcagacgc gtattggaaa
     4741 aaatggtcgc cacttcactt tttacaagtt ccgctccatg tgtgtagatg ctgaggacaa
     4801 aaaaagagaa ctcatggaac aaaataccat gcagggtgga atgtttaagg tggatgatga
     4861 cccacgtatc acgaaagttg gtcgttttat acggaagact agcttggacg agctgccaca
     4921 gttttataat gttctaaagg gagatatgag tttggttggt acacgaccac caacagtgga
     4981 cgagtatgaa cactatactc cagaacaaaa acgtcgtcta agttttaaac ctggtataac
     5041 aggtttatgg caggttagtg gacgaagtga gattaagaat ttcgatgaag ttgtcaagtt
     5101 agatgtagct tatatagatg attggacaat ctggaaagat attgaaatct tattgaagac
     5161 agttaaagtt gtattgatga aggatggagc gaagtaaagg aatgaaaaat aaaaaaaaag
     5221 tatgtttttg tgcttcgtca gggggacatt atgagcaact aatgaagctt gaaccgatta
     5281 tgagacaaca agacagctat ttaatcacag aatatactga ttataacaaa ggagagtctg
     5341 agaagaaaga tataaacaag gtgttttatc ttttgcaaat taatcgtttg gaattttttt
     5401 ggatcgttaa attgatttgg atttccttga aatcacttta tatactgtta agaatacgcc
     5461 caaaagtagt tatctgtaca ggtgttcttg caatgatacc gttttgtttg ctttcaaaaa
     5521 tgtttggggc taaattaatt tatattgaat cttttgcaaa agtgaccact cctactttaa
     5581 caggtagaat actataccgt tacgcagata gattctatgt gcaatgggag agtatgctag
     5641 atatctaccc aaatgctgtt tataaagggg ggctttatta ggtgattttt ataactgtag
     5701 ggactcaaaa acaccctttt aatcgcttgt taaaaaaaat agatcaactt attgaattag
     5761 aagtgataaa ggaagaggtg tttgctcaga ttggagcttc tgattataaa cctaaatact
     5821 tttcttataa ttcatttttg agttcaattg atatgaatga gaagatgaga gaagctagta
     5881 tggtaattac acatggtggg actgctagta ttgttaaagc tttgaaatta agaaaaaaaa
     5941 ttatagcggt tccacgatta gagcagtttg gagaacatgt ggataatcac caattacaaa
     6001 tcatcacagt tcttggtgag gaaggttata ttttgccatg ctttgatata gagcagttag
     6061 gaactgttta tcaaaaagct cagactttta caacaaagcc atatatttct aatagttatg
     6121 cacttttaga agatatacga caatacatag atagtctttg aaaggaaatt tagatgacaa
     6181 aagttttgca aattgggcct agtataaatt tatctaaagg tggtatgagc gctgttatta
     6241 gagatttgac atatagcccg ttattgtcag gtgattttga tataactgct tatcaatctt
     6301 ttattgatgg ctctcttgta acacggttaa cctattctag ttatgctctt cttaaatttg
     6361 tagttcattc tggtaattat gacatatacc atattcacac tgctacaaga gggagttgtt
     6421 ggagaaaatt actgtatttg aaattactta aaagtaaaaa taaaaaagct attttgcata
     6481 ttcatggagc agaatttcaa atattttatg actcacttcc tgagtataaa aaaaataaag
     6541 tt
//
LOCUS       DBJKQU010000069         6227 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.069, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000069 DBJKQU010000000
VERSION     DBJKQU010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6227
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.069"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(<1..631)
                     /locus_tag="ACSUUC_001894"
     CDS             complement(<1..631)
                     /locus_tag="ACSUUC_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHQ8055046.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKI"
     gene            791..2545
                     /locus_tag="ACSUUC_001895"
     CDS             791..2545
                     /locus_tag="ACSUUC_001895"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8055047.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            2529..4250
                     /locus_tag="ACSUUC_001896"
     CDS             2529..4250
                     /locus_tag="ACSUUC_001896"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8055048.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            4261..4845
                     /locus_tag="ACSUUC_001897"
     CDS             4261..4845
                     /locus_tag="ACSUUC_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HHQ8055049.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            4845..5540
                     /locus_tag="ACSUUC_001898"
     CDS             4845..5540
                     /locus_tag="ACSUUC_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T family protein"
                     /protein_id="HHQ8055050.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            5528..>6227
                     /locus_tag="ACSUUC_001899"
     CDS             5528..>6227
                     /locus_tag="ACSUUC_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8055051.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKVEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNE"
BASE COUNT         2227 a          837 c         1118 g         2045 t
ORIGIN      
        1 caattttata tttttttcta tttaagtatg tgtcaattac tatacttatc cattcatttg
       61 cctttgcttt aaagaaaaaa tcagcggcag gagcgtccat cttacaattt aatatttcca
      121 ttgccactct ttctaaggcc tttgtaagta ttatttgatt cggttgaagc aaggttgaat
      181 aaaaagattc tggattaatg ttaatagatg ctaaatgttt ttctattagc tcttttttaa
      241 aaccaatgga aacagcaaga taacaacaat tctcgtgtaa taaaaaaaca aaatcatctt
      301 ttatattatc aaaatcaaaa gtacatagag agtttgcggt aatagtttga tacggattaa
      361 acttttctcc gtttgcactg acaatgtaac ttgaataaat tgaaacatag tctgacatac
      421 tataagtgct attttgaact acttcctctt tgatataaaa atcatgtata tcgataatga
      481 agctgcctcc ttcataaaac caatatagtc cttctgcata agttgaattc tcttttttcc
      541 aacaaaatgt atgacctgca cttgaatact tctcattgtt tttacattca tctactttca
      601 tataatcttt tacaaaatca taatatgaca taacacacta tcccttttag acaatattcc
      661 aattagcctt attaattcaa aactattgta ttagtaatta taacagatgt ataatagaaa
      721 agcaatgata gatattatca attaagcgaa tttatatcta aaagggatat taaagaaagg
      781 agatatgctt atgaagattt acaaaaaact atttgcttat gtccaagata agaaatatct
      841 tggggttttg gccataattt tttctgctat atctgctcta cttacagtat atggatatta
      901 tttaatctac aaatttctag ataagttaat aattaattca aacttatccg gtgcagagag
      961 tatagcatta aaatctgtta ttacactaac aagtggagcg atattttatt ttgtctcagg
     1021 aatgttttca catatcttgg gatttaggct tgaaacaaat ttaagaaaaa ggggaatcga
     1081 tggtctggaa aaagcaagtt ttaggttctt tgacttaaat ccatctggtc aaataagaaa
     1141 gatcatagat gataatgcag cacaaactca tcaggtggta gcacacatga ttcccgatag
     1201 ttctcaggca ataatcacac ccgtacttgt acttgcactt ggctttatag taagtataag
     1261 ggttggcata attttgcttg ctcttactat aattggtggc ttaattttag gggcaatgat
     1321 gggcgagcaa gaatttatga agatatacca agaatcccta tctaaactaa gtgctgaaac
     1381 tgttgagtac gtgagaggaa tgcaagttgt aaaaatattt aaagcaaatg tagagtcttt
     1441 taaaagcttt tataaggcga taaaagatta ctcaaagtat gcttatgatt attccctatc
     1501 ttgtaaaagg ccttatgttt tgtatcaatg gttatttttt ggactgattg caattttaat
     1561 tattcctata gtttatttta tgactagctt agctagcgca aaggtgattt tacttgagct
     1621 tatcatgatt ttatttttat caggagttct ctttgtttca ttcatgagaa tgatgtggta
     1681 ctccatgtat atttctcaag gaaattatgc agtagatact ttagaggcgc tttacgaaga
     1741 tatgcaaaaa gacaaattag tgcatggtaa tgtcaataat tttaaaaact ataatataga
     1801 atttgagaat gttagctttg cttataatga taaagctgtc attgaaaatt tatcctttaa
     1861 tttagaagaa ggaaagtcct acgcacttgt cggttcatct ggatcaggca aatcaacagt
     1921 agcaaaactt atatcaggtt tttacaatgt taataaagga agcataaaga taggcgggat
     1981 agcaataagt gaatattctg acgaagcctt aattaaagcc atttcctttg tttttcaaga
     2041 ttcaaaatta ttcaagaaga gcatttatga taatgtagct ttagctaata aagatgcgac
     2101 gaaagatgac gttatgagag ccttaaaatt agcaggatgc gatttaatat tagacaaatt
     2161 cccagaaaga gaaaatacaa tcataggctc aaaaggtgtt tatttatccg gtggagaaaa
     2221 acaaagaatt gcaattgcta gagcaatttt aaaggattcc aaaattatta ttatggatga
     2281 agcatcagca tctattgacc cagataacga gtttgaattg caaaaagctt ttaaaaatct
     2341 tatgaaggat aaaacagtta tcatgattgc acacaggcta tctacaatta aagaccttga
     2401 tgaaattatt gtcatggata gtggaaaaat tatagaaaga gggtctgaca aagaattaat
     2461 gtcaaaagat acaaggtata agagcctgca agagatgttt aacagtgcga atgaatggag
     2521 ggtttcaaat gaaagagttt tataaaaaaa gatttgctct tacagatgga ggagcaagaa
     2581 atttaagtaa agcaacactg gcttcatttt tcgtttattg tataaacatg cttcctgcca
     2641 tattacttat gatttttgct caggaagttt tggaaaatat gggcaaaagc aatggctttt
     2701 atatagtatt ctcagttttg actttgatag caatgtatat tttgctttct atcgaatacg
     2761 ataaattata taacacaacc tatcaagaaa gtgcagattt aagaataagg acagcggaga
     2821 atttatcaaa attacctcta tcttactttt ctaaacatga catttccgac atttcacaaa
     2881 caatcatggc tgatattgaa ggcatagagc atgcaatgag ccactcaata ccaaaggtgg
     2941 gcggcatggt actgtttttc ccattaatat ctgtaatgat gctagcgggc aatgtcaaga
     3001 tgggtttagc tgtaattatt ccatctattt taagctttat atttatacct ttatctaaaa
     3061 aatatcaggt taatggacag aatagatatt atgatgtctt aagaaaaaac tcagaaagct
     3121 ttcaagaaaa tatcgaaatg caaatggaga ttaaagcata taatttatcg aaggatatta
     3181 aagatgactt atataaaaaa atggaagata gtgagagagt acacttaaag gcggaagtaa
     3241 ctacaatttt aactttgtct atatcttcaa tatttagctt tatatctctt gctgttgtga
     3301 tatttgtcgg cgtaaatcta attattaata aagagataaa ttctctctac cttataggat
     3361 atttactagc tgctatgaag ataaaagact ctttagatgc atctaaagag ggcttgatgg
     3421 aaatatttta tttatcgccc aaaatagaaa gattaaaaga aattcaaaat caagatctac
     3481 aagaaggcga tgactatagc ttaaaaaaat ttgatattga tctaaaagat gttgagtttg
     3541 cctacaataa agacgcaaaa gttttaaatg gtgtaagttt taaagctaag cagggagagg
     3601 tcactgcttt ggtaggtgca agtggctgcg gtaaaacaac tatcttgaaa cttatatcaa
     3661 gactttatga ttatgacaag ggacaaatct taatcgatgg caaagatata aaagaaatat
     3721 caacagaatc tctttttgat aaggtctcta tagttttcca agatgtggtt ctctttaatc
     3781 aaagcgttat ggaaaatatt agaatcggaa agcaagatgc aagtgacgaa gaggttaaaa
     3841 gagcagcaaa acttgcaaat tgcacagatt ttatagaaaa aatggataaa ggtttcgata
     3901 cagttattgg tgagaacgga gctgagctat caggaggaga aagacaaaga ttatcaatag
     3961 ccagagcctt cttaaaagat gcgccgatat tgatcttaga tgagataaca gcaagccttg
     4021 atgttaacaa cgagaaaaag attcaagagt ctttaaataa tttagttaaa gataaaactg
     4081 ttgtaatcat ttcacataga atgaaatcca tagaaaatgc agacaagata gtagttcttc
     4141 aaaacggaag agtagaaagc gaaggtaagc atgaagagct tttacaaaaa tcaaaaattt
     4201 acaaaaattt aatagaaaag acaaaaatgg cagaagaatt tatttattag gaggactaca
     4261 atggataata aaaaattaaa agtaaaagat ttagtaagca tcggtgtttt tggcgtaatt
     4321 tattttgcct tcatgtttgg agttggtatg atgggcttga ttccaatatt gttcttaata
     4381 tacccgacag tattagccat agttgcagga actgttgtta tgttatttat ggctaaggtt
     4441 caaaagccat gggcactatt tatatttggt atgatatcac cacttgtgat gtttgcagct
     4501 ggtcatacct acgtagttgt ggttttatca cttatagtaa tgataatagc agaattaatt
     4561 agaaagattg gtaattataa ttcatttaaa tacaatatgc tttcttatgc aatcttcagc
     4621 acatggatat gtagctcttt aatgcaaatg cttttagcaa aagaaaaata tatggagtgg
     4681 tctttgatga cgatgggaaa agattatgtt gatgtattag aaaagttaat aacttatcct
     4741 cacatggctt tagtagcctt aggtgctttc ttaggaggaa ttcttggagc atatataggc
     4801 aaggctctat tgaaaaaaca ctttgaaaaa gcaggcattg tataatgcct actttttctt
     4861 caaatgctcc ctttaatccc aatccgatct ctaagatatt agtcgtattt atcacaggct
     4921 taactgttat gcatagcata aacatccgtt ttgagctggc aattgtttgt cttattggta
     4981 ttttgcttta tttgaatgga tacaaaaaaa cacttttcaa atggattata ttgtgtggga
     5041 tactttactc cttgcctaat tttatggtgt tatctgaatt aaaccctata gttaagatgt
     5101 ttttgagtat acctattgtt attagaatgt ttattttacc atttatggca gcaagcttta
     5161 tgataaagac ctcggatgta ggcgcaataa tttcatcgat ggataagctt aagatttcaa
     5221 agaatgtatc catacctatt gcggttatgt ttagattctt cccatctttt aaggaggaga
     5281 agaaaaacat caaaatggct atgagagtaa gagggataaa ttttaaaaac ccagtcaaat
     5341 atcttgaata tgtttctgtg ccactactca ttatatcatc taatatatca gatgacattg
     5401 caaaagcggc agaaacaaag gcaatagaaa atccaattgc caagaccaga tacattcgcg
     5461 taaagataca gctaattgat tttgtttatg ttttagcggt tgttggactt attgtgggag
     5521 gcttaatatg gttgaaataa aaaatttaag tcttgattat ggtgaagagc atatattaga
     5581 tgatatatca ctatccatag ccgagggaga gtgcgtgcta tttacaggaa aaagtggaaa
     5641 tggtaagtca tctttaataa attcaatcaa tggactagct gtaaggtatg ataacgcaaa
     5701 gacaaaggtc gaaataatta ttgatggtaa gaatataaaa aatttggaac tttatcaaat
     5761 ctcaatgctt gtttcaactg tttttcaaaa tcctaagaca tattttttta atgtcaatac
     5821 gacattagaa ttattatttt atttggaaaa tatcggtctt gcaagagaag agatggacag
     5881 gcgtttgaag gatatgcttg agatattccc gataaaaaat cttttgaaca gaaatatatt
     5941 taatctatcc ggcggtgaaa aacaaattct ttgcattgca gcttcttata tagcaggtac
     6001 aaagattata gttatggatg agccttcatc gaatttagat attaaaagca taagtgtttt
     6061 ggcaaagatg ctaaagatat taaaagagaa aggcataagc ataattgttg cagagcatag
     6121 aatttattat ttgatggaca tagttgaccg tgtattttta atagataaag gaaagcttaa
     6181 aaaaacttat actagaagtg aatttttaaa gctagataaa aatgaat
//
LOCUS       DBJKQU010000070         5090 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.070, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000070 DBJKQU010000000
VERSION     DBJKQU010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5090
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.070"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            88..1266
                     /locus_tag="ACSUUC_001900"
     CDS             88..1266
                     /locus_tag="ACSUUC_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055052.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLMFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLGRLVI
                     "
     gene            1475..>5090
                     /locus_tag="ACSUUC_001901"
     CDS             1475..>5090
                     /locus_tag="ACSUUC_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family
                     metallo-endopeptidase-related protein"
                     /protein_id="HHQ8055053.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALPEAVVTDKG
                     EPAVQPELPEAVVTDKGEPEVQPELPEAVVTDKGEPEVQPELPEAVVTDKGEPEVQPA
                     LPEAVVSDKGEPEQVAPLPEYTRPQAGAVVEPAIQPELPEAVVTDKGEPAVQPELPEA
                     VVTDKGETEVQPESPDTVVSDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQ
                     AGSIVEPEKVEAPKEYTGKIEQPSAEDTKPENEASSTNGESERPKDKIKEEKQVDKKL
                     ELRNVSNVELYTVENNKYRHITAVDGALDSSLKYFMKVKSENFKDIMLPVTKIESTTK
                     NNKEVYKIVAHAENLIQHENNVISNDYTYYLPKTQQSETGVYTSFKNLVDAMNSDPNG
                     TFHLGATMDAREVELPDDQESYVKNEFYGKLIGENNGKYYAIYNLKKPLFKTLNTATI
                     QNLSIKEANVSSKEDAATISKEAKYNTLIDNVHSDGIIAGERGIGGLVSKVDNSRISN
                     SSFTGRITNTYDTTVGYEIGGLVGKLSGSLASIEKSIASIDIASNAKSGDQIVGGIAG
                     VVEKSATIKYSYVEGNVNNVRHFGKVGGVAGNLWDRDSQDVSKSGKLSYVLSDVNVTN
                     GNAISGDNFDNMKEDHAYSSKGNKVVNVVQVDDELVTKDSDVQRGTVLDADKVKEKKA
                     ELVSKHSTKVEDFDFTSRYTTIYNEVTGYQKSREQVYKNIEKLLPFYNRETIVKYGNL
                     VDESSELFTKELLSVVPMKNNEVITDINKNKQEINKLLLHFEGNKSQVLNIAYKNDFS
                     K"
BASE COUNT         1887 a          834 c         1037 g         1332 t
ORIGIN      
        1 acaacctcaa aacagtgttt tgagctgact gcggctagct ttctagtttg ctctttgatt
       61 tttattgagt attagaaagg agacctcatg acacttccag ttagaaaatc cctgcacgat
      121 gcagttttac aggcttcgaa agcggatact tgggaacaag ctaccaagga atggaatgaa
      181 gtttccttga tgtttaacgg tatcggccgt agcaattgtg tctgtggaaa tgccatcaaa
      241 tacgcttatg aactctttaa cggtgtcaca ggccaacgcc tctttccaat tggtagcgac
      301 tgtgttcgtc attttcatcg attgtccctt gaccagcaat tggaagagga agaaaaactg
      361 ctcagaaagg ttgaaaatct aaccagaaaa gctcagaaaa aggaaaaaat caaggtcaat
      421 aaaagtgact ttgacgagcg acttctaaaa tggctctggg aaaaaggtgt tttcaaaccc
      481 aatcgtggca atcaatttgc gcctgagaga gactaccagc ttttcctaga agtctttcag
      541 ggaggaagtt ggaccaaggc ggaaccaaag aaaaaggctc ggatggaaga agtccttgaa
      601 aagtgtatca aaccattttt acttgggaaa tcggatgacc aactctacct tgtcaagcta
      661 ggcaaggaga aaattgacta cgaacaagaa ctccgtatcc aggcagagaa agaacgcaag
      721 aagagggata aaatcgccaa gcaatatgca gataatctgg ttctagccat gggacccgca
      781 gagcgtgctt atcaagatta ctttggcttt acagagaccc tgactcaaga agaacgcaag
      841 tgggaaaaaa ttctttttgg taaaaataga gcagaacggg ctatcaaggc caaacaatac
      901 caaaaagagc tggaaaaaga ccaacgaatt gccagtcagg atccaattga aagaaaacag
      961 aagcagactt ggctcctcaa ttcctatttt cgagagcttc ctgaagaaaa agctcgattt
     1021 tctaggctct tattagaata tcgaaaaagt ggtgaagtac ccttttcaac tgaatacctg
     1081 tcagatcatc tcatcgactt tttctataaa atgaaagcct ttgaatttga aatcgcacca
     1141 gaacaagtcc gagattttct aaaaaaaagc ctgcaggaag accatcgctc atcagcacaa
     1201 ggaagctgga tagaaggaat tctcctcaac tgcctcaaac catttttagg acgattagtg
     1261 atatgagtaa cacctaccgt gtaaatttca tggtaggtgt tattgtaccc caaaataata
     1321 taaaacaaag tatgaaagcg catctcaatt ttaagacttt tttgtaaatt aagagtataa
     1381 ttaaggtata ctgccttttc tatagataat agataataca ctaatataat aaaggtcttt
     1441 gtaacatata taaattttat ttcaaggagg aataatggaa aagtattttg gtgaaaaaca
     1501 agagcgtttt tcatttagaa aattatcagt aggacttgta tctgcaacga tttcaagttt
     1561 attttttatg tctgtattag ctagttcatc tgtggatgct caagaaactg cgggagttca
     1621 ctataaatat gtggcagatt cagagctatc atcagaagaa aagaagcagc ttgtctatga
     1681 tattccgaca tacgtggaga atgatgatga aacttattat cttgtttata agttaaattc
     1741 tcaaaatcaa ctggcggaat taccaaatac tggaagcaag aatgagaggc aagccctagt
     1801 tgctggtgct agcttagctg ctctgggaat tttaattttt gctgtttcca agaaaaaggt
     1861 taagaataaa acggtattac atttagtatt ggttgcggga ataggaaatg gtgtcttagt
     1921 ttcagtccat gctttagaaa atcatctttt gctaaattac aatacggact atgaattgac
     1981 ctctggagaa aaattacctc ttcctaaaga gatttcaggt tacacttata ttggatatat
     2041 caaagaggga aaaacgactt ctgattttga agtaagtaat caagaaaaat cagcagccac
     2101 tcctacaaaa caacaaaagg tggattataa tgttacacca aattttgtag accatccatc
     2161 aacagtacaa gctattcagg aacaaacacc tgtttcttca actaagccga cagaagttca
     2221 agtagttgaa aaacctttct ctactgaatt aatcaatcca agaaaagaag agaaacaatc
     2281 ttcagattct caagaacaat tagccgaaca taagaatcta gaaacgaaga aagaggagaa
     2341 gatttctcca aaagaaaaga ctggggtaaa tacattaaat ccacaggatg aagttttatc
     2401 aggtcaattg aacaaacctg aactcttata tcgtgaggaa actatagaga caaaaataga
     2461 ttttcaagaa gaaattcaag aaaatcctga tttagctgaa ggaactgtaa gagtaaaaca
     2521 agaaggtaaa ttaggtaaga aagttgaaat cgtcagaata ttctctgtaa acaaggaaga
     2581 agtttcgcga gaaattgttt cgacttcaac gactgcgcct attccaagaa tagtcgaaaa
     2641 aggtactaaa aaaactcaag ttataaagga acaacctgag actggtgtag aacataagga
     2701 cgtacagtct ggagctattg ttgaacccgc aattcagcct gagttgccag aagctgtagt
     2761 aagtgataaa ggcgtaccag aagttcaacc agcgttaccg gaagcagtcg taaccgacaa
     2821 aggtgagccc gctgtccaac ctgaattacc cgaagctgtt gtaactgaca aaggcgagcc
     2881 tgaagttcaa cctgaattac ccgaagctgt tgtaactgac aaaggcgagc ctgaagttca
     2941 acctgaatta cccgaagctg ttgtaactga caaaggcgag cctgaagttc aaccagcgtt
     3001 acccgaagcg gttgtaagtg ataaaggtga accagagcag gtagccccat tgccagaata
     3061 tacaagacca caagcaggtg cagtagttga acctgcaatc caaccagagt taccagaagc
     3121 tgttgtaact gacaaaggag aaccagcagt ccaaccagag ctaccggaag cggttgtaac
     3181 tgacaaaggt gagactgagg ttcaaccaga gtcgccagat actgtggtaa gtgataaagg
     3241 tgaacctaaa caggtagcac cgcttccaga atatacagga ccacaagcca gcgctattgt
     3301 tgaaccagag caagtagcac cactaccaga atacacaggg gtacaagccg gatcgatagt
     3361 cgagccagag aaagtagaag caccgaaaga atatactggt aaaatcgaac aacctagtgc
     3421 agaagatact aaacctgaaa atgaggcaag ctctacaaat ggggaatcgg aacgtcctaa
     3481 agataaaatt aaagaagaaa aacaagtcga caagaaacta gaacttagaa atgtttcaaa
     3541 cgtggaatta tatacggtag aaaataataa atatcgacat attacggctg tagatggtgc
     3601 tttagatagt tcattgaagt atttcatgaa ggtaaaatca gaaaatttta aagatataat
     3661 gttgcctgtt actaaaattg aaagtacaac aaaaaacaat aaagaagtat acaaaattgt
     3721 ggctcatgca gaaaatctaa ttcaacacga aaacaatgtt atttcgaatg actatacata
     3781 ttatttacca aaaactcagc aaagtgaaac tggcgtctat acatcattta aaaatttagt
     3841 tgatgcaatg aatagtgacc ctaatggaac attccattta ggtgcaacta tggatgctcg
     3901 tgaagttgaa cttccggatg atcaagaaag ttatgtaaaa aatgaatttt acggaaaatt
     3961 aataggtgaa aataatggta agtattatgc tatttataac ttgaaaaaac ctttatttaa
     4021 aactctaaac accgctacta ttcagaatct ttcaataaaa gaagcgaatg tttcttctaa
     4081 agaagatgct gctacaatat cgaaagaagc aaaatacaat actcttatag ataatgttca
     4141 ttctgatggt attatagctg gtgaacgtgg aattggtgga ttggtttcaa aagtagataa
     4201 ctcgagaatt tctaatagta gttttacagg cagaataact aacacatatg atacaactgt
     4261 agggtatgaa attggtggtt tagtaggtaa actttctggt tcgcttgctt ctatagagaa
     4321 atcaatagca tcgattgaca tagcctctaa tgcaaaatca ggagatcaaa ttgttggtgg
     4381 tatagccgga gttgttgaga aaagtgcgac aattaagtat agctatgttg aaggaaatgt
     4441 taacaatgtg cgacactttg gtaaagttgg gggagttgca ggtaatcttt gggatagaga
     4501 ttcacaagat gtaagtaaat caggtaaact atcatatgtt ttaagtgatg ttaatgtaac
     4561 aaatggtaat gctatatcgg gtgataattt tgataatatg aaagaagatc atgcttatag
     4621 tagtaaaggc aataaagtag taaatgtagt ccaagtagat gatgaacttg tgactaaaga
     4681 ttcagatgta caaagaggta cggtattaga tgctgataaa gtaaaagaga aaaaggcaga
     4741 attggtttcc aaacacagca ctaaagtaga agattttgat ttcacttcaa gatacactac
     4801 tatttacaat gaagtaacag gttatcaaaa gtcgagagaa caagtatata aaaatattga
     4861 aaaactatta ccgttctata atcgagagac aattgttaaa tatggtaatt tagtagatga
     4921 aagcagcgag ctatttacta aagaacttct atcagttgtt cctatgaaga ataatgaagt
     4981 aataactgat attaataaaa ataaacaaga aataaacaaa ttgttattac attttgaagg
     5041 taataaatca caagtattaa atattgcata taagaatgat ttctctaaag
//
LOCUS       DBJKQU010000071         4741 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.071, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000071 DBJKQU010000000
VERSION     DBJKQU010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.071"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(366..1094)
                     /locus_tag="ACSUUC_001902"
     CDS             complement(366..1094)
                     /locus_tag="ACSUUC_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHQ8055054.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1252..2661
                     /locus_tag="ACSUUC_001903"
     CDS             1252..2661
                     /locus_tag="ACSUUC_001903"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHQ8055055.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2679..3974
                     /locus_tag="ACSUUC_001904"
     CDS             2679..3974
                     /locus_tag="ACSUUC_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHQ8055056.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIRVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3979..4287
                     /locus_tag="ACSUUC_001905"
     CDS             3979..4287
                     /locus_tag="ACSUUC_001905"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHQ8055057.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4284..4592
                     /locus_tag="ACSUUC_001906"
     CDS             4284..4592
                     /locus_tag="ACSUUC_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHQ8055058.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1602 a          811 c          873 g         1455 t
ORIGIN      
        1 ataaattggg agattgaaat tcatttctag caatttttta gaagtcacag tctactattc
       61 taacctcagt atactatatg tgttacaaga aaagactcaa aaacttctcg tcagtgtaag
      121 aatgtttgaa acaccattta aaactaaata actataagaa gtagatcagg tgaacaattt
      181 cagtacctac tctataagct atacgaagat atttttcaac atgatggata aaacgatcac
      241 tcttttaaag ccatcttatt tagaaaagag aaaccattta agcatagatg ggaccttctt
      301 gccctgtttt aaatttttct taaactagag tctgtaaaag attggcttca ttttcacatt
      361 ttctcctagg aggaatgtcg taatgcaaaa gaattaaatt caaataaatc atagcgatga
      421 cgactaatcg agtactcaaa cggagttccg ttatccaaat aagccacttg ttctacttca
      481 aataccggtt ccgttggaag gagctgcaag taatgttgct cattttctga actagaagaa
      541 gctcgcaaga tttttgtagc actggcaata tgcaatccta actttccttc aatgtaattg
      601 taaatcgatt tttgtaaaat atcttcagta atacctggaa taacatcggt actcatataa
      661 gtttgttcca gaacataagg tttaccgtca ataatacgca gacggtaaat attataaact
      721 ggactctgca aagcgacctg tagtttttct gctaaaaatt catttgcaaa ttctaatttg
      781 aagtgaataa tcctcgagtc aattgtagaa tgagcatctt cagatatttt tgtcagtccc
      841 cggatatctc tttctggaac gattaatttt ctttttgagc tgccacgaga gagaacaaag
      901 gttccctgcc cacgttttct aaaaattaag ccctcagaaa ctaacaagtc taaagctttt
      961 ttgatcgtca ttcgactaca ggcaaactgt ttagctaatg tcatttcatc aggcaattgt
     1021 tcgttcatgg tatatttatt acaaagaatc ttttcacgaa tctcattgta aataaataaa
     1081 tattttgtac tcatttaatc tggttctctc tataatattc taatagtagt ataacaaagt
     1141 tcaagaaatg aggcaaacac aagatatgta tcaacaattt ttaaaaatgt ctagacaaat
     1201 tttaaaatta tgctatactt tatgtataga ataatagaaa ggaggttgag catgaaaaaa
     1261 aagttagtat ttcctaatct gttttggtgg ggagctgctt ctagcggacc tcagacagaa
     1321 ggtcaatatg gaaaagtaca tgaaaatgtg atggactact ggttcaaaac gcatccagaa
     1381 gattttttcg ataatgtcgg acctcttgta gccagtaact tttttcatac ttacaccgaa
     1441 gatttccact tgatgaagga aattggagtt aattctttcc gcacttccat ccaatggagt
     1501 cgactcatca agaatttaga gacaggtgag cctgatccaa aaggtattgc tttctacaat
     1561 gccatcattg aagaagctaa aaagaaccag atggatcttg tgatgaattt acatcatttt
     1621 gatttaccag tggaacttct tcaaaaatac ggtggttggg aaagcaaaca tgtagtggag
     1681 ttattcgtga agtttgccaa gactgctttc acatgctttg gagataaggt tcattactgg
     1741 acaactttca atgagccaat ggtcattcca gaagcaggat acttatatgc tttccattat
     1801 ccaaatctaa aaggaaaggg aaaagaggcc gtacaagtca tctataatct aaaccttgct
     1861 agtgcaaaag tgattcaact atatcgctca ttagaacttg atggaaagat tgggattatt
     1921 ttaaacttga cacctgctta tccaagaagt aattctccag aagacttaga agcaagtcga
     1981 tttacagatg acttctttaa caaagtcttc ttgaatccag ctgttaaagg aactttccca
     2041 gaaagattgg taaaacagct agagagagat ggcgtgttat ggagtcatac cgaaaaagag
     2101 cttcaactga tgaaatcaaa tacggttgat tttcttggag taaactacta ccatccaaaa
     2161 cgtgttcaag cacaagcaaa tcctgaggaa tatcagacgc cctggatgcc agaccaatac
     2221 ttcaaagagt atgaatggct ggagcgtcgc atgaatccat atcgtggttg ggaaattttt
     2281 ccgaaagcca tttatgatat tgctatgatt gtgaaggaag aatatggtaa tatcccatgg
     2341 tttatcagtg aaaacggaat gggtgttgaa aacgaagcac ggtttatcga tgaaaatgga
     2401 gttatcgatg acgtgtatcg tattgaattt tatgaagaac atttaagatg gctacataaa
     2461 gccattgaag agggaagtca ctgttttgga taccacgctt ggaccgcatt tgattgctgg
     2521 tcttggaata atgcatataa gaatcgttac ggatttatct ccgttgattt agaaacgcaa
     2581 aagagaacca tcaagagctc aggaagatgg tatcgcaaag taagtgacaa taacggtttt
     2641 gaagtagaaa ttgaggagta aagagaggag atattcatat gaaaaactca aaatttatag
     2701 accaatttgc cacctttgct ggtaaactag ggaaccaaat tcatttaaaa accctaagag
     2761 atgcattcgt aacagtaatg ccattatata ttttggcagg tttaatcgtt cttttgaaca
     2821 acacggtatt taagtggatt ttccaagggg atacattaac aagattccaa tattggggaa
     2881 taacaattgc aaacggtact ttaagtattt caggtatgat tattgctgta atggttggtt
     2941 atttcttagc taaaaacaga gatttcgaaa acccgttagc agcatcaatg ctatcattag
     3001 tttctttaat tgtgatgatg ccaaatacag tttctgtagt tcctgacgga gcaaaagatg
     3061 cggtaaacat ttcaggtgtt ctttcattca acaacacagg tacaggcgca atgttcgccg
     3121 gggttatcgt agcgattatt gcaacagaat tattcattga attatcaaac gttaaagctt
     3181 tacaaatgaa ccttggtgaa aatattccac cagctgttag tagatcattt agcgtattac
     3241 ttccagtcat gaccgtcatc tccttatttg gggttgtttc agcattatta ttcaatataa
     3301 ctggaatgaa cttaatctca atcattacaa tctttattca agaaccaatt cgtcatattg
     3361 gtacaagctt aatcagggtc attattattt actctttagg aaatatgtta tggctatttg
     3421 gtattcacca agcagttatt tacagtgcca tcctagaacc attactatta attaacatta
     3481 ctgaaaacat cactgcagca aataatggac aagccattcc acacatcatc aacctatcac
     3541 aaatacaaac attcgcttta atgggtggta gtggatctac attatgttta ttaatagcaa
     3601 cattcttagt gagtcgcaat gctgtctcta aaaacgtggc taaattatct tttggacctg
     3661 gtatcttcaa tatcaatgaa ccagtattat tcggttaccc aatcgtttat aacatttcat
     3721 tagctattcc atttatcaca gttccagtcc ttggtatttt aatcagctac ttagcaacag
     3781 ttacaggatt catgagtcct gcatttatac aagttccttg gactacacca gtattcttaa
     3841 atgcatggtt agcaacagca ggggacgtga gagcagttct agttcaattc atcatctttg
     3901 cacttggagt tcttctatac attccattta tcaaagttaa tgacaaagtt gttgaacaag
     3961 aaatggaagg ttaagattat gaaacaaatt ttattagtat gtaatgcggg aatgtcgaca
     4021 agtatgcttg ttaaaaaaat gcaacaaagt gcgactgaac gtgggattga aatctctatc
     4081 caagcaaaat caatgacaga agctaaaaag aatatccatg aagcagatgt cattctaatt
     4141 gggccacaaa ttcgttatga gttacttgct gtgaaagaaa ttgcaggaaa tatccctgta
     4201 gataccattg atatgcggga ttacggaatg atgaatggag caaaagttct ggaacaagca
     4261 cttgcatgga taggagaaat aagatgacag aagaaatgga atatatctgt tttcagctca
     4321 ttgccaatag tggagcagcc aaatcatcct ttattgaagc catccaacta gctaaggcag
     4381 gaaatttaaa agaagcgaaa attaaagttg aagaagcgga agactcctta gtagaagcgc
     4441 acaagattca ctctaatctc atacaaaaag aagctactgg agaaaaaata ggattctcct
     4501 tgctatttat gcatgcagaa gaccaaatgg cttcaacaga gattattcag ttgctatcta
     4561 aagaattcat cgatctctat caaaataaat aggaacactg tcattcccat ctgtctttat
     4621 taatgacgac tacattgtag gaacctccaa aagttggaca aaatgattga aaggattgga
     4681 tcctgcatta cacaagatcc aatccttttc ttttactcta gtttttataa tatgttgaat
     4741 c
//
LOCUS       DBJKQU010000072         4736 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.072, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000072 DBJKQU010000000
VERSION     DBJKQU010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4736
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.072"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..193
                     /locus_tag="ACSUUC_001907"
     CDS             <1..193
                     /locus_tag="ACSUUC_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP binding domain-containing protein"
                     /protein_id="HHQ8055059.1"
                     /translation="LLIVGIKILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWD
                     RGLEAYKDKVYTRGIWIRD"
     gene            588..1451
                     /locus_tag="ACSUUC_001908"
     CDS             588..1451
                     /locus_tag="ACSUUC_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HHQ8055060.1"
                     /translation="MIERMELGEFYKELRLARKLKQSDVTCAGLTTSQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRFGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKLLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            1737..1970
                     /locus_tag="ACSUUC_001909"
     CDS             1737..1970
                     /locus_tag="ACSUUC_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055061.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            1992..2669
                     /locus_tag="ACSUUC_001910"
     CDS             1992..2669
                     /locus_tag="ACSUUC_001910"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHQ8055062.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWFYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            2681..3346
                     /locus_tag="ACSUUC_001911"
     CDS             2681..3346
                     /locus_tag="ACSUUC_001911"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HHQ8055063.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTVLEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            3418..4644
                     /locus_tag="ACSUUC_001912"
     CDS             3418..4644
                     /locus_tag="ACSUUC_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHQ8055064.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         1343 a          810 c          924 g         1659 t
ORIGIN      
        1 actattgatt gtcggtataa aaattttagt atatgaacca aatttaaacg ttagtataga
       61 taacgtaatt tttgaaaaga attttgaact atttacaaaa caaagtgatc taattgttgc
      121 aaatagatgg gataggggcc ttgaagctta taaagataaa gtttacacaa gggggatctg
      181 gataagagat taactattga tattaaaaag gcaataattt ataaaatttg tacaaaaaaa
      241 tgttaaattt tcacattttc atagtatact gtttaataga aagtaggttc tttgtaaccg
      301 ctccattata aaatcctttc actcttccgg tatactatta ggaaaaacat aactggagga
      361 tattttgagc tcacacctca tcgttccagt ggctgttccc caagctcgtg tactgtccaa
      421 aaaagttaga cattctattt agaacgagga ttgagttctg tattgtacaa ggctcggtcc
      481 ttttagagtc agcttaaggc tggctttttc aatcaccaaa gtgtcagaat gttttgacaa
      541 aactataaaa acaatgatat actatataaa aaataggagg tggtgagatg atcgagagaa
      601 tggaattggg agaattttac aaagaactgc gcctggctag aaagctcaag cagtcagatg
      661 tgacttgtgc tggtctaaca acctctcagt tgtccaagtt tgaactaggg cagtctatgt
      721 tgtctgcaga taagctcata ttagccatcc aagggatcaa tatgaatttt gatgagtttg
      781 ggcacaagct caacaactat caagaatctc cacatatgcg atttggtaga aaggttgtgg
      841 atcgctttgc tcatcaagat atagctggct tagagcaact gttggaggaa gtcgagcaag
      901 aacagatggc agagacttat cgtcgtttga atgctattgt aatcaaagat gccatccact
      961 cactagataa aagctaccca ctagcagagg aggatagcga gtttttgacc acctatctct
     1021 atgctatcga gtcttggacc tggtttgaac tctatctctt ttgcaatact atgcccttct
     1081 tgagcaatca agatctgatc tttttatcaa cctccttact cgaaaaatcc aaagaattta
     1141 aagagttagt acacaatcga ttgtatatga agcaaggact cttaaatatc atctcagagc
     1201 tcatggagcg caaacttttt tcttatatcc caatctttga agccgagctg gagagtatgc
     1261 tccgtccata cgatgttttt gagaaattat tgtggcagtt tttaaagaag atgagcattt
     1321 tccttcaaac taagggaagc aatcaaaaag agattgaaca ctttatccaa tctctgcaag
     1381 tattagaaaa tccacaatta atagcccttt ttgaattgcg tttgcagcaa tacaaaaagc
     1441 ttatcgatta gttagaaatg gcaaaataat aataatctca gcaacgattt tcaataatgt
     1501 taaaatttgt ttcttcatat ttctccactc ctcattagta gtaactttat tataccagag
     1561 aagtaatcaa attcaccaaa atcgcaaatc tgaaatttct ataagaaaaa atatcaaata
     1621 tgcgattttc taaaataagc caattttcgt gttatactgt acttgtaaag cacttgaagc
     1681 aaatcctagg tcgcagaagt ggtttacaaa tgaagataat tgaaggagtg taaaagatgt
     1741 taaatttaca atttgcagaa acaatggaat tgacagaagc tgagttgcaa gatgttagag
     1801 gaggcaacct cgtaaattct atgggaggtg gtggaagaag tggtatatct ggttggggcg
     1861 tcccaggaat ttaccctggt tggggcaatc aagggatgag tcctaatcgt ggagcttttg
     1921 attggactat agatttagca gatggattgt ttggccgccg tagaagatag gctcttatag
     1981 gagataatag gatgaagaaa atgaaagaag tgaaatttca cctagcaact ggcttgttga
     2041 ttttgactta ttacctcatt tttaatgtca catcagactt agattttatg gttgctttgt
     2101 ctgataatat gtactatgtg ttccaagttt tattggtact tattctggga actatagcta
     2161 caattgcttt tgtcaaaagt gaacattgga aagagtgtgg tcgtttccag tttcgttggt
     2221 tttacctggg tgttttcctt ctttcttttt tcttattgtt cgtgtgggca aatctaacaa
     2281 cctatatctt tcctcgtacc cagaatggaa gtacagtcgt agaagtagcc accaatttaa
     2341 caggaattag ctattttgtt acgcgaatac tttatactag tattatcgca cctgtatcag
     2401 aagaggttgt ttgtcgtggt cttttgatga caagtttatc taaagttaag agatactatc
     2461 ttgatgttct tgtttccgct gccatatttg gcgctatgca tgttttgcag tatggttgga
     2521 taacgacaga tttcataaag tattttggaa tgggcttgat attttgtatg atgtttcgct
     2581 acacccgatc catctattgg gctatagctc tgcatgcttc atggaatagt ttcttactca
     2641 ttgttacttt attggtattt ggatattaga aaggtgatat atgaaaaaga taatctcaca
     2701 ccgctacttt attatagttt ttctactagt tattgctgac cagaagttca gtgttctagt
     2761 tttacgcagc gaccttgtta ctgggctatc tgactttgcc tattatctgt cggatatgat
     2821 gttgaatttt cttgtggttt tatttgctct tattgctatg atttggtcgg ggaaatggca
     2881 gaaaatcaat agtagaaagt ttaaaggatc ctatcttttc tattccttcc tagctctgct
     2941 tgcttttgtt gtttggaatt tcgttacctt ttttcttttc ccacctactc gaaatgaaat
     3001 ttcttatcaa catgctgctc cgacttttac aggggctaca gcatttttga tgtatttttt
     3061 ctatcctgtg attgcaggtc ccatttttga agagataatc catcggggat tggtgatgac
     3121 agttctggaa aaaggaaaga aatgggggct agatgtactt ggttccgctg ttttatttgg
     3181 ggtctcgcac attagtaatc acggttgggt cttgacagac tttgtcttct atatgggtgg
     3241 aggtcttata tttgcagtct tatttagaat gacaaagtca atttattggc ctattggact
     3301 gcatatagtc tacaatggca ttggtcagct tttgatgtta ctgtaatttt ggttgttagt
     3361 agtatcgcgg tctatccttg gggaaagctt cccatttgaa cttaagaagg agttgtgatg
     3421 aaagtatttc ttcaaaatag agattttagg caattaacta tcaaccagtg gatttcaacg
     3481 cttggggata cgatttttta tctggccttc ctgaattatg tggcagatgc atcttttgcc
     3541 cctttggcga ttttactcat cacgatttca gaaaccctgc cccaagttct acaaatcttt
     3601 ctgggagttt tggcggattt tcaacatcat cgtgtcttga aatacacagt cattagtttt
     3661 gcaaaatttt tgctttactc tatagtgtct ttatcacttt cagggcagtc cttttccttg
     3721 ttattagtag catttatttg tctgattaac cttttgtctg acacgttgag ttatttttca
     3781 ggcgccatgc tcactccgat tttcattaga attattgggc aagaccatct ggcagaagct
     3841 attggattta aacagtcaac tgttagttta gtgaaaacaa tcagtaatat tctaggagga
     3901 gtcttattag gtattctatc catccagttt atttccttgc tgaacgctct taccttttta
     3961 atcgcatttt taggtatcct cttcataaaa actgacctct tgaaagtaga aaaaacgatt
     4021 aactatcaag aaggactctc tgtaaaatcc ttttgccagc atttgctcca atcatcgaaa
     4081 ttgatatgga atatgaataa ggtgctcttg gttttgttta ttatctctac tagtcaagca
     4141 gtgataaatg ttacagttcc tgtctctact ctatttttga ggaatcaacc ctttttgaat
     4201 ttacaaacag gtcaatctct tgccttgcta tccacttttg aactgtcagc cctgattgtc
     4261 ggaagccttg taagtggcta tctgcaacat accatttcca taaaaacagc tctctatgcc
     4321 tcacttgtca tccagttgct tcttctagta ggatttgcca cagttcgttt tgactggatt
     4381 ctcatcttta gtaccttgga tgcctttttc gcaggtgttc tctctcctag attgcaagaa
     4441 ctcgtcttta aacaaatacc tgaggagtca atgggagcag ttcaatcttc tatcagtgcc
     4501 attacggttg ttttacctag cttatttaca atatctttgg taaccattgc tactagcttt
     4561 ggaactctgg cagttagctt tgttttattg ctatttcttc tagttgcctt tgttatgctt
     4621 ctgaatattc gtgaaagtat ttagtggaga atttctataa tatatgtttg agactggatt
     4681 gccagtcttt ttatgatggt caaaatcaac agactttttt ctcttttctg aatgtg
//
LOCUS       DBJKQU010000073         4697 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.073, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000073 DBJKQU010000000
VERSION     DBJKQU010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4697
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.073"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            128..1306
                     /locus_tag="ACSUUC_001913"
     CDS             128..1306
                     /locus_tag="ACSUUC_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HHQ8055065.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(1534..1980)
                     /locus_tag="ACSUUC_001914"
     CDS             complement(1534..1980)
                     /locus_tag="ACSUUC_001914"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8055066.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLPLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            2050..2709
                     /locus_tag="ACSUUC_001915"
     CDS             2050..2709
                     /locus_tag="ACSUUC_001915"
                     /EC_number="3.4.23.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HHQ8055067.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(2761..3912)
                     /locus_tag="ACSUUC_001916"
     CDS             complement(2761..3912)
                     /locus_tag="ACSUUC_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHQ8055068.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(3927..4658)
                     /locus_tag="ACSUUC_001917"
     CDS             complement(3927..4658)
                     /locus_tag="ACSUUC_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055069.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
BASE COUNT         1459 a          926 c          694 g         1618 t
ORIGIN      
        1 ttattatcaa tatataataa aaagagacca gtaagcaatg aaaagcttaa aaagattaac
       61 atctacattt atccatagca aaaaatcata ggattttaag aatctgacaa ctaggaagaa
      121 aactaatatg accttatcta agaaacaatt acaactaaga gctaaaatac tggaaacagt
      181 ttacacatta ggtcccattt cacgaattga aatcgctact aaaacaggaa taacacctgc
      241 aacaactagc agtatcacaa atgatctgat taaagaaaat attctcttag aacttggtga
      301 agacgaacac gatacaagcg tagggagaaa aaaaatcctg ctagacattc aagctaaacg
      361 attttactac attggttgtg aactatctga aaaacatttc acttttgctt taggagataa
      421 tctaggaaat atcttaaagg aagagaaaga aattgttact aaacagttaa tccaagaaaa
      481 gggaaatcaa ctcattaacc agacactaaa gcaattctta aataactgct ctgattatga
      541 aatagaagca attggaatcg cgctacctgg tcgctattta gatgattata aaataacaac
      601 aaacaatcct ttatggcaac atatcgactt agaaatgatt caatcccact ttgataagcc
      661 tttgtttttc tctaacaatg ttaactgtat ggctataggt aaacgcctat ttagtcgcca
      721 acagaatgac cctaattttg cttattttca ttttgctaga ggtatgcact gttcttatat
      781 ctacgacgga aacatttatg ggaaaggaaa tctaatgatt ggagaaatag ggcatacagt
      841 tgtttcatct gagggagaag aatgtagctg cgggcgcaag ggatgcttac aaacttttgc
      901 tggagaatct tggttaatca aaaaatcaaa aattctatat catcaatctc cctattctct
      961 acttcctagt ttagtcaaaa atgccgatga tattgatatc caagttattt taaccgctta
     1021 tcaattaggt gacactggaa taatcacact tatccatcaa gccttactct atcttagtca
     1081 aaccatttta aatatcagta tgatgattga ctctcaaaaa atctacctac atagtccttt
     1141 actaacaaat caacacatca tccaaaaact atatagtgaa atgaactaca aacccaaact
     1201 gctctataat cgcctacctg aagtcattat tgaaccttac aatgatttta cagccgcaca
     1261 ctcagctatt gcactttgtt tgtatcatac aattctacat tcttaatttt ctattacatt
     1321 taataaatag gctaaaaaga gggagtatat cataaaaagc gaataaacct gttttctgaa
     1381 aatcagaatt ctgttttgtt cgctttcttt atatttggaa ttatactcct atctcccctt
     1441 tttcataatg tatagtgaaa tgaaataata acaggacgaa tcgatcggga cagtcaaatc
     1501 gatttctaac aatgttttag aaatagaggt gtactattct agtttcaatc cactatattt
     1561 tcgtacaggt gcttcaacca tttgaacgat ttcaaatcct tctttttggt aaagattctg
     1621 agctctttga tttgcctcga agacatttag agaaatacta tctatatctt cattttcaaa
     1681 ggccaaacta acaaatttcc ttaaagcctg gctacctaag tcttgctcct gtttctgggg
     1741 gttgataaaa aatctcccga tatgaagatt gctgtcttct agcctgattt tctggataag
     1801 tcccacaaac tcttgttcat caaagattga aaagactcct tccaaggctt gaaggggcag
     1861 tagaaaagga atccttggtc ccatccattg ttcttgaaag gatttgccta gggagttgga
     1921 ccactggcat acaaattgag cgttttctat actcaccttt tcttcaaaac gaattgtcat
     1981 cttttcctca ccatcttatc tatgtttctc cattatacta tttctcccat tttttacgaa
     2041 tagataagta tgattgattt ttattttttt ctcgtcggga gcattctagc ttcctttctt
     2101 ggtttggtca ttgaccgttt tccagagcaa tccattatca gttcagccag tcactgcgat
     2161 tcctgtcaga ctcccttgcg tcccttagat ttgattccga ttctctcaca ggtcttcaat
     2221 cgctttcgct gtcgctactg caaagttcgc tatcctgtct ggtatgccct ctttgaacta
     2281 ggcttaggac tcctctttct gctttactct tgggaattgc tttccttggg gcaagtcgtc
     2341 ctaatcaccg ctggtttgac cttgggtata tacgactttc accatcagga atatccctta
     2401 ctggtctgga tgactttcca cctaatccta atagcttcct ctggctggaa tctggtcatg
     2461 gtctccttcc tcatacttgg aattttggct cattttattg atatccgcat gggtgcaggg
     2521 gatttcctct ttttagcttc ttgtgctctc gtctttagcg taacggagtt actgatcttg
     2581 attcagttcg cttctgcgac gggtatcctg gcctttctcc tgcaaaagaa aaaggaaaga
     2641 cttcctttcg tgcctttcct cttacttgct acttgtttga ttatttttgg taagctacta
     2701 cttgtttgat aaattccaat ttctgccata tgtactccat gaaattattt cacagttaaa
     2761 ttataaatta tttcttttgt acaaagggat gatgttatca aatcgatctg ttcttctatc
     2821 ttcttgatac tgatcaaaaa atttcatttc gactgaaaat atttcgctta taaactgtaa
     2881 acgaatactt tgtttagaca ttatagtcgc tagactgact agatgattac tcaaaacgac
     2941 gtccagaata ctctttactt tgcttggttt tttaacaaaa atttgatcat ccaaaggttc
     3001 aatcattttg taaccttttt gcgcaatttg acgataaaag taagaatgtt gctttggagt
     3061 caataatcct aacttaaaag ctcgatactc taaagcctgt atcgaaacat tcaaatccga
     3121 cttcaataaa atataactat caggattgct gacacgcttg ccaaccctct cttcaaattt
     3181 gactaaaaac tcttcttttg gcaataaaaa acatgatgca aaataatttg cttcttgctc
     3241 caaacgatcg ccatcttcat tcatatcttt atatttatgt aaaagaatat gtcctagctc
     3301 atgagctaaa tcaaaatttc gacgtacaga tgatttattc gttcccaaca caatataagg
     3361 tcttcccaat tttgaccatg cgctataagc atcagcttgg ccattaatta atcgttccac
     3421 gatatagatg cctgaacgtt ctaatttata aagcaaatca tgattatctt ttgaaatacc
     3481 taatttttcc ctggcataaa gagccaattc ctcaatggat tctcccttat gataagattc
     3541 actcactaca ttacttaggt catgaattgt aatattaggt ataattacaa aactttcaaa
     3601 ataatcaatc aaactatcta ccttatgtaa atacatagtt tgaatatcta ttgttttccg
     3661 ggttgctagg tctgcatttc taaaggcaat tacagaagaa tcaaatcgaa tgctctcttc
     3721 ttcctgttca aaataagtta aatcaacatg aaattggttg gccaaatgca ttttggttga
     3781 taatttaggt ttcgtttcgt tggactcaaa ctgccaaatg gcttgttccg ttaaattaat
     3841 tctctgagct aattctgctc tacttaaacc atttaacagc cgtaattctt tcaatacccg
     3901 accattaaac atttacatac tccttactac ttttgacctt cttgtttttc tattcttgga
     3961 ataatttcaa aatcttctgt ttccgataat tctgaaaaat taggaatatc ttgatattta
     4021 gcttcttcga aatggtacga acttgattga atatactcag acaaatcttg aatcaagtgt
     4081 aactgaccag ttcgtgcatc aggcataaca acatctacag atataatatt gttttctgag
     4141 tccgcctcat aagttaaaat cataaatttt tcgatattcg aatttttagt agcttgttca
     4201 atttcttgaa tcatttcatc agaaactaac tccatctgaa ttggaaagga atgactatct
     4261 tcatcatttt tgtaggaaga atgttgatta agataaagtg tattcatctg agcatattca
     4321 aataagtagc cactcttatt tttttgtacc aaaggaaatt ggttcgtaag tcgcttctta
     4381 ccctttataa ttaacaatac tttcccatat ttttctgtgt ttgtttcaaa ttctaaatat
     4441 ccccaagtct gtcctgctaa ttgtaattta tactcaaaca aatctgctga tgcaaatgca
     4501 gtatcaatat gattaggtcg cgtccatgca taaccattcg acactatcat tgtctctctt
     4561 ttttctagac gttcatctac ataatctttt tgccctttca tcaaagtatc tacaattttt
     4621 tgtgcctcaa gcgaatcaaa gagatcctga ttcaacataa ttcttcctcc tccaaatact
     4681 ttttaatgaa ttatatc
//
LOCUS       DBJKQU010000074         4381 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.074, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000074 DBJKQU010000000
VERSION     DBJKQU010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.074"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(170..1585)
                     /locus_tag="ACSUUC_001918"
     CDS             complement(170..1585)
                     /locus_tag="ACSUUC_001918"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHQ8055070.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDITLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1598..3436)
                     /locus_tag="ACSUUC_001919"
     CDS             complement(1598..3436)
                     /locus_tag="ACSUUC_001919"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HHQ8055071.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAASFSALLAGITEPAVYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGIELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3454..4293)
                     /gene="licT"
                     /locus_tag="ACSUUC_001920"
     CDS             complement(3454..4293)
                     /gene="licT"
                     /locus_tag="ACSUUC_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HHQ8055072.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFVALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
BASE COUNT         1463 a          865 c          574 g         1479 t
ORIGIN      
        1 accaatctat cctaagttaa ctatttataa tcggctctct gtaacaaaat taaattaatc
       61 cccctataaa ataaagaggt ttagaatttg atgtcttcca aacctcttta tttcatattt
      121 aatgagatgc tgccttaacc gtgataatat ctaatcatca ataaacaaac tatttgaata
      181 aggattctcc atttgattca atcactcctt tataccaagt aaaggacatt ttcttatatc
      241 gattgaatgt gccatttcca tcatcatttc gatcaacata aatgagaccg taccttttag
      301 aaagttgtgc agtggacata gaaacacagt caatacatcc ccaagacgta tagcccataa
      361 tttcaacacc atcctgtaga gcttcagcaa cttgcaataa atgttctttc atatactgaa
      421 ttctataatc atcttggacg gttaagttat taagttcatc ttttattagt tgatctttag
      481 cacctaatcc attttctact ataaataatg ggatttgata acggtcataa tatctattta
      541 aaattatacg tagtccaatt ggatcaattt gccatcccca ctctgaagac tctaaataag
      601 gatttactaa accaccaata atattccctt ctcctgaatt atactgtgtt ggaagagcag
      661 attgagtcac actcatgtaa tagctaaagg ataaaaaatc tacagtataa ttttttaata
      721 actctgcatc ttcagctgca aactctatgt taatgtcatt ttccttaaaa tatctttttg
      781 cataattcgg ataataacct ctaacatgca catctgaaaa tagataattt agattctcat
      841 actcatgagt cgcccataca tcttttggat ttggagtcat tggataagct ggcatagcta
      901 ataccataca ccccacctta aactctgaat taatctcacg agcaattttt gtaaccaaac
      961 tcgaggcgac taattcatga tgtatagctt gatataattc ttgtttcgaa agattctcct
     1021 taggtatatc tattcctcca ctagtaaacg gtaattccaa aacagagttt acttcgttaa
     1081 atgtaagcca atatttaact ttatctttat acctttctaa aactgttcga gcaaattttt
     1141 cataaaaatg aatcattctc ctatcaatcc atccatgata ttttcttgct aaatataatg
     1201 gagtctcata gtgtgaaaga gttacaagtg gttctatccc gtgagcatgt agttcatcaa
     1261 acaattcatc ataatatttc aacccagctt cgttaggttc ttcctcatct ccttttggaa
     1321 aaattctact ccatgcaata gaagtacgaa aaacattaaa gcccatttca gaaaacaagg
     1381 ttatatcttc cttatattta tgataaaaat caatacctat caattttaag ttatcttctg
     1441 taggattttc tgttgcttct cctaatccac ctttgggtaa cacatcctga actgataagc
     1501 ccttaccatc ttcattatat gctccctcta cttgattagc tgcaacagct ccaccccaaa
     1561 gaaaatcatc tggaaaaatg gtcataactt tcctccatta taatattacc agtaattcct
     1621 tagaatgctc gattgtctga ttattaggta atactaatac atctagaaaa tcattggtat
     1681 tcgttacaat tactggtgta actgtttcgt agcctttagt cttgattaaa ttcaagtcca
     1741 tttcaaaaat caactgattt ttgaaaactc tgtctccttc ttctacatga ctaataaaac
     1801 cttgaccttt tagctcaaca gtatctaatc caatatgaat tagtaactca ataccctcat
     1861 cactcttcaa tccaattgcg tgcttagtcg gaaaaatatt tgtaattttc ccatcaaatg
     1921 gtgcataaac cttaccttca cttgggataa tcgctactcc gtctccaatt agtttatctg
     1981 aaaatgtttt atcctggaca tcgcttaacg gaatgatttc tcctgatata ggagaaaata
     2041 tcattttttt atttgaaact ccagctttaa cttctaaatt gctagaactc tcttcttcat
     2101 cgattccaaa tatataagct aatacaaagg taataacaac cgaaatgacc gccacaatta
     2161 aagcatttac aatatttgat ggcacatcag aataaataaa ttgaggcaac gctatcaaag
     2221 atgggacagc aaatagatac gctttaacac tagtaagacc tgcaaataat cccgctaatc
     2281 caccaccaat catagctgca taaagcggtt ttttatattt taaagtcaca ccatatactg
     2341 caggttcggt aatccctgca agtaaggctg agaaacttgc tgcaaaagca atttgttttg
     2401 tattattatt tttactcttt aatgcaacag ccatcgaagc agccccttga gctaagtttg
     2461 accctaacat tgctggaaga attaatacgt ctggagtagc aatagatgcc gccaaaaaaa
     2521 taggtgcaaa agcccaatgc attccagtca taacaataaa tggcataata gcaccaagaa
     2581 tagctaatgt aagccatcca gctacaccat acatttgccc aactagattt gataatcctt
     2641 caccaacaat tactccaata ggtccgacta caactaaggc aatacagctt gatactaata
     2701 atactagcgt aggttgcaaa aaactcttag taatagctgg tgttaattta gcaattattt
     2761 tttcaatata tttcatcaac caaaccataa taagaattgg aacgactgat gaaccataac
     2821 tagctggtgt cacaggtgca ccaaataaac taagaggatt ccctgattgc accatttgaa
     2881 caaaatttgg atggagaagt acacctgcta cagacatagc taatgtagat gttactttta
     2941 atttttgtga tgcagaataa gctaataaca gcggtaagaa ataatatgga gcatccccaa
     3001 aaaatgtcaa aaaagcaata gtctgagaat ctgattgcaa tataccaagc attggtaaaa
     3061 tgattaccaa gactttcaac atacctcccc ctaacattgc tggaatgatt ggagtcatgg
     3121 aaccagcgat atactcaatg attctttcta aaatattccc tttgtgccct tgaacaactg
     3181 aatcggattc aaaattgcca agtttaacga attctttata ataattagct acatcattac
     3241 caagtataat ttgatattgt ccattctttt tcataatacc tattacacct ggtatcttct
     3301 tcacatcatc atcattgact aaattttcat cttttaattc taatcttaaa cgtgttacac
     3361 aatgggtaac tctattgaca tttttttcac ctccaattac atcgaggatt ttttgtaccg
     3421 tatctttata actcatggta ttctcctatt ctattaatct aaattttttg ttaagcgacg
     3481 aatatgagcc atcaaataaa ctaattcact agaagtcagc aaataattgt actccgtttg
     3541 tataaacatt gccacctgtt caccacattc atattctcta ggatatttat ttttcattaa
     3601 tgctaacaag tcttcatcat catcgtcaca ataagttgta ttttcaacca agcgatgggc
     3661 aaataatttt atatgagtta tgaatctata ataatcaata gaatcttggt taaactcagt
     3721 acaatagaaa tcttgaatga ttttctcaat tcccataatt atttcagtga ttttatacga
     3781 ctcttgaaaa ttattttcta aattagcatt aacaaaatgt agcgctacga atgcagcttc
     3841 gtcaattgga agttcaatac ctaactcttt ttttattatt tgtaaagccc ttttcccaag
     3901 ctcaaattct tctttataat atttcgagat ttcccagcgt aggggattcg aaataataac
     3961 tccttcttta taacgttcta tactcgaaga aatatgatcc gttagattta tatagataat
     4021 ctcatcaaaa ttattaccta atgttatttt acctagatta attatttttt cggtgatgta
     4081 caccaactcc aaaggaacgt taataaacat ctctgtaaaa cgggtcatat tatctctatt
     4141 tttgagaaaa aaacttttct caatatcaat tggatttact ttatctccaa tttttcttcc
     4201 aaaagctatg ccccttccaa aaagaagaat atcgatatct tttttacttt gcgcaattac
     4261 ggcattgtgg tttagtattc gttttatgat cataaaattt cccttttaaa ataaaaggaa
     4321 cctacttaaa aaacatcaag aaacttcttc tgatgtgatt aaataggttc ctgctcactt
     4381 g
//
LOCUS       DBJKQU010000075         4281 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.075, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000075 DBJKQU010000000
VERSION     DBJKQU010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4281
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.075"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..275
                     /locus_tag="ACSUUC_001921"
     CDS             <1..275
                     /locus_tag="ACSUUC_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055073.1"
                     /translation="YLLYKVGFLGIIYDNEALRDLSKQYLNKNISELQDGSFEGGIQD
                     AVASKQIVVINEFIACLNSRCVPSQYDRFFYKDRPYIFSRKSPIKG"
     gene            590..1567
                     /locus_tag="ACSUUC_001922"
     CDS             590..1567
                     /locus_tag="ACSUUC_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055074.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLNKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            1944..2318
                     /locus_tag="ACSUUC_001923"
     CDS             1944..2318
                     /locus_tag="ACSUUC_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HHQ8055075.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            2325..2507
                     /locus_tag="ACSUUC_001924"
     CDS             2325..2507
                     /locus_tag="ACSUUC_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055076.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSITFLAYDFVSEEIKKLIIWINVV
                     FLILIIAMMIYPKLRK"
     gene            2526..3428
                     /locus_tag="ACSUUC_001925"
     CDS             2526..3428
                     /locus_tag="ACSUUC_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055077.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            3484..3837
                     /locus_tag="ACSUUC_001926"
     CDS             3484..3837
                     /locus_tag="ACSUUC_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HHQ8055078.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            3834..>4281
                     /locus_tag="ACSUUC_001927"
     CDS             3834..>4281
                     /locus_tag="ACSUUC_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055079.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDTKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILY"
BASE COUNT         1431 a          556 c          753 g         1541 t
ORIGIN      
        1 attatttact atataaggtt ggatttttgg gaatcattta cgataatgaa gcattaagag
       61 atttgtcaaa acaatattta aacaaaaata tttcggaatt acaagatggt tctttcgagg
      121 gcggtataca agatgctgtt gcctctaaac aaatagtagt tataaatgaa tttatagctt
      181 gtttaaattc cagatgcgtg ccatcccaat atgatagatt tttttataaa gatagacctt
      241 atattttttc cagaaagagt cctattaagg ggtgaaaatt tgttacattt ggattaacaa
      301 gtgtcctagg gattagaaat aactctagta tagctagata tttttgagta actagaaata
      361 tcattaggct acccatatga ttgccagaaa agatggctga tgaatcttat ttatactgtt
      421 gcagtaggca ttgtctagga taaataagct atcttgatgg gggagattgg aataatttta
      481 gtagaaacat taaaggatta tggacaagta gcgcaggatt aggtgatgca atgtgctaag
      541 ttggcttggt gttagcagta gtattattta acaatggaaa gtagactaaa tgaaaaataa
      601 acgttatttt tttgacacaa ttttaataat tttactgctt ataagcacga tattttgtgt
      661 cagcccagta tttataaaat tggacatctt aggaactccc tctcatgcca tcttaacctt
      721 tgtattggcg ataccgttat tctatatttt gtctcaatgc ttacatactt tgctattact
      781 agtttcctca atcttttgta aattaagacc aatttatttt tattttatat ttgtgatcat
      841 tataggagct aggaaatact atcgaattct ctttcaccaa ctaatgggat ttagtccagg
      901 aatagcagtg ttttataagg agagtcaaac aactaagaat ctgtttaaat tttactactt
      961 cttgtacttt acaacactaa tttcatacta ttttttcttt acttttgtgt atgacaaacc
     1021 gttgcttttg cctcttattc cattttctat tatcatagca ttagtacaaa aactttatag
     1081 aattgagaat caacaattat ttctgttaaa atcaaaggta ctaacaatac tggaatctaa
     1141 gagggattgt gagtttaatc ttcaggatta tcatgaaatt tggaaattgc aatcaaaatc
     1201 tgagttgcca tgcgtggctt tatcttatat cagtttgatc aagccatatc tttcagagag
     1261 cgtgcgtgaa caaattgatt tattagaagt taagcgattt aaaaaaataa atcatccaat
     1321 atcactttat ggtatgttgg atgttataaa attaaatcta tatttacggc attataatga
     1381 aaaaaataaa tatgaatcaa tgttaaataa aattttagag gtaagaccag actttgtttt
     1441 aatcgagcag aatattgatg atagtttaaa tagctcgcaa ccattatctt tatctttagc
     1501 catttcagaa atccaacttt tgcttgaagt gtatatgggg atcaaacatg tttcaattag
     1561 gagataaaac cagaataata tttgccatta taggggcaag ttgcatatta gtcagtatgt
     1621 atcttattcc acttattaaa actgagaata aattttggga aatactttta tttatattag
     1681 gtgtattgct aattggaatt gcgttattaa gtcaaaaaaa ataaattttg aaatagtatt
     1741 agtgagttcg caatcattta ttgctagtgg tttagaactg ttaagtttca aacaataatt
     1801 gattttaaac cttaggtaac ctataaaaac aaataaggta gagaaaggat atcttatcta
     1861 ggtagctaag tgataaaaac acagtcgtct atcacttgtt aggaaactat cctaactatg
     1921 cttaataaaa aaggagaaaa taaatggaac tcgtattacc aaataattat gttgttcttg
     1981 agcaagaaga gatgatgtat cttgatgggg gattttctat tccgagatgg cctgttgcaa
     2041 cagccattaa tatagctttt aatggtgttt taggtggagg agcaatcagt ctagttagaa
     2101 attatattcg taattatggt ttgcggcgag ttacaagcgc aattgctgga gcagctgcaa
     2161 gatatgttgg ggtacgagtt gcaaatagag tggcaggatt tgcactgtct gctattaatg
     2221 gatttgcagc ttggatgtca attggcgatg ctattacaac aatctgggcc aataatgatg
     2281 taaataggag agacccaaat ttaaacgcct tgtggtaact agatatgggt attaaaatgg
     2341 aaaaaatttt tgttattatt ttttttgtat gtctatttat atcatccata acttttttag
     2401 cctatgattt tgttagcgaa gaaataaaaa agttgattat ttggattaat gtcgtttttt
     2461 tgattttaat catagcaatg atgatttatc caaaattaag aaaatgataa ggacactgta
     2521 aaattatgat acgtaaacta attgttttct tactaatgct ccctcttttt gtcttgtggc
     2581 tagagttgca tgtcctagtg aataacttac tattgaatct agaatctccc cttgattttg
     2641 tgattagtat gagtcttgct ttctgtagtt tgattttatc aaaaatagtt ttagacatac
     2701 tatacgcatt gaaagattta tacaagaaag aaggtcttat taagattttt ccctttattt
     2761 ttataagaag gaaaaaagtg aatgtgagat tctcgcccta tttttcattc catcgtaaaa
     2821 gtttgtcgcc tgatgattta agatctagga ttatatggag ttttattctt gaaattgcta
     2881 ttatcctagt atttatttta aaaattcctt ttgcaatcat catgcttact acaatatttt
     2941 tctggactat aatggatatc aatcatctcg tttttaataa gacggaattt ctttttaatc
     3001 aaaacaaatg gcaaaaagaa gattcatttg aaagtaattt gcataagata ttgatggaca
     3061 aaatacaaaa atcagaatta agctattctg acttaatgtc ccttcttctc tatgatgcga
     3121 tgaaccaatc caccttttta acggatagtg aactttttga ggatattttg aaaaaaatcg
     3181 aagattctca taacaccctt ctgtgtacag gtcttgtcga gttactgctg tatgagattt
     3241 ctattagtaa caataacaac tggcaagaaa aggttgataa aattagaata cagctcatca
     3301 gaataaatca attagatttt ttctattata caagttggtt aaggcaaaat tttgatttct
     3361 gtatgaatag agagtatcat aaaatgaaat ctcggaaatt attactgagt aataaaaaga
     3421 tagtttaagt tcgtcctatt tgtaaaacaa atgaaacaat ttcaactaag gaggagaaaa
     3481 caaatggaac ttgtattacc aaataattat gttgtgattg atgaagaagt aatgatgtat
     3541 cttgatgggg gagcttattt aagcaagcgt gcttgtcaag gaatttgcgc agctttagct
     3601 atgagttcag gaacttttat agcattagct ggagctgcag ttttaaccaa aaaactaata
     3661 aactatatta aggttggagg tcttggaggc tggcttattg gtgcagcagc aggtgtattg
     3721 gctacagcag cagggaaaat agcttactgt attggatatg gtgttcttaa tagaggttgt
     3781 gatattaacg ggaaccctta tccttgggat ggattcatat ctgcaacagt aagatgagta
     3841 atgtagataa gattcgaaaa atacacatca tcgtgtgttg ggtgtatata tttttatcat
     3901 tcagggcgat tataaatgat acggagtatt ttttgcttat ttttttagct tttatctact
     3961 caatagtatc actacctcta tattctgtga aaaataaaat agtatctatc tgtctagcca
     4021 taaattcgat tctgttaatg agttttccca ttttaatcaa taagtttttc ccagaaagtt
     4081 ttttgactta taccgtatta ataagtgttt ttattacaga gttgataatt tttcatttaa
     4141 ttgggaaaga ttttgatact aaattgacta acgaatataa gaaaattagt cagttcagaa
     4201 gcaaggtgtc tcaatctcct tggataaaat atttagagat ttctagtttt atattaacta
     4261 tatttccatc cattctttat g
//
LOCUS       DBJKQU010000076         4262 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.076, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000076 DBJKQU010000000
VERSION     DBJKQU010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.076"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            67..312
                     /locus_tag="ACSUUC_001928"
     CDS             67..312
                     /locus_tag="ACSUUC_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055080.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFTKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
     gene            713..1705
                     /locus_tag="ACSUUC_001929"
     CDS             713..1705
                     /locus_tag="ACSUUC_001929"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8055081.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1707..2525
                     /locus_tag="ACSUUC_001930"
     CDS             1707..2525
                     /locus_tag="ACSUUC_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8055082.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2527..3312
                     /locus_tag="ACSUUC_001931"
     CDS             2527..3312
                     /locus_tag="ACSUUC_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHQ8055083.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3351..3629
                     /locus_tag="ACSUUC_001932"
                     /pseudo
     CDS             3351..3629
                     /locus_tag="ACSUUC_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
     gene            3566..3811
                     /locus_tag="ACSUUC_001933"
     CDS             3566..3811
                     /locus_tag="ACSUUC_001933"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHQ8055084.1"
                     /translation="MSRRKKAYQGRKIGSQLLATLESEAHKKVGYLQVKTVAEGSNKD
                     YDRTNDFYRGLGFKKLEIFLQLWNPQNPCQILIKKLE"
BASE COUNT         1190 a          734 c          912 g         1426 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattaatatc tgattataaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt
      121 aagtgttatt ttacaaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt
      241 tataatgaga ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt
      301 tggtttaggt agtcgatgcg tgagttgata attctcaggg tatggacttc tttttcatga
      361 atgaggtaaa agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag
      421 agggagtatc cgattttatg atcaaagtta ataccgccct ctggtgagaa gatgagtagg
      481 ttggtaattt aaactattaa acagaatttt tgattaaaag tattatttta tgagagaaat
      541 cctaatttca caatccatag gcaaacgctt gcattctgtt ttttattgga ctataatagg
      601 ttggtataaa gccttctgta gtaataaaat gtagaaggtg tagaaagtaa ggatttagaa
      661 tatttgtagt taaaaataca atgttgctat tccttatgat agggagatag atatggcaat
      721 gatagaagtg gaacatcttc agaaaaattt tgtgaagact gttaaggaac cgggcttgaa
      781 gggggctttg cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt
      841 gacctttgag gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa
      901 gtcgacaacc attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat
      961 taacggcaag attccccaga acaatcggca agattatgtc aaagatattg gcgtagtctt
     1021 tggacaacgc acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa
     1081 agagatttat gatgtgccag actcgctctt tcataagcgt atggactttt tgaatgaagt
     1141 cttggatttg aaggacttta tcaaggatcc cgtgcgaact ctttcactgg gacaacggat
     1201 gcgggcggat attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc
     1261 gaccattggt ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagatcaa
     1321 tcaagaggaa gaaactacca ttcttttgac cactcatgat ttgagtgata ttgagcaact
     1381 ttgtgatcgg attttcatga ttgacaaggg gcaagagatt tttgatggaa cggtgagcca
     1441 actcaaggag acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag
     1501 tcatctcgtc tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag
     1561 cctcaacatt gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct
     1621 gtctgatttt gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg
     1681 tcgcttctac cgaaaggagc tctaggatga tcaaattgtg gagacgttat aaacccttta
     1741 tcaatgcagg ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg
     1801 gcgatgtcat gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc
     1861 aagagtcttt gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt
     1921 ttgtgaccaa tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg
     1981 atggctccat tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca
     2041 ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg ccttccattt ttaagtgtca
     2101 ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtcc
     2161 tttatctttt tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg
     2221 gattttcagc ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag
     2281 tggcttttat gtcggggagt ttgattccct tggcattctt tccaaaggtt gtttcagata
     2341 ttctctcctt tttgcctttt tcatccttga tttatactcc agttatgatc attgttggaa
     2401 aatacgatgc cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga
     2461 tggtgggatt gtctcagttg atttggaaac gggtccagtc ctttatcacc attcaaggag
     2521 gttagtatga aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa
     2581 atcatggaat ataaggtgga ttttgtggtt ggtgttttgg gagtctttct ggctcaaggc
     2641 ttgaatctct tgtttctcaa tgtcatcttt caacatattc cattcctaga aggctggacc
     2701 tttcaagaga tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc
     2761 ttttttgaca atctctgggc actagggcaa cgcctagtcc gaaaagggga gtttgacaag
     2821 tatctgactc gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat
     2881 gccttgggtg aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt
     2941 tggactcttc caaaattcct gcttttccta gtttgtattc cttttgcgac cttgatttat
     3001 acttctctta aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg
     3061 atttacatct tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct
     3121 cttcttcgtt ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct
     3181 agctatttct tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat gttgatttct
     3241 ctggttttct ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt
     3301 gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa ggaacttatg atgtttgtaa
     3361 ttgaagaagt caaggatgaa aatcaaaaaa aggcagttgt cgctgaggtt ttgaaggatt
     3421 tgccagaatg gtttggaatc ccagaaagca cataagccta tataaaagga accacgacac
     3481 tgcaagtttg gaccgcctat caggagagtg atttgactgg atttgtaagc ttatcctatt
     3541 cgagtgaaga ttgtgcagag attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa
     3601 aattgggagc caattgcttg ctactttaga gagtgaagct cataaaaaag ttggttatct
     3661 gcaggtcaaa acagtggcag aaggttctaa taaagattat gatcgaacaa atgactttta
     3721 tcgaggtctt ggctttaaaa agttagagat ttttcttcaa ctatggaatc cgcaaaatcc
     3781 ttgtcagatt ttgattaaaa agcttgaata atattacttg acatctattc tcagagtgct
     3841 atactgtaag tgtaatcgcc gatttagctt agttggtaga gcaaggcact cgtaaagcct
     3901 aggttatagg tagataaacg actgaggatt tgaaaaaata gataggtaga agataaccgt
     3961 taagccttac tcttagcggt tatttatatt gtttaatagc gctaatattt tatcaattat
     4021 gcctgttttc gtgtttctgg tagttgttca agtttattgc taatattttt gatggtatga
     4081 atgtgcttat aatgtatccc ggttaacgaa agttttggac ttatactctt cgaaaatctc
     4141 ttcaaaccac gtcaacgtcg ccttgccgtg cgtatggtta ctgacttcgt cagttctatc
     4201 cacaacctca aaacagtgtt ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca
     4261 gt
//
LOCUS       DBJKQU010000077         4236 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.077, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000077 DBJKQU010000000
VERSION     DBJKQU010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4236
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.077"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..978
                     /locus_tag="ACSUUC_001934"
     CDS             <1..978
                     /locus_tag="ACSUUC_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HHQ8055085.1"
                     /translation="FSACSSNSVKNEENTSKEHAPDKIVLDHAFGQTILDKKPERVAT
                     IAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKELNGKANLFDDLDGLNF
                     EAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQTLWRDMIKIDSKALGME
                     KEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAADTSKFWIYTSKDPRANY
                     LTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITYGDDKTLEALQKDPLLG
                     KINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLGNACKNAK"
     gene            968..1975
                     /locus_tag="ACSUUC_001935"
     CDS             968..1975
                     /locus_tag="ACSUUC_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HHQ8055086.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            1975..2982
                     /locus_tag="ACSUUC_001936"
     CDS             1975..2982
                     /locus_tag="ACSUUC_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HHQ8055087.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFAKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            2982..3776
                     /locus_tag="ACSUUC_001937"
     CDS             2982..3776
                     /locus_tag="ACSUUC_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHQ8055088.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
BASE COUNT         1534 a          628 c          722 g         1352 t
ORIGIN      
        1 tttagcgctt gttcttctaa ttctgttaaa aatgaagaaa atacttctaa agagcatgcg
       61 cctgataaaa tagttttaga tcatgctttc ggtcaaacta tattagataa aaaacctgaa
      121 agagttgcaa ctattgcttg gggaaatcat gatgtagcat tagctttagg aatagttcct
      181 gttggatttt caaaagcaaa ttacggtgta agtgctgata aaggagtttt accatggaca
      241 gaagaaaaaa tcaaagaact aaatggtaaa gctaacctat ttgacgattt ggatggactt
      301 aactttgaag caatatcaaa ttctaaacca gatgttatct tagcaggtta ttctggtata
      361 actaaagaag attatgacac tctatcaaaa attgctcctg tagcagcata caaatctaaa
      421 ccttggcaaa ctttatggag agatatgatt aaaattgatt caaaagcctt aggtatggaa
      481 aaagaaggtg atgagttaat caaaaatact gaagctcgta tatccaaaga attagaaaaa
      541 catccagaaa tcaaaggaaa aatcaaagga aaaaaagtat tatttactat gattaatgct
      601 gcagatacat caaaattctg gatttatact agcaaagatc caagagcaaa ttatttaaca
      661 gatttaggtc tagttttccc tgaatcatta aaagaatttg agagtgaaga tagttttgca
      721 aaggaaattt ctgcagaaga agcaaataag ataaatgatg ctgatgtaat cataacttat
      781 ggtgatgata aaactcttga agctttacaa aaagatcctc ttttaggtaa aataaatgca
      841 attaaaaatg gtgccgttgc tgtaattcca gataatacac cgttagcagc ctcatgcact
      901 ccaacaccac tttcaataaa ctatactatt gaagaatacc taaatctttt aggaaatgca
      961 tgcaaaaatg cgaaataaaa aacaaataaa cctaggcata atttttgtaa tctgcctagg
     1021 tcttcttatt acaatatttt tgtcattaaa gcttggaaca aaagaaatta atatcagaga
     1081 ttttttagca gcttttggaa tgggtaatac aaatgatgat tttattaaat caattatata
     1141 taaaagaata cctagaacta tttttgcaat tttagcaggt tctagtcttg ccataagcgg
     1201 tgtattgatg caatcagtta ctagaaaccc aatagctgat ccaggtatac tcggtataaa
     1261 cacaggagca agtcttagtg tagtaattgg tctttctttt ttaggaattt catcaagcat
     1321 aagccatata agttttgcaa tcattggtgg cttagtaagt gcaatttttg tatacgcgat
     1381 tgctgtaagc ggaaaagcag gccttacccc tataaaactt gccttatcag gaacttgtgt
     1441 tagtatggct ttaagcagtt ttgtaagttt tttaatttta ccgaataata acgtcttaga
     1501 caaatttaga ttttggcaaa taggtagcct tggagcagct acattatctt ctatatctac
     1561 actactacct tttataattt taggtcactt gatagctata tttatttcat cagatttaaa
     1621 cgctttagct atgggtgatg aaatggctgt tggtcttgga gttaatgtta ataggataag
     1681 atcacttgca ataattgcaa gtgtgctttt atgttcaagt attactgcaa ttggtggacc
     1741 tattggcttc gtaggtctta tagttcctca cttttgtggc ttatttataa gcaaagatat
     1801 acgcacaatg accatttctt catcttttat aggtgcagag ctcttgctta tatgtgatat
     1861 aatcggccgt atgttaggta aaccaggtga aattgaagta gggataatta ctgcaataat
     1921 cgggggtcca gtacttattt atgtaactat gaaaaataga ggggttaata actaatgcaa
     1981 aatttaatta taggtattca aaaaagaaaa aatagaataa cactattttc ctcactattt
     2041 ttattaataa taatcagtct atcatttttc attttactta tcggagatga aagttattct
     2101 ttttcaactt tgattaaagt cttaaatagt gaaactgttc ctggagctag tttttcgatt
     2161 atggaaatta gattaccaaa attattagca ggaattatag ctggctggtc ttttggattg
     2221 gcaggattta tctttcaaac tatgttaaga aatcctcttg caagtcctga tataatcggt
     2281 gtcacaagtt cttcatctat tgcagcggtc ttttgcatat tggtattaaa aacaaatagt
     2341 ttaactactg gaattatttc aataacttgt ggactaacat catctttaat attattttta
     2401 ctagctaaaa aagatggttt ttcagcagca agactgataa tattaggtat tggttttcaa
     2461 gctgtcacaa gagcaggcac ctcattttta ttgttgaaag tagcaagata tgaattacaa
     2521 gaagttatga gatggctcag tggctcttta tcttttgcaa agttagatga catacctctt
     2581 gttctaatag taagtattat tgctactata ttagttttat tttttaataa aagactagaa
     2641 attattgaac ttggtgaaga aatagcaatc ggacttggag caaatcccga gctttcaagg
     2701 cttgttttaa ttttttgcgc tgtatcttta actgcttttt ctacttcaat tacaggacca
     2761 atagcttgta tatctttttt agctggtccc atagccttaa atattggcaa gaaaagaagc
     2821 ccaatattag ctggattggt tggaatttta ctagttttgt tatcagacat attctctcaa
     2881 aatattttac cagctagata tccagtaggt gttgtaactg gcttgttagg ttcaccatac
     2941 ttaatatact tactaataaa aatgaacagg aggaatatat aatgaaaggt ctgtggtcaa
     3001 ataatcttac ctgcggttat gatgaaaaaa taatcttgga aaatataaat ataaaaatac
     3061 ctgaagaaaa aatatcagtt attattgggt caaatggttg tgggaaatca acactcatta
     3121 aaaccttgtc tcgacttata aagccattag agggagaagt attgcttgat aataaatcaa
     3181 ttaattctta taaagaaaaa gatttagcaa aacacatagc tatattacct caatctccaa
     3241 taatccctga atcaataaca gtagctgatc ttgtaagccg tggtcgtttc ccctacagaa
     3301 agccttttaa gagtcttgga aaagatgacc ttgaaataat aaacagatca atggttaagg
     3361 ccaatgttga agatctagca aataacctag ttgaagaact ttctgggggt caaaggcaaa
     3421 gagtatggat agctctagcc ctagcccaag atacaagtat cctactttta gatgagccaa
     3481 ctacttactt ggatatctca tatcaaatag aactattaga cctcttgact gatctaaacc
     3541 aaaaatataa gacaaccatt tgcatgattt tgcacgatat aaatctaaca gcaagatacg
     3601 ctgattacct atttgcaatt aaagaaggta aacttgttgc agagggaaag cctgaagata
     3661 tactaaatga taaactagtt aaagatatct ttaatcttga agcaaaaatt atacgtgacc
     3721 ctatttccaa ttcgcctcta atgattccta ttggcaagca ccatgttagc tcttaataat
     3781 tgaatatcgg aattcattta aaagtcgcaa attttgaact gaccctcaaa agttaggcca
     3841 aaaaactaac taaaggaggt cagtttttta atggcaaata cagcacagaa tttaagataa
     3901 aattagtaaa agaatatcat gaatgaaaaa taggatatag ataataacag caatattaaa
     3961 aagatcagga ctgataataa acaaaaagaa agtacaacga ctagttcaaa agctaaaact
     4021 tcaagtaaaa agttattcaa gaaaatctag aaaatactca tcctacaaag gacaggtagg
     4081 aaaaatatca gacaacaaaa taaaaagaaa tatttattac cgaaaaaaag gggaaatcga
     4141 gtcaagtacc aacaggctca tctattccaa aaagatattt actcgatgga aaaactccta
     4201 gaattagtgc tacaaatatt gacaatggta tcttag
//
LOCUS       DBJKQU010000078         3969 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.078, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000078 DBJKQU010000000
VERSION     DBJKQU010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3969
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.078"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            84..881
                     /locus_tag="ACSUUC_001938"
     CDS             84..881
                     /locus_tag="ACSUUC_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HHQ8055089.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSLLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1029..2288
                     /locus_tag="ACSUUC_001939"
                     /pseudo
     CDS             1029..2288
                     /locus_tag="ACSUUC_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            2384..3658
                     /locus_tag="ACSUUC_001940"
     CDS             2384..3658
                     /locus_tag="ACSUUC_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HHQ8055090.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3670..>3969
                     /locus_tag="ACSUUC_001941"
     CDS             3670..>3969
                     /locus_tag="ACSUUC_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HHQ8055091.1"
                     /translation="MEDDLNYENLMDDVTEAIKKFNLVIFIGAGVSIAQGYPNWNNYI
                     EHLIKYWQGQVLSVSGEKRLGREHHVVFDLISKSSISNKRKVDLVNYELKKVFGED"
BASE COUNT         1231 a          706 c          864 g         1168 t
ORIGIN      
        1 acttttatga aatatagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaaagat ttaggagttt attatggttt cttcagaatt tatctcaaag attgaatttg
      121 cttgcaataa gaaagaaagt ctttatagtc aaagcaaatt taagtatgcg attcgttcga
      181 tgttcgcagg tgcattttta accttcagta ctgctgcagg tgcagttggg gctgacttga
      241 ttaataaaat tgcaccaggt agcggacgct tcctctttcc attcgttttt gcttggggct
      301 tggcctacat tgtttttttg aatgccgagt tggtcacttc aaacatgatg ttcttgactg
      361 ctggtagttt attaaaaaaa atctcttgga gaaaaacagc tgagatttta ctatactgta
      421 ccttgttcaa ccttatcgga gccttgatag cagggtgggg ctttgctcat tcggcagcct
      481 atgcgaatct gacacacgat agtttcatct caggggttgt agagatgaag ttaggccgct
      541 caaatgaatt ggtcttgctt gaggcgattt tggcaaatat tttcgtaaac attgccattc
      601 tttcatttat tttggtcaaa gatggtggtg ccaaactttg gcttgtgttg tcagctattt
      661 acatgtttgt attcttaaca aacgagcaca ttgcggcgaa ctttgcttct ttcgcgattg
      721 tgaaattcag tgttgctgcg gattcaattg ccaacttcgg tgttggaaat atgcttcgcc
      781 actggggtgt gactttcatc ggaaacttta tcggaggagg cctcttgatg ggtcttccat
      841 atgccttcct caataaaaac gaagatactt atgtagatta agaaaatgag cacgattgag
      901 tcgtgctttt ttcattttca aaataagata atagctattt cttatatcaa aatatagaaa
      961 actgatattt gtaaactata actcaaggtg ctacaatatc cttaataaaa taatatggag
     1021 gtcaccttat gactcgtgat tttaaatttg aaactctaca actacatgct ggtcaagttg
     1081 tgactccagc tactaagtct cgtgcagtgc cgatttatca aacaacatct tttgtttttg
     1141 atgacacgta ggaaggtgct gatctgtttg ccttgaggaa accagggaac atttatactc
     1201 gtatcaccaa tcctacaaca gctgcccttg aaggtggtgt tgaagcgcta gcaacagcat
     1261 caggtatgac tgcagtgact tatacgattt tggcgcttgc ccatgctggt gagcatgtag
     1321 tggctgcttc gactatttac ggtggaacct tcaatctttt gaaagaaccc cttcctcgtt
     1381 atggtatcac aacaaccttt gtcgatgttg ataatttgga ggaagtagaa gcagctatca
     1441 aagacaatac caagcttgtc ttgattgaaa ccttggttaa ccccttgatt aatattccag
     1501 acctggaaaa actggcagag attgctcata aacatcaaat cccacttgtg tcagacaata
     1561 cttttgcaac accttatttg attaacgtct tctctcatgg cgttgacatt gccattcact
     1621 ctgcgactaa gtttatcggt gggcatggta caactattgg aggaataatt gtcgatagtg
     1681 gtcgttttga ctggacggct tcagggaaat tccctcaatt tgttgacgag agtccaagct
     1741 gccacaattt gagctatact catgatgtgg gtgcagcagc ctttattata gctgttcgag
     1801 ttcaattgct tcgtgataca ggtgcagcct tgtcaccatt caatgctttc ctcttgctac
     1861 aaagacttga aaccctttca cttcgtgtgg aacgccatgt acaaaatgct gagacaattg
     1921 ttgattttct tgtcaaccat cctaaggtag aaaaggtaaa ttatccaaaa cttgcagata
     1981 gtccttatta tgccttggct gagaaatact tgccaaaagg tgtcggttca atctttacct
     2041 tccacgtcaa aggtgacgag gaggaagcac gcaaggtcat tgataattta gaaatctttt
     2101 ctgaccttgc aaacgcggca gatgctaaat cgcttgttgt ccatccagca acaatcactc
     2161 acggtcaatt gtcagaaaaa gacctagaag cagcaggtgt cacaccaaat caaatccact
     2221 tgtctatcgg tcttgaaaat gtagaagatt tgattgaaga cttacgcttg gccttggaaa
     2281 aaatttaaag taaaagaaga taaacagtgg gttttgactc actgtttttg attttccctc
     2341 aggcatgata taatggttac agaagtctag aaagaggaat gtaatgaacg aaatcaaatg
     2401 tcccaactgt ggggaagtct ttacagtaaa tgaaagccag tatgctgaac ttttgtccca
     2461 agtgagaacg gcagagtttg ataaggaact acacgatagg atgaggcagg aactggcctt
     2521 ggctgagcaa aaggctatga atgagcaaca gactaaactg gctcagaagg atcaagaaat
     2581 tgcgcaattg cagagtcaaa tccaaaactt tgatacagaa aaagaattgg ccaagaaaga
     2641 agttgaacag acaagccatc aggccttatt ggctaaggac aaggaagtac aggccttgga
     2701 aaaccagttg gcgaccttgc gtttggagca tgaaaatcaa ttgcaaaaga ccctttctga
     2761 cctagaaaaa gaacgcaatc aggtcaaaaa tcagctccta ctgcaagaaa aggaaaatga
     2821 gttgtctttg gcttctgtta agcaaaacta cgaagcccag ctcaaagcag ccagtgaaca
     2881 agtcgagttt tataagaatt ttaaggctca acaatctaca aaagcgattg gggaaagcct
     2941 agaacagtat gcagagagtg agtttaacaa ggttcgtagt ttcgcctttc caaatgctta
     3001 ctttgagaag gataacaagg tctcttcgcg tgggtctaaa ggggacttta tcttccgtga
     3061 gtgtgatgaa aatggagttg aaatcatttc tatcatgttt gagatgaaaa acgaagcgga
     3121 cggaacagag aagaagcaca agaatgcaga tttttacaag gaattggaca aggaccgtcg
     3181 ggagaagaac tgtgagtatg ccgttttggt gaccatgctt gaggctgata atgactactt
     3241 taacacaggg attgttgacg tcagtcacga gtatgaaaaa atgtatgttg ttcgtcctca
     3301 attctttatc caattgattg gtctcttacg taatgcggcg ctaaattccc taaaatacaa
     3361 gcaggagttg gccttggttc gcgagcaaaa tattgacatt acgcattttg aggaagactt
     3421 ggatgccttt aagctagctt ttgctaagaa ctataattca gcttcgacta actttggaaa
     3481 agctattgat gaaatcgaca aggccatcaa acgcatggaa gaggttaaga aattcctgac
     3541 tacatctgaa aaccaactcc gtctagctaa caacaaattg gaagatgtct ctgttaaaaa
     3601 attgacccgg aaaaatccaa caatgaaagc gaagttcgaa gcattgaagg gggagtgagg
     3661 aaataagtta tggaagatga tcttaattat gaaaatttga tggatgatgt aaccgaggct
     3721 ataaaaaagt ttaacttagt aatttttatt ggcgcaggag tttcaattgc tcaaggttat
     3781 cctaattgga acaattatat tgaacatctt attaagtatt ggcaaggaca agttttatcg
     3841 gtaagtggtg aaaaaaggct tggaagagaa catcacgtag tttttgattt aattagcaaa
     3901 tctagtatta gtaataaacg taaagtggat cttgtaaact atgaattaaa aaaagttttt
     3961 ggtgaagat
//
LOCUS       DBJKQU010000079         3878 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.079, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000079 DBJKQU010000000
VERSION     DBJKQU010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3878
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.079"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..418
                     /locus_tag="ACSUUC_001942"
     CDS             <1..418
                     /locus_tag="ACSUUC_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HHQ8055092.1"
                     /translation="KNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEKVTDPSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
     gene            628..3747
                     /gene="phtE"
                     /locus_tag="ACSUUC_001943"
     CDS             628..3747
                     /gene="phtE"
                     /locus_tag="ACSUUC_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HHQ8055093.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1455 a          633 c          755 g         1035 t
ORIGIN      
        1 taaaaataag gcagaccaag atagtaaacc tgatgaagat aagggacatg atgaagtaag
       61 tgagccaact caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc
      121 agataatctt tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac
      181 tacagatgag gctgaaattc ctcaagtaga gcattctgtt attaacgcta agatagcaga
      241 tgcggaggcc ttgctagaaa aagtaacaga tcctagtatt agacaaaatg ctatggagac
      301 attgactggt ctaaaaagta gtcttcttct cggaacgaaa gataataaca ctatttcagc
      361 agaagtagat agtctcttgg ctttgttaaa aaaaagtcaa ccggctccta tacagtagta
      421 aaatgaatgg agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa
      481 aaacgtaaca gaaacttgac aaaagtaatt ttaaatagta aactatttac tggttaatta
      541 aatggttaaa taaccggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaac
      601 ttcatcattt attgaaatga gggatttatg aaattcagta aaaaatatat agcagctgga
      661 tcagctgtta tcgtatcctt gagtctatgt gcctatgcac taaaccagca tcgttcgcag
      721 gaaaataagg acaataatcg tgtctcttat gtggatggca gccagtcaag tcagaaaagt
      781 gaaaacttga caccagacca ggttagccag aaagaaggaa ttcaggccga gcaaattgta
      841 atcaaaatta cagatcaggg ctatgtaacg tcacacggtg accactatca ttactataat
      901 gggaaagttc cttatgatgc cctctttagt gaagaactct tgatgaagga tccaaactat
      961 caacttaaag acgctgatat tgtcaatgaa gtcaagggtg gttatatcat caaggtcgat
     1021 ggaaaatatt atgtctacct gaaagatgca gctcatgctg ataatgttcg aactaaagat
     1081 gaaatcaatc gtcaaaaaca agaacatgtc aaagataatg agaaggttaa ctctaatgtt
     1141 gctgtagcaa ggtctcaggg acgatatacg acaaatgatg gttatgtctt taatccagct
     1201 gatattatcg aagatacggg taatgcttat atcgttcctc atggaggtca ctatcactac
     1261 attcccaaaa gcgatttatc tgctagtgaa ttagcagcag ctaaagcaca tctggctgga
     1321 aaaaatatgc aaccgagtca gttaagctat tcttcaacag ctagtgacaa taacacgcaa
     1381 tctgtagcaa aaggatcaac tagcaagcca gcaaataaat ctgaaaatct ccagagtctt
     1441 ttgaaggaac tctatgattc acctagcgcc caacgttaca gtgaatcaga tggcctggtc
     1501 tttgaccctg ctaagattat cagtcgtaca ccaaatggag ttgcgattcc gcatggcgac
     1561 cattaccact ttattcctta cagcaagctt tctgccttag aagaaaagat tgccagaatg
     1621 gtgcctatca gtggaactgg ttctacagtt tctacaaatg caaaacctaa tgaagtagtg
     1681 tctagtctag gcagtctttc aagcaatcct tcttctttaa cgacaagtaa ggagctctct
     1741 tcagcatctg atggttatat ttttaatcca aaagatatcg ttgaagaaac ggctacagct
     1801 tatattgtaa gacatggtga tcatttccat tacattccaa aatcaaatca aattgggcaa
     1861 ccgactcttc caaacaatag tctagcaaca ccttctccat ctcttccaat caatccagga
     1921 acttcacatg agaaacatga agaagatgga tacggatttg atgctaatcg tattatcgct
     1981 gaagatgaat caggttttgt catgagtcac ggagaccaca atcattattt cttcaagaag
     2041 gacttgacag aagagcaaat taaggctgcg caaaaacatt tagaggaagt taaaactagt
     2101 cataatggat tagattcttt gtcatctcat gaacaggatt atccaagtaa tgccaaagaa
     2161 atgaaagatt tagataaaaa aatcgaagaa aaaattgctg gcattatgaa acaatatggt
     2221 gtcaaacgtg aaagtattgt cgtgaataaa gaaaaaaatg cgattattta tccgcatgga
     2281 gatcaccatc atgcagatcc gattgatgaa cataaaccgg ttggaattgg tcattctcac
     2341 agtaactatg aactgtttaa acccgaagaa ggagttgcta aaaaagaagg gaataaagtt
     2401 tatactggag aagaattaac gaatgttgtt aatttgttaa aaaatagtac gtttaataat
     2461 caaaacttta ctctagccaa tggtcaaaaa cgcgtttctt ttagttttcc gcctgaattg
     2521 gagaaaaaat taggtatcaa tatgctagta aaattaataa caccagatgg aaaagtattg
     2581 gagaaagtat ctggtaaagt atttggagaa ggagtaggga atattgcaaa ctttgaatta
     2641 gatcaacctt atttaccagg acaaacattt aagtatacta tcgcttcaaa agattatcca
     2701 gaagtaagtt atgatggtac atttacagtt ccaacctctt tagcttacaa aatggccagt
     2761 caaacgattt tctatccttt ccatgcaggg gatacttatt taagagtgaa ccctcaattt
     2821 gcagtgccta aaggaactga tgctttagtc agagtgtttg atgaatttca tggaaatgct
     2881 tatttagaaa ataactataa agttggtgaa atcaaattac cgattccgaa attaaaccaa
     2941 ggaacaacca gaacggccgg aaataaaatt cctgtaacct tcatggcaaa tgcttatttg
     3001 gacaatcaat cgacttatat tgtggaagta cctatcttgg aaaaagaaaa tcaaactgat
     3061 aaaccaagta ttctaccaca atttaaaagg aataaagcac aagaaaactc aaaacttgat
     3121 gaaaaggtag aagaaccaaa gactagtgag aaggtagaaa aagaaaaact ttctgaaact
     3181 gggaatagta ctagtaattc aacgttagaa gaagttccta cagtggatcc tgtacaagaa
     3241 aaagtagcaa aatttgctga aagttatggg atgaagctag aaaatgtctt gtttaatatg
     3301 gacggaacaa ttgaattata tttaccatcg ggagaagtca ttaaaaagaa tatggcagat
     3361 tttacaggag aagcacctca aggaaatggt gaaaataaac catctgaaaa tggaaaagta
     3421 tctactggaa cagttgagaa ccaaccaaca gaaaataaac cagcagattc tttaccagag
     3481 gcaccaaacg aaaaacctgt aaaaccagaa aactcaacgg ataatggaat gttgaatcca
     3541 gaagggaatg tggggagtga ccctatgtta gatccagcat tagaggaagc tccagcagta
     3601 gatcctgtac aagaaaaatt agaaaaattt acagctagtt acggattagg cttagatagt
     3661 gttatattca atatggatgg aacgattgaa ttaagattgc caagtggaga agtgataaaa
     3721 aagaatttat ctgatctcat agcgtaagga atagcagtag aaaaagtctg aatcaaaaat
     3781 gaagttctct caaaagttag aaataaaact ctgactttgg gagaatttca ttttattatt
     3841 aatatataaa atttcttgac atacaactta aaaagagg
//
LOCUS       DBJKQU010000080         3748 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.080, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000080 DBJKQU010000000
VERSION     DBJKQU010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3748
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.080"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            74..550
                     /locus_tag="ACSUUC_001944"
     CDS             74..550
                     /locus_tag="ACSUUC_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055094.1"
                     /translation="MSRTYINIRLAYETKYWLECIQEEVQKKLDALINEQDIEELESI
                     ITNKLEKKDSLLGAVSITTFFKVSSSSVIEKAYNETKNYTTSEWREIARQMNLAKVKQ
                     NMEIGTLTPRLYLDNNIISELEKYQFLFKSDDMIRQVRMSYVIKMVAFAYYKKLFA"
     gene            721..1275
                     /locus_tag="ACSUUC_001945"
     CDS             721..1275
                     /locus_tag="ACSUUC_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055095.1"
                     /translation="MPKLLETEKYSLDSIIDGGKLRMISKFCPDLHGLRYEFKTSDSI
                     TKEYCKKIRQALRDSDPEGKSGKKCMMRYTIDILNVWNTLCRTRDFITGSLKADDVID
                     GKTGIYFFDVNTSNVITDDVIENVKINHKSLVRNVDEENIESISKEIPKGTDMYYYVL
                     YRLGLNRIKYNYLVKALAGAIQKD"
     gene            1509..1937
                     /locus_tag="ACSUUC_001946"
                     /pseudo
     CDS             1509..1937
                     /locus_tag="ACSUUC_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017865044.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rolling circle replication-associated protein"
     gene            1940..2053
                     /locus_tag="ACSUUC_001947"
                     /pseudo
     CDS             1940..2053
                     /locus_tag="ACSUUC_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            2057..3190
                     /locus_tag="ACSUUC_001948"
     CDS             2057..3190
                     /locus_tag="ACSUUC_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHQ8055096.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYMTKKEAIEAE
                     HYLRSVELKERFYGAKITISILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINKKLSQELQDWEKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            3231..3668
                     /locus_tag="ACSUUC_001949"
     CDS             3231..3668
                     /locus_tag="ACSUUC_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HHQ8055097.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVTTDEE
                     KAVAYLHDVIEDTTLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKTNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRTKKKS"
BASE COUNT         1496 a          523 c          655 g         1074 t
ORIGIN      
        1 caaaaatatt gttgacaaat agaaaatact gtgttaaaat gtctatataa cagagacagt
       61 tggaggtata agaatgagtc gtacttatat aaatataaga cttgcatacg aaaccaagta
      121 ttggttagaa tgtatacaag aagaggttca aaaaaaatta gatgctttaa ttaatgaaca
      181 agatatagag gagttagaat caatcatcac taataagtta gaaaaaaaag attctctatt
      241 gggggctgtt tccataacaa cttttttcaa ggtatcttct tcaagcgtga ttgaaaaagc
      301 ctataacgag acaaaaaatt acactacttc agaatggcga gaaattgcaa ggcaaatgaa
      361 tttggcaaaa gttaagcaaa acatggaaat tgggacgtta acacctagat tatatttaga
      421 taataatatt atttcagaat tagagaagta tcaattttta ttcaaaagtg atgatatgat
      481 aaggcaggta aggatgagct atgttattaa aatggtcgca tttgcctact ataaaaaatt
      541 gtttgcatga tttataagct cgataataag agcttataaa aatacaacct ttgtctgtgt
      601 taacgagact tttaaacttt ttaatcggaa ggagaatatt ttgataggag cgtcacctat
      661 tatttatttg acaacattaa ataaaaacta atattaaaaa aatataaagg aggagcagaa
      721 atgccaaaat tattagagac tgaaaaatac agtttagata gcattataga tggagggaag
      781 cttagaatga tttctaagtt ttgcccagac ttacatggct tgaggtacga attcaaaaca
      841 tcagactcaa ttactaaaga atattgtaaa aaaatacgtc aagctttaag agattctgat
      901 ccagaaggaa agagtggaaa aaaatgtatg atgagatata caatagatat tttaaatgta
      961 tggaacacgc tatgtagaac acgagatttt ataacgggga gtttaaaagc ggatgatgtt
     1021 atagatggga agacagggat atacttcttt gatgttaata cgtctaatgt aattacggat
     1081 gatgttatag aaaatgttaa aattaatcac aaaagcttag tacgaaatgt tgatgaagaa
     1141 aatatagaaa gtatttcaaa agaaattcct aaaggtactg atatgtatta ttatgttttg
     1201 tatagattag ggttgaatag gattaagtat aattatttag tcaaggctct ggcaggcgca
     1261 atacagaagg attaagaata taattatata attaaggggg agttttttct ccccttatag
     1321 agatagtatt attcttttgg tatttggggt atcgtttatc aatctcatct tatagctaat
     1381 aaaaatagtc tatgttttta gtgaaaaaaa tattatttta aggagtggtg atatgtatat
     1441 acttgtcaca aatgggaaaa gctacgtgac tttcccttgg ttgcgtgaaa tagcttgcag
     1501 aaattataaa ggagaaacta aggtgtttac tacaaaggaa ctctataatt tcctatatta
     1561 aacgctttaa ctatcacatt tttaatacca agaaaagtaa attaaaatat atagcagtat
     1621 tagagaggca aaaacgtaaa gcatggcata gtcatatttt gctattcagt gttccctata
     1681 ttccacataa gcaattatta gaactttggg ggcatggagc agtacggata aataaagttg
     1741 acgttgacag caaagaaaat cgcggtcgat atgtcacaaa gtattttgaa aaaggtattg
     1801 gacaagaatt gttggaaaac ttcggaaagc aagcctattt ttcatcacgc aacttgaaaa
     1861 agcctgatga agataaattt tacacttatg aagattttaa ctatgatagt tcagtcgtac
     1921 tatatgaaac ggaatacaac tgataacccg aggctttaca gtctatcaga acaagcgaat
     1981 tggtactata cctgctacta ttgctaccga attactcggt tttgatgttc aaaacagtac
     2041 cctcaaggag taaaatatgg caattagaaa aggtaaagac ggtaattggg tagttgatat
     2101 tagcaacggt tttgacccaa taacactaaa gcaacgtaga cttgtcagaa agggatatat
     2161 gacgaaaaaa gaagctattg aagcagaaca ctacttacga agtgtagagt taaaagaacg
     2221 cttctatggg gctaaaataa ctatctccat actatatgaa ctacttaagg aagaagatag
     2281 cataaatcat cgaaaagcaa gctatatcaa tacacaagat aataattaca acaaacacat
     2341 caaagattat ttttctatgg tcgataatgt cggaaaacta acctatgaag acatctacca
     2401 atttagagaa catcttaggc aaaaagtagc taaaaattct gataaaccgt taagcacaaa
     2461 tactattaac aaaatcatga ttttactcaa aaaaattttt gatgttggtt tgcgaaaagg
     2521 ctattactcc tccaatccag caaaattgat aaaaaagttg ccaattgaaa aaacaaaaat
     2581 gcaattttgg acagtcaaag aatttcagaa gtttttgaca ctatttgaac ccgaagaata
     2641 caatatcaaa ctactcttta ctgttctatt ctttacagga ttaagacttg gggaagctct
     2701 tgctctaaca tggcaagaca tcgacttttc aagtaataca attcatatca cgaaatctgt
     2761 ctatgttaat aaaggagtaa ctcatatcag cacaacaaaa actaaagcag gaacaagaag
     2821 aattgttatc aataaaaaat taagccaaga attacaagat tgggaaaagc gacaaaaaca
     2881 tctattagag caatttacca acaatagcct aacattacaa gtgtttcaaa atagtcctat
     2941 cacaattaca aaaaatgcta ttgaaaagca gtacaagaaa atcattgaac gtgatagtac
     3001 actaaaaaag atacgcatac acgattttag gcactcacac gcttccctgc tgattaacca
     3061 aggggaagat tatctagttg taaaagagcg actaggacat gcttctataa caaccacgat
     3121 tgatacctac tctcacttgt acccaagtaa gcaaaaggat ttagctgata aactagatga
     3181 tttactataa agtaattgag ttttataaat ggaaagttta taattaaatc atggatacat
     3241 cacaagtaat aaaagcacat gaagtagcta aaaaagcaca ctttggacaa attgatagag
     3301 caggaattga ctacattaaa caccctgaaa cagtagctag ttttgtcaca actgatgaag
     3361 agaaagctgt cgcctatcta catgatgtaa ttgaagatac tacactaacc ctactagacc
     3421 taaaaaagga aggtttttca aaaaacatta tagaagcagt cgatatactc acaaagaaaa
     3481 aaggacaaga ttatcaatct tatctcaatc tagtaaagac aaatgaactt gctagagttg
     3541 taaaattggc ggatttacgg cataattcag atttaaccag actaccatta attactgaaa
     3601 aagacttaga gagaaataag aaatacagtt ctgctattag atttttaaga acaaagaaaa
     3661 aaagttagta actaaactat aaaaatttat aaagagaaaa caaggcttat aaactttgtc
     3721 tttattacta tcttggcggt cagtctcg
//
LOCUS       DBJKQU010000081         3709 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.081, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000081 DBJKQU010000000
VERSION     DBJKQU010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3709
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.081"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            85..312
                     /locus_tag="ACSUUC_001950"
     CDS             85..312
                     /locus_tag="ACSUUC_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055098.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            600..3497
                     /gene="nanA"
                     /locus_tag="ACSUUC_001951"
     CDS             600..3497
                     /gene="nanA"
                     /locus_tag="ACSUUC_001951"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HHQ8055099.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGIEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1269 a          616 c          842 g          982 t
ORIGIN      
        1 aagatagatt gctgtaaaaa tagtagtagc tatgcgaaat aacagataga gagaagggat
       61 tgaagcttag aaaaggggaa taatatgata tttaaggcat tcaagacaaa aaagcagaga
      121 aaaagacaag ttgaactact tttgacagtt tttttcgaca gttttctgat tgatttattt
      181 cttcacttat ttgggattgt cccctttaag ctggataaga ttctgattgt gagcttgatt
      241 atatttccca ttatttctac aagtatttat gcttatgaaa agctatttga aaaagtgttc
      301 gataaggatt gagcagggag tatggtataa atagcataag ctgatgtcca tcatttgctt
      361 ataaagagat attttagttt aattgcagcg gtgtcctggt agataaacta gattggcagg
      421 agtctgattg gagaaaggag aggggaaaat tggcaccaat ttgagatagt ttgtttagtt
      481 catttttgtc atttaaatga actgtagtaa aagaaagtta ataaaagaca aactaagtgc
      541 attttctgga gtaaatgtct tatttcagaa atcgggatat agatatagag aggatcagta
      601 tgaatcggag tgttcaagaa cgtaagtgtc gttatagcat taggaaacta tcggtaggag
      661 cggtttctat gattgtagga gcagtggtat ttggaacgtc tcctgtttta gctcaagaag
      721 gggcaagtga gcaacctctg gcaaatgaaa ctcaactttc gggggagagc tcaaccctaa
      781 ctgatacaga aaagagccag ccttcttcag agactgaact ttctggcaat aagcaagaac
      841 aagaaaggaa agataagcaa gaagaaaaaa ttccaagaga ttactatgca cgagatttgg
      901 aaaatgtcga aacagtgata gaaaaagaag atgttgaaac caatgcttca aatggtcaga
      961 gagttgattt atcaagtgaa ctagataaac taaagaaact tgaaaacgca acagttcaca
     1021 tggagtttaa gccagatgcc aaggctccag cattctataa tctcttttct gtgtcaagtg
     1081 ctactaaaaa agatgagtac ttcactatgg cagtttacaa taatactgct actctagagg
     1141 ggcgtggttc ggatgggaaa cagttttaca ataattacaa cgatgcaccc ttaaaagtta
     1201 aaccaggtca gtggaattct gtgactttca cagttgaaaa accgacagca gaattgccaa
     1261 atggtcgagt tcgcctgtat gttaatggtg ttttatctcg aacaagtctg aaatctggca
     1321 atttcattaa agatatgcca gatgtaacgc atgtgcaaat cggagcaacc aagcgtgcca
     1381 acaatacggt ttgggggtca aatctacaga ttaggaatct cactgtgtat aatcgtgctt
     1441 taacaccaga agaggtacaa aaacgtagtc aactttttaa acgctcagat ttagaaaaaa
     1501 aactacctga aggagcggct ttaacagaga aaacggacat attcgaaagc gggcgtaacg
     1561 gtaaaccaaa taaagatgga atcaagagtt atcgtattcc agcacttctc aagacagata
     1621 aaggaacttt gatcgcaggt gcagatgaac gccgtctcca ttcgagtgac tggggtgata
     1681 tcggtatggt catcagacgt agtgaagata atggtaaaac ttggggtgac cgagtaacca
     1741 ttaccaactt acgtgacaat ccaaaagctt ctgacccatc gatcggttca ccagtgaata
     1801 tcgatatggt gttggttcaa gatcctgaaa ccaaacgaat cttttccatc tatgacatgt
     1861 tcccagaagg gaagggaatc tttggaatgt cttcacaaaa agaagaagcc tacaaagaaa
     1921 tcgatggaaa aacctatcaa atcctctatc gtgagggaga aaaggaagct tataccattc
     1981 gagaaaatgg tactgtctat acaccagatg gtaaggcgac agactatcgc gttgttgtag
     2041 atcctgttaa accagcctat agcgacaagg gtgatctata caagggtgac caattactag
     2101 gaaatatcta cttcacaaca aacaaaactt ctccatttag aattgccaag gatagctatc
     2161 tatggatgtc ctacagtgat gacgacggga agacatggtc agcgcctcaa gatattactc
     2221 cgatggtcaa agccgattgg atgaaattct tgggtgtagg tcctggaaca ggaattgtac
     2281 ttcggaatgg gcctcacaag ggacggattt tgataccggt ttatacgact aataatgtat
     2341 ctcacttaaa tggctcgcaa tcttctcgtg tcatctattc agatgatcat ggaaaaactt
     2401 ggcatgctgg agaagcggtc aacgataacc gtcaggtaga cggtcaaaag atccactctt
     2461 ctacgatgaa caataaacgt gcgcaaaata cagaatcaac ggtggtacaa ctaaacaatg
     2521 gagatgttaa actctttatg cgtggtttga ctggagatct tcaggttgct acaagtaaag
     2581 acggaggagt gacttgggag aaggatatca aacgttatcc acaggttaaa gatgtctatg
     2641 ttcaaatgtc tgctatccat acgatgcacg aaggaaaaga atacattatc ctcagcaatg
     2701 caggtggacc gaaacgtgaa aatgggatgg tccacttggc acgtgtcgaa gaaaatggtg
     2761 agttgacttg gctcaaacac aatccaattc aaaaaggaga gtttgcctat aattcgctcc
     2821 aagaattagg aaatggggag tatggtatct tgtatgaaca tactgaaaaa ggacaaaatg
     2881 cctataccct atcatttaga aaatttaatt gggacttttt gagcaaaaat ctgatttctc
     2941 ctaccgaagc gaaagtgaag cgaactagag agatgggcaa aggagagatg ggcaaaggag
     3001 ttattggctt ggagttcgac tcagaagtat tggtcaacaa ggctccaaca cttcaattgg
     3061 caaatggtaa aacagcgact ttcctaaccc agtatgatag caagaccttg ttgtttgcag
     3121 tagataagga agatatcgga caagaaatta ttggtatagc taaaggaagc atcgaaagta
     3181 tgcataatct tcctgtaaat ctagcaggtg ccagagttcc tggcggagta aatggtagca
     3241 aagcagcggt gcatgaagtt ccagaattta cagggggagt taatggtata gagccagctg
     3301 ttcatgaaat cgcagagtat aagggatctg attcgcttgt aactcttact acaaaagaag
     3361 attatactta caaagctcct cttgctcagc aggcacttcc tgaaacagga aacaaggaga
     3421 gtgacctcct agcttcacta ggactaacag ctttcttcct tggtctgttt acgctaggga
     3481 aaaagagaga acaataagag aagaattcta aacatttgat tttgtaaaaa tagaaggaga
     3541 tagcaggttt tcaagcctgc tatctttttt tgatgacatt caggctgata cgaaatcata
     3601 agaggtctga aactactttc agagtagtct gttctataaa atatagtaga ttgaaataag
     3661 atgtgaacaa ctctatcagg aaagtcaaat taatttatag aattatttt
//
LOCUS       DBJKQU010000082         3456 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.082, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000082 DBJKQU010000000
VERSION     DBJKQU010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3456
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.082"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            277..1822
                     /locus_tag="ACSUUC_001952"
     rRNA            277..1822
                     /locus_tag="ACSUUC_001952"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1874..1946
                     /locus_tag="ACSUUC_001953"
     tRNA            1874..1946
                     /locus_tag="ACSUUC_001953"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1907..1909,aa:Ala,seq:tgc)
     gene            2071..>3456
                     /locus_tag="ACSUUC_001954"
     rRNA            2071..>3456
                     /locus_tag="ACSUUC_001954"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          993 a          693 c         1012 g          758 t
ORIGIN      
        1 acgggttcga atcccgtacg gactatggta tgttgcgtca ggaccacttg atgaaaaaaa
       61 gtttaaaaaa acttaaaaat cttcaaaaaa gtgttgacaa gtgaaagtgg ctgtgatata
      121 ctaatatagt tgtcgcttga gagaagcaag tgacaaagac ctttgaaaac tgaacaagac
      181 gaaccaatgt gcagggcgct acaacataag ttgtagtact gaacaatgaa aaaacaataa
      241 atctgtcagt gacagaaatg agtgagaact caaactttta atgagagttt gatcctggct
      301 caggacgaac gctggcggcg tgcctaatac atgcaagtag aacgctgaag gagaagcttg
      361 cttctctgga tgagttgcga acgggtgagt aacgcgtagg taacctgcct ggtagcgggg
      421 gataactatt ggaaacgata gctaataccg cataagagtg gatgttgcat gacatttgct
      481 taaaaggtgc acttgcatca ctaccagatg gacctgcgtt gtattagcta gttggtgggg
      541 taacggctca ccaaggcgac gatacatagc cgacctgaga gggtgatcgg ccacactggg
      601 actgagacac ggcccagact cctacgggag gcagcagtag ggaatcttcg gcaatggacg
      661 gaagtctgac cgagcaacgc cgcgtgagtg aagaaggttt tcggatcgta aagctctgtt
      721 gtaagagaag aacgagtgtg agagtggaaa gttcacactg tgacggtatc ttaccagaaa
      781 gggacggcta actacgtgcc agcagccgcg gtaatacgta ggtcccgagc gttgtccgga
      841 tttattgggc gtaaagcgag cgcaggcggt tagataagtc tgaagttaaa ggctgtggct
      901 taaccatagt aggctttgga aactgtttaa cttgagtgca agaggggaga gtggaattcc
      961 atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc ggtggcgaaa gcggctctct
     1021 ggcttgtaac tgacgctgag gctcgaaagc gtggggagca aacaggatta gataccctgg
     1081 tagtccacgc tgtaaacgat gagtgctagg tgttagaccc tttccggggt ttagtgccgt
     1141 agctaacgca ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa
     1201 ttgacggggg cccgcacaag cggtggagca tgtggtttaa ttcgaagcaa cgcgaagaac
     1261 cttaccaggt cttgacatcc ctctgaccgc tctagagata gagttttcct tcgggacaga
     1321 ggtgacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg
     1381 caacgagcgc aacccctatt gttagttgcc atcatttagt tgggcactct agcgagactg
     1441 ccggtaataa accggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgacctg
     1501 ggctacacac gtgctacaat ggctggtaca acgagtcgca agccggtgac ggcaagctaa
     1561 tctcttaaag ccagtctcag ttcggattgt aggctgcaac tcgcctacat gaagtcggaa
     1621 tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt tcccgggcct tgtacacacc
     1681 gcccgtcaca ccacgagagt ttgtaacacc cgaagtcggt gaggtaaccg taaggagcca
     1741 gccgcctaag gtgggataga tgattggggt gaagtcgtaa caaggtagcc gtatcggaag
     1801 gtgcggctgg atcacctcct ttctaaggat aaggaactgc gcattggtct tgtttagtct
     1861 tgagaggtct tgtggggcct tagctcagct gggagagcgc ctgctttgca cgcaggaggt
     1921 cagcggttcg atcccgctag gctccattgg tgagagatca ccaagtaatg cacattgaaa
     1981 attgaatatc tatatcaaat agtaacaaga aaataaaccg aaaacgctgt agtattaata
     2041 agagtttatg actgaaaggt cagaaaataa ggttaagtta ataagggcgc acggtggatg
     2101 ccttggcact aggagccgac gaaggacgtg acaaacgacg atatgccttg ggtagctgta
     2161 agtaagcgat gatccaggga tttccgaatg ggggaaccca acaggtaata cctgttaccc
     2221 acatctgtta aggatgtgag gaggaagacg cagtgaactg aaacatctaa gtagctgcag
     2281 gaagagaaag caaaagcgat tgccttagta gcggcgagcg aaacggcaga agggcaaacc
     2341 gaagagttta ctcttcgggg ttgtaggact gcaatgtgga ctcaaagatt atagaagaat
     2401 gatttgggaa gatcagccaa agagagtaat agcctcgtat ttaaaatagt ctttgtactt
     2461 agcagtatcc tgagtacggc gggacacgtg aaatcccgtc ggaatctggg aggaccatct
     2521 cccaacccta aatactccct agtgaccgat agtgaaccag taccgtgagg gaaaggtgaa
     2581 aagcaccccg ggaggggagt gaaatagaac ctgaaaccgt gtgcctacaa caagttcgag
     2641 cccgttaatg ggtgagagcg tgccttttgt agaatgaacc ggcgagttac gttatgatgc
     2701 gaggttaagt tgaagagacg gagccgtagg gaaaccgagt ctgaataggg cgccttagta
     2761 tcatgacgta gacccgaaac catgtgacct acccatgagc aggttgaagg tgcggtaaga
     2821 cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg tgggtagcgg
     2881 agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt agggctagcg
     2941 tcgacattag agattcttgg aggtagagca ctgtttgggt gaggggtcca tcccggatta
     3001 ccaatctcag ataaactccg aatgccaatg aattatggtc ggcagtcaga ctgcgagtgc
     3061 taagatccgt agtcgaaagg gaaacagccc agaccaccag ctaaggtccc aaaataattg
     3121 ttaagtggaa aaggatgtgg ggttgcacag acaactagga tgttagctta gaagcagcta
     3181 ttcattcaaa gagtgcgtaa tagctcacta gtcgagtgac cctgcgccga aaatgtaccg
     3241 gggctaaaac aatttaccga agctgtggat acctttatag gtatggtagg agagcgttct
     3301 atgtgtgatg aaggtatacc gtgaggagtg ctggaacgca tagaagtgag aatgccggta
     3361 tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggttt ccaggggaag
     3421 gctcgtccgc cctgggttag tcgggaccta aggaga
//
LOCUS       DBJKQU010000083         3335 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.083, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000083 DBJKQU010000000
VERSION     DBJKQU010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3335
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.083"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(244..855)
                     /gene="rpsD"
                     /locus_tag="ACSUUC_001955"
     CDS             complement(244..855)
                     /gene="rpsD"
                     /locus_tag="ACSUUC_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HHQ8055100.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1050..2102)
                     /locus_tag="ACSUUC_001956"
     CDS             complement(1050..2102)
                     /locus_tag="ACSUUC_001956"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HHQ8055101.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2099..2797)
                     /locus_tag="ACSUUC_001957"
     CDS             complement(2099..2797)
                     /locus_tag="ACSUUC_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHQ8055102.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2964..>3335)
                     /locus_tag="ACSUUC_001958"
     CDS             complement(2964..>3335)
                     /locus_tag="ACSUUC_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HHQ8055103.1"
                     /translation="LDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHA
                     TGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGF
                     LGLALAGLLGGLGLKNKKEEN"
BASE COUNT          933 a          748 c          637 g         1017 t
ORIGIN      
        1 ctacctgttc gctcacaata agagagaact tttttacgaa aatctattga atattccata
       61 aaagattata ccacattgtg tactattttt ggttcatttt actatatcac tttggactat
      121 atcggtctag ttatgtctaa acgattatag ctggatacta agagaaatca aaaaagcact
      181 aagggagaac gtcccaaagt gcttaatatc aaggcctcaa agcctgtctt attcaataaa
      241 atattacaac atcttgttgt agaattcaac gacaagtgct tcgttgattt ctgggttgat
      301 ttcgtcgcgt tctggcaagc gagtcaatga accttccaat ttttcagcgt cgaatgatac
      361 gaatgctgga cgtccaagag tagcttctac tgcttcaagg attgctggaa ctttcaatga
      421 tttttcacga actgagatca cttgacctgg agttacgcgg tatgatggga tatcaacgcg
      481 tttcccgtca acaaggatgt gaccgtggtt tacgaattga cgagcttgac gacgagtagt
      541 cgcgagacca agacggtaaa caacgttatc caaacgacgt tccaaaagaa gcataaagtt
      601 gaaacctagg attccgcctt tgatttttgt agcttgtacg aacaagttac ggaattgttt
      661 ttcacctaca ccgtaagtga aacgaagttt ttgtttttca gccaattgca aaccgtattc
      721 tgacaattta gaacggttgt ttggtccgtg ttgtcctggt acgtagttac gacgtgccaa
      781 ttctttacct gtacctgtaa gtgaaaggcc aaggcgacga gcttgtttcc aagatggtcc
      841 tgtataacgt gacatatgaa tgtcctcctg atataaataa tatttcggtg gaaatagtca
      901 cttagaaagc cctgattcgt gcagatgccc ttcgcctaaa cagccaaggt tacttgtcat
      961 aagacacctg ttgacgagct tcatgctttc ctgctgatat ttcacacaaa atctattcta
     1021 ccatgaatag ctggatttgt aaaggggttt taggctttat tttcactacc agagaggttg
     1081 agaacgaggg taaaggtact tcctagaccg tactggctgc tgactgtgat ttccccaccc
     1141 aattgatggg ccaattcacg cgcaatcgca agtcctaatc catgaccacc tgtcttcatg
     1201 ttacgcgaag tttcgacacg ataaaggcgt ttgaaaatat tttccaaatc ctctggggca
     1261 ataccctgcc cttcatcggt cacactgatt gaaagctggt ccttctccag cttagccacc
     1321 acttccagct tggttcctgg agcagaatat ttaaaagcgt tatcgaccag attcaccaag
     1381 atacgagaaa gcttagcata atctccctca atccgggcag actctgggat tacctgcaag
     1441 tggacatctc ttctctcctg ctcaatcaaa aactgaaatt cactcatgca ctcaattaag
     1501 agcttgtcca gaaaaatact gtctttactg gtagtttcca cctgatttct agctgtgttt
     1561 agggtcaaaa aattcaactc ctcaaccagt ttattgagcc tctccgtctg gcgtccaatg
     1621 gttgctagat aatgagcttg ctccgactcc ttgataatac catccaaaat cccttctacc
     1681 gtcgcttgga tcgaagtgat aggagtctta atatcatgcg acaactgggc aatcatcaag
     1741 cccttttctc gttcgctttc ttccaaggaa tcaaagctta cctgcaaatc atgggacatc
     1801 tcattaaaag tttgccctaa ttgctgaaat tctacaggac cttgaacctc caaatttgaa
     1861 ggaaaatcct tggccgctac ccgcttggca tgctccttga gtttgcccaa cgacgtaaag
     1921 actggcaata ggagaaagag actaatccca gcaccgacaa ggctggcaac gatggtcatc
     1981 ccaagcaaaa agtaaatctc gcctttcgca atcagcattt tttgaacagc ccaaaaaaca
     2041 accaaaatgg ttaagagggt tgaaataata tatccaacca aaatataact ttttagtttc
     2101 atgtttgtcc tctcggtttc tctatcttat atcccaaccc ccaaactgtc ttaatagtgg
     2161 gcgtttggtc actactatat tttgccagct cctgtcgaag agcatggata tgcacattca
     2221 aggtattggt gtcatccacg tagtcttctt tccagatctt ttcatagagg tctgtcttgg
     2281 agaaaactcg ctctggattg ctagctaaaa tccacagcaa ttcaaatgat ttaacagtta
     2341 aatccagcat ttcttctcct atttgaactt catgactact atgattcatt tttagattgc
     2401 caagggaaat cagctctgtt tcgcccccac gatgaaggcg gcgcaaaata ttgtggacac
     2461 gcaaaaccag ctcacgtggg ctaaaaggct tagcaataaa atcatctgct cccaagctca
     2521 ggccgtaaat cttgtcctgt tcactggtct tagcagtaat aaataggaaa ggctgctctg
     2581 gtgataagta ttgaacctca ctgattaaat cataaccatc catccgaggc atcatgacat
     2641 ctgtgataat caaatcaatc ggttttttct tgaacagctc tagcgcttcc agtccatcat
     2701 gggctaccaa gacctgataa cctgcctgaa ttaagtatct ctgatgaata tctgtgattt
     2761 ctacctcgtc gtcaacgagt aaaattgtct ttcccatctg tctctccttt gataaaaaca
     2821 gtgctatact gctttaagta taacactatt tttattgttt tacgatgatt ttaatctgct
     2881 attgaaagaa agtcctgatt gctgattgag ttgttaaact agtcttagtc agcccactat
     2941 ccatcattta tttccttagc tgattagttt tcttcttttt tgtttttcaa acctagacca
     3001 ccgagtaaac ctgcaagcgc aagcccaagg aaaccaatac ttgccattga tgtttgagtc
     3061 tcaccagtat ttggtagcat agctttatcc tctgacatca tcgtatcaga catcttgtta
     3121 gcagaagcag ccatgttttc acctgccatc gtgttggtag aacttgtcat ggtgtcagca
     3181 ggcatgctat ctgtagtacc tgtagcatga ttgtgattca tcggagtcac gccagaacca
     3241 gagttagaag gtgataatga accatttgct gtgtctgatg tttctttaac atttatctta
     3301 atagtgactt ttttagttgc tacgatgttg tccaa
//
LOCUS       DBJKQU010000084         3199 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.084, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000084 DBJKQU010000000
VERSION     DBJKQU010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.084"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(27..1382)
                     /gene="rlmD"
                     /locus_tag="ACSUUC_001959"
                     /pseudo
     CDS             complement(27..1382)
                     /gene="rlmD"
                     /locus_tag="ACSUUC_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
     gene            1420..2196
                     /gene="recX"
                     /locus_tag="ACSUUC_001960"
     CDS             1420..2196
                     /gene="recX"
                     /locus_tag="ACSUUC_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HHQ8055104.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2285..2818
                     /gene="ntdP"
                     /locus_tag="ACSUUC_001961"
     CDS             2285..2818
                     /gene="ntdP"
                     /locus_tag="ACSUUC_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017110 - nucleoside diphosphate
                     phosphatase activity [Evidence IEA];
                     GO_function: GO:0017111 - ribonucleoside triphosphate
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside tri-diphosphate phosphatase"
                     /protein_id="HHQ8055105.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
BASE COUNT         1025 a          582 c          560 g         1032 t
ORIGIN      
        1 ctttttatgt tttgtcaaca ccttttttaa acttttttta ttaattttac aacagcttca
       61 gttcgagctg tatgtgggaa catatcgacc gactggatat aatgaagatc atagacttct
      121 actaagcgta ccaaatcacg agccaaggtc gaaacattac aagaaatata aaccattttt
      181 tctggtacat aagtaagaat agtatctaat aacttatcat ccagacctgt acgtggtggg
      241 tcaacaatca aagcatctgc tcggtagcct tccttgtacc aacgaggaat aatctcttct
      301 gccgttccag cttcataatg agtattgtca aatcccattc ttttagcatt tcgcttggca
      361 tcttcaatag cttctggaat aatatccata cctctgagtg tttttacttt ctttgcaaag
      421 gcaaatccaa tcgttccaac tccacaataa gcgtcaatca aatggtcttc tttatcaaca
      481 tccagcgctt ttactgcttc gctatagagg acttctgttt actcaggatt tagttgataa
      541 aaagctcgag gggatagtga aaattcataa ttgagtacac cttcttgaat actctcttgc
      601 ccccagataa tctctgtctt ttcaccatat atctcactgg ttttagctgt atttgtatta
      661 acagctactg tcacaacttc tgggaaatct ttaaccaact cttttaccaa ttgagttaaa
      721 ttaagctggc ggtttgtaac aataataatc tgaacctgtc cggtctttct cgcgcgtcgg
      781 accataatag tacggacacc tagaactttt ctctcatccg tgattggaat ctggtgataa
      841 gtaagtaatt ctgctaagcg attagcaatc acttgggttt ccttatcttg taccaggcag
      901 tctttcaact ctactaaata gtgagagttt tgtgcatata agcccgcctt gacctgattt
      961 ttaaattttc gagtctgaaa ttgtaactta gctctgtaat attttggttc ctgcattcca
     1021 atagttggac gaatttcata attttcatat cctgcaggag caaatttttt cagcgcttga
     1081 tgaagtaagt ccgtcttgaa ctccagctgc ttatcataat gcaggtgcat gatttggcag
     1141 cctccgcatt cattataaat agtacaagat ggcacaattc gaaatttaga cttcttgttg
     1201 accttcagta attttgcttc aacaaagttg cgtctaatag aagtaatctg acaatagata
     1261 tcttcgcctt tgagagctcc tggtacaaag actaatgttt tttggtaaaa gccgattccc
     1321 tcaccgttaa ttcccatgcg cttgattttt aatggtattt tttgtttcac tttcagattc
     1381 atacccctat cttatcacat tttgagttat aatagagcta tgaaaatcac aaaacttgaa
     1441 aagaaaaaaa gactctatct gatggagctt gataatggcg acaaatgcta tatcaccgaa
     1501 gatacaattg ttcgttttat gttatcgaga gataaggtga taagcgaaga ggaattgaaa
     1561 gagattcaag actttgctca attttcttat ggtaagaatc tggccctcta ccacttatcc
     1621 tttaaagcac gcactgaaaa agaagtcaga gaatatctga aaaaatacga tattgataaa
     1681 aacattgttt ctcaagttat tgctaatctt aaagaagata agtggattaa tgatggtcag
     1741 tacgcttatg ctatcatcaa taccaatcaa ctttcaggag acaagggtcc ttatgtgctg
     1801 actcaaaaac tagctcaaaa agggatttca aaatctacta tagaagagaa cttgaaagaa
     1861 tttgattttt ctgaagttgc tcaacgtgta gctaataaac tattgaaaaa atatgaggga
     1921 aaacttccat ctcgtgccct gcaagataag attatccaga acttgactaa caagggcttc
     1981 tcttattctg atgctaaaat tgcctttgac gacttagata gccaagttga ccaagaaacg
     2041 actcaagaac tcatcttcaa ggaacttgat aagcaatata ctaagtatgc tcgaaagtat
     2101 gaaggatacg aactgaagca gcgtttaact caagttttag cacgaaaggg ctacgatttt
     2161 tcggatatag caagcgctct tagagaatat ctttaatatt tccaagtgaa attcacagat
     2221 tttaggtaat tttatggtac aatagtaaat gataaactta taaattgtag aaagttggtt
     2281 agttatgaag cttccaaaag aaggcgactt tattacaatt caaagttata agcatgatgg
     2341 gagtctccac cgaacttggc gggacaccat ggtactaaaa acaacagaaa acgccattat
     2401 tggtgtcaac gatcatacac ttgttaccga aagtgatggt cgtcgttggg tcactcgaga
     2461 accggctatt gtttactttc acaagaaata ttggtttaat atcattgcca tgattcgtga
     2521 taatggaact tcttactatt gcaatatggc tagcccctac tatctggatg aagaagcact
     2581 gaagtatatt gattacgatt tggatgttaa aatttttaca gatggggaaa aacgtctctt
     2641 ggacgttgaa gagtacgagc gtcacaaacg caaaatgaat tattctgatg acttggacta
     2701 tattttaaaa gaacatgtca aaattcttgt tgattggatt aacaatggac gtggtccttt
     2761 ctcagaagcc tatgtaaaca tttggtacaa gcgctatgta gaactaaaga atcggtaaag
     2821 ttgtcaaagg tcaggaacaa aatcctgacc ttgttttttt ggtagtataa aataaattgt
     2881 gtaaacacaa aaaggaataa atccattata gcagagttac aacacattac tagaaagaga
     2941 tttattccta cgactcagtt tggcatgctt aacttcctaa ctcaaaaaca aagcatcgat
     3001 taatttatcc gttcttcttt tgaaacagat ttgaactgat aattgctcgt tttaatttaa
     3061 gaagctcttt tgagcaaaac ttcatttttt taagagtcca acaatttctg tctatcgctt
     3121 ttctactagc aaaaaaaact accttgaggc aagttttcat ttatatatct aatttcgtaa
     3181 tagtatagta aaatgaaat
//
LOCUS       DBJKQU010000085         2852 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.085, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000085 DBJKQU010000000
VERSION     DBJKQU010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.085"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(<1..442)
                     /locus_tag="ACSUUC_001962"
     CDS             complement(<1..442)
                     /locus_tag="ACSUUC_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055106.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFLNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFD"
     gene            complement(500..1213)
                     /locus_tag="ACSUUC_001963"
     CDS             complement(500..1213)
                     /locus_tag="ACSUUC_001963"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HHQ8055107.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIGRDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1672..2052)
                     /gene="dhaM"
                     /locus_tag="ACSUUC_001964"
     CDS             complement(1672..2052)
                     /gene="dhaM"
                     /locus_tag="ACSUUC_001964"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HHQ8055108.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            complement(2052..2126)
                     /locus_tag="ACSUUC_001965"
                     /pseudo
     CDS             complement(2052..2126)
                     /locus_tag="ACSUUC_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397816.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
     gene            complement(2474..>2852)
                     /locus_tag="ACSUUC_001966"
     CDS             complement(2474..>2852)
                     /locus_tag="ACSUUC_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HHQ8055109.1"
                     /translation="RNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPK
                     PTEEPEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLF
                     GTQDNNTIMAEAEKLLALLKESK"
BASE COUNT          877 a          552 c          449 g          974 t
ORIGIN      
        1 cgtcaaaatt agaaaaaaat cgaaaataca atgcattctc ttggtgtaaa atcgctcttt
       61 ttaaaggata atactcttta atattattaa ctttttgttc gtaggcatat tttgctacat
      121 gatctaggta tatatcaaaa aagtcatgag gaaaatctcc catacagcca ttacgattca
      181 tattgaggct atattttcga ttagtaagat aattcagaaa tatatttcct attactctaa
      241 gattatctac ttgtgaatcc cttctcccaa tataatcccc ttctttgact aatgatggag
      301 atttccaagt aaaaattaaa tcgccagaga aatttttctt atcaaaaaac ttaaaaagag
      361 attgataaat actatttgct aattgacaag tgtcagatgt aaattcataa ttaacagctt
      421 cattaaaatc aacttcagac atttcaatgt actcttcaat agtaatatta gcttttttgt
      481 agtcattagc tcgtctcctt taaaatgtga tcttttcaag aatattttta tctaaacaat
      541 ccagcaagtc ttggtaagaa tagacttcgt aagtcggctg ggcttgtgtg tgattttcga
      601 ggtgatgagg attataccag atagtgtcaa tccccgcatt attgccacct tgaatgtcgg
      661 cggttagaga atctccaatc atcagcgtct tttctttact aaatccagca atttgctggc
      721 caatcttttc ataaaaaaga gcatccggct tttgagtttg caactgttct gagataaaga
      781 cttgattgaa ataaggtgct agaccagatt gagccaaacg tcctgtctga atggcagtaa
      841 tgccatttgt cgcagcatac aagttataat cacgcccaat gaggctgtcc aagagatcat
      901 gagcgcccga tagtgtttgt ccctgctggg cgaggtaaaa ttggtaacgc tgggcaagaa
      961 aactaccgtc tttttcttgt ccaaaatgag caaataaacg agaaaagcgc gtgttaacca
     1021 gctcttgttt actgattttc ttcagctcca agtctttcca gagagccttg ttcataggaa
     1081 cgtaataatc tttataagcc tgaatatccg caactccttc ttcttttaga agttgggtca
     1141 aagccacatc ctcagcagca tcaaaatcaa gaagagtgtg gtcgaggtcg aagagtagaa
     1201 atttgtagaa caatttgagg ttttcctttc tgaaaattca ttaagaacat tatatcataa
     1261 agcacctcat acaattaact aatttaatca cttaaaaaaa attcgaacac tttctataca
     1321 actgacagct caaatctttc agaatagaac aatactaact atcgaacacc ctgtcttcat
     1381 aaatacatat gtaattctag gcctagaatt cctataaact aaatgctttc atactcttcc
     1441 aagtaattga ttgccttaaa ttttaatttt tgaaggtttc taaagctaga atagccccat
     1501 cacaatcagt tttgattgat tcacaattta gaaacactat agtttcactc ctgttaaaat
     1561 aaaaaggaac tgcataaagc aatccctttc tgattttgaa atcatttact taacatttta
     1621 tagttgagat aatcaatagc ttatctataa aaagagttat agtaaaattc cttatttatt
     1681 gatttcaagc tccgctaact gtatttgaat aactgacagt tctgcaccag cctgaagaag
     1741 agcagctgca ttataggcac cttctacaat tggaaccctg ttgatgatga tacttttatc
     1801 actgaaatca gtcaccattt ttaagttcat tttagcagaa cctaggtcaa aaaaggcaag
     1861 taaagtatct gctggatttt cggaaacaac cctatctact tgatcaaaac tcgttccaat
     1921 tcctccgccc tcggttcctc ctacataagt aatcggaaca tctttagcta ctttactaat
     1981 cagttcaaca acaccttctg caatgtgttt ggaatgtgaa acgataacaa gaccaatacc
     2041 aatactttcc atcaaaccac tccagtttct aaaatagcag taaagagtaa tcctgatgag
     2101 aatgatccag gatcaatatg tccaagaaac cacatgctcc taagacaaga gctaacagac
     2161 tggccatcaa taatagtatt gttctttttt tcatcattac tccttaacta gtgtttaact
     2221 gattaattag ccagtaaata gtttatcttt atttacacta tctgttaaga tatagtaaaa
     2281 tgaaataaga acaggacagt caaatcgatt tctaacaatg ttttagaagt agaggtatac
     2341 tattctagtt tcaatctact atattttgca cattttcatg aaaaaaatga gaactagaac
     2401 tcacattctg ctctcatttt tcgttttccc gttctcctat cctgttttta ggagttagaa
     2461 aatgctgcta cctttactta ctctccttta ataaagccaa tagtttttca gcttctgcca
     2521 taatagtatt gttgtcctgg gtgccaaata gtaaattatt ttttaatcct gtgagagtct
     2581 ctttggcatt ggacttgata attggatcct ggatttttcc aagtaaatct tcagcctctc
     2641 tcagtttttc ttcaaccttt tcagtctcga cctgaggttc ttctgattcc tctggtgatt
     2701 cttctggttc ctctgttggt tttggagact ctggtttctc gctttgcggt ttctcttctc
     2761 gaggggtttc ttcctcaggt ttttctgtct gaggtttctc ctcgcttggt ttttccgttt
     2821 gattggtatc agcttgacca tttttgtttc tt
//
LOCUS       DBJKQU010000086         2613 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.086, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000086 DBJKQU010000000
VERSION     DBJKQU010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.086"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..116
                     /locus_tag="ACSUUC_001967"
     CDS             <1..116
                     /locus_tag="ACSUUC_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HHQ8055110.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK"
     gene            140..1063
                     /locus_tag="ACSUUC_001968"
     CDS             140..1063
                     /locus_tag="ACSUUC_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HHQ8055111.1"
                     /translation="MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSK
                     VQSNKIRVYDEKFNLLYEQDGKISPDKGITIEVENEIYYILGSSIYRITIGESVEETC
                     IGNFDFQLESGYGCYFDGHLFFGFQESYLFNIETQELFKKSDFPVSGRGQGLSVKYQN
                     ELYYLGGANNEAYLDGYKYSLKKDKWEKLEFELPSSVLGASSIQINESGLLILGGFNE
                     IVYNKAVIDLATPGYREEYFSKGRDFFNWNRSMRILDLETGKVKIIANDERFALCGAG
                     FLKTDNGYYVVSGECSPGRRTSDILLLEEEM"
     gene            1145..>2613
                     /locus_tag="ACSUUC_001969"
     CDS             1145..>2613
                     /locus_tag="ACSUUC_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHQ8055112.1"
                     /translation="MKKIVKLALTAAAVLIAVVGLVACSSGSKKSDFSESGKEKVFYL
                     SGFLQGTGDRIPYVWQNGDGLVPYLLYRTLLMADSKYEKSTPDLAKDWKKSDDEKTYE
                     FTLKDGLKWSDGEALTASDVEFSVKLALKASVINGIFPSTFTKIEGAKDFKDDKADKI
                     SGLTVDGNKVTFKLTAPVGDFEQMMTQFFILPKHKLESENPLELNNSSFWTAPVTSGM
                     YKVKEISAGNFLEYDKNENYENEKPKFDKVVFNYISDPVLALQDGKSYFYSTNKPQEI
                     SQLDAVSTLSKKPIDILFYRYFIANLAGVEGNGDSLIANPKVREAILYAINRDELAKS
                     VFSGIADVNNTGVPSSLEAHLKSANKFEYNPEKAKQLLKEAKYDNSRNLILAYYYKDQ
                     ASQDFMQAVSYQLNEVGIKNEVVQITSDATTGLFKTRKYDLAYKGLSSFGYETWYGEY
                     SSTNTNFKNITNGETSFDELSKKLSETSDVKERNKILASL"
BASE COUNT          957 a          342 c          493 g          821 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgctattac tagaccaaaa gagattacag aacgttttgt agcgggatta aaatagcatg
      121 ccagagtaag aggtgtaata tgaaaattga tgttataaat catttagact caccaggatt
      181 agctgggatg atttgtagac ggattaataa tagaatttta gtttatggag gtagttattt
      241 cccaaataac gatcctttaa aaagttcaaa agttcaatca aataaaatta gagtttatga
      301 tgagaaattt aatcttctat atgaacaaga tggaaaaatt tctccagata aaggaataac
      361 gattgaagtt gaaaatgaaa tctattacat tctaggctcg agcatttatc gtattacgat
      421 tggtgaaagt gtagaagaaa cctgtatcgg gaattttgat ttccaactag agagtggtta
      481 tggttgttat tttgatggcc acttattctt tggatttcag gaaagttatt tgttcaatat
      541 tgagactcaa gagcttttta aaaaatctga cttcccagtt tctggtagag gccaaggttt
      601 gtcagtcaaa tatcaaaatg aattgtatta tttaggtgga gcgaacaatg aagcttattt
      661 agatggatac aaatatagtt taaaaaaaga taagtgggaa aaacttgagt tcgaattacc
      721 aagctcagtt ctaggagcat caagtataca aataaatgaa agtggtttat taatacttgg
      781 tggctttaat gaaattgttt ataataaagc agttattgat ttagcaaccc ctggctatag
      841 ggaagaatat ttttctaaag ggagagattt ctttaattgg aatcgtagca tgcgaatact
      901 agatttagag acaggtaagg tcaagattat tgcaaacgat gagcgttttg ctctttgtgg
      961 ggcaggattt ttaaaaactg ataatggata ttacgttgtt agtggggaat gtagcccagg
     1021 aagacgtact tctgacatac ttttgttaga ggaggaaatg taacgaagag tttaaatttt
     1081 taattactgc aatacttact taatcacata aataattact taatacaaat aaaggagtat
     1141 taaaatgaaa aaaattgtta aattagcttt aacagctgca gcagttttaa tagctgtagt
     1201 aggattggtt gcttgtagtt cgggaagcaa aaaatctgat ttttcagagt ctggaaaaga
     1261 aaaagtattc tatttatcag gttttcttca aggaactgga gatcgtatcc cttacgtttg
     1321 gcaaaatggt gatggtttag ttccatattt gttataccgt acactgttaa tggcagattc
     1381 aaaatatgaa aaatcaactc cagatttagc taaagattgg aaaaaatctg atgatgaaaa
     1441 aacttatgaa tttacactta aagatggatt gaaatggtct gatggagaag ctttgacagc
     1501 ttccgatgtg gaattcagtg ttaaattagc attgaaagct tcagtaatta atggaatttt
     1561 cccttcaaca ttcacaaaaa ttgaaggagc taaagatttc aaagacgata aagcagataa
     1621 aatttctggt cttacagttg atggaaataa agtaacattt aaacttactg ctccagttgg
     1681 tgactttgag caaatgatga ctcaattctt tattcttcca aaacataaat tagagtctga
     1741 aaatcctctt gaattaaata atagctcatt ttggacagct cctgttacaa gcggtatgta
     1801 caaagtaaaa gaaattagtg caggtaattt cttagagtat gacaaaaatg aaaactatga
     1861 aaatgaaaaa ccaaaatttg ataaagtagt attcaactat atttcagatc cagttttagc
     1921 attgcaagat ggtaaatcat acttctattc aacaaacaaa cctcaagaaa ttagtcagtt
     1981 ggatgctgta tctactttaa gtaaaaaacc aattgatatc ctattctatc gctactttat
     2041 cgctaactta gcaggtgtcg aaggtaatgg agattccttg attgctaatc ctaaagttag
     2101 agaagctatt ctatatgcaa ttaatcgtga tgaattagct aaatctgtat ttagtggaat
     2161 tgcagatgtt aataatactg gtgttccttc aagcttagaa gctcatctga aatcagcaaa
     2221 taaatttgaa tataatccag aaaaagcaaa acaacttctt aaagaagcta aatacgataa
     2281 tagcagaaat ctaattttag cttattacta taaagatcaa gcctctcaag atttcatgca
     2341 agcagtaagt tatcaattga atgaggttgg aatcaagaac gaagttgtcc aaattacttc
     2401 tgatgcaaca acaggattgt tcaaaacacg taaatatgac ctagcttata aaggattatc
     2461 atcatttggt tatgaaactt ggtatggtga atatagttca acaaatacta actttaaaaa
     2521 tattacaaat ggcgaaacaa gttttgatga gttgagcaaa aaattgtctg aaacttctga
     2581 tgtaaaagaa agaaacaaaa ttttagcaag tct
//
LOCUS       DBJKQU010000087         2082 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.087, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000087 DBJKQU010000000
VERSION     DBJKQU010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2082
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.087"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            64..300
                     /gene="relB"
                     /locus_tag="ACSUUC_001970"
     CDS             64..300
                     /gene="relB"
                     /locus_tag="ACSUUC_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HHQ8055113.1"
                     /translation="MNNVVTTLISVQFSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKTISHEEMMRRYG"
     gene            293..1024
                     /locus_tag="ACSUUC_001971"
     CDS             293..1024
                     /locus_tag="ACSUUC_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HHQ8055114.1"
                     /translation="MAKIYAISDIHGYLDEFIDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEIYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLCYDTITQKYHFL"
     gene            complement(1135..1218)
                     /locus_tag="ACSUUC_001972"
     tRNA            complement(1135..1218)
                     /locus_tag="ACSUUC_001972"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1182..1184),aa:Leu,seq:caa)
     gene            complement(1228..1299)
                     /locus_tag="ACSUUC_001973"
     tRNA            complement(1228..1299)
                     /locus_tag="ACSUUC_001973"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1265..1267),aa:Gln,seq:ttg)
     gene            complement(1313..1385)
                     /locus_tag="ACSUUC_001974"
     tRNA            complement(1313..1385)
                     /locus_tag="ACSUUC_001974"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1350..1352),aa:His,seq:gtg)
     gene            complement(1400..1470)
                     /locus_tag="ACSUUC_001975"
     tRNA            complement(1400..1470)
                     /locus_tag="ACSUUC_001975"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1436..1438),aa:Trp,seq:cca)
     gene            complement(1475..1555)
                     /locus_tag="ACSUUC_001976"
     tRNA            complement(1475..1555)
                     /locus_tag="ACSUUC_001976"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1519..1521),aa:Tyr,seq:gta)
     gene            complement(1568..1640)
                     /locus_tag="ACSUUC_001977"
     tRNA            complement(1568..1640)
                     /locus_tag="ACSUUC_001977"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1605..1607),aa:Phe,seq:gaa)
     gene            complement(1644..1717)
                     /locus_tag="ACSUUC_001978"
     tRNA            complement(1644..1717)
                     /locus_tag="ACSUUC_001978"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1681..1683),aa:Met,seq:cat)
     gene            complement(1728..1817)
                     /locus_tag="ACSUUC_001979"
     tRNA            complement(1728..1817)
                     /locus_tag="ACSUUC_001979"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1779..1781),aa:Ser,seq:tga)
     gene            complement(1900..1973)
                     /locus_tag="ACSUUC_001980"
     tRNA            complement(1900..1973)
                     /locus_tag="ACSUUC_001980"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1937..1939),aa:Ile,seq:gat)
     gene            complement(2008..2078)
                     /locus_tag="ACSUUC_001981"
     tRNA            complement(2008..2078)
                     /locus_tag="ACSUUC_001981"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2044..2046),aa:Gly,seq:tcc)
BASE COUNT          688 a          418 c          404 g          572 t
ORIGIN      
        1 ttattgagaa acttttagac taggagtata atgtatctaa aataactatt aggtggctgt
       61 tatatgaata atgttgttac tacactaatt tctgttcaat ttagtcaaga gttaaattct
      121 ttattaaatg ctattgttga agaaaataat acaacaaaga ctgactttat tagacaagct
      181 gttatagaga aaattgaaga tatgtatgat attaaggtcg ctgatgaagc ttataaaaaa
      241 tgggttgaat gtggcaaaaa aactatctca catgaagaaa tgatgagacg ctatggctaa
      301 aatatacgca atatctgata tacatggata cttggatgaa ttcatagacg ctctcaataa
      361 agtaaattta aacgataaag ataatcgcct atttttacta ggagattatc ttgataatgg
      421 acttcaatct tttcaagtca tttccaaaat aatcgaactt gaggagattt atcctaatca
      481 aattattact cttctaggga accatgaaga atggttttat gattggttga ttttagataa
      541 gcctactgct tcagcatttc cagaaacaat aaaaagcttc ttctctccag aggaattgaa
      601 ctatattttt aaatcgaatg ctaacaactt tgaaacaggt gttagaaatg aaattaaaaa
      661 taatatcaaa ttcaacccat ttataaactg gtttaaaaag cgatataggg ataaacgcta
      721 ttatgaaact gatacccaaa tttttgttca tgcaggcatt gatgaagaag caggaatgct
      781 ttggaaagaa ctaacgagtt caaagatatt tacaaacaaa tttccaatta ccactggtag
      841 atttcataaa gctattattt cgggccatat tgcttcttgg gaagtagcta aagatagaag
      901 atacctaggt aagatttact atgatagtaa aagtcattac ttaattgatg gagatgtaac
      961 gaatagcaaa acaatacctg ttctttgcta tgatacaatt acccaaaaat atcactttct
     1021 ataactttta gtcatgtgct tttatatgaa attagtaatt attagtaaca attccaagaa
     1081 atttcttatg acataacaaa aagacaaggc ttagaaacct tgtcttttca actataccgg
     1141 cggccggggt cgaaccggca cgtccttgcg gacactggat tttgagtcca gcgcgtctgc
     1201 caattccgcc acgccggcaa atagtaactg gggtagctgg attcgaacca acgcatgagg
     1261 gagtcaaagt cccttgcctt accgcttggc tataccccaa taatataaaa taggcgagtg
     1321 atggggatcg aacccacgca tgccagagcc acaatctggt gtgttaacca cttcaccaca
     1381 cccgccataa ttctattaac acgggcagta ggaattgaac ccacactgaa ggttttggag
     1441 accttagttc tacctttaaa ctatgcccgt aaaatggaag gggagggatt cgaacccccg
     1501 aacccgaagg agcggattta cagtccgccg cgtttagcct cttcgctacc cttccaaaat
     1561 atataaatgg cgcgagacgg aatcgaaccg ccgacacatg gagcttcaat ccattgctct
     1621 accaactgag ctaccgagcc ttattgcggg agcaggattt gaacctacga ccttcgggtt
     1681 atgagcccga cgagctaccg tgctgctcca tcccgcgtta atataaaagg aggatgtggg
     1741 attcgaaccc acgcacgctt ttacacgcct gacggttttc aagaccgttc ccttcagccg
     1801 gacttgggta atcctccaaa atagtttata cgggaacaag cccgtgtcct cttagtgaac
     1861 agataatatt ccaatcccct agtaatggac taaacactat gggcacgagt ggactcgaac
     1921 caccgacctc acgcttatca ggcgtgcgct ctaaccacct gagctacgcg cccaagttaa
     1981 aaacttggta caaagaacaa agttcaaagc gggtgacgag aatcgaactc gcgacaacag
     2041 cttggaaggc tgtagtttta ccactaaact acacccgcta aa
//
LOCUS       DBJKQU010000088         2026 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.088, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000088 DBJKQU010000000
VERSION     DBJKQU010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2026
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.088"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(<1..1358)
                     /locus_tag="ACSUUC_001982"
     CDS             complement(<1..1358)
                     /locus_tag="ACSUUC_001982"
                     /inference="COORDINATES: protein motif:HMM:NF014051.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HHQ8055115.1"
                     /translation="MTKKSITRNFIFNTILTMSSFIFPLISFPYVSRVLMADGLGRVT
                     FASSIIDYALTFAMLGMPLYGVKVCAGYIKNKEKLSQTVRELLVINLLVGFLVMLLLA
                     TMVIIIPRFRQEWQLIIITSSTIPLNIIGIEWLYKALEDYSYISIRTLTFKILGFLLM
                     FLVVRTKDDYMVYAAITVLASHGSFILNFFRSRTFLLENISQRLNLKQHIKPLLILFF
                     LSVSWTIYKNTDVVMMGFLTSDTEIGYYSTALKIRSIVLSVVTSLGTVVLPRLVKYYK
                     EGKYNEAKKILNKSSSFIMLSSLYFIGYIVINAREIILFIAGRNYLGAIPTLQVSIFS
                     AIFVGYSIMYGTNILVSIGKENVTIQASIIGVVLNICLNFIMIPKFAALGAGIATSIG
                     EAVMVLYEIIYLGKDGWSYFERLNILKIIVVFIFSTFMLYIMKDFFVGYPLFIYIVIS
                     GV"
     gene            complement(1358..>2026)
                     /locus_tag="ACSUUC_001983"
     CDS             complement(1358..>2026)
                     /locus_tag="ACSUUC_001983"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HHQ8055116.1"
                     /translation="VIVLSQTWYDFFSNININAKIVIVENGVDTSFYVEKKKSITSNN
                     FLFLGRMGKRKGAYDLIDAMNQAVAINPNLHLTMAGDGELEDIRQKISNLNLTDHITI
                     YDWVNQRDKKILFQANQTLILPSYNEGLPMAILEAMASGLAIISTPVGGIPEIIHEDN
                     GWLIQPGDISQLSNIILEASYNPDVVSLMGSNNHKLVEEKYSFHSMHGKIKKIYNTLL
                     ETKK"
BASE COUNT          740 a          361 c          253 g          672 t
ORIGIN      
        1 ataacccctg aaattacaat ataaataaat aaaggatagc caacaaaaaa atctttcata
       61 atatataaca taaacgtact aaatataaat actacaataa tctttaaaat atttaatctt
      121 tcaaagtagc tccaaccatc ctttcccaag tatattattt catataatac cataacagct
      181 tctcctatag aagttgcaat acctgcccct agtgcagcaa atttgggtat cataataaaa
      241 ttcaaacaaa tatttaaaac aacaccaata atacttgcct gaatggttac attttcttta
      301 cctatagata ctaggatatt ggttccatac ataatagagt agccaacaaa tattgcacta
      361 aaaatagata cttgaagtgt cgggatagcc cctaagtaat tcctacccgc aataaaaaga
      421 ataatttctc tggcattaat tacaatatag ccaataaaat ataaagaact tagcataata
      481 aatgaagaac ttttgtttag tattttcttt gcttcattat actttccttc tttataatat
      541 ttgactaaac gaggtagtac aactgtccct aaagaagtta ctacactgag cactatagaa
      601 cgaattttta atgctgttga atagtaacca atttctgtat cactagttag aaatcccatc
      661 ataacgacat ctgtattctt ataaatagtc catgatacag ataaaaaaaa taaaattaat
      721 aacggcttta tatgttgctt taaattcaat ctttgagaga tattttctag taggaaagtt
      781 ctagatctaa aaaaattcaa aataaaagaa ccatgactag ctaaaactgt aattgccgca
      841 tataccatat agtcatcttt tgttcggacg actaaaaaca tcaaaaggaa acctaatatt
      901 ttaaaagtca atgttctaat tgaaatatac gaatagtctt ccaatgcttt gtataaccac
      961 tctattccta taatattgag aggaattgta gatgacgtga taataataag ctgccattcc
     1021 tgtctaaaac gaggaattat tattaccata gttgctaaaa gaagcatcac aagaaatcct
     1081 actaataaat taatgactaa caattctctg acagtctgac ttagcttctc cttattttta
     1141 atatatcctg cacagacttt aacaccatat aatggcatcc ctaacattgc aaatgttagg
     1201 gcataatcaa taattgaaga agcgaacgtt actcgtccca acccatctgc catcagaacc
     1261 cttgaaacat atgggaaact gatgagtgga aaaataaaac tggacatagt tagaattgta
     1321 ttgaaaataa aatttctagt aatagatttt ttagtcatta ttttttcgtt tctaatagag
     1381 tattataaat ttttttaatt ttaccatgca tactatgaaa actatacttc tcttcaacca
     1441 acttatgatt attgctcccc attaaactta caacatcggg attgtaactt gcttctaaaa
     1501 taatattaga taactgagaa atatcacccg gttgaattaa ccagccatta tcctcgtgta
     1561 taatttcagg tatgccacct acaggcgttg atatgattgc taatccagaa gccatagctt
     1621 ccaatattgc catcgggagc ccctcattat aagaaggcaa tatcaaagtc tgattagctt
     1681 gaaatagtat ttttttatct ctctgattaa cccaatcata tattgtaata tgatcagtca
     1741 aattcagatt tgatatcttt tgacgtatgt cttcaagttc tccatctcca gccattgtca
     1801 aatgcaaatt aggatttata gccactgctt gattcatggc atctattaaa tcataggctc
     1861 cttttctttt gcccatcctt cctaaaaaaa gaaagttgtt gcttgttata cttttctttt
     1921 tttctacata aaaagaagtg tctacaccat tttcaactat tacaattttt gcatttatat
     1981 taatatttga aaaaaaatca taccaagttt gggaaagtac aatcac
//
LOCUS       DBJKQU010000089         1986 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.089, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000089 DBJKQU010000000
VERSION     DBJKQU010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1986
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.089"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            33..1648
                     /locus_tag="ACSUUC_001984"
                     /pseudo
     CDS             33..1648
                     /locus_tag="ACSUUC_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT          704 a          238 c          360 g          684 t
ORIGIN      
        1 ttcaattaaa atttagaaag tgagaaacta ttgtgtatac tattataaaa tcaaatataa
       61 aaaaatttag tttattaacg atatttattg ttgctggtca attattgcta atttatgcag
      121 caactattaa tgctctggtg ttgaatgaat taattgcgat gaatttagag cggtttttga
      181 aattgtcaat ctaccaaatg attgtctggt gtgggataat attccttgac tgggtagtga
      241 aaaattatca ggttgaagtg atccaagagt ttaatctaga gattcgaaat agagttgcca
      301 cagacatctc taactctacc tatcaagaat ttcatagtaa atcatcagga acatatcttt
      361 cgtggctaaa taatgatgtt cagactttaa atgatcaggc ttttaaacaa ctttttttag
      421 taataaaagg aatttctggt actatatttg cagttgtgac tcttaatcac tatcattggt
      481 cattgactgt agccaccttg ttttcattaa tgattatgct acttgtacca aaaatctttg
      541 catcgaaaat gcgagaagtt agtctaaatt taactaacca aaatgaagct tttttaaaat
      601 ctagtgagac tatattgaat ggatttgatg tgttagcgtc cttgaatctt ttatatgtat
      661 tgcctaagaa aattaaagaa gcaggaattt tattaaagat ggttatacaa agaaagacaa
      721 ctgtagaaac gttagcaggc gctattagct tctttctcaa tatttttttt cagatatctc
      781 tcgttttttt aacaggctat cttgcaataa aaggaatagt gaaaattggt actattgaag
      841 caataggagc actaacaggt gttattttta cagcgctagg tgaattagga ggtcaattat
      901 cctctattat tggtacgaag cctatttttt taaaattgta ttcaattaat ccaattgagt
      961 caaataaaat gaatgatatc gaaccaaatg aggtgaatag agattttccg ttatatgaag
     1021 caaaaaatat ttgctataag tatggagata aagaaatatt aaaaaactta aatttttgtt
     1081 ttcaacgtaa tgaaaagtat ttaattttag gtgaaagtgg aagcgggaaa tctacattat
     1141 taaaattatt gaatggcttt ttgagagatt atagtggaga attgcgattc tgcggggatg
     1201 atataaaaaa acctcctatt taaatatggt ttcgaatgtt ctatatgtag atcaaaaagc
     1261 ttatttgttt gaaggtacga ttagagataa tattttattg gaagaaaatt atactgatga
     1321 agaaatacta cagtctttag agcaagttgg tttgagtgta aaagattttc ctaataacat
     1381 tttagattat tatgttggtg atgatgggag attactgtca ggagggcaga aacaaaaaat
     1441 tactttagct agagggctaa ttagaaataa gaaaatagta ttaattgacg agggaacttc
     1501 tgctatcgat aggagaactt cgttagcgat tgaacgtaag atattagata gagaggattt
     1561 gactgtcatt attgttaccc atgctccgca tccggaactt aaacaatatt ttactaagat
     1621 atatcaattt ccaaaggatt ttatttaaga atatagggga gggaaacatg agattctatt
     1681 gtgaagctta tgaggtaatt actgaagaga aaaaagtatc atttttttat gtagatgaga
     1741 aacccttaag gtatctgtta tttgactata tatttctact agttctagct aaaaaaaaat
     1801 atcccaatct tatgaactgc accccaaaag ttagatttat tctgtctaac ttttggggtg
     1861 cagttcattt tgcatagttt tggcattcat cctagatatc catataaaat gtctgagatt
     1921 gttgaaatgt ctaaaaaaat atcagatcta aacgataaaa aagaatttca caaaaagaac
     1981 tgtgag
//
LOCUS       DBJKQU010000090         1895 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.090, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000090 DBJKQU010000000
VERSION     DBJKQU010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1895
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.090"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(<1..755)
                     /locus_tag="ACSUUC_001985"
     CDS             complement(<1..755)
                     /locus_tag="ACSUUC_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055117.1"
                     /translation="MKDDQKYLLAGFYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFMFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSKVDLDIFYKVLPLLYKEKYT"
     gene            complement(912..1157)
                     /locus_tag="ACSUUC_001986"
     CDS             complement(912..1157)
                     /locus_tag="ACSUUC_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHQ8055118.1"
                     /translation="MDIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSTSPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            complement(1138..1500)
                     /locus_tag="ACSUUC_001987"
     CDS             complement(1138..1500)
                     /locus_tag="ACSUUC_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HHQ8055119.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGGVGCNWWNKRDNIAAAAVSGG
                     MSVYQTYAIKKLIANRGMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGA
                     IAYGLDIVDGKFDGYLWA"
BASE COUNT          696 a          347 c          239 g          613 t
ORIGIN      
        1 gtatattttt ctttataaag caaaggtaaa actttataaa aaatatctaa gtcaacctta
       61 ctctgattct gaagcaagta ggagtcaagc aaattttcaa aaatagctaa caatatgatt
      121 ggtgtaaggt ttttgtattc acatgtcaag tattccgagt atcgtgcaga tgatatttct
      181 tttacataac tttttgaaag caagattttt tcaaattcat catctattat taatcttcta
      241 tttccaatcc aaacggtatt accacccaaa taagattgtg caaatagcaa tatgtaagaa
      301 aacatgaacg taaatactga aagaggtaga attctatgcg taaaaaaata gacgataatg
      361 gtagccagga gtaaagatat ctctcgtgac aatcgaattc ttttcagcat cttttttaac
      421 agtccgtaag gttgtccttg gcaatattct tgaactaaat taatcggaat gacatctctc
      481 accatttctg gaaagtagag taagtttata ggttgaaatc tccagctccc atcataagta
      541 aatggatata gaaccaaata cttaaaagat ttttttctta taaacttaat tatcacaata
      601 tgaatgactg ttccaatgaa gtatattaaa tataaaagta aaaccgccat caatatactt
      661 acaaaaatcc ccttggaatc aatcaatgga aaataaaata ttgcaactag aagcgaataa
      721 aatcccgcta ataaatattt ctgatcatct ttcattcaaa acaccatatt atttactaag
      781 aatacatcaa tacaatagag caactctgta agtcaatatt tgataaagca aagctttaaa
      841 cccttcccca gacgttagct tttattcaac ccactacagt tgacaaggag cccaaattat
      901 tgataaaaac tttagtcatc atcgtctcta taaaaatatt ttctatacac tcttgataat
      961 accaaaatta atgccaatat cataccaaga gctataataa tagaatttat tagatttatt
     1021 ttagtatatc caatcactag tccaataatt ggactggtag acatgcttag atataataaa
     1081 aataacaaaa aatgaatttc accaattcct gcaaaaaaat gtttcatagc tatagtttta
     1141 cgcccataaa tatccatcaa atttaccgtc tacgatatct aaaccatatg caatggctcc
     1201 tcctaatgag aagacttcag caacagtagc cgcaatatta agagcattag taatagttgc
     1261 catactaact ccaccaatat atcttgttat agcacttcta acgactcggc tcatcatacc
     1321 acgattagca attaactttt taatggcata tgtctggtat actgacatcc ctccagaaac
     1381 tgcagctgca gcaatattat cacgtttgtt ccaccagtta caaccaacac cacccccatc
     1441 aagatacatc atctcttctt gctcaagaac aacataatta tttggtaata cgagttccat
     1501 ttattttctc cttttttatt aagcatagtt aggatagttt cctaacaagt gatcgttgac
     1561 tttgtttata gcacttagtt acctagataa gatatccttt agcttgcttc caaaatttaa
     1621 gtctgcacct ataatatgag ttcatattag tactgctaaa tcctatctat agtaatgtca
     1681 aacacctaaa taaagtcatc tctccgattc attcaagaaa tgaagaaagg caaaaaatct
     1741 ttaaaataag aaaaatgcat attatcaggt gttcaaaaat attgatgata tacgttatat
     1801 agatagaaag atttactcaa tctcattttc aaattgagtt ttttcccaac ctcgttttta
     1861 atttatatct tcaatagaat ctaatgaccg agcta
//
LOCUS       DBJKQU010000091         1884 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.091, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000091 DBJKQU010000000
VERSION     DBJKQU010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1884
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.091"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            complement(<1..198)
                     /locus_tag="ACSUUC_001988"
     CDS             complement(<1..198)
                     /locus_tag="ACSUUC_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HHQ8055120.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNHQVKGTKPRKVDRDRLK"
     gene            280..731
                     /locus_tag="ACSUUC_001989"
                     /pseudo
     CDS             280..731
                     /locus_tag="ACSUUC_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            896..1195
                     /locus_tag="ACSUUC_001990"
     CDS             896..1195
                     /locus_tag="ACSUUC_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HHQ8055121.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1456..1779
                     /gene="tnpB"
                     /locus_tag="ACSUUC_001991"
     CDS             1456..1779
                     /gene="tnpB"
                     /locus_tag="ACSUUC_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HHQ8055122.1"
                     /translation="MMILLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKYRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
BASE COUNT          617 a          367 c          327 g          573 t
ORIGIN      
        1 tttaagtcta tctctatcaa cttttcttgg ttttgttcct tttacttggt ggtttagctc
       61 tcctgttttc tcttttagct ttaaccagcc ataaatggta ttacgtgaga tttggaaaac
      121 gtgtgatgct tctgttatac tacctgttcg ctcacaataa gagagaactt ttttacgaaa
      181 atctattgaa tatgccataa gaagattata ccacattgtg tactattttt ggttcatttc
      241 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
      301 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      361 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      421 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      481 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      541 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      601 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      661 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      721 agattggcta atactcttcg aaaataaaat tcaaaccacg tcagcgtcgc cttaccgtac
      781 tcaagtatag cctgcggcta tcttcctagt ttgctctttg attttcattg agtataaatc
      841 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      901 gcttatcaat acgacaaact cacactcgca actggtaaaa agtcagctag aaagtaccga
      961 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
     1021 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
     1081 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgttg atgaagccaa
     1141 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
     1201 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1261 taacaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1321 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1381 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcagag
     1441 gaaaggtatt gtactatgat gattctacta agtgatttag gtcaagttca ccttgtttgt
     1501 ggcaagacag atatgaggca gggaatagac tcattagcct atgtagttaa aacccacttt
     1561 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa ataccgcttt
     1621 aaagccctct actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacggc
     1681 agactgactt ggcccagtac agaaaaggat gtcaaagctc tcacatctga acaagtagac
     1741 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1801 cacctctact tctaaaacat tgttagaaat caatttgact gtcctgatcg atttgtactg
     1861 ttcttatttc attttactat agaa
//
LOCUS       DBJKQU010000092         1645 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.092, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000092 DBJKQU010000000
VERSION     DBJKQU010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.092"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..1473
                     /locus_tag="ACSUUC_001992"
     rRNA            <1..1473
                     /locus_tag="ACSUUC_001992"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            1550..>1645
                     /gene="rrf"
                     /locus_tag="ACSUUC_001993"
     rRNA            1550..>1645
                     /gene="rrf"
                     /locus_tag="ACSUUC_001993"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          454 a          340 c          479 g          372 t
ORIGIN      
        1 actagagtat gtagtgatgg agggacgcag taggctaact aaagcagacg attggaagag
       61 tctgtctaag cagtgaggtg tgaattgagt caaatgctta attctataac attgagctgt
      121 gatggggagc gaagtttagt agcgaagtta gtgacgtcac actgccaaga aaagcttcta
      181 gcgtttaaac atactctacc cgtaccgcaa accgacacag gtagtcgagg cgagtagcct
      241 caggtgagcg agagaactct cgttaaggaa ctcggcaaaa tgaccccgta acttcgggag
      301 aaggggtgct gacttaaagt cagccgcagt gaataggccc aagcaactgt ttatcaaaaa
      361 cacagctctc tgctaaatcg taagatgatg tatagggggt gacgcctgcc cggtgctgga
      421 aggttaagag gagtgcttag cgtaagcgaa ggtatgaatt gaagccccag taaacggcgg
      481 ccgtaactat aacggtccta aggtagcgaa attccttgtc gggtaagttc cgacccgcac
      541 gaaaggcgta atgatttggg cactgtctca acgagagact cggtgaaatt ttagtacctg
      601 tgaagatgca ggttacccgc gacaggacgg aaagacccca tggagcttta ctgcagtttg
      661 atattgagtg tctgtaccac atgtacagga taggtaggag tctaagagat cgggacgcca
      721 gtttcgaagg agacgctgtt gggatactac ccttgtgtta tggccactct aacccagata
      781 ggtgatccct atcggagaca gtgtctgacg ggcagtttga ctggggcggt cgcctcctaa
      841 aaggtaacgg aggcgcccaa aggttccctc agaatggttg gaaatcattc gcagagtgta
      901 aaggtataag ggagcttgac tgcgagagct acaactcgag cagggacgaa agtcgggctt
      961 agtgatccgg tggttccgta tggaagggcc atcgctcaac ggataaaagc taccctgggg
     1021 ataacaggct tatctccccc aagagttcac atcgacgggg aggtttggca cctcgatgtc
     1081 ggctcgtcgc atcctggggc tgtagtcggt cccaagggtt gggctgttcg cccattaaag
     1141 cggcacgcga gctgggttca gaacgtcgtg agacagttcg gtccctatcc gtcgcgggcg
     1201 taggaaattt gagaggatct gctcctagta cgagaggacc agagtggact taccgctggt
     1261 gtaccagttg tcttgccaaa ggcatcgctg ggtagctatg tagggaaggg ataaacgctg
     1321 aaagcatcta agtgtgaaac ccacctcaag atgagatttc ccatgattat atatcagtaa
     1381 gagccctgag agatgatcag gtagataggt tagaagtgga agtgtggcga cacatgtagc
     1441 ggactaatac taatagctcg aggacttatc caaagtaact gagaatatga aagcgaacgg
     1501 ttttcttaaa ttgaatagat attcaatttt gagtaggtat tactcagagt taagtgacga
     1561 tagcctagga gatacacctg tacccatgcc gaacacagaa gttaagccct agaacgccgg
     1621 aagtagttgg gggttgcccc ctgtg
//
LOCUS       DBJKQU010000093         1481 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.093, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000093 DBJKQU010000000
VERSION     DBJKQU010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.093"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            73..>1481
                     /gene="pcpA"
                     /locus_tag="ACSUUC_001994"
     CDS             73..>1481
                     /gene="pcpA"
                     /locus_tag="ACSUUC_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HHQ8055123.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKGTKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKG"
BASE COUNT          582 a          201 c          238 g          460 t
ORIGIN      
        1 actttttata acaacggcta gcaaagttat aattttatat ctattagaaa ataaatatgt
       61 aaggaaattt aaatgaaaaa aactacaata ttatcattaa ctacagctgc agttatttta
      121 gcagcatatg tccctaatga accaatccta gcagatactc ctagttcgga agtaatcaaa
      181 gagactaaag ttggaagtat tattcaacaa aataatatca aatataaggt tctaactgta
      241 gaaggtaaca taggaactgt tcaagtgggt aatggagtta ctcctgtaga gtttgaagct
      301 ggtcaagatg gaaaaccatt cacgattcct acaaaaatca cagtaggtga taaagtattt
      361 accgttactg aagtagctag tcaagctttt agttattatc cagatgaaac aggtagaatt
      421 gtctactatc ctagctctat tactatccca tcaagcataa aaaaaataca aaaaaaaggc
      481 ttccatggaa gtaaagctaa aactattatt tttgacaaag gtagtcagct ggagaaaatt
      541 gaagatagag cttttgattt ttctgaatta gaagagattg aattgcctgc atctctagaa
      601 tatattggaa caagtgcatt ttcttttagt caaaaattga aaaagctaac cttttcctca
      661 agttcaaaat tagaattaat atcacatgag gcttttgcta atttatcaaa tttagagaaa
      721 ctaacattac caaaatcggt taaaacatta ggaagtaatc tatttagact cactactagc
      781 ttaaaacatg ttgatgttga agaaggaaat gaatcgtttg cctcagttga tggtgttttg
      841 ttttcaaaag ataaaaccca attaatttat tatccaagtc aaaaaaatga cgaaagttat
      901 aaaacgccta aggggacaaa agaacttgca tcatattcgt ttaataaaaa ttcttacttg
      961 aaaaaactcg aattgaatga aggtttagaa aaaattggta cttttgcatt tgcagatgcg
     1021 attaaacttg aagaaattag cttaccaaat agtttagaaa ctattgaacg tttagccttt
     1081 tacggtaatt tagaattaaa agaacttata ttaccagata atgttaaaaa ttttggtaaa
     1141 cacgttatga acggtttacc aaaattaaaa agtttaacaa ttggtaataa tatcaactca
     1201 ttgccgtcct tcttcctaag tggcgtctta gattcattaa aggaaattca tattaagaat
     1261 aaaagtacag agttttctgt gaaaaaagat acatttgcaa ttcctgaaac tgttaagttc
     1321 tatgtaacat cagaacatat aaaagatgtt cttaaatcaa atttatctac tagtaatgat
     1381 atcattgttg aaaaagtaga taatataaaa caagaaactg atgtagctaa acctaaaaag
     1441 aattctaatc agggagtagt tggttgggtt aaagacaaag g
//
LOCUS       DBJKQU010000094         1222 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.094, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000094 DBJKQU010000000
VERSION     DBJKQU010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1222
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.094"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..71
                     /locus_tag="ACSUUC_001995"
     CDS             <1..71
                     /locus_tag="ACSUUC_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HHQ8055124.1"
                     /translation="IMEILEERIDDNVEKSSKDEIT"
     gene            381..>1222
                     /gene="mobQ"
                     /locus_tag="ACSUUC_001996"
     CDS             381..>1222
                     /gene="mobQ"
                     /locus_tag="ACSUUC_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="HHQ8055125.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIG"
BASE COUNT          565 a          163 c          219 g          275 t
ORIGIN      
        1 acataatgga aattttagaa gaaagaatag atgataatgt agaaaaatca tctaaagatg
       61 aaataacata attgtccctt ggttacaagg gcgcaattat acaccctaaa gggtgcttgc
      121 gtcctgcgga gtcaaaccct tgcagggagt aacaaccatt cgctttttaa aagtcaaggg
      181 taaataaact cgctaaggct cgcccttgac ttttaaaatt tgaaatgaaa gtaacaatta
      241 agccgacata ctgaaacaac aaaaattaat tcagtagtcg gcttttttaa ttctatcatt
      301 tcaaaacgct cattcacaaa gaggatataa aaaaactatt aagcctccac ctaaaacaac
      361 aaagaaagga agtgataaaa atggcagaca gttttcattt ttcagtaaac ataatatcaa
      421 gaggaaaagg caaaagtgca gtagcaagtg cagcatatat aagtggagaa aaaataaaaa
      481 atgaatggga cggagtaacc catgactata caagaaaaga aaaaatatta gtaaaaaata
      541 taatattgcc tgatcatata ccaaaagaat ttaatgatag gtctacctta tggaataaag
      601 tagaaatggc agaaaaaaat tctaatgcac aactagcaag acaattcata ataggactac
      661 caaaagagtt atctttaagt gaaaataaaa acctggttga aagatatata aaagaaaatt
      721 taacatcaca aggaatgata gtagattatg caattcatga tgagagtcaa gataaaaatg
      781 gaaatatcca ttgtcatata atgaccataa tgcgaccaat aaacgaaaaa ggagagttct
      841 tagccaagtc aaaaaaagaa tatatcctag atgaaaaagg agaaaaagta ttaaacaaaa
      901 atggaaaacc aaagacaaga aaagtagaac taacaacctg gaacgataca ggcaatgtag
      961 aaaaatggag agaaaatttt tcagatcttt gtaacaaata tttagaaaga gcaggagcag
     1021 aaaaaagagt agaccatagg agttttaaaa gacaaaattc agattatcta ccgacaatcc
     1081 atttaggatc agcagcaagt gcaatggaaa gaaagggaat agaaactgac aagggaaact
     1141 ataatagaga aataagaaaa tataatcaac ttgtaaaaac aataaaagaa gagataaaaa
     1201 cattaaaggg ttggatagga aa
//
LOCUS       DBJKQU010000095         1182 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.095, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000095 DBJKQU010000000
VERSION     DBJKQU010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1182
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.095"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..99
                     /locus_tag="ACSUUC_001997"
     CDS             <1..99
                     /locus_tag="ACSUUC_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HHQ8055126.1"
                     /translation="QVDETDEVDGMRFSTFSTNRCGNWSAFSWENC"
     gene            893..1111
                     /locus_tag="ACSUUC_001998"
                     /pseudo
     CDS             893..1111
                     /locus_tag="ACSUUC_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          383 a          159 c          240 g          400 t
ORIGIN      
        1 caagttgacg aaacagatga agttgatgga atgcgattta gtacattcag tacaaaccgt
       61 tgcggtaact ggagtgcttt tagttgggaa aattgttaat tcatttaaat tgtaaacttt
      121 agagattctc tggagttatg gatgtcgttc caatatgtgc acgttggaat gttagtgctt
      181 atatgggggg aacagaatcc tctcttgatt gaagacaagc tagtcattag gctggtttgt
      241 ctttttgtca actgtagtgg gttgatataa tagtattagt gagtgggata aaagtttcat
      301 ttagtttatt cagtacaaat ttaacgggtc aagatttata tactagtggt gtttttgggg
      361 ctgagagaag tatcttgatt ttatgtgtgg tttttatact tacagttgtt ctgctccaaa
      421 gagcttgtag agaagaatta gctcataaag gagattgatt attttgatat caaaaaaatg
      481 cacaggataa cctgatgcat ttttttagcg acaatgcttg ctacttcctt ctgtcgaatt
      541 tagacaattt taaataaaag aatgaaatat tccctactgt atttttagac gaagaacgtt
      601 agttaataat actcaaattt atttcaaact ctttgattag tatgaattta gctctacaga
      661 aaaataaaaa atgtgataaa aatttcaact actcttatct ataataaagc tacctgttct
      721 ttgaaaattg aatccactcc gtcttgatta gcgtgcctgt gtaagtaggg actgagagta
      781 tttccctgtg aagggcaact ggcacaagac gtgtgtgaga attttctaac agacacggag
      841 tttatcgttt ccagactcaa acgatgcgac aaactagata aaggagttaa tcatgaaggt
      901 agtaaacttg tatgatttga aacaaatggg aaataaaggt ggttgtacca tccaattgat
      961 tcatcacttt ccttttggta tgggcttagg acatctcaaa aaagactaca ttgaatttaa
     1021 acgtgttggt atctttgatg ggaaagcagt agaagttact cttcgagaac cttattcgag
     1081 agatctactt caggttgtca agtcaataaa gtaactgaca ccatgagtat aattattaga
     1141 aacgtggaat cttattaaat tttataataa atatattaaa tg
//
LOCUS       DBJKQU010000096         1029 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.096, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000096 DBJKQU010000000
VERSION     DBJKQU010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1029
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.096"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..759
                     /locus_tag="ACSUUC_001999"
     CDS             <1..759
                     /locus_tag="ACSUUC_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="HHQ8055127.1"
                     /translation="NSTINGIIFIREDELPDAINQVDFIITCFSNHIETDNFINEFLL
                     NIQSLRKTIVIDFTTSRIDCVEKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHI
                     DEGVNYNKKELMELLKLISKKIYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYD
                     FSPKSLEVANTIVCNDGWMSLVCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFH
                     DEVKEINYLLQQYRDCLVTDSGKDYTVIGKYDNL"
     gene            746..>1029
                     /locus_tag="ACSUUC_002000"
     CDS             746..>1029
                     /locus_tag="ACSUUC_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HHQ8055128.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSR"
BASE COUNT          390 a          110 c          183 g          346 t
ORIGIN      
        1 aattcaacaa taaatggaat aatatttatt agagaagatg aattacctga tgctataaat
       61 caggttgatt ttataatcac ttgttttagt aatcatattg aaacggataa tttcattaat
      121 gagtttttat taaatataca atcacttcgt aaaaccatag taattgattt tacaacctcc
      181 aggattgatt gcgttgaaaa atttaaaaaa actgttgaaa ttaaaggggg atactatata
      241 gaggctcctt tcacaggagg taagttagga agtaatagtg gtcaactatc aattttttta
      301 catattgatg aaggtgtaaa ctataataaa aaggagttaa tggaattatt aaaattaatt
      361 tcaaaaaaaa tatacttttt tgaaaagagt acggaaccaa caaaattcaa gttaatttat
      421 aactcgtggg gagcgtattt gctttactct attaagctat tcaacccttt acagtatgat
      481 ttttcaccaa agtctctaga ggtagcgaat acaatcgtat gtaatgatgg ttggatgagt
      541 ttagtatgca actccaaatt agaacagatc aatgatcaag attttgatga catacacttt
      601 agagtagaat atatggtaaa agatttagaa tatgctaatt tttcagtctt tcatgatgaa
      661 gtgaaagaaa taaattattt attacagcaa tatagggatt gcttagtaac tgatagtgga
      721 aaagattata cggtaatagg aaagtatgat aacttatagg aatgacttgc tgtctaaaga
      781 attagatata ctaatttcat tttttaaaaa atgcgaggta ggaaaaattt cactcgttat
      841 tactggttcc ttggcaagag gtaatccaag aatcaaggat gggaaattag aatcggatat
      901 tgatattcta gttatagtag acagtattca gcaattaatt agtataaaaa agactttaga
      961 gggaaggttt cactttgtac ataaaatttc tttgattttt tgtttgaagg aaagaataaa
     1021 tcgaagtcg
//
LOCUS       DBJKQU010000097          986 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.097, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000097 DBJKQU010000000
VERSION     DBJKQU010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.097"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            135..886
                     /locus_tag="ACSUUC_002001"
                     /pseudo
     CDS             135..886
                     /locus_tag="ACSUUC_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000225 -
                     N-acetylglucosaminylphosphatidylinositol deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0006506 - GPI anchor biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
     gene            899..>986
                     /locus_tag="ACSUUC_002002"
     CDS             899..>986
                     /locus_tag="ACSUUC_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HHQ8055129.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYD"
BASE COUNT          343 a          108 c          191 g          344 t
ORIGIN      
        1 aggatattga aatatttata tatatgttta tttaacgaaa tattcattat taagaataag
       61 gtgaattttt ttgatgatgt ggaatttaat cagacactta gtgagttttt agataaattg
      121 tagagggaat ggttatgagt aacaatacta agtatatctt tttatctcca catttagatg
      181 acgcaatttt ttcctgtggt gattatattt caaaattaac ttcagaagga gaaattgtac
      241 ttgttattac tatattttct ggttaccctt tgagccaaca gctacagccc tctgctaagc
      301 aatttcataa gttgtgtaac cttgggaaat atccgattga agaaaggaag aaagaagaca
      361 ggttagcttg tgaacgtcta caatgtgatt ttagacactt atcgtactat gaatgtctct
      421 ataggaaaga tagaaatggc aattttctat accgtcatat ctatagtgaa ttaaaaaatg
      481 aggacacatt aaagaatgat atcataaaag agctgttaat gcatttagac gacaaatgtg
      541 tcgtatattg tccgctttca cttggtgacc atgttgatca tgtttttgtg aatagtattg
      601 gaagggcgct tgaatttatg cgttataaag taatatatta tgaggacttc caatatgtaa
      661 gtgatagtag tatggttggt tatatgggaa aaactaaaga attaaaaatg tatcaagagg
      721 aacttgataa aaaaaacatt atattgatag aatatcatca atatcgtgct ataaatctca
      781 gattttgata atctggaaat cagttgaaaa acttttaaac aatattaaag agttgtattt
      841 aaggaatggg gcagcttatt ctattagatt ttggattaag aaataaggaa gtagttttat
      901 gaatatagca gtaattggtt tggggcatgt tgggctggcc tacgcgttac tatttgcatc
      961 taaatataaa gttgttgcat atgata
//
LOCUS       DBJKQU010000098          956 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.098, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000098 DBJKQU010000000
VERSION     DBJKQU010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..956
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.098"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..>956
                     /gene="phtD"
                     /locus_tag="ACSUUC_002003"
     CDS             <1..>956
                     /gene="phtD"
                     /locus_tag="ACSUUC_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HHQ8055130.1"
                     /translation="PAPSNPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETA
                     AGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKGRQVDFEA
                     LDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKY
                     TTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPS
                     TGHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNI
                     KFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGF"
BASE COUNT          308 a          187 c          215 g          246 t
ORIGIN      
        1 accagctcca agcaatccaa ttgatgagaa attggtcaaa gaagctgttc gaaaagtagg
       61 cgatggttat gtctttgagg agaatggagt ttctcgttat atcccagcca aggatctttc
      121 agcagaaaca gcagcaggca ttgatagcaa actggccaag caggaaagtt tatctcataa
      181 gctaggagct aagaaaactg acctcccatc tagtgatcga gaattttaca ataaggctta
      241 tgacttacta gcaagaattc accaagattt acttgataat aaaggtcgac aagttgattt
      301 tgaggctttg gataacctgt tggaacgact caaggatgtc tcaagtgata aagtcaagtt
      361 agtggatgat attcttgcct tcttagctcc gattcgtcat ccagaacgtt taggaaaacc
      421 aaatgcgcaa attacctaca ctgatgatga gattcaagta gccaagttgg caggcaagta
      481 cacaacagaa gacggttata tctttgatcc tcgtgatata accagtgatg agggggatgc
      541 ctatgtaact ccacatatga cccatagcca ctggattaaa aaagatagtt tgtctgaagc
      601 tgagagagcg gcagcccagg cttatgctaa agagaaaggt ttgacccctc cttcgacagg
      661 ccatcaggat tcaggaaata ctgaggcaaa aggagcagaa gctatctaca accgcgtgaa
      721 agcagctaag aaggtgccac ttgatcgtat gccttacaat cttcaatata ctgtagaagt
      781 caaaaacggt agtttaatca tacctcatta tgaccattac cataacatca aatttgagtg
      841 gtttgacgaa ggcctttatg aggcacctaa ggggtatagt cttgaggatc ttttggcgac
      901 tgtcaagtac tatgtcgaac atccaaacga acgtccgcat tcagataatg gttttg
//
LOCUS       DBJKQU010000099          792 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.099, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000099 DBJKQU010000000
VERSION     DBJKQU010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..792
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.099"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            1..792
                     /locus_tag="ACSUUC_002004"
                     /pseudo
     CDS             1..792
                     /locus_tag="ACSUUC_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family A protein"
BASE COUNT          306 a           77 c          145 g          264 t
ORIGIN      
        1 gaagttataa ttattgatga taattatagt aatgtaaatt taagaaataa aattatccat
       61 caatttggct ataccaatca tagaattaag ttaattttaa gtaatgaaga tttaggtgca
      121 actaatgcca gaaacatagg tatcaaaaat tctagaggta agtatatatc atttttagac
      181 gatgatgatg aatatatgcc agatcgaatt ttaaagttga tggcttgttt taaaaagagt
      241 agaatgaaga atttagcttt agtttatagt tatggaataa taatttatcc aaatggtaca
      301 cgagaagagg agaagaccga ttttgttgga aatcccttgt ttgttcaaat ggttcacaat
      361 atagcaggta cgtcattttg gttgtgtaaa aaagaggtgc tagaattaat taatggtttt
      421 gagaaaatag attcacatca ggacggtgtt gttttattaa aactacttgc tcaaggatac
      481 caaattgata tagtgcgaga attcttggtg aattactacg ctcacagtaa agaaaacggt
      541 atcactggag tgacacaaaa aaacaattaa tgcagatgaa gaatattata attactgtag
      601 gaaatatttt aatttattga gtttcaacga gagaatattg gttacaaaga aatattattc
      661 tttaaacata aagcggttac tattaatagg agacaaatgc aaggctttaa aagtaatcaa
      721 gaaggcaaga gaagaaaaaa tttttaacga atttcttttt tgaaatatat gttattatat
      781 cattttggtt tt
//
LOCUS       DBJKQU010000100          698 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.100, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000100 DBJKQU010000000
VERSION     DBJKQU010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..698
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.100"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            1..503
                     /locus_tag="ACSUUC_002005"
                     /pseudo
     CDS             1..503
                     /locus_tag="ACSUUC_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(622..695)
                     /locus_tag="ACSUUC_002006"
     tRNA            complement(622..695)
                     /locus_tag="ACSUUC_002006"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(659..661),aa:Asn,seq:gtt)
BASE COUNT          237 a          154 c          106 g          201 t
ORIGIN      
        1 tccggggagt gactgtttca atcgggagat ggagatgagc tttattgctc aagactttga
       61 taagctcaat atcataactg ttcttgagag cagaacacaa gccatcatcc gaaatcccat
      121 gaatacaagg ctatcaagcg atactgaaag ctcattcaac aagatagtca gaaactgagt
      181 gataaacgat tttatcgccc tacttttcgt atgcacttga ctaataaaga aattctagat
      241 aaacttttga gctattccga agacttgaaa caccactata atctctatca gctcttgctt
      301 ttccacctct ttttcagact ctgtttaaaa ccttcctcaa agataaagaa aaaatcgtca
      361 acggccttca attaccttat tccaacgcca aactggaagc caccaataat ctcatcaaac
      421 ttatcaagta caatgccttt ggttttagga actttgaaaa cttcaaaaaa gaaaggacga
      481 aatttgtcct ttctcaagct tagcttttct tcaacccact acagttgaca aagagccact
      541 atttttggtt cattttacta taacacgaaa tagattatta ttacataata aaaaagaggt
      601 ctaaacctct taactaaatt actccgccag taggactcga acctacgaca tcatgattaa
      661 cagtcatgcg ctactaccaa ctgagctatg gcggatta
//
LOCUS       DBJKQU010000101          642 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.101, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000101 DBJKQU010000000
VERSION     DBJKQU010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.101"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            105..584
                     /locus_tag="ACSUUC_002007"
     CDS             105..584
                     /locus_tag="ACSUUC_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HHQ8055131.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          242 a           81 c          149 g          170 t
ORIGIN      
        1 gtctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattgtcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagatc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgcgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctagtaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa ag
//
LOCUS       DBJKQU010000102          614 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.102, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000102 DBJKQU010000000
VERSION     DBJKQU010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.102"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            <1..>614
                     /locus_tag="ACSUUC_002008"
     CDS             <1..>614
                     /locus_tag="ACSUUC_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHQ8055132.1"
                     /translation="PYLKEGGEYQIKNLSYKFTDDECLSLKDISFKLGKIYGIIGSNG
                     RGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVMQDVNHQLFTDEVFNELR
                     LGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAIASVMCKNSPFVFFDEPS
                     SGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADEIFE"
BASE COUNT          237 a           71 c          117 g          189 t
ORIGIN      
        1 ccttatttaa aagaaggtgg agagtatcag ataaaaaatc ttagctacaa atttactgat
       61 gatgagtgtt taagcttaaa agatatttcg ttcaagcttg ggaaaattta tggcataata
      121 ggatccaacg gacgaggaaa atcaacgctt ttaagatgtt taataggtct tgagaaaaaa
      181 tcaaaagaag aaatttattt taagggagag aagctatcta aaaaagaaag actcaaaaac
      241 tcttcacttg ttatgcaaga tgtaaatcat caattattca cagatgaagt attcaacgag
      301 cttagattag gagtaaagaa ttttgatgaa gaaaaggcga aaatcatttt aaaagattta
      361 ggcctggacg aatttattga aaggcatccg atgagtttat caggagggca aaagcaaagg
      421 cttgcaatag catctgttat gtgcaagaat tctccatttg tcttttttga cgaaccttca
      481 agtggtatgg attattccaa tatgataaaa atatctgaac tgattaataa gtataaaacc
      541 atggataaaa taatttttat tgtttcccat gatatagaat ttttaaatga agtggcagat
      601 gaaatttttg aatt
//
LOCUS       DBJKQU010000103          534 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.104, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000103 DBJKQU010000000
VERSION     DBJKQU010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.104"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
     gene            122..304
                     /locus_tag="ACSUUC_002009"
     CDS             122..304
                     /locus_tag="ACSUUC_002009"
                     /inference="COORDINATES: protein motif:HMM:NF016232.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AlbA family DNA-binding domain-containing
                     protein"
                     /protein_id="HHQ8055133.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            249..>534
                     /locus_tag="ACSUUC_002010"
     CDS             249..>534
                     /locus_tag="ACSUUC_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HHQ8055134.1"
                     /translation="MKKTLTPTKESIDSLRNYEASKQLTDTRFKRLVGVQRTTFKEML
                     AVLKTAYQLKHAKGGRKPKLSLEDLLMATLQYVREYRTYEEIAAVFCIHES"
BASE COUNT          213 a           92 c           93 g          136 t
ORIGIN      
        1 gaaattaaag tgggttaaaa aagaaattaa ctgagtaaaa actctcgaaa ttcaattcgc
       61 tatattatca ctcaacttga acaaatacca gaaccacaaa aaacagatgt aaaggaaaaa
      121 tatggactta aaatttgaag gggttgattt agaatacaaa aaagctaaaa acaatcttcc
      181 agagtctttc tgggaaacct actcagcatt tgcaaataca aatggcggga aaataattct
      241 cgggatagat gaaaaaaaca ttgacaccta ccaaagagtc aatagactcc ctgcgaaatt
      301 atgaagcaag taaacaatta actgatacac gatttaagcg tcttgttggt gttcagcgta
      361 ccacttttaa agagatgtta gctgtattaa aaacagctta tcaacttaaa cacgcaaaag
      421 gtggacgaaa acctaaatta agtctagaag accttcttat ggccactctt caatatgtgc
      481 gagaataccg cacttatgaa gaaattgcgg ctgttttttg tatccacgaa agca
//
LOCUS       DBJKQU010000104          430 bp    DNA     linear   BCT 21-JUL-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SPRLISCIII0696-20 isolate
            SPRLISCIII0696-20 SAMEA116299307-rid26930293.denovo.105, whole
            genome shotgun sequence.
ACCESSION   DBJKQU010000104 DBJKQU010000000
VERSION     DBJKQU010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA116299307
            Sequence Read Archive: ERR13906114
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JUL-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002838783.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002838783.1
            Genome Coverage       :: 856x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/20/2025 03:51:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 2,010
            CDSs (total)                      :: 1,963
            Genes (coding)                    :: 1,816
            CDSs (with protein)               :: 1,816
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 70 of 147
            Pseudo Genes (incomplete)         :: 66 of 147
            Pseudo Genes (internal stop)      :: 48 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA116299307-rid26930293.denovo.105"
                     /strain="SPRLISCIII0696-20"
                     /serovar="8"
                     /isolate="SPRLISCIII0696-20"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="Spain"
                     /lat_lon="40.45939023 N 3.86502536 W"
                     /collection_date="2020"
BASE COUNT          142 a           64 c           63 g          161 t
ORIGIN      
        1 tccaatttat ttgtttatat cttatttcag tttactatac tagcttatta ttctagtgaa
       61 aaattgaatg agccactatt tatttaatat gtatgatgag ggaatgactc aaaaacttct
      121 tgtcgatata agaatatctg agatagtatt ttaaaacgaa aggactataa aagctcattt
      181 ccttcgcact tattttataa agatctatca ttatactctt tagaaatcaa aaagcaacac
      241 accttgtcat cgttttatcg taaatctgtt aatgaggggg ctagtcttat ctgcaatctc
      301 aaatcagtgt tttgagctga atggcactcg ttttctagtt tgctctttga ttttaattgg
      361 gccttagtaa atactactct taaattaaac tatagtgaat tgaaataaga tgtgaacaac
      421 tctatcagaa
//
